CN104000890B - Traditional Chinese medicine for harmonizing liver and spleen, dispelling wind and eliminating dampness and nourishing blood and stopping throat pains - Google Patents

Abstract

The traditional Chinese medicine for harmonizing liver and spleen, expelling wind and removing dampness, nourishing blood and relieving numbness and pain disclosed by the present invention has the content of each composition raw material, by weight, and the main raw materials are: 10-30 grams of Qingfengteng, 15-30 grams of Sarcorrhizae, 15-30 grams of peony, 15-25 grams of angelica, 9-20 grams of herb, 6-15 grams of Fangfeng, 15-20 grams of fried Atractylodes macrocephala, 6-15 grams of Chuanxiong, auxiliary raw materials: 6-15 grams of raw licorice. This traditional Chinese medicine has a whole set of therapeutic effects such as harmonizing the liver and spleen, expelling wind and dampness, nourishing blood and relieving numbness and pain. It is especially suitable for patients with symptoms of rheumatic diseases (rheumatoid arthritis, etc.) such as muscle soreness, joint swelling, pain, poor flexion and extension, numbness, stiffness, and fatigue. Integrating treatment and support of righteousness, the medicine is safe and has no side effects. It can effectively improve the body's immunity while eliminating diseases. It effectively solves the problems of large side effects, great damage to the body, and poor therapeutic effect of the current drugs used to treat arthralgia syndrome.

Description

Traditional Chinese medicine for harmonizing liver and spleen, expelling wind and dampness, nourishing blood and relieving numbness and pain

technical field

The present invention belongs to the field of traditional Chinese medicine for treating rheumatic arthralgia syndrome, and in particular relates to a traditional Chinese medicine for harmonizing liver and spleen, expelling wind and dampness, nourishing blood and relieving arthralgia.

Background technique

Muscle soreness, joint swelling, pain, poor flexion and extension, numbness and stiffness, fatigue and other diseases such as rheumatism and rheumatoid arthritis belong to the category of "arthritis" in traditional Chinese medicine, also known as arthralgia syndrome. Arthralgia syndrome is mostly caused by wind, cold, dampness, and evil Diseases caused by invading meridians, skin, muscles, tendons, bones, qi and blood, causing paralysis. Arthralgia syndrome is a common clinical disease, frequently-occurring disease, long onset cycle, and diverse clinical symptoms. At present, there are a few traditional Chinese medicines, Chinese patent medicines, and western medicines used to treat this disease. Most of these medicines only contain anti-rheumatism. The components play an analgesic and relieving effect on the limbs showing symptoms, but they are difficult to cure the disease, and cause varying degrees of damage to the kidneys, etc., and long-term use will bring adverse consequences.

Contents of the invention

The object of the present invention is to provide a traditional Chinese medicine for harmonizing the liver and spleen, expelling wind and dampness, nourishing blood and relieving arthralgia, aiming at the manifestation symptoms of the aforementioned arthralgia syndrome and the deficiency of existing medicines. Reduce swelling and relieve pain, improve the clinical symptoms of patients such as joint muscle pain, stiffness, numbness, and fatigue.

The traditional Chinese medicine for harmonizing the liver and spleen, expelling wind and removing dampness, nourishing blood and relieving numbness and pain provided by the present invention is composed of the following raw materials, by weight, the main raw materials: 10-30 grams of Qingfengteng, 15-30 grams of Sarcorrhizae , 15-30 grams of white peony root, 15-25 grams of angelica, 9-20 grams of herb, 6-15 grams of Fangfeng, 15-20 grams of fried Atractylodes macrocephala, 6-15 grams of Chuanxiong, auxiliary raw materials: 6-15 grams of raw licorice.

According to needs, the proportion of the above-mentioned traditional Chinese medicines can be adjusted appropriately, and the preferred composition is, by weight, the main raw materials: 12-20 grams of Qingfengcao, 20-30 grams of Sarcorrhizae, 20-30 grams of Radix Paeoniae Alba, 20-25 grams of Angelica, Atractylodes 12-18 grams, Fangfeng 8-10 grams, fried Atractylodes macrocephala 19-20 grams, Chuanxiong 8-10 grams, auxiliary raw materials: raw licorice 10-15 grams. the

Among them, the most preferred composition, by weight, the main raw materials: 15 grams of Qingfengteng, 30 grams of sarcophagus, 30 grams of white peony root, 20 grams of angelica, 15 grams of herb, 9 grams of Fangfeng, 20 grams of fried Atractylodes macrocephala and 10 grams of Chuanxiong , Auxiliary raw materials: 12 grams of raw licorice.

The above ratio of raw materials is based on clinical trial data and obtained through scientific screening. For patients with different conditions, such as patients with mild symptoms, patients with very severe symptoms, or patients of different age groups, in order to achieve the same effect, each raw material should be guaranteed Under the condition that the ratio remains the same, the dose can be increased or decreased accordingly, but the range of change in the dose should not be too large, and should not exceed 20% of the dose.

In the present invention, Qingfengteng, Zhongjiefeng, Baishao, Angelica, Atractylodes, Fangfeng, Stir-fried Atractylodes Rhizome and Chuanxiong are the main active raw materials, and the content ratio must strictly abide by the raw material ratio. Reduce, harmonize the various active ingredients, and promote the efficacy of medicinal properties.

The traditional Chinese medicine provided by the present invention for harmonizing the liver and spleen, expelling wind and dampness, nourishing blood and relieving pain can be made into various forms of pharmaceutical dosage forms, such as decoction, oral liquid, extract, capsule, granule or pill, etc. Among them, decoctions, oral liquids and pills are preferred, and decoctions are most preferred.

Decoction preparation method: Ordinary water decoction, accurately weighed according to the proportion of raw materials, add 250 ml of water, decoct for 40 minutes for the first decoction, 20 minutes for the second decoction, filter the residue while hot, mix and concentrate the two decoctions to 200 ml, divide into two times. This method is simple and easy to implement, absorbs quickly, and has strong effect, and can give full play to the compatibility of the various raw materials of the traditional Chinese medicine, and quickly exert the medicinal effect.

Usage and Dosage: Oral administration, decoction according to the ratio of raw materials, oral use, one dose per day, it will start to take effect after ten days of taking, one month is a course of treatment, and three courses of treatment in a row.

The traditional Chinese medicine for harmonizing the liver and spleen, expelling wind and removing dampness, nourishing blood and relieving numbness and pain provided by the invention has the following functions and characteristics:

1. Effectively prevent, control and treat rheumatic arthralgia syndrome, with mild medicinal properties, combined with attacking evil and nourishing.

2. Pure Chinese medicine formula, no toxic side effects.

3. Mainly cure diseases, supplemented with nourishing medicine, treat both symptoms and root causes, and do not relapse after recovery.

4. Harmonize the liver and spleen, nourish blood and eliminate numbness, assist vitality, enhance immunity, and fundamentally improve the patient's susceptibility constitution.

The traditional Chinese medicine provided by the present invention for harmonizing liver and spleen, expelling wind and dampness, nourishing blood and relieving arthralgia, the pharmacological effects of each raw material are as follows:

Fructus Chinensis: bitter, flat. Dispelling rheumatism, promoting urination. Control rheumatic arthralgia, dredge channels and collaterals, crane knee wind, edema, beriberi.

Swollen joint wind: acrid in the mouth, flat in nature. Heat-clearing and detoxifying, antibacterial and anti-inflammatory, expelling wind and dampness, promoting blood circulation and relieving pain.

Paeoniae Alba: Bitter, sour, flat, slightly cold. Nourish blood and restrain yin, soothe liver and relieve pain, eliminate blood stagnation, acute pain of limbs, replenish qi, smooth blood

Pulse, moderate, disperses bad blood, drives away blood, lumbago.

Angelica: sweet, pungent, warm. Enriching blood and regulating menstruation, promoting blood circulation and relieving pain, treats abdominal pain due to deficiency and cold, bruises, arthralgia due to wind-cold.

Herb: pungent, bitter, warm. Drying dampness and invigorating the spleen, expelling wind and dispelling cold dominates rheumatic arthralgia.

Windproof: pungent, sweet, slightly warm. Expelling wind and dampness, relieving exterior pain and relieving pain, treats rheumatism arthralgia.

Fried Atractylodes Rhizoma: sweet, bitter, warm. Invigorating Qi and invigorating the spleen, drying dampness and promoting diuresis.

Rhizoma Chuanxiong: pungent, warm. Promoting blood circulation and promoting qi, expelling wind and relieving pain, treating blood stasis and qi stagnation pain, rheumatism arthralgia.

Raw licorice: sweet, flat. It has the effects of invigorating the spleen and replenishing qi, clearing heat and detoxifying, relieving spasms and relieving pain, and harmonizing various medicines.

The traditional Chinese medicine provided by the present invention has the beneficial effects of harmonizing the liver and spleen, expelling wind and dampness, nourishing blood and relieving pain, and has a complete set of therapeutic effects such as harmonizing the liver and spleen, expelling wind and removing dampness, nourishing blood and relieving pain. It is especially suitable for patients with symptoms of rheumatic diseases (rheumatoid arthritis, etc.) such as muscle soreness, joint swelling, pain, poor flexion and extension, numbness, stiffness, and fatigue. Integrating treatment and support of righteousness, the medicine is safe and has no side effects. It can effectively improve the body's immunity while eliminating diseases. It effectively solves the problems of large side effects, great damage to the body, and poor therapeutic effect of the current drugs used to treat arthralgia syndrome.

Detailed ways

In order to better understand the essence of the present invention, the following clinical trial data and specific examples are used to further illustrate the beneficial effects of using the traditional Chinese medicine of the present invention for harmonizing the liver and spleen, expelling wind and dampness, nourishing blood and relieving pain:

The disease applicable to the Chinese medicine of the present invention, the TCM diagnostic criteria of its symptoms: pain in joints, skin, muscles and bones, etc., or swelling morning stiffness, numbness, or difficulty in flexion and extension, and even swelling and deformation of the joints, swelling pain, or severe pain in the joints, Muscle atrophy, dull pain, anorexia, weight loss, irregular menstruation in women, especially numbness, palpitations, fatigue, etc.

Efficacy criteria

Recovery: all symptoms disappear, and functional activities return to normal;

Significant: All symptoms or main symptoms are eliminated, joint function is basically restored, joint function is restored, and normal work and labor can be performed;

Effective: The main symptoms basically disappeared, the main joint functions basically recovered or improved significantly, and the living and working ability recovered;

Invalid: Compared with before treatment, there is no progress in all aspects.

Clinical Trial Data

Test case criteria: patients who meet the diagnostic criteria of traditional Chinese medicine.

The present invention carries out clinical follow-up treatment on 200 cases of patients, including 100 cases of males and 100 cases of females, aged 15 to 80 years old, and the age distribution is as follows: 100 cases of 50 to 80 years old, 70 cases of 30 to 50 years old, 30 cases of 15 to 30 years old For example, after 3 years of clinical observation, the therapeutic effect is as follows:

60 cases of recurrent cases

After one month of medication: 8 cases were cured, 22 cases were significant, 60 cases were effective, and 0 cases were ineffective;

After two months of medication: 19 cases were cured, 45 cases were significant, 60 cases were effective, and 0 cases were ineffective;

After three months of medication: 27 cases were cured, 52 cases were marked, 60 cases were effective, and 0 cases were ineffective;

No recurrence;

140 typical cases

One month after medication: 76 cases were cured, 105 cases were marked, 140 cases were effective, and 0 cases were ineffective;

After two months of medication: 95 cases were cured, 116 cases were significant, 140 cases were effective, and 0 cases were ineffective;

After three months of medication: 109 cases were cured, 128 cases were marked, 140 cases were effective, and 0 cases were ineffective;

There were no recurrence cases.

Example 1

Patient information: Liu, female, 32 years old, had swollen and painful hands and foot joints for 3 years, and the effect of taking Chinese and Western medicines was not obvious.

Symptoms at the time of treatment: swelling and pain in the interphalangeal joints and metacarpophalangeal joints of the hands and proximal feet, difficulty in flexion and extension, numbness, morning stiffness for 1 hour, weight loss, fatigue, poor appetite, inability to work, red tongue, thin white fur, thready pulse .

Formula 1: Qingfengteng 12 grams, sarcophagus 20 grams, white peony 25 grams, angelica 18 grams, atractylodes 10 grams, Fangfeng 7 grams, fried Atractylodes macrocephala 19 grams, Chuanxiong 6 grams and raw licorice 8 grams.

Dosage: Ordinary water decoction, accurately weighed according to the formula, add 250 ml of water, decoct the first for 40 minutes, decoct the second for 20 minutes, filter the residue while it is hot, mix and concentrate the two decoctions to 200 ml, take it twice, each time One dose a day.

Effects: After taking it for 14 days, the joint swelling and pain were significantly reduced, joint activity improved, morning stiffness was relieved for 30 minutes, fatigue was relieved, and appetite improved. After taking it for 1 month, joint swelling and pain disappeared, joint activity improved, morning stiffness disappeared, and energy improved. The appetite was normal, the complexion turned rosy, the weight increased by 1 kg, and the normal work resumed.

Example 2

Patient information: Wang, female, 52 years old, had swollen and painful hands and joints for 6 years, accompanied by numbness and weakness in the shoulders and arms, and the effect of taking Chinese and Western medicines was not obvious.

Symptoms at the time of treatment: swelling and pain in the proximal interphalangeal joints and metacarpophalangeal joints of both hands, difficulty in flexion and extension, weakness in shoulders and arms, numbness and stiffness, limited mobility, weakness in lifting, sallow complexion, fatigue, poor appetite, pale tongue, thin white fur , thready and weak pulse.

Formula 2: 18 grams of Qingfengteng, 25 grams of sarcophagus, 25 grams of white peony, 22 grams of angelica, 12 grams of atractylodes, 8 grams of Fangfeng, 20 grams of fried Atractylodes macrocephala, 9 grams of Chuanxiong and 10 grams of raw licorice.

Usage and dosage: same as embodiment 1

Effects: After taking it for 2 months, the joint swelling and pain disappeared, the numbness and weakness of the shoulders and arms were obviously improved, the activities were flexible, the complexion was rosy, the energy was obviously improved, the appetite improved, the tongue was light red, and the fur was thin and white.

Example 3

Patient information: Li, male, 60 years old, suffered from stiffness and tingling of joints and muscles all over the body for 6 years, and recurrent attacks, and the effect of taking Chinese and Western medicines was not obvious.

Symptoms at the time of treatment: swelling, pain, and tingling of the proximal interphalangeal joints and metacarpophalangeal joints of both hands, shoulder and arm weakness, numbness, stiffness, and pain, muscle stiffness and pain throughout the body, limited mobility, weakness in lifting, restlessness in sitting up, and dull complexion , Pale lips, weight loss, fatigue, poor appetite, restless sleep at night, irritability, affecting normal life, dull tongue, ecchymosis, thin white fur, thready and weak pulse.

Recipe 3: Qingfengteng 15g, Swollen Rhizome 30g, Paeoniae Alba 30g, Angelica 20g, Atractylodes 15g, Fangfeng 9g, Stir-fried Atractylodes Rhizoma 20g, Rhizoma Chuanxiong 10g and Raw Licorice 12g.

Usage and dosage: same as embodiment 1

Effects: After 2 months of medication, the tingling pain in the muscles and joints of the whole body disappeared, the numbness and weakness of the shoulders and arms improved significantly, the activities were more flexible, the energy and food intake improved, the sleep improved, the complexion and tongue were rosier than before, and the life can be taken care of. Significantly improved.

Treatment result analysis: in summary, by the statistical data of clinical patients, it is shown that the effective rate of the present invention for the treatment of rheumatic arthralgia syndrome reaches 100%, the significant rate is more than 90%, and the recovery rate reaches 68%. It is proved that the traditional Chinese medicine of the present invention has remarkable effects of nourishing blood and dredging collaterals, expelling wind and dampness, reducing swelling and relieving numbness and pain. the

Claims (3)

1. the Chinese medicine of a regulating the liver and spleen, expelling wind and removing dampness, the stopping numbness pain that nourishes blood, it is characterized in that: be made up of following crude drug, by weight, primary raw material: Caulis Sinomenii 10 ~ 30 grams, Herba Sarcandrae 15 ~ 30 grams, the Radix Paeoniae Alba 15 ~ 30 grams, Radix Angelicae Sinensis 15 ~ 25 grams, Rhizoma Atractylodis 9 ~ 20 grams, Radix Saposhnikoviae 6 ~ 15 grams, Rhizoma Atractylodis Macrocephalae (parched) 15 ~ 20 grams and Rhizoma Chuanxiong 6 ~ 15 grams, auxiliary material: Radix Glycyrrhizae 6 ~ 15 grams.

2. the Chinese medicine of regulating the liver and spleen according to claim 1, expelling wind and removing dampness, the stopping numbness pain that nourishes blood, it is characterized in that: described primary raw material is: Caulis Sinomenii 12 ~ 20 grams, Herba Sarcandrae 20 ~ 30 grams, the Radix Paeoniae Alba 20 ~ 30 grams, Radix Angelicae Sinensis 20 ~ 25 grams, Rhizoma Atractylodis 12 ~ 18 grams, Radix Saposhnikoviae 8 ~ 10 grams, Rhizoma Atractylodis Macrocephalae (parched) 19 ~ 20 and Rhizoma Chuanxiong 8 ~ 10 grams, described auxiliary material is: Radix Glycyrrhizae 10 ~ 15 grams.

3. the Chinese medicine of regulating the liver and spleen according to claim 2, expelling wind and removing dampness, the stopping numbness pain that nourishes blood, it is characterized in that: described primary raw material is: Caulis Sinomenii 15 grams, Herba Sarcandrae 30 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 20 grams, Rhizoma Atractylodis 15 grams, Radix Saposhnikoviae 9 grams, Rhizoma Atractylodis Macrocephalae (parched) 20 grams and Rhizoma Chuanxiong 10 grams, described auxiliary material is: Radix Glycyrrhizae 12 grams.