CN103393840A - Traditional Chinese medicine composition for treating osteoarthritis - Google Patents
Traditional Chinese medicine composition for treating osteoarthritis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating osteoarthritis. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-40 parts of radix astragali, 10-30 parts of angelica sinensis, 10-40 parts of radix paeoniae alba, 10-40 parts of lycium barbarum, 10-30 parts of cornus officinalis, 5-25 parts of eucommia ulmoides, 5-25 parts of dipsacus root, 10-40 part of parasitic loranthus, 5-20 parts of rhizoma cibotii, 5-20 parts of achyranthes root, 5-20 parts of gentiana macrophylla, 5-20 parts of radix clematidis, 10-40 parts of caulis spatholobi, 5-20 parts of safflower carthamus, 5-20 parts of frankincense, 5-20 parts of myrrh, 10-40 parts of papaw, 5-20 parts of lycopodium clavatum, 5-20 parts of morinda officinalis, 10-40 parts of herba epimedii, 5-25 parts of cassia twig and 5-15 parts of liquorice. The traditional Chinese medicine composition in the invention has the effects of nourishing liver and kidney, expelling wind and removing cold, activating blood and dissolving stasis, clearing damp and relieving pain and dredging the meridian, and is effective in the treatment of osteoarthritis and reliable in curative effects.
Description
Technical field
The present invention relates to a kind of not pharmaceutical product of definite structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of osteoarthritis.
Background technology
Osteoarthritis (osteoarthritis, OA) also claims degenerative osteoarthritis, is a kind of degeneration take articular cartilage, destruction and the hyperosteogeny chronic joint disease as feature.Be mainly in middle-aged and elderly people.Osteoarthritis belongs to Chinese medicine " rheumatism involving the bone ", " knee joint numbness " category.Main manifestations is arthralgia and movable dumb, and X line performance joint space narrows down, and subchondral bone matter is fine and close, and the bone trabecula fracture, have sclerosis and cystis degeneration, and there is lip sample hypertrophy at the edge, joint, later stage epiphysis distortion, and articular surface is uneven.At present, western medical treatment comprises operative treatment, non-operative treatment and naturopathy.Operative treatment itself is exactly a kind of traumatic treatment, and is prone to infection, blood vessel, nerve injury, and skin, osteonecrosis, the bad complication such as joint motion is limited, curative effect is also unstable; What non-operative treatment was the most frequently used is exactly to take analgesic and antibiotic medicine, but this method can't solve the basic Autoimmune Disorders pathomechanism of osteoarthritis, and this type of medicine of long-term taking can cause addiction to rely on and gastrointestinal destroys; Though naturopathy has certain effect, the course for the treatment of is long, and curative effect is not consolidated.
The traditional Chinese medical science thinks, osteoarthritis is caused by liver and kidney deficiency, the evil invasion muscles and bones of wind and cold wet three, and phlegm-damp blood stasis knot is sent out with joint and is pain,, take deficiency in origin and excess in superficiality as card, therefore control, should work as with invigorating the liver and kidney, wind-damp dispelling, QI invigorating, invigorates blood circulation as.
, according to theory of Chinese medical science,, for the pathogeny of osteoarthritis, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
The deficiency that operative treatment osteoarthritis wound in prior art is large in order to overcome, non-operative treatment and naturopathy osteoarthritis only play relief of symptoms, cure the symptoms, not the disease, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of evident in efficacy, the treatment osteoarthritis that has no side effect.
the technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Astragali 10-40 part, Radix Angelicae Sinensis 10-30 part, Radix Paeoniae Alba 10-40 part, Fructus Lycii 10-40 part, Fructus Corni 10-30 part, Cortex Eucommiae 5-25 part, Radix Dipsaci 5-25 part, Herba Taxilli 10-40 part, Rhizoma Cibotii 5-20 part, Radix Achyranthis Bidentatae 5-20 part, Radix Gentianae Macrophyllae 5-20 part, Radix Clematidis 5-20 part, Caulis Spatholobi 10-40 part, Flos Carthami 5-20 part, Olibanum 5-20 part, Myrrha 5-20 part, Fructus Chaenomelis 10-40 part, Herba Lycopodii 5-20 part, Radix Morindae Officinalis 5-20 part, Herba Epimedii 10-40 part, Ramulus Cinnamomi 5-25 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of osteoarthritis is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 30 parts of the Radixs Astragali, 20 parts of Radix Angelicae Sinensis, 30 parts of the Radix Paeoniae Albas, 30 parts of Fructus Lyciis, 20 parts of Fructus Corni, 15 parts of the Cortexs Eucommiae, 15 parts of Radix Dipsaci, 30 parts of Herba Taxillis, 12 parts of Rhizoma Cibotii, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Radix Gentianae Macrophyllae, 10 parts of Radix Clematidis, 30 parts of Caulis Spatholobis, 10 parts, Flos Carthami, 10 parts of Olibanums, 10 parts of Myrrhas, 30 parts of Fructus Chaenomeliss, 10 parts of Herba Lycopodiis, 10 parts of Radix Morindae Officinaliss, 30 parts of Herba Epimedii, 15 parts of Ramulus Cinnamomi, 6 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Astragali has the effect that benefiting QI for strengthening the superficies, arresting sweating take off, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema admittedly; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, the effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation; The Radix Paeoniae Alba has the effect of clear and coherent blood vessels, nourishing blood to suppress the hyperactive liver, slow middle arresting sweating; Fructus Lycii has the effect of nourishing the liver and kidney, nourishing the liver to improve visual acuity, strengthening the body resistance, spermatogenesis benefit marrow, enriching yin and nourishing kidney, benefiting vital QI for tranquillizing; Fructus Corni has the effect of liver and kidney tonifying, essence astringing and desertion stemming; The Cortex Eucommiae has the effect of invigorating the liver and kidney, bone and muscle strengthening, invigorating middle warmer benefit vital essence; Radix Dipsaci has the effect of invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating; Herba Taxilli has the effect of invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit; Rhizoma Cibotii has the effect in invigorating the liver and kidney, strong spinal column, wind-damp dispelling, sharp joint; Radix Achyranthis Bidentatae has the effect of invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards; Radix Gentianae Macrophyllae has the effect of Eradicates rheumatism, Shujin network, clearind deficient heat; Radix Clematidis has the effect of expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump; Caulis Spatholobi has to enrich blood invigorates blood circulation, relaxes through the effect of collateral dredging; Flos Carthami has the effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Olibanum has the effect of blood-activating and qi-promoting, pain relieving, detumescence and promoting granulation; Myrrha has the effect of loose blood blood stasis removing, subduing swelling and relieving pain; Fructus Chaenomelis has the effect of suppressing the hyperactive liver Shujin, stomach function regulating removing dampness; Herba Lycopodii has the effect of expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation; Radix Morindae Officinalis has the effect of reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness; Herba Epimedii have kidney-replenishing, bone and muscle strengthening, wind-damp dispelling effect; Ramulus Cinnamomi has the effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component be through dialectical compatibility, helps using mutual assistant, plays altogether nourishing liver and kidney, expelling wind and cold, blood circulation promoting and blood stasis dispelling, damp-clearing pain-relieving, relaxes through the effect of collateral dredging, and the treatment of osteoarthritis is reached treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, toxic and side effects do not occur, and effective percentage reaches 94%, cure rate 64%.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 30g, Radix Angelicae Sinensis 20g, Radix Paeoniae Alba 30g, Fructus Lycii 30g, Fructus Corni 20g, Cortex Eucommiae 15g, Radix Dipsaci 15g, Herba Taxilli 30g, Rhizoma Cibotii 12g, Radix Achyranthis Bidentatae 10g, Radix Gentianae Macrophyllae 10g, Radix Clematidis 10g, 30 parts of Caulis Spatholobis, Flos Carthami 10g, Olibanum 10g, Myrrha 10g, Fructus Chaenomelis 30g, Herba Lycopodii 10g, Radix Morindae Officinalis 10g, Herba Epimedii 30g, Ramulus Cinnamomi 15g, Radix Glycyrrhizae 6g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 10g, Radix Angelicae Sinensis 30g, Radix Paeoniae Alba 15g, Fructus Lycii 40g, Fructus Corni 10g, Cortex Eucommiae 25g, Radix Dipsaci 5g, Herba Taxilli 35g, Rhizoma Cibotii 10g, Radix Achyranthis Bidentatae 20g, Radix Gentianae Macrophyllae 5g, Radix Clematidis 15g, 10 parts of Caulis Spatholobis, Flos Carthami 20g, Olibanum 15g, Myrrha 5g, Fructus Chaenomelis 40g, Herba Lycopodii 5g, Radix Morindae Officinalis 20g, Herba Epimedii 10g, Ramulus Cinnamomi 25g, Radix Glycyrrhizae 5g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 40g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 25g, Fructus Lycii 15g, Fructus Corni 15g, Cortex Eucommiae 10g, Radix Dipsaci 20g, Herba Taxilli 10g, Rhizoma Cibotii 20g, Radix Achyranthis Bidentatae 5g, Radix Gentianae Macrophyllae 15g, Radix Clematidis 12g, 40 parts of Caulis Spatholobis, Flos Carthami 5g, Olibanum 20g, Myrrha 12g, Fructus Chaenomelis 10g, Herba Lycopodii 20g, Radix Morindae Officinalis 5g, Herba Epimedii 30g, Ramulus Cinnamomi 5g, Radix Glycyrrhizae 12g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 25g, Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 10g, Fructus Lycii 20g, Fructus Corni 30g, Cortex Eucommiae 5g, Radix Dipsaci 12g, Herba Taxilli 20g, Rhizoma Cibotii 15g, Radix Achyranthis Bidentatae 12g, Radix Gentianae Macrophyllae 20g, Radix Clematidis 5g, 25 parts of Caulis Spatholobis, Flos Carthami 12g, Olibanum 5g, Myrrha 20g, Fructus Chaenomelis 35g, Herba Lycopodii 12g, Radix Morindae Officinalis 15g, Herba Epimedii 25g, Ramulus Cinnamomi 20g, Radix Glycyrrhizae 10g.
Embodiment 5
A kind of Chinese medicine composition for the treatment of osteoarthritis, its raw material of Chinese medicine and weight proportion are: Radix Astragali 35g, Radix Angelicae Sinensis 25g, Radix Paeoniae Alba 40g, Fructus Lycii 10g, Fructus Corni 25g, Cortex Eucommiae 20g, Radix Dipsaci 25g, Herba Taxilli 40g, Rhizoma Cibotii 5g, Radix Achyranthis Bidentatae 15g, Radix Gentianae Macrophyllae 12g, Radix Clematidis 20g, 35 parts of Caulis Spatholobis, Flos Carthami 15g, Olibanum 12g, Myrrha 15g, Fructus Chaenomelis 25g, Herba Lycopodii 15g, Radix Morindae Officinalis 12g, Herba Epimedii 35g, Ramulus Cinnamomi 10g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15～20 minutes, then add water and do not have approximately 8 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, boil rear with slow fire boiling 20～30 minutes; Decoct for the second time, add water and do not have approximately 5 centimetres of powder, decoct, the water rear decoction 15～20 minutes of boiling.Decoct extracting juice twice, merge.
The present invention, with the given a kind of Chinese medicine composition for the treatment of osteoarthritis of embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 50 examples, man 22, female's 28 examples, 45～75 years old age.
Two, diagnosis basis: the osteoarthritis diagnostic criteria of reference State Administration of Traditional Chinese Medicine's " traditional Chinese medical science disease Standardization of diagnosis and curative effect " in 1994 formulation:
1, mostly be middle-aged and elderly people;
2, the periarticular pain of outbreak repeatedly, when bear a heavy burden in joint, pain increases the weight of, the time swelling arranged;
Coarse joint crepitus is arranged while 3, bending and stretching joint more;
4, x-ray shows edge, joint hyperosteogeny, and joint space obviously narrows down;
5, rheumatoid arthritis except.
Three, usage and dosage: during clinical practice, potion on the one, twice extracting juice of decocting be 300ml approximately, divides early, takes for late twice.Five days is a course for the treatment of.Period in a medicine is avoided the irritable foods such as vinegar-pepper, greasy.
Four, criterion of therapeutical effect: the osteoarthritis efficacy assessment standard of reference State Administration of Traditional Chinese Medicine's " traditional Chinese medical science disease Standardization of diagnosis and curative effect " in 1994 formulation:
(1), cure: pain disappears, and it is normal that joint movement function recovers;
(2), produce effects: pain obviously alleviates, and joint movement function improves;
(3), effective: pain alleviates to some extent, and joint motion makes moderate progress;
(4), invalid: arthralgia and range of activity are without improvement.
Five, therapeutic effect: in this clinical observation case, take medicine 2-8 the course for the treatment of, recovery from illness 32 examples, follow up a case by regular visits to and have no recurrence; Produce effects 10 examples, effective 5 examples, invalid 3 examples.Toxic and side effects does not occur during treatment.
Six, model case:
Case 1:
Cold certain, female, 45 years old.Double knee joint pain appearred before 3 years, limitation of activity, Drug therapys such as oral meloxicam, acetaminophen once, but poor effect.Double knee joint pain increases the weight of in this year, and film making shows the double knee joint regression, and joint space is asymmetric, is diagnosed as: two knee osteoarthritiss.Take 3 courses for the treatment of of medicament of Chinese medicine composition of the present invention preparation, conscious double knee joint pain obviously alleviates before; Continue to take 2 courses for the treatment of, pain disappears, and it is normal that joint movement function recovers.
Case 2:
Yao, man, 57 years old.Two knee joint swelling, weak, pain, squat down limited.Swelling, the pain symptom aggravation of double knee joint appears in the later stage.Be diagnosed as: two knee osteoarthritiss.Take 2 courses for the treatment of of medicament of Chinese medicine composition preparation of the present invention, double knee joint pain, swelling alleviate greatly, and the function of squatting down is obviously improved; Continue to take 3 courses for the treatment of, two knee joint swelling, weak, pain disappear, squat down and other movable functions recover normal.Follow up a case by regular visits to and do not recur half a year.
Claims (2)
1. Chinese medicine composition for the treatment of osteoarthritis, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Astragali 10-40 part, Radix Angelicae Sinensis 10-30 part, Radix Paeoniae Alba 10-40 part, Fructus Lycii 10-40 part, Fructus Corni 10-30 part, Cortex Eucommiae 5-25 part, Radix Dipsaci 5-25 part, Herba Taxilli 10-40 part, Rhizoma Cibotii 5-20 part, Radix Achyranthis Bidentatae 5-20 part, Radix Gentianae Macrophyllae 5-20 part, Radix Clematidis 5-20 part, Caulis Spatholobi 10-40 part, Flos Carthami 5-20 part, Olibanum 5-20 part, Myrrha 5-20 part, Fructus Chaenomelis 10-40 part, Herba Lycopodii 5-20 part, Radix Morindae Officinalis 5-20 part, Herba Epimedii 10-40 part, Ramulus Cinnamomi 5-25 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of osteoarthritis according to claim 1, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 30 parts of the Radixs Astragali, 20 parts of Radix Angelicae Sinensis, 30 parts of the Radix Paeoniae Albas, 30 parts of Fructus Lyciis, 20 parts of Fructus Corni, 15 parts of the Cortexs Eucommiae, 15 parts of Radix Dipsaci, 30 parts of Herba Taxillis, 12 parts of Rhizoma Cibotii, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Radix Gentianae Macrophyllae, 10 parts of Radix Clematidis, 30 parts of Caulis Spatholobis, 10 parts, Flos Carthami, 10 parts of Olibanums, 10 parts of Myrrhas, 30 parts of Fructus Chaenomeliss, 10 parts of Herba Lycopodiis, 10 parts of Radix Morindae Officinaliss, 30 parts of Herba Epimedii, 15 parts of Ramulus Cinnamomi, 6 parts, Radix Glycyrrhizae.
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| CN104606383A (en) * | 2015-01-25 | 2015-05-13 | 董艳丽 | Traditional Chinese medicine composition for treating osteoarthritis |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015651A (en) * | 2007-03-01 | 2007-08-15 | 陈守杰 | Medicine for treating protrusion of lumbar intervertebral disc |
| CN101411802A (en) * | 2008-11-21 | 2009-04-22 | 赵献民 | Black plaster for treating hyperosteogeny and preparation method thereof |
| CN102188538A (en) * | 2011-03-22 | 2011-09-21 | 张彦 | Chinese medicine for treating hyperosteogeny of cervical vertebra and lumbar vertebrae |
-
2013
- 2013-07-24 CN CN201310313234.7A patent/CN103393840B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015651A (en) * | 2007-03-01 | 2007-08-15 | 陈守杰 | Medicine for treating protrusion of lumbar intervertebral disc |
| CN101411802A (en) * | 2008-11-21 | 2009-04-22 | 赵献民 | Black plaster for treating hyperosteogeny and preparation method thereof |
| CN102188538A (en) * | 2011-03-22 | 2011-09-21 | 张彦 | Chinese medicine for treating hyperosteogeny of cervical vertebra and lumbar vertebrae |
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