CN104225407A - Obstetrics and gynecology drug for treating postnatal depression and production method thereof - Google Patents

Obstetrics and gynecology drug for treating postnatal depression and production method thereof Download PDF

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CN104225407A
CN104225407A CN201410530380.XA CN201410530380A CN104225407A CN 104225407 A CN104225407 A CN 104225407A CN 201410530380 A CN201410530380 A CN 201410530380A CN 104225407 A CN104225407 A CN 104225407A
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radix
rhizoma
herba
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obstetrics
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夏放军
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Abstract

The invention discloses an obstetrics and gynecology drug for treating postnatal depression and a production method thereof. The obstetrics and gynecology drug for treating postnatal depression is produced from the following raw materials of saffron, pseudo-ginseng, wine angelica roots, vinegar rhizoma cyperi, vinegar rhizoma corydalis, costus roots, raw peach kernels, wine Sichuan lovage rhizome, roasted Chinese thorowax roots, lightyellow sophora roots, common cnidium fruit, amur corktree barks, hairy fig, motherwort herb, Chinese mugwort, Chinese red pepper, sessile stemona roots, bunge corydalis herb, Chinese rhubarb, sargentgloryvine stems, common knotgrass herb, fructus kochiae, aluminum potassium sulfate, rhizoma atractylodis, seeds of Job's tears, ginseng, Chinese yam, gordon euryale seeds, himalayan teasel roots, bighead atractylodes rhizome, licorice roots, oyster shells, humifuse euphorbia herb, Chinese honeylocust spine, milkvetch roots, borneol, dahurian patrinia herb, and dandelion. The obstetrics and gynecology drug for treating postnatal depression has the advantages of being obvious in curative effect and few in side effects.

Description

A kind of department of obstetrics and gynecology medicine for the treatment of postpartum depression and preparation method thereof
Technical field
The present invention relates to a kind of department of obstetrics and gynecology medicine for the treatment of postpartum depression and preparation method thereof.
Background technology
Department of obstetrics and gynecology are one of large main subjects of clinical medicine four, the main research cause of disease of disease of female genital organs, pathology, diagnosis and control, the increasing people of progress along with the epoch follows late marriage and childbirth, allows lying-in woman advanced in years increase year by year, and thing followed obstetrical and gynecological disease also gets more and more.In order to treat these diseases, also occurred various medicine on the market, major part is all Western medicine formula, although have certain curative effect, can very large to the side effect of human body, and all cures the symptoms, not the disease due to Western medicine, so recurrence probability after drug withdrawal very large; In addition, the medicine of some Chinese and Western combined formulation, although less than the drug side effect of pure Western medicine formula, can curative effect does not have the good of pure Western medicine also.
Summary of the invention
Technical problem to be solved by this invention is to provide one and has evident in efficacy, and the department of obstetrics and gynecology medicine of the treatment postpartum depression had no side effect.
For solving the problem, the present invention is achieved through the following technical solutions:
Treat a department of obstetrics and gynecology medicine for postpartum depression, the department of obstetrics and gynecology medicine of described treatment postpartum depression is made up of following raw material: Stigma Croci, Radix Notoginseng, Radix Angelicae Sinensis (processed with wine), Rhizoma Cyperi (processed with vinegar), vinegar Rhizoma Corydalis, Radix Aucklandiae (Radix Vladimiriae), raw peach kernel, prepared RHIZOMA CHUAN XIONG with yellow rice wine, process Radix Bupleuri, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Herba Fici Simplicissimae, Herba Leonuri, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, the Radix Stemonae, Herba Corydalis Bungeanae, Radix Et Rhizoma Rhei, Caulis Sargentodoxae, Formica fusca grass, the Fructus Kochiae, dried Alumen, Rhizoma Atractylodis, Semen Coicis, Radix Ginseng, Rhizoma Dioscoreae, Semen euryales, Radix Dipsaci, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Concha Ostreae, cotton, Spina Gleditsiae, the Radix Astragali, Borneolum Syntheticum, Herba Patriniae and Herba Taraxaci, described raw material comprises following parts by weight proportioning: Stigma Croci 30g, Radix Notoginseng 20g, Radix Angelicae Sinensis (processed with wine) 45g, Rhizoma Cyperi (processed with vinegar) 30g, vinegar Rhizoma Corydalis 25g, Radix Aucklandiae (Radix Vladimiriae) 25g, raw peach kernel 30g, prepared RHIZOMA CHUAN XIONG with yellow rice wine 50g, process Radix Bupleuri 25g, Radix Sophorae Flavescentis 40g, Fructus Cnidii 20g, Cortex Phellodendri 15g, Herba Fici Simplicissimae 25g, Herba Leonuri 30g, Folium Artemisiae Argyi 10g, Pericarpium Zanthoxyli 20g, Radix Stemonae 15g, Herba Corydalis Bungeanae 35g, Radix Et Rhizoma Rhei 20g, Caulis Sargentodoxae 30g, Formica fusca grass 45g, Fructus Kochiae 20g, dried Alumen 10g, Rhizoma Atractylodis 15g, Semen Coicis 30g, Radix Ginseng 15g, Rhizoma Dioscoreae 20g, Semen euryales 12g, Radix Dipsaci 10g, Rhizoma Atractylodis Macrocephalae 7g, Radix Glycyrrhizae 15g, Concha Ostreae 10g, the cotton 20g in ground, Spina Gleditsiae 30g, Radix Astragali 35g, Borneolum Syntheticum 10g, Herba Patriniae 20g and Herba Taraxaci 20g.
Another technical problem to be solved by this invention is to provide one and has evident in efficacy, and the manufacture method of the department of obstetrics and gynecology medicine of the treatment postpartum depression had no side effect.
For solving the problems of the technologies described above, the present invention adopts following technical scheme: comprise the following steps:
A, cut off by Radix Ginseng 15g, adding distil water, the water yield there was not medicine 5 centimetres, with slow fire boiling after 6 hours, used 300 mesh screen, extracted medicinal liquid, for subsequent use;
B, by Radix Angelicae Sinensis (processed with wine) 45g, vinegar Rhizoma Corydalis 25g, raw peach kernel 30g, prepared RHIZOMA CHUAN XIONG with yellow rice wine 50g and process Radix Bupleuri 25g and put into the medicinal liquid that step " A " extracts, soak 4 hours, take out afterwards, for subsequent use;
C, by Stigma Croci 30g, Radix Notoginseng 20g, Rhizoma Cyperi (processed with vinegar) 30g, Radix Aucklandiae (Radix Vladimiriae) 25g, Radix Sophorae Flavescentis 40g, Fructus Cnidii 20g, Cortex Phellodendri 15g, Herba Fici Simplicissimae 25g, Herba Leonuri 30g, Folium Artemisiae Argyi 10g, Pericarpium Zanthoxyli 20g, Radix Stemonae 15g, Herba Corydalis Bungeanae 35g, Radix Et Rhizoma Rhei 20g, Caulis Sargentodoxae 30g, Formica fusca grass 45g, Fructus Kochiae 20g, dried Alumen 10g, Rhizoma Atractylodis 15g, Semen Coicis 30g, Rhizoma Dioscoreae 20g, Semen euryales 12g, Radix Dipsaci 10g, Rhizoma Atractylodis Macrocephalae 7g, Radix Glycyrrhizae 15g, Concha Ostreae 10g, the cotton 20g in ground, Spina Gleditsiae 30g, Radix Astragali 35g, Borneolum Syntheticum 10g, Herba Patriniae 20g and Herba Taraxaci 20g decocts with water 3 times, the water yield was advisable there not to be powder, decocting time is 5 hours for the first time, second time decocting time is 3 hours, decocting time is 2 hours for the third time, 18 hours are left standstill after decocting, use 500 mesh screen, extraction medicinal liquid is for subsequent use,
D, step " B " is soaked after the medical material that extracts add in the medicinal liquid that extracts in step " C ", decoct twice, first time decocts 3 hours, and second time decocts 2 hours, afterwards with 500 mesh screen extraction medicinal liquids, for subsequent use;
E, the medicinal liquid extracted in step " D " is added conventional debugger agent, PH is adjusted to by the thick shape of Concentration Modulation 1.4 after 4.5, leaves standstill 12 hours, for subsequent use;
F, step " E " is left standstill the thick shape medicament after 12 hours make pill, packaging completes.
The present invention treats the pharmacology introduction of part Chinese herbal medicine in the department of obstetrics and gynecology medicine of postpartum depression:
1, Stigma Croci: sweet in the mouth, property is put down, and has blood circulation promoting and blood stasis dispelling, the effect of dispersing stagnation and relieving accumulation of pathogens and pain relieving.
2, Herba Patriniae: acrid in the mouth, hardship, cool in nature, there is heat-clearing and toxic substances removing, the effect of detumescence and apocenosis.
3, prepared RHIZOMA CHUAN XIONG with yellow rice wine: acrid in the mouth, warm in nature, there is blood-activating and qi-promoting, the effect of wind-expelling pain-stopping.
4, the Radix Stemonae: sweet in the mouth, hardship, cold nature, has the effect of nourishing the lung to arrest cough.
5, Radix Notoginseng: sweet in the mouth, micro-hardship, warm in nature, there is the effect of hemostasis dissipating blood stasis, supplementing QI for promoting the production of body fluid, subduing swelling and relieving pain.
6, Radix Angelicae Sinensis (processed with wine): sweet in the mouth, pungent, bitter, warm in nature, has the effect of promoting blood circulation to restore menstrual flow.
7, Rhizoma Cyperi (processed with vinegar): acrid in the mouth, micro-hardship, property is put down, and has the effect of resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.
8, vinegar Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature, there is the effect of blood-activating and qi-promoting, menstruction regulating and pain relieving.
9, Radix Aucklandiae (Radix Vladimiriae): acrid in the mouth, hardship, warm in nature, there is the effect of promoting the circulation of QI to relieve pain, warming middle-JIAO for easing the stomach.
10, raw peach kernel: bitter in the mouth, sweet, property is put down, and has blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, the effect of relieving cough and asthma.
11, Radix Sophorae Flavescentis: bitter in the mouth, cold in nature, there is the effect of heat clearing and damp drying.
12, Semen Coicis: sweet in the mouth, light, cold nature, has invigorating spleen to remove dampness, the effect of clearing away heat and discharging pus.
13, the Radix Astragali: sweet in the mouth, slightly warm in nature, has the effect of inducing diuresis to remove edema, consolidating superficial resistance arresting sweating, the evacuation of pus of holder skin ulcer.
The beneficial effect of a kind of department of obstetrics and gynecology medicine for the treatment of postpartum depression of the present invention and preparation method thereof is: adopt pure Chinese drug preparation to form, side effect is low, and evident in efficacy.
Detailed description of the invention
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.
Embodiment
Treat a department of obstetrics and gynecology medicine for postpartum depression, the department of obstetrics and gynecology medicine of described treatment postpartum depression is made up of following raw material: Stigma Croci, Radix Notoginseng, Radix Angelicae Sinensis (processed with wine), Rhizoma Cyperi (processed with vinegar), vinegar Rhizoma Corydalis, Radix Aucklandiae (Radix Vladimiriae), raw peach kernel, prepared RHIZOMA CHUAN XIONG with yellow rice wine, process Radix Bupleuri, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Herba Fici Simplicissimae, Herba Leonuri, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, the Radix Stemonae, Herba Corydalis Bungeanae, Radix Et Rhizoma Rhei, Caulis Sargentodoxae, Formica fusca grass, the Fructus Kochiae, dried Alumen, Rhizoma Atractylodis, Semen Coicis, Radix Ginseng, Rhizoma Dioscoreae, Semen euryales, Radix Dipsaci, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Concha Ostreae, cotton, Spina Gleditsiae, the Radix Astragali, Borneolum Syntheticum, Herba Patriniae and Herba Taraxaci, described raw material comprises following parts by weight proportioning: Stigma Croci 30g, Radix Notoginseng 20g, Radix Angelicae Sinensis (processed with wine) 45g, Rhizoma Cyperi (processed with vinegar) 30g, vinegar Rhizoma Corydalis 25g, Radix Aucklandiae (Radix Vladimiriae) 25g, raw peach kernel 30g, prepared RHIZOMA CHUAN XIONG with yellow rice wine 50g, process Radix Bupleuri 25g, Radix Sophorae Flavescentis 40g, Fructus Cnidii 20g, Cortex Phellodendri 15g, Herba Fici Simplicissimae 25g, Herba Leonuri 30g, Folium Artemisiae Argyi 10g, Pericarpium Zanthoxyli 20g, Radix Stemonae 15g, Herba Corydalis Bungeanae 35g, Radix Et Rhizoma Rhei 20g, Caulis Sargentodoxae 30g, Formica fusca grass 45g, Fructus Kochiae 20g, dried Alumen 10g, Rhizoma Atractylodis 15g, Semen Coicis 30g, Radix Ginseng 15g, Rhizoma Dioscoreae 20g, Semen euryales 12g, Radix Dipsaci 10g, Rhizoma Atractylodis Macrocephalae 7g, Radix Glycyrrhizae 15g, Concha Ostreae 10g, the cotton 20g in ground, Spina Gleditsiae 30g, Radix Astragali 35g, Borneolum Syntheticum 10g, Herba Patriniae 20g and Herba Taraxaci 20g.
Described a kind of preparation process for the treatment of the department of obstetrics and gynecology medicine of postpartum depression is as follows:
A, cut off by Radix Ginseng 15g, adding distil water, the water yield there was not medicine 5 centimetres, with slow fire boiling after 6 hours, used 300 mesh screen, extracted medicinal liquid, for subsequent use;
B, by Radix Angelicae Sinensis (processed with wine) 45g, vinegar Rhizoma Corydalis 25g, raw peach kernel 30g, prepared RHIZOMA CHUAN XIONG with yellow rice wine 50g and process Radix Bupleuri 25g and put into the medicinal liquid that step " A " extracts, soak 4 hours, take out afterwards, for subsequent use;
C, by Stigma Croci 30g, Radix Notoginseng 20g, Rhizoma Cyperi (processed with vinegar) 30g, Radix Aucklandiae (Radix Vladimiriae) 25g, Radix Sophorae Flavescentis 40g, Fructus Cnidii 20g, Cortex Phellodendri 15g, Herba Fici Simplicissimae 25g, Herba Leonuri 30g, Folium Artemisiae Argyi 10g, Pericarpium Zanthoxyli 20g, Radix Stemonae 15g, Herba Corydalis Bungeanae 35g, Radix Et Rhizoma Rhei 20g, Caulis Sargentodoxae 30g, Formica fusca grass 45g, Fructus Kochiae 20g, dried Alumen 10g, Rhizoma Atractylodis 15g, Semen Coicis 30g, Rhizoma Dioscoreae 20g, Semen euryales 12g, Radix Dipsaci 10g, Rhizoma Atractylodis Macrocephalae 7g, Radix Glycyrrhizae 15g, Concha Ostreae 10g, the cotton 20g in ground, Spina Gleditsiae 30g, Radix Astragali 35g, Borneolum Syntheticum 10g, Herba Patriniae 20g and Herba Taraxaci 20g decocts with water 3 times, the water yield was advisable there not to be powder, decocting time is 5 hours for the first time, second time decocting time is 3 hours, decocting time is 2 hours for the third time, 18 hours are left standstill after decocting, use 500 mesh screen, extraction medicinal liquid is for subsequent use,
D, step " B " is soaked after the medical material that extracts add in the medicinal liquid that extracts in step " C ", decoct twice, first time decocts 3 hours, and second time decocts 2 hours, afterwards with 500 mesh screen extraction medicinal liquids, for subsequent use;
E, the medicinal liquid extracted in step " D " is added conventional debugger agent, PH is adjusted to by the thick shape of Concentration Modulation 1.4 after 4.5, leaves standstill 12 hours, for subsequent use;
F, step " E " is left standstill the thick shape medicament after 12 hours make pill, packaging completes.
The using method of the department of obstetrics and gynecology medicine of product treatment postpartum depression of the present invention: adopt oral, sooner or later respectively once, each one.
experimental example 1:
Experimental subject: 200 objects having a postpartum depression situation.
Experimental technique: 200 patients are divided into two groups, first group of department of obstetrics and gynecology medicine taking other treatment postpartum depression, second group of department of obstetrics and gynecology medicine taking the treatment postpartum depression of product of the present invention.
Experimental result:
From above experimental result, use the department of obstetrics and gynecology medicine of the treatment postpartum depression of product of the present invention, have very high curative effect to postpartum depression, and due to pure Chinese drug preparation, to user without any side effect.
Typical case:
Lin, 36 years old, owing to being lying-in woman advanced in years, occur depression phenomenon puerperal in 2012, it was postpartum depression that doctor is diagnosed as, and treat for Lin opens medicine, after more than four months of taking medicine, the state of an illness does not take a turn for the better; After this situation, Lin changes medicine, starts to take product of the present invention, and through about 3 months take, Lin's state of an illness was clearly better, and checks, substantially fully recover through doctor.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.

Claims (2)

1. treat a department of obstetrics and gynecology medicine for postpartum depression, the department of obstetrics and gynecology medicine of described treatment postpartum depression is made up of following raw material: Stigma Croci, Radix Notoginseng, Radix Angelicae Sinensis (processed with wine), Rhizoma Cyperi (processed with vinegar), vinegar Rhizoma Corydalis, Radix Aucklandiae (Radix Vladimiriae), raw peach kernel, prepared RHIZOMA CHUAN XIONG with yellow rice wine, process Radix Bupleuri, Radix Sophorae Flavescentis, Fructus Cnidii, Cortex Phellodendri, Herba Fici Simplicissimae, Herba Leonuri, Folium Artemisiae Argyi, Pericarpium Zanthoxyli, the Radix Stemonae, Herba Corydalis Bungeanae, Radix Et Rhizoma Rhei, Caulis Sargentodoxae, Formica fusca grass, the Fructus Kochiae, dried Alumen, Rhizoma Atractylodis, Semen Coicis, Radix Ginseng, Rhizoma Dioscoreae, Semen euryales, Radix Dipsaci, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Concha Ostreae, cotton, Spina Gleditsiae, the Radix Astragali, Borneolum Syntheticum, Herba Patriniae and Herba Taraxaci, described raw material comprises following parts by weight proportioning: Stigma Croci 30g, Radix Notoginseng 20g, Radix Angelicae Sinensis (processed with wine) 45g, Rhizoma Cyperi (processed with vinegar) 30g, vinegar Rhizoma Corydalis 25g, Radix Aucklandiae (Radix Vladimiriae) 25g, raw peach kernel 30g, prepared RHIZOMA CHUAN XIONG with yellow rice wine 50g, process Radix Bupleuri 25g, Radix Sophorae Flavescentis 40g, Fructus Cnidii 20g, Cortex Phellodendri 15g, Herba Fici Simplicissimae 25g, Herba Leonuri 30g, Folium Artemisiae Argyi 10g, Pericarpium Zanthoxyli 20g, Radix Stemonae 15g, Herba Corydalis Bungeanae 35g, Radix Et Rhizoma Rhei 20g, Caulis Sargentodoxae 30g, Formica fusca grass 45g, Fructus Kochiae 20g, dried Alumen 10g, Rhizoma Atractylodis 15g, Semen Coicis 30g, Radix Ginseng 15g, Rhizoma Dioscoreae 20g, Semen euryales 12g, Radix Dipsaci 10g, Rhizoma Atractylodis Macrocephalae 7g, Radix Glycyrrhizae 15g, Concha Ostreae 10g, the cotton 20g in ground, Spina Gleditsiae 30g, Radix Astragali 35g, Borneolum Syntheticum 10g, Herba Patriniae 20g and Herba Taraxaci 20g.
2. a preparation method for the department of obstetrics and gynecology medicine for the treatment of postpartum depression as claimed in claim 1, is characterized in that: comprise the following steps:
A, cut off by Radix Ginseng 15g, adding distil water, the water yield there was not medicine 5 centimetres, with slow fire boiling after 6 hours, used 300 mesh screen, extracted medicinal liquid, for subsequent use;
B, by Radix Angelicae Sinensis (processed with wine) 45g, vinegar Rhizoma Corydalis 25g, raw peach kernel 30g, prepared RHIZOMA CHUAN XIONG with yellow rice wine 50g and process Radix Bupleuri 25g and put into the medicinal liquid that step " A " extracts, soak 4 hours, take out afterwards, for subsequent use;
C, by Stigma Croci 30g, Radix Notoginseng 20g, Rhizoma Cyperi (processed with vinegar) 30g, Radix Aucklandiae (Radix Vladimiriae) 25g, Radix Sophorae Flavescentis 40g, Fructus Cnidii 20g, Cortex Phellodendri 15g, Herba Fici Simplicissimae 25g, Herba Leonuri 30g, Folium Artemisiae Argyi 10g, Pericarpium Zanthoxyli 20g, Radix Stemonae 15g, Herba Corydalis Bungeanae 35g, Radix Et Rhizoma Rhei 20g, Caulis Sargentodoxae 30g, Formica fusca grass 45g, Fructus Kochiae 20g, dried Alumen 10g, Rhizoma Atractylodis 15g, Semen Coicis 30g, Rhizoma Dioscoreae 20g, Semen euryales 12g, Radix Dipsaci 10g, Rhizoma Atractylodis Macrocephalae 7g, Radix Glycyrrhizae 15g, Concha Ostreae 10g, the cotton 20g in ground, Spina Gleditsiae 30g, Radix Astragali 35g, Borneolum Syntheticum 10g, Herba Patriniae 20g and Herba Taraxaci 20g decocts with water 3 times, the water yield was advisable there not to be powder, decocting time is 5 hours for the first time, second time decocting time is 3 hours, decocting time is 2 hours for the third time, 18 hours are left standstill after decocting, use 500 mesh screen, extraction medicinal liquid is for subsequent use,
D, step " B " is soaked after the medical material that extracts add in the medicinal liquid that extracts in step " C ", decoct twice, first time decocts 3 hours, and second time decocts 2 hours, afterwards with 500 mesh screen extraction medicinal liquids, for subsequent use;
E, the medicinal liquid extracted in step " D " is added conventional debugger agent, PH is adjusted to by the thick shape of Concentration Modulation 1.4 after 4.5, leaves standstill 12 hours, for subsequent use;
F, step " E " is left standstill the thick shape medicament after 12 hours make pill, packaging completes.
CN201410530380.XA 2014-10-10 2014-10-10 Obstetrics and gynecology drug for treating postnatal depression and production method thereof Pending CN104225407A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104623460A (en) * 2015-01-05 2015-05-20 崔英 Pharmaceutical composition for nourishingpost stroke depression of lying-in women and preparation method of pharmaceutical composition

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Application publication date: 20141224