CN118161570A - Traditional Chinese medicine composition for treating transmissible gastroenteritis of suckling piglets - Google Patents
Traditional Chinese medicine composition for treating transmissible gastroenteritis of suckling piglets Download PDFInfo
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Abstract
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating Transmissible Gastroenteritis (TGE) of suckling pigs, which effectively solves the problems that in the prior art, the transmissible gastroenteritis is only aimed at the condition of fattening pigs or sows, the mortality rate is very low, and the TGE is not aimed at the condition of the suckling pigs, the condition of the suckling pigs is heavy and the mortality rate is high when the traditional Chinese medicine composition is applied in practice; compared with the prior art, the traditional Chinese medicine composition for treating transmissible gastroenteritis of the suckling piglets comprises radix adenophorae, radix glehniae, dendrobium nobile, rhizoma polygonati officinalis, dogwood and oyster, has the effects of nourishing yin and promoting the production of body fluid, can effectively improve the dehydration and metabolic acidosis of the suckling piglets, achieves the effects of treating TGE and reducing the death rate, is prepared by reasonable process, and is convenient to use.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating transmissible gastroenteritis of suckling piglets.
Background
Transmissible Gastroenteritis (TGE) is a highly contagious intestinal disease caused by transmissible gastroenteritis virus (TGEV) characterized by vomiting, severe diarrhea and high mortality (usually 100%) in piglets of two weeks of age or less. Although pigs of different ages are susceptible to TGEV virus, mortality in pigs over 5 weeks of age is low.
Epidemiology: when a TGEV invades a pig farm, it often quickly infects pigs of all ages, especially in winter, most pigs develop varying degrees of anorexia, vomiting and diarrhea. The piglets are seriously ill, rapidly dehydrated, and the death rate of pigs with ages of 2-3 weeks is very high, but gradually decreases with age. Sows frequently develop morbidity, show anorexia and agalactia, further leading to increased mortality in lactating piglets.
Modern medical treatment TGE method: transmissible Gastroenteritis (TGE) is a highly contagious intestinal disease caused by transmissible gastroenteritis virus (TGEV) characterized by vomiting, severe diarrhea and high mortality in piglets of less than two weeks of age. The piglets are seriously ill, rapidly dehydrated, and the death rate of pigs with ages of 2-3 weeks is very high, and is usually 100%.
Current traditional chinese/middle veterinarian treatment TGE method:
Qu Ziming New Proprietary vet therapeutic university, beijing: china university of agriculture publishers, 1993.12, P288: the treatment method comprises the following steps: clearing heat and detoxicating and stopping dysentery. The prescription comprises the following components: 10 g of coptis chinensis, 12 g of white peony root, 15g of pulsatilla chinensis, 12 g of garden burnet root charcoal, 15g of dark plum fruit, 15g of myrobalan, 6g of rheum officinale, 12 g of liquorice and 12 g of plantain seed. Decoct with water (25 kg pig dose). ("Manual for prevention and treatment of swine diseases" in the following words): the disease is a viral disease, and no special effective treatment method exists. The only method is symptomatic treatment, reducing death of the suckling piglets, promoting early recovery, and giving a sufficient amount of clean drinking water containing electrolyte and certain nutrient components every day.
Hu Yuanliang "Zhongveterinarian proved recipe and wonderful use fine edition", beijing: chemical industry Press 2019.6, P140: transmissible gastroenteritis of swine
And (2) a method 1: prescription: 30 g of coptis chinensis, 30 g of dark plum fruit, 15 g of radix isatidis, 15 g of cooked mugwort, 12 g of medicated leaven, 10g of glabrous greenbrier rhizome, 10g of myrobalan and 30 g of liquorice. Efficacy: clear away heat and toxic materials, dry dampness and stop diarrhea. (Xu Guyu Anhui agronomic advisory, 2016,8)
And (2) the method comprises the following steps: prescription: 100 g of coptis chinensis, 100 g of scutellaria baicalensis, 300 g of radix isatidis, 700 g of phellodendron amurense and 300 g of radix rehmanniae. Efficacy: clear heat and dry dampness, cool blood and detoxify. (Dong Juncheng, china pig industry, 2008.2)
And (3) the following steps: prescription: 100 g of coptis chinensis, 100 g of phellodendron bark, 100 g of ash bark, 100 g of magnolia bark, 200 g of pulsatilla chinensis, 150 g of green tangerine peel, 200 g of hawthorn, 150 g of radish seed, 150 g of wrinkled gianthyssop, 100 g of garden burnet (stir-baked charcoal), 150 g of hairyvein agrimony, 100 g of bighead atractylodes rhizome, 150 g of myrobalan and 50 g of liquorice. Efficacy: clear heat and dry dampness, invigorate spleen and check diarrhea. (Zhao Yingzhen, journal of Chinese veterinary medicine, 2006.6)
The current therapeutic or prescription efficacy of traditional Chinese medicine/veterinarian treatment TGE is: clear away heat and toxic materials, clear away heat and remove dampness, invigorate spleen and check diarrhea. In practice, these formulations are not aimed at the severe and high mortality of suckling pigs, as they are TGEs with low mortality and low mortality for the light illness of fattening pigs or sows; the dehydration and acidosis of the suckling piglets cannot be corrected rapidly, and although some measures such as strengthening feeding management and environmental disinfection are adopted, the ideal effect on the treatment of the TGE of the suckling piglets cannot be obtained.
At present, no effective drug treatment is specially aimed at the TGE of the suckling piglets and reduces the high mortality rate after the TGE of the suckling piglets, so that a drug is urgently needed, the TGE of the suckling piglets can be treated, and the great difficulty in pig raising production is solved.
Disclosure of Invention
Therefore, the invention provides a traditional Chinese medicine composition for treating transmissible gastroenteritis of piglets, which effectively relieves body dehydration and acidosis, and effectively treats TGE of the piglets, thereby reducing mortality.
The invention provides a traditional Chinese medicine composition for treating transmissible gastroenteritis of suckling piglets, which comprises the following components: radix Adenophorae, radix Glehniae, herba Dendrobii, rhizoma Polygonati Odorati, corni fructus, and Concha Ostreae.
Further, the composition comprises the following components in parts by weight: 5-15 parts of radix adenophorae, 5-15 parts of radix glehniae, 5-15 parts of dendrobium, 5-15 parts of radix polygonati officinalis, 5-15 parts of dogwood and 10-30 parts of oyster.
Further, the composition comprises the following components in parts by weight: 10 parts of radix adenophorae, 10 parts of radix glehniae, 10 parts of dendrobium, 10 parts of radix polygonati officinalis, 10 parts of dogwood and 20 parts of oyster.
Further, the preparation method of the traditional Chinese medicine oral liquid for treating the transmissible gastroenteritis of the suckling piglets is characterized by comprising the following steps:
S1, weighing raw materials according to a formula, cracking oyster, and soaking in water for 1 hour;
s2, mixing the raw materials of the adenophora root, the coastal glehnia root, the dendrobium, the fragrant solomonseal rhizome and the dogwood together, and adding water to soak for 1 hour;
s3, decocting oyster for 2 hours, adding other 5 raw materials, decocting for 1 hour, and filtering to obtain a first stock solution;
s4, decocting the residues for 40 minutes, and filtering to obtain a second stock solution;
S5, combining the first stock solution and the second stock solution, concentrating the filtrate to a relative density of 1.1-1.2 (90 ℃), adding ethanol, refrigerating, standing, and filtering to obtain a third stock solution;
s6, recovering ethanol from the third stock solution filtrate, adding water, filling, and sterilizing to obtain the product.
Further, the ethanol content is 65% -75% in the step S5 of the preparation method of the traditional Chinese medicine oral liquid according to claim 4, and the refrigerating and standing time is 48 hours.
Further, in the step S5 of the preparation method of the traditional Chinese medicine oral liquid, the filtrate is concentrated to have the relative density of 1.17 (90 ℃).
Further, the ratio of the third stock solution filtrate to the water in the step S6 is 4:1.
Further, a preparation method of traditional Chinese medicine granules of a traditional Chinese medicine composition for treating transmissible gastroenteritis of piglets comprises the following steps:
S1: weighing raw materials according to the formula, cracking oyster, adding water to soak for 1 hour;
s2, mixing the raw materials of the adenophora root, the coastal glehnia root, the dendrobium, the fragrant solomonseal rhizome and the dogwood together, and adding water to soak for 1 hour;
s3, decocting oyster for 2 hours, adding other 5 raw materials, decocting for 1 hour, and filtering to obtain a first stock solution;
s4, decocting the residues for 40 minutes, and filtering to obtain a second stock solution;
s5, combining the first stock solution and the second stock solution, concentrating the filtrate to a relative density of 1.30-1.33 (20 ℃), and obtaining clear paste;
S6, adding sugar and dextrin into the clear paste to prepare granules, and drying to obtain the finished product.
Further, in the preparation method S6, the proportion of the clear paste, sugar and dextrin is 1:2.5:1.
Further, the traditional Chinese medicine composition is in any one of a traditional Chinese medicine oral liquid, a traditional Chinese medicine granule, a traditional Chinese medicine fluid extract, a tablet and a capsule.
Compared with the prior art, the traditional Chinese medicine composition for treating transmissible gastroenteritis of suckling piglets is prepared from a plurality of traditional Chinese medicines serving as raw materials, including radix adenophorae, radix glehniae, dendrobium nobile, rhizoma polygonati officinalis, dogwood and oyster by reasonable process processing, is convenient to use, and can effectively relieve body dehydration and acidosis, effectively treat TGE of suckling piglets and further reduce death rate.
Detailed Description
In order that the objects and advantages of the invention will become more apparent, the invention will be further described with reference to the following examples; it should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
It should be understood by those skilled in the art that these embodiments are merely for explaining the technical principles of the present invention, and are not intended to limit the scope of the present invention.
It should be noted that, in the description of the present invention, terms such as "upper," "lower," "left," "right," "inner," "outer," and the like indicate directions or positional relationships, and are based on the directions or positional relationships shown in the description, which are merely for convenience of description, but do not indicate or imply that the apparatus or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the invention.
Furthermore, it should be noted that, in the description of the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art according to the specific circumstances.
A traditional Chinese medicine composition for treating transmissible gastroenteritis of suckling piglets comprises the following raw material components:
10 parts of radix adenophorae, 10 parts of radix glehniae, 10 parts of dendrobium, 10 parts of radix polygonati officinalis, 10 parts of dogwood and 20 parts of oyster.
The effects of the raw materials in the invention are as follows:
Radix Adenophorae: the product is dry root of radix Adenophorae or radix Adenophorae of Campanulaceae, is picked up in spring and autumn, fibrous root is removed, crude skin is scraped off when the product is fresh, the product is cleaned, dried, sweet in taste and slightly cold, and the product [ enters channels ] enters lung and stomach channels, and the following raw materials have the main effects, application and usage:
Efficacy: nourishing yin, clearing lung-heat, benefiting stomach, promoting fluid production, reducing phlegm and tonifying qi;
the application is as follows: can be used for treating cough due to lung heat, cough due to yin deficiency, dry cough, phlegm, stomach yin deficiency, anorexia, emesis, qi and yin deficiency, and dysphoria with smothery sensation.
The dosage of the medicine is 9-15g of decoction for oral administration.
Radix glehniae: digging root of Umbelliferae plant coralloides for 7-8 months or 9 months, removing upper stem and fibrous root, cleaning soil, scalding in boiled water, peeling, sun drying or oven drying, and flavoring; cool nature, [ Guijing ] Guifei; stomach meridian. The following main effects, uses and usage amounts of the raw materials are as follows:
efficacy: nourishing yin and clearing lung-heat; stomach benefiting and body fluid production promoting;
The application is as follows: can be used for treating dry cough due to lung dryness, cough due to asthenia, blood deficiency due to stomach yin, and dry wound;
The usage amount is as follows: by oral administration, decocting 5-10g or making into pill, powder or unguent.
Dendrobe: the dendrobium nobile stem is a dendrobium nobile or stems of various plants of the same genus of the dendrobium nobile, and can be harvested all year round, but the quality of a harvester after autumn is good; when fresh is preserved after picking, the fresh dendrobium is cultivated in fine sand stones in spring and autumn, the fine sand stones are placed in a shade and wet place, the roots are kept moist by frequent watering, the fresh dendrobium is flatly placed in a bamboo basket in winter, the cattail bag is covered, but air circulation is noted, and the dried dendrobium is usually obtained by cutting fresh dendrobium stem to remove fibrous roots, cleaning, sun drying or drying; scalding with boiled water in Guangxi region, rubbing while sun drying (or baking) until all are dried; dendrobium otoring: during processing, fresh dendrobium nobile with the length of about 4 cm is picked up, partial fibrous roots are trimmed, cleaned and dried, then the dendrobium nobile is put into an iron pan, evenly fried to be soft, the thin film leaf sheath is rubbed off while the dendrobium nobile is still hot, the dendrobium nobile is put into a ventilated place, the dendrobium nobile is put into a lead skin tray with a thin eye after two days, and then the dendrobium nobile is slightly heated by proper light fire at a place which is about one ruler from the tray, and is bent into a spiral shape or a spring shape by hands, and then the dendrobium nobile is dried again, and the steps are repeated for 2 to 3 times until the dendrobium nobile is dried. Sweet in taste; slightly cold, enter meridians of stomach, lung and kidney. The following main effects, uses, usage amounts and notes of the raw material medicine are as follows:
Efficacy: promoting fluid production and benefiting stomach; nourishing yin and clearing heat; lung moistening and kidney tonifying; improving eyesight and strengthening waist;
the application is as follows: the body fluid is damaged by the main heat; dry mouth and polydipsia; stomach-yin deficiency; pain in the stomach, retching; dry cough with lung dryness; the deficiency heat does not return; dark eyes due to yin injury; weak waist and knee;
The usage amount is as follows: oral administration: decocting 6-15g, and doubling fresh; or making into pill or powder; or decocting the paste. The fresh dendrobium has strong heat clearing and fluid generating capacity and is suitable for people with heat and fluid injury; the dry dendrobium is suitable for patients with stomach deficiency and heat injury;
Notice that: patients with early stage damp-heat disease with yin not wounded, damp-warm disease with damp-dryness not being transformed, and patients with deficiency-cold in spleen and stomach are prohibited from taking.
Polygonatum odoratum (L.) Ohwi: the product is prepared from dried rhizome of Polygonatum odoratum of Liliaceae by digging in autumn, removing fibrous root, cleaning, sun drying to soft, repeatedly kneading, sun drying until no hard core exists, and sun drying; or steaming, kneading to translucence, and sun drying. Sweet in nature and slightly cold in nature. The meridian entered is entered into lung and stomach meridians. The following main effects, uses and usage amounts of the raw materials are as follows:
Efficacy: nourishing yin, moistening dryness, promoting salivation and quenching thirst;
the application is as follows: can be used for treating lung and stomach yin injury, dryness-heat cough, dry throat, thirst, and internal heat diabetes;
the usage amount is as follows: 6-12 g.
Fructus Corni: the product is prepared from dried ripe pulp of Corni fructus of Cornaceae, collecting fruit when the pericarp of autumn and winter turns red, baking with slow fire or scalding in boiling water, removing kernel in time, and drying. Sour and astringent in nature and slightly warm. [ Gui Jing ] enters liver and kidney meridians. The following main effects, uses and usage amounts of the raw materials are as follows:
efficacy: tonifying liver and kidney, inducing astringency to arrest spontaneous emission;
The application is as follows: can be used for treating giddiness, tinnitus, soreness of waist and knees, sexual impotence, spermatorrhea, enuresis, frequent urination, metrorrhagia, leukorrhagia, excessive sweat, deficiency, and internal heat diabetes;
the usage amount is as follows: 6-12 g.
Oyster: the product is shell of oyster, crassostrea gigas or crassostrea gigas of oyster family, and can be used for catching, removing meat, cleaning, and sun drying; salty in nature and slightly cold in nature, enter meridians and liver, gallbladder and kidney meridians. The following main effects, uses and usage amounts of the raw materials are as follows:
efficacy: heavy weight tranquillization, yang suppressing, yin nourishing, hardness softening and resolving;
The application is as follows: can be used for treating palpitation, insomnia, dizziness, tinnitus, scrofula, phlegm nodule, abdominal mass, and acid regurgitation, and for treating spontaneous perspiration, night sweat, spermatorrhea, metrorrhagia, leukorrhagia, gastralgia, and acid regurgitation.
The usage amount is as follows: 9-30 g, and decocting first.
Example 1
A traditional Chinese medicine composition in the form of a traditional Chinese medicine oral liquid for treating transmissible gastroenteritis of suckling piglets comprises the following raw material components in parts by weight: 140g of radix adenophorae, 140g of radix glehniae, 140g of dendrobium, 140g of radix polygonati officinalis, 140g of dogwood and 300g of oyster.
A method of preparing a pharmaceutical combination of example 1 comprising the steps of:
S1, weighing raw materials according to a formula, firstly cracking oyster, and independently adding water to soak for 1 hour;
S2, mixing the raw materials of the adenophora root, the coastal glehnia root, the dendrobium, the fragrant solomonseal rhizome and the dogwood together, and adding water to soak for 1 hour;
s3, decocting oyster for 2 hours, adding other 5 raw materials, decocting for 1 hour, and filtering to obtain a first stock solution;
s4, decocting the residues for 40 minutes, and filtering to obtain a second stock solution;
S5, combining the first stock solution and the second stock solution, concentrating the filtrate to a relative density of about 1.17 (90 ℃), adding ethanol to ensure that the ethanol content reaches 65-75%, refrigerating and standing for 48 hours, and filtering to obtain a third stock solution;
And S7, recovering ethanol from the filtrate, adding water to adjust the temperature to 1000m l, filling and sterilizing to obtain the product.
Example 2
A traditional Chinese medicine composition of traditional Chinese medicine granules for treating transmissible gastroenteritis of suckling piglets comprises the following raw material components in parts by weight: 140g of radix adenophorae, 140g of radix glehniae, 140g of dendrobium, 140g of radix polygonati officinalis, 140g of dogwood and 300g of oyster.
A method of preparing a pharmaceutical combination of example 2 comprising the steps of:
S1: weighing raw materials according to a formula, firstly cracking oyster, and independently adding water to soak for 1 hour;
S2, mixing the raw materials of the adenophora root, the coastal glehnia root, the dendrobium, the fragrant solomonseal rhizome and the dogwood together, and adding water to soak for 1 hour;
s3, decocting oyster for 2 hours, adding other 5 raw materials, decocting for 1 hour, and filtering to obtain a first stock solution;
s4, decocting the residues for 40 minutes, and filtering to obtain a second stock solution;
s5, combining the first stock solution and the second stock solution, and concentrating the filtrate until the relative density is 1.31 (20 ℃) to obtain 222g of clear paste;
s6, mixing the clear paste, sugar and dextrin according to the weight ratio of 1:2.5:1, granulating and drying.
The performance of the traditional Chinese medicine oral liquid prepared in example 1 was tested by a treatment test.
Test for evaluating efficacy
1. Enhanced feeding management and environmental sanitation
The ventilation and purification of the ambient air inside and outside the farm are well done, and the environment is far away from farms, slaughterhouses and innocent treatment plants, so that the infection condition is reduced; the immunization is carried out according to the recommended immunization program; the pig house, the field, personnel, the access way and other links are sterilized, and the high-efficiency disinfectant is used, so that the environmental viral load is reduced, and the infection intensity is reduced. The feeding management work is well done, and the high-quality fresh feed raw materials are adopted, so that the proper temperature and humidity of the pig house are ensured, and various stresses such as high heat, low temperature, weather mutation, material changing and the like are reduced; enhance biological source control of mosquitoes, flies, mice and the like, and cut off the transmission path of viruses; strengthen the health care of each growth stage and reduce the vertical transmission of sow diseases.
2. Treatment of sick piglets
Taking the traditional Chinese medicine oral liquid, and taking 10ml of the liquid every hour for each suckling piglet until diarrhea and death stop. The control group was intramuscular injected with tylosin 10 mg/kg body weight, 2 times a day until diarrhea stopped and death stopped.
3. Conclusion of the experiment
The conclusion shows that compared with the antibiotics for controlling secondary infection, the invention has better treatment effect and the cure rate of more than 55 percent, and solves the production problem that the Transmissible Gastroenteritis (TGE) mortality rate of the suckling piglet is up to 100 percent in production practice. The traditional Chinese medicine composition provides a medicine which is high in efficiency, low in cost, simple, convenient, safe and free of medicine residues for treating Transmissible Gastroenteritis (TGE) of piglets, and has a broad market prospect.
4. Results of treatment experiments
By researching the knowledge of modern medicine on the incidence rules of the TGE of the suckling piglets and the discussion of ancient Chinese medicine books on treating diarrhea, dysentery, cholera, acute appendicitis and other diseases, in particular Shan Shujian and other ancient and modern famous medical science critical evidence Jin Jian diarrhea and dysentery volume, shoudou handbook for cholera prevention and cure (6 th edition), liganzhi structure, chinese medicine digestive disease diagnosis and treatment guide, repeatedly exploring the incidence rules of the TGE of the suckling piglets, the etiology and pathogenesis of the TGE of the suckling piglets are obtained, namely, the diarrhea period is short exogenous cold dampness; the main pattern is that the yin is damaged by the diarrhea in the dehydration period, resulting in deficiency of fluid and yin; the return period is that yin deficiency and damp weight, deficiency of both qi and yin, hyperactivity of fire due to yin deficiency, deficiency of body fluid and heat, cold and heat, and deficiency of both yin and yang. The anaplastic phase is a series of critical cases, the illness is serious, and the illness is bad after healing, which belongs to the disease which is not treated. According to the research result of the pathogenesis of the TGE of the suckling piglet, the key of treatment is to take medicine according to the main syndrome prescription aiming at the deficiency of fluid and yin in the dehydration period. Aiming at the key points of deficiency of body fluid and yin in the TGE pathogenesis of the suckling piglets, the application is prepared by adopting reasonable process processing and preparation with the formula of radix adenophorae, radix glehniae, dendrobium, rhizoma polygonati officinalis, dogwood and oyster, is convenient to use, can rapidly correct dehydration and acidosis in clinic, achieves ideal effects on the premise of adopting some matched measures such as strengthening feeding management and environmental disinfection, reduces the death rate, and has wide application prospect.
Thus far, the technical solution of the present invention has been described in connection with the preferred embodiments, but it is easily understood by those skilled in the art that the scope of protection of the present invention is not limited to these specific embodiments. Equivalent modifications and substitutions for related technical features may be made by those skilled in the art without departing from the principles of the present invention, and such modifications and substitutions will be within the scope of the present invention.
The foregoing description is only of the preferred embodiments of the invention and is not intended to limit the invention; various modifications and variations of the present invention will be apparent to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A traditional Chinese medicine composition for treating transmissible gastroenteritis of suckling pigs is characterized by comprising the following components: radix Adenophorae, radix Glehniae, herba Dendrobii, rhizoma Polygonati Odorati, corni fructus, and Concha Ostreae.
2. The traditional Chinese medicine composition for treating transmissible gastroenteritis of piglets, according to claim 1, is characterized by comprising the following components in parts by weight: 5-15 parts of radix adenophorae, 5-15 parts of radix glehniae, 5-15 parts of dendrobium, 5-15 parts of radix polygonati officinalis, 5-15 parts of dogwood and 10-30 parts of oyster.
3. The traditional Chinese medicine composition for treating transmissible gastroenteritis of piglets, according to claim 2, is characterized by comprising the following components in parts by weight: 10 parts of radix adenophorae, 10 parts of radix glehniae, 10 parts of dendrobium, 10 parts of radix polygonati officinalis, 10 parts of dogwood and 20 parts of oyster.
4. A method for preparing a traditional Chinese medicine oral liquid based on the traditional Chinese medicine composition for treating transmissible gastroenteritis of suckling piglets according to any one of claims 1 to 3, which is characterized by comprising the following steps:
S1, weighing raw materials according to a formula, cracking oyster, and soaking in water for 1 hour;
s2, mixing the raw materials of the adenophora root, the coastal glehnia root, the dendrobium, the fragrant solomonseal rhizome and the dogwood together, and adding water to soak for 1 hour;
s3, decocting oyster for 2 hours, adding other 5 raw materials, decocting for 1 hour, and filtering to obtain a first stock solution;
s4, decocting the residues for 40 minutes, and filtering to obtain a second stock solution;
S5, combining the first stock solution and the second stock solution, concentrating the filtrate to a relative density of 1.1-1.2 (90 ℃), adding ethanol, refrigerating, standing, and filtering to obtain a third stock solution;
s6, recovering ethanol from the third stock solution filtrate, adding water, filling, and sterilizing to obtain the product.
5. The method for preparing a Chinese medicinal oral liquid according to claim 4, wherein the ethanol content is 65% -75% in step S5, and the refrigerating and standing time is 48 hours.
6. The method for preparing an oral liquid of Chinese medicine according to claim 4, wherein the filtrate is concentrated to a relative density of 1.17 (90 ℃ C.).
7. The method for preparing the traditional Chinese medicine oral liquid for treating transmissible gastroenteritis of piglets by filling water according to claim 4, wherein the ratio of the third stock solution filtrate to the water in S6 is 4:1.
8. A method for preparing traditional Chinese medicine granules based on the traditional Chinese medicine composition for treating transmissible gastroenteritis of piglets according to any one of claims 1 to 3, which is characterized by comprising the following steps:
S1: weighing raw materials according to the formula, cracking oyster, adding water to soak for 1 hour;
s2, mixing the raw materials of the adenophora root, the coastal glehnia root, the dendrobium, the fragrant solomonseal rhizome and the dogwood together, and adding water to soak for 1 hour;
s3, decocting oyster for 2 hours, adding other 5 raw materials, decocting for 1 hour, and filtering to obtain a first stock solution;
s4, decocting the residues for 40 minutes, and filtering to obtain a second stock solution;
s5, combining the first stock solution and the second stock solution, concentrating the filtrate to a relative density of 1.30-1.33 (20 ℃), and obtaining clear paste;
S6, adding sugar and dextrin into the clear paste to prepare granules, and drying to obtain the finished product.
9. The method for preparing Chinese medicinal granules according to claim 7, wherein the ratio of the fluid extract, the sugar and the dextrin in the step S6 is 1:2.5:1.
10. The traditional Chinese medicine composition for treating transmissible gastroenteritis of piglets according to any one of claims 1 to 3, wherein the dosage form of the traditional Chinese medicine composition is any one of traditional Chinese medicine oral liquid, traditional Chinese medicine granules, traditional Chinese medicine fluid extract, tablets and capsules.
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