CN105362430A - Drug for preventing and curing swine erysipelas, and preparation method thereof - Google Patents

Drug for preventing and curing swine erysipelas, and preparation method thereof Download PDF

Info

Publication number
CN105362430A
CN105362430A CN201510775469.7A CN201510775469A CN105362430A CN 105362430 A CN105362430 A CN 105362430A CN 201510775469 A CN201510775469 A CN 201510775469A CN 105362430 A CN105362430 A CN 105362430A
Authority
CN
China
Prior art keywords
parts
medicine
radix
pig
fedde
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510775469.7A
Other languages
Chinese (zh)
Inventor
任先武
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HENGYANG JINFENG PIG CULTURE SPECIALIZED COOPERATIVES
Original Assignee
HENGYANG JINFENG PIG CULTURE SPECIALIZED COOPERATIVES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HENGYANG JINFENG PIG CULTURE SPECIALIZED COOPERATIVES filed Critical HENGYANG JINFENG PIG CULTURE SPECIALIZED COOPERATIVES
Priority to CN201510775469.7A priority Critical patent/CN105362430A/en
Publication of CN105362430A publication Critical patent/CN105362430A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a drug for preventing and curing swine erysipelas and a preparation method thereof. The drug for preventing and curing swine erysipelas is prepared from, by mass parts, 140 to 165 parts of fructus forsythiae, 320 to 355 parts of folium isatidis, 220 to 260 parts of rhizoma coptidis, 240 to 270 parts of cortex phellodendri, 320 to 360 parts of fructus gardeniae, 220 to 255 parts of radix gentianae, 215 to 250 parts of cortex moutan, 230 to 275 parts of radix et rhizoma rhei, 140 to 165 parts of liquorice root and 225 to 255 parts of root, stem and leaf of Chinese mahonia. None of the raw materials in the drug provided by the invention are incompatible, and the drug can obviously lower the occurrence rate of swine erysipelas, has good preventing and curing effects on swine erysipelas, has no toxic and side effects, is safe to use, and has no harmful drug residue.

Description

Medicine of control pig erysipelas and preparation method thereof
Technical field
The present invention relates to pig drug world, particularly a kind of medicine preventing and treating pig erysipelas and preparation method thereof.
Background technology
Since reform and opening-up, the pig industry of China is developed rapidly.Scale of raising pigs constantly expands, and breeding way, to batch production, intensive future development, meets the market demand of people to Carnis Sus domestica substantially.But swine diseases remains the key factor of harm and the sound development of restriction pig industry.Particularly the harm of some infectious disease more very, as pig erysipelas etc.This disease is anxious hot, the infectious diseases common to human beings and animals of one caused by bacillus rhusiopathiae suis.Its feature main manifestations is the hot rash block-type in acute sepsis and Asia, shows as individually chronic polyarthritis and endocarditis.This disease is widely current in all over the world, and also there is generation in the many areas of China, thus carrys out huge economic loss to industrial belt of raising pigs.Primary disease all can occur but throughout the year at burning hot and rainy seasonal prevalence, especially with feeder pig susceptible the most.Its clinical symptoms can be divided into most acute, acute and chronic type three kinds.Most acute is clinical more rare, performance sudden onset, sudden death, mortality rate is often 100%, acute presents septicemia change more, clinical common with this kind of, and performance body temperature rises to suddenly 43 DEG C, eat less or go on a hunger strike, stare blankly, instability of gait, happiness lying mat grass, two rubescent, upper eyelid swelling, urinate red constipation, sometimes vomitting.The skin thin location such as in the basal part of the ear, neck side, breast abdomen, stock subsequently, there is kermesinus rash block (being commonly called as diamond-skin disease) irregular, not of uniform size, finger presses rash speckle disappears, hands restores from rash color, and chronic type main manifestations is extremities joint swelling, be off one's feed, walks lamely, cough, hair unrest, day by day become thin.
The medicine preventing and treating pig erysipelas disclosed in prior art mainly contains vaccine, Western medicine and herbal medicine three major types, although three all has prevention effect in various degree, also there is such or such technical problem.As though domestic swine erysipelas vaccine has good prevention curative effect, but find in practice, some person of raising pigs at immune programme for children, inoculation time, there are problems and cause the undesirable even immuning failure of immune effect in the aspects such as dosage of inoculation, What is more does not do immunity and cause primary disease to occur; Western medicine such as antibiotics (penicillin, streptomycin, tetracycline, oxytetracycline etc.), sulfa drugs etc. all have good prevention effect, but, along with prolonged application for many years, even abuse abuse, its curative effect reduces year by year, and consumption then increases year by year, and the continuous formation of endurance strain has been undisputable fact, and there is the residual hidden danger of potential medicine, charcuterie is constituted a threat to safely; Though other commercially available herbal medicine is if erysipelas health, erysipelas spirit etc. are without the drawback of above-mentioned Western medicine, such as because formula is not rigorous, curative effect is not good enough, and delayed the absorption rate of sick pig to effective ingredient, prevention effect is also unsatisfactory.Therefore, the necessary medicine to control swine erysipelas carries out technological innovation.
Summary of the invention
An object of the present invention be overcome prior art above-mentioned deficiency and a kind of medicine preventing and treating pig erysipelas is provided, in medicine of the present invention there is not incompatibility in each material combination, obviously can reduce the incidence rate of pig erysipelas, good preventive and therapeutic action is had to pig erysipelas, and have no side effect, use safety, remains without hazardous drugs.
Another object of the present invention is to provide a kind of preparation method of said medicine, and its technique is simple, and its crude drug is common, cheap.
Technical scheme of the present invention is: a kind of medicine preventing and treating pig erysipelas, and it is made up of the crude drug of following masses part proportioning: Fructus Forsythiae 140-165 part, Folium Isatidis 320-355 part, Rhizoma Coptidis 220-260 part, Cortex Phellodendri 240-270 part, Fructus Gardeniae 320-360 part, Radix Gentianae 220-255 part, Cortex Moutan 215-250 part, Radix Et Rhizoma Rhei 230-275 part, Radix Glycyrrhizae 140-165 part, Mahonia fortunei (Lindl.) Fedde 225-255 part.
Its further preferred mass part proportioning is: Fructus Forsythiae 145-165 part, Folium Isatidis 325-355 part, Rhizoma Coptidis 220-255 part, Cortex Phellodendri 250-270 part, Fructus Gardeniae 320-355 part, Radix Gentianae 220-250 part, Cortex Moutan 220-250 part, Radix Et Rhizoma Rhei 235-275 part, Radix Glycyrrhizae 140-160 part, Mahonia fortunei (Lindl.) Fedde 230-255 part.
Its further preferred mass part proportioning is: Fructus Forsythiae 150-165 part, Folium Isatidis 330-355 part, Rhizoma Coptidis 230-255 part, Cortex Phellodendri 250-265 part, Fructus Gardeniae 330-355 part, Radix Gentianae 220-245 part, Cortex Moutan 230-250 part, Radix Et Rhizoma Rhei 235-270 part, Radix Glycyrrhizae 140-155 part, Mahonia fortunei (Lindl.) Fedde 230-250 part.
Its further preferred mass part proportioning is: Fructus Forsythiae 150-160 part, Folium Isatidis 330-350 part, Rhizoma Coptidis 230-245 part, Cortex Phellodendri 250-260 part, Fructus Gardeniae 340-355 part, Radix Gentianae 220-240 part, Cortex Moutan 230-245 part, Radix Et Rhizoma Rhei 245-270 part, Radix Glycyrrhizae 140-150 part, Mahonia fortunei (Lindl.) Fedde 240-250 part.
Its further preferred mass part proportioning is: Fructus Forsythiae 150-155 part, Folium Isatidis 340-350 part, Rhizoma Coptidis 230-240 part, Cortex Phellodendri 255-260 part, Fructus Gardeniae 340-350 part, Radix Gentianae 230-240 part, Cortex Moutan 230-240 part, Radix Et Rhizoma Rhei 250-260 part, Radix Glycyrrhizae 145-150 part, Mahonia fortunei (Lindl.) Fedde 245-250 part.
Its further preferred mass part proportioning is: Fructus Forsythiae 153 parts, Folium Isatidis 350 parts, Rhizoma Coptidis 235 parts, Cortex Phellodendri 260 parts, Fructus Gardeniae 340 parts, Radix Gentianae 235 parts, Cortex Moutan 235 parts, Radix Et Rhizoma Rhei 260 parts, 150 parts, Radix Glycyrrhizae, Mahonia fortunei (Lindl.) Fedde 245 parts.
Another technical scheme of the present invention is: a kind of preparation method of preventing and treating the medicine of pig erysipelas, it mainly comprises the steps:
One, medicine material is taken by proportion by weight;
Two, the raw material pulverizing will claimed, mix homogeneously, obtains the medicine preventing and treating pig erysipelas.
The present invention further another technical scheme is: after step 2 raw material pulverizing, crosses 100-300 mesh sieve.
The present invention further another technical scheme is: after step 2 raw material pulverizing, crosses 150-300 mesh sieve.
The primary symbols that the present invention uses and name resolving as follows:
-: numerical range, such as 1-5 represents 1 to 5.
The primary raw material medicine that the present invention uses is described as follows:
Fructus Forsythiae: machaka, is commonly called as a string gold, is Oleaceae forsythia.Function cures mainly: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Folium Isatidis: [another name] Folium Isatidis (" book on Chinese herbal medicine is through Ji Zhuan "), LANYE, blue dish, blue buttocks leaf.The leaf of [source] cruciferae isatis or branch and leaf.Medical material nature and flavor: bitter, cold.1. " not Lu ": " bitter in the mouth is Great Cold, nontoxic." 2. " property of medicine opinion ": " sweet in the mouth." 3. " detailed outline ": " gas is trembled with fear, and mildly bitter flavor is salty." [return through] enters liver, the heart, stomach warp.1. " book on Chinese herbal medicine must be joined ": " enter foot sun bright, meridian of Hand-SHAO YIN." 2. " book on Chinese herbal medicine is new again ": " enter liver, spleen two warp." 3. " book on Chinese herbal medicine brief points ": " enter sufficient fall the moon, shaoyin channel."。Function cures mainly: heat clearing away, removing toxic substances, removing heat from blood, hemostasis.Control epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spit blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.
Rhizoma Coptidis: another name: taste company, Rhizoma Coptidis, Rhizoma Coptidis, belongs to Ranunculaceae, Coptis herbaceos perennial, heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Cortex Phellodendri: be the dry bark of rutaceae wampee.Practise and claim " Cortex Phellodendri ".After stripping bark, removing rough bark, dries.For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Fructus Gardeniae: another name Yellow Fructus Gardeniae, Fructus Gardeniae, white toad, Flos Gardeniae are the fruits of Maguireothamnus speciosus Fructus Gardeniae.Genus rubia section, Gardenia Ellis, evergreen shrubs; Root, leaf, fruit all can be used as medicine, and have pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, effect of removing pathogenic heat from blood and toxic substance from the body; Effect: clearing away lung-heat to relieve cough, cooling blood for hemostasis, pathogenic fire purging, cures mainly cough due to lung-heat, coughs up phlegm, toxic swelling, controls calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quenches one's thirst, conjunctival congestion, pharyngalgia, and spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swell and ache.Record in " Chinese medicine voluminous dictionary ": Fructus Gardeniae, different name: wood red (" herbal classic "), fresh (" upper woods is composed "), ancient wine vessel (" Chinese book " Meng Kang notes), more Fructus Persicae (" not Lu "), stand (Collective Notes to the Canon of Materia medica), SHANZHIZI (" property of medicine opinion "), Fructus Gardeniae (" Newly Revised Canon of Materia Medica "), little danger (" book on Chinese herbal medicine is original "), yellow sprout (" east, Fujian book on Chinese herbal medicine "), Yellow Fructus Gardeniae (" Jiangsu medical material will "), yellow Cape jasmine, mountain yellow Cape jasmine, Fructus Gardeniae (" Zhejiang medicinal plants will "); For the fruit of Rubiaceae Gardenia Ellis plant Fructus Gardeniae.
Radix Gentianae: another name: Radix Gentianae, careless Radix Gentianae, Eumeces Chinensis gallbladder, Gentianaceae, Gentiana perennial herb, rhizome is flat sleeping or upright, tool majority fibrous root that is sturdy, slightly meat.Branch Dan Sheng, uprightly, yellow green or aubergine, hollow, subcircular, tool bar rib, tool mastoid process on rib, rare smooth.Branch inferior leads film quality, lilac red, scale shape, tip is separated, and middle part becomes tubular to embrace stem with infracommissure; Heat clearing and damp drying eliminating pathogen in the liver is calmed the frightened.Jaundice due to damp-heat; Urine leaching pain; Swelling of the vulva pudendal pruritus; Damp-heat vaginal discharge; The feeling of fullness in the head headache of liver and gall excess-fire; Conjunctival congestion and swelling pain; Deaf ear swells; Hypochondriac pain bitter taste; Calentura convulsion with spasms.
Cortex Moutan: have another name called Cortex Moutan, Chinese medicine name.For the dry root bark of ranunculaceae peony.Originate in the ground such as Anhui, Shandong.Autumn excavates root, and removing radicula, strips root bark, dry.Life is used or is fried and uses.Clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The pathogenic bacteria later stage brimful of tears, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.
Radix Et Rhizoma Rhei: Radix Et Rhizoma Rhei is being collectively referred to as of the perennial plant of multiple Polygonaceae Rheum is also the title of Chinese crude drug.Radix Et Rhizoma Rhei of the present invention refers to todaiwo,rhizoma.Autumn Mo in the stem and leaf withered or secondary spring excavates before germinateing.Removing radicula, scrapes off crust, valve cutting or section, and the dry or convection drying of bunchiness worn by rope, and Chinese herb rhubarb has effects such as attacking stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances.
Radix Glycyrrhizae: " Chinese medicine voluminous dictionary " is recorded: Radix Glycyrrhizae, [different name] Glycyrrhizae, honey sweet (" herbal classic "), honeywort, black root grass (" not Lu "), state's old (Collective Notes to the Canon of Materia medica), well-informed (" account pearl "), Radix Glycyrrhizae (" florilegium "), Herba Hedyotis cantonensis (" medicinal plants in China will "), sweet root (" Chinese medicinal herbal "), rod grass (" Heilungkiang Chinese medicine "); [base is former] is the root and rhizome of pulse family glycyrrhiza genus Radix Glycyrrhizae, Glycyrrhiza glabra L., Glycyrrhiza inflata Bat.; [function cures mainly] and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Process with controlling weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, lung productive cough is coughed; Raw with controlling laryngopharynx swelling and pain, carbuncle pyogenic infections from tumour or sore, infantile carbuncle, and medicine, alimentary toxicosis.Record according to Compendium of Material Medica: Radix Glycyrrhizae, also sweet, the honeywort of name honey, Glycyrrhizae, grass, well-informed, state is old; Abnormal smells from the patient (root) is sweet, flat, nontoxic.
Mahonia fortunei (Lindl.) Fedde: be Berberidaceae Mahonia fortunei (Lindl.) Fedde platymiscium, another name: the large merit contribution of Mahonia fortunei, spire ten, yellow nandina, Mahonia fortunei (Lindl.)Fedde, Ilex pernyi, Radix seu caulis Berberidis Gagnepainii (Radix Berberidis Virgetori), anistree thorn, Radix Berberidis anhweiensis, cat head (Wan Nan is commonly called as, cat thorn leaf), CIHUANQIN.Caulis Mahoniae, Mahonia fortunei (Lindl.) Fedde, mountain Radix Scutellariae, west wind bamboo, Radix Berberidis soulieanae.Heat-clearing and toxic substances removing, detumescence, antidiarrheal diarrhoea, dysentery, icterohepatitis, burn, scald and sore.
When drug use method of the present invention is fed at every turn, every 500 kg diet, take 2500-3000 gram control pig erysipelas medicine, then by this medicine with appropriate water to mixing up, then add in feedstuff, mix all, feed immediately, every day is sooner or later each feeds once, and every pig 1-3 kilogram is added with the feedstuff of medicine at every turn, within 10 days, be a course for the treatment of, a course for the treatment of of this medicine can be fed every 10 days.
In medicine of the present invention there is not incompatibility in each material combination, facts have proved that this medicine obviously can reduce the incidence rate of pig erysipelas, have good preventive and therapeutic action, and have no side effect, use safety to pig erysipelas, remains without hazardous drugs.
In order to be illustrated more clearly in the present invention, enumerate following examples, but it is without any restrictions to scope of invention.
Detailed description of the invention
embodiment 1
Take Fructus Forsythiae 153g, Folium Isatidis 350g, Rhizoma Coptidis 235g, Cortex Phellodendri 260g, Fructus Gardeniae 340g, Radix Gentianae 235g, Cortex Moutan 235g, Radix Et Rhizoma Rhei 260g, Radix Glycyrrhizae 150g, Mahonia fortunei (Lindl.) Fedde 245g, these material compositions are the quality after drying, and are ground into 150-300 order, mix homogeneously with super micron mill, then pack with plastic bag sealing, the medicine of obtained control pig erysipelas.
using method:during each nursing, every 500 kilograms of feedstuffs mixed up, take the medicine of 2465 grams of the present embodiment control pig erysipelas, then by this medicine with appropriate water to mixing up, then add in feedstuff, mix all, feed immediately, every day is sooner or later each feeds once, and every pig 2.5 kilograms is added with the feedstuff of medicine at every turn, within 10 days, be a course for the treatment of, a course for the treatment of of this medicine can be fed every 10 days.
embodiment 2-14, comparative example 1-2
Embodiment 2-12 is except raw material mass mixture ratio is different from embodiment 1, its raw material type and step of preparation process and using method identical with embodiment 1, comparative example 1 eliminates Radix Gentianae on the basis of embodiment 1, comparative example 2 eliminates Mahonia fortunei (Lindl.) Fedde on the basis of embodiment 2, the raw material that embodiment 1-12, comparative example 1-2 use and quality as shown in Table 1 below, table 1 below illustrates embodiment 1-12, raw material that comparative example 1-2 uses and quality.
Table 1
Clinical trial one:
7-8 month in 2014, carry out the clinical trial of control pig erysipelas medicine in cultivation base, Hunan.The medicine of the control pig erysipelas adopting embodiment 1 to obtain, suffers from erysipelas pig by clinical treatment 150, is divided into 2 groups at random, often organize 75, the every 500 kilograms of feedstuffs mixed up of test group, take 2465 grams of control pig erysipelas medicines, every day is sooner or later each feeds once, allows pig free choice feeding.Matched group is the treatment of commercially available herbal medicine erysipelas health, and by specification is treated, and is used in conjunction 10 days.After 10 days, result of the test shows, and test group is compared with matched group, and therapeutic effect significant difference, cure rate and total effective rate are 97.3% and 98.7%, exceed 10.6% and 8.0% respectively than matched group.Test group pig is after curing, and development condition is good, without rebound phenomenon; And after the healing of matched group pig, indivedual pig still occurs repeatedly.
Clinical trial two:
On the pig farm that epidemic situation occurs, the piglet that 300 health do not fallen ill is divided into 15 groups at random, and often organize 20, wherein 12 groups is chemoprophylaxis group, 2 groups is comparative example group, feed respectively the feedstuff that described in embodiment 1-12, comparative example 1-2, medicine is made into, the every 500 kilograms of feedstuffs mixed up of test group, take 2465 grams of control pig erysipelas medicines, the every day of each nursing sooner or later once, allow pig free choice feeding, another group is matched group, feeds and does not add the identical feedstuff of medicine.15 groups of other measures of piglet all normally to be sterilized immune programme for children by pig farm.Within 10 days, be a course for the treatment of, fed again a course for the treatment of of this medicine every 10 days.After one month, the results are shown in Table 2.
Table 2
Result shows: the sickness rate of chemoprophylaxis group pig erysipelas is than comparative example and low many of matched group, daily gain comparatively comparative example and matched group increases obviously, and the medicine group morbidity spirit of pig, appetite are all better than comparative example and matched group, illness symptom also comparatively comparative example and matched group light.
The present invention is not limited to the medicine as control pig erysipelas, as long as the composition of raw materials medicine identical or equivalent with the present invention just drops within protection scope of the present invention.The raw material of the medicine same recipe with control pig erysipelas of the present invention is made any one Chinese medicine preparation also drop within protection scope of the present invention, as long as the medicine that namely composition of raw materials is identical with the present invention just drops within protection scope of the present invention.

Claims (9)

1. prevent and treat a medicine for pig erysipelas, it is characterized in that being made up of the crude drug of following masses part proportioning: Fructus Forsythiae 140-165 part, Folium Isatidis 320-355 part, Rhizoma Coptidis 220-260 part, Cortex Phellodendri 240-270 part, Fructus Gardeniae 320-360 part, Radix Gentianae 220-255 part, Cortex Moutan 215-250 part, Radix Et Rhizoma Rhei 230-275 part, Radix Glycyrrhizae 140-165 part, Mahonia fortunei (Lindl.) Fedde 225-255 part.
2. prevent and treat the medicine of pig erysipelas according to claim 1, it is characterized in that Fructus Forsythiae 145-165 part, Folium Isatidis 325-355 part, Rhizoma Coptidis 220-255 part, Cortex Phellodendri 250-270 part, Fructus Gardeniae 320-355 part, Radix Gentianae 220-250 part, Cortex Moutan 220-250 part, Radix Et Rhizoma Rhei 235-275 part, Radix Glycyrrhizae 140-160 part, Mahonia fortunei (Lindl.) Fedde 230-255 part.
3. prevent and treat the medicine of pig erysipelas according to claim 1, it is characterized in that Fructus Forsythiae 150-165 part, Folium Isatidis 330-355 part, Rhizoma Coptidis 230-255 part, Cortex Phellodendri 250-265 part, Fructus Gardeniae 330-355 part, Radix Gentianae 220-245 part, Cortex Moutan 230-250 part, Radix Et Rhizoma Rhei 235-270 part, Radix Glycyrrhizae 140-155 part, Mahonia fortunei (Lindl.) Fedde 230-250 part.
4. prevent and treat the medicine of pig erysipelas according to claim 1, it is characterized in that Fructus Forsythiae 150-160 part, Folium Isatidis 330-350 part, Rhizoma Coptidis 230-245 part, Cortex Phellodendri 250-260 part, Fructus Gardeniae 340-355 part, Radix Gentianae 220-240 part, Cortex Moutan 230-245 part, Radix Et Rhizoma Rhei 245-270 part, Radix Glycyrrhizae 140-150 part, Mahonia fortunei (Lindl.) Fedde 240-250 part.
5. prevent and treat the medicine of pig erysipelas according to claim 1, it is characterized in that Fructus Forsythiae 150-155 part, Folium Isatidis 340-350 part, Rhizoma Coptidis 230-240 part, Cortex Phellodendri 255-260 part, Fructus Gardeniae 340-350 part, Radix Gentianae 230-240 part, Cortex Moutan 230-240 part, Radix Et Rhizoma Rhei 250-260 part, Radix Glycyrrhizae 145-150 part, Mahonia fortunei (Lindl.) Fedde 245-250 part.
6. prevent and treat the medicine of pig erysipelas according to claim 1, it is characterized in that Fructus Forsythiae 153 parts, Folium Isatidis 350 parts, Rhizoma Coptidis 235 parts, Cortex Phellodendri 260 parts, Fructus Gardeniae 340 parts, Radix Gentianae 235 parts, Cortex Moutan 235 parts, Radix Et Rhizoma Rhei 260 parts, 150 parts, Radix Glycyrrhizae, Mahonia fortunei (Lindl.) Fedde 245 parts.
7. prevent and treat the preparation method of the medicine of pig erysipelas according to claim 1, it is characterized in that comprising the steps:
One, by proportion by weight weighting raw materials;
Two, the crude drug claimed is pulverized, mix homogeneously, obtain the medicine preventing and treating pig erysipelas.
8. the preparation method of the medicine of described control pig erysipelas according to claim 7, after it is characterized in that step 2 raw material pulverizing, crosses 100-300 mesh sieve.
9. the preparation method of the medicine of described control pig erysipelas according to claim 7, after it is characterized in that step 2 raw material pulverizing, crosses 150-300 mesh sieve.
CN201510775469.7A 2015-11-15 2015-11-15 Drug for preventing and curing swine erysipelas, and preparation method thereof Pending CN105362430A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510775469.7A CN105362430A (en) 2015-11-15 2015-11-15 Drug for preventing and curing swine erysipelas, and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510775469.7A CN105362430A (en) 2015-11-15 2015-11-15 Drug for preventing and curing swine erysipelas, and preparation method thereof

Publications (1)

Publication Number Publication Date
CN105362430A true CN105362430A (en) 2016-03-02

Family

ID=55365384

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510775469.7A Pending CN105362430A (en) 2015-11-15 2015-11-15 Drug for preventing and curing swine erysipelas, and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105362430A (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177081A (en) * 2016-08-24 2016-12-07 四川荣州动物药业有限公司 A kind of detoxication and toxicant eliminating function superfine powder Chinese veterinary medicinal composition and preparation method thereof
CN106421174A (en) * 2016-08-26 2017-02-22 任英明 Veterinary herbal medicine for treating swine erysipelas
CN106491906A (en) * 2016-12-11 2017-03-15 衡阳县轩健农牧发展有限公司 A kind of Chinese medicine composition of preventing and treating pig erysipelas and preparation method thereof
CN106491907A (en) * 2016-12-11 2017-03-15 衡阳县轩健农牧发展有限公司 Medicine of preventing and treating pig erysipelas and preparation method thereof
CN108310239A (en) * 2018-03-22 2018-07-24 霍邱县小根生猪养殖专业合作社 A kind of Chinese medicine composition of prevention brickpox
CN109125470A (en) * 2018-11-02 2019-01-04 衡阳市武顺循环农牧绿色生态科技有限公司 A kind of drug and preparation method thereof for preventing and treating duck virus hepatitis
CN109125468A (en) * 2018-11-01 2019-01-04 衡阳市武顺循环农牧绿色生态科技有限公司 A kind of drug and preparation method thereof for preventing and treating brickpox

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102961515A (en) * 2012-11-22 2013-03-13 青岛绿曼生物工程有限公司 Compound propolis combination for treating swine erysipelas and preparation method of combination

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102961515A (en) * 2012-11-22 2013-03-13 青岛绿曼生物工程有限公司 Compound propolis combination for treating swine erysipelas and preparation method of combination

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
新疆部队后勤部卫生部编: "《家畜常见病防治手册》", 31 March 1971, 新疆人民出版社 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177081A (en) * 2016-08-24 2016-12-07 四川荣州动物药业有限公司 A kind of detoxication and toxicant eliminating function superfine powder Chinese veterinary medicinal composition and preparation method thereof
CN106421174A (en) * 2016-08-26 2017-02-22 任英明 Veterinary herbal medicine for treating swine erysipelas
CN106491906A (en) * 2016-12-11 2017-03-15 衡阳县轩健农牧发展有限公司 A kind of Chinese medicine composition of preventing and treating pig erysipelas and preparation method thereof
CN106491907A (en) * 2016-12-11 2017-03-15 衡阳县轩健农牧发展有限公司 Medicine of preventing and treating pig erysipelas and preparation method thereof
CN108310239A (en) * 2018-03-22 2018-07-24 霍邱县小根生猪养殖专业合作社 A kind of Chinese medicine composition of prevention brickpox
CN109125468A (en) * 2018-11-01 2019-01-04 衡阳市武顺循环农牧绿色生态科技有限公司 A kind of drug and preparation method thereof for preventing and treating brickpox
CN109125470A (en) * 2018-11-02 2019-01-04 衡阳市武顺循环农牧绿色生态科技有限公司 A kind of drug and preparation method thereof for preventing and treating duck virus hepatitis

Similar Documents

Publication Publication Date Title
CN105362430A (en) Drug for preventing and curing swine erysipelas, and preparation method thereof
CN102078419B (en) Medicament for preventing and treating porcine reproductive and respiratory syndrome (PRRS) and preparation method thereof
CN105232704A (en) Medicine for preventing and treating bovine rumen flatulence and preparation method thereof
CN105287841A (en) Drug for preventing swine erysipelas and preparation method thereof
CN104127551B (en) A kind of heat-clearing and toxic substances removing, antiviral veterinary Chinese medicinal composition and preparation method and application
CN103495007A (en) Traditional Chinese medicine microecologics preparation for preventing and treating pullorum disease and preparation method of microecologics preparation
CN105994986A (en) Traditional Chinese medicine preparation for preventing and treating parasitic diseases of goats and preparation method of traditional Chinese medicine preparation
CN105233116A (en) Traditional Chinese medicine composition for preventing and controlling respiratory tract infection of chicken and preparation method thereof
CN104306679A (en) Chinese herb agentia for treating epidemic cerebrospinal meningitis and preparation method thereof
CN104096007A (en) Goat stress prevention and control traditional Chinese medicine composition and preparation method thereof
CN104940404A (en) Preparation for preventing pullorum disease and preparation method
CN106474230A (en) Chinese medicine composition of preventing and treating Rana grylia torticollis disease and preparation method thereof
CN104887806A (en) Traditional Chinese medicine preparation for treating poultry dysentery
CN104548013A (en) Traditional Chinese medicine for treating facial paralysis and preparation method of traditional Chinese medicine
CN104147399A (en) Pharmaceutical preparation for swine fever
CN106361902A (en) Traditional Chinese medicine composition for preventing and treating livestock diarrhea and preparation method thereof
CN103239673B (en) Traditional Chinese medicine composition for preventing and curing sudden death syndrome of cow
CN109125468A (en) A kind of drug and preparation method thereof for preventing and treating brickpox
CN102743508B (en) Compound propolis composition for treating avian infectious laryngotracheitis and preparation method thereof
CN105311186A (en) Medicine for preventing and treating bovine tumor gaseous distention and preparation method thereof
CN106310226A (en) Chinese herbal medicine compound preparation for preventing and treating piglet dysentery and preparation method thereof
CN102091227B (en) Chinese medicinal preparation for treating swelling and pain in throat and preparation method thereof
CN105079303A (en) Medicine for preventing and curing Chicken infectious anemia
CN106344876A (en) Traditional Chinese medicine composition for controlling livestock/poultry respiratory diseases and preparation method thereof
CN106107036A (en) A kind of livestock fodder additives with epidemic prevention function

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20160302