CN106310226A - Chinese herbal medicine compound preparation for preventing and treating piglet dysentery and preparation method thereof - Google Patents
Chinese herbal medicine compound preparation for preventing and treating piglet dysentery and preparation method thereof Download PDFInfo
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- CN106310226A CN106310226A CN201610912767.0A CN201610912767A CN106310226A CN 106310226 A CN106310226 A CN 106310226A CN 201610912767 A CN201610912767 A CN 201610912767A CN 106310226 A CN106310226 A CN 106310226A
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- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
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Abstract
The invention discloses a Chinese herbal medicine compound preparation for preventing and treating piglet dysentery. The compound preparation comprises Chinese pulsatilla root, coptis chinensis, scutellaria baicalensis, atractylodes, rhodomyrtus tomentosa hassk, astragalus, potentilla anserine, chloris virgata, geranium wilfordii, vitamin E and EGF. The invention also discloses a preparation method of the Chinese herbal medicine compound preparation. When the Chinese herbal medicine compound preparation is adopted in a large-scale piglet breeding process, the piglet dysentery can be effectively prevented and treated, anti-inflammatory and diarrhea checking effects can be realized, immunity of piglets can be improved, spleen and stomach can be regulated, and occurrence probability of the piglet dysentery is reduced. The Chinese herbal medicine compound preparation disclosed by the invention has the functions of improving the immunity of the piglets, relieving stress, clearing away heat and toxic materials, regulating intestines and stomach, astringing intestines to stop diarrhea as well as drying dampness and strengthening spleen and can be widely applied to practice of prevention and treatment of the piglet dysentery.
Description
Technical field
The invention belongs to veterinary Chinese medicine technical field, be specifically related to a kind of compound Chinese medicinal preparation preventing and treating baby pig diarrhoea and system
Preparation Method.
Background technology
Baby pig diarrhoea is the common frdquently encountered disease affecting pig-breeding, is the major reason causing piglet dead, also causes
The principal element that culture benefit is low.1-3 age in days piglet easily sends out piglet red dysentery clinically；1-7 age in days piglet easily sends out yellow scour of piglet,
I.e. early onset escherichia coli dysentery, morbidity and mortality rate are high, the most all can fall ill, but the winter and early spring with severe cold falls ill
More, to draw yellow loose stool as chief complaint；10-30 age in days piglet easily sends out piglet pujos blancos, caused by Escherichia coli
Suckling pig infectious disease.Piglet discharges milky, yellow green or canescence feces, thickness medicated porridge sample, has unpleasant bad smell；Disconnected
Piglet before and after milk stress be changed by environment and nutrition suddenly, causes piglet dyspepsia, diarrhoea and resistance to decline, Yi Fa
Baby swine paratyphoid etc..Therefore for reducing the incidence rate of baby pig diarrhoea, culture benefit is improved, should be to improve pigling immunity, alleviation
Stress, heat-clearing and toxic substances removing, regulation digestive functions, relieving dysentery with astringents, drying damp and strengthening spleen for principle.
The Chinese medicine compound that the present invention is directed to easily occur the piglet of dysentery to develop is according to instruction of Chinese Medicine theory, low according to immunity
Under, easily there is stress, weakness of the spleen and stomach, dyspepsia, the clinical disease such as have loose bowels, from " improve immunity, alleviate stress, clear
Thermal detoxification, regulation the intestines and stomach, relieving dysentery with astringents, drying damp and strengthening spleen " etc. aspect set about, develop a kind of determined curative effect, safe ready, pair
Act on the compound Chinese medicinal preparation of little, cheap preventing and treating baby pig diarrhoea, can effectively prevent and treat baby pig diarrhoea, also be avoided that excessively
Use the drug residue that chemicals, antibiotic cause.
Summary of the invention
Present invention aims to baby pig diarrhoea is the major reason causing piglet dead, is often sending out of pig-breeding
Epidemic disease, has had a strong impact on the practical problem of culture benefit etc., it is provided that one can improve during large-scale cultivation live pig
Pigling immunity, alleviate stress, heat-clearing and toxic substances removing, regulation the intestines and stomach, removing heat from blood dampness, invigorating spleen and reinforcing stomach, the Chinese medicine compound system of relieving dysentery with astringents
Agent.
The present invention the technical scheme is that for achieving the above object
A kind of compound Chinese medicinal preparation preventing and treating baby pig diarrhoea, it is characterised in that described compound Chinese medicinal preparation includes following component: white
Head father-in-law, Rhizoma Coptidis, Radix Scutellariae, Rhizoma Atractylodis, Radix Rhodomyrti, the Radix Astragali, Radix potentillae anserinae, Radix seu Caulis Embeliae Parviflorae, Herba Erodii, vitamin E, EGF.
Further, consist of the following composition: Radix Pulsatillae 100-400g, Rhizoma Coptidis 50-200g, Radix Scutellariae 75-300g, Rhizoma Atractylodis
75-300g, Radix Rhodomyrti 75-300g, Radix Astragali 50-200g, Radix potentillae anserinae 50-200g, Radix seu Caulis Embeliae Parviflorae 50-200g, Herba Erodii 50-200g, dimension
Raw element E100-400mg, EGF1 × 106-4×106IU。
Further, consist of the following composition: Radix Pulsatillae 150-300g, Rhizoma Coptidis 75-125g, Radix Scutellariae 100-200g, Rhizoma Atractylodis
100-200g, Radix Rhodomyrti 100-200g, Radix Astragali 75-125g, Radix potentillae anserinae 75-125g, Radix seu Caulis Embeliae Parviflorae 75-125g, Herba Erodii 75-125g,
Vitamin e1 50-300mg, EGF1.5 × 106-2.5×106IU。
Further, consist of the following composition: Radix Pulsatillae 200g, Rhizoma Coptidis 100g, Radix Scutellariae 150g, Rhizoma Atractylodis 150g, mountain are harvested
Root 150g, Radix Astragali 100g, Radix potentillae anserinae 100g, Radix seu Caulis Embeliae Parviflorae 100g, Herba Erodii 100g, vitamin E2 00mg, EGF2 × 106IU。
Further, described compound Chinese medicinal preparation is Chinese powder medicine, capsule, oral liquid, granule or tablet.
The invention also discloses the Chinese medicine compound preparation method of above-mentioned preventing and treating baby pig diarrhoea, specifically comprise the following steps that
1) Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Rhizoma Atractylodis, Radix Rhodomyrti, the Radix Astragali, Radix potentillae anserinae, Radix seu Caulis Embeliae Parviflorae, Herba Erodii are added 8-15 times amount soak by water
2-3 time, each 1-2 hour, merge decoction liquor, filter, be evaporated to relative density 1.20 ~ 1.28(50 DEG C), be dried to do
Cream；
2) dried cream powder is broken into fine powder, crosses 100 mesh sieves, add vitamin E, EGF and dextrin, mixing, carry out pelletization treatment subsequently
And be dried, obtain compound particles, then in compound particles, add magnesium stearate, it is thus achieved that capsule 's content, by described glue
Capsule content loading capsule housing i.e. obtains capsule.
Further, in step 1), amount of water is 10 times amount water, and decocting number of times is 3 times, each 1 hour.
Prescription analysis:
The Radix Pulsatillae: Ranunculaceae, Anemone herbaceos perennial, it is avette that length has root stock, blade, calyx bluish violet.In vain
Head father-in-law's root is containing anemoside, it is possible to suppression staphylococcus aureus, bacillus pyocyaneus, dysentery bacterium, bacillus subtilis, typhoid fever bar
The growth of bacterium, Salmonella etc., its antibiotic effective ingredient is Anemonin and protoanemonin, and the Radix Pulsatillae have stronger killing
Fungus effect.Additionally, dermatophytes, yeast, trypanosomicide, Candida albicans etc. are all had by the Radix Pulsatillae and compound recipe thereof such as Radix Pulsatillae Decoction
Inhibitory action.
Rhizoma Coptidis: belong to Ranunculaceae, Coptis herbaceos perennial, containing multiple isoquinoline alkaloid in stem, berberine contains
Measure the highest, and coptisine, 13-methyl-.psi.-coptisine., jateorhizine etc..Rhizoma Coptidis has the strongest antibacterial action, suppresses Staphylococcus aureus
Bacterium, Hemolytic streptococcus, streptococcus pneumoniae, meningococcus, dysentery bacterium, anthrax bacillus etc..Also having antiviral, protozoacide is made
With.In addition Rhizoma Coptidis also has Detoxication, such as antagonism bacteriotoxin, reduces staphylococcus aureus coagulase, hemolysin titer, fall
Low colibacillary virulence etc.；And antiinflammatory, antipyretic effect.
Radix Scutellariae: for Labiatae Scutellaria herbaceos perennial.The root of Radix Scutellariae is used as medicine, bitter in the mouth, cold in nature, have heat clearing and damp drying,
Eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Radix Scutellariae multiple flavone component Han baicalin, baicalin etc., has antibacterial, the work of antiviral
With, to alpha streptococcus, Diplococcus pneumoniae, meningococcus, staphylococcus aureus, diphtheria corynebacterium, tubercule bacillus, dysentery
The multiple coccus such as bacillus and vibrio cholera and bacillus and influenza virus all have inhibitory action.In addition with antiinflammatory, suppression immunity
The effects such as reaction.
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For retention of dampness in middle-JIAO, gastral cavity
Distention and fullness in the abdomen, has loose bowels, edema, and tinea pedis flaccidity is knitted, and rheumatic arthralgia, anemofrigid cold, eyes dusk is puckery.Rhizome contains volatile oil about 5～9%, mainly
Composition is atractylol, hinesol, sagittol etc..Rhizoma Atractylodis can suppress multiple enteropahtogenic microganism to grow, to escherichia coli, intestinal
The pathogen such as scorching Salmonella, staphylococcus aureus, Pseudomonas aeruginosa have suppression and deactivation significantly.
The Radix Astragali: sweet in the mouth, tepor, return lung, spleen, liver, kidney channel.Have enhancing human body immunity function, protect the liver, diuresis, anti-stress, fall
Pressure and wide antibacterial action.
Radix potentillae anserinae is Rosaceae potentilla plants Potentilla anserina L., is used as medicine with tuber, Radix potentillae anserinae calls Herba Herminii, Rhizoma Nelumbinis is spent,
Radix potentillae anserinae, meridian distribution of property and flavor: sweet is flat.Gui Jing: spleen；Stomach warp.Radix potentillae anserinae fills blood, strengthening the spleen and stomach, promoting the production of body fluid to quench thirst, effect of dampness removing, Herba pteridii latiusculi
Fiber crops treat anemia after being ill, malnutrition, insufficiency of the spleen diarrhoea, the effect of rheumatic arthralgia.Herba Erodii: call old stork mouth, crow mouth, pass through
Muscle, always pass through muscle, old tendon Bovis seu Bubali.Source: this product is going up dryly of Niu Er Seedling section plant cattle Seedling, Herba Erodii or Carolina Cranesbill Herb
Part: acrid in the mouth, hardship, property is put down.Return liver,kidney,spleen warp.Function cures mainly dispels the wind, and invigorates blood circulation, heat-clearing and toxic substances removing.Dispelling the wind and dampness pathogens pain, contracture fiber crops
Wood, carbuncle, traumatic injury, enteritis, dysentery." the southern regions of the Yunnan Province book on Chinese herbal medicine ": all wind skin of dispelling is itched.Controlling bones and muscles pain, phlegm-fire flaccidity is soft, brothers' muscle
Contraction, numb, diuresis, rushes down bladder accumulated heat, attacks scattered all pyogenic infections from tumour or sore, move back consumptive disease heat fever, control the diseases such as wind-fire dental caries, varioliform exanthema mange." expensive
State side among the people medicine collection ": controlling traumatic injury, only knife injury is hemorrhage, again can cough-relieving, lung benefiting gas.
Radix Rhodomyrti: call downy rosemyrtle root, when Radix pyri, cutter lotus head, for many years sheet, root of trembling, many days, beer daughter root of trembling, sound of sighing head of trembling.
For myrtaceous of myrtle.Acrid in the mouth；Sweet；Property flat.Function cures mainly regulating QI to relieve pain；Dampness removing antidiarrheal；Removing stasis to stop bleeding；Kidney tonifying
Nourish blood.Cure mainly epigastric pain；Dyspepsia；Vomiting dysentery；Hypochondriac pain jaundice；Abdominal mass；Mass in the abdomen；Metrorrhagia；Impairment caused by overstrain is hemorrhage；Traumatic injury is hindered
Bitterly；Rheumatic arthralgia；Blood deficiency is weak；Lumbago due to renal deficiency；Knee joint is soft；Frequent micturition；Nebulousurine；Edema；Hernia；Carbuncle scrofula；Hemorrhoid；Burn and scald.
Radix seu Caulis Embeliae Parviflorae: popular name wooden club hip careless, big grass, belongs to annual herb plant for grass family Radix seu Caulis Embeliae Parviflorae, for domestic animal high-quality
Food grass.Acrid in the mouth；Bitter；Slightly warm in nature.Function cures mainly expelling wind and removing dampness；Removing toxic substances parasite killing.Main headache due to common cold；Rheumatic arthralgia；Dysentery is suffered from abdominal pain；Hernia
Gas；Tinea pedis；Ulcerative carbuncle toxic swelling；Knife injury.
Vitamin E: be a kind of natural feed antioxidant, is strengthening immunity of livestock, oxidation resistance and prevention not
Pregnant disease, improve livestock and poultry production performance and improve the aspects such as animal meat quality there is important function, being possible to prevent intracellular and cell membrane
Oxidized and destroyed with readily oxidizable substance such as fatty acids, thus protect the complete of cell membrane.Vitamin E also has anti-answering
Swash, antiviral, infection etc. act on.
EGF: i.e. epithelical cell growth factor, has another name called oligopeptide-1, is a kind of active substance in human body, by 53 amino groups
The active polypeptide become, by the tyrosine phosphorylation of stimulation EGFR, reaches to repair hypertrophy cells of superficial layer,
Its maximum feature is to promote the proliferation and differentiation of cell, thus replaces old and feeble and dead cell with newborn cell.EGF has
There are acceleration skin and mucosa wound healing, anti-inflammatory analgesic, prevent effect of ulcer.
In sum, owing to have employed technique scheme, the invention has the beneficial effects as follows:
Use this kind of compound Chinese medicinal preparation can prevent and treat baby pig diarrhoea, antiinflammatory antidiarrheal during large-scale cultivation domestic animal, improve
Piglet resistance, regulation taste, reduction baby pig diarrhoea occurrence probability.This compound Chinese medicinal preparation has raising pigling immunity, delays
Solution stress, heat-clearing and toxic substances removing, regulation the intestines and stomach, relieving dysentery with astringents, drying damp and strengthening spleen function, and can avoid because of excessively use chemicals,
The drug residue that antibiotic causes, can be widely applied in the practice of baby pig diarrhoea.
Detailed description of the invention
Below the technical scheme in the embodiment of the present invention is clearly and completely described.Based on the enforcement in the present invention
Example, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, broadly fall into
The scope of protection of the invention.
Embodiment 1
A kind of Herbal compound capsule agent preventing and treating baby pig diarrhoea, including: Radix Pulsatillae 200g, Rhizoma Coptidis 100g, Radix Scutellariae 150g, Rhizoma Atractylodis
150g, Radix Rhodomyrti 150g, Radix Astragali 100g, Radix potentillae anserinae 100g, Radix seu Caulis Embeliae Parviflorae 100g, Herba Erodii 100g, vitamin E2 00mg, EGF2 ×
106IU。
Its concrete preparation method is as follows:
1) Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Rhizoma Atractylodis, Radix Rhodomyrti, the Radix Astragali, Radix potentillae anserinae, Radix seu Caulis Embeliae Parviflorae, Herba Erodii are added 10 times amount soak by water 3
Secondary, each 1 hour, merge decoction liquor, filter, be evaporated to relative density 1.20 ~ 1.28(50 DEG C), be dried to dry cream；
2) dried cream powder is broken into fine powder, crosses 100 mesh sieves, add vitamin E, EGF and dextrin, mixing, carry out pelletization treatment subsequently
And be dried, obtain compound particles, then in compound particles, add magnesium stearate, it is thus achieved that capsule 's content, by described glue
Capsule content loading capsule housing i.e. obtains capsule.
Embodiment 2
A kind of complex injection of Chinese materia medica preventing and treating baby pig diarrhoea, including:
Radix Pulsatillae 100g, Rhizoma Coptidis 50g, Radix Scutellariae 75g, Rhizoma Atractylodis 75g, Radix Rhodomyrti 75g, Radix Astragali 50g, Radix potentillae anserinae 50g, Radix seu Caulis Embeliae Parviflorae 50g, old
Stork grass 50g, vitamin e1 00mg, EGF1 × 106IU。
Its concrete preparation method is as follows:
1) Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Rhizoma Atractylodis, Radix Rhodomyrti, the Radix Astragali, Radix potentillae anserinae, Radix seu Caulis Embeliae Parviflorae, Herba Erodii are added 12 times amount soak by water 2
Secondary, each 2 hours, merge decoction liquor, filter, be evaporated to relative density 1.20 ~ 1.28(50 DEG C), be dried to dry cream；
2) dried cream powder is broken into fine powder, crosses 100 mesh sieves, add vitamin E, EGF and dextrin, mixing, carry out pelletization treatment subsequently
And be dried, obtain compound particles, then in compound particles, add magnesium stearate, it is thus achieved that capsule 's content, by described glue
Capsule content loading capsule housing i.e. obtains capsule.
Embodiment 3
A kind of Chinese medicine compound powder preventing and treating baby pig diarrhoea, including: Radix Pulsatillae 400g, Rhizoma Coptidis 200g, Radix Scutellariae 300g, Rhizoma Atractylodis
300g, Radix Rhodomyrti 300g, Radix Astragali 200g, Radix potentillae anserinae 200g, Radix seu Caulis Embeliae Parviflorae 200g, Herba Erodii 200g, vitamin E 400mg, EGF4 ×
106IU。
The Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Rhizoma Atractylodis, Radix Rhodomyrti, the Radix Astragali, Radix potentillae anserinae, Radix seu Caulis Embeliae Parviflorae, Herba Erodii are respectively crushed into fine powder,
Cross 80 mesh sieves, add vitamin E and EGF mixing, subpackage, to obtain final product.
Embodiment 4
1, long term toxicity test process
Application Wistar rat (Beijing Vital River Experimental Animals Technology Co., Ltd.'s offer) Experimental agents is set as height,
In, low three dosage, respectively capsule 8g/kg, 4g/kg, 2g/kg of embodiment 1 formula.Separately set a matched group, fill continuously
After stomach is administered 90 days, 180 days and Some Animals drug withdrawal 10 days, observe physiology every on rat, the impact of biochemical indicator.Experiment knot
Fruit shows: increase all without affecting to rat continuous oral 180 days, food-intake and body weight on rat by various dose.To Liver and kidney
Function does not all find overt toxicity effect.Routine blood test, blood biochemistry, urine biochemistry and bone marrow sheet etc. are showed no and significantly affect, respectively
No significant difference is compared with matched group between group.
2, acute toxicity test process:
Application ICR mice (Beijing Vital River Experimental Animals Technology Co., Ltd.'s offer) 40, body weight, at 25-30 gram, is carried out
Acute toxicity testing.Mice is randomly divided into two groups, i.e. matched group, administration group, fasting 12 hours before experiment, then gives as implemented
Chinese medicine capsules suspension (capsule the is dissolved in water acquisition suspension) gavage of the present invention that example 1 prepares, to giving
Median lethal dose(LD 50) (the LD of medicine50) carry out test determination, but do not measure LD50, therefore carried out mtd test.Result:
With Cmax (60%), maximum dosage-feeding (120ml/kg, in a day, part gives for four times) 100g/kg gavage, be equivalent to crude drug amount
60g/kg, none death of mice in seven days, put to death each internal organs of mice anatomic observation and do not find toxic reaction, administration group and matched group
Mice is without any difference.
3, dysentery piglet pharmacodynamics test
Experimental animal: certain age in days left and right, pig farm 20 DLY tri-crossbreeding generation baby pig diarrhoea, clinical condition is lethargy, food
Being intended to depressed, dyspepsia, diarrhoea, feces is water sample shape.Choosing wherein 30 piglets, enter through nosetiology escherichia coli standard serum type
Row slide agglutination test, is diagnosed as escherichia coli.30 piglets that dysentery occurs are divided into 2 groups, often group 15, are respectively celebrating big
Mycin group and middle medicine composite preparation group.Two groups use identical drinking-water, feedstuff and feed mode, and wherein gentamycin group piglet is every
Oral gentamicin, per kilogram of body weight 10mg；Middle medicine composite preparation group piglet every decoction being taken at a draught capsule 1-2 grain, continuous use 5
My god.
Evaluation criterion is according to curing degree after medication: after medication 5 days, dysentery piglet clinical symptom disappearance, spirit appetite
All recover normal；According to significant degree after medication: the clinical symptom reliefs such as diarrhoea, dyspepsia, appetite take a turn for the better, spirit is the most extensive
Multiple.Invalid: the clinical symptoms such as diarrhoea, dyspepsia do not alleviate, in some instances it may even be possible to aggravation trend, lethargy, inappetence occur
Or exhausted, dehydration of becoming thin of giving up.
After medication is treated 5 days, gentamycin group effective head number is 5, several 6 of healing, invalid several 4, cure rate
It is 40.0%, total effective rate 73.33%；Several 4 of effective of middle medicine composite preparation group, several 10 of healing, invalid several 1, control
More rate is 66.67%, cure rate 93.33%.Result of the test shows, middle medicine composite preparation group has good in terms for the treatment of baby pig diarrhoea
Good curative effect.
Claims (7)
1. the compound Chinese medicinal preparation preventing and treating baby pig diarrhoea, it is characterised in that described compound Chinese medicinal preparation includes following component:
The Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Rhizoma Atractylodis, Radix Rhodomyrti, the Radix Astragali, Radix potentillae anserinae, Radix seu Caulis Embeliae Parviflorae, Herba Erodii, vitamin E, EGF.
A kind of compound Chinese medicinal preparation preventing and treating baby pig diarrhoea the most as claimed in claim 1, it is characterised in that described Chinese medicine compound
Preparation includes the composition of following weight portion: Radix Pulsatillae 100-400g, Rhizoma Coptidis 50-200g, Radix Scutellariae 75-300g, Rhizoma Atractylodis 75-300g,
Radix Rhodomyrti 75-300g, Radix Astragali 50-200g, Radix potentillae anserinae 50-200g, Radix seu Caulis Embeliae Parviflorae 50-200g, Herba Erodii 50-200g, vitamin e1 00-
400mg、EGF1×106-4×106IU。
A kind of compound Chinese medicinal preparation preventing and treating baby pig diarrhoea the most as claimed in claim 1, it is characterised in that described Chinese medicine compound
Preparation includes the composition of following weight portion: Radix Pulsatillae 150-300g, Rhizoma Coptidis 75-125g, Radix Scutellariae 100-200g, Rhizoma Atractylodis 100-
200g, Radix Rhodomyrti 100-200g, Radix Astragali 75-125g, Radix potentillae anserinae 75-125g, Radix seu Caulis Embeliae Parviflorae 75-125g, Herba Erodii 75-125g, dimension are raw
Element E150-300mg, EGF1.5 × 106-2.5×106IU。
A kind of compound Chinese medicinal preparation preventing baby pig diarrhoea the most as claimed in claim 3, it is characterised in that described Chinese medicine compound
Preparation includes the composition of following weight portion: Radix Pulsatillae 200g, Rhizoma Coptidis 100g, Radix Scutellariae 150g, Rhizoma Atractylodis 150g, Radix Rhodomyrti 150g, Huang
Stilbene 100g, Radix potentillae anserinae 100g, Radix seu Caulis Embeliae Parviflorae 100g, Herba Erodii 100g, vitamin E2 00mg, EGF2 × 106IU。
A kind of compound Chinese medicinal preparation preventing and treating baby pig diarrhoea the most as claimed in claim 4, it is characterised in that described Chinese medicine compound
Preparation is powder, capsule, oral liquid, granule or tablet.
6. the preparation method of the compound Chinese medicinal preparation of a preventing and treating baby pig diarrhoea as claimed in claim 5, it is characterised in that institute
State preparation method to specifically comprise the following steps that
1) Radix Pulsatillae, Rhizoma Coptidis, Radix Scutellariae, Rhizoma Atractylodis, Radix Rhodomyrti, the Radix Astragali, Radix potentillae anserinae, Radix seu Caulis Embeliae Parviflorae, Herba Erodii are added 8-15 times amount soak by water
2-3 time, each 1-2 hour, merge decoction liquor, filter, be evaporated to relative density 1.20 ~ 1.28(50 DEG C), be dried to do
Cream；
2) dried cream powder is broken into fine powder, crosses 100 mesh sieves, add vitamin E, EGF and dextrin, mixing, carry out pelletization treatment subsequently
And be dried, obtain compound particles, then in compound particles, add magnesium stearate, it is thus achieved that capsule 's content, by described glue
Capsule content loading capsule housing i.e. obtains capsule.
The preparation method of a kind of compound Chinese medicinal preparation preventing and treating baby pig diarrhoea the most as claimed in claim 6, it is characterised in that step
Rapid 1) in, amount of water is 10 times amount water, and decocting number of times is 3 times, each 1 hour.
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| CN106729629A (en) * | 2017-03-01 | 2017-05-31 | 中悦民安（北京）科技发展有限公司 | A kind of compound Chinese medicinal preparation and preparation method for preventing and treating avian colibacillosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103356833A (en) * | 2013-06-28 | 2013-10-23 | 镇江天和生物技术有限公司 | Compound preparation used for controlling nutritional diarrhea of weaned piglet |
| CN103432267A (en) * | 2013-08-26 | 2013-12-11 | 山东省农业科学院畜牧兽医研究所 | Traditional Chinese medicinal composition for pigs and application of traditional Chinese medicinal composition |
| CN105497878A (en) * | 2015-12-31 | 2016-04-20 | 中悦民安（北京）科技发展有限公司 | Compound preparation for treating animal diarrhea and preparation method of compound preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103356833A (en) * | 2013-06-28 | 2013-10-23 | 镇江天和生物技术有限公司 | Compound preparation used for controlling nutritional diarrhea of weaned piglet |
| CN103432267A (en) * | 2013-08-26 | 2013-12-11 | 山东省农业科学院畜牧兽医研究所 | Traditional Chinese medicinal composition for pigs and application of traditional Chinese medicinal composition |
| CN105497878A (en) * | 2015-12-31 | 2016-04-20 | 中悦民安（北京）科技发展有限公司 | Compound preparation for treating animal diarrhea and preparation method of compound preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106729629A (en) * | 2017-03-01 | 2017-05-31 | 中悦民安（北京）科技发展有限公司 | A kind of compound Chinese medicinal preparation and preparation method for preventing and treating avian colibacillosis |
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