CN104547126A - Traditional Chinese medicine composition for treating bacterial diarrhea of poultry - Google Patents

Traditional Chinese medicine composition for treating bacterial diarrhea of poultry Download PDF

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CN104547126A
CN104547126A CN201510024414.2A CN201510024414A CN104547126A CN 104547126 A CN104547126 A CN 104547126A CN 201510024414 A CN201510024414 A CN 201510024414A CN 104547126 A CN104547126 A CN 104547126A
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chinese medicine
medicine composition
traditional chinese
diarrhea
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张丁华
王艳丰
曹智高
陈海燕
高靖
闫民朝
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HENAN AGRICULTURAL HIGH-TECH PARK CO LTD
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HENAN AGRICULTURAL HIGH-TECH PARK CO LTD
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

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Abstract

The invention discloses a traditional Chinese medicine composition for treating bacterial diarrhea of poultry, and belongs to the technical field of traditional Chinese medicine veterinary medicines. The traditional Chinese medicine composition mainly comprises the following medicine prescriptions in parts by weight: 5-15 parts of sun euphorbia herb, 15-25 parts of parslane herb, 5-15 parts of Japanese hop herb, 15-25 parts of Indian buead, 10-20 parts of pomegranate bark, 10-20 parts of Chinese pulsatilla root, 10-15 parts of coptis chinensis, 10-15 parts of dark plum fruit and 2-8 parts of liquorice root. The traditional Chinese medicine composition disclosed by the invention has the effects of strengthening the intestines and stopping diarrhea, resisting bacteria and diminishing inflammation, repairing intestinal mucosa, protecting barrier functions of the intestinal mucosa and enhancing the disease resistance of the body, and can be used for preventing and treating various syndromes such as bacterial diarrhea and intractable watery diarrhea of the poultry; the traditional Chinese medicine composition is small in toxic or side effects and high in safety, does not have medicine resistance, and is not easy to cause medicine residues; the traditional Chinese medicine composition is reasonable in compatibility, easily-available in raw material and low in production cost, and can be applied to poultry farms for preventing diarrhea; and by virtue of clinical application, the traditional Chinese medicine composition has very good prevention and treatment effects on bacterial diarrhea of the poultry, and ensures that the cure rate can reach 89.57%, and the effective rate can reach 96.90%.

Description

A kind of Chinese medicine composition for the treatment of fowl bacterial diarrhea
Technical field
The invention belongs to Chinese medicine veterinary drug technical field, be specifically related to a kind of Chinese medicine composition for the treatment of fowl bacterial diarrhea.
Background technology
Diarrhoea is the common disease of poultry, causes the more because have of poultry diarrhea, and as stressors, feed factor, environmental factors, epidemic disease factor and inappropriate medication etc., wherein epidemic disease is the main factor causing poultry diarrhea.The pathogen of poultry diarrhea is caused to have antibacterial, virus, fungus and parasite etc., modal is bacterial diarrhea, Main Pathogenic Bacteria has pasteurella multocida, Salmonella, streptococcus, escherichia coli, bacillus perfringens, shigella, riemerella anatipestifer etc., the wherein diarrhoea that causes because of escherichia coli, Salmonella and pasteurellosis bacillus of poultry, because the loss that its M & M is high, cause is large, be three large bacterial diseasees of harm aviculture.Poultry long-term diarrhea can cause gastrointestinal dysfunction, loss of appetite, malnutrition, poor growth, fertility performance to decline, and has a strong impact on the economic benefit of aviculture.
At present, medical treatment is the main method controlling fowl bacterial diarrhea, but due to abuse of antibiotics, causes certain drug resistance to body, carrys out very large problem also to food seat belt simultaneously, constitutes great threat to human health.
Along with China's aviculture is progressively to intensive, scale, industrialization and standardized production future development, the development of fowl medicine turns to low toxicity, noresidue, high potency drugs.Chinese herbal medicine belongs to natural drug, its wide material sources, cheap, and containing a large amount of active skull cap components, as polysaccharide, tannin, alkaloid, glycoside, volatile oil, organic acid, protein, aminoacid and enzyme etc., noresidue, not easily develop immunity to drugs and drug resistance, treating both the principal and secondary aspects of a disease, safety and low toxicity, long-term interpolation can strengthen animal white cytophagy, improve body non-specific immunity, strengthen premunition and anti allergic reaction ability, promoting digestion and invigorating the stomach, expelling intestinal worms and removing food stagnancy, promote growth of animal, improve the advantages such as meat, application herbal control fowl diseases has unique advantage compared with Western medicine.
Summary of the invention
Object of the present invention is intended to provide a kind of Chinese medicine composition for the treatment of fowl bacterial diarrhea.
Based on above object, the present invention takes following technical scheme:
Treat a Chinese medicine composition for fowl bacterial diarrhea, the flavour of a drug primarily of following weight portion form: Herba Euphorbiae Helioscopiae 5 ~ 15 parts, Herba Portulacae 15 ~ 25 parts, Herba humuli scandentis 5 ~ 15 parts, 15 ~ 25 parts, Poria, Pericarpium Granati 10 ~ 20 parts, the Radix Pulsatillae 10 ~ 20 parts, Rhizoma Coptidis 10 ~ 15 parts, Fructus Mume 10 ~ 15 parts, 2 ~ 8 parts, Radix Glycyrrhizae.
Preferably, described Chinese medicine composition also comprises the Radix Sophorae Flavescentis of 5 ~ 15 weight portions.
Preferably, the weight of described Chinese medicine composition consists of: Herba Euphorbiae Helioscopiae 8 ~ 12 parts, Herba Portulacae 17 ~ 22 parts, Herba humuli scandentis 8 ~ 12 parts, 17 ~ 22 parts, Poria, Pericarpium Granati 13 ~ 17 parts, the Radix Pulsatillae 13 ~ 17 parts, Rhizoma Coptidis 10 ~ 13 parts, Fructus Mume 10 ~ 13 parts, 4 ~ 6 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 8 ~ 12 parts.
Preferably, the weight of described Chinese medicine composition consists of: Herba Euphorbiae Helioscopiae 10 parts, Herba Portulacae 20 parts, Herba humuli scandentis 10 parts, 20 parts, Poria, Pericarpium Granati 15 parts, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 12 parts, Fructus Mume 12 parts, 5 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 10 parts.
For convenience of using, by following method, Chinese medicine composition of the present invention is made ultrafine powder: each flavour of a drug are after remove impurity, washing, drying, by each single medicinal material in order one by one at crusher for crushing to 60 order, then mix homogeneously makes common flour, finally putting into super micron mill is again crushed to 400 orders, detect qualified after, sealed packaging preserve.Superfine communication technique is utilized to carry out breaking cellular wall processing to Chinese medicine, the effective ingredient in medical material can be enable fully to discharge, surface area increases, and effective ingredient increases at gastrointestinal dissolubility, the features such as drug dose is few, convenient drug administration, instant effect, short treating period, cost are low.
Chinese veterinarian is dialectical thinks that poultry bacterial diarrhoea belongs to pestilence category more, and belong to affection due to external wind and heat, form damp invasion of lower energizer between accumulation of heat intestinal, accumulation of heat is burnt in upper, middle and lower three, causes excessive heat in SAN JIAO, consume body fluid.Control heat-clearing and toxic substances removing, dampness-eliminating and dysentery-stopping, clearing away heat and promoting production of body fluid to be main.In Chinese medicine composition of the present invention, Herba Euphorbiae Helioscopiae cold nature, bitter in the mouth, inducing diuresis to remove edema, expectorant, parasite killing, heat-clearing and toxic substances removing, breath with cough for edematous asthma, phlegm retention, the disease such as malaria, bacillary dysentery; Herba Portulacae is cold in nature, sweet in the mouth is sour, heat-clearing and toxic substances removing, cooling blood for hemostasis, for diseases such as pyretic toxicity dysentery, pyretic stranguria, urine retention, dysentery, toxic-heat and blood stasis; Herba humuli scandentis is sweet, bitter, cold, and heat clearing away, diuresis, the silt that disappears, removing toxic substances, for diseases such as dysuria, malaria, diarrhoea, dysentery; Poria invigorating the heart and spleen, eliminating dampness and diuresis, for stagnation of dampness due to deficiency of the spleen and all diseases of retention of water-damp in the body; Pericarpium Granati astringing intestine to stop diarrhea, hemostasis, anthelmintic, for diseases such as chronic diarrhea chronic dysentery, abdominal pain due to worm stagnation; Radix Pulsatillae heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, have inhibitory action to dysentery bacterium, escherichia coli, avian pasteurella multocida; Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication, be broad spectrum antibiotic, have stronger inhibitory action to Salmonella Pullorm, escherichia coli, Bacillus typhi, pasteurella multocida etc.; Fructus Mume convergence is promoted the production of body fluid, relieving colic caused by ascaris anthelmintic, for chronic malaria, and chronic diarrhea, the diseases such as dysentery; Radix Glycyrrhizae is used for weakness of the spleen and stomach, and diarrhoea stomachache waits disease, has antiinflammatory, antiviral, protecting liver and detoxication and strengthens the effects such as immunologic function, also can play the effect of coordinating the actions of various ingredients in a prescription; Radix Sophorae Flavescentis heat clearing and damp drying, wind dispelling insecticide.
In top, Herba Euphorbiae Helioscopiae, Herba Portulacae are monarch drug, play an important role to Prevention and Curation bacillary dysentery, also have better therapeutic effect to the diarrhoea that bacillus phasiani septicus causes; Herba humuli scandentis, Pericarpium Granati, the Radix Pulsatillae are ministerial drug, strengthen the therapeutical effect of Herba Euphorbiae Helioscopiae, Herba Portulacae; Rhizoma Coptidis, Poria, Fructus Mume, Radix Sophorae Flavescentis are adjuvant drug, help out to the treatment of Herba Euphorbiae Helioscopiae, Herba Portulacae; Radix Glycyrrhizae for making medicine, the effect of coordinating the actions of various ingredients in a prescription.
Beneficial effect of the present invention: the effect that the present invention has intestine-stabling and anti-diarrheal, repairs intestinal mucosa, protects function of intestinal mucosa barrier in patient and enhancing body resistance against diseases, can cure poultry bacterial diarrhoea, all diseases of intractable watery diarrhea; Toxic and side effects is little, drug safety is high, not easily in sick fowl body accumulation toxin, have no drug resistance; Compatibility is reasonable, and raw material is easy to get, and production cost is low, can do prophylactic agent for poultry-farm; Have good prevention effect by clinical practice to poultry bacterial diarrhoea, cure rate can up to 89.57%, and effective percentage up to 96.90%, also can have obvious effect to promoting the laying rate of poultry more.
Usage 1: Chinese medicine composition of the present invention is pulverized for end (400 order), mixed feeding: add 5 ~ 10g, 2 times/d in every kilogram of feed, be used in conjunction 5 ~ 7 days, or according to sick fowl diseases shape and medication effect determination drug treatment; Mixed drink: after soaking 30min in the ratio of Chinese medicine composition and boiling water 1:4, get the ratio of supernatant in 1:300, be blended in 1/3 water of whole day amount of drinking water to concentrate and drink, medicinal residues admix feedstuff mixed feeding by 0.5% again, be used in conjunction 5 ~ 7 days, or according to sick fowl diseases shape and medication effect determination drug treatment.Prophylactic reduces by half.
Usage 2: quantitatively take Chinese medicine composition of the present invention, adds the soak by water 2h of 10 times of volumes, after filtration, adds 8 times of volume soak by water 2h in medicinal residues again, merges 2 filtrates, uses Rotary Evaporators to become to be equivalent to medicinal liquid concentrating under reduced pressure containing crude drug amount 1.0gmL -1, adjust pH to 7.2 ~ 7.4.Autoclaving, 4 DEG C save backup.Gavage by every poultry 1 ~ 3mL, every day 1 ~ 2 time, be used in conjunction 5 ~ 7 days.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described.
embodiment 1
Treat a Chinese medicine composition for fowl bacterial diarrhea, be made up of the flavour of a drug of following weight portion: Herba Euphorbiae Helioscopiae 10 parts, Herba Portulacae 20 parts, Herba humuli scandentis 10 parts, 20 parts, Poria, Pericarpium Granati 15 parts, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 12 parts, Fructus Mume 12 parts, 5 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 10 parts.
embodiment 2
Treat a Chinese medicine composition for fowl bacterial diarrhea, be made up of the flavour of a drug of following weight portion: Herba Euphorbiae Helioscopiae 8 parts, Herba Portulacae 22 parts, Herba humuli scandentis 12 parts, 17 parts, Poria, Pericarpium Granati 13 parts, the Radix Pulsatillae 17 parts, Rhizoma Coptidis 13 parts, Fructus Mume 10 parts, 6 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 12 parts.
embodiment 3
Treat a Chinese medicine composition for fowl bacterial diarrhea, be made up of the flavour of a drug of following weight portion: Herba Euphorbiae Helioscopiae 12 parts, Herba Portulacae 17 parts, Herba humuli scandentis 8 parts, 22 parts, Poria, Pericarpium Granati 17 parts, the Radix Pulsatillae 13 parts, Rhizoma Coptidis 10 parts, Fructus Mume 13 parts, 4 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 9 parts.
embodiment 4
Treat a Chinese medicine composition for fowl bacterial diarrhea, be made up of the flavour of a drug of following weight portion: Herba Euphorbiae Helioscopiae 5 parts, Herba Portulacae 25 parts, Herba humuli scandentis 15 parts, 15 parts, Poria, Pericarpium Granati 10 parts, the Radix Pulsatillae 10 parts, Rhizoma Coptidis 15 parts, Fructus Mume 15 parts, 4 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 15 parts.
embodiment 5
Treat a Chinese medicine composition for fowl bacterial diarrhea, be made up of the flavour of a drug of following weight portion: Herba Euphorbiae Helioscopiae 15 parts, Herba Portulacae 15 parts, Herba humuli scandentis 5 parts, 25 parts, Poria, Pericarpium Granati 20 parts, the Radix Pulsatillae 20 parts, Rhizoma Coptidis 11 parts, Fructus Mume 11 parts, 2 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 5 parts.
embodiment 6
Treat a Chinese medicine composition for fowl bacterial diarrhea, be made up of the flavour of a drug of following weight portion: Herba Euphorbiae Helioscopiae 11 parts, Herba Portulacae 21 parts, Herba humuli scandentis 9 parts, 19 parts, Poria, Pericarpium Granati 17 parts, the Radix Pulsatillae 13 parts, Rhizoma Coptidis 13 parts, Fructus Mume 10 parts, 8 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 8 parts.
embodiment 7
Treat a Chinese medicine composition for fowl bacterial diarrhea, be made up of the flavour of a drug of following weight portion: Herba Euphorbiae Helioscopiae 11 parts, Herba Portulacae 21 parts, Herba humuli scandentis 9 parts, 19 parts, Poria, Pericarpium Granati 17 parts, the Radix Pulsatillae 13 parts, Rhizoma Coptidis 13 parts, Fructus Mume 10 parts, 8 parts, Radix Glycyrrhizae.
embodiment 8
Treat a Chinese medicine composition for fowl bacterial diarrhea, be made up of the flavour of a drug of following weight portion: Herba Euphorbiae Helioscopiae 14 parts, Herba Portulacae 24 parts, Herba humuli scandentis 7 parts, 21 parts, Poria, Pericarpium Granati 16 parts, the Radix Pulsatillae 19 parts, Rhizoma Coptidis 13 parts, Fructus Mume 12 parts, 3 parts, Radix Glycyrrhizae.
effect experimental 1
(1) experimental program: in certain plant, to stop using other drug to there is the chicken of bacterial diarrhea, the Chinese medicine composition of Example 1, pulverize as end, cross 400 mesh sieves, in every kilogram of feed, add the dispensing of 5 ~ 10g spice, continuous use 4 ~ 10 days, improve feeding and management condition, and in drinking-water, add 3% ~ 5% glucose, 0.1% electrolysis multidimensional, to strengthen disease fowl resistivity.Treatments period observes disease fowl state, Estimating curative effect.
(2) Outcome measure:
Cure: tested chicken medication, after 3 days, recovers dysregulated appetite and the mental status.Cut open inspection and there is no obvious Alimentary tract disease person for curing.
Effective: tested chicken medication is after 5 days, and the mental status and appetite take a turn for the better, and feces has obvious transformation, for effective.
Take a turn for the better: tested chicken medication is after 8 days, and the mental status and appetite are slightly poor, and feces slightly changes, and be effective at test end of term generation died.
Invalid: continuous use 10 days, symptom does not have clear improvement, and even increases the weight of or dead, cut open inspection have obvious Alimentary tract disease feature for invalid.
(3) experimental result: apply Chinese medicine composition of the present invention to there being 806 of obvious symptom of diarrhea sick chickens and treat.Therapeutic effect statistical result is in table 1.
As shown in Table 1, utilize the Bacterial diarrhea of traditional Chinese medicine composition for treating chicken of the present invention, cure rate 89.57%, effective percentage reaches 96.90%, evident in efficacy.
effect experimental 2:
On May 12nd, 2013, the 190 age in days laying hen 5000 that Fengqiu County, Henan Province Lee raises, there is suddenly diarrhoea in about 30% laying hen, disease sees that disease chicken spirit is depressed, and feather is fluffy and disorderly, and feed intake declines or gives up absolutely, drinking-water increases, and cockscomb reduces, pale, and abdominal part is sagging, recurrent diarrhea, ash discharge white or soil sample feces, perianal, hypogastric feather faecal contamination, laying rate declines, some limpings, most chicken performance progressive emaciation, exhaustion.Cut open inspection liver enlargement, hyperemia, the necrosis region that heart and liver surface have foxtail millet grain size canescence quantity not etc.Pericarditis, pericardial effusion.Follicle distortion, degeneration, variable color.Kidney has swelling in various degree.Cut open inspection, laboratory diagnosis through clinical diagnosis, pathology, be diagnosed as the diarrhoea that S. pullonum causes.
Get disease chicken 400 at random, be divided into 2 groups, often organize 200, one group is traditional Chinese medicine composition for treating group of the present invention, and another group is antibiotic therapy group, treats under identical feeding and management condition.
Therapeutic Method: the Chinese medicine composition of Example 1, pulverizes as end, crosses 400 mesh sieves, adds the administration of 10g mixed feeding in every kilogram of feed.Isolate the sick chicken of especially severe, not material feeding, treat according to usage 2, often only sick chicken fills with 2mL, 2 times/d.Experimental period is 7 days, observes chicken group every day period and to suffer from diarrhoea situation, the course of disease, case fatality rate, cure rate etc.
Antibiotic therapy group amikacin sulfate solubility, adopt the mode of mixed drink administration, dosage is illustratively determined, and experimental period is 7 days, observes chicken group every day period and to suffer from diarrhoea situation, the course of disease, case fatality rate, cure rate etc., in table 2.
As shown in Table 2, the Chinese medicine composition group of embodiment 1 to laying hen bacterial diarrhea therapeutic effect significantly better than antibiotic group.
Two groups of laying hens of curing carry out conventional feeding and management respectively, with 10 days for period, observe Egg Production of Laying Hens situation, and statistical average is laid eggs number, in table 3.
As shown in Table 3, the laying hen after healing, Chinese medicine composition group laying rate is higher than antibiotic group 8 percentage points.
effect experimental 3:
Broiler breeding family, Zhongmou County, Henan Province, 35 Day-old Broiler Chickens 4200, disease is seen chicken group spirit and is searched for food normal, and the chicken group uniformity is poor, and part feather is inverse vertical, and mortality rate about 1%, dying of illness, chicken figure is better, head is large.Face upward time dead dead, stretch after two lower limbs or a lower limb towards last lower limb backwards, loose and watery stool, inside has and does not digest feedstuff, occasionally draws water phenomenon.Cut open inspection duodenum and small intestinal leading portion intestinal wall thickening, inside have the intestinal mucosa and indigested feedstuff that come off, some intestinal mucosa have the petechia of needle point size.Liver surface has the ecchymosis of alluvial, and spleen is pale, is full of feedstuff in crop, and be full of yellow green content in muscular stomach, cecal tonsil is hemorrhage, and tentative diagnosis is broiler intestinal poison syndrome.
Therapeutic Method: the Chinese medicine composition of Example 2 is pulverized as end, cross 400 mesh sieves, mixed drink: after soaking 30min in the ratio of Chinese medicine composition and water 1:4, get the ratio of supernatant in 1:300, be blended in 1/3 water of whole day amount of drinking water to concentrate and drink, medicinal residues admix feedstuff mixed feeding by 0.5% again, are used in conjunction 7 days.
Medication is after 3 days, and chicken group feces recovers normal gradually, draws water phenomenon to disappear, and inverse vertical person is rare for feather, and when rear tracking return visit is delivered for sale, chicken body weight reaches standard body weight.
effect experimental 4:
On May 20th, 2012, Kaifeng County, Henan Province laying ducks plant, 12000 37 age in days duck morbidities of raising, disease sees diarrhoea, draws yellow green loose stool, and perianal feather is polluted by loose stool.With heating, subtract food, foot soft, turn-take, the symptom such as opisthotonus, the sick duck death of part, falls ill 15 days, used the treatments such as LIJUNJING, bacitracin zinc, chlortetracycline, florfenicol between period of disease, all without positive effect.Cut open inspection to die of illness duck 10, major lesions is heart, liver, balloon surface have yellow-white fibrin deposition.Spleen enlargement, has the downright bad point of canescence.Intestinal wall is congested, is full of the frothy liquid of yellow green band in intestinal tube.Tentative diagnosis is infectious serositis in duck.
Therapeutic Method: the Chinese medicine composition of Example 3 is pulverized as end, crosses 400 mesh sieves, adds the dispensing of 10g spice in every kilogram of feed.Isolate the sick duck of especially severe, not material feeding, treat according to usage 2, often only sick chicken fills with 2mL, 2 times/day.After 5 days, the sick duck of 91% is cured, and the continuation medication do not recovered completely is after 5 days, and whole duck group recovers normal substantially.Eliminate the sick duck that part is seriously ill, therapeutic effect is bad.
effect experimental 5:
On July 19th, 2014, Weizhi County, Henan Province raiser buys 4500 817 broiler from Xinxiang, and 4 ages in days start morbidity, and disease sees that disease chicken spirit is depressed, loss of appetite, and feather is fluffy and disorderly, arranges white watery stool.Sickness rate 13.7%, mortality rate 5.9%.Cut open the visible liver surface of inspection and have the downright bad point of the large canescence of needle point, heart hat fat is hemorrhage, spleen renomegaly.Pullorum Disease and shigellosis mixed infection is diagnosed as through clinical diagnosis and laboratory diagnosis.
Therapeutic Method: the Chinese medicine composition of Example 4 is pulverized as end, crosses 400 mesh sieves, after soaking 30min in the ratio of Chinese medicine composition and boiling water 1:4, get the ratio of supernatant in 1:300, be blended in 1/3 water of whole day amount of drinking water to concentrate and drink, medicinal residues admix feedstuff mixed feeding by 0.5% again, are used in conjunction 5 days.After result Chinese medicine composition medication of the present invention, the 2nd day feces starts to improve, and within the 5th day, cures, cure rate 90.1%.

Claims (4)

1. treat a Chinese medicine composition for fowl bacterial diarrhea, the flavour of a drug primarily of following weight portion form: Herba Euphorbiae Helioscopiae 5 ~ 15 parts, Herba Portulacae 15 ~ 25 parts, Herba humuli scandentis 5 ~ 15 parts, 15 ~ 25 parts, Poria, Pericarpium Granati 10 ~ 20 parts, the Radix Pulsatillae 10 ~ 20 parts, Rhizoma Coptidis 10 ~ 15 parts, Fructus Mume 10 ~ 15 parts, 2 ~ 8 parts, Radix Glycyrrhizae.
2. the Chinese medicine composition for the treatment of fowl bacterial diarrhea according to claim 1, it is characterized in that, described Chinese medicine composition also comprises the Radix Sophorae Flavescentis of 5 ~ 15 weight portions.
3. the Chinese medicine composition for the treatment of fowl bacterial diarrhea according to claim 2, it is characterized in that, the weight of described Chinese medicine composition consists of: Herba Euphorbiae Helioscopiae 8 ~ 12 parts, Herba Portulacae 17 ~ 22 parts, Herba humuli scandentis 8 ~ 12 parts, 17 ~ 22 parts, Poria, Pericarpium Granati 13 ~ 17 parts, the Radix Pulsatillae 13 ~ 17 parts, Rhizoma Coptidis 10 ~ 13 parts, Fructus Mume 10 ~ 13 parts, 4 ~ 6 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 8 ~ 12 parts.
4. the Chinese medicine composition for the treatment of fowl bacterial diarrhea according to claim 3, it is characterized in that, the weight of described Chinese medicine composition consists of: Herba Euphorbiae Helioscopiae 10 parts, Herba Portulacae 20 parts, Herba humuli scandentis 10 parts, 20 parts, Poria, Pericarpium Granati 15 parts, the Radix Pulsatillae 15 parts, Rhizoma Coptidis 12 parts, Fructus Mume 12 parts, 5 parts, Radix Glycyrrhizae, Radix Sophorae Flavescentis 10 parts.
CN201510024414.2A 2014-11-28 2015-01-19 Traditional Chinese medicine composition for treating bacterial diarrhea of poultry Pending CN104547126A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107496532A (en) * 2017-09-14 2017-12-22 台江县金利禽业有限责任公司 A kind of Chinese medicine composition for treating chicken dysentery and preparation method thereof
CN109745418A (en) * 2019-03-04 2019-05-14 黑龙江省野生动物研究所 A kind of Chinese herbal feed additive preventing and treating livestock and poultry diarrhea
CN114949064A (en) * 2020-12-16 2022-08-30 河南牧业经济学院 Preparation method of traditional Chinese medicine microecological preparation for treating enteritis and diarrhea of laying hens
CN114949064B (en) * 2020-12-16 2023-04-28 河南牧业经济学院 Preparation method of traditional Chinese medicine microecological preparation for treating enteritis and diarrhea of laying hens
CN113209184A (en) * 2021-05-31 2021-08-06 郑州金企源生物科技有限公司 Veterinary traditional Chinese medicine crude extract particle

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