CN106511635A - Medicinal composition for improving immunity of poultry - Google Patents
Medicinal composition for improving immunity of poultry Download PDFInfo
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- CN106511635A CN106511635A CN201611021765.9A CN201611021765A CN106511635A CN 106511635 A CN106511635 A CN 106511635A CN 201611021765 A CN201611021765 A CN 201611021765A CN 106511635 A CN106511635 A CN 106511635A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
- A61K36/855—Clerodendrum, e.g. glorybower
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
Abstract
The invention provides a medicinal composition for improving the immunity of poultry. The medicinal composition comprises, by weight, 10-30 parts of isatis root, 15-45 parts of Folium Isatidis, 6-18 parts of glutinous rehmannia, 6-18 parts of radix paeoniae rubra, 6-18 parts of Ligustri Lucidi Fructus, 6-18 parts of epimeddium and 6-18 parts of licorice root. The medicinal composition has the advantages of effective improvement of the immunity of the poultry, no medicine residual, no medicine resistance, and no influences on normal growth of the poultry.
Description
Technical field
The present invention relates to a kind of Chinese veterinary medicinal composition, and in particular to a kind of pharmaceutical composition of raising immunity of poultry.
Background technology
With the continuous development and the intensification of intensive degree of livestock and poultry breeding industry, the growing environment of livestock and poultry is constantly changed
Kind, production performance is farthest played, meanwhile, activity is restricted, and adds high-caliber production performance, livestock and poultry itself
Regulative mechanism is relatively low, and resistance is poor, the such as Changes in weather of the several factors in feeding and management, cut off the water and electricity supply, change keeper,
Vaccine immunity etc. is all likely to become the inducement of its morbidity.
At this stage, traditional cultivation idea has not existed, and culturist generally adheres to " putting prevention first, anti-overweighting is controlled "
Policy, for the prevention and control of disease, people rely primarily on the immunity inoculation of vaccine, and vaccine immunity is decision livestock and poultry cultivation success or failure
Key point.But in recent years, with the development of aquaculture, inhibitive ability of immunity disease incidence increases year by year, when livestock and poultry infect
During these diseases, fowl poultry immune systemic-function is damaged, and antigen responsibility is declined, and affects the vaccine immunity effect of other diseases
Really, cause immuning failure.
With its aboundresources, effect is extensive for Chinese herbal medicine, enjoys favor the advantages of will not produce drug resistance, is carried using Chinese herbal medicine
The immunity of high poultry, replaces the medicines such as antibiotic, vaccine, it is to avoid the drawback such as medicament residue and antibiotics resistance becomes research
Popular direction.
The content of the invention
It is an object of the invention to provide one kind effectively improves immunity of poultry, drug residue free, has no drug resistance and do not affect
The pharmaceutical composition of chicken growth.
The present invention is adopted the following technical scheme that：
A kind of pharmaceutical composition for improving immunity of poultry, which includes the component of following weight portion：10 ~ 30 parts of Radix Isatidis, smalt
6 ~ 18 parts of 15 ~ 45 parts of leaf, 6 ~ 18 parts of glutinous rehmannia, 6 ~ 18 parts of the radix paeoniae rubrathe, 6 ~ 18 parts of the fruit of glossy privet, 6 ~ 18 parts of barrenwort and Radix Glycyrrhizae.
Further, which includes the component of following weight portion：15 ~ 25 parts of Radix Isatidis, 20 ~ 35 parts of folium isatidis, glutinous rehmannia 10 ~ 14
10 ~ 14 parts of part, 10 ~ 14 parts of the radix paeoniae rubrathe, 10 ~ 14 parts of the fruit of glossy privet, 10 ~ 14 parts of barrenwort and Radix Glycyrrhizae.
Further, which includes the component of following weight portion：20 parts of Radix Isatidis, 30 parts of folium isatidis, 12 parts of glutinous rehmannia, the radix paeoniae rubrathe 12
12 parts of part, 12 parts of the fruit of glossy privet, 12 parts of barrenwort and Radix Glycyrrhizae.
Radix Isatidis：Chinese medicine name.Hardship, trembles with fear.With clearing heat and detoxicating, the effect of cool blood profit pharynx.It is usually used in poison during warm epidemic disease, heating pharynx
Bitterly, febrile virulent maculae, mumps, scarlet fever, major part pestilence, erysipelas, carbuncle swells.
Folium isatidis：Chinese medicine name.Cure mainly：Heat toxin sends out the diseases such as spot, erysipelas, abscess of throat, aphthae, sore and toxic.In recent years
Carry out this medicine clinically extensively to apply, in addition to it can use and control above-mentioned all diseases, can be used for the strongly fragrant lung of phlegm heat, cough up phlegm yellow thick again.
Glutinous rehmannia：Clearing heat and promoting fluid, cool blood, hemostasis.For consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, spot dermexanthesis are spitted blood, bleeding from five sense organs or subcutaneous tissue, throat
Swell and ache.
The radix paeoniae rubrathe：For the ranunculaceae plant radix paeoniae rubrathe or the dry root of the river radix paeoniae rubrathe.Bitter, cold nature.There are clearing heat and cooling blood, promoting blood circulation
Effect.
The fruit of glossy privet：Kidney tonifying enriching yin simply, the Chinese medicine for nourishing the liver to improve visual acuity, can control kidney deficiency and liver, dizzy syrigmus, graying of hair and
The illnesss such as two blurred visions paste.Sweet, bitter, cold.Tonify the liver and kidney, improving eyesight, clearind deficient heat.
Barrenwort：Pain in low back and legs is cured mainly, numb limb, hemiplegia, neurasthenia are forgetful, tinnitus, it is dizzy to wait disease.
Radix Glycyrrhizae：Gas is micro-, and taste is sweet and special.Indication is clearing heat and detoxicating, expelling phlegm and arresting coughing, gastral cavity abdomen etc..
Preparation method is：Take the backflow of above-mentioned medicinal material to decoct 3 times, i.e., plus 5 ~ 10 times of amount water refluxing extractions 3 times, 1 hour every time,
It is evaporated to suitable density 1.05 ~ 1.25.
As the preferred of preparation method：Taking above-mentioned medicinal material adds 8 times of amount decoctings to boil 3 times, 1 hour every time, is evaporated to phase
When density 1.15.
Usage and consumption are：100kg is watered per 100g concentrates, with the deal of every 5 ~ 10ml of chicken, in adding water fountain,
Once a day, for chicken free water, after adding the water of medicine to drink, drink for chicken to running water.Can Long-Time Service.
Above-mentioned concentrate can be obtained formulation：Pre-mixing agent, pulvis, powder, tablet, granule, oral liquid or parenteral solution.This
When the pharmaceutical composition of invention is used as pulvis, can be Jing after the impurity that screening is removed in raw material, drying and crushing crosses 80 mesh sieves,
Prepared pulvis, as chicken feed addictive, is added in feed by 1wt%.
The beneficial effects of the present invention is：The present invention follows drug matching principle, strengthening vital QI to eliminate pathogenic factors, clearing heat and detoxicating, can strengthen
Poultry physique, improve immunity of organisms, strengthen resistivity of the poultry to common diseases such as influenza, enteritis, gastritis, antibiotic-free and
Chemicals residue, reduces antibiotic residue in animality product.The present invention Chinese medicine composition can Long-Time Service, do not produce anti-
The property of medicine, does not affect the normal growth of chicken to develop in use.
Specific embodiment
With reference to embodiment, the present invention is described in detail.The scope of the present invention is not limited to embodiment, this area
Technical staff makes any change in the range of claim is limited and falls within the scope of protection of the invention.
Embodiment 1
A kind of pharmaceutical composition for improving immunity of poultry, which includes the component of following weight portion：10 parts of Radix Isatidis, folium isatidis 15
6 parts of part, 6 parts of glutinous rehmannia, 6 parts of the radix paeoniae rubrathe, 6 parts of the fruit of glossy privet, 6 parts of barrenwort and Radix Glycyrrhizae.Plus 5 times take the backflow of above-mentioned medicinal material and decoct 3 times, i.e.,
Amount water refluxing extraction 3 times, 1 hour every time, is evaporated to suitable density 1.05.100kg is watered per 100g concentrates, with per only
The deal of chicken 5ml, in adding water fountain, once a day, for chicken free water, after adding the water of medicine to drink, supplies to running water
Chicken is drunk.
Embodiment 2
A kind of pharmaceutical composition for improving immunity of poultry, which includes the component of following weight portion：30 parts of Radix Isatidis, folium isatidis 45
18 parts of part, 8 parts of glutinous rehmannia, 18 parts of the radix paeoniae rubrathe, 18 parts of the fruit of glossy privet, 18 parts of barrenwort and Radix Glycyrrhizae.Above-mentioned medicinal material backflow decoction 3 times is taken, i.e.,
Plus 10 times of amount water refluxing extractions 3 times, 1 hour every time, it is evaporated to suitable density 1.25.100kg is watered per 100g concentrates,
With the deal of every chicken 10ml, in adding water fountain, once a day, for chicken free water, after adding the water of medicine to drink, to certainly
Water is drunk for chicken.
Embodiment 3
Which includes the component of following weight portion：25 parts of Radix Isatidis, 20 parts of folium isatidis, 10 parts of glutinous rehmannia, 10 parts of the radix paeoniae rubrathe, the fruit of glossy privet 14
10 parts of part, 14 parts of barrenwort and Radix Glycyrrhizae.Plus 8 times of amount water refluxing extractions 3 times take the backflow of above-mentioned medicinal material and decoct 3 times, i.e., 1 is little every time
When, it is evaporated to suitable density 1.15.100kg is watered per 100g concentrates, with the deal of every chicken 8ml, water fountain is added
In, once a day, for chicken free water, after adding the water of medicine to drink, drink for chicken to running water.
Embodiment 4
Including the component of following weight portion：20 parts of Radix Isatidis, 30 parts of folium isatidis, 12 parts of radix rehmanniae recen, 12 parts of the radix paeoniae rubrathe, the fruit of glossy privet 12
12 parts of part, 12 parts of barrenwort and Radix Glycyrrhizae.Plus 8 times of amount water refluxing extractions 3 times take the backflow of above-mentioned medicinal material and decoct 3 times, i.e., 1 is little every time
When, it is evaporated to suitable density 1.15.100kg is watered per 100g concentrates, with the deal of every chicken 8ml, water fountain is added
In, once a day, for chicken free water, after adding the water of medicine to drink, drink for chicken to running water.
Comparative example
Component proportion is as shown in table 1.Method of preparation and use is：Material of getting it filled adds 8 times of amount water backflows to decoct 3 times, and 1.5 is little every time
When, it is evaporated to suitable density 1.15.100kg is watered per 100g concentrates, with the deal of every chicken 8ml, water fountain is added
In, once a day, for chicken free water, after adding the water of medicine to drink, drink for chicken to running water.
The component formula of 1 comparative example 1 ~ 14 of table（Weight portion）.
Effect example
Feed the common chicken feed of same formula before experiment with age in days chicken group daily, experiment starts for chicken to be randomly divided into control group and 11
Individual experimental group.11 experimental groups use the pharmaceutical composition concentrate of embodiment 1 ~ 4 and comparative example 1 ~ 7 respectively.Using method
For：Cut off the water supply before drinking water administration 3 hours.With the deal of every 5 ~ 10ml of chicken, in adding water fountain, once a day, freely drink for chicken
Water, after adding the water of medicine to drink, drinks for chicken to running water, and control group only supplies running water.
Lymphocyte transformation rate is an important indicator for evaluating Immune Function, and the antibody after vaccine immunity
Level then reflects the humoral immunity ability of matrix, so determining the lymphocyte transformation rate of chicken after herbal medicine in use, selects
Antibody IgY against chicken Newcastle Disease is detected as the index of reflection humoral immunity of organism, the Escherichia coli in chicken group's excrement is acquired
Count, above-mentioned each index is used to verify impact of each herbal composite to body's immunity.
The 10th day and the 20th day each group chicken lymphocyte transformation rate are detected, it is big in antibody IgY against chicken Newcastle Disease level and chicken manure
Enterobacteria quantity（cfu/g）, as a result as shown in table 2.
2 herbal composite of table is to chicken lymphocyte transformation rate, newcastle epidemic disease antibody level, Escherichia coli quantity and body
The impact of weight.
As shown in Table 2, after the Chinese medicine composition of Application Example 1 ~ 4,1 ~ 4 group of lymphocyte than control group of embodiment turns
Rate significantly increases, and can significantly improve the cellular immune function of body.1 ~ 7 group of comparative example is suitable with control group, and difference is not obvious.
In terms of the qualification rate of newcastle epidemic disease antibody, 1 ~ 4 group of embodiment is compared with 1 ~ 7 group of improve of control group and comparative example nearly 25%.The group of the present invention
Compound also has prominent effect in terms of Escherichia coli are suppressed, and when the 20th day, the coliform count that 4 groups of embodiment is only tested
Front 1/7th, and the Flora dynamics of 1 ~ 7 group of comparative example and control group are little.The pharmaceutical composition of the present invention is for chicken
Growing inhibitory action of do not play, also 7% being improve compared with control group, 1 ~ 7 group of comparative example has shadow to growing for chicken
Ring, it is low compared with rate of body weight gain for control group.
In sum, the compatibility of medicine of the present invention has synergistic function, can be with using the composition of the present invention
Improve the resistance against diseases of poultry.And lack any medicinal material simply, its effect for the immunity of poultry is improved is all undesirable,
The normal development of poultry is especially also affected, is lost more than gain.
The present invention is described in detail according to the above embodiments.It should be noted that, the embodiment of the above is only for act
Example explanation invention.On the premise of without departing from spirit and substance of the present invention, those skilled in the art can be designed that this
Various alternatives and improvement project of invention, which all should be understood to be within protection scope of the present invention.
Claims (3)
1. it is a kind of improve immunity of poultry pharmaceutical composition, it is characterised in which includes the component of following weight portion：Radix Isatidis
10 ~ 30 parts, 15 ~ 45 parts of folium isatidis, 6 ~ 18 parts of glutinous rehmannia, 6 ~ 18 parts of the radix paeoniae rubrathe, 6 ~ 18 parts of the fruit of glossy privet, 6 ~ 18 parts of barrenwort and Radix Glycyrrhizae 6 ~
18 parts.
2. it is according to claim 1 it is a kind of improve immunity of poultry pharmaceutical composition, it is characterised in which includes as follows
The component of weight portion：15 ~ 25 parts of Radix Isatidis, 20 ~ 35 parts of folium isatidis, 10 ~ 14 parts of glutinous rehmannia, 10 ~ 14 parts of the radix paeoniae rubrathe, the fruit of glossy privet 10 ~ 14
10 ~ 14 parts of part, 10 ~ 14 parts of barrenwort and Radix Glycyrrhizae.
3. it is according to claim 2 it is a kind of improve immunity of poultry pharmaceutical composition, it is characterised in which includes as follows
The component of weight portion：20 parts of Radix Isatidis, 30 parts of folium isatidis, 12 parts of glutinous rehmannia, 12 parts of the radix paeoniae rubrathe, 12 parts of the fruit of glossy privet, 12 parts of barrenwort and
12 parts of Radix Glycyrrhizae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611021765.9A CN106511635A (en) | 2016-11-21 | 2016-11-21 | Medicinal composition for improving immunity of poultry |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611021765.9A CN106511635A (en) | 2016-11-21 | 2016-11-21 | Medicinal composition for improving immunity of poultry |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106511635A true CN106511635A (en) | 2017-03-22 |
Family
ID=58353026
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611021765.9A Pending CN106511635A (en) | 2016-11-21 | 2016-11-21 | Medicinal composition for improving immunity of poultry |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543589A (en) * | 2008-03-26 | 2009-09-30 | 北京大北农动物保健科技有限责任公司 | Compound pharmaceutical composition for curing virus diseases of animals and preparation method thereof |
-
2016
- 2016-11-21 CN CN201611021765.9A patent/CN106511635A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543589A (en) * | 2008-03-26 | 2009-09-30 | 北京大北农动物保健科技有限责任公司 | Compound pharmaceutical composition for curing virus diseases of animals and preparation method thereof |
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Application publication date: 20170322 |