CN103463469B - Prawn Taura syndrome virus disease treatment drug composition and preparation method thereof - Google Patents
Prawn Taura syndrome virus disease treatment drug composition and preparation method thereof Download PDFInfo
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- CN103463469B CN103463469B CN201310342767.8A CN201310342767A CN103463469B CN 103463469 B CN103463469 B CN 103463469B CN 201310342767 A CN201310342767 A CN 201310342767A CN 103463469 B CN103463469 B CN 103463469B
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Abstract
The present invention discloses a prawn Taura syndrome virus disease prevention and treatment drug composition, which is prepared from the following raw materials, by weight: 30-40 parts of dan-shen root, 15-30 parts of radix rehmanniae, 20-35 parts of radix astragali, 20-30 parts of indigowoad leaf, 15-30 parts of cortex moutan, 20-35 parts of hirsute bugleweed herb, 25-35 parts of reed rhizome, and 10-20 parts of weeping forsythia fruit. The invention further discloses a preparation method for the drug composition. The drug composition has the following characteristics that: the formula design is rational, the drugs in the composition are low toxicity traditional Chinese medicines, the composition contains the antibacterial and bacterial inhibition traditional Chinese medicine, and the prawn Taura syndrome virus disease is effectively prevented and treated with the composition. In addition, the preparation method is simple and easy to perform, feeding is convenient, and the method is suitable for mass production.
Description
Technical field
The present invention relates to treat the field of Chinese medicines of shrimps disease, and in particular to one kind treats prawn taura syndrome virosiss
Pharmaceutical composition and preparation method thereof.
Background technology
Prawn taura syndrome virosiss symptom is as follows：Sick shrimp does not eat food or eats food on a small quantity, slowly moves about in the water surface, in spy
It is acute that to acute stage, juvenile prawn physical weakness, shell softness, digestive tract is empty to have the pigmentation of redness without food on attached foot,
Especially uropodium, periproct, abdominal appendage, sometimes whole shrimp body body surface all become red.The sick shrimp step end of larger specification have moth it is disconnected,
Ulcerative phenomena, two antennas, tail fan, gastrointestinal tract redden, gastrointestinal tract swelling（Enteral has a small amount of food）, liver pancreas enlargement, change
In vain.The carapace of permeation parts disease shrimp, find muscle by it is original it is translucent become nebulousurine, especially abdomen end, like carapace and
Muscle separates shape.Occurs white area at the carapace of the sick shrimp in part, microscopy finds carapace and the diffusion of gastrointestinal wall tabletting erythrocyte.
Initial stage most of disease prawn head cuirass of catching an illness has white macula, has irregular black speck on the sick shrimp carapace of obstinate disease.For the virus
Prevention and treatment be increasingly becoming present aquaculture brainstrust focus of attention.And on the other hand for the treatment of disease of prawn
It is also contemplated that later stage food health problem.
Goal of the invention：In order to overcome the deficiencies in the prior art, the present invention to provide one kind and treat the drawing of prawn Fructus Persicae comprehensively
Pharmaceutical composition of syndrome virus disease and preparation method thereof.
Technical scheme：In order to solve above-mentioned technical problem, the invention provides a kind of preventing and treating prawn taura syndrome virus
The pharmaceutical composition of disease, is prepared from by the raw material of following parts by weight：30 ~ 40 parts of Radix Salviae Miltiorrhizae, 15 ~ 30 parts of Radix Rehmanniae, Radix Astragali
20 ~ 35 parts, 20 ~ 30 parts of Folium Isatidiss, 15 ~ 30 parts of Cortex Moutan, 20 ~ 35 parts of Herba Lycopi, 25 ~ 35 parts of Rhizoma Phragmitiss, 10 ~ 20 parts of Fructus Forsythiae.
It is prepared from by the raw material of following parts by weight：35 ~ 40 parts of Radix Salviae Miltiorrhizae, 20 ~ 30 parts of Radix Rehmanniae, 25 ~ 35 parts of Radix Astragali,
25 ~ 30 parts of Folium Isatidiss, 20 ~ 30 parts of Cortex Moutan, 30 ~ 35 parts of Herba Lycopi, 30 ~ 35 parts of Rhizoma Phragmitiss, 15 ~ 20 parts of Fructus Forsythiae.
It is prepared from by the raw material of following parts by weight：35 parts of Radix Salviae Miltiorrhizae, 20 parts of Radix Rehmanniae, 25 parts of Radix Astragali, Folium Isatidiss 25
Part, 20 parts of Cortex Moutan, 30 parts of Herba Lycopi, 30 parts of Rhizoma Phragmitiss, 15 parts of Fructus Forsythiae.
The preparation method of the pharmaceutical composition of described preventing and treating prawn taura syndrome virosiss, comprises the following steps：
1）Each crude drug is weighed by above-mentioned parts by weight, and crushed 450 mesh sieves, make powder；
2）The water of 25 times of powder weight will be added in powder after crushing, plus decoction obtains liquid in 60 minutes in the pot that is used as medicine
Medicine, stops working；
3）When being cooled to 32 DEG C, according to liquid medicine：Prawn feed=1:25 weight ratio, by prawn feed liquid medicine is immersed
In 40 minutes, and mixing and stirring makes the hybrid particles of medicine and feedstuff.
The particle diameter of the hybrid particles is 1.3 ~ 1.7mm.
The present invention provide the feeding method containing pharmaceutical composition made by above-mentioned raw materials be：In prawn taura syndrome
Aforementioned pharmaceutical compositions are continuously fed 35 ~ 45 days within 20 ~ 30 days before virosiss morbidity season, or at the initial stage of a disease will be upper
State pharmaceutical composition and continuously fed 45 ~ 55 days.
Beneficial effect：The drug regimen composition formula of the present invention is reasonable in design, and contained drug is low toxicity Chinese medicine, and the group
Contain antibacterial bacteriostatic Chinese medicine in compound, said composition has effectively prevented and treated prawn taura syndrome virosiss, the system that the present invention is provided
Preparation Method is simple, feed convenience, is adapted to large-scale production.
Specific embodiment
The present invention is further described with reference to embodiment.
Embodiment 1：
A kind of pharmaceutical composition of preventing and treating prawn taura syndrome virosiss, by the raw material preparation of following parts by weight
Into：30 parts of Radix Salviae Miltiorrhizae, 15 parts of Radix Rehmanniae, 20 parts of Radix Astragali, 20 parts of Folium Isatidiss, 15 parts of Cortex Moutan, 20 parts of Herba Lycopi, 25 parts of Rhizoma Phragmitiss, Fructus Forsythiae 10
Part.
The preparation method of the pharmaceutical composition of described preventing and treating prawn taura syndrome virosiss, comprises the following steps：
1）Each crude drug is weighed by above-mentioned parts by weight, and crushed 450 mesh sieves, make powder；
2）The water of 25 times of powder weight will be added in powder after crushing, plus decoction obtains liquid in 60 minutes in the pot that is used as medicine
Medicine, stops working；
3）When being cooled to 32 DEG C, according to liquid medicine：Prawn feed=1:25 weight ratio, by prawn feed liquid medicine is immersed
In 40 minutes, and mixing and stirring makes the hybrid particles of medicine and feedstuff.
The particle diameter of the hybrid particles is 1.3mm.
Embodiment 2：
A kind of pharmaceutical composition of preventing and treating prawn taura syndrome virosiss, by the raw material preparation of following parts by weight
Into：40 parts of Radix Salviae Miltiorrhizae, 30 parts of Radix Rehmanniae, 35 parts of Radix Astragali, 30 parts of Folium Isatidiss, 30 parts of Cortex Moutan, 35 parts of Herba Lycopi, 35 parts of Rhizoma Phragmitiss, Fructus Forsythiae 20
Part.
The preparation method of the pharmaceutical composition of described preventing and treating prawn taura syndrome virosiss, comprises the following steps：
1）Each crude drug is weighed by above-mentioned parts by weight, and crushed 450 mesh sieves, make powder；
2）The water of 25 times of powder weight will be added in powder after crushing, plus decoction obtains liquid in 60 minutes in the pot that is used as medicine
Medicine, stops working；
3）When being cooled to 32 DEG C, according to liquid medicine：Prawn feed=1:25 weight ratio, by prawn feed liquid medicine is immersed
In 40 minutes, and mixing and stirring makes the hybrid particles of medicine and feedstuff.
The particle diameter of the hybrid particles is 1.7mm.
Embodiment 3：
A kind of pharmaceutical composition of preventing and treating prawn taura syndrome virosiss, by the raw material preparation of following parts by weight
Into：35 parts of Radix Salviae Miltiorrhizae, 20 parts of Radix Rehmanniae, 25 parts of Radix Astragali, 25 parts of Folium Isatidiss, 20 parts of Cortex Moutan, 30 parts of Herba Lycopi, 30 parts of Rhizoma Phragmitiss, Fructus Forsythiae 15
Part.
The preparation method of the pharmaceutical composition of described preventing and treating prawn taura syndrome virosiss, comprises the following steps：
1）Each crude drug is weighed by above-mentioned parts by weight, and crushed 450 mesh sieves, make powder；
2）The water of 25 times of powder weight will be added in powder after crushing, plus decoction obtains liquid in 60 minutes in the pot that is used as medicine
Medicine, stops working；
3）When being cooled to 32 DEG C, according to liquid medicine：Prawn feed=1:25 weight ratio, by prawn feed liquid medicine is immersed
In 40 minutes, and mixing and stirring makes the hybrid particles of medicine and feedstuff.
The particle diameter of the hybrid particles is 1.5mm.
The pharmaceutical composition usage and consumption of any one of the embodiment of the present invention 1 ~ 3：In prawn taura syndrome virosiss
Aforementioned pharmaceutical compositions are continuously fed 35 ~ 45 days within 20 ~ 30 days before morbidity season, or at the initial stage of a disease by said medicine
Compositionss are continuously fed 45 ~ 55 days.
Feeding method：
1）, prevention：20 ~ 30 days before prawn taura syndrome virosiss morbidity season, when the shrimp pool is put into shrimp seedling, will
Aforementioned pharmaceutical compositions are continuously fed 40 days.
2）, treatment：When shrimp death occurs in the shrimp pool or stops eating, aforementioned pharmaceutical compositions are continuously fed 50 days.
Result of the test：After the prevention phase, there is not prawn death, prevention rate 100%.20 ~ 90 days after treatment phase, do not have
Have and shrimp death or phenomenon of stopping eating, cure rate 100% occurring.
The above is only the preferred embodiment of the present invention, it should be pointed out that：For those skilled in the art come
Say, under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be regarded as
Protection scope of the present invention.
Claims (1)
1. it is a kind of preventing and treating prawn taura syndrome virosiss pharmaceutical composition preparation method, described pharmaceutical composition is by weight
Number is prepared from the following materials, 30 ~ 40 parts of Radix Salviae Miltiorrhizae, 15 ~ 30 parts of Radix Rehmanniae, 20 ~ 35 parts of Radix Astragali, 20 ~ 30 parts of Folium Isatidiss, pellet
15 ~ 30 parts of skin, 20 ~ 35 parts of Herba Lycopi, 25 ~ 35 parts of Rhizoma Phragmitiss, 10 ~ 20 parts of Fructus Forsythiae, it is characterised in that the preventing and treating prawn Fructus Persicae draws comprehensive
The preparation method of the pharmaceutical composition of syndrome virus disease is comprised the following steps：
1）Each crude drug is weighed by above-mentioned parts by weight, and crushed 450 mesh sieves, make powder；
2）The water of 25 times of powder weight will be added in powder after crushing, plus decoction obtains liquid medicine in 60 minutes in the pot that is used as medicine, and puts out
Fire；
3）When being cooled to 32 DEG C, according to liquid medicine：Prawn feed=1:25 weight ratio, prawn feed is immersed 40 in liquid medicine
Minute, and mixing and stirring, make the hybrid particles of medicine and feedstuff；The particle diameter of the hybrid particles is 1.3 ~ 1.7mm.
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| CN201310342767.8A CN103463469B (en) | 2013-08-08 | 2013-08-08 | Prawn Taura syndrome virus disease treatment drug composition and preparation method thereof |
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| CN201310342767.8A CN103463469B (en) | 2013-08-08 | 2013-08-08 | Prawn Taura syndrome virus disease treatment drug composition and preparation method thereof |
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| CN103463469A CN103463469A (en) | 2013-12-25 |
| CN103463469B true CN103463469B (en) | 2017-04-19 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543589A (en) * | 2008-03-26 | 2009-09-30 | 北京大北农动物保健科技有限责任公司 | Compound pharmaceutical composition for curing virus diseases of animals and preparation method thereof |
| CN102139041A (en) * | 2010-10-31 | 2011-08-03 | 仙桃市魏氏生物工程有限责任公司 | Pharmaceutical composition for preventing and treating red body diseases of shrimps |
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2013
- 2013-08-08 CN CN201310342767.8A patent/CN103463469B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101543589A (en) * | 2008-03-26 | 2009-09-30 | 北京大北农动物保健科技有限责任公司 | Compound pharmaceutical composition for curing virus diseases of animals and preparation method thereof |
| CN102139041A (en) * | 2010-10-31 | 2011-08-03 | 仙桃市魏氏生物工程有限责任公司 | Pharmaceutical composition for preventing and treating red body diseases of shrimps |
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