CN103405512A - Chinese medicine granule for preventing and treating hemorrhage of grass carp, and preparation method thereof - Google Patents
Chinese medicine granule for preventing and treating hemorrhage of grass carp, and preparation method thereof Download PDFInfo
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Abstract
The invention provides a Chinese medicine granule for preventing and treating hemorrhage of grass carp, and a preparation method thereof. The Chinese medicine granule comprises the following ingredients in parts by weights: 2-4 parts of radix isatidis, 2-4 parts of corydalis bungeana, 2-4 parts of chrysanthemum, 1-2 parts of radix sophorae tonkinensis, 1-2 parts of common andrographis herb, 1-2 parts of Gentiana scabra and 1-2 parts of liquorice, and the Chinese medicine granule is prepared by a method comprising the steps of decocting and adding saccharose and starch. The Chinese medicine granule reasonably combines the traditional Chinese medicines, is obvious in effects of being antivirus and anti-inflammation and boosting immunity, thus providing an effective therapeutic medicament for the hemorrhage of grass carp; the Chinese medicine granule has the characteristics of being fast to take effect, and reliable in curative effect, and having no medicine residues and no toxic and side effects; the preparation method is simple and suitable for demand of large-scale industrial production.
Description
Technical field
The present invention relates to a kind of Chinese medicine granules and preparation method thereof, especially a kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp and preparation method thereof.
Background technology
The cause of disease of hemorrhagic disease of grass carp is GCRV, is again GCHV.The ill initial stage, sick fish loss of appetite, the body colour blackout, sick fish namely shows the bleeding of different parts subsequently.Muscle is point-like or the speckle shape is hemorrhage, the hemorrhage cerise that is of whole-body muscle when serious.Intestinal wall is cerise, the enteral empty because of hemorrhage and hyperemia.The Ctenopharyngodon idellus of main harm 2.5-15cm size, mortality rate is high, can reach more than 80%, and epidemic season is in late June to by the end of September, and be onset peak season August.For the hemorrhagic disease of grass carp present stage Western medicine antibiotic that adopt, treat more, although it is stricter that aquatic medicine is controlled, the antiviral Western medicine is forbidden, but Western medicine abuse of antibiotics situation is still very serious, the aggravation of virus variation speed, make the treatment difficulty of hemorrhagic disease of grass carp strengthen, the drug residue problem is more and more heavier, causes serious threat for the food safety problem.China's natural resources of Chinese medicinal materials is abundant, and by Chinese medicine is rationally screened and prescription, the first-selection as the treatment hemorrhagic disease of grass carp, will have very important production practices meaning.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp.
Another technical problem to be solved by this invention is to provide the preparation method of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp, by Radix Isatidis, Herba Corydalis Bungeanae, Flos Chrysanthemi, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Gentianae and Radix Glycyrrhizae, formed, by its parts by weight Radix Isatidis 2-4 part, Herba Corydalis Bungeanae 2-4 part, Flos Chrysanthemi 2-4 part, Radix Sophorae Tonkinensis 1-2 part, Herba Andrographis 1-2 part, Radix Gentianae 1-2 part, Radix Glycyrrhizae 1-2 part.
Preferably, the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp is obtained by following method:
(1) taking by weight Radix Isatidis 2-4 part, Herba Corydalis Bungeanae 2-4 part, Flos Chrysanthemi 2-4 part, Radix Sophorae Tonkinensis 1-2 part, Herba Andrographis 1-2 part, Radix Gentianae 1-2 part, Radix Glycyrrhizae 1-2 part is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.35-1.4, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
Preferably, the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, by its parts by weight Radix Isatidis 3-4 part, Herba Corydalis Bungeanae 3-4 part, Flos Chrysanthemi 2-3 part, Radix Sophorae Tonkinensis 1-1.5 part, Herba Andrographis 1.5-2 part, Radix Gentianae 1-2 part, Radix Glycyrrhizae 1.5-2 part.
Preferably, the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, by 3.5 parts of its parts by weight Radix Isatidis, 4 parts of Herba Corydalis Bungeanaes, 3 parts of Flos Chrysanthemis, 1 part of Radix Sophorae Tonkinensis, 1.5 parts of Herba Andrographis, 2 parts of Radix Gentianaes, 2 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, concrete preparation process is as follows:
(1) taking by weight Radix Isatidis 2-4 part, Herba Corydalis Bungeanae 2-4 part, Flos Chrysanthemi 2-4 part, Radix Sophorae Tonkinensis 1-2 part, Herba Andrographis 1-2 part, Radix Gentianae 1-2 part, Radix Glycyrrhizae 1-2 part is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.35-1.4, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
Above-mentioned relative density refers to the proportion of this filtrate.
The consumption of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, in the ratio of 5-10g/100kg body weight, to mix pharmaceutical chemistry, allows lymphogranuloma inguinale take, and being used in conjunction 3-5 days is a course for the treatment of.
The invention has the beneficial effects as follows:
The Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, by the Chinese medicine reasonable formula, the effect of antiviral, antiinflammatory, enhancing immunity is very remarkable, a kind of effective medicine of hemorrhagic disease of grass carp is provided for pisciculture, have instant effect, curative effect really, no drug residue, characteristics without any side effects; Its preparation method is simple, is applicable to the needs that large-scale industrial is produced.
The specific embodiment
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp, by Radix Isatidis, Herba Corydalis Bungeanae, Flos Chrysanthemi, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Gentianae and Radix Glycyrrhizae, formed, wherein, Radix Isatidis 3.5kg, Herba Corydalis Bungeanae 4kg, Flos Chrysanthemi 3kg, Radix Sophorae Tonkinensis 1kg, Herba Andrographis 1.5kg, Radix Gentianae 2kg, Radix Glycyrrhizae 2kg.
The preparation method of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, concrete preparation process is as follows:
(1) take Radix Isatidis 3.5kg, Herba Corydalis Bungeanae 4kg, Flos Chrysanthemi 3kg, Radix Sophorae Tonkinensis 1kg, Herba Andrographis 1.5kg, Radix Gentianae 2kg, Radix Glycyrrhizae 2kg is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.4, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
Embodiment 2
A kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp, by Radix Isatidis, Herba Corydalis Bungeanae, Flos Chrysanthemi, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Gentianae and Radix Glycyrrhizae, formed, wherein, Radix Isatidis 4kg, Herba Corydalis Bungeanae 2kg, Flos Chrysanthemi 2kg, Radix Sophorae Tonkinensis 2kg, Herba Andrographis 2kg, Radix Gentianae 2kg, Radix Glycyrrhizae 1kg.
The preparation method of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, concrete preparation process is as follows:
(1) take Radix Isatidis 4kg, Herba Corydalis Bungeanae 2kg, Flos Chrysanthemi 2kg, Radix Sophorae Tonkinensis 2kg, Herba Andrographis 2kg, Radix Gentianae 2kg, Radix Glycyrrhizae 1kg is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.35, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
Embodiment 3
A kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp, by Radix Isatidis, Herba Corydalis Bungeanae, Flos Chrysanthemi, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Gentianae and Radix Glycyrrhizae, formed, wherein, Radix Isatidis 2kg, Herba Corydalis Bungeanae 4kg, Flos Chrysanthemi 4kg, Radix Sophorae Tonkinensis 1kg, Herba Andrographis 1kg, Radix Gentianae 1kg, Radix Glycyrrhizae 2kg.
The preparation method of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, concrete preparation process is as follows:
(1) take Radix Isatidis 2kg, Herba Corydalis Bungeanae 4kg, Flos Chrysanthemi 4kg, Radix Sophorae Tonkinensis 1kg, Herba Andrographis 1kg, Radix Gentianae 1kg, Radix Glycyrrhizae 2kg is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.4, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
Embodiment 4
A kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp, by Radix Isatidis, Herba Corydalis Bungeanae, Flos Chrysanthemi, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Gentianae and Radix Glycyrrhizae, formed, wherein, Radix Isatidis 3kg, Herba Corydalis Bungeanae 4kg, Flos Chrysanthemi 3kg, Radix Sophorae Tonkinensis 1kg, Herba Andrographis 1.5kg, Radix Gentianae 1kg, Radix Glycyrrhizae 2kg.
The preparation method of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, concrete preparation process is as follows:
(1) take Radix Isatidis 3kg, Herba Corydalis Bungeanae 4kg, Flos Chrysanthemi 3kg, Radix Sophorae Tonkinensis 1kg, Herba Andrographis 1.5kg, Radix Gentianae 1kg, Radix Glycyrrhizae 2kg is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.38, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
Embodiment 5
A kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp, by Radix Isatidis, Herba Corydalis Bungeanae, Flos Chrysanthemi, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Gentianae and Radix Glycyrrhizae, formed, wherein, Radix Isatidis 4kg, Herba Corydalis Bungeanae 3kg, Flos Chrysanthemi 2kg, Radix Sophorae Tonkinensis 1.5kg, Herba Andrographis 2kg, Radix Gentianae 2kg, Radix Glycyrrhizae 1.5kg.
The preparation method of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, concrete preparation process is as follows:
(1) take Radix Isatidis 4kg, Herba Corydalis Bungeanae 3kg, Flos Chrysanthemi 2kg, Radix Sophorae Tonkinensis 1.5kg, Herba Andrographis 2kg, Radix Gentianae 2kg, Radix Glycyrrhizae 1.5kg is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.37, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
Embodiment 6
A kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp, by Radix Isatidis, Herba Corydalis Bungeanae, Flos Chrysanthemi, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Gentianae and Radix Glycyrrhizae, formed, wherein, Radix Isatidis 3.5kg, Herba Corydalis Bungeanae 3.5kg, Flos Chrysanthemi 2kg, Radix Sophorae Tonkinensis 1.5kg, Herba Andrographis 1.7kg, Radix Gentianae 1.5kg, Radix Glycyrrhizae 1.8kg.
The preparation method of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, concrete preparation process is as follows:
(1) take Radix Isatidis 3.5kg, Herba Corydalis Bungeanae 3.5kg, Flos Chrysanthemi 2kg, Radix Sophorae Tonkinensis 1.5kg, Herba Andrographis 1.7kg, Radix Gentianae 1.5kg, Radix Glycyrrhizae 1.8kg is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.4, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
The described Chinese crude drug of one of embodiment 1-6 is commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The described Chinese crude drug of embodiment 1-6 all meets " Chinese veterinary pharmacopoeia " version two ministerial standards in 2010.
The composition principle of Chinese medicine oral liquid of the present invention is: Radix Isatidis heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving in side; Herba Corydalis Bungeanae heat-clearing and toxic substances removing, removing heat from blood detumescence; The heat clearing away of chrysanthemum powder forimproving wind, suppressing the hyperactive liver improving eyesight; Radix Sophorae Tonkinensis heat-clearing and toxic substances removing, detumescence sore-throat relieving, expelling phlegm for arresting cough; Herba Andrographis heat-clearing and toxic substances removing, reducing swelling and alleviating pain; Radix Gentianae heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire; Radix Glycyrrhizae cushion toxicity, strong; All medicines share, and Synergistic, remarkably productive to the control hemorrhagic disease of grass carp mutually, especially adopts the described proportioning of embodiment 1, and the effect of antiviral, antiinflammatory, enhancing immunity is very remarkable, particularly is applicable to the treatment of hemorrhagic disease of grass carp.
The clinical trial example:
The consumption of the Chinese medicine granules of above-mentioned control hemorrhagic disease of grass carp, in the ratio of 5g/100kg body weight, to mix pharmaceutical chemistry, allows lymphogranuloma inguinale take, and being used in conjunction 3 days is a course for the treatment of.After oral, reach the purpose for the treatment of disease by intestinal absorption.
On July 26th, 2011, the 20000 tail Ctenopharyngodon idellus morbidities that Jiamusi foster Ctenopharyngodon idellus raiser in Heilungkiang raises, clinical symptoms: sick fish loss of appetite, the body colour blackout, hemorrhage around upper lower jaw and the gill cover, cut open in the visible intestinal of inspection congested, kidney has petechia, day mortality 30-40 tail.Be hemorrhagic disease of grass carp after diagnosing.Then with the described Chinese medicine granules of the embodiment of the present invention 1, treat, medication is after 5 hours, and the state of an illness is clearly better, and the health change color is obvious, and appetite increases, and mortality rate is by a day reduction, and after 3 days, mortality rate is 0, and sick fish is almost recovered.
Above-mentioned detailed description of this a kind of Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (5)
1. Chinese medicine granules of preventing and treating hemorrhagic disease of grass carp, it is characterized in that: by Radix Isatidis, Herba Corydalis Bungeanae, Flos Chrysanthemi, Radix Sophorae Tonkinensis, Herba Andrographis, Radix Gentianae and Radix Glycyrrhizae, formed, by its parts by weight Radix Isatidis 2-4 part, Herba Corydalis Bungeanae 2-4 part, Flos Chrysanthemi 2-4 part, Radix Sophorae Tonkinensis 1-2 part, Herba Andrographis 1-2 part, Radix Gentianae 1-2 part, Radix Glycyrrhizae 1-2 part.
2. the Chinese medicine granules of control hemorrhagic disease of grass carp according to claim 1 is characterized in that: obtained by following method:
(1) taking by weight Radix Isatidis 2-4 part, Herba Corydalis Bungeanae 2-4 part, Flos Chrysanthemi 2-4 part, Radix Sophorae Tonkinensis 1-2 part, Herba Andrographis 1-2 part, Radix Gentianae 1-2 part, Radix Glycyrrhizae 1-2 part is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.35-1.4, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
3. the Chinese medicine granules of control hemorrhagic disease of grass carp according to claim 1 and 2, is characterized in that: by its parts by weight Radix Isatidis 3-4 part, Herba Corydalis Bungeanae 3-4 part, Flos Chrysanthemi 2-3 part, Radix Sophorae Tonkinensis 1-1.5 part, Herba Andrographis 1.5-2 part, Radix Gentianae 1-2 part, Radix Glycyrrhizae 1.5-2 part.
4. the Chinese medicine granules of control hemorrhagic disease of grass carp according to claim 3, is characterized in that: by 3.5 parts of its parts by weight Radix Isatidis, 4 parts of Herba Corydalis Bungeanaes, 3 parts of Flos Chrysanthemis, 1 part of Radix Sophorae Tonkinensis, 1.5 parts of Herba Andrographis, 2 parts of Radix Gentianaes, 2 parts, Radix Glycyrrhizae.
5. the preparation method of the Chinese medicine granules of control hemorrhagic disease of grass carp claimed in claim 1 is characterized in that: concrete preparation process is as follows:
(1) taking by weight Radix Isatidis 2-4 part, Herba Corydalis Bungeanae 2-4 part, Flos Chrysanthemi 2-4 part, Radix Sophorae Tonkinensis 1-2 part, Herba Andrographis 1-2 part, Radix Gentianae 1-2 part, Radix Glycyrrhizae 1-2 part is raw material;
(2) to above-mentioned seven flavors, add the water of 4 times of amounts of medical material gross weight in Chinese medicines, decoct 2 times, decocted for the first time 120 minutes, decocted for the second time 100 minutes, collecting decoction, filter, and standing 12 hours of filtrate, get supernatant and concentrate, add ethanol to containing alcohol amount 60%(v/v), place, filter;
(3) filtrate is concentrated into to relative density 1.35-1.4, and reclaims ethanol, add sucrose and the agent of starch granulation in concentrated rear extractum, wherein, the mass ratio of concentrated rear extractum and sucrose, starch is 1:2:3.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104225176A (en) * | 2014-07-10 | 2014-12-24 | 天津植草园生物科技有限公司 | Botanical medicament for treating hemorrhagic diseases of grass carps and preparation method of botanical medicament |
CN107836598A (en) * | 2017-11-10 | 2018-03-27 | 贵州省思南县山野牧业有限公司 | A kind of feed addictive for treating hemorrhagic disease of grass carp and preparation method thereof |
CN115252681A (en) * | 2022-07-27 | 2022-11-01 | 江苏省淡水水产研究所 | Chinese herbal medicine composition for preventing carassius auratus gibelio overwintering syndrome as well as preparation and application thereof |
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2013
- 2013-08-29 CN CN2013103849260A patent/CN103405512A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104225176A (en) * | 2014-07-10 | 2014-12-24 | 天津植草园生物科技有限公司 | Botanical medicament for treating hemorrhagic diseases of grass carps and preparation method of botanical medicament |
CN107836598A (en) * | 2017-11-10 | 2018-03-27 | 贵州省思南县山野牧业有限公司 | A kind of feed addictive for treating hemorrhagic disease of grass carp and preparation method thereof |
CN115252681A (en) * | 2022-07-27 | 2022-11-01 | 江苏省淡水水产研究所 | Chinese herbal medicine composition for preventing carassius auratus gibelio overwintering syndrome as well as preparation and application thereof |
CN115252681B (en) * | 2022-07-27 | 2023-06-23 | 江苏省淡水水产研究所 | Chinese herbal medicine composition for preventing carassius auratus gibelio overwintering syndrome and preparation and application thereof |
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