CN103432294A - Traditional Chinese medicine oral liquid for treating prawn eye disease and preparation method thereof - Google Patents
Traditional Chinese medicine oral liquid for treating prawn eye disease and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine oral liquid for treating prawn eye disease and a preparation method thereof. The traditional Chinese medicine oral liquid comprises the following components according to parts by weight: 3-6 parts of honeysuckle, 1-2 parts of fructus forsythia, 2-4 parts of common andrographis herb, 1-2 parts of carpet bugle, 1-2 parts of jasmine, 1-2 parts of folium isatidis and 1-2 parts of liquorice. The traditional Chinese medicine oral liquid is prepared by decoction and comprises reasonable traditional Chinese medicine components, thus having obvious effects in antisepsis and anti-inflammation and enhancement of immunity, and being an effective medicine for treating prawn eye disease in the aquaculture industry. The oral liquid has the characteristics of having fast and real effect, having no medicine residual, being not easy in generation of drug resistance, and having no toxic or side effects; the preparation method is simple and is applicable to the requirement of large-scale industrial production.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid and preparation method thereof, especially a kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn and preparation method thereof.
Background technology
The cause of disease of the rotten oculopathy of prawn is non-zero 1 group cholera vibrio, sick shrimp action is dull, raise one's head and look, crawl at the bottom of pond or on pasture and water, frequently bubbles through the water column and does directionless mad trip, or float on the water surface, to roll from as axle, doing rotation, whole-body muscle becomes White-opalescent by water white transparency, and eyeball swelling, become brown by black, fester, the only remaining optic stalk had, mortality rate generally, in the 10%-30% left and right, can reach more than 80% when serious.For the rotten oculopathy of the prawn present stage Western medicine antibiotic that adopt, treated more, although it is stricter that aquatic medicine is controlled, but Western medicine abuse of antibiotics situation is still very serious, and because Resistant strain occurs very fast, make the treatment difficulty of the rotten oculopathy of prawn strengthen, the drug residue problem is more and more heavier, causes serious threat to the food safety problem.China's natural resources of Chinese medicinal materials is abundant, and by Chinese medicine is rationally screened and prescription, the first-selection as the rotten oculopathy for the treatment of prawn, will have very important production practices meaning.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn.
Another technical problem to be solved by this invention is to provide the preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn, by Flos Lonicerae, Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae, formed, by its parts by weight Flos Lonicerae 3-6 part, Fructus Forsythiae 1-2 part, Herba Andrographis 2-4 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1-2 part, Fructus Gardeniae 1-2 part, Folium Isatidis 1-2 part, Radix Glycyrrhizae 1-2 part.
Preferably, the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn is obtained by following method:
(1) taking by weight Flos Lonicerae 3-6 part, Fructus Forsythiae 1-2 part, Herba Andrographis 2-4 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1-2 part, Fructus Gardeniae 1-2 part, Folium Isatidis 1-2 part, Radix Glycyrrhizae 1-2 part is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.30-1.35, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
Preferably, the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, by its parts by weight Flos Lonicerae 5-6 part, Fructus Forsythiae 1-1.5 part, Herba Andrographis 2-3 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1.5-2 part, Fructus Gardeniae 1.5-2 part, Folium Isatidis 1.5-2 part, Radix Glycyrrhizae 1-1.5 part.
Preferably, the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, by 5 parts of its parts by weight Flos Loniceraes, 1.5 parts of Fructus Forsythiaes, 3 parts of Herba Andrographis, 2 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s, 1.5 parts of Fructus Gardeniaes, 1.5 parts of Folium Isatidiss, 1.5 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, concrete preparation process is as follows:
(1) taking by weight Flos Lonicerae 3-6 part, Fructus Forsythiae 1-2 part, Herba Andrographis 2-4 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1-2 part, Fructus Gardeniae 1-2 part, Folium Isatidis 1-2 part, Radix Glycyrrhizae 1-2 part is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.30-1.35, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
The preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, reclaim ethanol and refer to that the method by high temperature evaporation is recycled to the pure tank of storage by ethanol in described step (4), but the utilization of ethanol secondary, and after reclaiming, concentration of alcohol remains on more than 95%.
Above-mentioned relative density refers to the proportion of this supernatant.
The consumption of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, in the ratio of 3-5ml/100kg body weight, to mix pharmaceutical chemistry, makes prawn oral, and being used in conjunction 3-5 days is a course for the treatment of.
The invention has the beneficial effects as follows:
The Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, by the Chinese medicine reasonable formula, the effect of anti-inflammation, enhancing immunity is remarkable, for culture fishery provides effective medicine of the rotten oculopathy of a kind of prawn, have instant effect, curative effect really, no drug residue, be difficult for producing drug resistance, characteristics without any side effects; Its preparation method is simple, is applicable to the needs that large-scale industrial is produced.
The specific embodiment
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn, by Flos Lonicerae, Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae, formed, wherein, Flos Lonicerae 5kg, Fructus Forsythiae 1.5kg, Herba Andrographis 3kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 2kg, Fructus Gardeniae 1.5kg, Folium Isatidis 1.5kg, Radix Glycyrrhizae 1.5kg.
The preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, concrete preparation process is as follows:
(1) take Flos Lonicerae 5kg, Fructus Forsythiae 1.5kg, Herba Andrographis 3kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 2kg, Fructus Gardeniae 1.5kg, Folium Isatidis 1.5kg, Radix Glycyrrhizae 1.5kg is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.32, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
Embodiment 2
A kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn, by Flos Lonicerae, Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae, formed, wherein, Flos Lonicerae 6kg, Fructus Forsythiae 2kg, Herba Andrographis 2kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 2kg, Fructus Gardeniae 1kg, Folium Isatidis 1kg, Radix Glycyrrhizae 1kg.
The preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, concrete preparation process is as follows:
(1) take Flos Lonicerae 6kg, Fructus Forsythiae 2kg, Herba Andrographis 2kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 2kg, Fructus Gardeniae 1kg, Folium Isatidis 1kg, Radix Glycyrrhizae 1kg is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.30, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
Embodiment 3
A kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn, by Flos Lonicerae, Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae, formed, wherein, Flos Lonicerae 3kg, Fructus Forsythiae 1kg, Herba Andrographis 4kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1kg, Fructus Gardeniae 2kg, Folium Isatidis 2kg, Radix Glycyrrhizae 2kg.
The preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, concrete preparation process is as follows:
(1) take Flos Lonicerae 3kg, Fructus Forsythiae 1kg, Herba Andrographis 4kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1kg, Fructus Gardeniae 2kg, Folium Isatidis 2kg, Radix Glycyrrhizae 2kg is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.35, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
Embodiment 4
A kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn, by Flos Lonicerae, Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae, formed, wherein, Flos Lonicerae 5kg, Fructus Forsythiae 1.5kg, Herba Andrographis 3kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1.5kg, Fructus Gardeniae 2kg, Folium Isatidis 2kg, Radix Glycyrrhizae 1kg.
The preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, concrete preparation process is as follows:
(1) take Flos Lonicerae 5kg, Fructus Forsythiae 1.5kg, Herba Andrographis 3kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1.5kg, Fructus Gardeniae 2kg, Folium Isatidis 2kg, Radix Glycyrrhizae 1kg is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.33, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
Embodiment 5
A kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn, by Flos Lonicerae, Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae, formed, wherein, Flos Lonicerae 6kg, Fructus Forsythiae 1kg, Herba Andrographis 2kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 2kg, Fructus Gardeniae 1.5kg, Folium Isatidis 1.5kg, Radix Glycyrrhizae 1.5kg.
The preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, concrete preparation process is as follows:
(1) take Flos Lonicerae 6kg, Fructus Forsythiae 1kg, Herba Andrographis 2kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 2kg, Fructus Gardeniae 1.5kg, Folium Isatidis 1.5kg, Radix Glycyrrhizae 1.5kg is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.31, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
Embodiment 6
A kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn, by Flos Lonicerae, Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae, formed, wherein, Flos Lonicerae 5.5kg, Fructus Forsythiae 1.5kg, Herba Andrographis 2.3kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1.8kg, Fructus Gardeniae 1.6kg, Folium Isatidis 2kg, Radix Glycyrrhizae 1.5kg.
The preparation method of the Chinese medicine oral liquid of the rotten oculopathy of above-mentioned treatment prawn, concrete preparation process is as follows:
(1) take Flos Lonicerae 5.5kg, Fructus Forsythiae 1.5kg, Herba Andrographis 2.3kg, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1.8kg, Fructus Gardeniae 1.6kg, Folium Isatidis 2kg, Radix Glycyrrhizae 1.5kg is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.34, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
The described Chinese crude drug of one of embodiment 1-6 is commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
Reclaim ethanol described in one of embodiment 1-6 preparation method step (3) and refer to that the method by high temperature evaporation is recycled to ethanol in the pure tank of storage.
The described Chinese crude drug of embodiment 1-6 all meets " Chinese veterinary pharmacopoeia " version two ministerial standards in 2010.
The composition principle of Chinese medicine oral liquid of the present invention is: Flos Lonicerae heat-clearing and toxic substances removing, loose wind wind dispelling in side; Fructus Forsythiae heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation; Herba Andrographis heat-clearing and toxic substances removing, reducing swelling and alleviating pain; The Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) clearing away heat-fire, subduing swelling and detoxicating, anti-inflammation; Fructus Gardeniae eliminating fire and detoxication, clearing away heat and promoting diuresis; Folium Isatidis heat-clearing and toxic substances removing, blood cooling and ecchymoses removing; Radix Glycyrrhizae cushion toxicity, strong; All medicines share, and Synergistic, remarkably productive to the rotten oculopathy of prawn mutually, especially adopts the described proportioning of embodiment 1, and the effect of anti-inflammation, enhancing immunity is very remarkable, particularly are applicable to the control of the rotten oculopathy of prawn.
The clinical trial example:
The described Chinese medicine oral liquid of the embodiment of the present invention 1 is mixed to pharmaceutical chemistry in the ratio of 3ml/100kg body weight, make prawn oral, being used in conjunction 5 days is a course for the treatment of.Reach the purpose for the treatment of disease after oral by intestinal absorption.
On July 18th, 2012,200 mu of prawn morbidities that raise at certain culture of Penaeus vannamei family, Dongying area, clinical symptoms: sick shrimp is slow in action, frequently bubbles through the water column and does directionless mad trip.Whole-body muscle becomes White-opalescent by water white transparency, and eyeball swelling, become brown by black, festers, and mortality rate 50-100 every day tail, be diagnosed as the rotten oculopathy of prawn.Then with the described Chinese medicine oral liquid treatment of the embodiment of the present invention 1, medication is after 6 hours, and the state of an illness is clearly better, and eye swelling alleviates, and mortality rate reduces by sky, and after 5 days, mortality rate is 0, and sick shrimp is almost recovered.
Above-mentioned detailed description of this kind of Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (5)
1. a Chinese medicine oral liquid for the treatment of the rotten oculopathy of prawn, it is characterized in that: by Flos Lonicerae, Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae, formed, by its parts by weight Flos Lonicerae 3-6 part, Fructus Forsythiae 1-2 part, Herba Andrographis 2-4 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1-2 part, Fructus Gardeniae 1-2 part, Folium Isatidis 1-2 part, Radix Glycyrrhizae 1-2 part.
2. the Chinese medicine oral liquid of the rotten oculopathy for the treatment of according to claim 1 prawn is characterized in that: by following method, obtained:
(1) taking by weight Flos Lonicerae 3-6 part, Fructus Forsythiae 1-2 part, Herba Andrographis 2-4 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1-2 part, Fructus Gardeniae 1-2 part, Folium Isatidis 1-2 part, Radix Glycyrrhizae 1-2 part is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.30-1.35, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
3. the Chinese medicine oral liquid of the rotten oculopathy for the treatment of prawn according to claim 1 and 2, is characterized in that: by its parts by weight Flos Lonicerae 5-6 part, Fructus Forsythiae 1-1.5 part, Herba Andrographis 2-3 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1.5-2 part, Fructus Gardeniae 1.5-2 part, Folium Isatidis 1.5-2 part, Radix Glycyrrhizae 1-1.5 part.
4. the Chinese medicine oral liquid of the rotten oculopathy for the treatment of prawn according to claim 3, is characterized in that: by 5 parts of its parts by weight Flos Loniceraes, 1.5 parts of Fructus Forsythiaes, 3 parts of Herba Andrographis, 2 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s, 1.5 parts of Fructus Gardeniaes, 1.5 parts of Folium Isatidiss, 1.5 parts, Radix Glycyrrhizae.
5. the preparation method of the Chinese medicine oral liquid of the rotten oculopathy for the treatment of claimed in claim 1 prawn, it is characterized in that: concrete preparation process is as follows:
(1) taking by weight Flos Lonicerae 3-6 part, Fructus Forsythiae 1-2 part, Herba Andrographis 2-4 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 1-2 part, Fructus Gardeniae 1-2 part, Folium Isatidis 1-2 part, Radix Glycyrrhizae 1-2 part is raw material;
(2) water of 4 times of amounts of medical material gross weight will be added after above-mentioned Fructus Forsythiae, Herba Andrographis, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.), Fructus Gardeniae, Folium Isatidis and Radix Glycyrrhizae 6 flavor Chinese medicines mixing, decoct twice, decoct for the first time 120 minutes, add Flos Lonicerae when decocting by the 30th minute, decoct for the second time 100 minutes, merge decocting liquid twice, filter, standing 12 hours of filtrate, get supernatant concentration to relative density 1.30-1.35, obtains concentrated solution standby;
(3) add ethanol to containing alcohol, measuring 60%(v/v in the concentrated solution of step (2)), standing, filter, get supernatant;
(4), after supernatant in step (3) is carried out to the ethanol recovery, supernatant flowing steam 30 minutes under 100 ℃ of conditions, obtain.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105410346A (en) * | 2015-10-30 | 2016-03-23 | 广西中医药大学 | Cultured penaeus vannamei survival rate improving traditional Chinese medicine preparation and preparation method thereof |
| CN105434706A (en) * | 2016-01-18 | 2016-03-30 | 张嗣喜 | Traditional Chinese medicine composition for treating gill rote disease of fish |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105410346A (en) * | 2015-10-30 | 2016-03-23 | 广西中医药大学 | Cultured penaeus vannamei survival rate improving traditional Chinese medicine preparation and preparation method thereof |
| CN105434706A (en) * | 2016-01-18 | 2016-03-30 | 张嗣喜 | Traditional Chinese medicine composition for treating gill rote disease of fish |
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