CN102657724A - Traditional Chinese medicine oral liquid for preventing and treating chicken infectious bronchitis and preparation method thereof - Google Patents
Traditional Chinese medicine oral liquid for preventing and treating chicken infectious bronchitis and preparation method thereof Download PDFInfo
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- CN102657724A CN102657724A CN201210163923XA CN201210163923A CN102657724A CN 102657724 A CN102657724 A CN 102657724A CN 201210163923X A CN201210163923X A CN 201210163923XA CN 201210163923 A CN201210163923 A CN 201210163923A CN 102657724 A CN102657724 A CN 102657724A
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Abstract
The invention provides a traditional Chinese medicine oral liquid for preventing and treating chicken infectious bronchitis and a preparation method thereof. The traditional Chinese medicine oral liquid is prepared from, by weight, 2-4 parts of indigowoad root, 3-6 parts of indigo naturalis, 2-4 parts of almond, 2-4 parts of radix scutellariae, 1-2 parts of platycodon grandiflorum, 1-2 parts of gardenia, 1-2 parts of radix asteris, 1-2 parts of common coltsfoot and 2-4 parts of liquorice. The traditional Chinese medicine oral liquid for preventing and treating the chicken infectious bronchitis is prepared by decoction, and is a medicament which can prevent and treat the chicken infectious bronchitis effectively for chicken raising industry through reasonable composition of traditional Chinese medicines. In addition, the traditional Chinese medicine oral liquid has the advantages of quick and reliable effect, no residues, less proneness to cause generation of medicine resistance and no side effects, is the first choice to treat the chicken infectious bronchitis, is prepared by simple process, and can be in large-scale industrial production.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid and preparation method thereof, especially a kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken and preparation method thereof.
Background technology
The infectious bronchitis of chicken disease is a common diseases of chickens, and morbidity season is more common in Qiu Mozhi spring Mo, but the most serious with winter.Infectious bronchitis virus belongs to coronavirus, can make trachea produce specific lesions, and this disease sickness rate is high, and the mortality rate of chickling can reach more than 25%.The Western medicine antibiotics does not have obvious curative effects to primary disease, suppresses the later stage secondary infection only, and drug residue problem and chemical sproof problem long-term existence, is difficult for solving the serious threat food-safety problem.Therefore has very important production practices meaning through Chinese medicine rationally being screened and prescription, develop the Chinese medicine preparation that is used to prevent and treat infectious bronchitis of chicken.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken.
Another technical problem to be solved by this invention is to provide the method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken; Form by Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae, by 2～4 parts of its parts by weight Radix Isatidis, 3～6 parts of Indigo Naturaliss, 2～4 parts in Semen Armeniacae Amarum, 2～4 parts of Radix Scutellariaes, 1～2 part of Radix Platycodonis, 1～2 part of Fructus Gardeniae, 1～2 part of Radix Asteris, 1～2 part of Flos Farfarae, 2～4 parts in Radix Glycyrrhizae.
Preferably; The Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken is by 2～3.5 parts of its parts by weight Radix Isatidis, 5～6 parts of Indigo Naturaliss, 3～4 parts in Semen Armeniacae Amarum, 2.5～3.5 parts of Radix Scutellariaes, 1～2 part of Radix Platycodonis, 1～2 part of Fructus Gardeniae, 1～1.5 part of Radix Asteris, 1～2 part of Flos Farfarae, 3～3.5 parts in Radix Glycyrrhizae.
Preferably, the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken is by 3 parts of its parts by weight Radix Isatidis, 5 parts of Indigo Naturaliss, 3 parts in Semen Armeniacae Amarum, 3 parts of Radix Scutellariaes, 2 parts of Radix Platycodoniss, 2 parts of Fructus Gardeniaes, 1 part of Radix Asteris, 1.5 parts of Flos Farfaraees, 3.5 parts in Radix Glycyrrhizae.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken, concrete preparation process is following:
(1) taking by weighing Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae by above-mentioned parts by weight is raw material;
(2) above-mentioned nine flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 100 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.30～1.35; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Reclaim ethanol in the method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken, said step (2) and be meant that the method through high temperature evaporation is recycled to storage alcohol jar with ethanol, but the ethanol second use reclaims the back concentration of alcohol and remains on more than 95%.
Above-mentioned relative density is meant the proportion of this supernatant.
The consumption of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken for by the ratio mixing of 0.5-1% (v/v) in drinking water, let chicken freely drink, logotype 3～5 days was a course of treatment.Oral back reaches the purpose of treatment disease through intestinal absorption.
The invention has the beneficial effects as follows:
The Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken; With the Chinese medicine reasonable formula; For poultry husbandry provides a kind of effective medicine of preventing and treating infectious bronchitis of chicken; Have instant effect, curative effect really, no drug residue, be difficult for producing drug resistance, characteristics without any side effects, be the first-selection of treatment infectious bronchitis of chicken; Its preparation method is simple, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment technical scheme according to the invention is further described.
Embodiment 1
A kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken; Form by Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae, wherein Radix Isatidis 3kg, Indigo Naturalis 5kg, Semen Armeniacae Amarum 3kg, Radix Scutellariae 3kg, Radix Platycodonis 2kg, Fructus Gardeniae 2kg, Radix Asteris 1kg, Flos Farfarae 1.5kg, Radix Glycyrrhizae 3.5kg.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken, concrete preparation process is following:
(1) taking by weighing Radix Isatidis 3kg, Indigo Naturalis 5kg, Semen Armeniacae Amarum 3kg, Radix Scutellariae 3kg, Radix Platycodonis 2kg, Fructus Gardeniae 2kg, Radix Asteris 1kg, Flos Farfarae 1.5kg, Radix Glycyrrhizae 3.5kg is raw material;
(2) above-mentioned nine flavor Chinese medicines are mixed the water that the back adds medical material 4 times of amounts of gross weight (96kg), decoct twice, decocted 120 minutes for the first time, decocted 100 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.35; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 2
A kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken; Form by Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae, wherein Radix Isatidis 4kg, Indigo Naturalis 4kg, Semen Armeniacae Amarum 2kg, Radix Scutellariae 4kg, Radix Platycodonis 1.5kg, Fructus Gardeniae 1.5kg, Radix Asteris 2kg, Flos Farfarae 1kg, Radix Glycyrrhizae 4kg.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken, concrete preparation process is following:
(1) taking by weighing Radix Isatidis 4kg, Indigo Naturalis 4kg, Semen Armeniacae Amarum 2kg, Radix Scutellariae 4kg, Radix Platycodonis 1.5kg, Fructus Gardeniae 1.5kg, Radix Asteris 2kg, Flos Farfarae 1kg, Radix Glycyrrhizae 4kg is raw material;
(2) above-mentioned nine flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 100 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.30; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 3
A kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken; Form by Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae, wherein Radix Isatidis 2kg, Indigo Naturalis 6kg, Semen Armeniacae Amarum 3kg, Radix Scutellariae 3.5kg, Radix Platycodonis 2kg, Fructus Gardeniae 1kg, Radix Asteris 1.5kg, Flos Farfarae 2kg, Radix Glycyrrhizae 3kg.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken, concrete preparation process is following:
(1) taking by weighing Radix Isatidis 2kg, Indigo Naturalis 6kg, Semen Armeniacae Amarum 3kg, Radix Scutellariae 3.5kg, Radix Platycodonis 2kg, Fructus Gardeniae 1kg, Radix Asteris 1.5kg, Flos Farfarae 2kg, Radix Glycyrrhizae 3kg is raw material;
(2) above-mentioned nine flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 100 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.33; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 4
A kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken; Form by Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae, wherein Radix Isatidis 4kg, Indigo Naturalis 3kg, Semen Armeniacae Amarum 2.5kg, Radix Scutellariae 3.3kg, Radix Platycodonis 1.2kg, Fructus Gardeniae 1.7kg, Radix Asteris 2kg, Flos Farfarae 1.6kg, Radix Glycyrrhizae 4kg.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken, concrete preparation process is following:
(1) taking by weighing Radix Isatidis 4kg, Indigo Naturalis 3kg, Semen Armeniacae Amarum 2.5kg, Radix Scutellariae 3.3kg, Radix Platycodonis 1.2kg, Fructus Gardeniae 1.7kg, Radix Asteris 2kg, Flos Farfarae 1.6kg, Radix Glycyrrhizae 4kg is raw material;
(2) above-mentioned nine flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 100 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.32; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 5
A kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken; Form by Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae, wherein Radix Isatidis 3kg, Indigo Naturalis 4kg, Semen Armeniacae Amarum 4kg, Radix Scutellariae 2kg, Radix Platycodonis 1kg, Fructus Gardeniae 1kg, Radix Asteris 2kg, Flos Farfarae 2kg, Radix Glycyrrhizae 2kg.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken, concrete preparation process is following:
(1) taking by weighing Radix Isatidis 3kg, Indigo Naturalis 4kg, Semen Armeniacae Amarum 4kg, Radix Scutellariae 2kg, Radix Platycodonis 1kg, Fructus Gardeniae 1kg, Radix Asteris 2kg, Flos Farfarae 2kg, Radix Glycyrrhizae 2kg is raw material;
(2) above-mentioned nine flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 100 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.34; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
Embodiment 6
A kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken; Form by Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae, wherein Radix Isatidis 3.5kg, Indigo Naturalis 5kg, Semen Armeniacae Amarum 4kg, Radix Scutellariae 2.5kg, Radix Platycodonis 1kg, Fructus Gardeniae 2kg, Radix Asteris 1kg, Flos Farfarae 1kg, Radix Glycyrrhizae 3.5kg.
The method for preparing of the Chinese medicine oral liquid of above-mentioned control infectious bronchitis of chicken, concrete preparation process is following:
(1) taking by weighing Radix Isatidis 3.5kg, Indigo Naturalis 5kg, Semen Armeniacae Amarum 4kg, Radix Scutellariae 2.5kg, Radix Platycodonis 1kg, Fructus Gardeniae 2kg, Radix Asteris 1kg, Flos Farfarae 1kg, Radix Glycyrrhizae 3.5kg is raw material;
(2) above-mentioned nine flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 100 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.31; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
The said Chinese crude drug of one of embodiment 1-6 is the commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
Reclaim ethanol described in one of embodiment 1-6 method for preparing step (2) and be meant that the method through high temperature evaporation is recycled to ethanol in the storage alcohol jar.
The said Chinese crude drug of embodiment 1-6 all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2010.
The composition principle of Chinese medicine oral liquid according to the invention is: Radix Isatidis heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving in the side; Indigo Naturalis heat-clearing and toxic substances removing, removing heat from blood; Almond cough-relieving is relievingd asthma, loosening bowel to relieve constipation; The Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication; The Radix Platycodonis lung qi dispersing eliminates the phlegm, cool pharynx, evacuation of pus; The Fructus Gardeniae eliminating fire and detoxication, clearing away heat and promoting diuresis, removing heat from blood, hemostasis; Radix Asteris nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm; Flos Farfarae nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm; Radix Glycyrrhizae cushion toxicity, strong.All medicines share, and Synergistic is remarkably productive to the control infectious bronchitis of chicken each other, especially adopts embodiment 1 said proportioning, and the effect of heat-clearing and toxic substances removing, removing heat from the lung and dissipating phlegm is very remarkable, particularly is fit to the control of infectious bronchitis of chicken.
The clinical trial example:
With the embodiment of the invention 1 said Chinese medicine oral liquid in the ratio mixing of 1% (v/v) in drinking-water, let chicken freely drink, logotype 3 days, oral back reaches the purpose of treatment disease through intestinal absorption.
On November 12nd, 2010,3000 chickling morbidities that certain specialist of raising chickens of Black Hills, Liaoning area raises, clinical symptoms: sick chicken rhinorrhea, shed tears, swelling of the nose expands, cough, sneeze, stretch neck and dehisce to breathe, and hears obviously hoarse cry night.Drop-head closes order, vertical wing squeezes heap, inappetence, the increase of drink desire, and day mortality 20-30 only.Be diagnosed as infectious bronchitis of fowl.Satisfy with the embodiment of the invention 1 said Chinese medicine oral liquid and treat, medication is after 3 hours, and the refreshing state of sick chicken essence is clearly better, and cough, sneeze symptom obviously alleviate, and mortality rate is by a day reduction, and mortality rate is zero after 3 days, and sick chicken is almost recovered.
Above-mentioned detailed description of this a kind of Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (4)
1. Chinese medicine oral liquid of preventing and treating infectious bronchitis of chicken; It is characterized in that: form by Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae, by 2～4 parts of its parts by weight Radix Isatidis, 3～6 parts of Indigo Naturaliss, 2～4 parts in Semen Armeniacae Amarum, 2～4 parts of Radix Scutellariaes, 1～2 part of Radix Platycodonis, 1～2 part of Fructus Gardeniae, 1～2 part of Radix Asteris, 1～2 part of Flos Farfarae, 2～4 parts in Radix Glycyrrhizae.
2. the Chinese medicine oral liquid of control infectious bronchitis of chicken according to claim 1 is characterized in that: by 2～3.5 parts of its parts by weight Radix Isatidis, 5～6 parts of Indigo Naturaliss, 3～4 parts in Semen Armeniacae Amarum, 2.5～3.5 parts of Radix Scutellariaes, 1～2 part of Radix Platycodonis, 1～2 part of Fructus Gardeniae, 1～1.5 part of Radix Asteris, 1～2 part of Flos Farfarae, 3～3.5 parts in Radix Glycyrrhizae.
3. the Chinese medicine oral liquid of control infectious bronchitis of chicken according to claim 1 and 2 is characterized in that: by 3 parts of its parts by weight Radix Isatidis, 5 parts of Indigo Naturaliss, 3 parts in Semen Armeniacae Amarum, 3 parts of Radix Scutellariaes, 2 parts of Radix Platycodoniss, 2 parts of Fructus Gardeniaes, 1 part of Radix Asteris, 1.5 parts of Flos Farfaraees, 3.5 parts in Radix Glycyrrhizae.
4. the method for preparing of the Chinese medicine oral liquid of the described control infectious bronchitis of chicken of one of claim 1-3 is characterized in that: concrete preparation process is following:
(1) taking by weighing Radix Isatidis, Indigo Naturalis, Semen Armeniacae Amarum, Radix Scutellariae, Radix Platycodonis, Fructus Gardeniae, Radix Asteris, Flos Farfarae and Radix Glycyrrhizae by above-mentioned parts by weight is raw material;
(2) above-mentioned nine flavor Chinese medicines are mixed the water that the back adds 4 times of amounts of medical material gross weight, decoct twice, decocted 120 minutes for the first time, decocted 100 minutes for the second time; Merge decocting liquid twice, filter, filtrating was left standstill 12 hours, and getting supernatant concentration to relative density is 1.30～1.35; Add dehydrated alcohol to containing alcohol amount 60% (v/v), place, filter, reclaim ethanol; Embedding, 100 ℃ of flowing steams 30 minutes promptly get.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456362A (en) * | 2015-12-23 | 2016-04-06 | 青岛农业大学 | Mixture for treating chicken infectious bronchitis and preparation method thereof |
| CN106266507A (en) * | 2016-11-15 | 2017-01-04 | 中悦民安（北京）科技发展有限公司 | A kind of medicine treating infectious bronchitis of chicken and preparation method thereof |
| CN106421322A (en) * | 2016-11-15 | 2017-02-22 | 中悦民安（北京）科技发展有限公司 | Traditional Chinese medicine composition capable of preventing and treating infectious bronchitis of chickens and preparation method of traditional Chinese medicine composition |
-
2012
- 2012-05-23 CN CN201210163923XA patent/CN102657724A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105456362A (en) * | 2015-12-23 | 2016-04-06 | 青岛农业大学 | Mixture for treating chicken infectious bronchitis and preparation method thereof |
| CN105456362B (en) * | 2015-12-23 | 2020-12-04 | 青岛农业大学 | Mixture for treating infectious bronchitis of chicken and preparation method thereof |
| CN106266507A (en) * | 2016-11-15 | 2017-01-04 | 中悦民安（北京）科技发展有限公司 | A kind of medicine treating infectious bronchitis of chicken and preparation method thereof |
| CN106421322A (en) * | 2016-11-15 | 2017-02-22 | 中悦民安（北京）科技发展有限公司 | Traditional Chinese medicine composition capable of preventing and treating infectious bronchitis of chickens and preparation method of traditional Chinese medicine composition |
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Application publication date: 20120912 |