CN103070993A - Traditional Chinese medicine composition for treating respiratory disease of livestock and poultry and feed of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating respiratory disease of livestock and poultry and feed of traditional Chinese medicine composition Download PDF

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Publication number
CN103070993A
CN103070993A CN2013100373905A CN201310037390A CN103070993A CN 103070993 A CN103070993 A CN 103070993A CN 2013100373905 A CN2013100373905 A CN 2013100373905A CN 201310037390 A CN201310037390 A CN 201310037390A CN 103070993 A CN103070993 A CN 103070993A
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China
Prior art keywords
herba
chinese medicine
livestock
medicine composition
respiratory disease
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CN2013100373905A
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Chinese (zh)
Inventor
卢贵梅
刘澜
葛冰
杜继红
莫云
葛代兴
丛日刚
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Shaoshan Dabeinong Animal Midicinal Co Ltd
BEIJING DABEINONG ANIMAL HEALTH TECHNOLOGY Co Ltd
Beijing Dabeinong Technology Group Co Ltd
Original Assignee
Shaoshan Dabeinong Animal Midicinal Co Ltd
BEIJING DABEINONG ANIMAL HEALTH TECHNOLOGY Co Ltd
Beijing Dabeinong Technology Group Co Ltd
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Application filed by Shaoshan Dabeinong Animal Midicinal Co Ltd, BEIJING DABEINONG ANIMAL HEALTH TECHNOLOGY Co Ltd, Beijing Dabeinong Technology Group Co Ltd filed Critical Shaoshan Dabeinong Animal Midicinal Co Ltd
Priority to CN2013100373905A priority Critical patent/CN103070993A/en
Publication of CN103070993A publication Critical patent/CN103070993A/en
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry

Abstract

The invention discloses a traditional Chinese medicine composition for treating a respiratory disease of livestock and poultry and an application in feed. The traditional Chinese medicine composition comprises an active ingredient, wherein the active ingredient is prepared from spanishneedles herb, centella asiatlca urban, herba commelinae, taraxacum, mulberry leaf, radix isatidis, blackberrylily rhizome and herba cirsii. The traditional Chinese medicine composition can be used for treating respiratory infection of the livestock and poultry effectively, and has functions of preventing the infection, recovering a liver function and promoting regeneration of liver cells. The composition is extensive in raw material source, and has the advantages of safety, environmental protection, simple preparation process, low production cost, obvious medicine effect, and the like.

Description

Chinese medicine composition and the feedstuff thereof for the treatment of livestock and birds respiratory disease
Technical field
The invention belongs to field of veterinary and field of fodder, relate to a kind of the treat Chinese medicine composition of livestock and birds respiratory disease and the application in the feedstuff.
Background technology
At present, the M ﹠ M of the respiratory tract disease of poultry is all rising year by year, becomes a large problem of China's livestock and poultry breeding industry.The case of examining the livestock and birds respiratory disease that most local veterinary sees and treat patients according to accent is about 40-80 family weekly, the respiratory tract infection of poultry, eyelid are swollen, cough, egg production descend, the case of the excrement of having loose bowels increases gradually, the respiratory tract disease case of domestic animal is also in cumulative year after year, and because more than the pathogenic factor of respiratory tract disease, clinical treatment has certain difficulty and uncertainty, therapeutic effect is unsatisfactory, the use amount that increases chemicals can cause the clinical drug-resistant problem again, and the safety of animal food is also had considerable influence.
It has the dual function of medicine and nutrition Chinese herbal medicine, in the control livestock and birds respiratory disease, also can be animal some corresponding nutrient substance are provided.Chinese herbal medicine belongs to pure natural substance, aboundresources, cheap, have noresidue or low-residual, toxic and side effects little, do not produce the characteristics such as drug resistance.Therefore, Chinese herbal medicine instead of chemical medicine is prevented and treated livestock and birds respiratory disease and have extremely important meaning.
Summary of the invention
The object of the present invention is to provide a kind of low cost, good effect, drug residue free, be used for the treatment of the Chinese medicine composition of livestock and birds respiratory disease.
Another object of the present invention provides the preparation method of the Chinese medicine composition that is used for the treatment of livestock and birds respiratory disease.
The invention provides a kind of Chinese medicine composition that is used for the treatment of livestock and birds respiratory disease, contain active component, described active component is made by Herba Bidentis Bipinnatae, Herba Calthae Membranaceae, Herba Commelinae, Herba Taraxaci, Folium Mori, Radix Isatidis, Rhizoma Belamcandae and Herba Cirsii.
Wherein, described active component is made by Herba Bidentis Bipinnatae 10-30 part, Herba Calthae Membranaceae 15-20 part, Herba Commelinae 10-20 part, Herba Taraxaci 5-20 part, Folium Mori 10-20 part, Radix Isatidis 5-15 part, Rhizoma Belamcandae 6-15 part, Herba Cirsii 5-25 part.
Further, described active component is made by Herba Bidentis Bipinnatae 15-25 part, Herba Calthae Membranaceae 15-20 part, Herba Commelinae 12-18 part, Herba Taraxaci 10-15 part, Folium Mori 12-18 part, Radix Isatidis 7-14 part, Rhizoma Belamcandae 8-13 part, Herba Cirsii 10-20 part.
Further, described active component is made by 15 parts of 25 parts of Herba Bidentis Bipinnatae, 18 parts of Herba Calthae Membranaceaes, 15 parts of Herba Commelinaes, 12 parts of Herba Taraxacis, 15 parts on Folium Mori, 10 parts of Radix Isatidiss, 10 parts of Rhizoma Belamcandae, Herba Cirsii.
The present invention also provides the described preparation method that is used for the treatment of the Chinese medicine composition of livestock and birds respiratory disease, and it comprises the steps:
(1) takes by weighing by weight ratio each medicine material;
(2) will claim each medicine material maybe will claim after pulverizing, sieving each medicine material through water or alcohol extraction, concentrated after, add again adjuvant or complementary composition that pharmacy can be used, be prepared from.
The dosage form of the Chinese medicine that is used for the treatment of livestock and birds respiratory disease that wherein, above-mentioned preparation method makes can be: powder, pre-mixing agent, powder, granule, oral liquid or injection.
Each drug component in the Chinese medicine of the present invention and consumption thereof be to control principle according to the dialectical opinion of Chinese veterinarian's prescription, gets by repeatedly practising in a large number.Medicine of the present invention has heat-clearing and toxic substances removing, and the functions such as antiinflammatory, recovery liver function, promotion liver cell regeneration cure mainly livestock and birds respiratory disease.Chinese medicine of the present invention can be used for preparing the medicine of livestock and birds respiratory disease.
Chinese medicine of the present invention also can be used for preparation and promotes the liver cell regeneration medicine.
Chinese medicine of the present invention also can add in the feedstuff, for the preparation of the feedstuff of poultry resisting respiratory tract disease, stimulated hepatic cell regeneration.
The present invention is at advantage and the beneficial effect of the Chinese medicine composition that is used for the treatment of livestock and birds respiratory disease, stimulated hepatic cell regeneration:
(1) the dialectical combined effect of controlling of executing of Chinese medicine performance Chinese medicinal formulae of the present invention, good effect, instant effect, treating both the principal and secondary aspects of a disease can be used for preventing and treating livestock and birds respiratory disease, have the characteristics such as preparation technology is simple, with low cost, easy to use;
(2) medicine of the present invention has solved the problems such as the livestock and birds respiratory disease cause of disease complicated and changeable, hepatic insufficiency, and to growth of animals or poultry and the positive role of having improved food conversion ratio, but Effective Raise poultry autoimmunity prevents the generation of livestock and birds respiratory disease;
(3) clinical problem that produces of the medicine of the present invention drug residue having avoided present chemicals to use bringing and drug resistance has ensured animal food safety and Environmental security;
(4) Chinese medicine of the present invention adopts the modern pharmaceutical technology to be prepared, and uses modern means of science and technology that Effective Component of Chinese Medicine is carried out qualitative and quantitative detection, and constant product quality, controlled has the stronger market competitiveness.
The specific embodiment
Following examples are used for explanation the present invention, but are not used for limiting the scope of the invention.
Embodiment 1 medicine preparation of the present invention and use
(1) take by weighing the raw material that contains following weight:
30 parts of Herba Bidentis Bipinnatae, 20 parts of Herba Calthae Membranaceaes, 20 parts of Herba Commelinaes, 20 parts of Herba Taraxacis, 20 parts on Folium Mori, 15 parts of Radix Isatidiss, 15 parts of Rhizoma Belamcandae, 25 parts of Herba Cirsiis
(2) with claim in the step (1) each weight crude drug pulverize, sieve after, fully be mixed with into powder.
(3) drug use method of the present invention: respiratory tract disease, mixed feeding: domestic animal, every 1kg feedstuff adds Chinese medicine 10g of the present invention, is used in conjunction 7.Poultry, the 1kg feedstuff adds Chinese medicine 15g of the present invention, is used in conjunction 7.
Embodiment 2 medicine preparation of the present invention and uses
(1) take by weighing the raw material that contains following weight:
10 parts of Herba Bidentis Bipinnatae, 15 parts of Herba Calthae Membranaceaes, 10 parts of Herba Commelinaes, 5 parts of Herba Taraxacis, 10 parts on Folium Mori, 5 parts of Radix Isatidiss, 6 parts of Rhizoma Belamcandae, 5 parts of Herba Cirsiis
(2) with claim in the step (1) each weight proportion crude drug pulverize after, after with ethanol the Herba Bidentis Bipinnatae medical material being soaked 2 hours first, alcohol reflux 2 times, each 2 hours, medicine with all the other components of distilled water immersion extracted 2 times after 0.5 hour again, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate also is condensed into the thick paste shape, add at last appropriate amount of starch and dextrin (or other adjuvant), mix homogeneously is made soft material, granulates, oven dry namely is prepared into granule (every 1g is equivalent to crude drug in whole 2g).
(3) drug use method of the present invention: respiratory tract disease, mixed drink: domestic animal, every 1L water adds medicine 1.5g of the present invention, freely drinks, and is used in conjunction 7.Poultry, every 1L water adds medicine 8.0g of the present invention, freely drinks, and is used in conjunction 7.
Embodiment 3 medicine preparation of the present invention and uses
(1) take by weighing the raw material that contains following weight:
15 parts of Herba Bidentis Bipinnatae, 15 parts of Herba Calthae Membranaceaes, 12 parts of Herba Commelinaes, 10 parts of Herba Taraxacis, 12 parts on Folium Mori, 7 parts of Radix Isatidiss, 8 parts of Rhizoma Belamcandae, 10 parts of Herba Cirsiis
(2) with claim in the step (1) each weight proportion crude drug pulverize after, with ethanol medical material is soaked 2 hours first after, alcohol reflux 2 times, each 2 hours, merging filtrate also was condensed into the thick paste shape; Filtering residue is used water extraction 2 times again, extracts 2.5 hours for the first time, extracts 1.5 hours for the second time, filters, and merging filtrate also is condensed into the thick paste shape; Merge extractum, add at last appropriate amount of starch and dextrin (or other adjuvant), mix homogeneously, oven dry is pulverized, and namely is prepared into powder (every 1g is equivalent to crude drug in whole 1g).
(3) drug use method of the present invention: respiratory tract disease, mixed feeding: domestic animal, every 1kg feedstuff adds medicine 10g of the present invention, is used in conjunction 7.The every 1kg feedstuff of poultry adds medicine 10g of the present invention, is used in conjunction 7.
Embodiment 4 medicine preparation of the present invention and uses
(1) take by weighing the raw material that contains following weight:
25 parts of Herba Bidentis Bipinnatae, 20 parts of Herba Calthae Membranaceaes, 18 parts of Herba Commelinaes, 15 parts of Herba Taraxacis, 18 parts on Folium Mori, 14 parts of Radix Isatidiss, 13 parts of Rhizoma Belamcandae, 20 parts of Herba Cirsiis.
(2) with claim in the step (1) each weight proportion crude drug pulverize after, after water soaks 1-2 hour with medical material, then decoct with high heat to boiling, decocted 30 minutes with the temperature fire again, filter, filtering residue adds water with slow fire boiling twice, each 1 hour.Merging filtrate, adding ethanol ethanol content to the filtrate after filtrate is concentrated is 70%, filters, and filtrate recycling ethanol is concentrated into every 1ml and is equivalent to crude drug in whole 2g, and filtration, embedding, sterilization namely are prepared into oral liquid.
(3) drug use method of the present invention: respiratory tract disease, mixed drink: domestic animal, every 1L water adds medicine 1.5ml of the present invention, freely drinks, and is used in conjunction 7.Poultry, every 1L water adds medicine 1.0ml of the present invention, freely drinks, and is used in conjunction 7
Embodiment 5 medicine preparation of the present invention and uses
(1) take by weighing the raw material that contains following weight:
25 parts of Herba Bidentis Bipinnatae, 18 parts of Herba Calthae Membranaceaes, 15 parts of Herba Commelinaes, 12 parts of Herba Taraxacis, 15 parts on Folium Mori, 10 parts of Radix Isatidiss, 10 parts of Rhizoma Belamcandae, 15 parts of Herba Cirsiis.
(2) with claim in the step (1) each weight proportion crude drug pulverize after, after water soaks 1-2 hour with medical material, then decoct to boiling with high heat, used again slow fire boiling 30 minutes, filter, filtering residue was with slow fire boiling twice, each 1 hour.Merging filtrate, adding ethanol ethanol content to the filtrate after filtrate is concentrated is 70%, filters, and filtrate recycling ethanol is concentrated into every 1ml and is equivalent to crude drug in whole 1g, and cold preservation, filtration, fine straining, embedding, sterilization namely are prepared into injection.
(3) drug use method of the present invention: respiratory infection diseases, intramuscular injection, each every 1kg body weight, domestic animal 0.1-0.2ml/kg, poultry 0.05-0.1ml/kg 1 time on the one, is used in conjunction 7.
For showing medicine of the present invention to poultry upper respiratory disease and stimulated hepatic cell regeneration effect, medicine of the present invention is carried out the clinical observation on the therapeutic effect test, below further set forth the beneficial effect of medicine of the present invention by test example.
Test example 1
On December 10th, 2011, Sichuan Province buys on the Luzhou City pig farm 250 of piglets, about body weight 18-20 kilogram, raise after 7 days, the part pig occurs,, loss of appetite depressed, crowded together by thick unrest of hair, eyelet pastiness, fervescence to 40 ℃~41.5 ℃, spirit, rapid breathing, dyspnea, palor or jaundice etc. show as the congenital symptom such as tremble of diarrhoea, cough and pigling sometimes, and the process pathologic finding is diagnosed as the upper respiratory tract infection disease.132 ill sick pigs are divided into 7 groups for examination.
Test grouping and administration: test is divided into 7 groups, and test 1 group and adopt embodiment 1 preparation, the mixed feeding administration, the per kilogram feedstuff adds Chinese medicine 10g of the present invention; Test 2 groups and adopt embodiment 2 preparations, the administration of mixed drink, every 1L water adds Chinese medicine 1.5g of the present invention, freely drinks; Test 3 groups and adopt embodiment 3 preparations, the mixed feeding administration, the per kilogram feedstuff adds Chinese medicine 10g of the present invention; Test 4 groups and adopt embodiment 4 preparations, the administration of mixed drink, every 1L water adds Chinese medicine 1.5ml of the present invention, freely drinks; Test 5 groups and adopt embodiment 5 preparations, intramuscular administration; Good group of pestilence larynx adopts 10% pestilence larynx good, intramuscular administration; The not administration of blank group; All the other each groups are used in conjunction 7.Continue after the off-test to observe 14, statistical results see Table 1.
Table 1 Chinese medicine composition of the present invention is added up the porcine respiratory disease curative effect
Result of the test shows: compare with the blank group, 6 test group all have significant curative effect to porcine respiratory disease; Compare with good group of pestilence larynx, 5 groups of medicine of the present invention will be got well respiratory tract infection of pigs diseases prevention and treatment effect, and are wherein best to test 5 groups of curative effects.
Test example 2
In November, 2011 the Dali chicken house 1000 chickens, the part chicken occurs that respiratory tract infection, eyelid are swollen, cough, egg production descend, the case of the excrement of having loose bowels increases gradually.Clinical diagnosis is respiratory disease of chicken.Selecting wherein, 160 chickens of serious symptom are divided into 4 groups for examination.Test grouping and administration: test is divided into 4 groups, and test 1 group and adopt embodiment 3 preparations, the mixed feeding administration, the per kilogram feedstuff adds Chinese medicine 10g of the present invention; Test 2 groups and adopt embodiment 5 preparations, drug administration by injection, 0.1ml/kg body weight; Test 3 groups and adopt Amoxicillin Sodium, the mixed feeding administration, the per kilogram feedstuff adds Amoxicillin Sodium powder 5g; The not administration of blank group; All the other each groups are used in conjunction 7.Continue after the off-test to observe 2, statistical results see Table 2.
Table 2 Chinese medicine composition of the present invention is added up the respiratory disease of chicken curative effect
Result of the test shows: medicine of the present invention and Amoxicillin Sodium have good prevention effect to respiratory disease of chicken, and curative effect of medication of the present invention is slightly better than Amoxicillin Sodium.
Test example 3
In March, 2012, breast appears in the chicken of Guangdong chicken house, and to show as spirit depressed, and feather pine disorderly, wing is sagging, and loss of appetite is arranged yellow, white, green feces, snore, cough, dyspnea, ataxia, shed tears, eyelid swelled, cockscomb be blue, laying rate descends, degradation under the eggshell quality.Clinical diagnosis is respiratory disease of chicken, selects 240 of the sick chickens that wherein state of an illness is more serious, is divided into 4 test group.Test 1 group and adopt embodiment 1 preparation, the mixed feeding administration, the per kilogram feedstuff adds Chinese medicine 10g of the present invention; Test 2 groups and adopt embodiment 2 preparations, the mixed feeding administration, the per kilogram feedstuff adds Chinese medicine 10g of the present invention; Test 3 groups and adopt the administration of ribavirin powder mixed feeding, the per kilogram feedstuff adds ribavirin powder 5g; The blank group is not added any medicine, the not administration of blank group; All the other each groups are used in conjunction 7.Continue after the off-test to observe 4, statistical results see Table 3.
Table 3 Chinese medicine composition of the present invention is to the curative effect statistics of respiratory disease of chicken
Result of the test shows: with blank group medicine of the present invention and ribavirin group respiratory disease of chicken is had good prevention effect, curative effect of medication of the present invention is slightly better than ribavirin.
Test example 4
Available from Beijing dimension tonneau China laboratory animal company limited 40 Kunming kind white mice 20~25g, be divided at random four groups, 10 every group, half and half, three group of male and female are with 56 degree Red Star strong, colourless liquor distilled from sorghum 0.15ml/10g body weight gavages, every day 2 times, midfeather 1 hour in 1 week of gavage, is set up three groups of liver injury models.Other one group compares, and gavages isopyknic cold boiled water, and equal conditions is raised a week.Get the murine liver tissue section with a group model group, observe under the light microscopic, fatty liver has all appearred in all mices of model group, and alcoholic hepatitis has appearred in the mice more than 90%; As seen, hepatocyte diminishes under the Electronic Speculum, examines irregularly, and Cytoplasm is loose, visible a large amount of fat drop cavitys not of uniform size and the Mallory body of thread arrangement in the Cytoplasm.All the other 20 5 do not process, the normal raising.Remain 15 with medicine embodiment of the present invention 4 mixed drink administrations, every 1L water adds Chinese medicine 1.0ml of the present invention, after 2 weeks of feeding continuously.Put to death, get the murine liver tissue section, 5 mices that do not take medicine of the present invention are raised in the process in 2 weeks dead 3, do and check under the hepatic tissue section light microscopic and still have fatty liver for remaining 2.Check under the Electronic Speculum that still as seen hepatocyte diminishes, examine irregularly that Cytoplasm is loose, as seen in a large number fat drop cavitys not of uniform size and the Mallory body of thread arrangement in the Cytoplasm.Check under 15 mice light microscopics of medicine of the present invention and the Electronic Speculum all without unusually and taken, close with the hepatic tissue section of the mice that does not have gavage Chinese liquor, show that medicine of the present invention can recover liver function, be conducive to hepatocellular regeneration.
The above only is preferred implementation of the present invention; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the technology of the present invention principle; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (9)

1. a Chinese medicine composition that is used for the treatment of livestock and birds respiratory disease contains active component, and described active component is made by Herba Bidentis Bipinnatae, Herba Calthae Membranaceae, Herba Commelinae, Herba Taraxaci, Folium Mori, Radix Isatidis, Rhizoma Belamcandae and Herba Cirsii.
2. the Chinese medicine composition that is used for the treatment of livestock and birds respiratory disease according to claim 1, it is characterized in that described active component is made by Herba Bidentis Bipinnatae 10-30 part, Herba Calthae Membranaceae 15-20 part, Herba Commelinae 10-20 part, Herba Taraxaci 5-20 part, Folium Mori 10-20 part, Radix Isatidis 5-15 part, Rhizoma Belamcandae 6-15 part, Herba Cirsii 5-25 part.
3. the Chinese medicine composition that is used for the treatment of livestock and birds respiratory disease according to claim 2, it is characterized in that described active component is made by Herba Bidentis Bipinnatae 15-25 part, Herba Calthae Membranaceae 15-20 part, Herba Commelinae 12-18 part, Herba Taraxaci 10-15 part, Folium Mori 12-18 part, Radix Isatidis 7-14 part, Rhizoma Belamcandae 8-13 part, Herba Cirsii 10-20 part.
4. the Chinese medicine composition that is used for the treatment of livestock and birds respiratory disease according to claim 3, it is characterized in that described active component is made by 15 parts of 25 parts of Herba Bidentis Bipinnatae, 18 parts of Herba Calthae Membranaceaes, 15 parts of Herba Commelinaes, 12 parts of Herba Taraxacis, 15 parts on Folium Mori, 10 parts of Radix Isatidiss, 10 parts of Rhizoma Belamcandae, Herba Cirsii.
5. each described preparation method that is used for the treatment of the Chinese medicine composition of livestock and birds respiratory disease of claim 1-4, it comprises the steps:
(1) takes by weighing by weight ratio each medicine material;
(2) will claim each medicine material maybe will claim after pulverizing, sieving each medicine material through water or alcohol extraction, concentrated after, add again adjuvant or complementary composition that pharmacy can be used, be prepared from.
6. the preparation method that is used for the treatment of the Chinese medicine composition of livestock and birds respiratory disease according to claim 5 is characterized in that, the dosage form that makes is: powder, pre-mixing agent, powder, granule, oral liquid or injection.
7. each described Chinese medicine composition application in preparation treatment livestock and birds respiratory disease medicine that is used for the treatment of livestock and birds respiratory disease of claim 1-4.
8. each described Chinese medicine composition application in preparation promotion liver cell regeneration medicine that is used for the treatment of livestock and birds respiratory disease of claim 1-4.
9. contain each described feedstuff that is used for the treatment of the Chinese medicine composition of livestock and birds respiratory disease of claim 1-4.
CN2013100373905A 2013-01-31 2013-01-31 Traditional Chinese medicine composition for treating respiratory disease of livestock and poultry and feed of traditional Chinese medicine composition Withdrawn CN103070993A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105028940A (en) * 2015-09-10 2015-11-11 中山市绿涛电子科技有限公司 Duck fodder and preparation method thereof
CN110269928A (en) * 2019-08-09 2019-09-24 山东畜牧兽医职业学院 A kind of drug mixture and preparation method thereof preventing and treating ox infection of the upper respiratory tract disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101972364A (en) * 2010-08-25 2011-02-16 天津生机集团股份有限公司 Medicinal composition for treating avian infectious bronchitis and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101972364A (en) * 2010-08-25 2011-02-16 天津生机集团股份有限公司 Medicinal composition for treating avian infectious bronchitis and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105028940A (en) * 2015-09-10 2015-11-11 中山市绿涛电子科技有限公司 Duck fodder and preparation method thereof
CN110269928A (en) * 2019-08-09 2019-09-24 山东畜牧兽医职业学院 A kind of drug mixture and preparation method thereof preventing and treating ox infection of the upper respiratory tract disease

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