CN105395644A - Traditional Chinese medicinal composition for preventing and treating coccidiosis in chicken as well as preparation method and application of traditional Chinese medicinal composition - Google Patents
Traditional Chinese medicinal composition for preventing and treating coccidiosis in chicken as well as preparation method and application of traditional Chinese medicinal composition Download PDFInfo
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- CN105395644A CN105395644A CN201510870606.5A CN201510870606A CN105395644A CN 105395644 A CN105395644 A CN 105395644A CN 201510870606 A CN201510870606 A CN 201510870606A CN 105395644 A CN105395644 A CN 105395644A
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Abstract
The invention discloses a traditional Chinese medicinal composition for preventing and treating coccidiosis in chicken. The traditional Chinese medicinal composition is prepared from the following components in parts by weight: 5 parts of brucea amarissima, 5 parts of root of Chinese pulsatilla, 5 parts of artemisia apiacea, 3 parts of sanguisorba officinalis, 3 parts of bighead atractylodes rhizome, 3 parts of hairyvein agrimony, 2 parts of liquorice root, 2 parts of radix aucklandiae and 2 parts of radix euphorbiae lantu. The invention also provides a preparation method and application of the traditional Chinese medicinal composition. The traditional Chinese medicinal composition for preventing and treating coccidiosis in chicken as well as the preparation method and the application of the traditional Chinese medicinal composition have the following beneficial effects: (1) the traditional Chinese medicinal composition is capable of effectively preventing the occurrence of the coccidiosis in chicken; (2) the traditional Chinese medicinal composition, which is applied together with drinking water, is simple to operate and is low in cost; (3) the traditional Chinese medicinal composition, as a Chinese herbal medicine preparation, is capable of avoiding such problems as drug resistance and the like, and is capable of greatly reducing failure rate in prevention and treatment; and (4) the traditional Chinese medicinal composition, as a pure traditional Chinese medicinal compound preparation, is low in residue in the chicken and is good in bio-safety.
Description
Technical field
The present invention relates to poultry technical field of traditional Chinese medicine, be specifically related to a kind of for Chinese medicine composition preventing and treating chicken coccidiosis and its preparation method and application.
Background technology
Chicken coccidiosis (Chickencoccidiosis) parasitizes protozoacide caused in Intestinum Gallus domesticus epithelial cell by Eimeria (Eimeria) one or more coccidiosiss; its sickness rate reaches 80% ~ 100%; case fatality rate reaches 20% ~ 30%; time serious, case fatality rate is up to 80%; this disease is very harmful to poultry husbandry; particularly in today of development scale, intensive aviculture, coccidiosis has become the global disease of obstruction set reduction poultry production development.Annual about 2,000,000,000 pounds of the loss that the whole world causes because of coccidiosis.In poultry is produced, all coccidiostat must be added in nearly all chicken feed, China drops into consumption cost average out to every chicken 0.2 yuan ~ 0.3 yuan of prevention primary disease every year, and the expenses for medicine every year for preventing and treating chicken coccidiosis reaches several hundred million yuans, accounts for nearly 1/3 of the whole expenses for prevention and control of fowl disease.For a long time, the anti-system of chemicals is mainly relied on to chicken coccidiosis, due to the improper use and misuse etc. of anticoccidial drug, add the effect of long-term natural selection, make the drug-resistant worm plant of coccidiosis increasing, cause the prevention effect of many anticoccidial drugs significantly to reduce, even completely invalid, the operating period of anticoccidial drug is shortened greatly; Meanwhile, high dose continues to use chemicals control coccidiosis, also can cause drug residue, harm humans.In addition, in control chicken coccidiosis process, though there is live vaccine apply, studies complete not to the utmost because anti-strong, the DNA vaccination of virulence easily occurs live vaccine, therefore not yet promote the use of.Because Chinese herbal medicine mostly is natural plant, use Chinese herb prevention chicken coccidiosis, both can reach the object of control coccidiosis, also can alleviate and affect broiler outlet problem because of residue of veterinary drug.Thus, the preparation of exploitation safety, high-efficiency prevention and control chicken coccidiosis has good market prospect.
Summary of the invention
Object of the present invention is exactly for above-mentioned defect of the prior art, provide a kind of to control chicken coccidiosis effective, low-residual, biological safety good for Chinese medicine composition preventing and treating chicken coccidiosis and its preparation method and application.
To achieve these goals, technical scheme provided by the invention is: a kind of Chinese medicine composition for preventing and treating chicken coccidiosis, prepared by the following component according to parts by weight: Fructus Bruceae 5 parts, the Radix Pulsatillae 5 parts, Herba Artemisiae Annuae 5 parts, Radix Sanguisorbae 3 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Herba Agrimoniae 3 parts, 2 parts, Radix Glycyrrhizae, the Radix Aucklandiae 2 parts, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2 parts.
Further, above-mentioned a kind of Chinese medicine composition for preventing and treating chicken coccidiosis, also comprises pharmaceutically acceptable antiseptic.
Further, above-mentioned a kind of Chinese medicine composition for preventing and treating chicken coccidiosis, described antiseptic is 3 parts of potassium sorbate according to parts by weight and 3 parts of sodium diacetate.
Second object of the present invention there is provided the preparation method of above-mentioned a kind of Chinese medicine composition for preventing and treating chicken coccidiosis, comprises the following steps:
1) sort: remove the impurity in each Chinese medicinal components;
2) pulverize: each component is weighed according to proportioning and after mixing, is ground into 200 object fine powders;
3) soak decoction to extract: soak under the clear water room temperature of the medicated powder 5 times of medicated powder weight crushed 3 hours, then decoct after water boil and extract for 2 hours;
4) secondary soaks to decoct and extracts: soaked 1 hour with under the clear water room temperature of 5 times of former medicated powder weight by isolated medicine residue after first time soak extraction again, then after water boil, decocts extraction in 2 hours;
5) medicinal liquid is merged: merge after the decoction liquor of twice being separated with medicine residue;
6) concentrated: will to decoct and to extract and the concentration of liquid medicine merged becomes the concentrated solution of 1 times of former medicated powder weight;
7) removal impurity is filtered;
8) antiseptic is added according to weight proportion;
9) subpackage.
3rd object of the present invention there is provided the application of above-mentioned a kind of Chinese medicine composition for preventing and treating chicken coccidiosis in the medicine for the preparation of control chicken coccidiosis.
Further, above-mentioned application, is fed in after 1:100 ratio drinking-water by described Chinese medicine composition, 2 times on the one, is used in conjunction 3-5 day.
Provided by the invention a kind of for Chinese medicine composition preventing and treating chicken coccidiosis and its preparation method and application, there is following beneficial effect:
(1) can the generation of effectively preventing chicken coccidiosis;
(2) can adopt drinking water administration, simple to operate, cost is low;
(3) because the present invention is Chinese herbal and crude drugs preparations, avoid the generation of the problems such as drug resistance, greatly reduce the probability that control is failed;
(4) the present invention is pure Chinese medicine compound, and low-residual in chicken body, biological safety is good.
Detailed description of the invention
embodiment 1:
For preventing and treating a Chinese medicine composition for chicken coccidiosis, prepared by following component: Fructus Bruceae 5kg, Radix Pulsatillae 5kg, Herba Artemisiae Annuae 5kg, Radix Sanguisorbae 3kg, Rhizoma Atractylodis Macrocephalae 3kg, Herba Agrimoniae 3kg, Radix Glycyrrhizae 2kg, Radix Aucklandiae 2kg, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2kg.
Its preparation method comprises the following steps:
1) sort: remove the impurity in each Chinese medicinal components;
2) pulverize: each component is weighed according to proportioning and after mixing, is ground into 200 object fine powders;
3) soak decoction to extract: soak under the clear water room temperature of the medicated powder 5 times of medicated powder weight crushed 3 hours, then decoct after water boil and extract for 2 hours;
4) secondary soaks to decoct and extracts: soaked 1 hour with under the clear water room temperature of 5 times of former medicated powder weight by isolated medicine residue after first time soak extraction again, then after water boil, decocts extraction in 2 hours;
5) medicinal liquid is merged: merge after the decoction liquor of twice being separated with medicine residue;
6) concentrated: will to decoct and to extract and the concentration of liquid medicine merged becomes the concentrated solution of 1 times of former medicated powder weight;
7) removal impurity is filtered;
8) subpackage.
embodiment 2:
For preventing and treating a Chinese medicine composition for chicken coccidiosis, prepared by following component: Fructus Bruceae 5kg, Radix Pulsatillae 5kg, Herba Artemisiae Annuae 5kg, Radix Sanguisorbae 3kg, Rhizoma Atractylodis Macrocephalae 3kg, Herba Agrimoniae 3kg, Radix Glycyrrhizae 2kg, Radix Aucklandiae 2kg, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2kg, as potassium sorbate 3kg and the sodium diacetate 3kg of antiseptic.
Its preparation method comprises the following steps:
1) sort: remove the impurity in each Chinese medicinal components;
2) pulverize: each component is weighed according to proportioning and after mixing, is ground into 200 object fine powders;
3) soak decoction to extract: soak under the clear water room temperature of the medicated powder 5 times of medicated powder weight crushed 3 hours, then decoct after water boil and extract for 2 hours;
4) secondary soaks to decoct and extracts: soaked 1 hour with under the clear water room temperature of 5 times of former medicated powder weight by isolated medicine residue after first time soak extraction again, then after water boil, decocts extraction in 2 hours;
5) medicinal liquid is merged: merge after the decoction liquor of twice being separated with medicine residue;
6) concentrated: will to decoct and to extract and the concentration of liquid medicine merged becomes the concentrated solution of 1 times of former medicated powder weight;
7) removal impurity is filtered;
8) antiseptic is added according to weight proportion;
9) subpackage.
embodiment 3:
application Example:
Get crude drug 90.0kg altogether, the weight of each crude drug is respectively: Fructus Bruceae 15.0kg, Radix Pulsatillae 15.0kg, Herba Artemisiae Annuae 15.0kg, Radix Sanguisorbae 9.0kg, Rhizoma Atractylodis Macrocephalae 9.0kg, Herba Agrimoniae 9.0kg, Radix Glycyrrhizae 6.0kg, Radix Aucklandiae 6.0kg, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 6.0kg.Through sorting, be ground into 200 object fine powders, soak under the clear water room temperature of medicated powder 5 times of drug weight of crushing and 450.0kg 3 hours, decoct and be separated medicinal liquid and medicine residue after 2 hours, leave and take medicinal liquid for subsequent use, soak 1 hour under more isolated medicine residue being added the clear water room temperature of 5 times of former medicated powder weight, decoct 2 hours, isolate medicinal liquid, the concentrated solution of 1 times of former medicated powder weight is condensed into after being mixed by the medicinal liquid of extracted twice, filter, add 9.0g potassium sorbate and 9.0g sodium diacetate antiseptic, subpackage obtains finished product, is below embody rule situation:
(1) laying hen 12900 of solid chicken house 43 age in days in west, Gansu, has 60% to occur down in spirits, and feather is inverse vertical, eye closing necking down, crop distension, and poor appetite is even absolutely useless, and happiness flocks together.Chicken group main manifestations row loose stool, be with blood or feces to be brownish red in feces, perianal feather is by blood contamination.Indivedual chicken occurs that Corium Gallus domesticus skin, cockscomb, cloaca, oral mucosa and eye conjunctiva are pale, even occurs that ataxia, wing are sagging, the symptom such as neural paralysis or spasm.Cut open the inspection visible caecum of sick chicken flat remarkable enlargement, be full of blood or blood clotting thing or bean dregs sample sphacelus in enteric cavity, serosal surface becomes brownish red, and pachymucosa is rotten to the corn, caecum sclerosis, becomes fragile, and it is downright bad that indivedual natural death chicken rectum has greyish white colour circle to fill.According to epidemiology, clinical symptoms, cut open inspection change and coccidian oocyst microscopic examination determine that chicken group there occurs coccidium infection, be diagnosed as chicken coccidiosis.The Chinese herbal medicine extract preparation that application said method obtains is treated in the dilution of 1:50 ratio clear water, one day 2 times, is used in conjunction 5 days.Medication after 3 days symptom obviously alleviate, after 5 days whole chicken group spirit, search for food, drink water and all recover normal, the state of an illness obtains effective control, and cure rate is 88.4%, and effective percentage is 100%.
(2) the flat poultry mass-sending in Tianshui city chicken house 3600 ground live chickens coccidiosis, the Chinese herbal medicine extract preparation that application said method obtains is drunk to chicken according to after 1:50 thin up, every day 2 times, be used in conjunction 5 days, after medication, the 2nd day 73.4% sick chicken symptom obviously alleviates, within 4th day, the state of an illness is controlled, and cure rate is 89.4%, and effective percentage is 100%.
(3) 4500, Longnan City, Gansu Province broiler breeding field chicken generation chicken coccidiosis, the Chinese herbal medicine extract preparation of the control coccidiosis that application said method obtains is drunk to chicken according to after 1:50 thin up, every day 2 times, be used in conjunction 2 days, the searching for food of chicken group, to drink water and mental status shape obtains obvious improvement, when the 5th day, the respiratory symptom of chicken group disappears, and the state of an illness is under control, cure rate is 89.2%, and effective percentage is 100%.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. for preventing and treating a Chinese medicine composition for chicken coccidiosis, it is characterized in that, is prepared by the following component according to parts by weight: Fructus Bruceae 5 parts, the Radix Pulsatillae 5 parts, Herba Artemisiae Annuae 5 parts, Radix Sanguisorbae 3 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Herba Agrimoniae 3 parts, 2 parts, Radix Glycyrrhizae, the Radix Aucklandiae 2 parts, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 2 parts.
2. a kind of Chinese medicine composition for preventing and treating chicken coccidiosis according to claim 1, is characterized in that, also comprise pharmaceutically acceptable antiseptic.
3. a kind of Chinese medicine composition for preventing and treating chicken coccidiosis according to claim 2, is characterized in that, described antiseptic is 3 parts of potassium sorbate according to parts by weight and 3 parts of sodium diacetate.
4., according to the preparation method of the arbitrary described a kind of Chinese medicine composition for preventing and treating chicken coccidiosis of claim 1-3, it is characterized in that, comprise the following steps:
1) sort: remove the impurity in each Chinese medicinal components;
2) pulverize: each component is weighed according to proportioning and after mixing, is ground into 200 object fine powders;
3) soak decoction to extract: soak under the clear water room temperature of the medicated powder 5 times of medicated powder weight crushed 3 hours, then decoct after water boil and extract for 2 hours;
4) secondary soaks to decoct and extracts: soaked 1 hour with under the clear water room temperature of 5 times of former medicated powder weight by isolated medicine residue after first time soak extraction again, then after water boil, decocts extraction in 2 hours;
5) medicinal liquid is merged: merge after the decoction liquor of twice being separated with medicine residue;
6) concentrated: will to decoct and to extract and the concentration of liquid medicine merged becomes the concentrated solution of 1 times of former medicated powder weight;
7) removal impurity is filtered;
8) antiseptic is added according to weight proportion;
9) subpackage.
5. according to the application of the arbitrary described a kind of Chinese medicine composition for preventing and treating chicken coccidiosis of claim 1-3 in the medicine for the preparation of control chicken coccidiosis.
6. application according to claim 5, is characterized in that, is to be fed in after 1:100 ratio drinking-water by described Chinese medicine composition, 2 times on the one, is used in conjunction 3-5 day.
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| CN201510870606.5A CN105395644A (en) | 2015-12-02 | 2015-12-02 | Traditional Chinese medicinal composition for preventing and treating coccidiosis in chicken as well as preparation method and application of traditional Chinese medicinal composition |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107308235A (en) * | 2017-06-27 | 2017-11-03 | 齐全农牧集团股份有限公司 | A kind of Chinese medicine composition and preparation method for preventing and treating chicken coccidiasis |
| CN110141590A (en) * | 2019-06-28 | 2019-08-20 | 江苏省家禽科学研究所 | Kostelezkya virginica Chinese medicine complex composition and its application for preventing and treating chicken coccidiasis |
| CN111011628A (en) * | 2019-12-19 | 2020-04-17 | 何先清 | Plant extract and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1145791A (en) * | 1995-09-20 | 1997-03-26 | 山东省鲁西兽药厂 | Coccidiosis-resisting Chinese herbal veterinary medicine and its prepn |
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2015
- 2015-12-02 CN CN201510870606.5A patent/CN105395644A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1145791A (en) * | 1995-09-20 | 1997-03-26 | 山东省鲁西兽药厂 | Coccidiosis-resisting Chinese herbal veterinary medicine and its prepn |
Non-Patent Citations (1)
| Title |
|---|
| 闫若潜等主编: "《动物疫病防控工作指南》", 30 June 2014, 中国农业出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107308235A (en) * | 2017-06-27 | 2017-11-03 | 齐全农牧集团股份有限公司 | A kind of Chinese medicine composition and preparation method for preventing and treating chicken coccidiasis |
| CN110141590A (en) * | 2019-06-28 | 2019-08-20 | 江苏省家禽科学研究所 | Kostelezkya virginica Chinese medicine complex composition and its application for preventing and treating chicken coccidiasis |
| CN110141590B (en) * | 2019-06-28 | 2021-09-07 | 江苏省家禽科学研究所 | Kosteletzkya virginica traditional Chinese medicine composite composition for preventing and treating chicken coccidiosis and application thereof |
| CN111011628A (en) * | 2019-12-19 | 2020-04-17 | 何先清 | Plant extract and preparation method and application thereof |
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Application publication date: 20160316 |
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