CN103230512B - Traditional Chinese medicine composition for preventing and treating chronic respiratory diseases in chicken as well as preparation method and application thereof - Google Patents
Traditional Chinese medicine composition for preventing and treating chronic respiratory diseases in chicken as well as preparation method and application thereof Download PDFInfo
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- CN103230512B CN103230512B CN201310154850.2A CN201310154850A CN103230512B CN 103230512 B CN103230512 B CN 103230512B CN 201310154850 A CN201310154850 A CN 201310154850A CN 103230512 B CN103230512 B CN 103230512B
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Abstract
The invention discloses a traditional Chinese medicine composition for preventing and treating chronic respiratory diseases in chicken. The composition comprises the following ingredients in parts by weight: 6 parts of ephedra, 6 parts of almond, 6 parts of gypsum, 6 parts of fructus perillae, 4 parts of white mulberry root-bark, 4 parts of pinellia tuber, 4 parts of baical skullcap root, 4 parts of tendrilleaf fritillary bulb and 1 part of liquorice. The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition has good effects on preventing and treating chronic respiratory diseases in chicken, has multitarget property toward effects on mycoplasma and has low residues and good biosafety.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly, relate to a kind of Chinese medicine composition of preventing and treating chronic respiratory disease.
Background technology
Chronic respiratory disease of fowl (CRD) (be called for short CRD) claims again chicken virus mycoplasma sick, is the chronic infectious disease of a kind of height contact of being caused by Mycoplasma gallisepticum (Mycoplasma gallisepticum, MG).Sick chicken and the chicken that carries disease germs are the sources of infection of primary disease, mainly through feedstuff, drinking-water and the egg of the spittle, pollution, propagate, and the chicken at various ages all can infect.This disease is clinical is chronic process, and the course of disease is long, and frequent and other cause of disease mixed infections again, cause respiratory symptom aggravation, and mortality rate increases; And because infected chicken growth promoter is obstructed, the discarded rate of the defect ware of trunk improves, laying rate reduces, and to poultry husbandry, causes serious threat.Utilizing antibacterial drug therapy primary disease is the major measure of taking both at home and abroad at present, but treats unsuccessfully because the problems such as antibiotic resistance often make it; Because drug residue can produce toxic and side effects, make people give more and more large hope to Chinese herb prevention.Thereby the preparation of exploitation safety, high-efficiency prevention and control mycoplasma gallinarum has good market prospect.
Summary of the invention
The technical problem to be solved in the present invention is to overcome existing defect, and a kind of Chinese medicine composition and preparation and application that prevents and treats chronic respiratory disease is provided.That Chinese medicine composition of the present invention has advantages of is effective to control chronic respiratory disease, to mycoplasma effect to have many targets, low-residual, biological safety good.
In order to solve the problems of the technologies described above, the invention provides following technical scheme:
Prevent and treat a Chinese medicine composition for chronic respiratory disease, comprise the component of following weight portion:
6 parts, Herba Ephedrae, 6 parts, Semen Armeniacae Amarum, 6 parts, Gypsum Fibrosum, 6 parts of Fructus Perillaes, 4 parts of Cortex Mori, 4 parts of the Rhizoma Pinelliaes, 4 parts of Radix Scutellariaes, 4 parts of Bulbus Fritillariae Cirrhosaes, 1 part, Radix Glycyrrhizae.
Particularly, also comprise pharmaceutically acceptable antiseptic.
Preferably, described antiseptic is potassium sorbate and sodium diacetate.
The preparation method of the Chinese medicine composition of control chronic respiratory disease of the present invention, comprises the following steps:
(1) sorting: remove the impurity in each component;
(2) pulverize: each component is weighed and mix after be ground into 200 object fine powders;
(3) soak and decoct extraction: under the clear water room temperature by the medicated powder crushing by 5 times of drug weight, soak 3 hours, then after water boil, decoct extraction in 2 hours;
(4) secondary soaks to decoct and extracts: isolated medicine residue after soaking extraction is for the first time soaked 1 hour under the clear water room temperature by 5 times of former medicated powder weight again, then after water boil, decoct extraction in 2 hours;
(5) merge medicinal liquid: after the decoction liquor of twice is separated with medicine residue, merge;
(6) concentrated: the concentrated solution that the medicinal liquid that decocts extraction and merge is condensed into 1 times of former medicated powder weight;
(7) filter and remove impurity;
(8) add antiseptic;
(9) subpackage.
The application of the Chinese medicine composition of control chronic respiratory disease of the present invention in preparation control chronic respiratory disease medicine.
the present invention has following beneficial effect:
(1) generation that can effectively preventing chronic respiratory disease;
(2) can adopt drinking-water or spice administration, simple to operate, cost is low;
(3) because the present invention is Chinese herbal and crude drugs preparations, avoided the generation of the problems such as drug resistance, greatly reduced and prevented and treated failed probability;
(4) the present invention is pure Chinese medicine compound, low-residual in chicken body, and biological safety is good.
using method of the present invention:
After being diluted with clear water in 1:100 ratio, drinks product of the present invention to chicken, and 2 times on the one, be used in conjunction 3-5 day, can effectively control mycoplasma gallinarum and infect.
The specific embodiment
product embodiments:
embodiment 1
Prevent and treat the Chinese medicine composition of chronic respiratory disease, comprise the component of following weight portion:
6 parts, Herba Ephedrae, 6 parts, Semen Armeniacae Amarum, 6 parts, Gypsum Fibrosum, 6 parts of Fructus Perillaes, 4 parts of Cortex Mori, 4 parts of the Rhizoma Pinelliaes, 4 parts of Radix Scutellariaes, 4 parts of Bulbus Fritillariae Cirrhosaes, 1 part, Radix Glycyrrhizae.
embodiment 2
Prevent and treat the Chinese medicine composition of chronic respiratory disease, comprise the component of following weight portion:
6 parts, Herba Ephedrae, 6 parts, Semen Armeniacae Amarum, 6 parts, Gypsum Fibrosum, 6 parts of Fructus Perillaes, 4 parts of Cortex Mori, 4 parts of the Rhizoma Pinelliaes, 4 parts of Radix Scutellariaes, 4 parts of Bulbus Fritillariae Cirrhosaes, 1 part, Radix Glycyrrhizae, and the potassium sorbate and the sodium diacetate that as antiseptic, use.
preparation Example:
embodiment 3
The preparation method of the Chinese medicine composition of control chronic respiratory disease, comprises the following steps:
(1) sorting: remove the impurity in each component;
(2) pulverize: each component is weighed and mix after be ground into 200 object fine powders;
(3) soak and decoct extraction: under the clear water room temperature by the medicated powder crushing by 5 times of drug weight, soak 3 hours, then after water boil, decoct extraction in 2 hours;
(4) secondary soaks to decoct and extracts: isolated medicine residue after soaking extraction is for the first time soaked 1 hour under the clear water room temperature by 5 times of former medicated powder weight again, then after water boil, decoct extraction in 2 hours;
(5) merge medicinal liquid: after the decoction liquor of twice is separated with medicine residue, merge;
(6) concentrated: the concentrated solution that the medicinal liquid that decocts extraction and merge is condensed into 1 times of former medicated powder weight;
(7) filter and remove impurity;
(8) add antiseptic;
(9) subpackage.
application Example:
Get crude drug 31.0kg altogether, the weight of each crude drug is respectively: Herba Ephedrae 6.0 kg, Semen Armeniacae Amarum 6.0 kg, Gypsum Fibrosum 6.0 kg, Fructus Perillae 6.0 kg, Cortex Mori 4.0 kg, the Rhizoma Pinelliae 4.0 kg, Radix Scutellariae 4.0 kg, Bulbus Fritillariae Cirrhosae 4.0 kg, Radix Glycyrrhizae 1.0 kg.Through sorting, be ground into 200 object fine powders, under the clear water room temperature that is 155.0kg by 5 times of drug weight by the medicated powder crushing, soak 3 hours, decoct separated medicinal liquid and medicine residue after 2 hours, leave and take medicinal liquid standby, again isolated medicine residue is added under the clear water room temperature of 5 times of former medicated powder weight and soak 1 hour, decoct 2 hours, isolate medicinal liquid, after being mixed, the medicinal liquid of extracted twice is condensed into the concentrated solution of 1 times of former medicated powder weight, filter, add 3.1 g potassium sorbate and 3.1 g sodium diacetate antiseptic, subpackage makes finished product, is below concrete applicable cases:
(1) the blue or green foot of feeding of broiler field, Yongdeng County, Gansu Province county 44 ages in days fiber crops plumage broiler is 2500, have 40% go out to lose face flushing, swelling, shed tears, trachea has rale, cough, sneeze, mouth breathing, spirit is depressed, loss of appetite.Cut open that inspection sick chicken visible annulus trachealis is hemorrhage, the typical mycoplasma gallinarum infection lesion such as airsacculitis (breast, saccus abdominalis serious muddy, thicken), fiber disposition perihepatitis, cellulose effusive pericarditis.According to epidemiology, clinical symptoms, cut open that inspection changes and chicken virus mycoplasma plate agglutination test serological reaction determines that chicken mass-sending given birth to mycoplasma infection, be diagnosed as chronic respiratory disease.The Chinese herbal medicine extract preparation that application said method makes is treated with clear water dilution in 1:100 ratio, one day 2 times, is used in conjunction 5 days.Medication after 2 days symptom obviously alleviate, whole chicken group's spirit after 5 days, search for food, drink water and all recover normal, the state of an illness has obtained effective control, cure rate is 90.2%, effective percentage is 100%.
(2) 2400 of Tianshui city laying hen fields laying hen generation chronic respiratory disease infects, the Chinese herbal medicine extract preparation that makes of application said method is drunk to chicken after according to 1:100 thin up, every day 2 times, be used in conjunction 5 days, after medication, the 2nd day 70% sick chicken symptom obviously alleviates, within the 4th day, the state of an illness is controlled, and cure rate is 92.5%, and effective percentage is 100%.
(3) when 1500 of Xigu District, Lanzhou City, Gansu Province broiler breeding fields chicken generation chronic respiratory disease infects, the Chinese herbal medicine extract preparation of the control chronic respiratory disease that makes of application said method is drunk to chicken after according to 1:100 thin up, every day 2 times, be used in conjunction 2 days, the searching for food of chicken group, drinking-water and mental status shape have obtained obvious improvement, and in the time of the 5th day, chicken group's respiratory symptom disappears, and the state of an illness is under control, cure rate is 94.4%, and effective percentage is 100%.
Finally it should be noted that: the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (6)
1. a Chinese medicine composition of preventing and treating chronic respiratory disease, is characterized in that, consists of: 6 parts, Herba Ephedrae, 6 parts, Semen Armeniacae Amarum, 6 parts, Gypsum Fibrosum, 6 parts of Fructus Perillaes, 4 parts of Cortex Mori, 4 parts of the Rhizoma Pinelliaes, 4 parts of Radix Scutellariaes, 4 parts of Bulbus Fritillariae Cirrhosaes, 1 part, Radix Glycyrrhizae each component of following weight portion.
2. a Chinese medicine composition of preventing and treating chronic respiratory disease, it is characterized in that, by each component of following weight portion, formed: 6 parts, Herba Ephedrae, 6 parts, Semen Armeniacae Amarum, 6 parts, Gypsum Fibrosum, 6 parts of Fructus Perillaes, 4 parts of Cortex Mori, 4 parts of the Rhizoma Pinelliaes, 4 parts of Radix Scutellariaes, 4 parts of Bulbus Fritillariae Cirrhosaes, 1 part, Radix Glycyrrhizae, and pharmaceutically acceptable antiseptic.
3. according to the Chinese medicine composition of the control chronic respiratory disease described in claim 2, it is characterized in that, described antiseptic is potassium sorbate and sodium diacetate.
4. the preparation method of the Chinese medicine composition of the control chronic respiratory disease described in claim 2 or 3, comprises the following steps:
(1) sorting: remove the impurity in each component;
(2) pulverize: each component is weighed and mix after be ground into 200 object fine powders;
(3) soak and decoct extraction: under the clear water room temperature by the medicated powder crushing by 5 times of drug weight, soak 3 hours, then after water boil, decoct extraction in 2 hours;
(4) secondary soaks to decoct and extracts: isolated medicine residue after soaking extraction is for the first time soaked 1 hour under the clear water room temperature by 5 times of former medicated powder weight again, then after water boil, decoct extraction in 2 hours;
(5) merge medicinal liquid: after the decoction liquor of twice is separated with medicine residue, merge;
(6) concentrated: the concentrated solution that the medicinal liquid that decocts extraction and merge is condensed into 1 times of former medicated powder weight;
(7) filter and remove impurity;
(8) add antiseptic;
(9) subpackage.
5. the application of the Chinese medicine composition of the control chronic respiratory disease described in claim 1 in preparation control chronic respiratory disease medicine.
6. the application of the Chinese medicine composition of the control chronic respiratory disease described in claim 2 or 3 in preparation control chronic respiratory disease medicine.
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