CN104825544B - A kind of Chinese medicine composition and its preparation method and application for preventing and treating infectious coryza of chicken - Google Patents
A kind of Chinese medicine composition and its preparation method and application for preventing and treating infectious coryza of chicken Download PDFInfo
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Abstract
The invention discloses a kind of for preventing and treating the Chinese medicine composition of infectious coryza of chicken, is to be prepared by following bulk pharmaceutical chemicals in parts by weight: 20 parts of the frying achene of Siberian cocklebur, 20 parts of the flower bud of lily magnolia, 11 parts of the root of Dahurain angelica, 5 parts of asarum, 11 parts of chrysanthemum, 6 parts of peppermint, 11 parts of honeysuckle, 11 parts of Radix Astragali, 5 parts of Radix Glycyrrhizae；And provide preparation method and application.The invention has the benefit that provided by the present invention for prevent and treat infectious coryza of chicken Chinese medicine composition, have the following advantages that, 1) can effectively preventing infectious coryza of chicken generation；2) drinking-water or spice administration can be used, it is easy to operate, it is at low cost；3) generation for the problems such as being Chinese herbal and crude drugs preparations, avoided drug resistance due to the present invention greatly reduces the probability of prevention and treatment failure；4) pure Chinese medicine compound, the low-residual in chicken body, biological safety are good.
Description
Technical field
The present invention relates to livestock and poultry pharmaceutical compositions, and in particular to a kind of for preventing and treating the Chinese traditional medicine composition of infectious coryza of chicken
Object and its preparation method and application.
Background technique
The infective rhinitis (abbreviation IC) of chicken is a breeder acute upper respiratory tract as caused by haemophilus paragallinarum (Hpg)
Infectious disease is one of the most common type condition sexually transmitted disease in poultry production, and the chicken of different days can infect, and occurs mainly in 4
Chicken the group more than monthly age, Growing Chicken and laying hen most easy infection, after infection, can cause laying hen egg yield to decline, Growing Chicken is raw
Long impaired development and mortality increase, meat quality of table poultry decline, the decline of adult chicken egg productivity or stopping, and the duration is long, easily
Recurrence, it is difficult to eradicate, often cause huge economic loss to raiser, seriously threaten the economic development of chicken house.It is controlled using Western medicine
It treats, is the major measure taken both at home and abroad at present, but easily generate bacterial drug resistance often to make its treatment failure；Due to medicament residue
Toxic side effect can be generated, the prevention and treatment of people's centering medicine is made to express more and more big hope.Thus, it develops safe and efficient prevention and treatment chicken and passes
The Chinese herbal compound preparation of metachromia rhinitis has preferable market prospects.
Summary of the invention
The purpose of the present invention is to above-mentioned defects in the prior art, and chicken infection can be effectively prevented by providing one kind
The Chinese medicine composition of property rhinitis.
To achieve the goals above, technical solution provided by the invention are as follows: a kind of for preventing and treating in infectious coryza of chicken
Drug composition is prepared by following bulk pharmaceutical chemicals in parts by weight: 20 parts of the frying achene of Siberian cocklebur, 20 parts of the flower bud of lily magnolia, and the root of Dahurain angelica
11 parts, 5 parts of asarum, 11 parts of chrysanthemum, 6 parts of peppermint, 11 parts of honeysuckle, 11 parts of Radix Astragali, 5 parts of Radix Glycyrrhizae.
Further, above-mentioned a kind of for preventing and treating the Chinese medicine composition of infectious coryza of chicken, it further include having pharmaceutically may be used
The preservative of receiving.
Further, above-mentioned a kind of for preventing and treating the Chinese medicine composition of infectious coryza of chicken, the preservative is appropriate
Potassium sorbate and sodium Diacetate.
A second object of the present invention is to provide above-mentioned a kind of for preventing and treating the Chinese medicine composition of infectious coryza of chicken
Preparation method, comprising the following steps:
1) it sorts: removing the impurity in each bulk pharmaceutical chemicals；
2) it crushes: being ground into 200 targeted fine powders after each bulk pharmaceutical chemicals component is weighed and mixed；
3) it impregnates to decoct and extract: 3 hours will be impregnated under the clear water room temperature of 5 times of drug weights of the medicinal powder crushed, then
It decocts 2 hours and extracts after being boiled with boiling；
4) secondary immersion, which decocts, extracts: the drug residue isolated after first time soak extraction is used 5 times of raw medicine powder weights again
It is impregnated 1 hour under the clear water room temperature of amount, decocts 2 hours and extract after then being boiled with boiling；
5) merge medical fluid: after decoction liquor twice is separated with drug residue, decoction liquor being merged；
6) it is concentrated: combined medical fluid is condensed into the concentrate of 1 times of raw medicine powder weight；
7) filtering removal impurity；
8) preservative is added；
9) Chinese medicine composition can be obtained in packing.
Third object of the present invention is to provide a kind of above-mentioned Chinese medicine compositions for preventing and treating infectious coryza of chicken to exist
Application in the pharmaceutical preparation of preparation prevention and treatment infectious coryza of chicken.
Further, above-mentioned application is drunk after diluting Chinese medicine composition with clear water in the ratio of 1:50 to chicken, and one day
It 2 times, is used in conjunction 3-5 days.
The invention has the benefit that having provided by the present invention for the Chinese medicine composition for preventing and treating infectious coryza of chicken
Following advantages,
1) can effectively preventing infectious coryza of chicken generation；
2) drinking-water or spice administration can be used, it is easy to operate, it is at low cost；
3) generation for the problems such as being Chinese herbal and crude drugs preparations, avoided drug resistance due to the present invention greatly reduces prevention and treatment failure
Probability；
4) pure Chinese medicine compound, the low-residual in chicken body, biological safety are good.
Specific embodiment
Embodiment 1:
It is a kind of for preventing and treating the Chinese medicine composition of infectious coryza of chicken, be to be prepared by following bulk pharmaceutical chemicals: frying is grey
Ears or side handles of a utensil 20kg, flower bud of lily magnolia 20kg, root of Dahurain angelica 11kg, asarum 5kg, chrysanthemum 11kg, peppermint 6kg, honeysuckle 11kg, Radix Astragali 11kg, Radix Glycyrrhizae
5kg。
Preparation method, comprising the following steps:
1) it sorts: removing the impurity in each bulk pharmaceutical chemicals；
2) it crushes: being ground into 200 targeted fine powders after each bulk pharmaceutical chemicals component is weighed and mixed；
3) it impregnates to decoct and extract: 3 hours will be impregnated under the clear water room temperature of 5 times of drug weights of the medicinal powder crushed, then
It decocts 2 hours and extracts after being boiled with boiling；
4) secondary immersion, which decocts, extracts: the drug residue isolated after first time soak extraction is used 5 times of raw medicine powder weights again
It is impregnated 1 hour under the clear water room temperature of amount, decocts 2 hours and extract after then being boiled with boiling；
5) merge medical fluid: after decoction liquor twice is separated with drug residue, decoction liquor being merged；
6) it is concentrated: combined medical fluid is condensed into the concentrate of 1 times of raw medicine powder weight；
7) filtering removal impurity；
8) Chinese medicine composition can be obtained in packing.
Embodiment 2:
It is same as Example 1, institute the difference is that, be also added into the 10g potassium sorbate and 10g used as preservative
Sodium Diacetate, preparation method, comprising the following steps:
1) it sorts: removing the impurity in each bulk pharmaceutical chemicals；
2) it crushes: being ground into 200 targeted fine powders after each bulk pharmaceutical chemicals component is weighed and mixed；
3) it impregnates to decoct and extract: 3 hours will be impregnated under the clear water room temperature of 5 times of drug weights of the medicinal powder crushed, then
It decocts 2 hours and extracts after being boiled with boiling；
4) secondary immersion, which decocts, extracts: the drug residue isolated after first time soak extraction is used 5 times of raw medicine powder weights again
It is impregnated 1 hour under the clear water room temperature of amount, decocts 2 hours and extract after then being boiled with boiling；
5) merge medical fluid: after decoction liquor twice is separated with drug residue, decoction liquor being merged；
6) it is concentrated: combined medical fluid is condensed into the concentrate of 1 times of raw medicine powder weight；
7) filtering removal impurity；
8) preservative is added；
9) Chinese medicine composition can be obtained in packing.
Embodiment 3:
Application Example:
The total 31.0kg of crude drug is taken, the weight of each crude drug is respectively as follows: 6.2 kg of the achene of Siberian cocklebur (stir-fry), 6.2 kg of the flower bud of lily magnolia,
3.41 kg of the root of Dahurain angelica, 1.55 kg of asarum, 3.41 kg of chrysanthemum, 1.86 kg of peppermint, 3.41 kg of honeysuckle, 3.41 kg of Radix Astragali,
1.55 kg of Radix Glycyrrhizae.It is sorted, be ground into 200 targeted fine powders, the medicinal powder crushed is clear with 5 times of i.e. 155.0kg of drug weight
It is impregnated 3 hours under water room temperature, separation medical fluid and drug residue after decocting 2 hours, leaves and takes that medical fluid is spare, then the drug that will be isolated
Residue, which is added under the clear water room temperature of 5 times of raw medicine powder weight, to be impregnated 1 hour, is decocted 2 hours, medical fluid is isolated, by what is extracted twice
The concentrate of 1 times of raw medicine powder weight is condensed into after medical fluid mixing, filtering, adds 3.1 g potassium sorbates and 3.1g sodium Diacetate is anti-
Rotten agent dispenses finished product, and the following are concrete application situations:
(1) laying hen 4300 of 43 week old of Yuzhong, Gansu county broiler feeding field, have 60% appearance spirit depressed, and feather is slightly random,
It curls up motionless, poor appetite even abolish.There are serosity or mucous secretion in the main performance nasal cavity of chicken group and sinus, face
Oedema and conjunctivitis.Eye socket gathers tear bubble, and nose is got rid of in sneezing, and mucus sexual secretion is flowed out in nose, and is formed in nares light
The dry scab of Huang.Conjunctiva inflammation, eyelid swelled, serious chicken eyelid cannot be opened by secretion adhesion, or even blindness.Dissect diseased chicken can
See that acute catarrhal inflammation occurs for sinus and tunica mucosa tracheae under nasal cavity, socket of the eye, sinus is sticky full of water sample or even canescence under nasal cavity and socket of the eye
Property liquid, mucous membrane flush thicken.Lower jaw and facial area subcutaneous tissue thicken, the typical infectious coryza of chicken such as gel-shaped oedema
Lesion.It is detected according to epidemiology, clinical symptoms, dissect variation and infectious coryza of chicken ELISA and determines that pair has occurred in chicken group
Haemophilus gallinarum infection is diagnosed as chicken and infects rhinitis.Using Chinese herbal medicine extract preparation made from the above method in 1:50 ratio
It is treated with clear water dilution, two times a day, is used in conjunction 5 days.Symptom is substantially reduced after medication 3 days, the spirit of entire chicken group after 5 days,
Feeding, drinking-water restore normal, and the state of an illness has obtained effective control, cure rate 87.2%, and effective percentage is 100%.
(2) infectious coryza of chicken occurs for the laying hen of Tianshui city broiler chicken field 1200, using Chinese herbal medicine made from the above method
Extract formulation is drunk after being diluted with water according to 1:50 to chicken, 2 times a day, is used in conjunction 5 days, and the 2nd day 70% diseased chicken symptom is bright after medication
Aobvious to mitigate, the state of an illness is controlled within the 4th day, cure rate 90.4%, and effective percentage is 100%.
(3) infectious coryza of chicken occurs for the chicken of Gansu Province Yongdeng County broiler breeding field 1500, using made from the above method
The Chinese herbal medicine extract preparation of prevention and treatment infectious coryza of chicken is drunk after being diluted with water according to 1:50 to chicken, 2 times a day, is used in conjunction 2 days,
Feeding, drinking-water and the mental status shape of chicken group is obviously improved, and the respiratory symptom of chicken group disappears at the 5th day, and the state of an illness obtains
Control, cure rate 89.9% are arrived, effective percentage is 100%.
Finally, it should be noted that the foregoing is only a preferred embodiment of the present invention, it is not intended to restrict the invention,
Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used
To modify the technical solutions described in the foregoing embodiments or equivalent replacement of some of the technical features.
All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in of the invention
Within protection scope.
Claims (5)
1. a kind of for preventing and treating the Chinese medicine composition of infectious coryza of chicken, which is characterized in that be following by parts by weight
What bulk pharmaceutical chemicals were prepared: 20 parts of the frying achene of Siberian cocklebur, 20 parts of the flower bud of lily magnolia, 11 parts of the root of Dahurain angelica, 5 parts of asarum, 11 parts of chrysanthemum, 6 parts of peppermint, gold
11 parts of honeysuckle flower, 11 parts of Radix Astragali, 5 parts of Radix Glycyrrhizae.
2. according to claim 1 a kind of for preventing and treating the Chinese medicine composition of infectious coryza of chicken, which is characterized in that also wrap
Pharmaceutically acceptable preservative is included.
3. according to claim 2 a kind of for preventing and treating the Chinese medicine composition of infectious coryza of chicken, which is characterized in that described
Preservative is suitable potassium sorbate and sodium Diacetate.
4. it is a method according to any one of claims 1-3 a kind of for preventing and treating the preparation method of the Chinese medicine composition of infectious coryza of chicken,
Characterized by comprising the following steps: 1) sort: removing the impurity in each bulk pharmaceutical chemicals；2) it crushes: each bulk pharmaceutical chemicals component is claimed
It measures and is ground into 200 targeted fine powders after mixing；3) it impregnates to decoct and extract: by the medicinal powder crushed the clear water of 5 times of drug weights
It is impregnated 3 hours under room temperature, decocts 2 hours and extract after then being boiled with boiling；4) secondary immersion, which decocts, extracts: first time is impregnated
The drug residue isolated after extraction is used again to be impregnated 1 hour under the clear water room temperature of 5 times of raw medicine powder weight, is decocted after then being boiled with boiling
It boils 2 hours and extracts；5) merge medical fluid: after decoction liquor twice is separated with drug residue, decoction liquor being merged；6) it is concentrated:
Combined medical fluid is condensed into the concentrate of 1 times of raw medicine powder weight；7) filtering removal impurity；8) preservative is added；9) it dispenses
Chinese medicine composition can be obtained.
5. a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken a method according to any one of claims 1-3 prevents and treats chicken in preparation
Application in the pharmaceutical preparation of infective rhinitis.
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| CN106511916A (en) * | 2015-09-09 | 2017-03-22 | 谭慧敏 | Drug for treating chicken infectious rhinitis |
| CN110946919A (en) * | 2020-01-08 | 2020-04-03 | 河南大德广动物药业有限公司 | Traditional Chinese medicine composition for treating chicken rhinitis and preparation method thereof |
| CN114129619A (en) * | 2021-11-04 | 2022-03-04 | 瑞普（天津）生物药业有限公司 | Traditional Chinese medicine composition for preventing and treating infectious rhinitis of poultry and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101322759A (en) * | 2008-07-07 | 2008-12-17 | 张景峰 | Medicament for treating coryza and preparation thereof |
| CN102846713A (en) * | 2012-09-05 | 2013-01-02 | 河北科技师范学院 | Chinese herbal oral liquid for treating chicken infective rhinitis, and preparation method thereof |
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2015
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101322759A (en) * | 2008-07-07 | 2008-12-17 | 张景峰 | Medicament for treating coryza and preparation thereof |
| CN102846713A (en) * | 2012-09-05 | 2013-01-02 | 河北科技师范学院 | Chinese herbal oral liquid for treating chicken infective rhinitis, and preparation method thereof |
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