CN107684581A - A kind of medicine for treating rhinitis chronic and preparation method thereof - Google Patents
A kind of medicine for treating rhinitis chronic and preparation method thereof Download PDFInfo
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- CN107684581A CN107684581A CN201711095267.3A CN201711095267A CN107684581A CN 107684581 A CN107684581 A CN 107684581A CN 201711095267 A CN201711095267 A CN 201711095267A CN 107684581 A CN107684581 A CN 107684581A
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- almond
- cordate houttuynia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Epidemiology (AREA)
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- Medical Informatics (AREA)
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- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of medicine for treating rhinitis chronic and preparation method thereof, and it is prepared according to a certain weight ratio by cordate houttuynia, Chinese ephedra, almond, and medicine of the present invention has clearing heat and detoxicating, relieving asthma, Li Shui, the function of facilitaing lung, it is quick for treating rhinitis chronic, good effect, do not recur.
Description
Technical field
The present invention relates to a kind of medicine for treating rhinitis chronic and preparation method thereof, belongs to the field of Chinese medicines.
Technical background
Rhinitis chronic is the chronic inflammation of schneiderian membrance and submucosa, its be mainly characterized by inflammation continue more than three months or
Recurrent exerbation, protracted course of disease, intermittent phase can not also recover normal, and without clear and definite pathogenic microorganisms, with different degrees of nose
Plug, secretion increases, and schneiderian membrance swelling or the obstacle such as thickens.The traditional Chinese medical science then thinks that rhinitis chronic is damp and hot with chill, spleen and lung kidney qi deficiency,
Qi depression to blood stasis is relevant.Because western medicine side effect is big, therefore there is pole in people to the Chinese medicine of effectively treatment rhinitis chronic
Big demand, up to now, it has not been found that the relevant report on the present invention.
The content of the invention
The present inventor according to theory of traditional Chinese medical science research and clinical test checking repeatedly, have found finally effectively treat it is chronic
The medicine of rhinitis, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment rhinitis chronic.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is to select cordate houttuynia, Chinese ephedra, almond to be combined preparation, and these drug regimens are caused into each medicine
Thing effect produces synergy, so as to effectively treat rhinitis chronic.Wherein it is because its nature and flavor is pungent from cordate houttuynia, trembles with fear,
Enter meridian of Hand-TAI YIN, there is clearing heat and detoxicating, the function of inducing diuresis to remove edema, control pneumonia, lung abscess, hot dysentery, malaria, oedema, gonorrhoea, leukorrhea,
Carbuncle swells, hemorrhoid, prolapse of the anus, eczema, the favus of the scalp, mange.It is because its nature and flavor is worked hard from Chinese ephedra, temperature, enters lung, bladder warp, there is sweating,
To relieving asthma, Li Shui function, the cold table that cures the wound is real, and fever with chilliness is lossless, headache nasal obstruction, arthralgia, cough and asthma, geomantic omen edema,
Difficult urination, the stupid numbness of ailment said due to cold or exposure, munbness, rubella itch.It is because its is bitter in taste from almond, temperature is poisonous, enters lung, large intestine
Through having expelling phlegm and arresting coughing, relievining asthma, the function of ease constipation, control exogenous cough, asthma is full, larynx numbness, dry constipation of intestines.
Embodiment
The drug dose of instant component is also that inventor show that the dosage of each component is under by largely groping to summarize
Stating all has the effect of preferable in weight range：
15-25 grams of cordate houttuynia, 6-10 grams of Chinese ephedra, 10-15 grams of almond.
Preferable amount is：
20 grams of cordate houttuynia, 8 grams of Chinese ephedra, l2 grams of almond.
The preparation method of medicine of the present invention is as follows
First, stock up
1st, cordate houttuynia：Impurity is removed, removes undesirable root, segment is cleaned, dries；
2nd, Chinese ephedra：Impurity is picked, most woody stems and undesirable root is removed, is eluted with water, segment after micro- profit, dry；
3rd, almond：Net impurity is picked, puts in boiling water and slightly boils, is pulled out when crust microcreping, is soaked in cold water, is sloughed kind of a skin, dry, winnow with a dustpan
Only.
2nd, prepare
1st, the cordate houttuynia after processing, Chinese ephedra, almond are put into decocting container, for the first time plus 6 times of water is measured, after soaking 100 minutes,
High heat decoction is seethed with excitement, then with being cooked by slow fire 20 minutes, filters to obtain first time decoction liquor, first time decoction liquor is poured into container；
2nd, the dregs of a decoction of filtering are added into 4 times of amounts, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；
3rd, it decoction liquor will be mixed evenly twice, and be divided into 2 doses and take.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this hair
The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention：
Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight, is divided to two groups, every group 15, one of which is tested for overdose
Group, another group is normal amount test group.Super quantity group is 20ml/kg, normal amount 10ml/kg, and administering mode is given for administration by gavage
Medicine, twice daily, 7 days are even served, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and medicine is without bad
Toxic side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, general information
Accept rhinitis chronic out-patient totally 32 for medical treatment.
2nd, diagnostic criteria
Classical symptom is has a stuffy nose, runny nose（Mostly translucent mucus nasal mucus）, hyposphresia, headache is dizzy, One's spirits are drooping etc..
3rd, treatment method
From above-mentioned medicament, taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, and 7 days are a course for the treatment of, continuous clothes
With 3 courses for the treatment of.
4th, efficacy assessment standard
It is effective：Rhinitis chronic symptom disappears, and constitution recovers normal, recovery from illness；
Take a turn for the better：Patient's nasal obstruction runny nose, hyposphresia, giddy headache, One's spirits are drooping phenomenon mitigate, and rhinitis chronic symptom is substantially good
Turn, constitution is progressively recovered；
It is invalid：Improvement standard person is not reached.
5th, treatment results（It see the table below）
In above-mentioned treatment, with drug therapy rhinitis chronic patient 32 of the present invention, as a result effective 26, obvious effective rate is
81.25%, take a turn for the better 4, improvement rate 12.5%, invalid 2, total effective rate 93.94%.
Claims (3)
- A kind of 1. medicine for treating rhinitis chronic, it is characterised in that：It is made up of the bulk drug in following weight range：15-25 grams of cordate houttuynia, 6-10 grams of Chinese ephedra, 10-15 grams of almond.
- 2. medicine according to claim 1, wherein the dosage of each bulk drug is：20 grams of cordate houttuynia, 8 grams of Chinese ephedra, l2 grams of almond.
- 3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：（One）Stock（1）Cordate houttuynia：Impurity is removed, removes undesirable root, segment is cleaned, dries；（2）Chinese ephedra：Impurity is picked, most woody stems and undesirable root is removed, is eluted with water, segment after micro- profit, dry；（3）Almond：Net impurity is picked, puts in boiling water and slightly boils, is pulled out when crust microcreping, is soaked in cold water, is sloughed kind of a skin, dry, winnow with a dustpan Only；（Two）Prepare（1）Cordate houttuynia after processing, Chinese ephedra, almond are put into decocting container, add 6 times of amounts of water, after soaking 100 minutes, intense fire Boiling is decocted, then with being cooked by slow fire 20 minutes, filters to obtain first time decoction liquor, first time decoction liquor is poured into container；（2）The dregs of a decoction of filtering are added into 4 times of amounts of water, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；（3）It decoction liquor will be mixed evenly twice, and be divided into 2 doses and take.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711095267.3A CN107684581A (en) | 2017-11-09 | 2017-11-09 | A kind of medicine for treating rhinitis chronic and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711095267.3A CN107684581A (en) | 2017-11-09 | 2017-11-09 | A kind of medicine for treating rhinitis chronic and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107684581A true CN107684581A (en) | 2018-02-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711095267.3A Withdrawn CN107684581A (en) | 2017-11-09 | 2017-11-09 | A kind of medicine for treating rhinitis chronic and preparation method thereof |
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| Country | Link |
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| CN (1) | CN107684581A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927337A (en) * | 2006-08-26 | 2007-03-14 | 闫聿逊 | Preparation process of medicine for treating cough and asthma |
| CN104367689A (en) * | 2013-08-14 | 2015-02-25 | 黄琪玲 | Traditional Chinese medicine composition for treating acute bronchitis |
| CN106668278A (en) * | 2015-11-10 | 2017-05-17 | 沈娟燕 | Formula of traditional Chinese medicine for treating fire-wrapped-by-cold type common cold and nasal obstruction |
-
2017
- 2017-11-09 CN CN201711095267.3A patent/CN107684581A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927337A (en) * | 2006-08-26 | 2007-03-14 | 闫聿逊 | Preparation process of medicine for treating cough and asthma |
| CN104367689A (en) * | 2013-08-14 | 2015-02-25 | 黄琪玲 | Traditional Chinese medicine composition for treating acute bronchitis |
| CN106668278A (en) * | 2015-11-10 | 2017-05-17 | 沈娟燕 | Formula of traditional Chinese medicine for treating fire-wrapped-by-cold type common cold and nasal obstruction |
Non-Patent Citations (7)
| Title |
|---|
| 刘永刚；等: "麻黄汤及拆方抗炎作用的研究", 《中药材》 * |
| 叶宗仁；等: "麻杏石甘汤及其减石膏、甘草对过敏原激发气喘天竺鼠呼吸道阻力与炎细胞的影响", 《安徽中医学院学报》 * |
| 引自中医古籍出版社出版的《图解秘方大全》P.9: "鱼腥草杏仁水泡脚治咳嗽", 《上海医药》 * |
| 张娟: "鱼腥草滴鼻液治疗鼻炎", 《云南中医杂志》 * |
| 游学俊；等: "鱼腥草滴鼻液治疗急慢性鼻炎376例", 《医药导报》 * |
| 苏敬梅；等: "穴位低频电疗加中药治疗小儿气管炎50例", 《河北中医》 * |
| 闫向东: "中医内外治结合治疗痰热型咳嗽54例疗效观察", 《中医临床研究》 * |
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| PB01 | Publication | ||
| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
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Application publication date: 20180213 |