CN104825544A - Chicken infective rhinitis preventing and treating traditional Chinese medicine composition, preparation method and applications thereof - Google Patents
Chicken infective rhinitis preventing and treating traditional Chinese medicine composition, preparation method and applications thereof Download PDFInfo
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Abstract
The present invention discloses a chicken infective rhinitis preventing and treating traditional Chinese medicine composition, a preparation method and applications thereof, wherein the chicken infective rhinitis preventing and treating traditional Chinese medicine composition is prepared from the following bulk drugs by weight: 20 parts of fried fructus xanthii, 20 parts of flos magnoliae, 11 parts of angelica dahurica, 5 parts of asarum sieboldii miq, 11 parts of chrysanthemum, 6 parts of peppermint, 11 parts of honeysuckle, 11 parts of milkvetch root, and 5 parts of licorice root. The chicken infective rhinitis preventing and treating traditional Chinese medicine composition of the present invention has the following advantages that 1) the occurrence of the chicken infective rhinitis can be effectively prevented and treated; 2) the administration with water drinking or material stirring can be adopted, the operation is simple, and the cost is low; 3) the composition is the Chinese herb preparation, such that the generations of drug resistance and other problems are avoided, and the preventing and treating failure probability is substantially reduced; and 4) the composition is the pure tradition Chinese medicine compound, and has characteristics of low residue in chicken and good biosafety.
Description
Technical field
The present invention relates to poultry pharmaceutical composition, be specifically related to a kind of for Chinese medicine composition preventing and treating infectious coryza of chicken and its preparation method and application.
Background technology
Infective rhinitis's (being called for short IC) of chicken is a kind of chicken acute upper respiratory tract infectious disease caused by haemophilus paragallinarum (Hpg), it is modal a kind of conditionality infectious disease during poultry is produced, the chicken of different days all can infect, mainly occur in the chicken group at 4 monthly ages more than, Growing Chicken and the most easy infection of laying hen, after infection, laying hen egg yield can be caused to decline, Growing Chicken growth promoter is obstructed and mortality increases, meat quality of table poultry declines, Adult Chicken egg production declines or stops, and the persistent period is long, easy recurrence, be difficult to eradicate, often cause huge economic loss to raiser, the economic development of serious threat chicken house.Utilizing western medicine, is the major measure taked both at home and abroad at present, but very easily generation bacterial drug resistance often makes its Endodontic failure; Because drug residue can produce toxic and side effects, people are made to express more and more large hope to Chinese herb prevention.Thus, the Chinese herbal compound preparation of exploitation safety, high-efficiency prevention and control infectious coryza of chicken has good market prospect.
Summary of the invention
Object of the present invention is exactly for above-mentioned defect of the prior art, provides a kind of Chinese medicine composition effectively can preventing and treating infectious coryza of chicken.
To achieve these goals, technical scheme provided by the invention is: a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken, prepared by the following crude drug according to parts by weight: parch Fructus Xanthii 20 parts, Flos Magnoliae 20 parts, the Radix Angelicae Dahuricae 11 parts, Herba Asari 5 parts, Flos Chrysanthemi 11 parts, Herba Menthae 6 parts, Flos Lonicerae 11 parts, the Radix Astragali 11 parts, 5 parts, Radix Glycyrrhizae.
Further, above-mentioned a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken, also includes pharmaceutically acceptable antiseptic.
Further, above-mentioned a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken, described antiseptic is appropriate potassium sorbate and sodium diacetate.
Second object of the present invention there is provided the preparation method of above-mentioned a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken, comprises the following steps:
1) sort: remove the impurity in each crude drug;
2) pulverize: each crude drug component is weighed and is ground into 200 object fine powders after mixing;
3) soak decoction to extract: soak under the clear water room temperature of the medicated powder 5 times of drug weight crushed 3 hours, then extract to decoct 2 hours after water boil;
4) secondary soaks to decoct and extracts: soaked 1 hour with under the clear water room temperature of 5 times of former medicated powder weight by isolated medicine residue after first time soak extraction again, then to decoct extraction in 2 hours after water boil;
5) medicinal liquid is merged: after the decoction liquor of twice being separated with medicine residue, decoction liquor merged;
6) concentrated: the concentrated solution concentration of liquid medicine of merging being become 1 times of former medicated powder weight;
7) removal impurity is filtered;
8) antiseptic is added;
9) subpackage can obtain Chinese medicine composition.
3rd object of the present invention there is provided the application of above-mentioned a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken in the pharmaceutical preparation of preparation control infectious coryza of chicken.
Further, above-mentioned application, drinks Chinese medicine composition to chicken in after the ratio clear water dilution of 1:50,2 times on the one, is used in conjunction 3-5 day.
Beneficial effect of the present invention is: the Chinese medicine composition for preventing and treating infectious coryza of chicken provided by the invention, has the following advantages,
1) can the generation of effectively preventing infectious coryza of chicken;
2) can adopt drinking-water or spice administration, simple to operate, cost is low;
3) because the present invention is Chinese herbal and crude drugs preparations, avoid the generation of the problems such as drug resistance, greatly reduce the probability that control is failed;
4) pure Chinese medicine compound, low-residual in chicken body, biological safety is good.
Detailed description of the invention
embodiment 1:
For preventing and treating a Chinese medicine composition for infectious coryza of chicken, prepared by following crude drug: parch Fructus Xanthii 20kg, Flos Magnoliae 20kg, Radix Angelicae Dahuricae 11kg, Herba Asari 5kg, Flos Chrysanthemi 11kg, Herba Menthae 6kg, Flos Lonicerae 11kg, Radix Astragali 11kg, Radix Glycyrrhizae 5kg.
Preparation method, comprises the following steps:
1) sort: remove the impurity in each crude drug;
2) pulverize: each crude drug component is weighed and is ground into 200 object fine powders after mixing;
3) soak decoction to extract: soak under the clear water room temperature of the medicated powder 5 times of drug weight crushed 3 hours, then extract to decoct 2 hours after water boil;
4) secondary soaks to decoct and extracts: soaked 1 hour with under the clear water room temperature of 5 times of former medicated powder weight by isolated medicine residue after first time soak extraction again, then to decoct extraction in 2 hours after water boil;
5) medicinal liquid is merged: after the decoction liquor of twice being separated with medicine residue, decoction liquor merged;
6) concentrated: the concentrated solution concentration of liquid medicine of merging being become 1 times of former medicated powder weight;
7) removal impurity is filtered;
8) subpackage can obtain Chinese medicine composition.
embodiment 2:
Identical with embodiment 1, institute's difference is, also add the 10g potassium sorbate and 10g sodium diacetate that use as antiseptic, preparation method, comprises the following steps:
1) sort: remove the impurity in each crude drug;
2) pulverize: each crude drug component is weighed and is ground into 200 object fine powders after mixing;
3) soak decoction to extract: soak under the clear water room temperature of the medicated powder 5 times of drug weight crushed 3 hours, then extract to decoct 2 hours after water boil;
4) secondary soaks to decoct and extracts: soaked 1 hour with under the clear water room temperature of 5 times of former medicated powder weight by isolated medicine residue after first time soak extraction again, then to decoct extraction in 2 hours after water boil;
5) medicinal liquid is merged: after the decoction liquor of twice being separated with medicine residue, decoction liquor merged;
6) concentrated: the concentrated solution concentration of liquid medicine of merging being become 1 times of former medicated powder weight;
7) removal impurity is filtered;
8) antiseptic is added;
9) subpackage can obtain Chinese medicine composition.
embodiment 3:
application Example:
Get crude drug 31.0kg altogether, the weight of each crude drug is respectively: Fructus Xanthii (stir-fry) 6.2 kg, Flos Magnoliae 6.2 kg, the Radix Angelicae Dahuricae 3.41 kg, Herba Asari 1.55 kg, Flos Chrysanthemi 3.41 kg, Herba Menthae 1.86 kg, Flos Lonicerae 3.41 kg, the Radix Astragali 3.41 kg, Radix Glycyrrhizae 1.55 kg.Through sorting, be ground into 200 object fine powders, soak under the clear water room temperature of medicated powder 5 times of drug weight of crushing and 155.0kg 3 hours, decoct and be separated medicinal liquid and medicine residue after 2 hours, leave and take medicinal liquid for subsequent use, soak 1 hour under more isolated medicine residue being added the clear water room temperature of 5 times of former medicated powder weight, decoct 2 hours, isolate medicinal liquid, the concentrated solution of 1 times of former medicated powder weight is condensed into after being mixed by the medicinal liquid of extracted twice, filter, add 3.1 g potassium sorbate and 3.1g sodium diacetate antiseptic, subpackage obtains finished product, is below embody rule situation:
(1) laying hen 4300 in 43 week age of feeding of broiler field, Yuzhong, Gansu county, has 60% appearance spirit depressed, and feather slightly disorderly, is curled up motionless, and poor appetite is even absolutely useless.Serosity or mucous secretions, facial edema and conjunctivitis is had in chicken group main manifestations nasal cavity and hole.Eye socket gathers tear bubble, and sneeze, ataxia, flows out mucus secretions in nose, and forms yellowish dry crusts at nares.Conjunctiva inflammation, eyelid swelled, the secreted thing adhesion of serious chicken eyelid can not be opened, even blind.Cut open hole and tunica mucosa tracheae generation acute catarrhal inflammation under inspection sick chicken visible nasal cavity, socket of the eye, under nasal cavity and socket of the eye, hole is full of water sample and even canescence liquid of vicidity, mucosa flushing, thickens.Lower jaw and facial area subcutaneous tissue thicken, the pathological changes of the typical infectious coryza of chicken such as gel-shaped edema.According to epidemiology, clinical symptoms, cut open inspection change and infectious coryza of chicken ELISA detect determine chicken group there occurs haemophilus paragallinarum infect, be diagnosed as chicken infect rhinitis.The Chinese herbal medicine extract preparation that application said method obtains is treated in the dilution of 1:50 ratio clear water, one day 2 times, is used in conjunction 5 days.Medication after 3 days symptom obviously alleviate, after 5 days whole chicken group spirit, search for food, drink water and all recover normal, the state of an illness obtains effective control, and cure rate is 87.2%, and effective percentage is 100%.
(2) 1200, Tianshui city broiler field laying hen generation infectious coryza of chicken, the Chinese herbal medicine extract preparation that application said method obtains is drunk to chicken according to after 1:50 thin up, every day 2 times, be used in conjunction 5 days, after medication, the 2nd day 70% sick chicken symptom obviously alleviates, within 4th day, the state of an illness is controlled, and cure rate is 90.4%, and effective percentage is 100%.
(3) 1500, Yongdeng County, Gansu Province broiler breeding field chicken generation infectious coryza of chicken, the Chinese herbal medicine extract preparation of the control infectious coryza of chicken that application said method obtains is drunk to chicken according to after 1:50 thin up, every day 2 times, be used in conjunction 2 days, the searching for food of chicken group, to drink water and mental status shape obtains obvious improvement, when the 5th day, the respiratory symptom of chicken group disappears, and the state of an illness is under control, cure rate is 89.9%, and effective percentage is 100%.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. for preventing and treating a Chinese medicine composition for infectious coryza of chicken, it is characterized in that, is prepared by the following crude drug according to parts by weight: parch Fructus Xanthii 20 parts, Flos Magnoliae 20 parts, the Radix Angelicae Dahuricae 11 parts, Herba Asari 5 parts, Flos Chrysanthemi 11 parts, Herba Menthae 6 parts, Flos Lonicerae 11 parts, the Radix Astragali 11 parts, 5 parts, Radix Glycyrrhizae.
2. a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken according to claim 1, is characterized in that, also include pharmaceutically acceptable antiseptic.
3. a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken according to claim 2, is characterized in that, described antiseptic is appropriate potassium sorbate and sodium diacetate.
4. the preparation method of a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken as described in as arbitrary in claim 1-3, is characterized in that, comprise the following steps:
1) sort: remove the impurity in each crude drug;
2) pulverize: each crude drug component is weighed and is ground into 200 object fine powders after mixing;
3) soak decoction to extract: soak under the clear water room temperature of the medicated powder 5 times of drug weight crushed 3 hours, then extract to decoct 2 hours after water boil;
4) secondary soaks to decoct and extracts: soaked 1 hour with under the clear water room temperature of 5 times of former medicated powder weight by isolated medicine residue after first time soak extraction again, then to decoct extraction in 2 hours after water boil;
5) medicinal liquid is merged: after the decoction liquor of twice being separated with medicine residue, decoction liquor merged;
6) concentrated: the concentrated solution concentration of liquid medicine of merging being become 1 times of former medicated powder weight;
7) removal impurity is filtered;
8) antiseptic is added;
9) subpackage can obtain Chinese medicine composition.
5. the application of a kind of Chinese medicine composition for preventing and treating infectious coryza of chicken as described in as arbitrary in claim 1-3 in the pharmaceutical preparation of preparation control infectious coryza of chicken.
6. application according to claim 5, is characterized in that, is drunk by Chinese medicine composition, 2 times on the one, be used in conjunction 3-5 day in after the ratio clear water dilution of 1:50 to chicken.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511916A (en) * | 2015-09-09 | 2017-03-22 | 谭慧敏 | Drug for treating chicken infectious rhinitis |
| CN110946919A (en) * | 2020-01-08 | 2020-04-03 | 河南大德广动物药业有限公司 | Traditional Chinese medicine composition for treating chicken rhinitis and preparation method thereof |
| CN114129619A (en) * | 2021-11-04 | 2022-03-04 | 瑞普（天津）生物药业有限公司 | Traditional Chinese medicine composition for preventing and treating infectious rhinitis of poultry and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101322759A (en) * | 2008-07-07 | 2008-12-17 | 张景峰 | Medicament for treating coryza and preparation thereof |
| CN102846713A (en) * | 2012-09-05 | 2013-01-02 | 河北科技师范学院 | Chinese herbal oral liquid for treating chicken infective rhinitis, and preparation method thereof |
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2015
- 2015-04-14 CN CN201510174276.6A patent/CN104825544B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101322759A (en) * | 2008-07-07 | 2008-12-17 | 张景峰 | Medicament for treating coryza and preparation thereof |
| CN102846713A (en) * | 2012-09-05 | 2013-01-02 | 河北科技师范学院 | Chinese herbal oral liquid for treating chicken infective rhinitis, and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 胡元亮: "《中兽医学》", 31 December 2006, 中国农业出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511916A (en) * | 2015-09-09 | 2017-03-22 | 谭慧敏 | Drug for treating chicken infectious rhinitis |
| CN110946919A (en) * | 2020-01-08 | 2020-04-03 | 河南大德广动物药业有限公司 | Traditional Chinese medicine composition for treating chicken rhinitis and preparation method thereof |
| CN114129619A (en) * | 2021-11-04 | 2022-03-04 | 瑞普（天津）生物药业有限公司 | Traditional Chinese medicine composition for preventing and treating infectious rhinitis of poultry and application thereof |
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