CN103735711B - Broiler chicken immunopotentiator - Google Patents
Broiler chicken immunopotentiator Download PDFInfo
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- CN103735711B CN103735711B CN201310682340.2A CN201310682340A CN103735711B CN 103735711 B CN103735711 B CN 103735711B CN 201310682340 A CN201310682340 A CN 201310682340A CN 103735711 B CN103735711 B CN 103735711B
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- 241000287828 Gallus gallus Species 0.000 title claims abstract description 36
- 230000000091 immunopotentiator Effects 0.000 title claims abstract description 21
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 47
- 241000411851 herbal medicine Species 0.000 claims abstract description 34
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 claims abstract description 16
- 241000756943 Codonopsis Species 0.000 claims abstract description 16
- 239000009636 Huang Qi Substances 0.000 claims abstract description 16
- FQPFAHBPWDRTLU-UHFFFAOYSA-N aminophylline Chemical compound NCCN.O=C1N(C)C(=O)N(C)C2=C1NC=N2.O=C1N(C)C(=O)N(C)C2=C1NC=N2 FQPFAHBPWDRTLU-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229960003556 aminophylline Drugs 0.000 claims abstract description 16
- 239000001099 ammonium carbonate Substances 0.000 claims abstract description 16
- 235000012501 ammonium carbonate Nutrition 0.000 claims abstract description 16
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 25
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 20
- 210000000582 semen Anatomy 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000005711 Benzoic acid Substances 0.000 claims description 10
- 235000010233 benzoic acid Nutrition 0.000 claims description 10
- 229960001617 ethyl hydroxybenzoate Drugs 0.000 claims description 10
- 235000010228 ethyl p-hydroxybenzoate Nutrition 0.000 claims description 10
- 239000004403 ethyl p-hydroxybenzoate Substances 0.000 claims description 10
- NUVBSKCKDOMJSU-UHFFFAOYSA-N ethylparaben Chemical compound CCOC(=O)C1=CC=C(O)C=C1 NUVBSKCKDOMJSU-UHFFFAOYSA-N 0.000 claims description 10
- 239000000706 filtrate Substances 0.000 claims description 10
- 238000009835 boiling Methods 0.000 claims description 7
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 5
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 5
- 238000000227 grinding Methods 0.000 claims description 5
- 235000011477 liquorice Nutrition 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 238000004064 recycling Methods 0.000 claims description 5
- 238000007873 sieving Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 4
- 239000012153 distilled water Substances 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 5
- 230000036039 immunity Effects 0.000 abstract description 4
- 206010061218 Inflammation Diseases 0.000 abstract description 3
- 201000010099 disease Diseases 0.000 abstract description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 3
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000555682 Forsythia x intermedia Species 0.000 abstract 1
- 240000004670 Glycyrrhiza echinata Species 0.000 abstract 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 abstract 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 abstract 1
- 244000274050 Platycodon grandiflorum Species 0.000 abstract 1
- 235000006753 Platycodon grandiflorum Nutrition 0.000 abstract 1
- 244000018633 Prunus armeniaca Species 0.000 abstract 1
- 235000009827 Prunus armeniaca Nutrition 0.000 abstract 1
- 241000405911 Rehmannia glutinosa Species 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 230000001524 infective effect Effects 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 229940010454 licorice Drugs 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 5
- 235000013330 chicken meat Nutrition 0.000 description 4
- 208000035473 Communicable disease Diseases 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 230000036737 immune function Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 241000271566 Aves Species 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 231100000678 Mycotoxin Toxicity 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 229960001438 immunostimulant agent Drugs 0.000 description 1
- 239000003022 immunostimulating agent Substances 0.000 description 1
- 230000003308 immunostimulating effect Effects 0.000 description 1
- 230000001506 immunosuppresive effect Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000002636 mycotoxin Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 239000012744 reinforcing agent Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A provided broiler chicken immunopotentiator comprises the following compositions: a Chinese herbal medicine concentrated solution, glycerin, ammonium carbonate, aminophylline and L-lactic acid, wherein the Chinese herbal medicine concentrated solution comprises licorice, raw rehmannia glutinosa, radix bupleuri, folium isatidis, radix astragali, forsythia suspense, platycodon grandiflorum, apricot kernel, dried orange peel and radix codonopsis. The immunopotentiator has the effects of resisting bacteria, diminishing inflammation, improving immunity and promoting broiler chicken growth, and is capable of effectively controlling generation of infective diseases and reducing broiler chicken mortality.
Description
Technical field
The present invention relates to birds practical technique field, particularly relate to a kind of broiler chicken immunopotentiator.
Background technology
The development of broiler breeding industry rapidly, the disease affecting broiler production and development is more come also many, in poultry husbandry, ubiquity infectious disease still outbreak of epidemic after immunity inoculation, and dosage strengthens and do not reach the situation of ideal treatment, and wherein one of reason is that immunologic function degression causes.Cause the factor of immunologic function degression as the application etc. of the impact of maternal antibody interference, malnutrition, immunosuppressive disease, Mycotoxins in Feed content overproof, stressors and hormonal medicaments, alkanisation disinfectant, and these factors are common in production.Effectively address this problem, just necessary activating immune system, makes chicken can obtain high-caliber immune response after vaccination.At present, chemicals para-immunity reinforcing agent also exists the drawback that toxic and side effects, drug residue and interim medication do not reach ideal effect all to some extent.
Summary of the invention
Object of the present invention is exactly defect for above-mentioned existence and provides a kind of broiler chicken immunopotentiator, the effect that this medicament has anti-inflammation, improves immunity, promotes growth of meat chicken, effectively can prevent and treat the generation of infectious disease, reduce broiler mortality rate.
A kind of broiler chicken immunopotentiator of the present invention, comprise following composition: Chinese herbal medicine concentrated solution, glycerol, ammonium carbonate, aminophylline, Pfansteihl, wherein, Radix Glycyrrhizae, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis is contained in Chinese herbal medicine concentrated solution.
Comprise following composition by weight: glycerol 5-12 part, ammonium carbonate 1-3 part, aminophylline 2-5 part, Pfansteihl 8-14 part, Radix Glycyrrhizae 3-6 part, Radix Rehmanniae 5-8 part, Radix Bupleuri 4-7 part, Folium Isatidis 7-9 part, Radix Astragali 3-8 part, Fructus Forsythiae 2-4 part, Radix Platycodonis 3-6 part, Semen Armeniacae Amarum 3-5 part, Pericarpium Citri Reticulatae 3-5 part, Radix Codonopsis 3-7 part.
The preparation process of Chinese herbal medicine concentrated solution is:
1. extracting liquorice, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis in proportion, grinding, crosses 80 mesh sieves;
2. add water after the Chinese herbal medicine mixing after sieving, water exceedes powder 2-3cm, after boiling 40 minutes, filters;
3. after concentrated for step filtrate 2., add ethanol to concentration of alcohol 60%, leave standstill 36 hours, filter, by concentrated after filtrate recycling ethanol, obtain Chinese herbal medicine concentrated solution.
This broiler chicken immunopotentiator is also containing ethylparaben 1-2 part, benzoic acid 0.5-1.5 part.
Boiled by Chinese herbal medicine concentrated solution after 10-20 minute and cool, slowly add glycerol, ammonium carbonate, aminophylline, Pfansteihl stirring successively, ethylparaben and benzoic acid dissolve and filter afterwards, and solubilizer obtains broiler chicken immunopotentiator to full dose.
Solvent is distilled water.
Chinese herbal medicine concentrated solution is cooled to 50 DEG C after boiling 10-20 minute.
Beneficial effect of the present invention is: comprise following composition: Chinese herbal medicine concentrated solution, glycerol, ammonium carbonate, aminophylline, Pfansteihl, wherein, Radix Glycyrrhizae, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis is contained in Chinese herbal medicine concentrated solution.
Under mutual coordinative role, broiler chicken immunopotentiator of the present invention, the effect having anti-inflammation, improve immunity, promote growth of meat chicken, takes to broiler for a long time, effectively can prevent and treat the generation of infectious disease, reduce broiler mortality rate, increase broiler and deliver for sale heavily, shorten marketing time, intestinal absorption is effective, Be very effective, strengthens broiler appetite, can ensure broiler normal growth.
Detailed description of the invention:
In order to understand the present invention better, describe technical scheme of the present invention in detail with instantiation below.
Embodiment 1
A kind of broiler chicken immunopotentiator of the present invention, comprise following composition: Chinese herbal medicine concentrated solution, glycerol, ammonium carbonate, aminophylline, Pfansteihl, wherein, Radix Glycyrrhizae, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis is contained in Chinese herbal medicine concentrated solution.
Each composition is by weight: glycerol 8 parts, ammonium carbonate 2 parts, aminophylline 3 parts, Pfansteihl 12 parts, 5 parts, Radix Glycyrrhizae, Radix Rehmanniae 7 parts, Radix Bupleuri 5 parts, Folium Isatidis 8 parts, the Radix Astragali 6 parts, Fructus Forsythiae 3 parts, Radix Platycodonis 5 parts, 4 parts, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae 4 parts, Radix Codonopsis 5 parts, ethylparaben 1 part, 1 part, benzoic acid.
The preparation process of Chinese herbal medicine concentrated solution is:
1. extracting liquorice, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis in proportion, grinding, crosses 80 mesh sieves;
2. add water after the Chinese herbal medicine mixing after sieving, water exceedes powder 2-3cm, after boiling 40 minutes, filters;
3. after concentrated for step filtrate 2., add ethanol to concentration of alcohol 60%, leave standstill 36 hours, filter, by concentrated after filtrate recycling ethanol, obtain Chinese herbal medicine concentrated solution.
50 DEG C are cooled to after Chinese herbal medicine concentrated solution is boiled 10-20 minute, slowly add glycerol, ammonium carbonate, aminophylline, Pfansteihl stirring successively, filter after ethylparaben and benzoic acid dissolve, and adding distil water obtains broiler chicken immunopotentiator A to full dose.
Embodiment 2
A kind of broiler chicken immunopotentiator of the present invention, comprise following composition: Chinese herbal medicine concentrated solution, glycerol, ammonium carbonate, aminophylline, Pfansteihl, wherein, Radix Glycyrrhizae, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis is contained in Chinese herbal medicine concentrated solution.
Each composition is by weight: glycerol 12 parts, ammonium carbonate 3 parts, aminophylline 5 parts, Pfansteihl 14 parts, 6 parts, Radix Glycyrrhizae, Radix Rehmanniae 8 parts, Radix Bupleuri 7 parts, Folium Isatidis 9 parts, the Radix Astragali 8 parts, Fructus Forsythiae 4 parts, Radix Platycodonis 6 parts, 5 parts, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae 5 parts, Radix Codonopsis 7 parts, ethylparaben 2 parts, 1.5 parts, benzoic acid.
The preparation process of Chinese herbal medicine concentrated solution is:
1. extracting liquorice, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis in proportion, grinding, crosses 80 mesh sieves;
2. add water after the Chinese herbal medicine mixing after sieving, water exceedes powder 2-3cm, after boiling 40 minutes, filters;
3. after concentrated for step filtrate 2., add ethanol to concentration of alcohol 60%, leave standstill 36 hours, filter, by concentrated after filtrate recycling ethanol, obtain Chinese herbal medicine concentrated solution.
50 DEG C are cooled to after Chinese herbal medicine concentrated solution is boiled 10-20 minute, slowly add glycerol, ammonium carbonate, aminophylline, Pfansteihl stirring successively, filter after ethylparaben and benzoic acid dissolve, and adding distil water obtains broiler chicken immunopotentiator B to full dose.
Embodiment 3
A kind of broiler chicken immunopotentiator of the present invention, comprise following composition: Chinese herbal medicine concentrated solution, glycerol, ammonium carbonate, aminophylline, Pfansteihl, wherein, Radix Glycyrrhizae, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis is contained in Chinese herbal medicine concentrated solution.
Each composition is by weight: glycerol 5 parts, ammonium carbonate 1 part, aminophylline 2 parts, Pfansteihl 8 parts, 3 parts, Radix Glycyrrhizae, Radix Rehmanniae 5 parts, Radix Bupleuri 4 parts, Folium Isatidis 7 parts, the Radix Astragali 3 parts, Fructus Forsythiae 2 parts, Radix Platycodonis 3 parts, 3 parts, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae 3 parts, Radix Codonopsis 3 parts, ethylparaben 1 part, 0.5 part, benzoic acid.
The preparation process of Chinese herbal medicine concentrated solution is:
1. extracting liquorice, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis in proportion, grinding, crosses 80 mesh sieves;
2. add water after the Chinese herbal medicine mixing after sieving, water exceedes powder 2-3cm, after boiling 40 minutes, filters;
3. after concentrated for step filtrate 2., add ethanol to concentration of alcohol 60%, leave standstill 36 hours, filter, by concentrated after filtrate recycling ethanol, obtain Chinese herbal medicine concentrated solution.
50 DEG C are cooled to after Chinese herbal medicine concentrated solution is boiled 10-20 minute, slowly add glycerol, ammonium carbonate, aminophylline, Pfansteihl stirring successively, filter after ethylparaben and benzoic acid dissolve, and adding distil water obtains broiler chicken immunopotentiator C to full dose.
Test is carried out in certain feeding of broiler field, adopt AA white meat-type chickens Seedling, divide 1,2,3,4 group, often organize broiler 2000, wherein 1,2,3 adopt broiler chicken immunopotentiator 2ml gavage every day of embodiment 1-3 once respectively, without immunostimulant, respectively organize nutritional labeling identical for the 4th group, feeding and management method is identical, and strict record.The results are shown in Table 1:
Table 1
Claims (3)
1. a broiler chicken immunopotentiator, it is characterized in that, be made up of the raw material of following weight ratio: glycerol 5-12 part, ammonium carbonate 1-3 part, aminophylline 2-5 part, Pfansteihl 8-14 part, Radix Glycyrrhizae 3-6 part, Radix Rehmanniae 5-8 part, Radix Bupleuri 4-7 part, Folium Isatidis 7-9 part, Radix Astragali 3-8 part, Fructus Forsythiae 2-4 part, Radix Platycodonis 3-6 part, Semen Armeniacae Amarum 3-5 part, Pericarpium Citri Reticulatae 3-5 part, Radix Codonopsis 3-7 part, ethylparaben 1-2 part, benzoic acid 0.5-1.5 part;
The preparation process of Chinese herbal medicine concentrated solution is:
1. extracting liquorice, Radix Rehmanniae, Radix Bupleuri, Folium Isatidis, the Radix Astragali, Fructus Forsythiae, Radix Platycodonis, Semen Armeniacae Amarum, Pericarpium Citri Reticulatae, Radix Codonopsis in proportion, grinding, crosses 80 mesh sieves;
2. add water after the Chinese herbal medicine mixing after sieving, water exceedes powder 2-3cm, after boiling 40 minutes, filters;
3. after concentrated for step filtrate 2., add ethanol to concentration of alcohol 60%, leave standstill 36 hours, filter, by concentrated after filtrate recycling ethanol, obtain Chinese herbal medicine concentrated solution;
Boiled by Chinese herbal medicine concentrated solution after 10-20 minute and cool, slowly add glycerol, ammonium carbonate, aminophylline, Pfansteihl stirring successively, ethylparaben and benzoic acid dissolve and filter afterwards, and solubilizer obtains broiler chicken immunopotentiator to full dose.
2. a kind of broiler chicken immunopotentiator according to claim 1, is characterized in that, solvent is distilled water.
3. a kind of broiler chicken immunopotentiator according to claim 1, is characterized in that, Chinese herbal medicine concentrated solution is cooled to 50 DEG C after boiling 10-20 minute.
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| CN103960475A (en) * | 2014-05-16 | 2014-08-06 | 四川农业大学 | Livestock heat stress-resisting Chinese herbal medicine additive |
| CN105311368B (en) * | 2014-08-13 | 2019-03-15 | 吴文超 | For putting the Chinese medicine composition of chicken nonreactive cultivation in a suitable place to breed |
| CN107251990A (en) * | 2017-05-25 | 2017-10-17 | 兰溪市沉默生物科技有限公司 | A kind of plant source reinforcing agent for lifting immunity |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1275386A (en) * | 2000-06-05 | 2000-12-06 | 塔志丽 | Pure traditional Chinese medicine fodder additives |
| CN1471836A (en) * | 2003-07-03 | 2004-02-04 | 中国农业科学院饲料研究所 | Birds feed additive |
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| CN1275386A (en) * | 2000-06-05 | 2000-12-06 | 塔志丽 | Pure traditional Chinese medicine fodder additives |
| CN1471836A (en) * | 2003-07-03 | 2004-02-04 | 中国农业科学院饲料研究所 | Birds feed additive |
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