CN103960475A - Livestock heat stress-resisting Chinese herbal medicine additive - Google Patents
Livestock heat stress-resisting Chinese herbal medicine additive Download PDFInfo
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Abstract
The invention discloses a livestock heat stress-resisting Chinese herbal medicine additive which is characterized by being prepared according to the following steps: taking 1-5 parts of hypericum monogynum, 1-5 parts of astragalus membranaceus, 5-10 parts of pig galls, 5-10 parts of liquorice, 2-6 parts of honeysuckle, 1-3 parts of rhizoma galangae, 1-2 parts of aminophylline, 1-2 parts of choline chloride, 1-2 parts of radix rehmanniae, 1-2 parts of radix bupleuri, 5-10 parts of folium isatidis, 5-10 parts of astragalus membranaceus, 5-10 parts of fructus forsythiae, 2-6 parts of platycodon grandiflorum, 10-15 parts of almonds and 10-15 parts of pericarpium citri reticulatae in parts by weight as raw materials, mixing, crushing, sterilizing, drying by cooling and then adding 20-40 parts of complex probiotics by weight.
Description
Technical field
The present invention relates to ruminant animal nutrition control technique and slowly-releasing technical field, belong to veterinary drug formulation art, particularly a kind of domestic animal anti-heat stress Chinese herb feed additive.
Background technology
Along with the pressure in demographic and economic, animal breeding index constantly tilts to high yield, and weather warms gradually in addition, the heat stress intensity that animal suffers is also increasing, especially milk cow, the nice and cool environment of happiness itself, the health damage that heat stress causes is larger, also maximum on the impact of production performance.Rank is carried out in the loss that the U.S. causes 10 kinds of farm-animals heat stresses, and it is the most serious that milk cow is affected by it, loses every year about 900,000,000 dollars.Although the not corresponding report of China, the lactation amount of southern milk cow generally, not as the north, also illustrates the adverse effect of heat stress to milk yield.Current research shows, the animal health damage main cause that heat stress causes is following two aspects: the one, and digestive tract function changes and causes a large amount of endotoxins to be absorbed into blood, and the 2nd, the aggravation of body oxidative damage.At present, domestic researchers extract volatile oil from have the plant of refrigerant effect, as the volatile oil in peppermint, Chinese cassia tree, cloves, by they in proportion compatibility be processed into heat stress fighting additive.The present invention has inherited forefathers and has used the thinking of this green non-pollution of herbaceous plant, in conjunction with front two main causes that cause heat stress damage of having addressed, considers the formula Design of product from anti-oxidant, intestinal endotoxin absorption and blood Endotoxin removal several respects.For this reason, we are taking Traditional Chinese Medicine heat-clearing theory as foundation, in conjunction with modern anti-oxidant and physical absorption theory, and with the Radix Astragali, the tuber of dwarf lilyturf, talcum, Radix Glycyrrhizae, the fruit of Chinese magnoliavine, vitamin E and vitamin C are that raw material carries out prescription, and improve formula taking results of animal as instructing.Experimental result according to us in cattle farm, in cow concentrate, add domestic animal anti-heat stress Chinese herb feed additive in the ratio of 200 grams/day, can obviously reduce heat stress cow serum cretinephosphokinase and serum cortisol, improve superoxide dismutase and activity of glutathione peroxidase, reduce MDA and endotoxin content, show that heat stress is alleviated, body anti-oxidation function is strengthened, and Endotoxin Damage reduces.Production performance index shows, uses domestic animal anti-heat stress Chinese herb feed additive to improve significantly milk production of cow by the utmost point, and feed intake is completely unaffected, and the price of deed significantly improves.Therefore, the present invention has significant economic benefit, social benefit and ecological benefits, and market prospects are wide.
Summary of the invention
The present invention is on the basis of Heat stress research, in conjunction with traditional Chinese medical science clearing away summerheat and the anti-oxidant theory of modern body, both considered to reduce endotoxin and absorbed, accelerate to remove the endotoxin that has been absorbed into blood, consider again to improve antioxidant ability of organism, to solving efficiently Heat stress problem.Technical problem to be solved by this invention is to provide a kind of domestic animal anti-heat stress Chinese herb feed additive, and this composite nutrient, for animal feed, can be improved to the utilization rate of protein, promotes growth of animals or poultry, strengthens livestock and poultry physique.
The present invention solves the scheme that its technical problem adopts: a kind of domestic animal anti-heat stress Chinese herb feed additive, it is characterized in that, and it is with Hypericum Chinense, the Radix Astragali, pig courage, Radix Glycyrrhizae, honeysuckle, galangal, aminophylline, Choline Chloride, radix rehmanniae recen, radix bupleuri, folium isatidis, the Radix Astragali, the capsule of weeping forsythia, balloonflower root, almond, dried orange peel is raw material, through mixing, pulverize, sterilization, after cool drying, add compound probiotic to make, described herbal raw material is by weight: Hypericum Chinense 1-5, Radix Astragali 1-5, pig courage 5-10, Radix Glycyrrhizae 5-10, honeysuckle 2-6, galangal 1-3, aminophylline 1-2, Choline Chloride 1-2, radix rehmanniae recen 1-2, radix bupleuri 1-2, folium isatidis 5-10, Radix Astragali 5-10, capsule of weeping forsythia 5-10, balloonflower root 2-6, almond 10-15, dried orange peel 10-15, described compound probiotic parts by weight are 20-40, the preparation process of additive is: raw material decontamination afterwash, segment, then grinds, and takes respectively by mass fraction, cleans and dries rear co-grinding, and the boiling that adds water, by the condensation of gas of evaporation, be dried to obtain concentrated powder, first raw material after treatment is extracted: the water extraction with 8 times of amounts of medicinal material is got, extraction temperature is 95-100 DEG C, and being adjusted to pH with 10% acid is for the first time 2-5, decocts 2 hours, extract for the second time and will water add to 8 times of medicinal material weight, with 10% alkali adjusting pH8-9, extraction time is 1.5 hours, and liquid filters respectively rear merging, and filtrate is concentrated into thick paste, thick paste carries out vacuum drying, pulverize, with the concentrated powder of 80～90% ethanolic solution lixiviate compound Chinese medicines, room temperature leaves standstill after layering, take out supernatant liquid and carry out after centrifugal, dry obtaining compound Chinese medicine extract, Chinese medical extract is mixed with compound probiotic.
The preparation of described compound probiotic nutrient solution: after water dissolves glucose, sucrose, potassium dihydrogen phosphate, add after bean cake powder, megasse mix and blend, in 120 DEG C of sterilizings 30 minutes, be cooled to 30 DEG C, access respectively bacillus subtilis, lactobacillus acidophilus, candida utili bacterium and excrement intestines ball slant strains and carry out pure culture, after cultivation finishes, mix by equal-volume, be mixed with compound probiotic nutrient solution; The preparation of composite probiotics ferment liquid: water adds after bean cake powder, megasse mix and blend after brown sugar, potassium dihydrogen phosphate are dissolved, and sterilizing 1 hour, is cooled to 30 DEG C, and access compound probiotic nutrient solution, obtains composite probiotics ferment liquid; The preparation of compound probiotic powder: by corn flour, bean cake powder mixing and stirring, after water dissolves brown sugar, in 100 DEG C of sterilizings 1 hour, treat that temperature is down to 30 DEG C, then after adding composite probiotics ferment liquid to mix, be evenly sprayed on the mixture of corn flour and bean cake powder and stir, make the mixture of corn flour and bean cake powder keep moisture, aerobic fermentation 5 days, and then anaerobic fermentation 2 days are dried and are pulverized to obtain compound probiotic powder at 50 DEG C of temperature; Other raw materials and compound probiotic powder are mixed in proportion and make composite nutrient, and described activation temperature is 30-34 DEG C, and described sterilising temp is 100-120 DEG C, and the temperature that described nutrient solution expands cultivation is again controlled at 30-32 DEG C; Preferably, described activation temperature is 30-32 DEG C, and described sterilising temp is 110-120 DEG C, and the temperature that described nutrient solution expands cultivation is again controlled at 30 DEG C.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described in detail, but the invention is not restricted to these embodiment:
Embodiment 1
A kind of domestic animal anti-heat stress Chinese herb feed additive, it is characterized in that, it is with Hypericum Chinense, the Radix Astragali, pig courage, Radix Glycyrrhizae, honeysuckle, galangal, aminophylline, Choline Chloride, radix rehmanniae recen, radix bupleuri, folium isatidis, the Radix Astragali, the capsule of weeping forsythia, balloonflower root, almond, dried orange peel is raw material, through mixing, pulverize, sterilization, after cool drying, add compound probiotic to make, described herbal raw material is by weight: Hypericum Chinense 1, the Radix Astragali 1, pig courage 5, Radix Glycyrrhizae 5, honeysuckle 2, galangal 1, aminophylline 1, Choline Chloride 1, radix rehmanniae recen 1, radix bupleuri 1, folium isatidis 5, the Radix Astragali 5, the capsule of weeping forsythia 5, balloonflower root 2, almond 10, dried orange peel 10, described compound probiotic parts by weight are 20.
The preparation process of additive is: raw material decontamination afterwash, segment, then grind, take respectively by mass fraction, clean dry after co-grinding, the boiling that adds water, by the condensation of gas of evaporation, dry to obtain concentrated powder; First raw material after treatment is extracted: the water extraction with 8 times of amounts of medicinal material is got, extraction temperature is 95-100 DEG C, and being adjusted to pH with 10% acid is for the first time 2-5, decocts 2 hours; Extract for the second time and will water add to 8 times of medicinal material weight, with 10% alkali adjusting pH8-9, extraction time is 1.5 hours, and liquid filters respectively rear merging, and filtrate is concentrated into thick paste, thick paste carries out vacuum drying, pulverize, with the concentrated powder of 80～90% ethanolic solution lixiviate compound Chinese medicines, room temperature leaves standstill after layering, take out supernatant liquid and carry out after centrifugal, dry obtaining compound Chinese medicine extract, Chinese medical extract is mixed with compound probiotic.
The preparation of compound probiotic nutrient solution: after water dissolves glucose, sucrose, potassium dihydrogen phosphate, add after bean cake powder, megasse mix and blend, in 120 DEG C of sterilizings 30 minutes, be cooled to 30 DEG C, access respectively bacillus subtilis, lactobacillus acidophilus, candida utili bacterium and excrement intestines ball slant strains and carry out pure culture, after cultivation finishes, mix by equal-volume, be mixed with compound probiotic nutrient solution; The preparation of composite probiotics ferment liquid: water adds after bean cake powder, megasse mix and blend after brown sugar, potassium dihydrogen phosphate are dissolved, and sterilizing 1 hour, is cooled to 30 DEG C, and access compound probiotic nutrient solution, obtains composite probiotics ferment liquid; The preparation of compound probiotic powder: by corn flour, bean cake powder mixing and stirring, after water dissolves brown sugar, in 100 DEG C of sterilizings 1 hour, treat that temperature is down to 30 DEG C, then after adding composite probiotics ferment liquid to mix, be evenly sprayed on the mixture of corn flour and bean cake powder and stir, make the mixture of corn flour and bean cake powder keep moisture, aerobic fermentation 5 days, and then anaerobic fermentation 2 days are dried and are pulverized to obtain compound probiotic powder at 50 DEG C of temperature; Other raw materials and compound probiotic powder are mixed in proportion and make composite nutrient, and described activation temperature is 30-34 DEG C, and described sterilising temp is 100-120 DEG C, and the temperature that described nutrient solution expands cultivation is again controlled at 30-32 DEG C; Preferably, described activation temperature is 30-32 DEG C, and described sterilising temp is 110-120 DEG C, and the temperature that described nutrient solution expands cultivation is again controlled at 30 DEG C.
In the time of summer high temperature to the domestic animal domestic animal anti-heat stress Chinese herb feed additive of feeding.Feed amount: no matter beef cattle or milk cow, 0.03% to 0.04% of the amount of the feeding percentage of liveweight of this additive, such as feed every day 150 to 200 grams of domestic animal anti-heat stress Chinese herb feed additives of the milk cow of 500 kilograms of: body weight.Usage: domestic animal anti-heat stress Chinese herb feed additive is participated in domestic animal fine fodder and fed.
Embodiment 2
A kind of domestic animal anti-heat stress Chinese herb feed additive, it is characterized in that, it is with Hypericum Chinense, the Radix Astragali, pig courage, Radix Glycyrrhizae, honeysuckle, galangal, aminophylline, Choline Chloride, radix rehmanniae recen, radix bupleuri, folium isatidis, the Radix Astragali, the capsule of weeping forsythia, balloonflower root, almond, dried orange peel is raw material, through mixing, pulverize, sterilization, after cool drying, add compound probiotic to make, described herbal raw material is by weight: Hypericum Chinense 5, the Radix Astragali 5, pig courage 10, Radix Glycyrrhizae 10, honeysuckle 6, galangal 3, aminophylline 2, Choline Chloride 2, radix rehmanniae recen 2, radix bupleuri 2, folium isatidis 10, the Radix Astragali 10, the capsule of weeping forsythia 10, balloonflower root 6, almond 15, dried orange peel 15, described compound probiotic parts by weight are 40.
The preparation process of additive is: raw material decontamination afterwash, segment, then grind, take respectively by mass fraction, clean dry after co-grinding, the boiling that adds water, by the condensation of gas of evaporation, dry to obtain concentrated powder; First raw material after treatment is extracted: the water extraction with 8 times of amounts of medicinal material is got, extraction temperature is 95-100 DEG C, and being adjusted to pH with 10% acid is for the first time 2-5, decocts 2 hours; Extract for the second time and will water add to 8 times of medicinal material weight, with 10% alkali adjusting pH8-9, extraction time is 1.5 hours, and liquid filters respectively rear merging, and filtrate is concentrated into thick paste, thick paste carries out vacuum drying, pulverize, with the concentrated powder of 80～90% ethanolic solution lixiviate compound Chinese medicines, room temperature leaves standstill after layering, take out supernatant liquid and carry out after centrifugal, dry obtaining compound Chinese medicine extract, Chinese medical extract is mixed with compound probiotic.
The preparation of compound probiotic nutrient solution: after water dissolves glucose, sucrose, potassium dihydrogen phosphate, add after bean cake powder, megasse mix and blend, in 120 DEG C of sterilizings 30 minutes, be cooled to 30 DEG C, access respectively bacillus subtilis, lactobacillus acidophilus, candida utili bacterium and excrement intestines ball slant strains and carry out pure culture, after cultivation finishes, mix by equal-volume, be mixed with compound probiotic nutrient solution; The preparation of composite probiotics ferment liquid: water adds after bean cake powder, megasse mix and blend after brown sugar, potassium dihydrogen phosphate are dissolved, and sterilizing 1 hour, is cooled to 30 DEG C, and access compound probiotic nutrient solution, obtains composite probiotics ferment liquid; The preparation of compound probiotic powder: by corn flour, bean cake powder mixing and stirring, after water dissolves brown sugar, in 100 DEG C of sterilizings 1 hour, treat that temperature is down to 30 DEG C, then after adding composite probiotics ferment liquid to mix, be evenly sprayed on the mixture of corn flour and bean cake powder and stir, make the mixture of corn flour and bean cake powder keep moisture, aerobic fermentation 5 days, and then anaerobic fermentation 2 days are dried and are pulverized to obtain compound probiotic powder at 50 DEG C of temperature; Other raw materials and compound probiotic powder are mixed in proportion and make composite nutrient, and described activation temperature is 30-34 DEG C, and described sterilising temp is 100-120 DEG C, and the temperature that described nutrient solution expands cultivation is again controlled at 30-32 DEG C; Preferably, described activation temperature is 30-32 DEG C, and described sterilising temp is 110-120 DEG C, and the temperature that described nutrient solution expands cultivation is again controlled at 30 DEG C.
Claims (3)
1. a domestic animal anti-heat stress Chinese herb feed additive, it is characterized in that, it is with Hypericum Chinense, the Radix Astragali, pig courage, Radix Glycyrrhizae, honeysuckle, galangal, aminophylline, Choline Chloride, radix rehmanniae recen, radix bupleuri, folium isatidis, the Radix Astragali, the capsule of weeping forsythia, balloonflower root, almond, dried orange peel is raw material, through mixing, pulverize, sterilization, after cool drying, add compound probiotic to make, described herbal raw material is by weight: Hypericum Chinense 1-5, Radix Astragali 1-5, pig courage 5-10, Radix Glycyrrhizae 5-10, honeysuckle 2-6, galangal 1-3, aminophylline 1-2, Choline Chloride 1-2, radix rehmanniae recen 1-2, radix bupleuri 1-2, folium isatidis 5-10, Radix Astragali 5-10, capsule of weeping forsythia 5-10, balloonflower root 2-6, almond 10-15, dried orange peel 10-15, described compound probiotic parts by weight are 20-40.
2. according to domestic animal anti-heat stress Chinese herb feed additive claimed in claim 1, it is characterized in that, the preparation process of additive is: raw material decontamination afterwash, segment, then grind, take respectively by mass fraction, clean dry after co-grinding, the boiling that adds water, by the condensation of gas of evaporation, dry to obtain concentrated powder; First raw material after treatment is extracted: the water extraction with 8 times of amounts of medicinal material is got, extraction temperature is 95-100 DEG C, and being adjusted to pH with 10% acid is for the first time 2-5, decocts 2 hours; Extract for the second time and will water add to 8 times of medicinal material weight, with 10% alkali adjusting pH8-9, extraction time is 1.5 hours, and liquid filters respectively rear merging, and filtrate is concentrated into thick paste, thick paste carries out vacuum drying, pulverize, with the concentrated powder of 80～90% ethanolic solution lixiviate compound Chinese medicines, room temperature leaves standstill after layering, take out supernatant liquid and carry out after centrifugal, dry obtaining compound Chinese medicine extract, Chinese medical extract is mixed with compound probiotic.
3. according to domestic animal anti-heat stress Chinese herb feed additive claimed in claim 1, it is characterized in that, the preparation of compound probiotic nutrient solution: after water dissolves glucose, sucrose, potassium dihydrogen phosphate, add after bean cake powder, megasse mix and blend, in 120 DEG C of sterilizings 30 minutes, be cooled to 30 DEG C, access respectively bacillus subtilis, lactobacillus acidophilus, candida utili bacterium and excrement intestines ball slant strains and carry out pure culture, after cultivation finishes, mix by equal-volume, be mixed with compound probiotic nutrient solution; The preparation of composite probiotics ferment liquid: water adds after bean cake powder, megasse mix and blend after brown sugar, potassium dihydrogen phosphate are dissolved, and sterilizing 1 hour, is cooled to 30 DEG C, and access compound probiotic nutrient solution, obtains composite probiotics ferment liquid; The preparation of compound probiotic powder: by corn flour, bean cake powder mixing and stirring, after water dissolves brown sugar, in 100 DEG C of sterilizings 1 hour, treat that temperature is down to 30 DEG C, then after adding composite probiotics ferment liquid to mix, be evenly sprayed on the mixture of corn flour and bean cake powder and stir, make the mixture of corn flour and bean cake powder keep moisture, aerobic fermentation 5 days, and then anaerobic fermentation 2 days are dried and are pulverized to obtain compound probiotic powder at 50 DEG C of temperature; Other raw materials and compound probiotic powder are mixed in proportion and make composite nutrient, and described activation temperature is 30-34 DEG C, and described sterilising temp is 100-120 DEG C, and the temperature that described nutrient solution expands cultivation is again controlled at 30-32 DEG C; Preferably, described activation temperature is 30-32 DEG C, and described sterilising temp is 110-120 DEG C, and the temperature that described nutrient solution expands cultivation is again controlled at 30 DEG C.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104322963A (en) * | 2014-10-22 | 2015-02-04 | 张淑二 | Compound feed for mutton sheep at fattening period and preparation method of compound feed |
| CN104686800A (en) * | 2015-01-29 | 2015-06-10 | 金华傲农生物科技有限公司 | Feed additive for reducing stress of sows and preparation method thereof |
| CN107594154A (en) * | 2017-10-17 | 2018-01-19 | 肖秋花 | A kind of beef cattle anti-heat stress feed and preparation method thereof |
| CN108112776A (en) * | 2017-09-15 | 2018-06-05 | 普乐格（厦门）生物科技有限公司 | It is a kind of for microorganism formulation of animal and bird intestines injury repair and preparation method thereof |
| CN110731282A (en) * | 2019-11-26 | 2020-01-31 | 上海泓宝绿色水产股份有限公司 | sprinkling summer-heat-relieving bacteria |
| CN110916014A (en) * | 2019-11-26 | 2020-03-27 | 上海泓宝绿色水产股份有限公司 | Oral sunstroke prevention bacterium |
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| CN103735711A (en) * | 2013-12-12 | 2014-04-23 | 济南新起点医药科技有限公司 | Broiler chicken immunopotentiator |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104322963A (en) * | 2014-10-22 | 2015-02-04 | 张淑二 | Compound feed for mutton sheep at fattening period and preparation method of compound feed |
| CN104686800A (en) * | 2015-01-29 | 2015-06-10 | 金华傲农生物科技有限公司 | Feed additive for reducing stress of sows and preparation method thereof |
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| CN107594154A (en) * | 2017-10-17 | 2018-01-19 | 肖秋花 | A kind of beef cattle anti-heat stress feed and preparation method thereof |
| CN110731282A (en) * | 2019-11-26 | 2020-01-31 | 上海泓宝绿色水产股份有限公司 | sprinkling summer-heat-relieving bacteria |
| CN110916014A (en) * | 2019-11-26 | 2020-03-27 | 上海泓宝绿色水产股份有限公司 | Oral sunstroke prevention bacterium |
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Application publication date: 20140806 |