CN105194361A - Traditional Chinese medicine composition for preventing and treating hemorrhagic disease of aquatic animals and preparation method thereof - Google Patents
Traditional Chinese medicine composition for preventing and treating hemorrhagic disease of aquatic animals and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for preventing and treating the hemorrhagic disease of aquatic animals and a preparation method thereof. The traditional Chinese medicine composition comprises the following ingredients in parts by weight: 29-35 parts of astragalus membranaceus, 19-22 parts of hairyvein agrimonia herb and bud, 19-22 parts of lalang grass rhizome, 9-12 parts of carbonized folium artemisiae argyi, 9-12 parts of portulaca oleracea and 9-12 parts of stir-fried cattail pollen and is prepared through the decocting method. According to the traditional Chinese medicine composition, the traditional Chinese medicines are combined reasonably and cooperate with one another, so that the traditional Chinese medicine composition has the efficacy of stopping bleeding by astringency, removing blood stasis and removing swelling and strengths immunity simultaneously; an effective treatment medicine for preventing and treating hemorrhagic disease of the aquatic animals is provided for the aquaculture industry; the traditional Chinese medicine composition has the characteristics of quick action, exact curative effect, no medicine residue, low possibility of drug resistance and no any toxic or side effect; the preparation method is simple and needs of scale industrial production are met.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, especially a kind ofly prevent and treat Chinese medicine composition of Aquatic product animal bleeds disease and preparation method thereof.
Background technology
In field of aquaculture, fish bacterial hemorrhagic disease is also called bacterial septicemia and explosive hemorrhagic disease etc., is China's harm fish most species, Prevalent district is the widest, cause damage maximum a kind of acute infectious disease.Bacterial haemorrhage disease relates to kind Cyprinus carpio, Carassius auratus, Megalobrama amblycephala, Hypophthalmichthys molitrix, Aristichthys nobilis, bream, Ctenopharyngodon idellus, Monopterus albus (Zuiew) etc., the whole nation 20 Duo Ge provinces and cities, autonomous region's this disease popular, epidemic season from late February to by the end of November, water temperature at 6-9 DEG C, by the most serious about 28 DEG C morbidities with water temperature.Show according to investigations, sickness rate is 60-70%, and mortality rate is 10-20%, falls ill serious to reach 100%, and therefore this disease economic loss of causing to aquaculture of aquatic animal family is very serious.
The hemorrhagic disease of Fish has viral hemorrhagic disease and the sick two kinds of situations of bacterial haemorrhage, and bacterial haemorrhage is sick sick higher than viral hemorrhagic all far away in frequency of disease development and the extent of injury.The Symptoms variation of bacterial haemorrhage disease, morbidity is anxious, infection is fast, fashionable colors is long, and mortality rate is high, loss large.The lighter stops eating, stop long, sporadicly death, the large quantities of death of severe one, and once morbidity is difficult to control, the state of an illness easily repeatedly.To this, originally taked the Western medicine such as amantadine or ribavirin to treat for viral disease people, but country expressly prohibit the use this type of medicine at present; And for bacterial haemorrhage disease by after western medicine, the state of an illness still easily recurs, or a drug withdrawal state of an illness can increase the weight of again, can not reach the effect of healing.Not yet find at present to treat the medicine of the hemorrhagic disease of fish caused due to above-mentioned two kinds of reasons simultaneously.Visible, aquatic animal hemorrhagic disease has become the content that current numerous aquaculturists and related researcher show great attention to.Therefore, a kind of Chinese medicine preparation preventing and treating Aquatic product animal bleeds disease of Chinese herbal medicine resource research and development making full use of China's abundant has very important production practices meaning.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine composition preventing and treating Aquatic product animal bleeds disease.
Another technical problem to be solved by this invention is the preparation method of the Chinese medicine composition providing above-mentioned control Aquatic product animal bleeds disease.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine composition preventing and treating Aquatic product animal bleeds disease, be made up of the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry), by its weight parts Radix Astragali 29-35 part, Herba Agrimoniae 19-22 part, Rhizoma Imperatae 19-22 part, Folium Artemisiae Argyi (charcoal) 9-12 part, Herba Portulacae 9-12 part, Pollen Typhae (stir-fry) 9-12 part.
Preferably, the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, is obtained by following method:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 100-300 mesh sieve;
(2) take Radix Astragali 29-35 part by weight, Herba Agrimoniae 19-22 part, Rhizoma Imperatae 19-22 part, Folium Artemisiae Argyi (charcoal) 9-12 part, Herba Portulacae 9-12 part, Pollen Typhae (stir-fry) 9-12 part is raw material;
(3) water adding medical material gross weight 10-15 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 10-15 times amount carries out water extraction, Extracting temperature is 80 DEG C, extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) supernatant concentration merged in step (4) is obtained clear paste.
Preferably, the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, in described step (5), the relative density of clear paste is 1.20 ~ 1.25.
Preferably, the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, by its weight parts Radix Astragali 29-33 part, Herba Agrimoniae 19-21 part, Rhizoma Imperatae 20-21 part, Folium Artemisiae Argyi (charcoal) 10-11 part, Herba Portulacae 10-11 part, Pollen Typhae (stir-fry) 10-11 part.
Preferably, the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, by its weight parts Radix Astragali 30 parts, Herba Agrimoniae 20 parts, Rhizoma Imperatae 20 parts, Folium Artemisiae Argyi (charcoal) 10 parts, Herba Portulacae 10 parts, Pollen Typhae (stir-fry) 10 parts.
The preparation method of the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, concrete preparation process is as follows:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 100-300 mesh sieve;
(2) take Radix Astragali 29-35 part by weight, Herba Agrimoniae 19-22 part, Rhizoma Imperatae 19-22 part, Folium Artemisiae Argyi (charcoal) 9-12 part, Herba Portulacae 9-12 part, Pollen Typhae (stir-fry) 9-12 part is raw material;
(3) water adding medical material gross weight 10-15 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 10-15 times amount carries out water extraction, Extracting temperature is 80 DEG C, extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) supernatant concentration merged in step (4) is obtained clear paste.
Preferably, the preparation method of the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, in described step (5), the relative density of clear paste is 1.20 ~ 1.25.
Preferably, the preparation method of the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, in described step (5), the relative density of clear paste is 1.23.
Above-mentioned relative density refers to the proportion of this clear paste.
The invention has the beneficial effects as follows:
The Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, by Chinese medicine reasonable formula, mutual Synergistic, there is effect of astringing to arrest bleeding, loose blood detumescence, enhancing immunity simultaneously, for culture fishery provides a kind of effective medicine preventing and treating Aquatic product animal bleeds disease, have instant effect, curative effect really, no drug residue, not easily produce drug resistance, feature without any side effects; Its preparation method is simple, is applicable to the needs that large-scale industrial is produced.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme of the present invention is further described.
Embodiment 1
A kind of Chinese medicine composition preventing and treating Aquatic product animal bleeds disease, be made up of the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry), wherein Radix Astragali 30g, Herba Agrimoniae 20g, Rhizoma Imperatae 20g, Folium Artemisiae Argyi (charcoal) 10g, Herba Portulacae 10g, Pollen Typhae (stir-fry) 10g.
The preparation method of the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, concrete preparation process is as follows:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 200 mesh sieves;
(2) take Radix Astragali 30g, Herba Agrimoniae 20g, Rhizoma Imperatae 20g, Folium Artemisiae Argyi (charcoal) 10g, Herba Portulacae 10g, Pollen Typhae (stir-fry) 10g be raw material;
(3) water adding medical material gross weight 13 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 12 times amount carries out water extraction, and Extracting temperature is 80 DEG C, and extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) be 1.23 by the supernatant concentration that merges in step (4) to relative density, obtain clear paste.
Embodiment 2
A kind of Chinese medicine composition preventing and treating Aquatic product animal bleeds disease, be made up of the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry), wherein Radix Astragali 29g, Herba Agrimoniae 22g, Rhizoma Imperatae 22g, Folium Artemisiae Argyi (charcoal) 9g, Herba Portulacae 9g, Pollen Typhae (stir-fry) 12g.
The preparation method of the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, concrete preparation process is as follows:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 300 mesh sieves;
(2) take Radix Astragali 29g, Herba Agrimoniae 22g, Rhizoma Imperatae 22g, Folium Artemisiae Argyi (charcoal) 9g, Herba Portulacae 9g, Pollen Typhae (stir-fry) 12g be raw material;
(3) water adding medical material gross weight 15 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 10 times amount carries out water extraction, and Extracting temperature is 80 DEG C, and extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) be 1.25 by the supernatant concentration that merges in step (4) to relative density, obtain clear paste.
Embodiment 3
A kind of Chinese medicine composition preventing and treating Aquatic product animal bleeds disease, be made up of the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry), wherein Radix Astragali 35g, Herba Agrimoniae 19g, Rhizoma Imperatae 19g, Folium Artemisiae Argyi (charcoal) 12g, Herba Portulacae 12g, Pollen Typhae (stir-fry) 9g.
The preparation method of the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, concrete preparation process is as follows:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 100 mesh sieves;
(2) take Radix Astragali 35g, Herba Agrimoniae 19g, Rhizoma Imperatae 19g, Folium Artemisiae Argyi (charcoal) 12g, Herba Portulacae 12g, Pollen Typhae (stir-fry) 9g be raw material;
(3) water adding medical material gross weight 10 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 15 times amount carries out water extraction, and Extracting temperature is 80 DEG C, and extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) be 1.20 by the supernatant concentration that merges in step (4) to relative density, obtain clear paste.
Embodiment 4
A kind of Chinese medicine composition preventing and treating Aquatic product animal bleeds disease, be made up of the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry), wherein Radix Astragali 33g, Herba Agrimoniae 19g, Rhizoma Imperatae 20g, Folium Artemisiae Argyi (charcoal) 11g, Herba Portulacae 11g, Pollen Typhae (stir-fry) 10g.
The preparation method of the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, concrete preparation process is as follows:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 160 mesh sieves;
(2) take Radix Astragali 33g, Herba Agrimoniae 19g, Rhizoma Imperatae 20g, Folium Artemisiae Argyi (charcoal) 11g, Herba Portulacae 11g, Pollen Typhae (stir-fry) 10g be raw material;
(3) water adding medical material gross weight 14 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 14 times amount carries out water extraction, and Extracting temperature is 80 DEG C, and extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) be 1.22 by the supernatant concentration that merges in step (4) to relative density, obtain clear paste.
Embodiment 5
A kind of Chinese medicine composition preventing and treating Aquatic product animal bleeds disease, be made up of the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry), wherein Radix Astragali 29g, Herba Agrimoniae 21g, Rhizoma Imperatae 21g, Folium Artemisiae Argyi (charcoal) 10g, Herba Portulacae 10g, Pollen Typhae (stir-fry) 11g.
The preparation method of the Chinese medicine composition of above-mentioned control Aquatic product animal bleeds disease, concrete preparation process is as follows:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 240 mesh sieves;
(2) take Radix Astragali 29g, Herba Agrimoniae 21g, Rhizoma Imperatae 21g, Folium Artemisiae Argyi (charcoal) 10g, Herba Portulacae 10g, Pollen Typhae (stir-fry) 11g be raw material;
(3) water adding medical material gross weight 12 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 11 times amount carries out water extraction, and Extracting temperature is 80 DEG C, and extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) be 1.24 by the supernatant concentration that merges in step (4) to relative density, obtain clear paste.
The described Chinese crude drug of one of embodiment 1-5 is commercially available prod, and each amounts of components increased according to same ratio or reduce, the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The described Chinese crude drug of one of embodiment 1-5 all meets " Chinese veterinary pharmacopoeia " version two ministerial standard in 2010.
The composition principle of Chinese medicine composition of the present invention is: Radix Astragali sweet in the mouth, slightly warm in nature in side, enter spleen channel, can available protecting liver, has and prevent and treat hepatic necrosis, enhancing human body immunity function, blood vessel dilating, reduce blood pressure to effects such as antiplatelet aggregation; Rhizoma Imperatae sweet in the mouth, cold in nature, enter stomach, urinary bladder channel, use same with the Radix Astragali, cold Wen Xiangji, QI invigorating diuresis, enhancing human body immunity ability; Herba Agrimoniae bitter in the mouth, puckery, property is put down, and enters liver, spleen channel, has astringing to arrest bleeding, dispersing swelling and dissipating binds effect, play good hemostatic and antibacterial effect with Rhizoma Imperatae compatibility; Folium Artemisiae Argyi acrid in the mouth, hardship, warm in nature, enter liver,spleen,kidney warp, chemical composition in Folium Artemisiae Argyi contains volatile oil, sesquiterpenoids, ring wood bornane alcohol type triterpene and flavone compound, Folium Artemisiae Argyi can shorten clotting time, strengthen by anastalsis after traditional concocted method charcoal processing, Folium Artemisiae Argyi has choleretic effect, the effect such as antimutagenesis, calmness; Pollen Typhae (stir-fry) sweet in the mouth, property are flat, enter liver, heart channel, have the merit of hemostasia and dissipation blood stasis pain relieving, and sweet slow property is put down, and can stop blooding excessive, again can promoting the circulation of blood stagnant, holding concurrently can dispelling the stagnated QI knot, qualcomm meridian; Herba Portulacae is cold in nature, sweet in the mouth is sour, and enter the heart, liver, spleen, large intestine channel, heat-clearing and toxic substances removing, diuretic dries, loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, hemostasis removing heat from blood.All medicines share, mutual Synergistic, remarkably productive to control Aquatic product animal bleeds disease, especially adopt proportioning described in embodiment 1, and effect of astringing to arrest bleeding, loose blood detumescence is very remarkable, is particularly applicable to the control of aquatic animal hemorrhagic disease.
Clinical trial example:
Jinghai plant master supports Ctenopharyngodon idellus, July, Ctenopharyngodon idellus broke out large-area hemorrhagic disease, during early stage actute infection, the upper lower jaw of sick fish, oral cavity, the gill cover, eyes, fin base and fish body both sides mild hyperaemia, serious seasonal disease fish body surface is serious congested so that hemorrhage, congested around eye socket, exophthalmos, anus is red and swollen, abdominal part expands, and abdominal cavity inner product has pale yellow transparent or the muddy ascites of bronzing, and enteral does not have food, and have more mucus, intestinal is swollen, and also have part flap to hold up, gill filament end rots, flush, fish glue wall is congested.
Chinese medicine composition described in the embodiment of the present invention 1 is mixed by per kilogram feedstuff and takes this Chinese medicine composition 20 grams, be selected in every day 2 times time that fish is the most vigorous, being used in conjunction 3-5 days was 1 course for the treatment of, was splashed by this Chinese medicine composition directly to pond simultaneously, and consumption is 1.5-2.5kg/ mu water body.After using 2 courses for the treatment of, the transference cure of sick fish hemorrhagic disease, is almost recovered, and ingests normal.
This Chinese medicine composition of rear employing proceeds the prevention of hemorrhagic disease, and every two weeks uses once, and splashed directly to pond by this Chinese medicine composition according to the consumption of 1.5-2.5kg/ mu water body, sickness rate comparatively reduces by 26% the same period in former years.
Above-mentioned reference embodiment is to this kind of detailed description of preventing and treating Chinese medicine composition of Aquatic product animal bleeds disease and preparation method thereof and carrying out; illustrative instead of determinate; several embodiments can be listed according to institute's limited range; therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (8)
1. prevent and treat Chinese medicine composition of Aquatic product animal bleeds disease and preparation method thereof for one kind, it is characterized in that: be made up of the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry), by its weight parts Radix Astragali 29-35 part, Herba Agrimoniae 19-22 part, Rhizoma Imperatae 19-22 part, Folium Artemisiae Argyi (charcoal) 9-12 part, Herba Portulacae 9-12 part, Pollen Typhae (stir-fry) 9-12 part.
2. the Chinese medicine composition of control Aquatic product animal bleeds disease according to claim 1, is characterized in that: obtained by following method:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 100-300 mesh sieve;
(2) take Radix Astragali 29-35 part by weight, Herba Agrimoniae 19-22 part, Rhizoma Imperatae 19-22 part, Folium Artemisiae Argyi (charcoal) 9-12 part, Herba Portulacae 9-12 part, Pollen Typhae (stir-fry) 9-12 part is raw material;
(3) water adding medical material gross weight 10-15 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 10-15 times amount carries out water extraction, Extracting temperature is 80 DEG C, extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) supernatant concentration merged in step (4) is obtained clear paste.
3. the Chinese medicine composition of control Aquatic product animal bleeds disease according to claim 2, is characterized in that: in described step (5), the relative density of clear paste is 1.20 ~ 1.25.
4. the Chinese medicine composition of control Aquatic product animal bleeds disease according to claim 1 and 2, is characterized in that: by its weight parts Radix Astragali 29-33 part, Herba Agrimoniae 19-21 part, Rhizoma Imperatae 20-21 part, Folium Artemisiae Argyi (charcoal) 10-11 part, Herba Portulacae 10-11 part, Pollen Typhae (stir-fry) 10-11 part.
5. the Chinese medicine composition of control Aquatic product animal bleeds disease according to claim 4, is characterized in that: by its weight parts Radix Astragali 30 parts, Herba Agrimoniae 20 parts, Rhizoma Imperatae 20 parts, Folium Artemisiae Argyi (charcoal) 10 parts, Herba Portulacae 10 parts, Pollen Typhae (stir-fry) 10 parts.
6. the preparation method of the Chinese medicine composition of the control Aquatic product animal bleeds disease that one of claim 1-5 is described, is characterized in that: concrete preparation process is as follows:
(1) respectively the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) are carried out micronizing, cross 100-300 mesh sieve;
(2) take Radix Astragali 29-35 part by weight, Herba Agrimoniae 19-22 part, Rhizoma Imperatae 19-22 part, Folium Artemisiae Argyi (charcoal) 9-12 part, Herba Portulacae 9-12 part, Pollen Typhae (stir-fry) 9-12 part is raw material;
(3) water adding medical material gross weight 10-15 times amount after the Radix Astragali, Herba Agrimoniae, Rhizoma Imperatae, Folium Artemisiae Argyi (charcoal), Herba Portulacae and Pollen Typhae (stir-fry) mixing is carried out water extraction, Extracting temperature is 80 DEG C, extraction time is 4 hours, after static 12 hours, gets supernatant for subsequent use;
(4) water that in step (3), remaining Chinese medicine filtering residue continues to add this Chinese medicine filtering residue gross weight 10-15 times amount carries out water extraction, Extracting temperature is 80 DEG C, extraction time is 2 hours, leave standstill after 6 hours, get supernatant, merge with the supernatant in step (3), mix homogeneously;
(5) supernatant concentration merged in step (4) is obtained clear paste.
7. the preparation method of the Chinese medicine composition of control Aquatic product animal bleeds disease according to claim 6, is characterized in that: in described step (5), the relative density of clear paste is 1.20 ~ 1.25.
8. the preparation method of the Chinese medicine composition of the control Aquatic product animal bleeds disease according to claim 6 or 7, is characterized in that: in described step (5), the relative density of clear paste is 1.23.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816538A (en) * | 2016-05-19 | 2016-08-03 | 孙克林 | Composition for treating fulminant hemorrhagic disease of crucian carps |
| CN114887007A (en) * | 2022-05-13 | 2022-08-12 | 山西省水产技术推广服务中心 | Traditional Chinese medicine composition for preventing and treating bighead carp bleeding disease, feed, preparation method and application thereof |
| CN114917300A (en) * | 2022-07-11 | 2022-08-19 | 甘肃农业大学 | Traditional Chinese medicine composition for preventing and treating streptococcicosis of aquatic animals |
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| JP2012036147A (en) * | 2010-08-10 | 2012-02-23 | En Otsuka Pharmaceutical Co Ltd | Agent for improving cerebrovascular disorder |
| CN103599392A (en) * | 2013-12-02 | 2014-02-26 | 郝智慧 | Forage for controlling hemorragic disease of grass carp |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2012036147A (en) * | 2010-08-10 | 2012-02-23 | En Otsuka Pharmaceutical Co Ltd | Agent for improving cerebrovascular disorder |
| CN103599392A (en) * | 2013-12-02 | 2014-02-26 | 郝智慧 | Forage for controlling hemorragic disease of grass carp |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816538A (en) * | 2016-05-19 | 2016-08-03 | 孙克林 | Composition for treating fulminant hemorrhagic disease of crucian carps |
| CN114887007A (en) * | 2022-05-13 | 2022-08-12 | 山西省水产技术推广服务中心 | Traditional Chinese medicine composition for preventing and treating bighead carp bleeding disease, feed, preparation method and application thereof |
| CN114887007B (en) * | 2022-05-13 | 2023-04-18 | 山西省水产技术推广服务中心 | Traditional Chinese medicine composition for preventing and treating bighead carp bleeding disease, feed, and preparation method and application thereof |
| CN114917300A (en) * | 2022-07-11 | 2022-08-19 | 甘肃农业大学 | Traditional Chinese medicine composition for preventing and treating streptococcicosis of aquatic animals |
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Application publication date: 20151230 |