CN105816538A - Composition for treating fulminant hemorrhagic disease of crucian carps - Google Patents

Composition for treating fulminant hemorrhagic disease of crucian carps Download PDF

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CN105816538A
CN105816538A CN201610339073.2A CN201610339073A CN105816538A CN 105816538 A CN105816538 A CN 105816538A CN 201610339073 A CN201610339073 A CN 201610339073A CN 105816538 A CN105816538 A CN 105816538A
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hemorrhagic disease
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孙克林
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A61K36/855—Clerodendrum, e.g. glorybower
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/86—Violaceae (Violet family)

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Abstract

The invention belongs to the field of aquaculture, and particularly discloses a composition for treating a fulminant hemorrhagic disease of crucian carps .The composition is prepared from, by mass, 11-16 parts of smut fungi of rice, 9-15 parts of small herba portulacae and 5-7 parts of roots of thalictrum delavayi Franch. .The cure rate of the composition on enteritis of the crucian carps can reach 85% or above.

Description

A kind of compositions treating Carassius auratus burst hemorrhagic disease
Technical field
The present invention relates to aquaculture field, be specifically related to a kind of compositions treating Carassius auratus burst hemorrhagic disease.
Background technology
Carassius auratus burst hemorrhagic disease is onset peak in annual 6-9 month, and its disease time is short, mortality rate is high.Carassius auratus is ill Initial stage, fish body both sides, eye socket, the gill cover, fin etc. mild hyperaemia.When being in a bad way, body surface and fin are the most congested, eye socket week Enclosing hyperemia, some fish exophthalmos, have faint yellow ascites or red muddy ascites in abdominal part, intestinal wall is congested, and enteral inflation is without food Thing, many mucus.Gill filament congestion or severe anemia etc..This disease is the most popular will be difficult to control to, and sickness rate is up to 100%, death Rate village may be up to 95%～100%.
The cause of disease of Carassius auratus burst hemorrhagic disease has Aeromonas hydrophila, Aeromonas sobria, vibrio fluvialis etc..Want at sick initial phase To water disinfection, first use three mixture (metrifonate 0.5mg/L, copper sulfate 1mg/L, ferrous sulfate 0.5mg/L), After 24h, sodium dichloro cyanurate of splashing (0.7-1mg/L), meanwhile, and the pharmaceutical chemistry containing norfloxacin of throwing something and feeding, continuous 3-5 My god.Wherein, norfloxacin is third generation quinolones broad-spectrum antiseptic antibiotic, is mainly used in the Gram-negative bacteria infections of various sensitivity Property treatment.This product can hinder the effect of the DNA helicase of malignant bacteria in digestive tract, hinders bacterium DNA replication, to antibacterial There is inhibitory action, be treatment enteritis and dysentery and the common medicine of urinary system infection.This Therapeutic Method is to the Carassius auratus burst hemorrhagic disease initial stage The treatment rate of sick fish about 70%.
Summary of the invention
It is an object of the invention to provide a kind of compositions treating Carassius auratus burst hemorrhagic disease, Carassius auratus burst is gone out by said composition The treatment rate of the sick fish at disorders of blood initial stage reaches more than 85%.
For reaching above-mentioned purpose, the base case of the present invention is: a kind of compositions treating Carassius auratus burst hemorrhagic disease, according to matter Amount number meter, including rice 11-16 part, little Herba Portulacae 9-15 part, Radix et rhizoma thalictri delavayi 5-7 part.
Rice has effect of antiinflammatory, sterilization.Little Herba Portulacae has effect of dysentery relieving sterilization；Cure mainly dysentery, enteritis, suffer from diarrhoea, Humid jaundice, impetigo, chronic ulcer of lower extremity.The root of Radix et rhizoma thalictri delavayi, for Rhizoma Coptidis use, has a bactericidal antiphlogistic, diaphoresis, Repercussive, dissipates poison, dissipates effect of gas；Control gastrointestinal heat symptom-complex, bloody dysentery.
The program have the beneficial effect that one be treatment Carassius auratus enteritis disease remarkably productive, cure rate reaches more than 85%；Two is choosing Treat enteritis disease with Chinese herbal medicine, while regulation fish internal milieu balance, increase fish body immunity, improve Carassius auratus and resist it The ability of his disease.
Prioritization scheme one: the optimization as to base case: according to mass fraction meter, also includes Folium Isatidis 9-15 gram, Radix Arnebiae (Radix Lithospermi) 9-15 gram, Herba Patriniae 9-15 gram, Semen Ziziphi Spinosae 6-10 gram.
Folium Isatidis has heat-clearing and toxic substances removing, effect of blood cooling and ecchymoses removing；Join the army for pathogenic warmth, unconsciousness due to high fever, a speckle dermexanthesis, jaundice, Hematodiarrhoea, mumps, sore throat, erysipelas, carbuncle.The effects such as Radix Arnebiae (Radix Lithospermi) has clearing away heat and cooling blood, invigorates blood circulation, removing toxic substances rash；For treating blood Pyretic toxicity is contained, macule purple is black, measles without adequate eruption.Herba Patriniae is conventional heat and toxic materials clearing away medicine, has heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood stasis dispelling Effect of pain relieving；For controlling gastric acid, hepatic cholagogic, antitumor, antibacterial, antiviral, the work for the treatment of chronic ulcerative colitis With.Semen Ziziphi Spinosae has tonifying liver, mind calming, arresting sweating, the effect promoted the production of body fluid.The beneficial effect of this programme, in addition to treatment sterilization, also has There is effect of heat clearing away, removing toxic substances, damp eliminating；Controlling retention of damp-heat in the interior, Shi Re Bing Pian is fought knot, stops up stagnant skin.
Prioritization scheme two: the optimization as to prioritization scheme one: also include Herba violae patrinii 8-11 part, Caulis et Folium Campsis 7-10 part.
Herba violae patrinii has heat-clearing and toxic substances removing, dissipating blood stasis blood, effect that sterilization is swollen；Control acute appendicitis, furuncle, red and swollen sore, jaundice, stranguria with turbid discharge, Mesh also gives birth to nebula.Caulis et Folium Campsis has removing heat from blood, effect of dissipating blood stasis；Control blood hot air wind producing, itching over the body, rubella, the aching and limp numbness of trick, pharynx Larynx swells and ache.This programme, in addition to sterilization, heat clearing away, removing toxic substances, damp eliminating, also has dissipating blood stasis blood, swollen effect of sterilizing.
Prioritization scheme three: the optimization as to prioritization scheme two: according to mass fraction meter, also includes Herba Leibnitziae 7-9 part, Radix osteomelis schwerinais 6-9 part.
Herba Leibnitziae has clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, cough-relieving, effect of hemostasis；For enteritis, dysentery, urinary tract infection；Outward With controlling carbuncle furuncle and phyma poison, sore, burn and scald, traumatic hemorrhage.Radix osteomelis schwerinais has heat-clearing and toxic substances removing, astringing to arrest diarrhea, effect of wind-damp dispelling； Cure mainly pharyngolaryngitis, parotitis, dysentery, enteritis, diarrhoea, rheumatic numbness, arthralgia, edema；Ulcerative carbuncle is controlled in external, unknown Toxic swelling, traumatic hemorrhage.The two taste Chinese medicine primary efficacy that this programme adds are treatment enteritis.Owing to causing Carassius auratus burst hemorrhagic disease One of pathogen Aeromonas hydrophila, be also the Main Pathogenic Bacteria causing Carassius auratus enteritis disease, so having infected Aeromonas hydrophila Carassius auratus easily suffer from enteritis disease, two kinds of disease superpositions have more increased the weight of the mortality rate of Carassius auratus.Add Herba Leibnitziae and on the one hand Radix osteomelis schwerinais alleviates Abdominal symptoms after Carassius auratus burst hemorrhagic disease；On the other hand can prevent and treat Carassius auratus Secondary cases enteritis disease, thus reduce dead Die rate.
Detailed description of the invention
Below by detailed description of the invention, the present invention is further detailed explanation:
Setup Experiments blank group, matched group, experiment A group, experiment B group, experiment C group, experiment D group, experiment E group, reality Testing F group, experiment G group, experiment H group, each group with an independent culturing pool.300 tails suffered from explosive hemorrhagic disease (body surface, each fin base portion, eye socket etc. are hemorrhage, and anus is red and swollen, and abdominal cavity is micro-hydrops, and body surface respective regions has slight perpendicular for sick fish Squama) all assign in ten groups at random, often organize 30 tails.
Each group feed formula is identical: according to mass fraction meter, fish flour 10 parts, wheat flour 15 parts, bean cake 25 parts, bone meal 5 parts, Fructus Cucurbitae moschatae powder 14 parts.
Outside divided by lower process difference, remaining condition is the most identical:
Blank group: feedstuff of throwing something and feeding, but not treated with medicaments.
Matched group: first use three mixture (metrifonate 0.5mg/L, copper sulfate 1mg/L, ferrous sulfate 0.5mg/L) and spray complete Pond, after 24h, sodium dichloro cyanurate of splashing (0.7-1mg/L), meanwhile, the feedstuff mixed with norfloxacin of throwing something and feeding.With Amount is every 100kg fish, medication every day 2-5g；Feed 5 days continuously.
Experiment A group: use compositions, according to mass fraction meter, including rice 12.5 parts, little Herba Portulacae 9 parts, Pian Chi Tang Pine mushroom root 6 parts.
Experiment B group: use compositions, according to mass fraction meter, including rice 11 parts, little Herba Portulacae 15 parts, Pian Chi Tang Pine mushroom root 5 parts.
Experiment C group: use compositions, according to mass fraction meter, including rice 16 parts, little Herba Portulacae 10 parts, Pian Chi Tang Pine mushroom root 7 parts, Folium Isatidis 9 grams, Radix Arnebiae (Radix Lithospermi) 9 grams, Herba Patriniae 9 grams, Semen Ziziphi Spinosae 6 grams.
Experiment D group: use compositions, according to mass fraction meter, including rice 12 parts, little Herba Portulacae 14 parts, Pian Chi Tang Pine mushroom root 5.3 parts, Folium Isatidis 15 grams, Radix Arnebiae (Radix Lithospermi) 15 grams, Herba Patriniae 15 grams, Semen Ziziphi Spinosae 10 grams.
Experiment E group: use compositions, according to mass fraction meter, including rice 15 parts, little Herba Portulacae 11 parts, Pian Chi Tang Pine mushroom root 6.5 parts, Folium Isatidis 10 grams, Radix Arnebiae (Radix Lithospermi) 10 grams, Herba Patriniae 10 grams, Semen Ziziphi Spinosae 7 grams, Herba violae patrinii 8 parts, Radix campsis stem 10 parts of leaf.
Experiment F group: use compositions, according to mass fraction meter, including rice 13 parts, little Herba Portulacae 13 parts, Pian Chi Tang Pine mushroom root 5.1 parts, Folium Isatidis 11 grams, Radix Arnebiae (Radix Lithospermi) 11 grams, Herba Patriniae 11 grams, Semen Ziziphi Spinosae 8 grams, Herba violae patrinii 11 parts, Radix campsis stem 7 parts of leaf.
Experiment G group: use compositions, according to mass fraction meter, including rice 14 parts, little Herba Portulacae 12 parts, Pian Chi Tang Pine mushroom root 6.8 parts, Folium Isatidis 13 grams, Radix Arnebiae (Radix Lithospermi) 13 grams, Herba Patriniae 13 grams, Semen Ziziphi Spinosae 9 grams, Herba violae patrinii 10 parts, Radix campsis Stem and leaf 8 parts, Herba Leibnitziae 7 parts, Radix osteomelis schwerinais 9 parts.
Experiment H group: use compositions, according to mass fraction meter, including rice 13.6 parts, little Herba Portulacae 10.6 parts, partially Wing Thalictrum aquilegifolium L. var. sibiricum Regel root 5.7 parts, Folium Isatidis 12 grams, Radix Arnebiae (Radix Lithospermi) 12 grams, Herba Patriniae 12 grams, Semen Ziziphi Spinosae 7.5 grams, Herba violae patrinii 9 parts, Caulis et Folium Campsis 9 parts, Herba Leibnitziae 9 parts, Radix osteomelis schwerinais 6 parts.
Wherein, experiment A group to experiment H group, decoct compositions according to the method for decocting herb, obtain medicinal liquid and medicinal residues；By medicinal liquid According to 0.5L/m3Consumption splash full pond, powder beaten by medicinal residues, medicinal residues powder and feedstuff is thrown something and fed Carassius auratus according to the ratio of 1:9, every day 1 Secondary, continuous 5 days.
After 5 days, experimental result is as follows:
Blank group Matched group Experiment A group Experiment B group Experiment C group Experiment D group Experiment E group Experiment F group Experiment G group Experiment H group
Cure (tail) 0 22 26 27 29 28 29 28 29 30
Take a turn for the better (tail) 0 7 2 2 0 1 1 2 1 0
Dead (tail) 29 3 2 1 1 1 0 0 0 0
Result is added up:
Blank group: dead 29 tail, other 1 shape of tail state is very poor, tends to disease and dies；Mortality rate 96.7%.
Matched group: cure rate 73.3%, improvement rate 23.3%, mortality rate 10.0%.
Experiment A group: cure rate 86.7%, improvement rate 6.7%, mortality rate 6.7%.
Experiment B group: cure rate 90.0%, improvement rate 6.7%, mortality rate 3.3%.
Experiment C group: cure rate 96.7%, improvement rate 0%, mortality rate 3.3%.
Experiment D group: cure rate 93.3%, improvement rate 3.3%, mortality rate 3.3%.
Experiment E group: cure rate 96.7%, improvement rate 3.3%, mortality rate 0.
Experiment F group: cure rate 93.3%, improvement rate 6.7%, mortality rate 0.
Experiment G group: cure rate 96.7%, improvement rate 3.3%, mortality rate 0.
Experiment H group: cure rate 100.0%, improvement rate 0, mortality rate 0.
Interpretation of result: experiment A group and B group are to have employed the base case of the present invention, experiment C group is to use to experiment H group The preferred version of base case, the cure rate of these eight experimental grouies is all significantly better than using the matched group of conventional solution, extremely Rate of dying is significantly lower than matched group.As can be seen here, the present invention has certain controlling for the sick fish suffering from the Carassius auratus burst hemorrhagic disease initial stage Treatment effect, and compared to existing technology, there is prominent substantive distinguishing features and significantly progress.
Above-described is only embodiments of the invention, and in scheme, the known general knowledge such as using method and characteristic is too much retouched at this State.It should be pointed out that, for a person skilled in the art, under the premise of not departing from the present invention, it is also possible to make some changing Entering, these also should be considered as protection scope of the present invention, and these are all without affecting effect and the practical applicability that the present invention implements. The protection domain that this application claims should be as the criterion with the content of its claim, and the detailed description of the invention in description etc. is recorded permissible For explaining the content of claim.

Claims (4)

1. the compositions treating Carassius auratus burst hemorrhagic disease, it is characterised in that: according to mass fraction meter, including rice 11-16 Part, little Herba Portulacae 9-15 part, Radix et rhizoma thalictri delavayi 5-7 part.
A kind of compositions treating Carassius auratus burst hemorrhagic disease the most according to claim 1, it is characterised in that: according to mass parts Number meter, also includes Folium Isatidis 9-15 gram, Radix Arnebiae (Radix Lithospermi) 9-15 gram, Herba Patriniae 9-15 gram, Semen Ziziphi Spinosae 6-10 gram.
A kind of compositions treating Carassius auratus burst hemorrhagic disease the most according to claim 2, it is characterised in that: according to mass parts Number meter, also includes Herba violae patrinii 8-11 part, Caulis et Folium Campsis 7-10 part.
A kind of compositions treating Carassius auratus burst hemorrhagic disease the most according to claim 3, it is characterised in that: according to mass parts Number meter, also includes Herba Leibnitziae 7-9 part, Radix osteomelis schwerinais 6-9 part.
CN201610339073.2A 2016-05-19 2016-05-19 Composition for treating fulminant hemorrhagic disease of crucian carps Pending CN105816538A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1091969A (en) * 1993-03-10 1994-09-14 黄永培 Compound drug for curing fish diseases
CN1099648A (en) * 1994-05-27 1995-03-08 齐宝山 Traditional Chinese medicine for curing bleeding disease and preparing method
CN1102333A (en) * 1993-11-04 1995-05-10 张素芳 Medicine for fish
CN102861162A (en) * 2012-10-18 2013-01-09 中国水产科学研究院长江水产研究所 Antiviral complex traditional Chinese medicine and preparation method and application thereof
CN105194361A (en) * 2014-06-30 2015-12-30 天津法莫西医药科技有限公司 Traditional Chinese medicine composition for preventing and treating hemorrhagic disease of aquatic animals and preparation method thereof
CN105193980A (en) * 2014-06-30 2015-12-30 天津法莫西医药科技有限公司 Traditional Chinese medicine composition for preventing and treating hemorrhagic disease of aquatic animals
CN105341528A (en) * 2015-11-20 2016-02-24 衡阳市富矿饲料添加剂有限公司 Chinese herbal medicinal feed additive for controlling hemorrhagic disease of grass carp, and preparation method thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1091969A (en) * 1993-03-10 1994-09-14 黄永培 Compound drug for curing fish diseases
CN1102333A (en) * 1993-11-04 1995-05-10 张素芳 Medicine for fish
CN1099648A (en) * 1994-05-27 1995-03-08 齐宝山 Traditional Chinese medicine for curing bleeding disease and preparing method
CN102861162A (en) * 2012-10-18 2013-01-09 中国水产科学研究院长江水产研究所 Antiviral complex traditional Chinese medicine and preparation method and application thereof
CN105194361A (en) * 2014-06-30 2015-12-30 天津法莫西医药科技有限公司 Traditional Chinese medicine composition for preventing and treating hemorrhagic disease of aquatic animals and preparation method thereof
CN105193980A (en) * 2014-06-30 2015-12-30 天津法莫西医药科技有限公司 Traditional Chinese medicine composition for preventing and treating hemorrhagic disease of aquatic animals
CN105341528A (en) * 2015-11-20 2016-02-24 衡阳市富矿饲料添加剂有限公司 Chinese herbal medicinal feed additive for controlling hemorrhagic disease of grass carp, and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
姬广闻、雷庆铎: "《新编鱼病综合防治手册》", 30 April 2002, 郑州：中原农民出版社 *

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