CN103211946B - Traditional Chinese medicine for treating gastric ulcer and duodenal ulcer - Google Patents
Traditional Chinese medicine for treating gastric ulcer and duodenal ulcer Download PDFInfo
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- CN103211946B CN103211946B CN201310163515.9A CN201310163515A CN103211946B CN 103211946 B CN103211946 B CN 103211946B CN 201310163515 A CN201310163515 A CN 201310163515A CN 103211946 B CN103211946 B CN 103211946B
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Abstract
The invention relates to a traditional Chinese medicine for treating gastric ulcer and duodenal ulcer. Specific to causes of the gastric ulcers, the natural herbal medicines which have the advantages of treating both symptoms and root causes as well as both deficiency and excess, contracting within dissipation, relieving pain and converging acid, and clearing away helicobator pylori are screened out and prepared into the traditional Chinese medicine in certain weight proportioning according to the prescription of traditional Chinese medicine theory in combination of clinical practice experience based on the principle of combination of disease differentiation and syndrome differentiation of the traditional Chinese medicine for treating gastric ulcer and duodenal ulcer. The traditional Chinese medicine is a traditional Chinese medicine composition which has an obvious curative effect and very little toxic and side effects and is used for treating gastric ulcer and duodenal ulcer.
Description
Technical field
The present invention relates to Chinese medicine composition, particularly a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer.
Background technology
Gastric ulcer and duodenal ulcer are a kind of multi-factor diseases, the cause of disease is complicated, completely unclear so far, the clearer and more definite cause of disease is helicobacter pylori infections, take non-steroid antiinflammatory drug, gastroxia and heredodiathesis, stress with the composite factor such as psychological factor, smoking caused by.Common clinical manifestation has the stomachache being confined to epigastrium, how to occur half an hour after the meal, continue 1-2 hour, fade away, also often have other gastrointestinal symptoms concurrently, as belch, acid regurgitation, heartburn, Nausea and vomiting etc., how slow onset is, and the course of disease reaches several years or many decades, in periodical attack, having a strong impact on Health and Living, can there is canceration in multiple epimegetic ulcer.In recent years clinical onset rate has the trend constantly risen.
At present, the duodenal medicine of domestic and international treatment harmonization of the stomach is a lot, as: magnalium gel, SIDASHU etc., these medicines can only mitigate the disease or for clinical a certain symptom treatment, often do not reach the effect of healing, a lot of Western medicine preparation inevitably has the obvious adverse reaction such as erythra, diarrhoea, hepatic injury in this kind of disease for the treatment of.In recent years someone work out control stomach Chinese medicine as Patent Office of the People's Republic of China discloses a kind of medicine for the treatment of stomach biliary diseases, publication number CN1539436A, has certain curative effect to ulcer, but its composition is single, prevention ulcer recurrence in have much room for improvement.
Summary of the invention
The object of the present invention is to provide the Chinese medicine of a kind for the treatment of gastric ulcer evident in efficacy and duodenal ulcer.
The object of the invention is to be realized by following approach: a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer, this Chinese medicine is made up of following component by weight percentage: Radix Toddaliae Asiaticae 4 ~ 20%, Rhizoma Corydalis 5 ~ 25%, Rhizoma Cyperi 5 ~ 25%, Endoconcha Sepiae 5 ~ 18%, Radix Notoginseng 4 ~ 20%, Cortex Ilicis Rotundae 5 ~ 18%, Fructus Zanthoxyli Plansipini 4 ~ 20%, wormwood 2 ~ 15%, Herba polygoni hydropiperis 2 ~ 15%, Concha Arcae 2 ~ 15%.
Preferred as this programme, this Chinese medicine is made up of following component by weight percentage: Radix Toddaliae Asiaticae 8%, Rhizoma Corydalis 16%, Rhizoma Cyperi 16%, Endoconcha Sepiae 11%, Radix Notoginseng 8%, Cortex Ilicis Rotundae 11%, Fructus Zanthoxyli Plansipini 8%, wormwood 5%, Herba polygoni hydropiperis 5%, Concha Arcae 5%.
Further, described Rhizoma Corydalis is vinegar system.
Further, described Rhizoma Cyperi is vinegar system.
Further, described Concha Arcae is calcine.
Further, described Endoconcha Sepiae is Testa Tritici parch.
Pharmacological property:
Pungent, the micro-hardship of Radix Toddaliae Asiaticae, temperature.Function cures mainly dissipating blood stasis hemostasis, expelling wind and removing dampness, subduing swelling and detoxicating.Be used for the treatment of rheumatalgia, stomachache, traumatic injury, spit blood, epistaxis, sub-official is hemorrhage, and knife injury is hemorrhage, amenorrhea, dysmenorrhea, intercostal neuralgia, furuncle toxic swelling.
Rhizoma Corydalis acrid in the mouth, bitter, temperature, function cures mainly: invigorate blood circulation, promoting the circulation of QI, pain relieving.Pain for stagnation of QI-blood is demonstrate,proved.The breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Rhizoma Cyperi (processed) acrid in the mouth, micro-hardship, sweet, property is put down.Effect: depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving.Cure mainly irritability stasis, hypochondriac pain uncomfortable in chest, gastropathy, stomachache; And menoxenia, the diseases such as dysmenorrhea.Endoconcha Sepiae property becomes, tepor effect: dehumidifying, antacid, hemostasis, sore.Treat for stomachache acid regurgitation, tells, epistaxis, hematemesis.Have blood in stool, bleeding not during menses, amenorrhea due to blood depletion, stomachache lump in the abdomen, intermittent fever of deficiency type dysentery, the rotten skin ulcer of the erosion of the vulva.Astringing to arrest bleeding, relieving leukorrhea by astringents, for acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge; Peptic Ulcers.External treatment bleeding due to trauma, the many pus of skin ulcer.
Radix Notoginseng nature and flavor: sweet in the mouth; Micro-hardship; Warm in nature.Function: hemostasis; Loose blood; Analgesic therapy.Cure mainly: fall and flutter congestive edema, thoracic obstruction angor, lump in the abdomen; Blood stasis amenorrhea; Dysmenorrhea; Puerperal, stasis of blood the moon was suffered from abdominal pain; Sore, carbuncle and painful swelling.
Cortex Ilicis Rotundae is cold in nature, bitter in the mouth effect: heat-clearing and toxic substances removing; Dampness removing; Pain relieving.For cold, fever; Laryngopharynx swelling and pain; Stomachache; Administration's diarrhea due to damp pathogen rushes down; Jaundice; Dysentery; Traumatic injury; Rheumatic arthralgia; Eczema; Furuncle.[Cortex Ilicis Rotundae bark is containing chemical composition flavonoid glycoside, phenols, tannin, Triterpene Glycosides isolate rotundicacid, 3-acetic acid oleanolic acid, stearic acid, sinapyladehyde, syringic aldehyde sinapyladehyde glycoside, Syringin, Folium Ilicis macrocarpae glycoside, β-Amyrin, cupreols etc., can suppress and remove helicobacter pylori.Make injection for clinical infection and pain relieving.
Bitter, pungent, the warm function of Fructus Zanthoxyli Plansipini nature and flavor: this product is fragrant stomach invigorating, warming middle-JIAO is regulated the flow of vital energy, expelling wind and removing dampness, wind dispelling parasite killing is micro-with narcoticness.Cure mainly stomach abdomen cold type of pain, gastrointestinal dysfunction, anemofrigid-damp arthralgia, abnormal rising of lung-QI, extremity severe and migratory arthralgia pain.
Wormwood bitter in the mouth, pungent, property are wet has invigorating the spleen to clear away damp pathogen, therapeutic method to keep the adverse QI flowing downwards dredging collateral, nourishing the liver stomach invigorating, malaria of relieving summer heat are antibacterial, parasiticide, solution thermal detoxification, function, Hunan is among the people makes artemisia-glutinous rice cake with wormwood and glutinous rice flour for raw material and eats, and has very large benefit to health.
Herba polygoni hydropiperis is pungent, temperature.Function cures mainly: reducing swelling and alleviating pain.Control abscess, dysentery is suffered from abdominal pain.Current clinical medicine research shows, Herba polygoni hydropiperis has the effect such as antibacterial, antiviral, antiinflammatory, antioxidation, hemostasis, antitumor, analgesia, and its effective ingredient is total flavones and terpene substances is main active substance, significantly can kill helicobacter pylori.
Concha Arcae (forging) nature and flavor become, flat.Function with cure mainly expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.For the long-pending knot of pertinacious phlegm, thickness difficulty is coughed up, goiter, scrofula, abdominal mass mass in the abdomen, stomachache pantothenic acid
A kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer of the present invention, from pain relieving, antacid is started with for the treatment of pain with distension primary symptom.Removing helicobacter pylori is fundamental policy, with Radix Toddaliae Asiaticae eliminating stasis to stop pain, Cortex Ilicis Rotundae containing syringoside anti-inflammatory and analgesic effect, Endoconcha Sepiae, Concha Arcae (forging) antacid sore, astringing to arrest bleeding, for principal agent, with Rhizoma Corydalis, Rhizoma Cyperi regulating QI to relieve pain, with Radix Notoginseng blood-activating analgetic, hemostasia and promoting granulation Fructus Zanthoxyli Plansipini adjusts stomach activating the spleen, wormwood invigorating the spleen to clear away damp pathogen, stomach reinforcing nourishing the stomach, for accessory drugs, close with Herba polygoni hydropiperis, remove helicobacter pylori, Cortex Ilicis Rotundae antiinflammatory sterilizes, mutual reinforcement between both clinical practice for many years proves and be used in and dispel the cause of disease and stop the effect that Recurrence can better play Synergistic, for clinical application provides a kind of selection newly.Be prevent ulcer recurrence, for a kind of approach of etiological treatment, there is advantages such as in addition having no side effect, expense is lower.Use the party to treat 89 routine gastric ulcers and duodenal ulcer patients, the ratio taking rear therapeutic effect is more than 90 percent, and cure rate is more than 78 percent.
Detailed description of the invention
A kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer of the present invention, this Chinese medicine is made up of following component by weight percentage: Radix Toddaliae Asiaticae 4 ~ 20%, Rhizoma Corydalis 5 ~ 25%, Rhizoma Cyperi 5 ~ 25%, Endoconcha Sepiae 5 ~ 18%, Radix Notoginseng 4 ~ 20%, Cortex Ilicis Rotundae 5 ~ 18%, Fructus Zanthoxyli Plansipini 4 ~ 20%, wormwood 2 ~ 15%, Herba polygoni hydropiperis 2 ~ 15%, Concha Arcae 2 ~ 15%.As the optimal proportion of this component, this Chinese medicine is made up of following component by weight percentage: Radix Toddaliae Asiaticae 8%, Rhizoma Corydalis 16%, Rhizoma Cyperi 16%, Endoconcha Sepiae 11%, Radix Notoginseng 8%, Cortex Ilicis Rotundae 11%, Fructus Zanthoxyli Plansipini 8%, wormwood 5%, Herba polygoni hydropiperis 5%, Concha Arcae 5%.Described Rhizoma Corydalis, Rhizoma Cyperi are vinegar system, and Concha Arcae is calcine, and Endoconcha Sepiae is Testa Tritici parch.
A kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer of the present invention is powder, gets said components Chinese crude drug in proportion, by Chinese crude drug concocted specification clean dry after, be ground into fine powder cross 120 mesh sieves after and get final product.Wherein Rhizoma Corydalis, Rhizoma Cyperi vinegar system, Endoconcha Sepiae must be fried by Testa Tritici.Usage and dosage: dosage one of the present invention course for the treatment of is quality is 180 grams, takes for 15 days, in after meal early, before supper, respectively takes four grams before sleeping.Warm water takes.
A kind of clinical observation on the therapeutic effect experiment for the treatment of the Chinese medicine of gastric ulcer and duodenal ulcer of the present invention:
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 52 routine patients altogether, wherein man 39 example,
Female 13 example; The oldest person 77 years old, age reckling 21 years old.
Two, Therapeutic Method:
Usage and dosage: adopt medicament prepared by the embodiment of the present invention, its usage is as follows with consumption: the dose one weight course for the treatment of is 180 grams, in morning after meal, before supper, before sleeping, respectively take four grams.Warm water takes.The course for the treatment of: 15 days be a course for the treatment of, treat 6 ~ 8 courses for the treatment of altogether.
Three, the standard of curative effect evaluation
Cure: sign and symptom are improved completely, diet digestive is normal, in high spirits.
Effective: sign and symptom are improved completely, and diet digestive is normal, in high spirits.
Effective: sign and symptom change, random thoughts are slightly uncomfortable, but can accept.
Invalid: sign is without change, and symptom is as front.
Four, model case:
1, certain is revived, man, 43 years old, workman.
During the teen age, often stomachache, was often easy to outbreak in spring and autumn afterwards.Suddenly to have a stomachache before March pantothenic acid, then vomit
Coffee-like liquid is a lot of, and black stool, moves in county hospital at once through looking into as " gastric ulcer is also hemorrhage ", and after being in hospital, blood only.Now demonstrate,prove: often gastral cavilty falling inflation sense of heaviness, belch, distension dull pain after drinking water fruit then eats immediately, bitter in mouth, the clear water mucus that must spue after each feed flatly.Be hard and dry two or three once, darkish complexion sometimes.Food is swollen afterwards and dare not take food more.The thin Huang of shape, lip is dark red.The micro-cunning of stringy pulse, red tongue with thin fur is white.
Take Chinese medicine composition of the present invention 7, gastral cavilty falling inflation sense of heaviness slightly subtracts, and defecate still constipated difficulty row.Following the service Chinese medicine composition of the present invention 15 days, gastral cavilty falling inflation sense of heaviness subtracts greatly, defecates smooth and easy, and day 1 time, color is normal.Following the service Chinese medicine composition of the present invention 1 month, patient is well conscious, and appetite is gradually normal, and complexion turns profit, and lip is light.Take again more than Chinese medicine composition of the present invention April, recovery from illness, resumes work, recently looks into through gastroscope: ulcer disappears completely.
2, Zhang, man, 33 years old, workman.
Patient's readme discontinuity gastralgia more than 6 years, alternately takes that compound stomach is healthy and free from worry, the Western medicine such as ranitidine, Lignum Aquilariae Resinatum show money or valuables one carries unintentionally, bismuth aluminate compound for a long time, heavy time light during the state of an illness.Often because feelings will is not smooth, eating and drinking without temperance, especially drinks or the pungent then aggravation of surfeit.Point out through gastroscopy: 1. chronic superficial gastritis (congested |, rotten to the corn) 2. multiple gastric ulcer (A2).The existing scorching hot distending pain of gastral cavilty of HP (++), sore spot tenderness, connects and two sides of body, belch, dry mouth with bitter taste, susceptible to lose temper due to restlessness, noisy pantothenic acid, dry stool darkish complexion, dimly red tongue, yellow and thin fur, stringy and thready pulse sometimes.
Take Chinese medicine composition of the present invention 15, burning pain in the epigastrium, dry mouth with bitter taste, belch, susceptible to lose temper due to restlessness symptom subtract greatly, noisy pantothenic acid, dry stool darkish complexion transference cure.Following the service Chinese medicine composition of the present invention 15 days, all diseases disappear substantially, and spirit, diet are all good, and two is just normal.Take again more than Chinese medicine composition of the present invention March, without special malaise symptoms, point out through gastroscopy: no abnormality seen, HP (-)
Disease obtains recovery from illness.
3, patient is tired from being set forth in cause overwork in 4 years, eating and drinking without temperance in addition, and hungry full inappropriate, the product that eating is raw and cold, greasy, pungent again, cause gastralgia, and health is become thin gradually.Though long-term taking relies on the multiple Chinese and western drugs treatment such as ratio, bismuth aluminate compound, ranitidine, omeprazole, spleen-strengthening bolus, stomach function regulating whole intestinal ball, heavy time light during the state of an illness, recurrent exerbation, does not cure eventually.Causing again stomachache before 1 week to increase the weight of because drinking ice beer, pointing out through gastroscopy: 1. superficial gastritis 2. duodenal ulcer .HP (+).When examining, disease is seen: gastral cavilty twinge, and sore spot is fixing not to be moved, abdominal distention, poor appetite, belch, and body is tired weak, and large loose stool is thin, day row 3 ~ 4 times, pale tongue is dark, and greatly fat, while see ecchymosis, tongue is greasy in vain, deep and hesitant pulse.
Take Chinese medicine composition of the present invention 20, stomachache is not done, and abdominal distention, belch symptom subtract greatly, health comparatively before strong, receive food comparatively before increase, still large loose stool is thin, day row 2 ~ 3 times.Following the service Chinese medicine composition of the present invention 20 days, all diseases disappear, and spirit, muscle power, diet, stool are all normal, and complexion is tending towards ruddy, and body weight is comparatively front to be increased, but raw food of taking food whenever, pungent product, namely feel in stomach and having a dull ache.Take again Chinese medicine composition of the present invention 2 months, spirit, diet are all good, without special discomfort, through check gastroscope: ulcer healing, HP (-) disease obtains recovery from illness, follows up a case by regular visits to after 1 year, does not feel special discomfort.
Five, therapeutic outcome:
In accepted for medical treatment 89 routine cases, through treatment in 2 to 4 months, wherein cure 55 examples, effective 21 examples, effective 8 examples, invalid 5 examples, total effective rate reaches 94%.Result shows, Chinese medicine composition of the present invention has extremely significant curative effect to treatment gastric ulcer and duodenal ulcer patients.
Claims (1)
1. treat the Chinese medicine of gastric ulcer and duodenal ulcer for one kind, it is characterized in that: this Chinese medicine is made up of following component by weight percentage: Radix Toddaliae Asiaticae 4 ~ 20%, Rhizoma Corydalis 5 ~ 25%, Rhizoma Cyperi 5 ~ 25%, Endoconcha Sepiae 5 ~ 18%, Radix Notoginseng 4 ~ 20%, Cortex Ilicis Rotundae 5 ~ 18%, Fructus Zanthoxyli Plansipini 4 ~ 20%, wormwood 2 ~ 15%, Herba polygoni hydropiperis 2 ~ 15%, Concha Arcae 2 ~ 15%; Described Rhizoma Corydalis is vinegar system, and Rhizoma Cyperi is vinegar system, and Concha Arcae is calcine, and Endoconcha Sepiae is Testa Tritici parch.
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| CN201310163515.9A CN103211946B (en) | 2013-05-07 | 2013-05-07 | Traditional Chinese medicine for treating gastric ulcer and duodenal ulcer |
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| CN105878309A (en) * | 2016-05-31 | 2016-08-24 | 剑河县南明镇箭猪养殖专业合作社 | Traditional Chinese medicine formula for treating gastric ulcer |
| CN108992468A (en) * | 2017-06-06 | 2018-12-14 | 李俐 | Purposes of the pharmaceutical composition in the drug that preparation is used for anti-helicobacter pylori |
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| CN1132617C (en) * | 1998-10-08 | 2003-12-31 | 李培成 | Stomach-benefiting powder |
| CN101062349A (en) * | 2007-06-07 | 2007-10-31 | 巩振宏 | Chinese traditional medicine agent for treating gastralgia |
| CN101138616A (en) * | 2007-09-08 | 2008-03-12 | 门连社 | Prescription for treating tummy bug |
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