CN103211946A - Traditional Chinese medicine for treating gastric ulcer and duodenal ulcer - Google Patents
Traditional Chinese medicine for treating gastric ulcer and duodenal ulcer Download PDFInfo
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- CN103211946A CN103211946A CN2013101635159A CN201310163515A CN103211946A CN 103211946 A CN103211946 A CN 103211946A CN 2013101635159 A CN2013101635159 A CN 2013101635159A CN 201310163515 A CN201310163515 A CN 201310163515A CN 103211946 A CN103211946 A CN 103211946A
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Abstract
The invention relates to a traditional Chinese medicine for treating gastric ulcer and duodenal ulcer. Specific to causes of the gastric ulcers, the natural herbal medicines which have the advantages of treating both symptoms and root causes as well as both deficiency and excess, contracting within dissipation, relieving pain and converging acid, and clearing away helicobator pylori are screened out and prepared into the traditional Chinese medicine in certain weight proportioning according to the prescription of traditional Chinese medicine theory in combination of clinical practice experience based on the principle of combination of disease differentiation and syndrome differentiation of the traditional Chinese medicine for treating gastric ulcer and duodenal ulcer. The traditional Chinese medicine is a traditional Chinese medicine composition which has an obvious curative effect and very little toxic and side effects and is used for treating gastric ulcer and duodenal ulcer.
Description
Technical field
The present invention relates to Chinese medicine composition, particularly a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer.
Background technology
Gastric ulcer and duodenal ulcer are a kind of multi-factor diseases, cause of disease complexity, unclear fully so far, the clearer and more definite cause of disease is helicobacter pylori infections, take non-steroid antiinflammatory drug, gastroxia and heredodiathesis, stress with composite factors such as psychological factor, smoking due to.Common clinical manifestation has the stomachache of the epigastrium of being confined to, how to occur half an hour after the meal, continue 1-2 hour, fade away, also often have other gastrointestinal symptoms concurrently, as belch, acid regurgitation, heartburn, nauseating, vomiting etc., how slow onset is, and the course of disease reaches several years or many decades, is periodical attack, have a strong impact on Health and Living, canceration can take place in multiple epimegetic ulcer.In recent years the clinical onset rate has the trend of continuous rising.
At present, the duodenal medicine of treatment harmonization of the stomach is a lot of both at home and abroad, as: magnalium gel, SIDASHU etc., these medicines can only mitigate the disease or at clinical a certain symptom treatment, often do not reach the effect of healing, a lot of Western medicine preparations inevitably have obvious adverse reaction such as erythra, diarrhoea, hepatic injury in this class disease of treatment.In recent years the someone works out the Chinese medicine such as the Patent Office of the People's Republic of China that control stomach and discloses a kind of medicine for the treatment of the stomach biliary diseases, and publication number CN1539436A has certain curative effect to ulcer, but its composition is single, is having much room for improvement aspect the prevention ulcer recurrence.
Summary of the invention
The object of the present invention is to provide a kind of treatment gastric ulcer evident in efficacy and the Chinese medicine of duodenal ulcer.
The objective of the invention is to realize: a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer by following approach, this Chinese medicine is made of following component by weight percentage: Radix Toddaliae Asiaticae 4～20%, Rhizoma Corydalis 5～25%, Rhizoma Cyperi 5～25%, Endoconcha Sepiae 5～18%, Radix Notoginseng 4～20%, Cortex Ilicis Rotundae 5～18%, Fructus Zanthoxyli Plansipini 4～20%, wormwood 2～15%, Herba polygoni hydropiperis 2～15%, Concha Arcae 2～15%.
Preferred as this programme, this Chinese medicine is made of following component by weight percentage: Radix Toddaliae Asiaticae 8%, Rhizoma Corydalis 16%, Rhizoma Cyperi 16%, Endoconcha Sepiae 11%, Radix Notoginseng 8%, Cortex Ilicis Rotundae 11%, Fructus Zanthoxyli Plansipini 8%, wormwood 5%, Herba polygoni hydropiperis 5%, Concha Arcae 5%.
Further, described Rhizoma Corydalis is a vinegar system.
Further, described Rhizoma Cyperi is a vinegar system.
Further, described Concha Arcae is a calcine.
Further, described Endoconcha Sepiae is the Testa Tritici parch.
Pharmacological property:
Radix Toddaliae Asiaticae suffering, little hardship, temperature.Function cures mainly dissipating blood stasis hemostasis, expelling wind and removing dampness, subduing swelling and detoxicating.Be used for the treatment of rheumatalgia, stomachache, traumatic injury is spitted blood, epistaxis, sub-official is hemorrhage, and knife injury is hemorrhage, amenorrhea, dysmenorrhea, intercostal neuralgia, furuncle toxic swelling.
The Rhizoma Corydalis acrid in the mouth, hardship, temperature, function cures mainly: invigorate blood circulation promoting the circulation of QI, pain relieving.The card bitterly that is used for stagnation of QI-blood.The breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Rhizoma Cyperi (processed) acrid in the mouth, little hardship, sweet, property is flat.Effect: depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving.Cure mainly irritability stasis, hypochondriac pain uncomfortable in chest, gastropathy, stomachache; And menoxenia, diseases such as dysmenorrhea.Endoconcha Sepiae property one-tenth, the tepor effect: dehumidifying, antacid, skin ulcer is held back in hemostasis.The acid regurgitation that treats for stomachache is told, epistaxis, hematemesis.Have blood in stool, bleeding not during menses, amenorrhea due to blood depletion, the stomachache lump in the abdomen, the intermittent fever of deficiency type dysentery, skin ulcer is rotted in the erosion of the vulva.Astringing to arrest bleeding, relieving leukorrhea by astringents is used to the acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge; Peptic Ulcers.The external treatment bleeding due to trauma, the many pus of skin ulcer.
Radix Notoginseng nature and flavor: sweet in the mouth; Little hardship; Warm in nature.Function: hemostasis; Blood looses; Analgesic therapy.Cure mainly: fall and pounce on congestive edema, thoracic obstruction angor, lump in the abdomen; The blood stasis amenorrhea; Dysmenorrhea; The cloudy stomachache of the stasis of blood in puerperal; Sore, carbuncle and painful swelling.
Cortex Ilicis Rotundae is cold in nature, and the bitter in the mouth effect cures mainly: heat-clearing and toxic substances removing; Dampness removing; Pain relieving.Be used for cold, fever; Laryngopharynx swelling and pain; Stomachache; Administration's diarrhea due to damp pathogen rushes down; Jaundice; Dysentery; Traumatic injury; Rheumatic arthralgia; Eczema; Furuncle.[the Cortex Ilicis Rotundae bark contains chemical constituent flavonoid glycoside, phenols, tannin, Triterpene Glycosides and isolates rotundicacid, 3-acetic acid oleanolic acid, stearic acid, sinapyladehyde, syringic aldehyde sinapyladehyde glycoside, Syringin, the Folium Ilicis macrocarpae glycoside, β-Amyrin, cupreols etc. can suppress and remove helicobacter pylori.Make injection and be used for clinical infection and pain relieving.
Fructus Zanthoxyli Plansipini nature and flavor hardship, suffering, warm function: this product is that fragrance is good for the stomach, warming middle-JIAO is regulated the flow of vital energy, expelling wind and removing dampness, wind dispelling parasite killing, little narcoticness that has.Cure mainly stomach abdomen cold type of pain, gastrointestinal dysfunction, anemofrigid-damp arthralgia, abnormal rising of lung-QI, extremity severe and migratory arthralgia pain.
Wormwood bitter in the mouth, suffering, property be wet to have invigorating the spleen to clear away damp pathogen, a therapeutic method to keep the adverse QI flowing downwards collateral dredging, nourishing the liver is good for the stomach, relieves summer heat that malaria is antibiotic, parasiticide, separate thermal detoxification, function, the Hunan is among the people, and to be with wormwood and glutinous rice flour that raw material is made artemisia-glutinous rice cake edible, and health is had very big benefit.
The Herba polygoni hydropiperis suffering, temperature.Function cures mainly: reducing swelling and alleviating pain.Control abscess, dysentery stomachache.Current clinical medicine studies show that, effects such as that Herba polygoni hydropiperis has is antibiotic, antiviral, antiinflammatory, antioxidation, hemostasis, antitumor, analgesia, and its effective ingredient is that total flavones and terpene substances are main active substance, can significantly kill helicobacter pylori.
Concha Arcae (forging) nature and flavor become, and are flat.Function with cure mainly expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache.Be used for the long-pending knot of pertinacious phlegm, the thickness difficulty is coughed up, goiter, scrofula, abdominal mass mass in the abdomen, stomachache pantothenic acid
A kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer of the present invention, from pain relieving, antacid is treated at the pain with distension primary symptom and is started with.Remove the plan of helicobacter pylori for effecting a permanent cure, with the Radix Toddaliae Asiaticae eliminating stasis to stop pain, the Cortex Ilicis Rotundae that contains the syringoside anti-inflammatory and analgesic effect, Endoconcha Sepiae, skin ulcer is held back in Concha Arcae (forging) antacid, astringing to arrest bleeding, be principal agent, with Rhizoma Corydalis, the Rhizoma Cyperi regulating QI to relieve pain, with the Radix Notoginseng blood-activating analgetic, the hemostasia and promoting granulation Fructus Zanthoxyli Plansipini is transferred the stomach activating the spleen, the wormwood invigorating the spleen to clear away damp pathogen, the stomach reinforcing nourishing the stomach is accessory drugs, closes with Herba polygoni hydropiperis, remove helicobacter pylori, the sterilization of Cortex Ilicis Rotundae antiinflammatory, clinical practice for many years proves both mutual reinforcements between and is used in and dispels the cause of disease and stop the effect that the recurrence factor can better play Synergistic, for clinical application provides a kind of new selection.Be to prevent ulcer recurrence,, have advantage such as have no side effect, expense is lower in addition at a kind of approach of etiological treatment.Use this side that 89 routine gastric ulcers and duodenal ulcer patients are treated, the ratio of taking the back therapeutic effect is more than 90 percent, and cure rate is more than 78 percent.
The specific embodiment
A kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer of the present invention, this Chinese medicine is made of following component by weight percentage: Radix Toddaliae Asiaticae 4～20%, Rhizoma Corydalis 5～25%, Rhizoma Cyperi 5～25%, Endoconcha Sepiae 5～18%, Radix Notoginseng 4～20%, Cortex Ilicis Rotundae 5～18%, Fructus Zanthoxyli Plansipini 4～20%, wormwood 2～15%, Herba polygoni hydropiperis 2～15%, Concha Arcae 2～15%.As the optimal proportion of this component, this Chinese medicine is made of following component by weight percentage: Radix Toddaliae Asiaticae 8%, Rhizoma Corydalis 16%, Rhizoma Cyperi 16%, Endoconcha Sepiae 11%, Radix Notoginseng 8%, Cortex Ilicis Rotundae 11%, Fructus Zanthoxyli Plansipini 8%, wormwood 5%, Herba polygoni hydropiperis 5%, Concha Arcae 5%.Described Rhizoma Corydalis, Rhizoma Cyperi are vinegar system, and Concha Arcae is a calcine, and Endoconcha Sepiae is the Testa Tritici parch.
A kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer of the present invention is powder, gets the said components Chinese crude drug in proportion, by the Chinese crude drug concocted specification clean dry after, grind into fine powder and cross behind 120 mesh sieves promptly.Wherein Rhizoma Corydalis, Rhizoma Cyperi vinegar system, Endoconcha Sepiae must be fried by Testa Tritici.Usage and dosage: one course of treatment of dosage of the present invention is that quality is 180 grams, takes in 15 days, in after meal early, before the supper, respectively obeys four grams before sleeping.Warm water takes.
A kind of clinical observation on the therapeutic effect experiment for the treatment of the Chinese medicine of gastric ulcer and duodenal ulcer of the present invention:
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 52 routine patients altogether, wherein male 39 examples,
Woman's 13 examples; The oldest person 77 years old, age reckling 21 years old.
Two, Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: dose weight one course of treatment is 180 grams, in after meal early, before the supper, respectively obeys four grams before sleeping.Warm water takes.The course of treatment: 15 days is a course of treatment, treats 6～8 courses of treatment altogether.
Three, therapeutic evaluation standard
Cure: sign and symptom are improved fully, and diet digestion is normal, in high spirits.
Produce effects: sign and symptom are improved fully, and diet digestion is normal substantially, in high spirits.
Effectively: sign and symptom change, and random thoughts have discomfort slightly, but can accept.
Invalid: sign does not have change, symptom such as preceding.
Four, model case:
1, revives certain, man, 43 years old, workman.
Often stomachache whenever was easy to outbreak in spring and autumn afterwards during the teen age.Suddenly the pantothenic acid of having a stomachache before March, vomiting then
Coffee-like liquid is a lot of, and black stool is moved in county hospital at once and is " gastric ulcer is also hemorrhage " through looking into, and the bleeding from anus of being in hospital ends.Now demonstrate,prove: often gastral cavilty weighs down the sense of heaviness that expands, belch, and the drinking water fruit then eats back distension dull pain immediately, and is bitter in mouthful, the clear water mucus that must spue after each feed a bite.Be hard and dry two or three once, sometimes darkish complexion.Expand and dare not take food more in the food back.The thin Huang of shape, lip is dark red.The little cunning of stringy pulse, red tongue with thin fur is white.
Took Chinese medicine composition of the present invention 7, gastral cavilty weighs down the sense of heaviness that expands and slightly subtracts, and still constipated difficult row defecates.Continue and obeyed Chinese medicine composition of the present invention 15, gastral cavilty weighs down the sense of heaviness that expands and subtracts greatly, and it is smooth and easy to defecate, and day 1 time, color is normal.Continue and obeyed Chinese medicine composition of the present invention 1 month, the patient is conscious good, and appetite is gradually normal, and complexion is changeed profit, and lip is light.It is surplus April to obey Chinese medicine composition of the present invention again, and recovery from illness is resumed work, and looks into through gastroscope recently: the ulcer complete obiteration.
2, Zhang, man, 33 years old, workman.
Patient's readme discontinuity gastralgia 6 years is surplus, alternately takes Western medicine such as compound recipe WEIKANGNING, ranitidine, Lignum Aquilariae Resinatum show money or valuables one carries unintentionally, bismuth aluminate compound for a long time, and is heavy when light during the state of an illness.Every not smooth because of feelings will, eating and drinking without temperance is especially drunk or the pungent then state of an illness of surfeit increases the weight of.Point out through gastroscopy: 1. 2. multiple gastric ulcer (A2) of chronic superficial gastritis (hyperemia |, erosion).The existing scorching hot distending pain of gastral cavilty of HP (++), the sore spot tenderness connects and two sides of body sometimes, belch, dry mouth with bitter taste, susceptible to lose temper due to restlessness, noisy pantothenic acid, dry stool darkish complexion, dimly red tongue, yellow and thin fur, stringy and thready pulse.
Took Chinese medicine composition of the present invention 15, burning pain in the epigastrium, dry mouth with bitter taste, belch, susceptible to lose temper due to restlessness symptom subtract greatly, noisy pantothenic acid, dry stool darkish complexion transference cure.The clothes Chinese medicine composition of the present invention 15 days that continues, all diseases disappear substantially, and spirit, diet are all good, and two is just normal.It is surplus March to obey Chinese medicine composition of the present invention again, does not have special malaise symptoms, points out through gastroscopy: no abnormality seen, HP (-)
Disease obtains recovery from illness.
3, it is tired that the patient is set forth in cause overwork in 4 years certainly, and eating and drinking without temperance is hungry full inappropriate in addition, likes raw and cold, greasy, the pungent product of food again, causes gastralgia, and health is become thin gradually.Though take multiple Chinese and western drugses treatments such as the whole intestinal ball of support ratio, bismuth aluminate compound, ranitidine, omeprazole, spleen-strengthening bolus, stomach function regulating for a long time, heavy when light during the state of an illness, outbreak is repeatedly cured eventually.Caused stomachache and increase the weight of because of drinking ice beer again before 1 week, point out through gastroscopy: 1. superficial gastritis 2. duodenal ulcer .HP (+).Disease is seen when examining: the gastral cavilty twinge, and sore spot is fixing not to be moved, abdominal distention, poor appetite, belch, body is tired weak, and big loose stool is thin, day row 3～4 times, pale tongue is dark, and fat big, ecchymosis is seen on the limit, and tongue is greasy in vain, deep and hesitant pulse.
Took Chinese medicine composition of the present invention 20, stomachache is done, and abdominal distention, belch symptom subtract greatly, and health is more preceding strong, receives and eats more preceding increase, and still big loose stool is thin, day row 2～3 times.The clothes Chinese medicine composition of the present invention 20 days that continues, all diseases disappear, and spirit, muscle power, diet, stool are all normal, and it is ruddy that complexion is tending towards, and the more preceding increase of body weight, but raw and cold, the pungent product of taking food are whenever promptly felt in the stomach and being had a dull ache.Obeyed Chinese medicine composition of the present invention again 2 months, spirit, diet is all good, do not have special discomfort, and through the check gastroscope: ulcer healing, HP (-) disease obtains recovery from illness, follows up a case by regular visits to after 1 year, does not feel special discomfort.
Five, therapeutic outcome:
In the 89 routine cases of being accepted for medical treatment,, wherein cure 55 examples through treatment in 2 to 4 months, produce effects 21 examples, effective 8 examples, invalid 5 examples, total effective rate reaches 94%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment gastric ulcer and duodenal ulcer patients.
Claims (6)
1. Chinese medicine for the treatment of gastric ulcer and duodenal ulcer, it is characterized in that: this Chinese medicine is made of following component by weight percentage: Radix Toddaliae Asiaticae 4～20%, Rhizoma Corydalis 5～25%, Rhizoma Cyperi 5～25%, Endoconcha Sepiae 5～18%, Radix Notoginseng 4～20%, Cortex Ilicis Rotundae 5～18%, Fructus Zanthoxyli Plansipini 4～20%, wormwood 2～15%, Herba polygoni hydropiperis 2～15%, Concha Arcae 2～15%.
2. a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer as claimed in claim 1, it is characterized in that: this Chinese medicine is made of following component by weight percentage: Radix Toddaliae Asiaticae 8%, Rhizoma Corydalis 16%, Rhizoma Cyperi 16%, Endoconcha Sepiae 11%, Radix Notoginseng 8%, Cortex Ilicis Rotundae 11%, Fructus Zanthoxyli Plansipini 8%, wormwood 5%, Herba polygoni hydropiperis 5%, Concha Arcae 5%.
3. a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer as claimed in claim 1 or 2 is characterized in that: described Rhizoma Corydalis is a vinegar system.
4. a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer as claimed in claim 1 or 2 is characterized in that: described Rhizoma Cyperi is a vinegar system.
5. a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer as claimed in claim 1 or 2 is characterized in that: described Concha Arcae is a calcine.
6. a kind of Chinese medicine for the treatment of gastric ulcer and duodenal ulcer as claimed in claim 1 or 2 is characterized in that: described Endoconcha Sepiae is the Testa Tritici parch.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310163515.9A CN103211946B (en) | 2013-05-07 | 2013-05-07 | Traditional Chinese medicine for treating gastric ulcer and duodenal ulcer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310163515.9A CN103211946B (en) | 2013-05-07 | 2013-05-07 | Traditional Chinese medicine for treating gastric ulcer and duodenal ulcer |
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| CN103211946B CN103211946B (en) | 2015-05-06 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105878309A (en) * | 2016-05-31 | 2016-08-24 | 剑河县南明镇箭猪养殖专业合作社 | Traditional Chinese medicine formula for treating gastric ulcer |
| CN108992468A (en) * | 2017-06-06 | 2018-12-14 | 李俐 | Purposes of the pharmaceutical composition in the drug that preparation is used for anti-helicobacter pylori |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1223879A (en) * | 1998-10-08 | 1999-07-28 | 李培成 | Stomach-benefiting powder |
| CN101062349A (en) * | 2007-06-07 | 2007-10-31 | 巩振宏 | Chinese traditional medicine agent for treating gastralgia |
| CN101138616A (en) * | 2007-09-08 | 2008-03-12 | 门连社 | Prescription for treating tummy bug |
-
2013
- 2013-05-07 CN CN201310163515.9A patent/CN103211946B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1223879A (en) * | 1998-10-08 | 1999-07-28 | 李培成 | Stomach-benefiting powder |
| CN101062349A (en) * | 2007-06-07 | 2007-10-31 | 巩振宏 | Chinese traditional medicine agent for treating gastralgia |
| CN101138616A (en) * | 2007-09-08 | 2008-03-12 | 门连社 | Prescription for treating tummy bug |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105878309A (en) * | 2016-05-31 | 2016-08-24 | 剑河县南明镇箭猪养殖专业合作社 | Traditional Chinese medicine formula for treating gastric ulcer |
| CN108992468A (en) * | 2017-06-06 | 2018-12-14 | 李俐 | Purposes of the pharmaceutical composition in the drug that preparation is used for anti-helicobacter pylori |
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| Publication number | Publication date |
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| CN103211946B (en) | 2015-05-06 |
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