CN103961630A - Traditional Chinese medicine composition for treating stomach Qi deficiency - Google Patents

Traditional Chinese medicine composition for treating stomach Qi deficiency Download PDF

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Publication number
CN103961630A
CN103961630A CN201410233241.0A CN201410233241A CN103961630A CN 103961630 A CN103961630 A CN 103961630A CN 201410233241 A CN201410233241 A CN 201410233241A CN 103961630 A CN103961630 A CN 103961630A
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China
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parts
chinese medicine
stomach
traditional chinese
medicine composition
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CN201410233241.0A
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陈晓明
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BENGBU MINGRIXIN PHARMACEUTICAL Co Ltd
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BENGBU MINGRIXIN PHARMACEUTICAL Co Ltd
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Priority to CN201410233241.0A priority Critical patent/CN103961630A/en
Publication of CN103961630A publication Critical patent/CN103961630A/en
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Abstract

The invention provides a traditional Chinese medicine composition for treating stomach Qi deficiency. The traditional Chinese medicine composition is characterized by being prepared from the following traditional Chinese medicine raw materials according to a weight ratio: 5-15 parts of fructus gardeniae praeparata, 5-15 parts of rhizoma coptidis, 20-40 parts of dandelion, 5-15 parts of fructus aurantii preparata, 10-20 parts of white paeony root, 5-15 parts of radix bupleuri, 5-15 parts of honey-fried licorice root, 5-15 parts of concha arcae preparata and 5-15 parts of fructus amomi. The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition has a good treatment effect on symptoms such as swelling pain of stomach, poor appetite, lassitude, body fatigue and weakness caused by stomach qi deficiency and small toxic or side effects and is capable of consolidating basis and relatively low in treatment cost, and after the stomach Qi deficiency is healed, the relapse rate is low, and the like.

Description

A kind of Chinese medicine composition for the treatment of insufficiency of stomach-QI
Technical field:
The present invention relates to Chinese medicine technical field, particularly a kind of Chinese medicine composition for the treatment of insufficiency of stomach-QI.
Background technology:
Insufficiency of stomach-QI refers to being received of stomach and the digesting and absorbing the essence of foodstuff function weakness that disappears,, pain relieved by pressing swollen with vague epigastralgia or painful abdominal mass, the weak syndrome that lack of appetite etc. are main manifestations.Assertive evidence is many because of many eating and drinking without temperances, irregular diet, and overstrain, prolonged illness is lost and is supported, and the impacts of other Zang-Fu syndromes etc. damage due to gastric qi.At present, due to China's expanding economy, people more and more, due to the relation of work, causes that chronic dietary is unclean, diet is irregular, occurs the problems such as stomach discomfort, and people are alleviated sense of discomfort with stomach medicine mostly.But owing to curing the symptoms, not the disease, often long-term taking stomach medicine, thus cause the further infringement of stomach.
Summary of the invention:
The present invention is exactly in order to overcome deficiency of the prior art, provide a kind of cause for insufficiency of stomach-QI as stomach distending pain, be off one's feed, lassitude, it is good that the idle disease such as weak of body has therapeutic effect, vital base and primordial QI consolidating, and treatment cost is lower, and toxic and side effects is little, control the Chinese medicine composition that recurrence rate after healing is low.
The invention provides following technical scheme:
Treat a Chinese medicine composition for insufficiency of stomach-QI, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Fructus Gardeniae 5-15 part, Rhizoma Coptidis 5-15 part, Herba Taraxaci 20-40 part, Fructus Aurantii 5-15 part, Radix Paeoniae Alba 10-20 part, Radix Bupleuri 5-15 part, Radix Glycyrrhizae 5-15 part, Concha Arcae (calcined) 5-15 part, Fructus Amomi 5-15 part.
Formula optimization is:
9 parts of Fructus Gardeniae Preparatuss, 9 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 9 parts of Fructus Aurantii (parched), 15 parts of Radix Paeoniae Alba, 10 parts of Radix Bupleuri, 6 parts of Radix Glycyrrhizae Preparatas, 10 parts of Concha Arcae (calcined), 10 parts of Fructus Amomis.
Preparation method:
Get by weight ratio above-mentioned raw material of Chinese medicine, concoct qualified after, decoct with water, decocting liquid filters, filtrate simmer down to clear paste adds ethanol and makes to reach 50-60% containing alcohol amount after clear paste lets cool, stir evenly, and leaves standstill, and filters; Filtrate recycling ethanol, is concentrated into thick paste, and thick paste is the former medicine that is rich in active component, then uses conventional means on pharmaceutics that former medicine is made to various common formulations.
Form being described in detail as follows of each raw material of Chinese medicine of the present invention:
Fructus Gardeniae: bitter in the mouth, cold in nature.GUIXIN, lung, tri-jiao channel.There is pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, the effects such as removing pathogenic heat from blood and toxic substance from the body.After burnt system, can reduce it cold.Research shows: after Fructus Gardeniae water decoction or granule or powder preparation to be taken after being infused in boiling water are oral to people, do gallbladder film making, after proving to take medicine, 20-40 minute gallbladder has obvious contraction.In addition, also there is the effects such as calmness, blood pressure lowering, antimicrobial, the healing of acceleration soft tissue.
Rhizoma Coptidis: bitter in the mouth, cold in nature.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.There is heat clearing and damp drying, the effects such as eliminating fire and detoxication.Be usually used in damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, the auditory meatus disease such as suppurate.Research shows: this product also all has stronger bacteriostasis to Hemolytic streptococcus, meningococcus, Diplococcus pneumoniae, vibrio cholera, anthrax bacillus and staphylococcus aureus; Dysentery bacterium, diphtheria corynebacterium, bacillus subtilis, viridans streptococci are all had to inhibitory action.In addition, this product also has the effects such as the bile secretion of lifting.
Herba Taraxaci: bitter in the mouth, sweet, cold in nature.Return liver, stomach warp.There is heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the effects such as inducing diuresis for treating stranguria syndrome.Be usually used in furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the diseases such as the puckery pain of pyretic stranguria.Experiment shows: Herba Taraxaci injection is dense in vitro has stronger bactericidal action to staphylococcus aureus resistance bacterial strain, Hemolytic streptococcus, to Diplococcus pneumoniae, meningococcus, diphtheria corynebacterium, bacillus pyocyaneus, Bacillus proteus, dysentery bacterium, Bacillus typhi etc. and micrococcus catarrhalis also have certain bactericidal action.In addition, this product also has, function of gallbladder promoting, diuresis stomach invigorating, the effects such as hypocatharsis.
Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.There is regulating the flow of QI to ease the stomach, the effects such as the stagnant relieving distension of row.Be usually used in the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, the sub-official disease such as prolapse.Zoopery shows: Fructus Aurantii Immaturus decoct is inhibitory action to mice intestine in vitro part, and rabbits infestines is all performance inhibition.This effect can be by acetylcholine institute antagonism.But after dog gavage 100% Fructus Aurantii Immaturus to stomach flaccidity and intestinal flaccidity, have excitation, can make gastrointestinal motility shrink the rhythm and pace of moving things increases.Give dog gavage 100% concentrated Fructus Aurantii Immaturus liquid 1ml/kg, the cycle of visible small intestinal interdigestive myoelectric complex and I phase time-histories shorten, and II phase time-histories extends.Show that Fructus Aurantii Immaturus has the intestinal smooth muscle of enhancing tensity and position phasic property contractile function.
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.Return liver, spleen channel.There is suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, the effects such as astringing YIN to stop sweating.Be usually used in having a headache dizzy, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, the diseases such as night sweat.Experiment shows: this product have analgesia, spasmolytic, antiinflammatory, antiulcer, promotion macrophage phagocytic function, blood vessel dilating, increase organic blood flow volume, anticoagulant, broad-spectrum antiseptic, protect the liver and the effect such as removing toxic substances.
Radix Bupleuri: bitter in the mouth, cold nature.Return liver, gallbladder meridian.There is reconciling superficies and interior, soothing the liver, the effects such as yang invigorating.Be usually used in cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, the diseases such as proctoptosis.Research shows: this product also have antipyretic, calm, ease pain, protect the liver, antiinflammatory, function of gallbladder promoting and improve the content of cholic acid, the red matter of gallbladder in bile, the effect such as cholesterol-cholate coefficient that increases bile.
Radix Glycyrrhizae: sweet in the mouth, property is flat.GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effects such as coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, the disease such as strong.The aqueous extract of Radix Glycyrrhizae has the effect of protection gastric mucosa.
Concha Arcae: salty in the mouth, property is flat.Return lung, stomach, Liver Channel.There is expectorant blood stasis dispelling, hard masses softening and resolving, the effects such as relieving gastric hyperacidity to alleviate stomachache.Be usually used in the long-pending knot of pertinacious phlegm, sticky difficulty is coughed up, goiter, scrofula, lump in the abdomen mass in the abdomen, the diseases such as stomachache pantothenic acid.
Fructus Amomi: acrid in the mouth, warm in nature.Return spleen, stomach, kidney channel.There is removing dampness appetizing, warming spleen and stopping diarrha, the effect such as regulate the flow of vital energy antiabortive.Be usually used in turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, the diseases such as frequent fetal movement.This product is inhibited to intestinal tube smooth muscle; Can promote intestinal movement; Obviously anticoagulant; The effects such as antiulcer.
Use optimization formula to make crude drug for zoopery:
The large, medium and small dosage group of medicine of the present invention (18g crude drug/kg, 9g crude drug/kg, 4.5g crude drug/kg, be equivalent to respectively 18,9,4.5 times of quantity), Epidemiological Analysis and model group comparison by statistics, with model group comparison, each dosage group Turnover of Mouse Peritoneal Macrophages is engulfed CRBC percentage rate and is all obviously increased (p < 0.05), illustrates that medicine of the present invention can strengthen the phagocytic activity of mice with spleen deficiency macrophage.
The large, medium and small dosage group of medicine of the present invention (18g crude drug/kg, 9g crude drug/kg, 4.5g crude drug/kg, be equivalent to respectively 18,9,4.5 times of quantity), Epidemiological Analysis by statistics, with the comparison of normal saline group, the progradation of each dosage group mouse small intestine is (P < 0.05) obviously, illustrates that medicine of the present invention has the function that promotes mice enterokinesia.
Medicine of the present invention can be by promoting enterokinesia as can be seen here, improve fuselage state and gastroenteritic power function and reach facilitating digestion, promote the effect of appetite, therefore cause for insufficiency of stomach-QI as stomach distending pain, be off one's feed, lassitude, it is good that the idle disease such as weak of body has therapeutic effect, vital base and primordial QI consolidating, treatment cost is lower, and toxic and side effects is little, controls the advantages such as recurrence rate after healing is low.
Detailed description of the invention:
Embodiment 1:
Treat a Chinese medicine composition for insufficiency of stomach-QI, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 9 parts of Fructus Gardeniae Preparatuss, 9 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 9 parts of Fructus Aurantii (parched), 15 parts of Radix Paeoniae Alba, 10 parts of Radix Bupleuri, 6 parts of Radix Glycyrrhizae Preparatas, 10 parts of Concha Arcae (calcined), 10 parts of Fructus Amomis.
Preparation method:
Get by weight ratio above-mentioned raw material of Chinese medicine, concoct qualified after, decoct with water, decocting liquid filters, filtrate simmer down to clear paste adds ethanol and makes to reach 50-60% containing alcohol amount after clear paste lets cool, stir evenly, and leaves standstill, and filters; Filtrate recycling ethanol, is concentrated into thick paste, and thick paste is the former medicine that is rich in active component, then uses conventional means on pharmaceutics that former medicine is made to various common formulations.
Embodiment 2:
Treat a Chinese medicine composition for insufficiency of stomach-QI, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 5 parts of Fructus Gardeniaes, 5 parts of Rhizoma Coptidis, 20 parts of Herba Taraxacis, 5 parts of Fructus Aurantiis, 10 parts of the Radix Paeoniae Albas, 5 parts of Radix Bupleuri, 8 parts, Radix Glycyrrhizae, 5 parts of Concha Arcae (calcined), 8 parts of Fructus Amomis.
Preparation method:
Get by weight ratio above-mentioned raw material of Chinese medicine, concoct qualified after, decoct with water, decocting liquid filters, filtrate simmer down to clear paste adds ethanol and makes to reach 50-60% containing alcohol amount after clear paste lets cool, stir evenly, and leaves standstill, and filters; Filtrate recycling ethanol, is concentrated into thick paste, and thick paste is the former medicine that is rich in active component, then uses conventional means on pharmaceutics that former medicine is made to various common formulations.
Embodiment 3:
Treat a Chinese medicine composition for insufficiency of stomach-QI, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 15 parts of Fructus Gardeniaes, 10 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 15 parts of Fructus Aurantiis, 20 parts of the Radix Paeoniae Albas, 15 parts of Radix Bupleuri, 10 parts, Radix Glycyrrhizae, 10 parts of Concha Arcae (calcined), 13 parts of Fructus Amomis.
Preparation method:
Get by weight ratio above-mentioned raw material of Chinese medicine, concoct qualified after, decoct with water, decocting liquid filters, filtrate simmer down to clear paste adds ethanol and makes to reach 50-60% containing alcohol amount after clear paste lets cool, stir evenly, and leaves standstill, and filters; Filtrate recycling ethanol, is concentrated into thick paste, and thick paste is the former medicine that is rich in active component, then uses conventional means on pharmaceutics that former medicine is made to various common formulations.
The explanation of taking medicine:
Take medicine every day 3 times, each serving the preparation with containing 15 grams of crude drugs, individual hour of every flavour 7-9 between taking medicine for twice, taking medicine continuously 1 week is a course for the treatment of; Period in a medicine must not eat cold and cool, greasy and irritable food, keeps good work and rest rule.

Claims (2)

1. treat the Chinese medicine composition of insufficiency of stomach-QI for one kind, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: Fructus Gardeniae Preparatus 5-15 part, Rhizoma Coptidis 5-15 part, Herba Taraxaci 20-40 part, Fructus Aurantii (parched) 5-15 part, Radix Paeoniae Alba 10-20 part, Radix Bupleuri 5-15 part, Radix Glycyrrhizae Preparata 5-15 part, Concha Arcae (calcined) 5-15 part, Fructus Amomi 5-15 part.
2. according to a kind of Chinese medicine composition for the treatment of insufficiency of stomach-QI described in claim 1, it is characterized in that being made by the raw material of Chinese medicine of following weight proportion: 9 parts of Fructus Gardeniae Preparatuss, 9 parts of Rhizoma Coptidis, 30 parts of Herba Taraxacis, 9 parts of Fructus Aurantii (parched), 15 parts of Radix Paeoniae Alba, 10 parts of Radix Bupleuri, 6 parts of Radix Glycyrrhizae Preparatas, 10 parts of Concha Arcae (calcined), 10 parts of Fructus Amomis.
CN201410233241.0A 2014-05-29 2014-05-29 Traditional Chinese medicine composition for treating stomach Qi deficiency Pending CN103961630A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105831744A (en) * 2016-03-31 2016-08-10 李水平 A conditioning meal for conditioning body constitutions with qi deficiency and a preparing method thereof
CN111729053A (en) * 2020-07-10 2020-10-02 张家口义王堂生物科技有限责任公司 Traditional Chinese medicine composition for soothing liver and harmonizing stomach, Weitean pill and preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
徐江雁等: "李振华教授调理脾胃用药规律探讨", 《河南中医》 *
翟金环: "补中益气汤临床运用3则", 《中医药临床杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105831744A (en) * 2016-03-31 2016-08-10 李水平 A conditioning meal for conditioning body constitutions with qi deficiency and a preparing method thereof
CN111729053A (en) * 2020-07-10 2020-10-02 张家口义王堂生物科技有限责任公司 Traditional Chinese medicine composition for soothing liver and harmonizing stomach, Weitean pill and preparation method

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Application publication date: 20140806