CN105831744A - A conditioning meal for conditioning body constitutions with qi deficiency and a preparing method thereof - Google Patents
A conditioning meal for conditioning body constitutions with qi deficiency and a preparing method thereof Download PDFInfo
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- CN105831744A CN105831744A CN201610216652.8A CN201610216652A CN105831744A CN 105831744 A CN105831744 A CN 105831744A CN 201610216652 A CN201610216652 A CN 201610216652A CN 105831744 A CN105831744 A CN 105831744A
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- 230000003750 conditioning effect Effects 0.000 title claims abstract description 28
- 230000007812 deficiency Effects 0.000 title claims abstract description 27
- 235000012054 meals Nutrition 0.000 title claims abstract description 20
- 238000000034 method Methods 0.000 title abstract description 5
- 239000002994 raw material Substances 0.000 claims abstract description 21
- 238000000605 extraction Methods 0.000 claims abstract description 18
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 17
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 17
- 235000008434 ginseng Nutrition 0.000 claims abstract description 17
- 235000021551 crystal sugar Nutrition 0.000 claims abstract description 9
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 64
- 239000000706 filtrate Substances 0.000 claims description 48
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 46
- 210000000582 semen Anatomy 0.000 claims description 42
- 239000003208 petroleum Substances 0.000 claims description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 26
- 239000012153 distilled water Substances 0.000 claims description 25
- 239000000284 extract Substances 0.000 claims description 18
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 16
- 241000208340 Araliaceae Species 0.000 claims description 16
- 239000003456 ion exchange resin Substances 0.000 claims description 16
- 229920003303 ion-exchange polymer Polymers 0.000 claims description 16
- 239000007864 aqueous solution Substances 0.000 claims description 14
- 230000000474 nursing effect Effects 0.000 claims description 13
- 238000002360 preparation method Methods 0.000 claims description 11
- 239000012259 ether extract Substances 0.000 claims description 9
- 239000011347 resin Substances 0.000 claims description 9
- 229920005989 resin Polymers 0.000 claims description 9
- 238000009835 boiling Methods 0.000 claims description 8
- 239000003480 eluent Substances 0.000 claims description 8
- 238000010828 elution Methods 0.000 claims description 8
- 150000002333 glycines Chemical class 0.000 claims description 8
- 238000000227 grinding Methods 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- 238000010992 reflux Methods 0.000 claims description 8
- 238000003756 stirring Methods 0.000 claims description 8
- 239000006071 cream Substances 0.000 claims description 3
- 238000002386 leaching Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 2
- 239000012467 final product Substances 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 abstract description 9
- 235000013339 cereals Nutrition 0.000 abstract description 6
- 229940079593 drug Drugs 0.000 abstract description 4
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 244000144730 Amygdalus persica Species 0.000 abstract 1
- 235000017060 Arachis glabrata Nutrition 0.000 abstract 1
- 244000105624 Arachis hypogaea Species 0.000 abstract 1
- 235000010777 Arachis hypogaea Nutrition 0.000 abstract 1
- 235000018262 Arachis monticola Nutrition 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 240000005717 Dioscorea alata Species 0.000 abstract 1
- 244000068988 Glycine max Species 0.000 abstract 1
- 235000010469 Glycine max Nutrition 0.000 abstract 1
- 235000018142 Hedysarum alpinum var americanum Nutrition 0.000 abstract 1
- 240000006461 Hedysarum alpinum var. americanum Species 0.000 abstract 1
- 244000017020 Ipomoea batatas Species 0.000 abstract 1
- 235000002678 Ipomoea batatas Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000006040 Prunus persica var persica Nutrition 0.000 abstract 1
- 244000062793 Sorghum vulgare Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 235000019713 millet Nutrition 0.000 abstract 1
- 235000020232 peanut Nutrition 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 6
- 230000006837 decompression Effects 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- 241000209094 Oryza Species 0.000 description 4
- 235000007164 Oryza sativa Nutrition 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 235000009566 rice Nutrition 0.000 description 4
- 102000001554 Hemoglobins Human genes 0.000 description 3
- 108010054147 Hemoglobins Proteins 0.000 description 3
- 241000411851 herbal medicine Species 0.000 description 3
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- 235000013305 food Nutrition 0.000 description 2
- 238000010172 mouse model Methods 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 241000825107 Hierochloe Species 0.000 description 1
- 235000015466 Hierochloe odorata Nutrition 0.000 description 1
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- 238000010241 blood sampling Methods 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
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- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 235000020805 dietary restrictions Nutrition 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 230000002984 haematinic effect Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
A conditioning meal for conditioning body constitutions with qi deficiency is disclosed. The meal is prepared from 8-12 parts by weight of common yam rhizome, 8-12 parts by weight of millet, 8-12 parts by weight of dried tangerine peel, 8-12 parts by weight of peanut, 5-10 parts by weight of poria, 8-12 parts by weight of soybean, 5-10 parts by weight of ginseng, 8-12 parts by weight of dried sweet potato, 5-10 parts by weight of liquorice root, 10-15 parts by weight of crystal sugar, 1-5 parts by weight of cassia seed, 1-5 parts by weight of dandelion and 1-5 parts by weight of peach seeds. Through adopting Chinese herb medicines and the five cereals as raw materials and adopting a special extraction and preparing method, the conditioning meal having significant conditioning effects and no side effects, combining the Chinese herb medicines and refined and coarse grains and used for conditioning the body constitutions with the qi deficiency is prepared.
Description
Technical field
The present invention relates to a kind of conditioning meal nursing one's health Qi deficiency physique and preparation method thereof, belong to Chinese medicine
Field.
Technical background
Qi deficiency physique refers to, when the biochemistry of human-body viscera function imbalance, gas is not enough, easily occur
The deficiency of vital energy shows, and fosters the spirit of nobility as general provisions with QI invigorating, selects respectively and mends qi of zang-fu viscera combination.According to QI and blood
Homology suitably adds uses hematonic.
Medicine and the food of existing conditioning Qi deficiency physique are more single, and effect is undesirable.
Summary of the invention
It is an object of the invention to provide a kind of conditioning meal nursing one's health Qi deficiency physique and preparation method thereof,
Using Chinese herbal medicine grain rice is raw material, then with specifically extracting compound method, prepares conditioning effect and show
Write, the conditioning meal of the Chinese herbal medicine mixed grain rice combination conditioning Qi deficiency physique having no side effect.
A kind of conditioning meal nursing one's health Qi deficiency physique, is made up of the raw material of following masses number: Rhizoma Dioscoreae
8-12 part, Semen setariae 8-12 part, Pericarpium Citri Reticulatae 8-12 part, Semen arachidis hypogaeae 8-12 part, Poria 5-10 part,
Semen Glycines 8-12 part, Radix Ginseng 5-10 part, dried Radix Ipomoeae Batattis 8-12 part, Radix Glycyrrhizae 5-10 part, crystal sugar
10-15 part, Semen Cassiae 1-5 part, Herba Taraxaci 1-5 part, Semen Persicae 1-5 part.
A kind of conditioning meal nursing one's health Qi deficiency physique, its preparation method is:
(1) being pulverized by Radix Ginseng, 75% ethanol 70-80 DEG C adding 3-5 times of quality is heated to reflux
60-100 minute, filtering, obtain filtrate, it is 1.05-1.10 that filtrate reduced in volume is obtained relative density
Extractum, then the distilled water adding extractum 1.5-2.5 times dissolves, and obtains aqueous solution, continues with water-soluble
The petroleum ether extraction of 1.2-1.4 times of volume of liquid, obtains petroleum ether extract, recovered under reduced pressure petroleum ether,
Obtain extract standby；
(2) Semen Cassiae is pulverized, add the distilled water 60-70 DEG C of extraction of heating of 6-8 times of quality
100-120 minute, filter, obtain filtrate, upper for filtrate HZ002 type ion exchange resin column,
Again with 50% ethanol of 1BV, 70% ethanol of 1BV, 90% ethanol gradient elution of 1BV, receive
Collection eluent, concentrating under reduced pressure obtains the extractum that density is 1.05-1.07, standby；
(3) Radix Glycyrrhizae and Herba Taraxaci being pulverized and mixed, the distilled water adding 2-4 times of mixture quality surpasses
Sound extracts 15-25 minute, filters, obtains filtrate, and concentrating under reduced pressure obtains the leaching that density is 1.04-1.06
Cream, standby；
(4) remaining raw material is pulverized respectively, and step (1) is extract obtained, step (2)
Gained extractum, step (3) gained extractum, put in mixed cylinder, stir 100-140 minute,
Under the conditions of 60-70 DEG C, dry compacting with low temperature baking device again, finally use Ultra-Micro Grinding Equipment
Pulverize, to obtain final product.
Wherein, the boiling range of the petroleum ether in step (1) is 60-90 DEG C.
Wherein, in step (2), the volume ratio of filtrate and HZ002 type ion exchange resin is
1: 0.6-0.8, the height of resin column and diameter ratio are 4: 1.
Chinese herbal medicine grain rice of the present invention combination is under Traditional Chinese medical theory and clinical experience instruct, essence
Choosing medical herbs and grain rice combination, formula is simple, it then follows theory of Chinese medical science combination principle, then uses spy
Fixed Traditional Chinese medicine extraction method, finally bakees superfine communication technique with low temperature, reconstitutes through boiled water
Drinking, empirical tests conditioning deficiency of vital energy effect is notable, and integration of edible and medicinal herbs edible safety is reliable,
Specific embodiment
Embodiment 1:
A kind of conditioning meal nursing one's health Qi deficiency physique, is made up of the raw material of following masses number: Rhizoma Dioscoreae
8 parts, Semen setariae 8 parts, Pericarpium Citri Reticulatae 8 parts, Semen arachidis hypogaeae 8 parts, 5 parts of Poria, Semen Glycines 8 parts, Radix Ginseng
5 parts, dried Radix Ipomoeae Batattis 8 parts, 5 parts of Radix Glycyrrhizae, 10 parts of crystal sugar, Semen Cassiae 1 part, Herba Taraxaci 1 part,
1 part of Semen Persicae.
Its preparation method is:
(1) being pulverized by Radix Ginseng, 75% ethanol 70 DEG C adding 3 times of quality is heated to reflux 60 minutes,
Filter, obtain filtrate, filtrate reduced in volume is obtained the extractum that relative density is 1.05, then adds leaching
The distilled water that cream is 1.5 times dissolves, and obtains aqueous solution, continues with the oil of 1.2 times of volumes of aqueous solution
Ether extracts, and obtains petroleum ether extract, recovered under reduced pressure petroleum ether, obtains extract standby；
(2) being pulverized by Semen Cassiae, the distilled water adding 6 times of quality heats 60 DEG C of extractions 100 minutes,
Filter, obtain filtrate, upper for filtrate HZ002 type ion exchange resin column, then with the 50% of 1BV
Ethanol, 70% ethanol of 1BV, 90% ethanol gradient elution of 1BV, collect eluent, decompression
It is concentrated to give the extractum that density is 1.05, standby；
(3) Radix Glycyrrhizae and Herba Taraxaci being pulverized and mixed, the distilled water adding 2 times of mixture qualities is ultrasonic
Extracting 15 minutes, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.04, standby；
(4) remaining raw material is pulverized respectively, and step (1) is extract obtained, step (2)
Gained extractum, step (3) gained extractum, put in mixed cylinder, stir 100 minutes, then
Under the conditions of 60 DEG C, dry compacting with low temperature baking device, finally pulverize with Ultra-Micro Grinding Equipment,
Obtain.
Wherein, the boiling range of the petroleum ether in step (1) is 60-90 DEG C.
Wherein, in step (2), the volume ratio of filtrate and HZ002 type ion exchange resin is
1: 0.6, the height of resin column and diameter ratio are 4: 1.
Embodiment 2:
A kind of conditioning meal nursing one's health Qi deficiency physique, is made up of the raw material of following masses number: Rhizoma Dioscoreae
10 parts, Semen setariae 10 parts, Pericarpium Citri Reticulatae 10 parts, Semen arachidis hypogaeae 10 parts, 8 parts of Poria, Semen Glycines 10 parts,
Radix Ginseng 8 parts, dried Radix Ipomoeae Batattis 10 parts, 8 parts of Radix Glycyrrhizae, 12 parts of crystal sugar, Semen Cassiae 3 parts, Pu Gong
English 3 parts, 3 parts of Semen Persicae.
Its preparation method is:
(1) being pulverized by Radix Ginseng, 75% ethanol 75 DEG C adding 3-5 times of quality is heated to reflux 80 points
Clock, filters, obtains filtrate, filtrate reduced in volume is obtained the extractum that relative density is 1.08, then
The distilled water adding extractum 2.0 times dissolves, and obtains aqueous solution, continues with 1.3 times of volumes of aqueous solution
Petroleum ether extraction, obtains petroleum ether extract, recovered under reduced pressure petroleum ether, obtains extract standby；
(2) being pulverized by Semen Cassiae, the distilled water adding 7 times of quality heats 65 DEG C of extractions 110 minutes,
Filter, obtain filtrate, upper for filtrate HZ002 type ion exchange resin column, then with the 50% of 1BV
Ethanol, 70% ethanol of 1BV, 90% ethanol gradient elution of 1BV, collect eluent, decompression
It is concentrated to give the extractum that density is 1.06, standby；
(3) Radix Glycyrrhizae and Herba Taraxaci being pulverized and mixed, the distilled water adding 3 times of mixture qualities is ultrasonic
Extracting 20 minutes, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.05, standby；
(4) remaining raw material is pulverized respectively, and step (1) is extract obtained, step (2)
Gained extractum, step (3) gained extractum, put in mixed cylinder, stir 120 minutes, then
Under the conditions of 65 DEG C, dry compacting with low temperature baking device, finally pulverize with Ultra-Micro Grinding Equipment,
Obtain.
Wherein, the boiling range of the petroleum ether in step (1) is 60-90 DEG C.
Wherein, in step (2), the volume ratio of filtrate and HZ002 type ion exchange resin is
1: 0.7, the height of resin column and diameter ratio are 4: 1.
Embodiment 3:
A kind of conditioning meal nursing one's health Qi deficiency physique, is made up of the raw material of following masses number: Rhizoma Dioscoreae
12 parts, Semen setariae 12 parts, Pericarpium Citri Reticulatae 12 parts, Semen arachidis hypogaeae 12 parts, 10 parts of Poria, Semen Glycines 12 parts,
Radix Ginseng 10 parts, dried Radix Ipomoeae Batattis 12 parts, 10 parts of Radix Glycyrrhizae, 15 parts of crystal sugar, Semen Cassiae 5 parts, Pu
Herba Taraxaci 5 parts, 5 parts of Semen Persicae.
Its preparation method is:
(1) being pulverized by Radix Ginseng, 75% ethanol 80 DEG C adding 3-5 times of quality is heated to reflux 100
Minute, filter, obtain filtrate, filtrate reduced in volume is obtained the extractum that relative density is 1.10,
The distilled water adding extractum 2.5 times again dissolves, and obtains aqueous solution, continues with 1.4 times of volumes of aqueous solution
Petroleum ether extraction, obtain petroleum ether extract, recovered under reduced pressure petroleum ether, obtain extract standby；
(2) being pulverized by Semen Cassiae, the distilled water adding 8 times of quality heats 70 DEG C of extractions 120 minutes,
Filter, obtain filtrate, upper for filtrate HZ002 type ion exchange resin column, then with the 50% of 1BV
Ethanol, 70% ethanol of 1BV, 90% ethanol gradient elution of 1BV, collect eluent, decompression
It is concentrated to give the extractum that density is 1.07, standby；
(3) Radix Glycyrrhizae and Herba Taraxaci being pulverized and mixed, the distilled water adding 4 times of mixture qualities is ultrasonic
Extracting 25 minutes, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.06, standby；
(4) remaining raw material is pulverized respectively, and step (1) is extract obtained, step (2)
Gained extractum, step (3) gained extractum, put in mixed cylinder, stir 140 minutes, then
Under the conditions of 70 DEG C, dry compacting with low temperature baking device, finally pulverize with Ultra-Micro Grinding Equipment,
Obtain.
Wherein, the boiling range of the petroleum ether in step (1) is 60-90 DEG C.
Wherein, in step (2), the volume ratio of filtrate and HZ002 type ion exchange resin is 1:
0.8, the height of resin column and diameter ratio are 4: 1.
Embodiment 4:
A kind of conditioning meal nursing one's health Qi deficiency physique, is made up of the raw material of following masses number: Rhizoma Dioscoreae
6 parts, Semen setariae 15 parts, Pericarpium Citri Reticulatae 6 parts, Semen arachidis hypogaeae 15 parts, 4 parts of Poria, Semen Glycines 15 parts,
Radix Ginseng 4 parts, dried Radix Ipomoeae Batattis 15 parts, 4 parts of Radix Glycyrrhizae, 8 parts of crystal sugar, Semen Cassiae 6 parts, Herba Taraxaci
0.5 part, 6 parts of Semen Persicae.
Its preparation method is:
(1) being pulverized by Radix Ginseng, 75% ethanol 85 DEG C adding 3-5 times of quality is heated to reflux 50 points
Clock, filters, obtains filtrate, filtrate reduced in volume is obtained the extractum that relative density is 1.03, then
The distilled water adding extractum 3.0 times dissolves, and obtains aqueous solution, continues with 1.5 times of volumes of aqueous solution
Petroleum ether extraction, obtains petroleum ether extract, recovered under reduced pressure petroleum ether, obtains extract standby；
(2) being pulverized by Semen Cassiae, the distilled water adding 5 times of quality heats 80 DEG C of extractions 140 minutes,
Filter, obtain filtrate, upper for filtrate HZ002 type ion exchange resin column, then with the 50% of 1BV
Ethanol, 70% ethanol of 1BV, 90% ethanol gradient elution of 1BV, collect eluent, decompression
It is concentrated to give the extractum that density is 1.08, standby；
(3) Radix Glycyrrhizae and Herba Taraxaci being pulverized and mixed, the distilled water adding 5 times of mixture qualities is ultrasonic
Extracting 10 minutes, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.08, standby；
(4) remaining raw material is pulverized respectively, and step (1) is extract obtained, step (2)
Gained extractum, step (3) gained extractum, put in mixed cylinder, stir 150 minutes, then
Under the conditions of 80 DEG C, dry compacting with low temperature baking device, finally pulverize with Ultra-Micro Grinding Equipment,
Obtain.
Wherein, the boiling range of the petroleum ether in step (1) is 60-90 DEG C.
Wherein, in step (2), the volume ratio of filtrate and HZ002 type ion exchange resin is
1: 0.5, the height of resin column and diameter ratio are 4: 1.
Embodiment 5:
A kind of conditioning meal nursing one's health Qi deficiency physique, is made up of the raw material of following masses number: Rhizoma Dioscoreae
9 parts, Semen setariae 10 parts, Pericarpium Citri Reticulatae 12 parts, Semen arachidis hypogaeae 9 parts, Semen Glycines 8 parts, Radix Ginseng 6 parts, sweet
Grass 6 parts, 10 parts of crystal sugar, Semen Cassiae 2 parts, Herba Taraxaci 2 parts.
Its preparation method is:
(1) being pulverized by Radix Ginseng, 75% ethanol 780 DEG C adding 3-5 times of quality is heated to reflux 70
Minute, filter, obtain filtrate, filtrate reduced in volume is obtained the extractum that relative density is 1.06,
The distilled water adding extractum 1.5 times again dissolves, and obtains aqueous solution, continues with 1.4 times of volumes of aqueous solution
Petroleum ether extraction, obtain petroleum ether extract, recovered under reduced pressure petroleum ether, obtain extract standby；
(2) being pulverized by Semen Cassiae, the distilled water adding 6-8 times of quality heats 70 DEG C of extractions 100 minutes,
Filter, obtain filtrate, upper for filtrate HZ002 type ion exchange resin column, then with the 50% of 1BV
Ethanol, 70% ethanol of 1BV, 90% ethanol gradient elution of 1BV, collect eluent, decompression
It is concentrated to give the extractum that density is 1.06, standby；
(3) Radix Glycyrrhizae and Herba Taraxaci being pulverized and mixed, the distilled water adding 4 times of mixture qualities is ultrasonic
Extracting 125 minutes, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.04, standby；
(4) remaining raw material is pulverized respectively, and step (1) is extract obtained, step (2)
Gained extractum, step (3) gained extractum, put in mixed cylinder, stir 140 minutes, then
Under the conditions of 60 DEG C, dry compacting with low temperature baking device, finally pulverize with Ultra-Micro Grinding Equipment,
Obtain.
Wherein, the boiling range of the petroleum ether in step (1) is 60-90 DEG C.
Wherein, in step (2), the volume ratio of filtrate and HZ002 type ion exchange resin is
1: 0.6, the height of resin column and diameter ratio are 4: 1.
Embodiment 6:
A kind of conditioning meal nursing one's health Qi deficiency physique, is made up of the raw material of following masses number: Rhizoma Dioscoreae
12 parts, Semen setariae 11 parts, Pericarpium Citri Reticulatae 9 parts, Semen arachidis hypogaeae 8 parts, 9 parts of Poria, Semen Glycines 10 parts,
Radix Ginseng 8 parts, dried Radix Ipomoeae Batattis 10 parts, 7 parts of Radix Glycyrrhizae, 12 parts of crystal sugar, Semen Cassiae 4 parts, Pu Gong
English 4 parts, 4 parts of Semen Persicae.
Its preparation method is:
(1) being pulverized by Radix Ginseng, 75% ethanol 70 DEG C adding 3-5 times of quality is heated to reflux 90 points
Clock, filters, obtains filtrate, filtrate reduced in volume is obtained the extractum that relative density is 1.07, then
The distilled water adding extractum 2.0 times dissolves, and obtains aqueous solution, continues with 1.4 times of volumes of aqueous solution
Petroleum ether extraction, obtains petroleum ether extract, recovered under reduced pressure petroleum ether, obtains extract standby；
(2) being pulverized and mixed by Semen Cassiae, the distilled water adding 7 times of quality heats 60-70 DEG C of extraction 120
Minute, filter, obtain filtrate, upper for filtrate D241 type ion exchange resin column, then use 1BV
50% ethanol, 70% ethanol of 1BV, 90% ethanol gradient elution of 1BV, collect eluent,
Concentrating under reduced pressure obtains the extractum that density is 1.07, standby；
(3) Radix Glycyrrhizae and Herba Taraxaci being pulverized and mixed, the distilled water adding 2 times of mixture qualities is ultrasonic
Extracting 25 minutes, filter, obtain filtrate, concentrating under reduced pressure obtains the extractum that density is 1.06, standby；
(4) remaining raw material is pulverized respectively, and step (1) is extract obtained, step (2)
Gained extractum, step (3) gained extractum, put in mixed cylinder, stir 100 minutes, then
Under the conditions of 70 DEG C, dry compacting with low temperature baking device, finally pulverize with Ultra-Micro Grinding Equipment,
Obtain.
Wherein, the boiling range of the petroleum ether in step (1) is 60-90 DEG C.
Wherein, in step (2), the volume ratio of filtrate and HZ002 type ion exchange resin is
1: 0.7, the height of resin column and diameter ratio are 4: 1.
Effect experimental:
Impact on mice model of qi-asthenia:
Animal KM kind mice 80, is randomly divided into Normal group, model control group, embodiment
1-6 group (2.0g/kg), often group 10.Testing the 1st day, animal starts ig and is administered, matched group
Give equivalent distilled water, continuous 10d.Use limit food to add purgative therapy and cause mice model of qi-asthenia, remove
Outside Normal group, in test respectively group beginning dietary restriction 10d (dietary amount restriction every day in the 1st day
For 100g/kg), (the crude drug amount that every milliliter contains is 1 to ig every day 100% Radix Et Rhizoma Rhei decocting liquid simultaneously
G) 20mL/kg body weight, causes mice " deficiency of vital energy " model.1h after being administered in the 9th day, eye socket
Blood sampling, measures peripheral red blood cells counting, content of hemoglobin on automatic hematology analyzer.
1h after last administration, carries out walking weight load mensuration.Result is as shown in table 1 below:
Table 1 present invention is to deficiency of vital energy animal model swimming time, RBC number, the shadow of content of hemoglobin
Ring
| Group | Swimming time/s | RBC/×1012/L | HGB/g·L-1 |
| Normal group | 180.52±25.27 | 12.68±0.56 | 17.74±1.01 |
| Model control group | 90.50±13.05 | 10.38±0.70 | 15.58±0.64 |
| Embodiment 1 group | 151.76±23.49 | 12.01±0.52 | 17.12±0.95 |
| Embodiment 2 groups | 158.86±22.16 | 12.46±0.55 | 17.45±0.92 |
| Embodiment 3 groups | 155.25±22.73 | 12.25±0.62 | 17.37±0.87 |
| Embodiment 4 groups | 130.31±18.68 | 11.73±0.51 | 16.53±0.83 |
| Embodiment 5 groups | 123.69±16.98 | 11.26±0.47 | 16.09±0.78 |
| Embodiment 6 groups | 125.13±17.30 | 11.52±0.50 | 16.36±0.85 |
From upper table data it can be seen that can be notable for deficiency of vital energy mice in embodiment of the present invention 1-3
Increasing the swimming time of deficiency of vital energy mice, erythrocyte number and content of hemoglobin, effect is the most obvious
Be better than embodiment 4 groups (technological parameter different), embodiment 5 groups (few a few herbs raw material),
Embodiment 6 groups (uses other resin columns to extract), it is seen that the technological parameter of the present invention,
Raw material of Chinese medicine, extraction process all have shadow to the effect of the conditioning meal of prepared conditioning Qi deficiency physique
Ring, therefore present invention employs specific technological parameter, raw material of Chinese medicine synergism, specifically
Extracting technique of Chinese medicine, could prepare effect and significantly nurse one's health the conditioning meal of Qi deficiency physique.
Claims (2)
1. the conditioning meal nursing one's health Qi deficiency physique, is characterized by: by following masses number
Raw material is made: Rhizoma Dioscoreae 8-12 part, Semen setariae 8-12 part, Pericarpium Citri Reticulatae 8-12 part, Semen arachidis hypogaeae 8-12 part,
Poria 5-10 part, Semen Glycines 8-12 part, Radix Ginseng 5-10 part, dried Radix Ipomoeae Batattis 8-12 part, Radix Glycyrrhizae
5-10 part, crystal sugar 10-15 part, Semen Cassiae 1-5 part, Herba Taraxaci 1-5 part, Semen Persicae 1-5 part.
A kind of conditioning meal nursing one's health Qi deficiency physique the most as claimed in claim 1, is characterized by:
Its preparation method is:
(1) being pulverized by Radix Ginseng, 75% ethanol 70-80 DEG C adding 3-5 times of quality is heated to reflux
60-100 minute, filtering, obtain filtrate, it is 1.05-1.10 that filtrate reduced in volume is obtained relative density
Extractum, then the distilled water adding extractum 1.5-2.5 times dissolves, and obtains aqueous solution, continues with water-soluble
The petroleum ether extraction of 1.2-1.4 times of volume of liquid, obtains petroleum ether extract, recovered under reduced pressure petroleum ether,
Obtain extract standby；
(2) Semen Cassiae is pulverized, add the distilled water 60-70 DEG C of extraction of heating of 6-8 times of quality
100-120 minute, filter, obtain filtrate, upper for filtrate HZ002 type ion exchange resin column,
Again with 50% ethanol of 1BV, 70% ethanol of 1BV, 90% ethanol gradient elution of 1BV, receive
Collection eluent, concentrating under reduced pressure obtains the extractum that density is 1.05-1.07, standby；
(3) Radix Glycyrrhizae and Herba Taraxaci being pulverized and mixed, the distilled water adding 2-4 times of mixture quality surpasses
Sound extracts 15-25 minute, filters, obtains filtrate, and concentrating under reduced pressure obtains the leaching that density is 1.04-1.06
Cream, standby；
(4) remaining raw material is pulverized respectively, and step (1) is extract obtained, step (2)
Gained extractum, step (3) gained extractum, put in mixed cylinder, stir 100-140 minute,
Under the conditions of 60-70 DEG C, dry compacting with low temperature baking device again, finally use Ultra-Micro Grinding Equipment
Pulverize, to obtain final product；
Wherein, the boiling range of the petroleum ether in step (1) is 60-90 DEG C；
Wherein, in step (2), the volume ratio of filtrate and HZ002 type ion exchange resin is
1: 0.6-0.8, the height of resin column and diameter ratio are 4: 1.
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455395A (en) * | 2009-01-05 | 2009-06-17 | 张明 | Medicated diet roasted-cake and production technique thereof |
| CN101816414A (en) * | 2009-02-27 | 2010-09-01 | 凌沛学 | Application of sunflower leaves for preparing foods and health-care foods for reducing blood pressure in auxiliary way |
| CN103463510A (en) * | 2013-08-16 | 2013-12-25 | 孟钧 | Traditional Chinese medicine for treatment of kidney deficiency and premature ejaculation |
| CN103621993A (en) * | 2012-08-28 | 2014-03-12 | 浙江劲膳美生物科技有限公司 | Dietary meal or meal replacement product for vital energy deficiency |
| CN103961630A (en) * | 2014-05-29 | 2014-08-06 | 蚌埠明日欣医药有限公司 | Traditional Chinese medicine composition for treating stomach Qi deficiency |
| CN104012950A (en) * | 2013-12-17 | 2014-09-03 | 胡安然 | Food for regulating qi-deficiency constitution |
| CN105031399A (en) * | 2015-08-07 | 2015-11-11 | 张玲亚 | Dietary supplement against deficiency of lung-spleen qi |
-
2016
- 2016-03-31 CN CN201610216652.8A patent/CN105831744A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101455395A (en) * | 2009-01-05 | 2009-06-17 | 张明 | Medicated diet roasted-cake and production technique thereof |
| CN101816414A (en) * | 2009-02-27 | 2010-09-01 | 凌沛学 | Application of sunflower leaves for preparing foods and health-care foods for reducing blood pressure in auxiliary way |
| CN103621993A (en) * | 2012-08-28 | 2014-03-12 | 浙江劲膳美生物科技有限公司 | Dietary meal or meal replacement product for vital energy deficiency |
| CN103463510A (en) * | 2013-08-16 | 2013-12-25 | 孟钧 | Traditional Chinese medicine for treatment of kidney deficiency and premature ejaculation |
| CN104012950A (en) * | 2013-12-17 | 2014-09-03 | 胡安然 | Food for regulating qi-deficiency constitution |
| CN103961630A (en) * | 2014-05-29 | 2014-08-06 | 蚌埠明日欣医药有限公司 | Traditional Chinese medicine composition for treating stomach Qi deficiency |
| CN105031399A (en) * | 2015-08-07 | 2015-11-11 | 张玲亚 | Dietary supplement against deficiency of lung-spleen qi |
Non-Patent Citations (1)
| Title |
|---|
| 史文丽等主编: "《五谷杂粮养生减肥粥》", 31 January 2016, 吉林科学技术出版社 * |
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Application publication date: 20160810 |