CN104189608B - Traditional Chinese medicine preparation for recurrent oral ulcer and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for recurrent oral ulcer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating recurrent oral ulceration and a preparation method thereof, and belongs to the traditional Chinese medicine field. The traditional Chinese medicine preparation comprises the following raw materials with effective components by weight part: radix cynanchi bungei, gynura bicolor 81, huperzia serrata, hemlock chervil, root of velutinous indigo, euphorbia humifusa, holly seed, acacia catechu, membrane of hen egg, wing nut leaf, adina pilulifera, radix achyranthis bidentatae, incarvillea sinensis, junci medulla, silkworm egg sheet and bitter bamboo leaf. The inventive traditional Chinese medicine preparation is processed by selecting the traditional Chinese medicinal material compositions which clear heat and detoxify, astringe sores and stop blood, diminish inflammation and remove swell, activate blood and relieve pain. The compatibility of medicines is suitable. The traditional Chinese medicine preparation has activating blood and detumescence, hemostasis and promoting granulation, and clearing heat and relieving restlessness effects, convenient use and good adsorption effect without bad or toxic and side effect. Checked by clinic, the traditional Chinese medicine preparation has wonderful relief and treatment effect to the recurrent oral ulceration, and is suitable for the recurrent oral ulceration clinic treatment and nursing popularization and application.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of recurrent oral ulceration.
Background technology
Recurrent oral ulceration is also known as recurrent aphtha, recurrent aphthous stomatitis, recurrent aphtha, it is a kind of disease that in oral keritonocytes, sickness rate is the highest, common cold, dyspepsia, psychentonia, the gloomy situation such as discomfort all accidentally can cause the generation of this disease, be apt to occur in lip, cheek, lingual margin etc., all can occur at any position of mucosa, but attached gingiva and hard palate are then rare completely in keratinization.Age of onset is generally between 10 ~ 30 years old, and women is more, all can occur throughout the year.
Recurrent aphtha has self limiting, can spontaneous recovery in about 10 days, there is the features such as periodicity, recurrent and self limiting, but can recur again after the intermission different in size, light-duty recurrent oral ulceration, herpesvirus type recurrent oral ulceration and heavy recurrent oral ulceration can be divided into.
Light-duty recurrent oral ulceration is from the beginning of lesion sensitivity or occur needle point sample size or slightly large congested district, namely forms diameter in a short time at about 2 ~ 4mm, circular or oval, sharply marginated shallow aphtha.Center micro-pits, surface is covered with the faint yellow pseudomembrane of one deck, and around ulcer, mucosa hyperemia is in blush shape, and it is not hard that its end lays one's hand on.Ulcer number is generally about 2 ~ 3.More violent burning pain is had after ulcer.Can spontaneous recovery gradually through about 7 ~ 10 days ulcer, do not stay cicatrix.But can recur again after the intermission different in size.
Herpesvirus type recurrent oral ulceration is also known as stomatitis type aphtha.This kind of is except ulcer is little, except number many (can reach 20 ~ 30), and all the other show similar to light-duty recurrent recurrent oral ulceration.KUIYANG SAN exists, widely distributed, and mucosa is obviously congested.To have an intense pain and with headache, heating, regional glandular enlargement etc.
Heavy recurrent oral ulceration, also known as Periadenitis mucosa periadenitis or periglandular aphthae, is a type the most serious in various.The normal single generation of ulcer, more than 2 or 2 persons are rare.Be apt to occur in inside lip and bicker district mucosa.From the beginning of time ulcer identical with light-duty recurrent oral ulceration, ulcer is aubergine or kermesinus, and edge is irregular, swells in flap, and concavity, like " crater ".The end, is uneven, micro-firmly, in brief summary nodular, blush around ulcer, local has an intense pain and can accompany regional glandular enlargement, heating etc.The course of disease be everlasting the moon remaining more than.More afterwards leave over cicatrix, severe patient can formative tissue defect or deformity.
Recurrent oral ulceration can multiple complications, and its harm should not be underestimated.Be used for the treatment of the medicine of recurrent oral ulceration disease at present mainly with anti-inflammation, antiallergic, local anesthesia analgesic type drug is made, but this type for the treatment of has certain side effect and dependency, therefore the necessary safety of medicine of recurrent oral ulceration is treated, effectively, have no side effect, and Chinese materia medica is as the traditional medicine of China, there is effect strong, instant effect, the advantages such as lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore a kind of Chinese medicine preparation is selected to treat recurrent oral ulceration, for treatment recurrent oral ulceration, there is very important clinical meaning.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and the preparation method that are used for the treatment of recurrent oral ulceration; The Chinese crude drug prescription of the selected heat-clearing and toxic substances removing of Chinese medicine preparation of the present invention, sore hemostasis, anti-inflammation detumescence, promoting blood circulation and stopping pain is concocted, compatibility is suitable, there is effect of promoting blood circulation and detumescence, hemostasia and promoting granulation, clearing heat and relieving fidgetness, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, there are fabulous alleviation and therapeutic effect to recurrent oral ulceration, are suitable for recurrent oral ulceration clinical treatment and nursing is applied.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for recurrent oral ulceration, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of recurrent oral ulceration, comprise following processing step:
(1) Radix Cynanchi Auriculati, hemlock chervil, Radix indigoferae stachyoidis, Ramulus et Folium Adinae Piluliferae and Radix Achyranthis Bidentatae are put decontamination, be placed in container, add the distilled water of 8 ~ 10 times amount, soak after 4 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 1 ~ 3 hour, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
(2) get Herba Gynurae bicoloris, catechu and Crusta Bombycis ovum decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) Herba Lycopodii serrati, Radix seu Caulis Parthenocissi tricuspidatae, Membrana Follicularis ovi and Herba Incarvilleae sinensis are stir-fried with high heat for several times, surface uniform sprays yellow wine, pulverizes, grind into powder after fried dry, crosses 180 order fine powders, for subsequent use;
(4) getting Fructus Ilicis Purpureae, Folium pterocaryae stenopterae, Medulla Junci and Folium Pleioblasti saline mixes thoroughly vexed, and with the micro-stir-fry of little fire, taking-up is dried, and is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(5) by the filtrate of step (1) gained, mix with the fine powder of step (4) gained with step (2), step (3), make buccal tablet, be the Chinese medicine preparation for the treatment of recurrent oral ulceration of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Cynanchi Auriculati: bitter in the mouth, sweet, puckery, slightly warm in nature; Return liver,kidney,spleen stomach warp.Invigorating the liver and kidney, bone and muscle strengthening, benefiting essence-blood, strengthening the spleen to promote digestion, detoxification sore treatment.For soreness of the waist and knees, impotence and seminal emission, dizziness and tinnitus, palpitation and insomnia, inappetence, infantile malnutrition, puerperal, milk was rare, sore, carbuncle and painful swelling." Shandong Chinese medicine " carries: " be nourishing, strong, hematonic, and can restrain vital essence, crow must hair color.Control prolonged illness weakness, anemia, early whitening of beard and hair, chronic migratory arthralgia, soreness of the waist and knees, sexual neurasthenie, hemorrhoid, enterorrhagia, deficiency of YIN chronic malaria, ulcer does not close up for a long time.Fresh and have the effect of loosening bowel to relieve constipation, be applicable to old people constipation.”
Herba Gynurae bicoloris: taste is micro-sweet, pungent, property is put down.Clearing away heat and cooling blood, removing toxic substances disappears.For hemoptysis, metrorrhagia, traumatic hemorrhage, dysmenorrhea, dysentery, sore swollen toxin, traumatic injury, ulcer does not restrain for a long time." Fujian Chinese herbal medicine " carries: " hemopoietic stops blooding, clearing heat for detumescence.”
Herba Lycopodii serrati: bitter in the mouth, micro-sweet, property is put down; Return lung, large intestine, liver, kidney channel, slightly poisonous.Heat-clearing and toxic substances removing, eliminating dampness and astringing sores, hemostasis analgesic therapy, dissipating blood stasis for subsidence of swelling.For pneumonia, over-strained hemoptysis, hemorrhoidal hemorrhage, traumatic injury, toxic swelling, water hygral expansion, ulcer does not close up for a long time." conventional Chinese herbal medicine formula " carries: " hemostasis of bringing down a fever, reducing swelling and alleviating pain.Control lung-heat to spit blood, abscess, festers, wound disunion of a specified duration.”
Hemlock chervil: bitter in the mouth, pungent, slightly warm in nature; Return spleen, large intestine channel, slightly poisonous.Promoting blood circulation and detumescence, convergence parasite killing.For chronic diarrhea, ascariasis, carbuncle sore does not close up for a long time, trichomonas vaginitis.
Radix indigoferae stachyoidis: sweet in the mouth, hardship, warm in nature; Return liver, kidney, large intestine channel.Tonify deficiency, invigorates blood circulation, Gu de-.For metrorrhagia, chronic dysentery, traumatic injury, rheumatism, ulcer does not close up for a long time." Yunnan Chinese herbal medicine " carries: " promoting blood circulation and stopping pain, relaxing muscles and tendons and activating QI and blood in the collateral.Control metrorrhagia, traumatic injury, rheumatism, liver cirrhosis, infantile malnutrition, dysentery.”
Radix seu Caulis Parthenocissi tricuspidatae: acrid in the mouth, micro-puckery, warm in nature; Return Liver Channel.Wind-expelling pain-stopping, promoting blood circulation to remove obstruction in the collateral.For rheumatic arthralgia, apoplexy and hemiplegia, migraine and general headache, puerperal blood stasis, the raw caking of abdomen, traumatic injury, carbuncle sore tumefacting virus, ulcer being unable to heal." Zhejiang conventional medical herbs among the people " carries: " wind-damp dispelling, the meridian dredging, hemostasis.”
Fructus Ilicis Purpureae: bitter in the mouth, sweet, cool in nature; Return liver, kidney channel.Invigorating the liver and kidney, curing rheumatism, arresting bleeding and healing up ulcer.For early whitening of beard and hair, wind shows arthralgia pain, digestive ulcerative bleeding, hemorrhoid, ulcer being unable to heal.
Catechu: bitter in the mouth, puckery, cold nature; Return lung meridian.Removing heat-phlegm, sore is stopped blooding.For cough due to lung-heat, diarrhoea, infantile dyspepsia, skin infection does not close up for a long time, skin eczema, aphtha, tonsillitis.
Membrana Follicularis ovi: sweet in the mouth, light, warm in nature.Nourishing YIN and clearing away lung-heat, sore removing nebula, synthetism.For coughing asthma outward, pharyngalgia aphonia, lymphoid tuberculosis; Ulcer being unable to heal; The raw cataracta of order, the vertigo, trauma fracture." classifying herbal " carries: " control infantile convulsion belly pain; Forge and grind painting skin ulcer, rawhide.”
Folium pterocaryae stenopterae: acrid in the mouth, hardship, warm in nature, poisonous; Return lung, Liver Channel.Wind-expelling pain-stopping, killing parasites for relieving itching, removing toxic substances sore.For rheumatic arthralgia, knee-joint pain, vagina wound, ulcer being unable to heal; Cough and asthma." Traditional Chinese Medicine in Sichuan will " carries: " parasite killing, removing toxic substances.Be coated with burn and skin ulcer, only toothache for a long time.”
Ramulus et Folium Adinae Piluliferae: bitter in the mouth, property is put down.Clearing away heat-damp and promoting diuresis, repercussive analgesic therapy, hemostasia and promoting granulation.For dysentery, enteritis, damp and hot edema, carbuncle sore tumefacting virus, eczema, rotten foot, ulcer being unable to heal, wound hemorrhage." Luchuan book on Chinese herbal medicine " carries: " eliminating inflammation and expelling toxin removing the necrotic tissue.Control skin infections poison, carbuncle sore ulceration.”
Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is put down; Return liver, kidney channel.Dissipating blood stasis blood, subduing inflammation.For gonorrhea hematuria, amenorrhea lump in the abdomen, difficult labour, postnatal blood stasis is suffered from abdominal pain, sore throat, carbuncle, traumatic injury." detailed outline " carries: " control chronic malaria cold and heat, five types of stranguria hematuria, pains in the penis, dysentery, sore throat, aphtha, toothache, carbuncle malignant boil, traumatics fracture.”
Herba Incarvilleae sinensis: bitter in the mouth, sweet, warm in nature; Return liver,spleen,kidney warp.Wind-damp dispelling, removing toxic substances parasite killing.For aphtha, gums festers, inflammation of external auditory meatus, eczema, scabies, trichomonal vaginitis.
Medulla Junci: sweet in the mouth, light, cold nature; GUIXIN, lung, small intestine meridian.Clearing away heart-fire, diuresis.For vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue." the conventional Chinese herbal medicine handbook in the north " carries: " heat clearing and tranquillizing, relieving stranguria by diuresis.”
Crusta Bombycis ovum: sweet in the mouth, property is put down; Return liver, heart channel.Hemostasis, dysentery relieving, removing toxic substances and promoting subsidence of swelling.For hematemesis and epistaxis, metrorrhagia, perianal abscess hematochezia, dysentery, swelling throat numbness, ulcerative gingivitis aphtha.
Folium Pleioblasti: sweet in the mouth, light, cold in nature; Return liver, the heart, lung meridian.Clearing heat and relieving fidgetness, diuresis of quenching one's thirst.Thirsty for fever and irritability, aphtha of the mouth and tongue, oliguria yellow skin." not Lu " carries: " treat aphtha, ophthalmalgia, improving eyesight, sharp nine orifices.”
The present invention compared with prior art, has following beneficial effect:
The Chinese crude drug prescription of the selected heat-clearing and toxic substances removing of Chinese medicine preparation of the present invention, sore hemostasis, anti-inflammation detumescence, promoting blood circulation and stopping pain is concocted, compatibility is suitable, there is effect of promoting blood circulation and detumescence, hemostasia and promoting granulation, clearing heat and relieving fidgetness, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, there are fabulous alleviation and therapeutic effect to recurrent oral ulceration, are suitable for recurrent oral ulceration clinical treatment and nursing is applied.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) Radix Cynanchi Auriculati, hemlock chervil, Radix indigoferae stachyoidis, Ramulus et Folium Adinae Piluliferae and Radix Achyranthis Bidentatae are put decontamination, be placed in container, add the distilled water of 8 ~ 10 times amount, soak after 4 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 1 ~ 3 hour, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
(2) get Herba Gynurae bicoloris, catechu and Crusta Bombycis ovum decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) Herba Lycopodii serrati, Radix seu Caulis Parthenocissi tricuspidatae, Membrana Follicularis ovi and Herba Incarvilleae sinensis are stir-fried with high heat for several times, surface uniform sprays yellow wine, pulverizes, grind into powder after fried dry, crosses 180 order fine powders, for subsequent use;
(4) getting Fructus Ilicis Purpureae, Folium pterocaryae stenopterae, Medulla Junci and Folium Pleioblasti saline mixes thoroughly vexed, and with the micro-stir-fry of little fire, taking-up is dried, and is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(5) by the filtrate of step (1) gained, mix with the fine powder of step (4) gained with step (2), step (3), make buccal tablet, be the Chinese medicine preparation for the treatment of recurrent oral ulceration of the present invention.
Usage and dosage: oral, every day 3 times, the morning, noon and afternoon, respectively once each 15 days was a course for the treatment of, and usual 2 ~ 5 courses for the treatment of are effective, and severe patient is followed the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
Select the routine clinical observation of Blood of Patients with Recurrent Oral 300 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random, treatment group 150 example, wherein male 75 example, women 75 example, 9 ~ 52 years old age, 25 years old mean age, the course of disease 3 days ~ 60 days, average 10 days.Matched group 150 example, wherein male 72 example, women 78 example, 12 ~ 45 years old age, 28 years old mean age, the course of disease 1 day ~ 36 days, average 7 days.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes Chinese medicine preparation of the present invention, oral, every day 3 times, and the morning, noon and afternoon, respectively once each 15 days was a course for the treatment of, usual 2 ~ 5 onsets course for the treatment of, and severe patient is followed the doctor's advice the meal with wine amount of adding.
Matched group patient is coated with gentamycin: dip ulcer surface in injection liquid of gentamicin dab oral cavity with disinfecting cotton swab, repaste once after several minutes, every day 4 times, and namely three after the meal and before sleeping, and coats medicinal liquid after gargling.
3, efficacy determination:
(1) cure: oral cavity bleeding blister, mouth burning tongue, oral mucosa fills the air congested grade for transference cure; The activity of mouth tongue is freely, in high spirits.
(2) effective: above-mentioned symptom is alleviated to some extent, and the activity of mouth tongue is freely, in high spirits.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 107 examples, effective 29 examples, invalid 14 examples, cure rate 71.3%, total effective rate 90.7%.
84 examples are cured, effective 34 examples, invalid 32 examples, cure rate 56%, total effective rate 78.6% in matched group.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, tight ××, man, 10 years old, student, people from Chengdu, Sichuan.Patient suffers from oral ulcer, cries and screams more than, cannot normally take food.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom is obviously alleviated, and after continuing to take 3 courses for the treatment of, mouth burning tongue, oral mucosa fills the air congested grade for transference cure, and activity freely.Follow up a case by regular visits to and do not recur so far.
2, golden ××, man, 17 years old, student, people from Xining, Qinghai.Patient's oral mucosa is extensively congested, dry mouth and parching tongue, and two cheeks are red and swollen, rotten to the corn, are diagnosed as recurrent oral ulceration.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom is clearly better, and after continuing to strengthen 2 courses for the treatment of of treatment, oral cavity function recovers normal, and activity freely.Follow up a case by regular visits to and do not recur so far.
3, Wei ××, female, 21 years old, student, the new village people in Hebei.There is aphtha, dysphoria and insomnia on the right side of buccal in patient oral cavity, complexion is sent out red, detests hydraulic fluid port greasy, and slightly unsatisfactory i.e. anger, red tongue, yellow fur is thick, is diagnosed as recurrent oral ulceration.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, and after continuing to take 3 courses for the treatment of, transference cure, activity freely.Follow up a case by regular visits to not recurrence.
4, pottery ××, female, 28 years old, Enterprise Staff, ShaoXing,ZheJiang people.Mucosa many places ulcer in patient's mouth, successively once fails to cure at many hospital therapies, and recurrence often increases the weight of, and have impact on work and life.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, symptom disappears completely, and freely, livelihood restoration is normal in activity.Follow up a case by regular visits to and do not recur so far.
5, Rhizoma Zingiberis Recens ××, female, 35 years old, trainer, Gansu the Jiayu Pass people.Patient oral cavity two cheek erosion, pain, dry mouth and parching tongue, oral mucosa is extensively congested, and two cheek posterior segment large area present greyish white ring-like netted, wax sample disease damage and companion is red and swollen, rotten to the corn, pus tongue and sepage, attaches most importance to left side.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom takes a turn for the better, after continuing to take 2 courses for the treatment of, activity freely, not recurrence.
6, relative ××, man, 46 years old, peasant, people from Jingmen, Hubei.Respectively there is aphtha, dysphoria and insomnia on the right side of buccal, patient oral cavity and the both sides of tongue, complexion is sent out red, self-induction palpitating speed, and bitter taste lack of appetite, detests hydraulic fluid port greasy, slightly unsatisfactory i.e. anger, constipation with dry stool, red tongue, and yellow fur is thick, and arteries and veins flood is sliding.Take Chinese medicine preparation of the present invention, after 2 courses for the treatment of, symptom obviously alleviates, and after continuing to take 2 courses for the treatment of, physical recovery is normal.
Claims (5)
1. treat a Chinese medicine preparation for recurrent oral ulceration, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Cynanchi Auriculati 62 ~ 92 parts of Herba Gynurae bicoloris 59 ~ 89 parts of Herba Lycopodii serratis 57 ~ 87 parts of hemlock chervils 55 ~ 85 parts
Radix indigoferae stachyoidis 52 ~ 82 portions of Radix seu Caulis Parthenocissi tricuspidataes 47 ~ 77 parts of Fructus Ilicis Purpureae 44 ~ 74 share tea 42 ~ 72 parts
Membrana Follicularis ovi 40 ~ 70 parts of Folium pterocaryae stenopteraes 37 ~ 67 parts of Ramulus et Folium Adinae Piluliferaes 35 ~ 65 parts of Radix Achyranthis Bidentataes 33 ~ 63 parts
Herba Incarvilleae sinensis 32 ~ 62 portions of Medulla Juncies 28 ~ 58 parts of Crusta Bombycis ovums 27 ~ 57 parts of Folium Pleioblastis 22 ~ 52 parts.
2. a kind of Chinese medicine preparation for the treatment of recurrent oral ulceration according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Cynanchi Auriculati 84 parts of Herba Gynurae bicoloris 81 parts of Herba Lycopodii serratis 79 parts of hemlock chervils 77 parts
Radix indigoferae stachyoidis 74 portions of Radix seu Caulis Parthenocissi tricuspidataes 69 parts of Fructus Ilicis Purpureae 67 share tea 64 parts
Membrana Follicularis ovi 63 parts of Folium pterocaryae stenopteraes 59 parts of Ramulus et Folium Adinae Piluliferaes 57 parts of Radix Achyranthis Bidentataes 55 parts
Herba Incarvilleae sinensis 54 portions of Medulla Juncies 50 parts of Crusta Bombycis ovums 49 parts of Folium Pleioblastis 44 parts.
3. a kind of Chinese medicine preparation for the treatment of recurrent oral ulceration according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Cynanchi Auriculati 77 parts of Herba Gynurae bicoloris 74 parts of Herba Lycopodii serratis 72 parts of hemlock chervils 70 parts
Radix indigoferae stachyoidis 67 portions of Radix seu Caulis Parthenocissi tricuspidataes 62 parts of Fructus Ilicis Purpureae 60 share tea 57 parts
Membrana Follicularis ovi 56 parts of Folium pterocaryae stenopteraes 52 parts of Ramulus et Folium Adinae Piluliferaes 50 parts of Radix Achyranthis Bidentataes 48 parts
Herba Incarvilleae sinensis 47 portions of Medulla Juncies 43 parts of Crusta Bombycis ovums 42 parts of Folium Pleioblastis 37 parts.
4. a kind of Chinese medicine preparation for the treatment of recurrent oral ulceration according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Radix Cynanchi Auriculati 70 parts of Herba Gynurae bicoloris 66 parts of Herba Lycopodii serratis 65 parts of hemlock chervils 63 parts
Radix indigoferae stachyoidis 60 portions of Radix seu Caulis Parthenocissi tricuspidataes 55 parts of Fructus Ilicis Purpureae 52 share tea 50 parts
Membrana Follicularis ovi 46 parts of Folium pterocaryae stenopteraes 45 parts of Ramulus et Folium Adinae Piluliferaes 43 parts of Radix Achyranthis Bidentataes 41 parts
Herba Incarvilleae sinensis 40 portions of Medulla Juncies 35 parts of Crusta Bombycis ovums 35 parts of Folium Pleioblastis 30 parts.
5. a preparation method for the Chinese medicine preparation of the treatment recurrent oral ulceration as described in any one of Claims 1 to 4, is characterized in that: comprise following processing step:
(1) Radix Cynanchi Auriculati, hemlock chervil, Radix indigoferae stachyoidis, Ramulus et Folium Adinae Piluliferae and Radix Achyranthis Bidentatae are put decontamination, be placed in container, add the distilled water of 8 ~ 10 times amount, soak after 4 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 1 ~ 3 hour, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, for subsequent use;
(2) get Herba Gynurae bicoloris, catechu and Crusta Bombycis ovum decontamination, microwave drying, smashs to pieces, is placed in mortar and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) Herba Lycopodii serrati, Radix seu Caulis Parthenocissi tricuspidatae, Membrana Follicularis ovi and Herba Incarvilleae sinensis are stir-fried with high heat for several times, surface uniform sprays yellow wine, pulverizes, grind into powder after fried dry, crosses 180 order fine powders, for subsequent use;
(4) getting Fructus Ilicis Purpureae, Folium pterocaryae stenopterae, Medulla Junci and Folium Pleioblasti saline mixes thoroughly vexed, and with the micro-stir-fry of little fire, taking-up is dried, and is placed in mortar and grinds into powder, crosses 200 order fine powders, for subsequent use;
(5) by the filtrate of step (1) gained, mix with the fine powder of step (4) gained with step (2), step (3), make buccal tablet, be the Chinese medicine preparation of described treatment recurrent oral ulceration.
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| CN102139081A (en) * | 2011-03-11 | 2011-08-03 | 中国人民解放军总医院 | Chinese medicinal composition and preparation for treating recurrent oral ulcer and preparation method thereof |
| CN103223059A (en) * | 2013-03-22 | 2013-07-31 | 孙秀娟 | Traditional Chinese medicine for treating recurrent oral ulcer |
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| CN102139081A (en) * | 2011-03-11 | 2011-08-03 | 中国人民解放军总医院 | Chinese medicinal composition and preparation for treating recurrent oral ulcer and preparation method thereof |
| CN103223059A (en) * | 2013-03-22 | 2013-07-31 | 孙秀娟 | Traditional Chinese medicine for treating recurrent oral ulcer |
Non-Patent Citations (2)
| Title |
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| 中医药治疗复发性口腔溃疡研究近况;王慈等;《四川中医》;20121231;第30卷(第12期);149-151 * |
| 复发性口腔溃疡的临床诊治探析;李秀荣;《吉林医学》;20140131;第35卷(第1期);59-60 * |
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