CN103721028A - Medicament for treating angina pectoris and preparation method thereof - Google Patents
Medicament for treating angina pectoris and preparation method thereof Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicament for treating angina pectoris and a preparation method thereof. The effective ingredients of the medicament are prepared from the following raw materials: lily, caulis clematidis armandii, rhizoma ligustici wallichii, aconitum kusnezoffii, flat-stemmed tetrastigma, setose thistle, radix cudramiae, cortex moutan, tree-of-heaven barks, bunge corydalis herbs, rhizoma paridis, roots of manyflower glorybower, saposhnicovia divaricata, leaves of ringworm senna, coconut and longstamen onion bulbs. The medicament disclosed by the invention is prepared from appropriately compatible traditional Chinese medicinal materials, has the effects of strengthening the heart and protecting the liver, and warmly invigorating the spleen and the stomach, can improve body immunity, regulate lipid metabolism, and promote heart function recovery, is distinct in curative effect and safe, has no toxic or side effect, and can be widely used in the clinical treatment of angina pectoris.
Description
Technical field
The present invention relates to western pharmaceutical field, relate in particular to a kind of anginal medicine and preparation method for the treatment of.
Background technology
Angina pectoris refers to because coronary atherosclerosis causes coronary insufficiency, the temporary transient ischemia of cardiac muscle and anoxia be caused take one group of syndrome that precordialgia is main clinical manifestation, its feature is paroxysmal shirtfront squeezing property pain perception, can be with other symptoms, pain is mainly positioned at breastbone rear portion, can be radiated to pareordia and left upper extremity, often betide work or when excited, each outbreak 3～5min, can a few days once, also can one day for several times, have a rest or with disappearing after nitrate preparations.Coronary heart disease is ascendant trend year by year at the sickness rate of China at present, and the people's Health and Living in serious harm, so the knowledge of universal publicity coronary heart disease actively prevents that coronary heart disease from being is significant for the health that improves the people effectively.
What coronary heart disease incidence rate was maximum is angina pectoris, comprises stability and unstable angina pectoris, and wherein stable angina pectoris belongs to the light-dutyest coronary heart disease.
Anginal main pathological change is coronary atherosclerosis in various degree.Think that at present the risk factor of the coronary atherosclerosis that causes has metabolism disorder of blood lipid, hypertension, diabetes, smoking, obesity, hyperuricemia hyperfibrinogenemia, inherited genetic factors etc.In addition male, old age, do not like that sporter is multiple.Wherein first five items is high at China's sickness rate, impact is serious, is the object of our major control.
At present, the medicine that supply patient with angina pectoris is taken is more, as SUXIAO JIUXIN WAN, Radix Salviae Miltiorrhizae Tabellae etc., although when this class medicine has certain curative effect in treatment angina pectoris, can not eradicate misery that can only respite patient, after drug effect, patient can continue to bear affliction.How fundamentally to treat angina pectoris and become a great difficult problem medically.
Summary of the invention
The object of this invention is to provide a kind of medicine and preparation method for the treatment of cardiovascular and cerebrovascular vessel; The suitable Chinese crude drug of choice of drug compatibility of the present invention, has the effect of heart tonifying hepatoprotective, warming and invigorating the spleen and stomach, can improve body's immunity, regulate blood lipid metabolism, promote cardiac function to recover, evident in efficacy, safe without toxic side effect, can be widely used in anginal clinical treatment.
For achieving the above object, being implemented as follows of technical scheme of the present invention:
Treat an anginal medicine, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Treat a preparation method for anginal medicine, comprise following processing step:
(1) add the water of 8 times of amounts after Bulbus Lilii, Caulis Clematidis Armandii, Cortex Ailanthi, Rhizoma Paridis, Radix Clerodenri Cyrtophylli and Cortex cocois radicis are mixed, extract 2～3 hours, filter taking liquid; In remaining residue, add again the water of 6 times of amounts, extract 1～2 hour, filter taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of relative density 1.10～1.15 under 60 ℃ of environment, standby;
(2) get Rhizoma Chuanxiong and clean, section is dried, and with yellow wine sprinkling evenly, putting and frying extremely micro-Jiao in pot is degree, and taking-up cools, and grinds into powder, crosses 160 order fine powders, standby;
(3) get Radix Aconiti Kusnezoffii and clean, dry, grind into powder, cross 180 order fine powders, standby;
(4) Caulis et Radix Tetrastigmatis Planicaulis, Radix Cudraniae and Cortex Moutan are ground into powder, crossed 200 order fine powders, standby.
(5) get Radix Cirsii Japonici, Herba Violae, Folium Cassiae Alatae and Bulbus Allii Macrostemonis and clean, strand juice, filters, and obtains juice standby;
(6) Radix Saposhnikoviae is cleaned to decontamination, section is dried, and is placed in pot interior slow fire and is fried to surface and is black, and taking-up is dried in the air cool, and be placed in mortar and grind into powder, mistake 240 order fine powders, standby.
(7) above-mentioned steps (1)～(6) prepared thick paste, fine powder and juice are mixed, make capsule, be the anginal medicine for the treatment of of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Bulbus Lilii: sweet in the mouth, micro-hardship, property is flat; Enter lung, the heart, gallbladder three warps.Nourishing the lung to arrest cough, clearing away heart-fire for tranquillization.Cure mainly lung expense chronic cough, cough and spit expectorant blood, after calentura, waste heat comes clearly, fidgets due to deficiency palpitation with fear, staring spells, beriberi edema.< < property of medicine opinion > > carries: " except spasm in the epigastrium, full, bitterly, control beriberi, heat syndrome cough is contrary.”
Caulis Clematidis Armandii: bitter in the mouth, light, cold in nature; GUIXIN, lung, small intestinal, urinary bladder channel.Clearing away heat and promoting diuresis, the stimulating milk secretion of stimulating the menstrual flow.For edema, gonorrhea, urinary obstruction, arthralgia, amenorrhea breast less, pathogenic fire reducing.< < Japan hanako materia medica > > carries: " relieving restlessness of feeling at ease, quenches the thirst and brings down a fever, and improve visual and auditory acuity is controlled nasal obstruction, logical small intestinal, and lower water, removing mass gathers clot, and furuncle is controlled in evacuation of pus, pain relieving." studies confirm that, this product has diuresis, and multiple pathomycete is had to inhibitory action.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature; Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for pacifying nerve, wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, rheumatic arthralgia.< < Japan hanako materia medica > > carries: " control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, and strengthening bone and muscle, adjusts many arteries and veins, and broken crux stagnated blood, supports fresh blood, puts on flesh.”
Radix Aconiti Kusnezoffii: acrid in the mouth, hardship, hot in nature, malicious greatly; GUIXIN, liver, spleen channel.Expelling wind and removing dampness, dispelling cold by warming the meridian, reducing swelling and alleviating pain.Cure mainly anemofrigid-damp arthralgia, arthralgia, wind syndrome of head headache, apoplectic dyscinesia, trusted subordinate's cold type of pain, colic of cold type is had a pain, traumatic injury, swelling and pain due to blood stasis, carbuncle of yin nature toxic swelling, narcotic analgesic.
Caulis et Radix Tetrastigmatis Planicaulis: sour in the mouth, puckery, warm in nature; GUIXIN, Liver Channel.The removing dampness of dispeling the wind, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly rheumatic arthralgia, lumbar muscle strain, apoplectic hemiplegia, traumatic injury.The conventional Chinese herbal medicine handbook > > of the < < of Guangzhou army carries: " dispeiling pathogenic wind and removing dampness.Treating rheumatic lumbago and skelalgia, hemiplegia, rheumatism of muscles pain.”
Radix Cirsii Japonici: sweet in the mouth, hardship, cool in nature, nontoxic; GUIXIN, Liver Channel.Cure mainly haematemesis, epistaxis, hematuria, stranguria with blood, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, acute appendicitis, carbuncle and ulcer, toxic swelling, furuncle.< < the southern regions of the Yunnan Province book on Chinese herbal medicine > >: " repercussive blood, tissue regeneration promoting blood, emesis blood, nose bleeding.Control children's's hematuria, the red hematochezia that collapses of married woman, the raw blood of mending all warps, the sore that disappears, loose scrofula tuberculosis, carbuncle sore not closing in for a long time person, granulation promoting evacuation of pus." experimentation proves, Radix Cirsii Japonici has more remarkable and lasting hypotensive activity function, and has antiinflammatory, hemostasis and recover liver function, promote the effect of liver cell regeneration; be applicable to acute calenture struvite hemorrhage; yellow cellulitis, hepatitis, the treatment of the diseases such as pyretic stranguria, hematuria.
Radix Cudraniae: lightly seasoned, micro-hardship, cool in nature.Dispelling wind and removing obstruction in the collateral, removing damp-heat, removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome, traumatic injury, yellow cellulitis, parotitis, pulmonary tuberculosis, gastric duodenal ulcer, stranguria with turbid discharge, distention of the abdomen caused by various parasites, amenorrhea, impairment caused by overstrain hemoptysis, treats carbuncle sore swollen.Modern medicine study confirmation, Radix Cudraniae root ethanol extraction has good anti-tubercle bacillus effect.
Cortex Moutan: bitter in the mouth, cold nature; GUIXIN, liver, kidney, lung meridian.Clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Cure mainly and send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, deficiency of YIN osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury, rheumatism pyretic arthralgia.< < Mingyi Bielu > > carries: " except seasonal epidemic pathogens headache, exopathogenic heat five kinds of over strain, consumptive disease head lumbago, wind is kept silent, insane disease." studies confirm that, Cortex Moutan all has potentiation to body fluid and cellular immunization.
Cortex Ailanthi: bitter in the mouth, puckery, cold in nature; Return stomach, large intestine, the heart, liver, spleen, lung meridian.Heat clearing and damp drying, astringing intestine to stop diarrhea, hemostasis leukorrhagia stopping, parasite killing.Cure mainly and have loose bowels, dysentery, has blood in stool, metrorrhagia, bleeding hemorrhoids, leukorrhagia, ascariasis, skin ulcer tinea.The modern Practical Chinese medicinal > of < < > carries: " married woman's metrorrhagia and postpartum hemorrhage, metritis, enteritis, bloody dysentery, enterorrhagia, bladder and urethra inflammation, the gonorrhea etc. controlled for oral administration, have that antiinflammatory, system are secreted, the merit of hemostasis; The illness of training the mind dysmenorrhoea and liver, spleen etc. again." modern medicine study confirms; Cortex Ailanthi decoct has obvious inhibitory action to shigella flexneri, Song's Shigella flexneri and escherichia coli; contained ailanthinone and Ramulus Et Folium Picrasmae have antitumor action, is used for clinically treating acute bacillary dysentery, amebic dysentery, has blood in stool, ulcer, ascariasis and cervical cancer.
Herba Violae: bitter in the mouth, cold in nature; GUIXIN, liver, spleen channel.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Cure mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.< < the southern regions of the Yunnan Province book on Chinese herbal medicine > > carries: " removing blood stasis is separated carbuncle mange, nine kinds of hemorrhoid, all sore diseases.”
Rhizoma Paridis: bitter in the mouth, cool in nature, mild toxicity; GUIXIN, liver, lung, stomach, large intestine channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, cool liver arresting convulsion.Cure mainly carbuncle sore tumefacting virus, pharyngeal swelling sore throat, acute mastitis, snake bite and insect sting, traumatic pain, liver-heat is twitched.Modern medicine study confirmation, Rhizoma Paridis has good result to the woman's galactostasis of managing property.
Radix Clerodenri Cyrtophylli: bitter in the mouth, cold in nature; GUIXIN, Liver Channel.Heat-clearing and toxic substances removing, removing heat from blood.Cure mainly encephalitis b, epidemic encephalitis, the high heat of flu, epidemic encephalitis, parotitis, heat in blood is sent out class, measles pneumonia, icteric tripe is scorching, diarrhea of heat type hematodiarrhoea, rheumatism pyretic arthralgia, headache, laryngopharynx swelling and pain, acute toothache, orchitis.The conventional Chinese herbal medicine handbook > > of the < < of Guangzhou army carries: " clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, dissipating blood stasis hemostasis.Control enteritis, bacillary dysentery, pharyngolaryngitis, tonsillitis, parotitis, cold, fever, gingiva bleeding gingival hemorrhage.”
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature; Return bladder, lung, spleen, Liver Channel.Expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.Cure mainly affection of exogenous wind-cold, headache general pain, rheumatic arthralgia, joint is ached, stomachache is had loose bowels, discharging fresh blood stool, tetanus, rubella pruritus, skin infection from the beginning of.< < Changsha medicine solution > > carries: " network of passing through, by wet excessive, gets round by bribery, and pain relieves the pain; relaxing muscles and tendons arteries and veins, stretches anxious twinly, and the podomere of living; play paralysis, hold back spontaneous perspiration, night sweat, breaks, metrorrhagia.”
Folium Cassiae Alatae: acrid in the mouth, hardship, cold in nature, tepor; GUIXIN, spleen channel.Parasite killing, antipruritic.Cure mainly neurodermatitis, psoriasis, eczema, skin pruritus, furuncle pus infections.< < Simao, Yunnan Chinese herbal medicine selects > > to carry: " parasite killing, antipruritic, control neurodermatitis, psoriasis, eczema, skin pruritus, the furuncle rash that swells.”
Cortex cocois radicis: sweet in the mouth, property are put down; Enter stomach, spleen, large intestine channel.Xu-tonic, QI invigorating is dispeled the wind, the infantile malnutrition that disappears parasite killing, nourishing, clearing away summer-heat quenches one's thirst.Cure mainly children's and wash worm, fasciolopsiasis buski, summer-heat class is thirsty, deficiency of body fluid thirsty.Modern medicine study confirmation, the suitable heating of Cortex cocois radicis or summer-heat weather, xerostomia eat when thirsty, and the suitable congestive heart failure person of Cortex cocois radicis is edible simultaneously.
Bulbus Allii Macrostemonis: acrid in the mouth, hardship, warm in nature; Return lung, the heart, stomach, large intestine channel.Activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.Cure mainly the thorough back of the body of obstruction of qi in the chest and cardialgia, breast gastral cavity painful abdominal mass is vexed, cough with asthma abundant expectoration, epigastric pain, let out after dysentery heavy, leucorrhea, furuncle carbuncle.< < detailed outline > > carries: " control SHAO YIN syndrome and faint and contrary let out dysentery, and thoracic obstruction twinge, the therapeutic method to keep the adverse QI flowing downwards blood that falls apart, antiabortive.Temperature compensation is supporing yang road.”
The present invention compared with prior art, has following beneficial effect:
The suitable Chinese crude drug of choice of drug compatibility of the present invention, has the effect of heart tonifying hepatoprotective, warming and invigorating the spleen and stomach, can improve body's immunity, regulate blood lipid metabolism, promote cardiac function to recover, evident in efficacy, safe without toxic side effect, can be widely used in anginal clinical treatment.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is done further and supplemented, but do not limit the present invention in any way.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
The preparation method of medicine of the present invention, is characterized in that: comprise following processing step:
(1) add the water of 8 times of amounts after Bulbus Lilii, Caulis Clematidis Armandii, Cortex Ailanthi, Rhizoma Paridis, Radix Clerodenri Cyrtophylli and Cortex cocois radicis are mixed, extract 2～3 hours, filter taking liquid; In remaining residue, add again the water of 6 times of amounts, extract 1～2 hour, filter taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of relative density 1.10～1.15 under 60 ℃ of environment, standby;
(2) get Rhizoma Chuanxiong and clean, section is dried, and with yellow wine sprinkling evenly, putting and frying extremely micro-Jiao in pot is degree, and taking-up cools, and grinds into powder, crosses 160 order fine powders, standby;
(3) get Radix Aconiti Kusnezoffii and clean, dry, grind into powder, cross 180 order fine powders, standby;
(4) Caulis et Radix Tetrastigmatis Planicaulis, Radix Cudraniae and Cortex Moutan are ground into powder, crossed 200 order fine powders, standby.
(5) get Radix Cirsii Japonici, Herba Violae, Folium Cassiae Alatae and Bulbus Allii Macrostemonis and clean, strand juice, filters, and obtains juice standby;
(6) Radix Saposhnikoviae is cleaned to decontamination, section is dried, and is placed in pot interior slow fire and is fried to surface and is black, and taking-up is dried in the air cool, and be placed in mortar and grind into powder, mistake 240 order fine powders, standby.
(7) above-mentioned steps (1)～(6) prepared thick paste, fine powder and juice are mixed, make capsule, be the anginal medicine for the treatment of of the present invention.
Usage and dosage: oral, every day 3 times, each 2, warm water delivery service after meal; Within 12 days, be 1 course for the treatment of, can cure 2～3 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of effective ingredient of the present invention forms and weight is:
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
The raw material of effective ingredient of the present invention forms and weight is:
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the anginal medicine for the treatment of, the routine clinical observation of patient with angina pectoris 152 that selection is made a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group 78 examples, wherein male's 40 examples at random, women's 38 examples, 40～71 years old age, 55.3 years old mean age, the shortest person of the course of disease 3 months, elder 5 years, average 2 years.Matched group 74 examples, male's 38 examples wherein, women's 36 examples, 41～70 years old age, 53.3 years old mean age, the shortest person of the course of disease 4 months, elder 6 years, average 3 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken medicine of the present invention, oral, every day 3 times, each 2, warm water delivery service after meal; Within 12 days, be 1 course for the treatment of, take continuously 2～3 courses for the treatment of, the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken SUXIAO JIUXIN WAN, and by specification or doctor's advice are taken, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
3, efficacy determination:
(1) cure: the transference cures such as chest pain, it is normal that internal metabolism recovers, and patient's body's immunity strengthens.
(2) take a turn for the better: the symptoms such as chest pain are alleviated to some extent, and immunologic function is recovered to some extent.
(3) invalid: clinical symptoms is unchanged.
4, result:
Select in the treatment group of medicine of the present invention, cure 48 examples, 26 examples that take a turn for the better, invalid 4 examples, cure rate 61.5%, total effective rate 94.9%.
In matched group, cure 21 examples, 21 examples that take a turn for the better, invalid 32 examples, cure rate 28.4%, total effective rate 56.8%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, Dong, female, 43 years old, people from Lvliang City, Shanxi.Patient is because of overworked processus aboralis sense ambition severe pain, and as thorn as strand, and with sensation of oppression over the chest with shortness of breath, nervous, activity more very.To our hospital, through Electrocardioscopy, be angina pectoris outbreak, take medicine of the present invention, to take after 1 course for the treatment of, symptom disappears substantially, takes after 2 courses for the treatment of, and symptom disappears completely, and normal ECG is followed up a case by regular visits to not recurrence in a year.
2, Xue, man, 56 years old, people from Huzhou, Zhejiang.During patient's morning exercises, prominent sense pareordia twinge, pain are drawn shoulder and are carried on the back and be ictal, certainly take SUXIAO JIUXIN WAN remission after approximately ten minutes, and rear recurrent number increases gradually.To our hospital, finding that there is property of Electrocardioscopy myocardial ischemia phenomenon, recommends through doctor, takes medicine of the present invention, take after 1 course for the treatment of, symptom is obviously improved, and takes after the 2nd course for the treatment of recovery from illness, general malaise transference cure, Electrocardioscopy is normal, follows up a case by regular visits to not recurrence in a year.
3, Cao, man, 70 years old, From Shandong Rizhao people.Patient is feeling of oppression and pain in the chest always, nervous cardiopalmus, and with the serious symptoms such as limbs fatigue.After by children, send into hospital admission, through Electrocardioscopy, be angina pectoris outbreak.Take multi-medicament all without positive effect, by doctor, recommend to take medicine of the present invention, take after 2 courses for the treatment of, symptom disappears substantially, fully recovers after taking 4 courses for the treatment of, follows up a case by regular visits to, so far recurrence.
Claims (5)
1. treat an anginal medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
28～58 parts of 33～58 parts of Radix Aconiti Kusnezoffiis of 33～63 parts of Rhizoma Chuanxiongs of 38～68 portions of Caulis Clematidis Armandiis of Bulbus Lilii
23～53 parts of 23～53 parts of Cortex Moutans of 28～53 parts of Radix Cudraniaes of 28～58 portions of Radix Cirsii Japonicis of Caulis et Radix Tetrastigmatis Planicaulis
18～43 parts of 18～43 parts of Radix Clerodenri Cyrtophyllis of 18～48 parts of Rhizoma Paridis of 23～48 portions of Herba Violaes of Cortex Ailanthi
8～33 parts of 13～38 parts of Bulbus Allii Macrostemonis of 13～43 portions of Cortex cocois radiciss of 18～48 parts of Folium Cassiae Alataes of Radix Saposhnikoviae.
2. a kind of anginal medicine for the treatment of according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
33～53 parts of 37～54 parts of Radix Aconiti Kusnezoffiis of 38～58 parts of Rhizoma Chuanxiongs of 43～63 portions of Caulis Clematidis Armandiis of Bulbus Lilii
28～48 parts of 28～48 parts of Cortex Moutans of 32～49 parts of Radix Cudraniaes of 33～53 portions of Radix Cirsii Japonicis of Caulis et Radix Tetrastigmatis Planicaulis
22～39 parts of 22～39 parts of Radix Clerodenri Cyrtophyllis of 23～43 parts of Rhizoma Paridis of 27～44 portions of Herba Violaes of Cortex Ailanthi
12～29 parts of 17～34 parts of Bulbus Allii Macrostemonis of 18～38 portions of Cortex cocois radiciss of 23～43 parts of Folium Cassiae Alataes of Radix Saposhnikoviae.
3. a kind of anginal medicine for the treatment of according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
38～48 parts of 41～50 parts of Radix Aconiti Kusnezoffiis of 43～53 parts of Rhizoma Chuanxiongs of 48～58 portions of Caulis Clematidis Armandiis of Bulbus Lilii
33～43 parts of 33～43 parts of Cortex Moutans of 36～45 parts of Radix Cudraniaes of 38～48 portions of Radix Cirsii Japonicis of Caulis et Radix Tetrastigmatis Planicaulis
26～35 parts of 26～35 parts of Radix Clerodenri Cyrtophyllis of 28～38 parts of Rhizoma Paridis of 31～40 portions of Herba Violaes of Cortex Ailanthi
16～26 parts of 21～30 parts of Bulbus Allii Macrostemonis of 23～33 portions of Cortex cocois radiciss of 28～38 parts of Folium Cassiae Alataes of Radix Saposhnikoviae.
4. a kind of anginal medicine for the treatment of according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
43 parts of 45 parts of Radix Aconiti Kusnezoffiis of 48 parts of Rhizoma Chuanxiongs of 53 portions of Caulis Clematidis Armandiis of Bulbus Lilii
38 parts of 38 parts of Cortex Moutans of 40 parts of Radix Cudraniaes of 43 portions of Radix Cirsii Japonicis of Caulis et Radix Tetrastigmatis Planicaulis
30 parts of 30 parts of Radix Clerodenri Cyrtophyllis of 33 parts of Rhizoma Paridis of 36 portions of Herba Violaes of Cortex Ailanthi
20 parts of 26 parts of Bulbus Allii Macrostemonis of 28 portions of Cortex cocois radiciss of 33 parts of Folium Cassiae Alataes of Radix Saposhnikoviae.
5. as described in claim 1～4 any one, treat a preparation method for anginal medicine, it is characterized in that: comprise following processing step:
(1) add the water of 8 times of amounts after Bulbus Lilii, Caulis Clematidis Armandii, Cortex Ailanthi, Rhizoma Paridis, Radix Clerodenri Cyrtophylli and Cortex cocois radicis are mixed, extract 2～3 hours, filter taking liquid; In remaining residue, add again the water of 6 times of amounts, extract 1～2 hour, filter taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of relative density 1.10～1.15 under 60 ℃ of environment, standby;
(2) get Rhizoma Chuanxiong and clean, section is dried, and with yellow wine sprinkling evenly, putting and frying extremely micro-Jiao in pot is degree, and taking-up cools, and grinds into powder, crosses 160 order fine powders, standby;
(3) get Radix Aconiti Kusnezoffii and clean, dry, grind into powder, cross 180 order fine powders, standby;
(4) Caulis et Radix Tetrastigmatis Planicaulis, Radix Cudraniae and Cortex Moutan are ground into powder, crossed 200 order fine powders, standby;
(5) get Radix Cirsii Japonici, Herba Violae, Folium Cassiae Alatae and Bulbus Allii Macrostemonis and clean, strand juice, filters, and obtains juice standby;
(6) Radix Saposhnikoviae is cleaned to decontamination, section is dried, and is placed in pot interior slow fire and is fried to surface and is black, and taking-up is dried in the air cool, and be placed in mortar and grind into powder, mistake 240 order fine powders, standby;
(7) above-mentioned steps (1)～(6) prepared thick paste, fine powder and juice are mixed, make capsule, be the anginal medicine for the treatment of of the present invention.
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| CN1872329A (en) * | 2005-06-03 | 2006-12-06 | 天津天士力制药股份有限公司 | Application of medication composition of containing giant gen-seng in preparing medicine for treating insufficiency of blood supply for brain |
| CN1943769A (en) * | 2006-10-17 | 2007-04-11 | 吴鹏 | An external pharmaceutical for treatment of arrhythmia, coronary heart disease and angina pectoris |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1872329A (en) * | 2005-06-03 | 2006-12-06 | 天津天士力制药股份有限公司 | Application of medication composition of containing giant gen-seng in preparing medicine for treating insufficiency of blood supply for brain |
| CN1943769A (en) * | 2006-10-17 | 2007-04-11 | 吴鹏 | An external pharmaceutical for treatment of arrhythmia, coronary heart disease and angina pectoris |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104522213A (en) * | 2015-01-15 | 2015-04-22 | 山东省农业科学院畜牧兽医研究所 | Tea suitable for three-high crowds and making method of tea suitable for three-high crowds |
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