CN103721028B - One treats anginal medicine and preparation method - Google Patents

One treats anginal medicine and preparation method Download PDF

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CN103721028B
CN103721028B CN201410032172.7A CN201410032172A CN103721028B CN 103721028 B CN103721028 B CN 103721028B CN 201410032172 A CN201410032172 A CN 201410032172A CN 103721028 B CN103721028 B CN 103721028B
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radix
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cortex
caulis
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CN103721028A (en
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李晓霞
杨国堂
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Guangdong kangqili pharmaceutical Limited by Share Ltd
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李晓霞
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Abstract

The invention discloses one and treat anginal medicine and preparation method, the raw material making described effective ingredient consists of Bulbus Lilii, Caulis Clematidis Armandii, Rhizoma Chuanxiong, Radix Aconiti Kusnezoffii, Caulis et Radix Tetrastigmatis Planicaulis, Radix Cirsii Japonici, Radix Cudraniae, Cortex Moutan, Cortex Ailanthi, Herba Violae, Rhizoma Paridis, Radix Clerodenri Cyrtophylli, Radix Saposhnikoviae, Folium Cassiae Alatae, Cortex cocois radicis and Bulbus Allii Macrostemonis and is prepared from; The Chinese crude drug that choice of drug compatibility of the present invention is suitable, has effect of heart tonifying hepatoprotective, warming and invigorating the spleen and stomach, can improve body's immunity, adjusting blood lipid metabolism, promotes that cardiac function recovers, evident in efficacy, safe without toxic side effect, can be widely used in anginal clinical treatment.

Description

One treats anginal medicine and preparation method
Technical field
The present invention relates to western pharmaceutical field, particularly relate to one and treat anginal medicine and preparation method.
Background technology
Angina pectoris refers to because coronary atherosclerosis causes coronary insufficiency, caused by cardiac muscle ischemia and anoxia take precordialgia as one group of syndrome of main clinical manifestation, its feature is paroxysmal shirtfront squeezing property pain perception, can with other symptoms, pain is mainly positioned at breastbone rear portion, pareordia and left upper extremity can be radiated to, often betide work or excited time, each outbreak 3 ~ 5min, can a few days once, also can one day for several times, have a rest or disappear with after nitrate preparations.Coronary heart disease at present at the sickness rate of China in ascendant trend year by year, the Health and Living of the people in serious harm, so the knowledge of universal publicity coronary heart disease, actively effectively prevents coronary heart disease from being be significant for the health improving the people.
What coronary heart disease incidence rate was maximum is angina pectoris, and comprise stability and unstable angina pectoris, wherein stable angina pectoris belongs to the light-dutyest coronary heart disease.
Anginal main pathological change is coronary atherosclerosis in various degree.Think that the risk factor of the coronary atherosclerosis caused has metabolism disorder of blood lipid, hypertension, diabetes, smoking, obesity, hyperuricemia hyperfibrinogenemia, inherited genetic factors etc. at present.In addition male, old age, do not like that sporter is multiple.Wherein first five items is high at China's sickness rate, impact is serious, is the object of our major control.
At present, the medicine that supply patient with angina pectoris is taken is more, as SUXIAO JIUXIN WAN, Radix Salviae Miltiorrhizae Tabellae etc., although when this kind of medicine has certain curative effect in treatment angina pectoris, can not eradicate, can only the misery of respite patient, after drug effect, patient can continue to bear affliction.How fundamentally treatment angina pectoris has become a great difficult problem medically.
Summary of the invention
The object of this invention is to provide a kind of medicine and preparation method for the treatment of cardiovascular and cerebrovascular vessel; The Chinese crude drug that choice of drug compatibility of the present invention is suitable, has effect of heart tonifying hepatoprotective, warming and invigorating the spleen and stomach, can improve body's immunity, adjusting blood lipid metabolism, promotes that cardiac function recovers, evident in efficacy, safe without toxic side effect, can be widely used in anginal clinical treatment.
For achieving the above object, being implemented as follows of technical scheme of the present invention:
One treats anginal medicine, and raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Treat a preparation method for anginal medicine, comprise following processing step:
(1) by adding the water of 8 times amount after Bulbus Lilii, Caulis Clematidis Armandii, Cortex Ailanthi, Rhizoma Paridis, Radix Clerodenri Cyrtophylli and Cortex cocois radicis mixing, extracting 2 ~ 3 hours, filtering, taking liquid; In remaining residue, add the water of 6 times amount again, extract 1 ~ 2 hour, filter, taking liquid; Merge twice medicinal liquid, be condensed into the thick paste of relative density 1.10 ~ 1.15 under 60 DEG C of environment, for subsequent use;
(2) get Rhizoma Chuanxiong to clean, section is dried, and sprays evenly with yellow wine, and putting stir-fry in pot is degree to micro-Jiao, and taking-up cools, and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) get Radix Aconiti Kusnezoffii to clean, dry, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Caulis et Radix Tetrastigmatis Planicaulis, Radix Cudraniae and Cortex Moutan are ground into powder, cross 200 order fine powders, for subsequent use.
(5) get Radix Cirsii Japonici, Herba Violae, Folium Cassiae Alatae and Bulbus Allii Macrostemonis to clean, strand juice, filters, obtains juice for subsequent use;
(6) Radix Saposhnikoviae is cleaned decontamination, section is dried, and be placed in slow fire in pot and be fried to surface in black, taking-up is dried in the air cool, is placed in mortar and grinds into powder, crosses 240 order fine powders, for subsequent use.
(7) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (6), make capsule, be the anginal medicine for the treatment of of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Bulbus Lilii: sweet in the mouth, micro-hardship, property is put down; Enter lung, the heart, gallbladder three warp.Nourishing the lung to arrest cough, clearing away heart-fire for tranquillization.Cure mainly lung expense chronic cough, cough and spit expectorant blood, after calentura, waste heat comes clear, and fidgets due to deficiency is palpitated with fear, staring spells, beriberi edema." property of medicine opinion " carries: " except spasm in the epigastrium, completely, bitterly, control beriberi, heat syndrome cough is inverse.”
Caulis Clematidis Armandii: bitter in the mouth, light, cold in nature; GUIXIN, lung, small intestinal, urinary bladder channel.Clearing away heat and promoting diuresis, stimulating milk secretion of stimulating the menstrual flow.For edema, gonorrhea, urinary obstruction, arthralgia, amenorrhea breast less, pathogenic fire reducing." Japan hanako materia medica " carries: " relieving restlessness of feeling at ease, quenches the thirst and bring down a fever, and improve visual and auditory acuity controls nasal obstruction, and logical small intestinal, lower water, removing mass gathers clot, evacuation of pus, controls furuncle, pain relieving." research confirmation, this product has diuresis, has inhibitory action to multiple pathomycete.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature; Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For pacifying nerve, wind syndrome of head is had a headache, and lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, rheumatic arthralgia." Japan hanako materia medica " carries: " control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, strengthening bone and muscle, adjusts many arteries and veins, and broken crux stagnated blood, supports fresh blood, put on flesh.”
Radix Aconiti Kusnezoffii: acrid in the mouth, hardship, hot in nature, poison greatly; GUIXIN, liver, spleen channel.Expelling wind and removing dampness, dispelling cold by warming the meridian, reducing swelling and alleviating pain.Cure mainly anemofrigid-damp arthralgia, arthralgia, wind syndrome of head is had a headache, and apoplectic dyscinesia, trusted subordinate's cold type of pain, colic of cold type is had a pain, traumatic injury, swelling and pain due to blood stasis, carbuncle of yin nature toxic swelling, narcotic analgesic.
Caulis et Radix Tetrastigmatis Planicaulis: sour in the mouth, puckery, warm in nature; GUIXIN, Liver Channel.To dispel the wind removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly rheumatic arthralgia, lumbar muscle strain, apoplectic hemiplegia, traumatic injury.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " dispeiling pathogenic wind and removing dampness.Treating rheumatic lumbago and skelalgia, hemiplegia, rheumatism of muscles pain.”
Radix Cirsii Japonici: sweet in the mouth, hardship, cool in nature, nontoxic; GUIXIN, Liver Channel.Cure mainly haematemesis, epistaxis, hematuria, stranguria with blood, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, acute appendicitis, carbuncle and ulcer, toxic swelling, furuncle." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " repercussive blood, tissue regeneration promoting blood, emesis blood, nose bleeding.Control children's's hematuria, married woman is red collapses hematochezia, the raw blood mending all warps, and disappear sore, loose scrofula tuberculosis, carbuncle sore not closing in for a long time person, granulation promoting evacuation of pus." experimentation proves, Radix Cirsii Japonici has more remarkable and lasting hypotensive activity function, and has antiinflammatory, hemostasis and recover liver function, promote the effect of liver cell regeneration; be applicable to acute calenture struvite hemorrhage; yellow cellulitis, hepatitis, the treatment of the disease such as pyretic stranguria, hematuria.
Radix Cudraniae: lightly seasoned, micro-hardship, cool in nature.Dispelling wind and removing obstruction in the collateral, removing damp-heat, removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome, traumatic injury, yellow cellulitis, parotitis, pulmonary tuberculosis, gastric duodenal ulcer, stranguria with turbid discharge, distention of the abdomen caused by various parasites, amenorrhea, impairment caused by overstrain hemoptysis, treats carbuncle sore and swells.Modern medicine study confirms, Radix Cudraniae root ethanol extraction has good anti-tubercle bacillus effect.
Cortex Moutan: bitter in the mouth, cold nature; GUIXIN, liver, kidney, lung meridian.Clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Cure mainly and send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, and carbuncle sore tumefacting virus, falls and flutter the pain of injury, beriberoid pyretic arthralgia." Mingyi Bielu " carries: " except seasonal epidemic pathogens headache, exopathogenic heat five kinds of over strain, consumptive disease head lumbago, wind is kept silent, insane disease." research confirmation, Cortex Moutan all has potentiation to body fluid and cellular immunization.
Cortex Ailanthi: bitter in the mouth, puckery, cold in nature; Return stomach, large intestine, the heart, liver, spleen, lung meridian.Heat clearing and damp drying, astringing intestine to stop diarrhea, hemostasis leukorrhagia stopping, parasite killing.Cure mainly and have loose bowels, dysentery, have blood in stool, metrorrhagia, bleeding hemorrhoids, leukorrhagia, ascariasis, skin ulcer tinea." modern Practical Chinese medicinal " carries: " for oral administration control married woman's metrorrhagia and postpartum hemorrhage, metritis, enteritis, bloody dysentery, enterorrhagia, bladder and urinary tract inflammation, gonorrhea etc., have antiinflammatory, system is secreted, the merit of hemostasis; The illness of training the mind dysmenorrhoea and liver, spleen etc. again." modern medicine study confirm; Cortex Ailanthi decoct has obvious inhibitory action to shigella flexneri, S. sonnei and escherichia coli; contained ailanthinone and Ramulus Et Folium Picrasmae have antitumor action, be used for clinically treatment acute bacillary dysentery, amebic dysentery, have blood in stool, ulcer, ascariasis and cervical cancer.
Herba Violae: bitter in the mouth, cold in nature; GUIXIN, liver, spleen channel.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Cure mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " removing blood stasis separates carbuncle mange, nine kinds of hemorrhoid, all sore diseases.”
Rhizoma Paridis: bitter in the mouth, cool in nature, mild toxicity; GUIXIN, liver, lung, stomach, large intestine channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, cool liver arresting convulsion.Cure mainly carbuncle sore tumefacting virus, pharyngeal swelling sore throat, acute mastitis, snake bite and insect sting, traumatic pain, liver-heat is twitched.Modern medicine study confirms, Rhizoma Paridis has good result to woman's galactostasis of managing property.
Radix Clerodenri Cyrtophylli: bitter in the mouth, cold in nature; GUIXIN, Liver Channel.Heat-clearing and toxic substances removing, removing heat from blood.Cure mainly encephalitis b, epidemic encephalitis, the high heat of flu, epidemic encephalitis, parotitis, heat in blood sends out class, measles pneumonia, and icteric tripe is scorching, diarrhea of heat type hematodiarrhoea, beriberoid pyretic arthralgia, headache, laryngopharynx swelling and pain, acute toothache, orchitis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " dissipating blood stasis stops blooding for clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body.Control enteritis, bacillary dysentery, pharyngolaryngitis, tonsillitis, parotitis, cold, fever, gingiva bleeding gingival hemorrhage.”
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature; Return bladder, lung, spleen, Liver Channel.Expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.Cure mainly affection of exogenous wind-cold, headache general pain, rheumatic arthralgia, joint is ached, and stomachache is had loose bowels, discharging fresh blood stool, tetanus, rubella pruritus, skin infection from the beginning of." Changsha medicine solution " carries: " network of passing through, by wet excessive, gets round by bribery, and relieve the pain pain, relaxing muscles and tendons arteries and veins, stretches anxious twin, podomere of living, and plays paralysis, holds back spontaneous perspiration, night sweat, break, metrorrhagia.”
Folium Cassiae Alatae: acrid in the mouth, hardship, cold in nature, tepor; GUIXIN, spleen channel.Parasite killing, antipruritic.Cure mainly neurodermatitis, psoriasis, eczema, skin pruritus, furuncle pus infections." choosing of Simao, Yunnan Chinese herbal medicine " carries: " parasite killing, antipruritic, control neurodermatitis, psoriasis, eczema, skin pruritus, furuncle swells rash.”
Cortex cocois radicis: sweet in the mouth, property are flat; Enter stomach, spleen, large intestine channel.Xu-tonic, QI invigorating is dispeled the wind, the infantile malnutrition that disappears parasite killing, and nourishing, clearing away summer-heat quenches one's thirst.Cure mainly children's and wash worm, fasciolopsiasis buski, summer-heat class is thirsty, deficiency of body fluid thirsty.Modern medicine study confirms, edible when the suitable heating of Cortex cocois radicis or hot weather, xerostomia are thirsty, and Cortex cocois radicis is suitable for congestive heart failure person and eats simultaneously.
Bulbus Allii Macrostemonis: acrid in the mouth, hardship, warm in nature; Return lung, the heart, stomach, large intestine channel.Activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.Cure mainly the thorough back of the body of obstruction of qi in the chest and cardialgia, breast gastral cavity painful abdominal mass is vexed, cough with asthma abundant expectoration, epigastric pain, heavy after letting out dysentery, leucorrhea, furuncle carbuncle." detailed outline " carries: " control SHAO YIN syndrome to faint and inverse let out dysentery, and thoracic obstruction twinge, the therapeutic method to keep the adverse QI flowing downwards is fallen apart blood, antiabortive.Temperature compensation is supporing yang road.”
The present invention compared with prior art, has following beneficial effect:
The Chinese crude drug that choice of drug compatibility of the present invention is suitable, has effect of heart tonifying hepatoprotective, warming and invigorating the spleen and stomach, can improve body's immunity, adjusting blood lipid metabolism, promotes that cardiac function recovers, evident in efficacy, safe without toxic side effect, can be widely used in anginal clinical treatment.
Detailed description of the invention
The present invention is done supplementary further below in conjunction with specific embodiment, but do not limit the present invention in any way.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
The preparation method of medicine of the present invention, is characterized in that: comprise following processing step:
(1) by adding the water of 8 times amount after Bulbus Lilii, Caulis Clematidis Armandii, Cortex Ailanthi, Rhizoma Paridis, Radix Clerodenri Cyrtophylli and Cortex cocois radicis mixing, extracting 2 ~ 3 hours, filtering, taking liquid; In remaining residue, add the water of 6 times amount again, extract 1 ~ 2 hour, filter, taking liquid; Merge twice medicinal liquid, be condensed into the thick paste of relative density 1.10 ~ 1.15 under 60 DEG C of environment, for subsequent use;
(2) get Rhizoma Chuanxiong to clean, section is dried, and sprays evenly with yellow wine, and putting stir-fry in pot is degree to micro-Jiao, and taking-up cools, and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) get Radix Aconiti Kusnezoffii to clean, dry, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Caulis et Radix Tetrastigmatis Planicaulis, Radix Cudraniae and Cortex Moutan are ground into powder, cross 200 order fine powders, for subsequent use.
(5) get Radix Cirsii Japonici, Herba Violae, Folium Cassiae Alatae and Bulbus Allii Macrostemonis to clean, strand juice, filters, obtains juice for subsequent use;
(6) Radix Saposhnikoviae is cleaned decontamination, section is dried, and be placed in slow fire in pot and be fried to surface in black, taking-up is dried in the air cool, is placed in mortar and grinds into powder, crosses 240 order fine powders, for subsequent use.
(7) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (6), make capsule, be the anginal medicine for the treatment of of the present invention.
Usage and dosage: oral, every day 3 times, each 2, warm water delivery service after meal; Within 12 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can cure, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the anginal medicine for the treatment of, select the routine clinical observation of patient with angina pectoris 152 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 78 example, wherein male 40 example, women 38 example, 40 ~ 71 years old age, 55.3 years old mean age, the shortest person of the course of disease 3 months, most elder 5 years, average 2 years.Matched group 74 example, wherein male 38 example, women 36 example, 41 ~ 70 years old age, 53.3 years old mean age, the shortest person of the course of disease 4 months, most elder 6 years, average 3 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 3 times, each 2, warm water delivery service after meal; Within 12 days, be 1 course for the treatment of, take 2 ~ 3 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes SUXIAO JIUXIN WAN, and by specification or doctor's advice are taken, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: the transference cures such as chest pain, internal metabolism recovers normal, and patient's body's immunity strengthens.
(2) take a turn for the better: the symptoms such as chest pain are alleviated to some extent, and immunologic function is recovered to some extent.
(3) invalid: clinical symptoms is unchanged.
4, result:
Select in the treatment group of medicine of the present invention, cure 48 examples, take a turn for the better 26 examples, invalid 4 examples, cure rate 61.5%, total effective rate 94.9%.
Cure 21 examples in matched group, take a turn for the better 21 examples, invalid 32 examples, cure rate 28.4%, total effective rate 56.8%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Dong, female, 43 years old, Shanxi people from Lvliang City.Patient is because of overworked processus aboralis sense ambition severe pain, and if thorn is as strand, and with sensation of oppression over the chest with shortness of breath, nervous, activity then more very.To our hospital, be angina pectoris outbreak through Electrocardioscopy, take medicine of the present invention, after taking 1 course for the treatment of, symptom disappears substantially, and after taking 2 courses for the treatment of, symptom disappears completely, normal ECG, follows up a case by regular visits to and does not recur for 1 year.
2, Xue, man, 56 years old, Zhejiang Huzhou people.Prominent sense pareordia twinge during patient's morning exercises, pain are drawn shoulder and are carried on the back and be ictal, and certainly take SUXIAO JIUXIN WAN remission after about ten minutes, rear recurrent number increases gradually.To our hospital, finding that there is property of Electrocardioscopy myocardial ischemia phenomenon, recommends through doctor, takes medicine of the present invention, after taking 1 course for the treatment of, symptom is obviously improved, after taking the 2nd course for the treatment of, and recovery from illness, general malaise transference cure, Electrocardioscopy is normal, follows up a case by regular visits to and does not recur for 1 year.
3, Cao, man, 70 years old, From Shandong Rizhao people.Patient is feeling of oppression and pain in the chest always, nervous cardiopalmus, and with symptoms such as serious limbs fatigues.After send into hospital admission by children, through Electrocardioscopy be angina pectoris outbreak.Take multi-medicament all without positive effect, recommend to take medicine of the present invention by doctor, after taking 2 courses for the treatment of, symptom disappears substantially, fully recovers, follow up a case by regular visits to, do not recur so far after taking 4 courses for the treatment of.

Claims (5)

1. treat an anginal medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Bulbus Lilii 38 ~ 68 portions of Caulis Clematidis Armandiis 33 ~ 63 parts of Rhizoma Chuanxiongs 33 ~ 58 parts of Radix Aconiti Kusnezoffiis 28 ~ 58 parts
Caulis et Radix Tetrastigmatis Planicaulis 28 ~ 58 portions of Radix Cirsii Japonicis 28 ~ 53 parts of Radix Cudraniaes 23 ~ 53 parts of Cortex Moutans 23 ~ 53 parts
Cortex Ailanthi 23 ~ 48 portions of Herba Violaes 18 ~ 48 parts of Rhizoma Paridis 18 ~ 43 parts of Radix Clerodenri Cyrtophyllis 18 ~ 43 parts
Radix Saposhnikoviae 18 ~ 48 parts of Folium Cassiae Alataes 13 ~ 43 portions of Cortex cocois radiciss 13 ~ 38 parts of Bulbus Allii Macrostemonis 8 ~ 33 parts.
2. one according to claim 1 treats anginal medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Bulbus Lilii 43 ~ 63 portions of Caulis Clematidis Armandiis 38 ~ 58 parts of Rhizoma Chuanxiongs 37 ~ 54 parts of Radix Aconiti Kusnezoffiis 33 ~ 53 parts
Caulis et Radix Tetrastigmatis Planicaulis 33 ~ 53 portions of Radix Cirsii Japonicis 32 ~ 49 parts of Radix Cudraniaes 28 ~ 48 parts of Cortex Moutans 28 ~ 48 parts
Cortex Ailanthi 27 ~ 44 portions of Herba Violaes 23 ~ 43 parts of Rhizoma Paridis 22 ~ 39 parts of Radix Clerodenri Cyrtophyllis 22 ~ 39 parts
Radix Saposhnikoviae 23 ~ 43 parts of Folium Cassiae Alataes 18 ~ 38 portions of Cortex cocois radiciss 17 ~ 34 parts of Bulbus Allii Macrostemonis 12 ~ 29 parts.
3. one according to claim 1 treats anginal medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Bulbus Lilii 48 ~ 58 portions of Caulis Clematidis Armandiis 43 ~ 53 parts of Rhizoma Chuanxiongs 41 ~ 50 parts of Radix Aconiti Kusnezoffiis 38 ~ 48 parts
Caulis et Radix Tetrastigmatis Planicaulis 38 ~ 48 portions of Radix Cirsii Japonicis 36 ~ 45 parts of Radix Cudraniaes 33 ~ 43 parts of Cortex Moutans 33 ~ 43 parts
Cortex Ailanthi 31 ~ 40 portions of Herba Violaes 28 ~ 38 parts of Rhizoma Paridis 26 ~ 35 parts of Radix Clerodenri Cyrtophyllis 26 ~ 35 parts
Radix Saposhnikoviae 28 ~ 38 parts of Folium Cassiae Alataes 23 ~ 33 portions of Cortex cocois radiciss 21 ~ 30 parts of Bulbus Allii Macrostemonis 16 ~ 26 parts.
4. one according to claim 1 treats anginal medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Bulbus Lilii 53 portions of Caulis Clematidis Armandiis 48 parts of Rhizoma Chuanxiongs 45 parts of Radix Aconiti Kusnezoffiis 43 parts
Caulis et Radix Tetrastigmatis Planicaulis 43 portions of Radix Cirsii Japonicis 40 parts of Radix Cudraniaes 38 parts of Cortex Moutans 38 parts
Cortex Ailanthi 36 portions of Herba Violaes 33 parts of Rhizoma Paridis 30 parts of Radix Clerodenri Cyrtophyllis 30 parts
Radix Saposhnikoviae 33 parts of Folium Cassiae Alataes 28 portions of Cortex cocois radiciss 26 parts of Bulbus Allii Macrostemonis 20 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for anginal medicine, it is characterized in that: comprise following processing step:
(1) by adding the water of 8 times amount after Bulbus Lilii, Caulis Clematidis Armandii, Cortex Ailanthi, Rhizoma Paridis, Radix Clerodenri Cyrtophylli and Cortex cocois radicis mixing, extracting 2 ~ 3 hours, filtering, taking liquid; In remaining residue, add the water of 6 times amount again, extract 1 ~ 2 hour, filter, taking liquid; Merge twice medicinal liquid, be condensed into the thick paste of relative density 1.10 ~ 1.15 under 60 DEG C of environment, for subsequent use;
(2) get Rhizoma Chuanxiong to clean, section is dried, and sprays evenly with yellow wine, and putting stir-fry in pot is degree to micro-Jiao, and taking-up cools, and grinds into powder, crosses 160 order fine powders, for subsequent use;
(3) get Radix Aconiti Kusnezoffii to clean, dry, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Caulis et Radix Tetrastigmatis Planicaulis, Radix Cudraniae and Cortex Moutan are ground into powder, cross 200 order fine powders, for subsequent use;
(5) get Radix Cirsii Japonici, Herba Violae, Folium Cassiae Alatae and Bulbus Allii Macrostemonis to clean, strand juice, filters, obtains juice for subsequent use;
(6) Radix Saposhnikoviae is cleaned decontamination, section is dried, and be placed in slow fire in pot and be fried to surface in black, taking-up is dried in the air cool, is placed in mortar and grinds into powder, crosses 240 order fine powders, for subsequent use;
(7) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (6), make capsule, be the anginal medicine of described treatment.
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