CN103977182A - Traditional Chinese medicinal plaster for treating knee osteoarthritis and preparation method thereof - Google Patents

Traditional Chinese medicinal plaster for treating knee osteoarthritis and preparation method thereof Download PDF

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CN103977182A
CN103977182A CN201410243526.2A CN201410243526A CN103977182A CN 103977182 A CN103977182 A CN 103977182A CN 201410243526 A CN201410243526 A CN 201410243526A CN 103977182 A CN103977182 A CN 103977182A
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chinese medicinal
medicinal plaster
radix
rhizoma
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杨家顺
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杨家顺
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Abstract

The invention discloses a traditional Chinese medicinal plaster for treating knee osteoarthritis and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The effective components for preparing the traditional Chinese medicinal plaster are prepared from the following raw materials: hedyotis auricularia, mustard seed, fevervine, edgeworthia chrysantha, sambucus chinensis, serrate chloranthus root, lygodium japonicum, polygonum cuspidatum, roughhaired holly root, cassia sophera, bigleaf fig bark, dentiferous dendropanax root and stem, alocasia rhizome, clematis filamentosa dunn, nidus vespae and Japanese balanophora. The traditional Chinese medicinal plaster is compatible in medicinal materials, accords with traditional Chinese medicine and modern medical theory, has the effects of diminishing inflammation and edema, activating blood circulation to remove stasis, relaxing tendon and activating collaterals, and strengthening tendons and bones, has a remarkable curative effect when being used for treating knee osteoarthritis, is convenient to use, safe and reliable, does not have toxic or side effect, prevents relapse after the knee osteoarthritis is healed, helps a patient get rid of pains, has remarkable and practical effects, and is worthy of wide popularization and application in clinical therapy.

Description

A kind of Chinese medicinal plaster and preparation method for the treatment of knee osteoarthritis
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicinal plaster and preparation method for the treatment of knee osteoarthritis.
Background technology
Osteoarthritis is a kind of chronic joint disease, and its main change is degeneration and the insecondary hyperosteogeny of articular cartilage face.Main manifestations is arthralgia and movable dumb, and x-ray performance joint space narrows down, and subchondral bone matter is fine and close, and bone trabecula fracture, has sclerosis and cystis degeneration, later stage epiphysis distortion, and articular surface is uneven.Intraarticular cartilage peels off, and the cracked joint that enters of sclerotin forms articular mobile corpus.Osteoarthritis is named again degenerative osteoarthritis, and actual not inflammation, is mainly degeneration, belongs to the aging of joint premature aging, particularly articular cartilage; Osteoarthritis is representing the aging in joint, therefore be referred to as senile arthritis.
Gonarthritis is kneed common disease, is the far sick and wounded of knee position.Due to far sick and wounded, be not familiar with, do not understood sick and wounded feature far away, according to patient, the impression of kneed symptom is described, be commonly considered as osteoarthritis, thought that the cause of disease is mainly degeneration and the insecondary hyperosteogeny of articular cartilage change and surface of bone.Arthritis general reference occurs in the inflammatory diseases of human synovial and surrounding tissue thereof, can be divided into tens of kinds.The arthritic of China has more than 100,000,000, and number is in continuous increase.Clinical manifestation be joint red, swollen, hot, bitterly, dysfunction and joint deformity, severe patient cause joint disabled, affect patients ' life quality.
The clinical curative effect of medication being used for the treatment of is slow at present, there is no specific medicament, can only take the Therapeutic Method of having an operation, such as Minimally Invasive Surgerys such as arthroscopes, in treatment clinical course, if operating process is improper, may cause the inner infection of articular cavity, patient process is more painful; And endo-medicine toxic and side effects is larger for patients, spy develops a kind of knee osteoarthritis external Chinese medicinal plaster for the treatment of for this reason, is the Patients with Knee Osteoarthritis misery that throws off one's illness.
Summary of the invention
The invention provides a kind of Chinese medicinal plaster and preparation method for the treatment of knee osteoarthritis; The selected medical material compatibility of Chinese medicinal plaster of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is the effect of anti-inflammation detumescence, blood circulation promoting and blood stasis dispelling, channels sootheing and network vessel quickening, strong muscles and bones, and for the treatment of knee osteoarthritis, there is significant curative effect, easy to use, safe and reliable, without any side effects, non-relapse after healing, makes patient break away from misery, special effect is practical, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicinal plaster for knee osteoarthritis, raw material composition and the parts by weight of making described Chinese medicinal plaster effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicinal plaster effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicinal plaster effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicinal plaster effective ingredient are:
Treat a preparation method for the Chinese medicinal plaster of knee osteoarthritis, comprise following processing step:
(1) Auricled Hedyotis Herb, Spora Lygodii grass, Radix Ilicis Asprellae, Semen Cassiae Sopherae, Cortex fici lacoris, Rhizoma alcasiae odorae, Clematis filamentosa Dunn and Herba balanophorae japonicae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) by Semen Sinapis decontamination, be placed in and in frying pan, be fried to buff and have pungent abnormal smells from the patient to overflow, take out and dry in the air coolly, be placed in mortar and grind into powder, cross 200 order fine powders, standby;
(3) fevervine, Edgeworthia chrysantha Lindl., Radix Chloranthi Serrati, Rhizoma Polygoni Cuspidati and Nidus Vespae decontamination, after oven dry, carry out pulverization process, grinds into powder, crosses 180 order fine powders, standby;
(4) Rhizoma seu Herba Elatostematis stewardii and Radix Dendropanacis are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, standby;
(5) by the prepared thick paste of above-mentioned steps (1), step (2) and (3) prepared fine powder mixing and step (1) and (4) prepared thick paste mixing, be modulated to ointment, be labelled on sterilization nonwoven gauze, make plaster, obtain the Chinese medicinal plaster for the treatment of knee osteoarthritis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Auricled Hedyotis Herb: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, removing heat from blood detumescence.For cold, fever, cough due to lung-heat, laryngalgia, acute conjunctivitis, enteritis, dysentery; Venom is controlled in external, traumatic injury, carbuncle pyogenic infections from tumour or sore, mastitis, eczema.
Semen Sinapis: acrid in the mouth, warm in nature; Return lung meridian.Warming spleen and stomach for dispelling cold, promoting the circulation of QI eliminating phlegm, the meridian dredging, detumescence poison.Control cold syndrome of the stomach and tell food, trusted subordinate's pain, lung cold cough, arthralgia aggravated by cold, sore throat, carbuncle of yin nature, the tuberculosis of bone and joint, traumatic injury.< < detailed outline > > carries: " warming spleen and stomach for dispelling cold, eliminating phlegm profit key.Control cold syndrome of the stomach and tell food, lung cold cough, air-cooled pain due to disorder of QI, locked mouth lockjaw.Dissipation carbuncle, blood stasis.”
Fevervine: sweet in the mouth, micro-hardship, property is flat.Expelling wind and removing dampness, promoting digestion and removing stagnation, cough-relieving pain relieving.For bones and muscles pain due to rheumatism, traumatic injury, traumatic pain, liver and gall, gastrointestinal angor, icterohepatitis, enteritis, dysentery, dyspepsia, infantile malnutrition, hemoptysis of pulmonary tuberculosis, bronchitis, the leukopenia that radiation reaction causes, pesticide intoxication; Dermatitis is controlled in external, eczema, sore swollen toxin.
Edgeworthia chrysantha Lindl.: sweet in the mouth, warm in nature.Relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain, dispelling pathogenic wind for improving eyesight.For rheumatic arthralgia, lumbago, conjunctival congestion and pain of eye, nyctalopia; Traumatic injury is controlled in external, fracture.
Rhizoma seu Herba Elatostematis stewardii: bitter in the mouth, property is flat.Promoting tissue regeneration by removing blood stasis, relaxing muscles and tendons and activating QI and blood in the collateral, strong muscles and bones.Dispelling the wind and dampness pathogens osteodynia, traumatic injury, synthetism.According to < < the southern regions of the Yunnan Province book on Chinese herbal medicine > >, carry: " row twelve channels and collaterals is controlled muscles and bones phlegm-fire, pain, numb hand and foot meciless.Loose scrofula brothers sucutaneous nodule, controls traumatic injury, synthetism." modern medicine study confirms, the contained Quercetin of Rhizoma seu Herba Elatostematis stewardii, quercitrin, Isoquercitrin etc. have stronger inhibitory action to Staphylococcus aureus bacillus, Bacillus typhi, the contained obvious antiinflammatory action of hyperin tool.
Radix Chloranthi Serrati: acrid in the mouth, warm in nature is poisonous; Return Liver Channel.Relaxing muscles and tendons and activating QI and blood in the collateral, wind-expelling pain-stopping, subduing swelling and detoxicating.For traumatic injury, lumbago, skelalgia of rheumatism, furuncle swelling toxin, venom.< < Zhejiang conventional medical herbs > > among the people carries: " removing blood stasis and activating blood flow, anti-inflammation.Control and get injured by a fall, sprain, fracture, furuncle and phyma, amenorrhea.”
Spora Lygodii grass: sweet in the mouth, micro-hardship, cold in nature.Clearing away heat-damp and promoting diuresis, relaxing muscles and tendons and activating QI and blood in the collateral, hemostasis.Cure mainly urinary tract infection, lithangiuria, oedema due to nephritis, hepatitis, dysentery, conjunctival congestion and swelling pain, rheumatic arthralgia, muscles and bones is numb, injury and bone fracture, traumatic hemorrhage.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature; Return liver, gallbladder, lung meridian.Heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, postnatal blood stasis is not Xiaed , WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, traumatic injury, carbuncle sore tumefacting virus.Modern medicine study confirmation, Huzhang has obvious anastalsis to traumatic hemorrhage, and for oral administration also have anastalsis to upper gastrointestinal hemorrhage, and Rhizoma Polygoni Cuspidati extract has antipyretic effect, and scald wound is had convergence, protected from infection and antiinflammation.
Radix Ilicis Asprellae: bitter in the mouth, sweet, cold in nature; Return lung, liver, large intestine channel.Clearing away heat and promoting production of body fluid, dissipating blood stasis removing toxic substances.Main flu, headache, dizzy, calentura excessive thirst, eruptive disease, diarrhea of heat type, lung abscess, pertussis, laryngopharynx swelling and pain, hemorrhoidal bleeding, gonorrhea, furuncle swelling toxin, traumatic injury.The medicine will > > of < < Nanning City carries: " heat-clearing and toxic substances removing, lung moistening is quenched the thirst.Soothe sore throat thirsty, hemoptysis, eruptive disease.”
Semen Cassiae Sopherae: sweet in the mouth, hardship, property is flat, nontoxic; Return lung, stomach, large intestine channel.Liver heat removing and eyesight improving, during stomach invigorating is adjusted, intestine moistening removing toxic substances.Main conjunctival congestion and swelling pain, dizzy feeling of fullness in the head, oral erosion, habitual constipation, infantile malnutrition, dysentery, malaria.< < Bencao Shiyi > > carries: " fire is processed and drunk extremely perfume, and expectorant is quenched the thirst, and makes us sitting up, in tune.”
Cortex fici lacoris: bitter in the mouth, acid, warm in nature.Dispelling wind and removing obstruction in the collateral, killing parasites for relieving itching.Main air wet numbness, numb limbs and tense tendons, hemiplegia, tinea skin ulcer.< < vegetation just square > > is carried: " dispel the wind, dehumidifying, detumescence is full.Control extremity insensitive impediment, apathy, hemiplegia.”
Radix Dendropanacis: sweet in the mouth, warm in nature.Expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.For migraine, brachial plexus neuritis, rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lambago and skelalgia, hemiplegia, traumatic injury, bruise; External is controlled on cutter hemorrhage.< < Zhejiang conventional medical herbs > > among the people carries: " expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, pain relieving.”
Rhizoma alcasiae odorae: taste is micro-pungent, puckery, cold in nature, poisonous; GUIXIN, liver, gallbladder, large intestine channel.Heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, mass dissipating and swelling eliminating.Cure mainly influenza, flu, stomachache, pulmonary tuberculosis, rheumatic ostalgia, furuncle, swollen ulcer drug, scrofula, attached bone carbuncle, class is bald, scabies, worm venom.
Clematis filamentosa Dunn: bitter in the mouth, slightly cool in nature; GUIXIN, Liver Channel.Sedation and analgesia, clearing away liver-fire, mind calming god, blood pressure lowering, removing obstruction in the collateral to relieve pain.Main hypertension, insomnia, headache, numb limbs and tense tendons, wind-heat of liver channel, conjunctival congestion and swelling pain, acute toothache, rheumatic arthralgia.Modern medicine study confirms, Clematis filamentosa Dunn is to improving the caused symptom of hypertension, as headache, giddy, feeling of fullness in the head, numb limbs and tense tendons, insomnia etc. have good curative effect, simultaneously preliminary observation all has therapeutical effect to the hemiplegic patient that patients with coronary heart disease and cerebrovascular accident are caused.
Nidus Vespae: sweet in the mouth, property is flat; Return stomach warp.The counteracting toxic substances that dispels the wind, parasite killing pain relieving, antiallergic.< < Simao, Yunnan Chinese herbal medicine selects > > to carry: " relaxing muscles and tendons and activating QI and blood in the collateral, method rheumatism, diuresis.Cure mainly rheumatic arthritis, waist knee joint arthralgia chiefly caused by damp pathogen, oedema due to nephritis." modern medicine study confirmation, Nidus Vespae preparation has the effect that promotes Immune Function.
Herba balanophorae japonicae: bitter in the mouth, puckery, cold in nature; Return lung, large intestine channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing.Main cough spitting of blood, metrorrhagia, discharging fresh blood stool, swelling and pain of hemorrhoid, syphilis, treats skin ulcer, and child penis is swollen.< < detailed outline > > carries: " relieving alcoholic intoxication is controlled wine long-pending.”
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of Chinese medicinal plaster of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is the effect of anti-inflammation detumescence, blood circulation promoting and blood stasis dispelling, channels sootheing and network vessel quickening, strong muscles and bones, and for the treatment of knee osteoarthritis, there is significant curative effect, easy to use, safe and reliable, without any side effects, non-relapse after healing, makes patient break away from misery, special effect is practical, wide popularization and application on clinic.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicinal plaster effective ingredient of the present invention forms and weight is:
The preparation method of Chinese medicinal plaster of the present invention, comprises following processing step:
(1) Auricled Hedyotis Herb, Spora Lygodii grass, Radix Ilicis Asprellae, Semen Cassiae Sopherae, Cortex fici lacoris, Rhizoma alcasiae odorae, Clematis filamentosa Dunn and Herba balanophorae japonicae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) by Semen Sinapis decontamination, be placed in and in frying pan, be fried to buff and have pungent abnormal smells from the patient to overflow, take out and dry in the air coolly, be placed in mortar and grind into powder, cross 200 order fine powders, standby;
(3) fevervine, Edgeworthia chrysantha Lindl., Radix Chloranthi Serrati, Rhizoma Polygoni Cuspidati and Nidus Vespae decontamination, after oven dry, carry out pulverization process, grinds into powder, crosses 180 order fine powders, standby;
(4) Rhizoma seu Herba Elatostematis stewardii and Radix Dendropanacis are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, standby;
(5) by the prepared thick paste of above-mentioned steps (1), step (2) and (3) prepared fine powder mixing and step (1) and (4) prepared thick paste mixing, be modulated to ointment, be labelled on sterilization nonwoven gauze, make plaster, obtain the Chinese medicinal plaster for the treatment of knee osteoarthritis of the present invention.
Usage and dosage: external, every day twice, each 1 time sooner or later, each 1 pastes, and cleans behind affected part, pastes affected part, within 6 days, is 1 course for the treatment of, and can fully recover 3~4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
The raw material of Chinese medicinal plaster effective ingredient of the present invention forms and weight is:
Chinese medicinal plaster preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of Chinese medicinal plaster effective ingredient of the present invention forms and weight is:
Chinese medicinal plaster preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of Chinese medicinal plaster effective ingredient of the present invention forms and weight is:
Chinese medicinal plaster preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.Embodiment 5
The raw material of Chinese medicinal plaster effective ingredient of the present invention forms and weight is:
Chinese medicinal plaster preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicinal plaster for the treatment of knee osteoarthritis, select the routine clinical observation of Patients with Knee Osteoarthritis 384 make a definite diagnosis, patient to be divided at random two groups for the treatment of group and matched groups, treatment group 192 examples, male's 96 examples wherein, women's 96 examples, 50~79 years old age, 64.5 years old mean age, average course of disease 8 years; Matched group 192 examples, male's 96 examples wherein, women's 96 examples, 51~78 years old age, 64.5 years old mean age, average course of disease 8 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is used Chinese medicinal plaster of the present invention, external, and every day twice, each 1 time sooner or later, each 1 pastes, and cleans behind affected part, pastes affected part, within 6 days, is 1 course for the treatment of, and can fully recover 3~4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken diclofenac sodium extended release capsule, and this product must be swallowed by granulate, do not chew, and a 50mg (1), 2 times on the one, the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: knee joint swelling, pain disappear, bend and stretch range of activity and recover normal, freely, physical recovery is as usual in walking.
(2) effective: knee joint swelling and pain all have and alleviates in various degree and alleviate, bend and stretch range of activity and also obviously improve, health recovers to some extent.
(3) effective: knee joint swelling and pain all have and alleviates in various degree and alleviate, and bend and stretch range of activity and also make moderate progress, and health obviously recovers.
(4) invalid: by treating patella swelling and pain all without alleviating.
4, result:
Select in the treatment group of Chinese medicinal plaster of the present invention, cure 99 examples, effective 50 examples, effective 40 examples, invalid 3 examples, cure rate 51.6%, total effective rate 98.4%.
In matched group, cure 43 examples, effective 35 examples, effective 20 examples, invalid 94 examples, cure rate 22.4%, total effective rate 51%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, river, female, 51 years old, people from Hedong District, Tianjin.Existing 3 years of patient's two knee joint sorenesses, have Knee Trauma history and the history of catching cold.Though through treatments such as Chinese medicine and western medicine pain relievings, stop when two knee joint sorenesses are done still time, rear knee joint soreness increases the weight of, stair activity all needs handrail, and seat erects difficulty.X takes the photograph sheet prompting: it is loose that knee joint is bone, and joint space narrows down.Check and find, two knee joints are tenderness around, mild swelling and limping, two knee joint mobilities are limited to 45 °, have interlocking to levy, McMurray's test (+), lateroflexion (±), floating kneecap (±), is diagnosed as knee osteoarthritis, give Chinese medicinal plaster treatment of the present invention, use after 1 course for the treatment of, two knee joints are ached and are alleviated, swelling disappears, and all the other symptoms alleviate, and continues to use after 2 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
2, history, man, 55 years old, people from Shanghai Pudong New Area.Nearly 1 year of patient's two gonalgia, over latter 3 months, right swelling and pain in knee obviously increases the weight of, and upper all needs staircase downstairs, and seat dysstasia is met overcast and rainy symptom obvious.Check and find, inner side tenderness under kneecap, right knee joint is micro-swollen, is diagnosed as knee osteoarthritis.Use Chinese medicinal plaster treatment of the present invention, use after 2 courses for the treatment of, above symptom is clearly better, and continues to use after 2 courses for the treatment of, and recovery from illness, follows up a case by regular visits to after 2 years without recurrence.
3, turn round and look at certain, female, 59 years old, people from Mudanjiang, Heilungkiang.Existing 5 years of patient's two knee joint sorenesses, have Knee Trauma history.Knee joint soreness increases the weight of gradually, and stair activity all needs handrail, and seat erects difficulty.X takes the photograph sheet prompting: it is loose that knee joint is bone, and joint space narrows down.Check: tenderness (+), mild swelling and the limping around of two knee joints.Be diagnosed as knee osteoarthritis.Chinese medicine and western medicine has taken many, and curative effect is not fine, changes and uses Chinese medicinal plaster treatment of the present invention, uses after 1 course for the treatment of, and two knee joints are ached and alleviated, and swelling disappears, and all the other symptoms obviously alleviate, continue to use after 2 courses for the treatment of, and transference cure, recovery from illness, follows up a case by regular visits to so far not recurrence.
4, marquis, man, 62 years old, Tongling, Anhui Province people.Nearly 1 year of patient's two gonalgia, right swelling and pain in knee obviously increases the weight of, and upper all needs staircase downstairs, and seat dysstasia is met overcast and rainy symptom obvious, and morning is stiff, and idol has interlocking phenomenon.Check: inner side tenderness under kneecap: left knee joint (+), right knee joint (++); Right knee joint is micro-swollen, right Range of motion of knee joint: 45 °, be diagnosed as knee osteoarthritis.Use Chinese medicinal plaster treatment of the present invention, use after 1 course for the treatment of, symptom is alleviated to some extent, continues to use after 1 course for the treatment of, and transference cure, follows up a case by regular visits to after 2 years without recurrence.
5, Shao, female, 67 years old, people from Baicheng, Jilin.Existing 4 years of patient's two knee joint sorenesses, have Knee Trauma history and the history of catching cold.Though through treatments such as Chinese medicine and western medicine pain relievings, stop when two knee joint sorenesses are done still time, recently, knee joint soreness increases the weight of, stair activity all needs handrail, and seat erects difficulty.Adopt Chinese medicinal plaster treatment of the present invention, use after 1 course for the treatment of, symptom obviously alleviates, and uses after 2 courses for the treatment of, and the disappearance of all diseases is fully recovered, and follows up a case by regular visits to without recurrence after half a year.
6, the Meng, man, 70 years old, people from Shijiazhuang, Hebei.Nearly 2 years of the right gonalgia of patient, right swelling and pain in knee obviously increased the weight of afterwards, upper all needed staircase downstairs, and seat dysstasia is met overcast and rainy symptom obvious.Check: inner side tenderness under kneecap, right knee joint is micro-swollen, and 45 ° of right Range of motion of knee joints, are diagnosed as knee osteoarthritis.Use Chinese medicinal plaster treatment of the present invention, use after 2 courses for the treatment of, right swelling and pain in knee obviously alleviates, and continues to use after 2 courses for the treatment of, and transference cure, follows up a case by regular visits to so far not recurrence.

Claims (5)

1. a Chinese medicinal plaster for the treatment of knee osteoarthritis, is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal plaster effective ingredient are:
42~66 parts of 42~66 parts of Edgeworthia chrysantha Lindl. of 43~67 parts of fevervines of 45~69 parts of Semen Sinapiss of Auricled Hedyotis Herb
39~63 parts of 40~64 parts of Rhizoma Polygoni Cuspidati of 40~64 parts of Spora Lygodii grass of 41~65 parts of Radix Chloranthi Serrati of Rhizoma seu Herba Elatostematis stewardii
36~60 parts of 36~60 parts of Radix Dendropanacis of 37~61 parts of Cortex fici lacoriss of 39~63 parts of Semen Cassiae Sopherae of Radix Ilicis Asprellae
25~49 parts of 30~54 parts of Herba balanophorae japonicae of 33~57 parts of Nidus Vespae of 34~58 parts of Clematis filamentosa Dunn of Rhizoma alcasiae odorae.
2. a kind of Chinese medicinal plaster for the treatment of knee osteoarthritis according to claim 1, is characterized in that: the raw material of making described Chinese medicinal plaster effective ingredient forms and parts by weight are:
46~62 parts of 46~62 parts of Edgeworthia chrysantha Lindl. of 47~63 parts of fevervines of 49~65 parts of Semen Sinapiss of Auricled Hedyotis Herb
43~59 parts of 44~60 parts of Rhizoma Polygoni Cuspidati of 44~60 parts of Spora Lygodii grass of 45~61 parts of Radix Chloranthi Serrati of Rhizoma seu Herba Elatostematis stewardii
40~56 parts of 40~56 parts of Radix Dendropanacis of 41~57 parts of Cortex fici lacoriss of 43~59 parts of Semen Cassiae Sopherae of Radix Ilicis Asprellae
29~45 parts of 34~50 parts of Herba balanophorae japonicae of 37~53 parts of Nidus Vespae of 38~54 parts of Clematis filamentosa Dunn of Rhizoma alcasiae odorae.
3. a kind of Chinese medicinal plaster for the treatment of knee osteoarthritis according to claim 1, is characterized in that: the raw material of making described Chinese medicinal plaster effective ingredient forms and parts by weight are:
50~58 parts of 50~58 parts of Edgeworthia chrysantha Lindl. of 51~59 parts of fevervines of 53~61 parts of Semen Sinapiss of Auricled Hedyotis Herb
47~55 parts of 48~56 parts of Rhizoma Polygoni Cuspidati of 48~56 parts of Spora Lygodii grass of 49~57 parts of Radix Chloranthi Serrati of Rhizoma seu Herba Elatostematis stewardii
44~52 parts of 44~52 parts of Radix Dendropanacis of 45~53 parts of Cortex fici lacoriss of 47~55 parts of Semen Cassiae Sopherae of Radix Ilicis Asprellae
33~41 parts of 38~46 parts of Herba balanophorae japonicae of 41~49 parts of Nidus Vespae of 42~50 parts of Clematis filamentosa Dunn of Rhizoma alcasiae odorae.
4. a kind of Chinese medicinal plaster for the treatment of knee osteoarthritis according to claim 1, is characterized in that: the raw material of making described Chinese medicinal plaster effective ingredient forms and parts by weight are:
54 parts of 54 parts of Edgeworthia chrysantha Lindl. of 55 parts of fevervines of 57 parts of Semen Sinapiss of Auricled Hedyotis Herb
51 parts of 52 parts of Rhizoma Polygoni Cuspidati of 52 parts of Spora Lygodii grass of 53 parts of Radix Chloranthi Serrati of Rhizoma seu Herba Elatostematis stewardii
48 parts of 48 parts of Radix Dendropanacis of 49 parts of Cortex fici lacoriss of 51 parts of Semen Cassiae Sopherae of Radix Ilicis Asprellae
37 parts of 42 parts of Herba balanophorae japonicae of 45 parts of Nidus Vespae of 46 parts of Clematis filamentosa Dunn of Rhizoma alcasiae odorae.
5. as described in claim 1~4 any one, treat a preparation method for the Chinese medicinal plaster of knee osteoarthritis, it is characterized in that: comprise following processing step:
(1) Auricled Hedyotis Herb, Spora Lygodii grass, Radix Ilicis Asprellae, Semen Cassiae Sopherae, Cortex fici lacoris, Rhizoma alcasiae odorae, Clematis filamentosa Dunn and Herba balanophorae japonicae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) by Semen Sinapis decontamination, be placed in and in frying pan, be fried to buff and have pungent abnormal smells from the patient to overflow, take out and dry in the air coolly, be placed in mortar and grind into powder, cross 200 order fine powders, standby;
(3) fevervine, Edgeworthia chrysantha Lindl., Radix Chloranthi Serrati, Rhizoma Polygoni Cuspidati and Nidus Vespae decontamination, after oven dry, carry out pulverization process, grinds into powder, crosses 180 order fine powders, standby;
(4) Rhizoma seu Herba Elatostematis stewardii and Radix Dendropanacis are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, standby;
(5) by the prepared thick paste of above-mentioned steps (1), step (2) and (3) prepared fine powder mixing and step (1) and (4) prepared thick paste mixing, be modulated to ointment, be labelled on sterilization nonwoven gauze, make plaster, obtain the Chinese medicinal plaster for the treatment of knee osteoarthritis of the present invention.
CN201410243526.2A 2014-06-02 2014-06-02 Traditional Chinese medicinal plaster for treating knee osteoarthritis and preparation method thereof Pending CN103977182A (en)

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KR101914202B1 (en) * 2017-06-26 2018-11-01 재단법인 경기도경제과학진흥원 Composition for treating, preventing or alleviating bone diseases comprising extract of edgeworthia papyrifera

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CN103463381A (en) * 2013-09-25 2013-12-25 张国辉 Traditional Chinese medicine preparation for treating rheumatism bone pain and preparation method thereof
CN103638237A (en) * 2013-12-18 2014-03-19 万小耀 External traumatic medicine composition, external traumatic medicinal oil and preparation method of medicinal oil

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CN103463381A (en) * 2013-09-25 2013-12-25 张国辉 Traditional Chinese medicine preparation for treating rheumatism bone pain and preparation method thereof
CN103638237A (en) * 2013-12-18 2014-03-19 万小耀 External traumatic medicine composition, external traumatic medicinal oil and preparation method of medicinal oil

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306650A (en) * 2014-11-02 2015-01-28 刘秋云 Drug for curing pathological fracture and preparation method
KR101914202B1 (en) * 2017-06-26 2018-11-01 재단법인 경기도경제과학진흥원 Composition for treating, preventing or alleviating bone diseases comprising extract of edgeworthia papyrifera

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Application publication date: 20140813