CN104127804A - Traditional Chinese medicine capable of treating diabetic foot ulcer - Google Patents
Traditional Chinese medicine capable of treating diabetic foot ulcer Download PDFInfo
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- CN104127804A CN104127804A CN201410310449.8A CN201410310449A CN104127804A CN 104127804 A CN104127804 A CN 104127804A CN 201410310449 A CN201410310449 A CN 201410310449A CN 104127804 A CN104127804 A CN 104127804A
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Abstract
The invention relates to a traditional Chinese medicine capable of treating diabetic foot ulcer, which comprises the following medicinal materials by weight: 12 parts of hollow wood, 8 parts of physalis angulata fruit, 10 parts of prickly poppies, 15 parts of chun stephanotis, 5 parts of gynura japonica, 12 parts of zingiberaceae Curcuma zedoaria, 14 parts of Hubei Malus spectabilis, 9 parts of caulophyllum robustum, 6 parts of tiarella polyphylla, 14 parts of froggrass, 10 parts of ternstroemia gymnanthera flower, 12 parts of pungent oleaster root, 10 parts of cathay begonia and 15 parts of whorlleaf stonecrop herb. Clinics and experiments show that the traditional Chinese medicine is effectively capable of treating diabetic foot ulcer.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of diabetic foot ulcer.
Background technology
Diabetic foot ulcer mainly refers to the diabetic at initial stage, does not occur the crowd of peripheral neuropathy and peripheral angiopathy, has but occurred that foot infects as symptoms such as the foot that paronychia, beriberi infection etc. caused infect, suppurates, festers.Primary disease is one of severe complication of diabetes, and the each layer tissue of patient from skin to B&J all can be got involved, and the gangrene of part or full foot can occur severe patient, needs amputation.Therefore, diabetic foot ulcer is that diabetics is disabled, lethal main cause.Along with sharply increasing of onset diabetes rate in recent years, the sickness rate of diabetic foot ulcer also significantly increases, and treatment diabetic foot ulcer is clinical thorny problem, at present, still lacks the obvious medicine of curative effect for the treatment of diabetic foot ulcer both at home and abroad.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Hollow wood [source] medical material Ji Yuan: be stem and leaf or the root of caprifoliaceae plant Herba Leycesteriae formosae and narrow calyx Herba Leycesteriae formosae.Latin plant animal mineral name: Leycesria formosa Wall.var.stenosepala Rehd. gathers and stores: stem and leaf summer, autumn gather, and root all can be excavated the whole year, all using fresh herb or cutting are dried.[nature and flavor] bitter in the mouth; Cool in nature.The heat clearing away of [function cures mainly] dampness removing; Promoting blood circulation and hemostasis.Main jaundice due to damp-heat; Rheumatic arthralgia; Asthma; Menoxenia; Traumatic hemorrhage; Cystitis; Fracture and injury.[usage and dosage] is for oral administration: decoct soup, 9-15g; Or steep in wine.External: appropriate, smash deposited, or decoction being used as a lotion.
Fructus Physalis Pubescentis [source] medical material Ji Yuan: be the fruit of plant of Solanaceae Herba Physalis pubescentis.Latin plant animal mineral name: Physalis pubescens L. gathers and stores: gather when fruit maturation autumn, using fresh herb or dry.[nature and flavor] sour in the mouth: property is flat.[function cures mainly] removing toxic substances; Dampness removing.Cardinal teeth pain; Pemphigus; Furuncle.[usage and dosage] is for oral administration: decoct soup, 6-9g.External: appropriate, smash juice and be coated with.
Argemone mexicana L. [source] medical material Ji Yuan: be the seed of bloodroot Argemone mexicana L. ArgemonemexicanaL..Latin plant animal mineral name: Argemone mexicana L. gathers and stores: adopt lower fruit when fruit maturation late summer, dries, and crushes, and removes shell, gets seed.[function cures mainly] cathartic; Emetic; Removing toxic substances; Pain relieving.Main constipation; Colic; Toothache; Syphilis.[usage and dosage] is for oral administration: decoct soup 2-4g.
Stephanotis chunii Tsiang [source] medical material Ji Yuan: be leaf or the root of the black climing rattan of dicotyledon medicine asclepiadaceae plant Stephanotis chunii Tsiang.Latin plant animal mineral name: Stephanotis chunii Tsiang gathers and stores: picking leaves in summer, dry; Uproot autumn, cleans, and section, dries.[nature and flavor] sweet in the mouth; Pungent; Warm in nature.[return through] liver; Kidney channel.[function cures mainly] enriches blood; Invigorate blood circulation; Stimulating milk secretion.Main menoxenia; Dysmenorrhea; Puerperal blood deficiency, hypogalactia.[usage and dosage] is for oral administration: decoct soup, 6-15g.
Chrysanthemum leaf Radix Notoginseng [source] is Compositae Herba Senecionis Chrysanthemoidis platymiscium Herba Senecionis Chrysanthemoidis Gynura segetum (Lour.) Merr., with root or all herbal medicine.Autumn and winter uproot, and remove residual stem, fibrous root and earth and dry.Xia Qiucai herb, cleans using fresh herb or dry.[nature and flavor] sweet, micro-hardship, temperature.The hemostasis of [function cures mainly] dissipating blood stasis, removing toxic substances and promoting subsidence of swelling.For spitting blood, epistaxis, hematuria, has blood in stool, dysfunctional uterine hemorrhage, postnatal blood stasis stomachache, Kaschin-Beck disease; Traumatic injury is controlled in external, carbuncle furuncle infections, venom, traumatic hemorrhage.[usage and dosage] 1～3 money; Suitable amount used externally, fresh goods is mashed deposited affected part.
Evil mind Rhizoma Zingiberis Recens [source] medical material Ji Yuan: be the rhizome of zingiberaceous plant evil mind Rhizoma Zingiberis Recens.Latin plant animal mineral name: Curcuma caesia Roxb. gathers and stores: summer, autumn gather, and removes stem and leaf and fibrous root, cleans, and using fresh herb or section are dried.[nature and flavor] bitter in the mouth; Pungent; Warm in nature.[function cures mainly] expelling wind and removing dampness; Reducing swelling and alleviating pain.Main air pain of dampness syndrome; Chest and abdomen swelling and pain; Puerperal lumbago; Wind syndrome of head pain; Traumatic injury.[usage and dosage] is for oral administration: decoct soup, 9-15g; Or infusing drugs in wine.External: appropriate, fresh goods is mashed, outer putting on the skin made in rectification popular.
Hubei Chinese flowering crabapple root [source] medical material Ji Yuan: be the root of Qiang Wei section plant Hubei Chinese flowering crabapple.Latin plant animal mineral name: Malus hupehensis (Pamp.) Rehd. gathers and stores: summer, autumn excavate, cleans, section, using fresh herb or dry.[function cures mainly] promoting blood circulation to remove obstruction in the collateral.Main traumatic injury.[usage and dosage] is for oral administration: decoct soup, fresh goods 60-90g.External: appropriate, grind into powder, dress.
Radix Caulophylli [source] medical material Ji Yuan: be root and the rhizome of Berberidaceae plant Radix Caulophylli.Latin plant animal mineral name: Caulophyllum robustum Maxim. gathers and stores: summer, autumn excavate, and removes stem and leaf, earth, cleans, and dries.[nature and flavor] are pungent; Bitter; [return through] warm in nature liver; Stomach.[function cures mainly] promoting blood circulation to remove blood stasis; Expelling wind and removing dampness; Promoting the circulation of QI to relieve pain.Main menoxenia; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; The cold pain of gastral cavity abdomen; Traumatic injury, rheumatic arthralgia.[usage and dosage] is for oral administration: decoct soup, 3-15g; Or infusing drugs in wine; Or grind into powder.
Herba tiarellae polyphyllae [source] medical material Ji Yuan: be the herb of saxifragaceae plant Herba tiarellae polyphyllae.Latin plant animal mineral name: Tiarella polyphylla D.Don[nature and flavor] hardship; Cold; Nontoxic.[return through] lung meridian.[function cures mainly] heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Main furuncle, nameless gall, cough, asthma, hepatitis, traumatic injury.[usage and dosage] is for oral administration: decoct soup, 9-15g; Or infusing drugs in wine.External is mashed.
Salicornia Bigelovii Torr. [source] medical material Ji Yuan: be the herb of chenopod salicornia europaeal.Latin plant animal mineral name: Salicornia europaeaL.[S.europaeaL.var.herbaceaL.; S.herbaceaL.] gather and store: gathering in herb summer, clean and dry.[function cures mainly] suppressing the hyperactive liver; Diuresis; Blood pressure lowering.Main hypertension; Headache.[usage and dosage] is for oral administration: decoct soup, 9-15g.
Pachydermia fragrant flower [source] medical material Ji Yuan: be the flower of plant of theaceae Ternstroemia gymnanthera.Latin plant animal mineral name: Ternstroemia gymnanthera (Wight etArn.) Sprague[Cleyera gymnanthera Wight et Arn.] to gather and store: the 7-8 month gathers, using fresh herb or dry.[function cures mainly] killing parasites for relieving itching.Main scabies pruritus.[usage and dosage] external: appropriate, mash external application or wipe affected part.
Radix Elaeagni [source] is the root of Elaeangnaceae plant Fructus Elaeagni Elaeagnus pungens Thunb..Latin plant animal mineral name: Elaeagnus pungens Thunb. gathers and stores: summer, autumn excavate, cleans, and section is dried.[nature and flavor] bitter in the mouth; Acid; Property is put down.[return through] lung; Spleen channel.[function cures mainly] promoting blood circulation and hemostasis; Expelling wind and removing dampness; Relieving cough and asthma; Removing toxic substances sore.Main taste blood; Spitting of blood; Have blood in stool; Menorrhagia; Rheumatic arthritis; Jaundice; Edema; Dysentery; Infantile malnutrition: cough with asthma; Laryngopharynx swelling and pain; Skin ulcer scabies; Injury from falling down.
Herba Begoniae Cathyanae [source] is the herb of Begoniaceae plant floral leaf Flos Begoniae Evansianae.Latin plant animal mineral name: Begonia cathayana Hemsl. gathers and stores: can adopt the whole year, using fresh herb or dry.[nature and flavor] sour in the mouth; Puckery, cool in nature.[function cures mainly] lung heat clearing order is coughed; Removing toxic substances dissipating blood stasis for subsidence of swelling.Main cough due to lung-heat; Tonsillitis; Pertussis, carbuncle pyogenic infections from tumour or sore; Burn and scald; Traumatic injury congestive edema.[usage and dosage] external: decoct soup, 6-9g.External: appropriate; Fresh goods is smash deposited; Or smash juice be coated with; Or dry product grind into powder spread deposited.
Herba Hylothelephii Verticillati [source] is the herb of crassulaceae plants wheel blade Herba hylotelephii erythrosticti.Summer, autumn adopt, and clean using fresh herb.[nature and flavor] bitterness, flat.[function cures mainly] removing toxic substances, detumescence, hemostasis.Control wound, innominate toxic swelling, Serpentis stings and scorpion sting.[usage and dosage] external: smash and apply or the painting of strand juice.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of diabetic foot ulcer, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective treatment diabetic foot ulcer.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of diabetic foot ulcer, it is characterized in that, be prepared from by the medical material of following weight proportion: hollow wooden 12 parts, 10 parts of 8 parts of Fructus Physalis Pubescentis, Argemone mexicana L., 15 parts of Stephanotis chunii Tsiangs, 5 parts of chrysanthemum leaf Radix Notoginseng, 12 parts of evil mind Rhizoma Zingiberis Recens, 14 parts of Hubei Chinese flowering crabapple roots, 9 parts of Radix Caulophyllis, 6 parts of Herba tiarellae polyphyllaes, 14 parts of Salicornia Bigelovii Torr.s, 10 parts, pachydermia fragrant flower, 12 parts of Radix Elaeagnis, 10 parts of Herba Begoniae Cathyanaes, 15 parts of Herba Hylothelephii Verticillatis.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
87 routine diabetic foot ulcer inpatients are collected, wherein male 52 examples, female's 35 examples between year June altogether in inventor in March, 2010-2012, all belong to 1～3 grade of patient in Wagner staging, age 55-70 year, diabetes average course of disease 1-8, average 28 days of the diabetic foot course of disease.Patient is divided at random: treatment group 45 examples, matched group 42 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
2.1 treatment measures: 75 routine patients are all to the blood sugar lowering such as diet control, insulin, the Comprehensive Treatments such as effective antibiotics and debridement, Local treatment
2.2 matched groups: on the basis of Comprehensive Treatment, patient gives cilostazol table, methyl vitamin B
12oral, 2 times/day, 28 days courses for the treatment of.
2.3 treatment groups: on the basis of Comprehensive Treatment, the capsule that oral the present invention makes according to specific embodiment 1, sooner or later respectively once, 28 days courses for the treatment of.
3, efficacy determination and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: ulcer area healing or substantially healing.Effective: ulcer area is obviously dwindled, be less than 50% before treatment, merocrine secretion's thing reduces, and slough major part comes off or part granulation new life.Effective: ulcer area is dwindled, but still be greater than 50% before treatment.Invalid: ulcer area is without obviously dwindling, and secretions is without obvious minimizing, local without significant change or deterioration person.
3.2 treatment statistical results are in table 1.
Table 1 liang group curative effect comparison
Note: through x
2inspection, matched group and treatment group have significant difference (P < 0.05), show that treatment group is better than matched group
Visible, the medicine that the present invention makes can safe and effective treatment diabetic foot ulcer.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: hollow wooden 12 grams, 10 grams of 8 grams of Fructus Physalis Pubescentis, Argemone mexicana L., 15 grams of Stephanotis chunii Tsiangs, 5 grams of chrysanthemum leaf Radix Notoginseng, 12 grams of evil mind Rhizoma Zingiberis Recens, 14 grams of Hubei Chinese flowering crabapple roots, 9 grams of Radix Caulophyllis, 6 grams of Herba tiarellae polyphyllaes, 14 grams of Salicornia Bigelovii Torr.s, 10 grams, pachydermia fragrant flower, 12 grams of Radix Elaeagnis, 10 grams of Herba Begoniae Cathyanaes, 15 grams of Herba Hylothelephii Verticillatis, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of diabetic foot ulcer.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: hollow wooden 12 grams, 10 grams of 8 grams of Fructus Physalis Pubescentis, Argemone mexicana L., 15 grams of Stephanotis chunii Tsiangs, 5 grams of chrysanthemum leaf Radix Notoginseng, 12 grams of evil mind Rhizoma Zingiberis Recens, 14 grams of Hubei Chinese flowering crabapple roots, 9 grams of Radix Caulophyllis, 6 grams of Herba tiarellae polyphyllaes, 14 grams of Salicornia Bigelovii Torr.s, 10 grams, pachydermia fragrant flower, 12 grams of Radix Elaeagnis, 10 grams of Herba Begoniae Cathyanaes, 15 grams of Herba Hylothelephii Verticillatis, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of diabetic foot ulcer.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: hollow wooden 12 grams, 10 grams of 8 grams of Fructus Physalis Pubescentis, Argemone mexicana L., 15 grams of Stephanotis chunii Tsiangs, 5 grams of chrysanthemum leaf Radix Notoginseng, 12 grams of evil mind Rhizoma Zingiberis Recens, 14 grams of Hubei Chinese flowering crabapple roots, 9 grams of Radix Caulophyllis, 6 grams of Herba tiarellae polyphyllaes, 14 grams of Salicornia Bigelovii Torr.s, 10 grams, pachydermia fragrant flower, 12 grams of Radix Elaeagnis, 10 grams of Herba Begoniae Cathyanaes, 15 grams of Herba Hylothelephii Verticillatis, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and to granulate according to this area common process, packaging, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of diabetic foot ulcer.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. treat the Chinese medicine of diabetic foot ulcer for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: hollow wooden 12 parts, 10 parts of 8 parts of Fructus Physalis Pubescentis, Argemone mexicana L., 15 parts of Stephanotis chunii Tsiangs, 5 parts of chrysanthemum leaf Radix Notoginseng, 12 parts of evil mind Rhizoma Zingiberis Recens, 14 parts of Hubei Chinese flowering crabapple roots, 9 parts of Radix Caulophyllis, 6 parts of Herba tiarellae polyphyllaes, 14 parts of Salicornia Bigelovii Torr.s, 10 parts, pachydermia fragrant flower, 12 parts of Radix Elaeagnis, 10 parts of Herba Begoniae Cathyanaes, 15 parts of Herba Hylothelephii Verticillatis.
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| CN201410310449.8A CN104127804A (en) | 2014-06-30 | 2014-06-30 | Traditional Chinese medicine capable of treating diabetic foot ulcer |
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| CN201410310449.8A CN104127804A (en) | 2014-06-30 | 2014-06-30 | Traditional Chinese medicine capable of treating diabetic foot ulcer |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106509903A (en) * | 2016-12-13 | 2017-03-22 | 青岛嘉瑞生物技术有限公司 | Salicornia europaea health-care oral liquid having effects of treating diabetes |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926872A (en) * | 2009-05-08 | 2010-12-29 | 韩会民 | Chinese medicinal detoxifying myo-regeneration paste for treating diabetic foot ulcer and preparation method thereof |
| CN102319327A (en) * | 2011-10-11 | 2012-01-18 | 张俊瑕 | Traditional Chinese medicine for internally and externally treating diabetic foot |
| CN103479883A (en) * | 2013-09-18 | 2014-01-01 | 刘聪 | Tissue regeneration promoting ulcer recovering oil used for treating diabetic foot ulcer |
-
2014
- 2014-06-30 CN CN201410310449.8A patent/CN104127804A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926872A (en) * | 2009-05-08 | 2010-12-29 | 韩会民 | Chinese medicinal detoxifying myo-regeneration paste for treating diabetic foot ulcer and preparation method thereof |
| CN102319327A (en) * | 2011-10-11 | 2012-01-18 | 张俊瑕 | Traditional Chinese medicine for internally and externally treating diabetic foot |
| CN103479883A (en) * | 2013-09-18 | 2014-01-01 | 刘聪 | Tissue regeneration promoting ulcer recovering oil used for treating diabetic foot ulcer |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106509903A (en) * | 2016-12-13 | 2017-03-22 | 青岛嘉瑞生物技术有限公司 | Salicornia europaea health-care oral liquid having effects of treating diabetes |
| CN106509903B (en) * | 2016-12-13 | 2019-12-06 | 青岛嘉瑞生物技术有限公司 | salicornia herbacea oral liquid with effect of treating diabetes |
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Application publication date: 20141105 |