CN104189514A - Lymphatic tuberculosis resolving hard lump and eliminating phlegm preparation and preparation method thereof - Google Patents
Lymphatic tuberculosis resolving hard lump and eliminating phlegm preparation and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a lymphatic tuberculosis resolving hard lump and eliminating phlegm preparation and a preparation method thereof. The preparation is prepared by the following bulk drugs in part by weight: 5 to 12 parts of gleditschia horrida wood veneer, 6 to 15 parts of chrysanthemum indicum, 3 to 9 platycodon root, 10 to 20 parts of red sage root, 6 to 10 parts of scutellaria root, 8 to 12 parts of cyperirhizome, 6 to 9 parts of annual fleabane, 6 to 15 parts of fleece-flower root, 18 to 32 parts of Bridelia fordii Hemsl, 15 to 25 parts of selfheal spike, 6 to 12 parts of forsythia fruit, 8 to 16 parts of pangolin meat, and 8 to 16 parts of buttercup root. The preparation has obvious effect and does not have any toxic and side effects.
Description
Technical field
The present invention relates to Chinese medicine field, particularly relate to a kind of lymphoid tuberculosis softening the hard mass preparation and preparation method thereof that eliminates the phlegm.
Background technology
Lymphoid tuberculosis, is the malicious block organization that is embodied in flesh table, is to be become by the scorchingly hot poison cohesion of expectorant of liver lung two aspects.Lymphoid tuberculosis is a kind of common surgical diseases occurring between neck axil, and its clinical characters is in neck side, under jaw or prolong and supraclavicular fossa, from the beginning of time tuberculosis be bean, color of the leather is constant, feels no pain, enlargement gradually later, merges bunchiness mutually, for a long time diabrosis, pus is rare clearly, accompany and lose floccule, form sinus tract, do not close up for a long time, this ulceration of healing, does not prolongedly heal.Therefore forefathers to primary disease have the saying of " three difficulties " (be locomorphic stage difficulty disappear, become difficult bursting of pus phase, difficult closing in of ulceration phase), the syndrome such as its severe one is weak with hectic fever due to YIN-deficiency, hectic fever, night sweat, become thin, Chinese medicine is called scrofula.Lymphoid tuberculosis, according to site of pathological change, mainly contains following several: (1) cervical lymph node core: this is the most common in lymphoid tuberculosis, and women is more than male.According to Japanese statistics, site of pathological change is taking right side as common.The traditional Chinese medical science thinks, primary disease is hindered by feelings will, depression of liver-QI, spleen deficiency generating phlegm.Stagnation of liver-QI is heat-transformation, and expectorant heat is fought mutually, respects the venation in neck, forms scrofula.Also factor body weakness, deficiency of YIN of both the lung and kidney, causes cloudy losing and hyperactivity of fire, and phlegm-fire condenses and forms scrofula.(2) axillary region lymphoid tuberculosis: primary disease is clinical more rare.Patient is the lymphadenectasis of main suit's axillary region often, and pain is medical; Also have and in the time of chest X-ray, find that calcification is arranged at axillary region or thoracic wall top.(3) pars inguinalis lymphoid tuberculosis: pars inguinalis lymphadenectasis, many wounds from lower limb or external genital.But tulase is sent out to whole body, also can occur once in a while.Start can be the only swelling with mild pain, as positive treatment not, can be from bursting.
Lymphoid tuberculosis belongs to worldwide persistent ailment, is the generally acknowledged refractory disease of medical circle.This disease complicated clinical manifestation, relapse rate is high, and doctor trained in Western medicine lacks specially controls medicine, and the traditional Chinese medical science is not fixed good recipe, cannot ensure curative effect.A lot of Medical monographs are all decided to be lymphoid tuberculosis " intractable surgery diseases ", only depend on doctor trained in Western medicine to be difficult to rehabilitation, only depend on the traditional Chinese medical science to be also difficult to eradicate.Because current doctor trained in Western medicine is not yet developed the scrofulous special medicament for the treatment of, in treatment, generally adopt the phthisical therapeutic regimen for the treatment of to carry out chemotherapy, effect is unsatisfactory.These antituberculotics toxic and side effects are larger, and long-term taking easily causes the diseases such as hepatopathy.If irregular medication, also can produce drug resistance, drug resistance, make chemotherapy invalid, form intractable tuberculosis.For abscess, diabrosis, fistula type lymphoid tuberculosis, because of lymphoid tissue and blood vessel, neural weave in, operative treatment easily causes that wound can not heal, multiple relapse.Chinese traditional treatment lymphoid tuberculosis, is all generally taking external application as main, and through sweat gland of skin and blood capillary osmotic absorption, the course of disease is touching, poor effect.
Application publication number CN 102188615 A(application numbers 201110111758.9) Chinese patent literature a kind of scrofulous Therapeutic Method is disclosed, it is that the mode of pasting medicine by umbilical part is treated lymphoid tuberculosis, its medicine is by Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati, Pseudobulbus Cremastrae Seu Pleiones, Thallus Laminariae (Thallus Eckloniae), Sargassum, Radix Scrophulariae, Radix Angelicae Sinensis, the Radix Astragali, Pericarpium Citri Reticulatae, Semen Sinapis Albae, Scolopendra, Scorpio composition, its weight proportion: Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati, Pseudobulbus Cremastrae Seu Pleiones, Thallus Laminariae (Thallus Eckloniae), Sargassum, Radix Scrophulariae, Radix Angelicae Sinensis, the Radix Astragali, Pericarpium Citri Reticulatae, Semen Sinapis Albae, Scolopendra, Scorpio is 2: 2: 2: 1: 1: 1: 2: 1: 1: 1: 1: 1: 1.Application publication number CN 102380038 A(application numbers 201010269187.7) Chinese patent literature disclose one and treated scrofulous Chinese medicine formula and rad-hot needle therapy.Chinese medicine formula is: Scolopendra, Herba Violae, Radix Cirsii Japonici, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Forsythiae, Flos Lonicerae, Radix Bupleuri, Spica Prunellae, Sargassum, the Radix Astragali, Radix Angelicae Sinensis, Radix Platycodonis, Poria, Radix Asparagi, Radix Ranunculi Ternati, Herba Euphorbiae Helioscopiae.Its preparation method: use Chinese medicine compound preparation method.Rad-hot needle therapy: use Traditional Chinese Medicine rad-hot needle therapy.Application publication number CN 103656389 A(application numbers 201310587966.5) Chinese patent literature disclose one and treated scrofulous Chinese medicine composition, the weight portion of its constitutive material is: Rhizoma Sparganii 4-6, Fructus Arctii 2-4, Fructus Forsythiae 6-7, Endoconcha Sepiae 5-6, Radix Scrophulariae 3-5, Semen Strychni 2-4, Radix Kansui 3-5, ferrum bull 1-2, Radix Semiaquilegiae 3-4, tetrastigma hemsleyanum 5-7, Rhizoma Smilacis Glabrae 6-8, Radix viticis negundo 4-6, Herba Rubi parvifolii 1-2, Cortex Phellodendri 8-10, Folium Ricini 8-9, Herba cynodontis 4-6, Herba Houttuyniae 3-5, Spica Prunellae 2-4, Rhizoma Dioscoreae 10-15, Herba Hyperici Japonici 1-2, Sargassum 7-8, Radix Polygoni Multiflori 5-7, Indigo Naturalis 2-3 and Herba galinsogae parviflorae 1-2.
In a word, current modern doctor trained in Western medicine lacks treatment and scrofulously specially controls medicine, though the method treatments such as available antituberculotics can only be played retarding action, the course for the treatment of is very long, and delay is difficult, and rehabilitation rate is extremely low.And Chinese traditional treatment lymphoid tuberculosis is all generally taking external application as main, through sweat gland of skin and blood capillary osmotic absorption, the course of disease is touching, poor effect.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of short treating period, instant effect, without the lymphoid tuberculosis softening the hard mass of the recurrence preparation and preparation method thereof that eliminates the phlegm.This lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm is evident in efficacy and without any side effects.
Technical scheme of the present invention is:
The lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, takes off the primary raw material medicine of stating weight proportion and is prepared from: Fructus Gleditsia veneer 5-12 part, Herba Dendranthematis indici 6-15 part, Radix Platycodonis 3-9 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Scutellariae 6-10 part, Rhizoma Cyperi 8-12 part, Herba Erigerontis Annui 6-9 part, Radix Polygoni Multiflori 6-15 part, Dendrobium jenkinsii Wall ex Lindl． 18-32 part, Spica Prunellae 15-25 part, Fructus Forsythiae 6-12 part, Manitis meat 8-16 part, Radix Ranunculi Ternati 8-16 part.
The lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, preferred scheme is, takes off the primary raw material medicine of stating weight proportion and is prepared from: Fructus Gleditsia veneer 8-11 part, Herba Dendranthematis indici 9-12 part, Radix Platycodonis 4-7 part, Radix Salviae Miltiorrhizae 14-17 part, Radix Scutellariae 7.5-9 part, Rhizoma Cyperi 9-11 part, Herba Erigerontis Annui 6.5-8 part, Radix Polygoni Multiflori 8-11 part, Dendrobium jenkinsii Wall ex Lindl． 23-27 part, Spica Prunellae 17-22 part, Fructus Forsythiae 7-10 part, Manitis meat 9-12 part, Radix Ranunculi Ternati 10-14 part.
The lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, the scheme being more preferably is, takes off the primary raw material medicine of stating weight proportion and is prepared from: 10 parts of Fructus Gleditsia veneer, 11 parts, Herba Dendranthematis indici, 6 parts of Radix Platycodoniss, 15 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Scutellariaes, 9.5 parts of Rhizoma Cyperis, 7 parts of Herba Erigerontis Annuis, 9.5 parts of Radix Polygoni Multiflori, 25 parts of Dendrobium jenkinsii Wall ex Lindl．, 19 parts of Spica Prunellaes, 9 parts of Fructus Forsythiaes, 10 parts of Manitis meat, 12 parts of Radix Ranunculi Ternatis.
The present invention also provides the aforementioned lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm has been made to the preparation method of pharmaceutically acceptable decoction, powder, pill and thick paste agent.
The preparation method of described decoction is:
(1) Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are removed to impurity, after cleaning, put into terrine, soak 2.5-5 hour (preferably soaking 3.2 hours), amount of water is doubly (preferably 4.2 times) of 3-6.5 that add drug weight;
(2) first boil to boiling with big fire, after turn slow fire boiling 0.8-3 hour (preferably 2 hours), leach medicinal liquid;
(3) (talcous weight is 2-5 times of acacia wood tare weight amount to get Pulvis Talci; Preferably, talcous weight is 3 times of acacia wood tare weight amount), put in pot, make popular with moderate heat, add neat soap pod veneer, stir 0.5-2 hour (preferably 1.5 hours), take out, sieve removes Pulvis Talci, cool, pulverization, crosses 150-230 mesh sieve (preferred mistake 200 mesh sieves);
(4) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, and (consumption of vinegar is the 1/16-1/5 of Manitis meat weight to add vinegar; Preferably, the consumption of vinegar be Manitis meat weight 1/6), with slow fire fry 12-28 minute (preferably 18 minutes), taking-up cools, pulverization, cross 160-230 mesh sieve (preferred mistake 200 mesh sieves), obtain fine powder;
(5) step (3) and step (4) gained fine powder are joined in step (2) gained medicinal liquid, to obtain final product.
The preparation method of described powder is:
(1) Manitis meat is cleaned, put into boiling water pot and scald, pull clean shredding out, dry in the shade, by the Manitis meat pulverization drying in the shade, cross 180-230 mesh sieve (preferred mistake 210 mesh sieves), obtain fine powder;
(2) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are pulverized respectively, cross 170-250 mesh sieve (preferably 210 mesh sieves), obtain fine powder;
(3) by step (1) and step (2) gained fine powder mix homogeneously, obturage with paper wrapper, in 105-120 DEG C (preferably 110 DEG C) dry heat sterilization 3-4 hour (preferably 3.5 hours), be sealed in plastic bag, 5 grams every bag, to obtain final product.
The preparation method of described pill is:
(1) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, and (consumption of vinegar is the 1/14-1/2 of Manitis meat weight to add vinegar; Preferably, the consumption of vinegar be Manitis meat weight 1/4), with slow fire fry 18-40 minute (preferably 25 minutes), taking-up cools, pulverization, cross 150-180 mesh sieve (preferred mistake 160 mesh sieves), obtain fine powder;
(2) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are pulverized respectively, cross 140-200 mesh sieve (preferred mistake 160 mesh sieves), obtain fine powder;
(3), by step (1) and step (2) gained fine powder mix homogeneously, taking water as wetting agent, making diameter is that the preferred diameter of 2-6mm(is 3mm) little pill, be drying to obtain.
The preparation method of described thick paste agent is:
(1) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, and (consumption of vinegar is the 1/10-1/4 of Manitis meat weight to add vinegar; Preferably, the consumption of vinegar be Manitis meat weight 1/5), with slow fire fry 15-40 minute (preferably 22 minutes), taking-up cools, pulverization, cross 170-200 mesh sieve (preferred mistake 180 mesh sieves), obtain fine powder;
(2) Radix Polygoni Multiflori, Radix Scutellariae are pulverized respectively rough, the ethanol that is 50%-70% by mass concentration respectively (ethanol that preferred mass concentration is 60%) is made solvent, flood and after (preferably flooding 26 hours), carry out percolation in 20-30 hour, the collection liquid of filtering, reclaim ethanol, and evaporation and concentration to volume (by milliliter) be doubly (preferred evaporation and concentration to volume is 2.3 times of crude drug in whole weight) of 2.2-2.6 of crude drug in whole weight (by gram);
(3) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Rhizoma Cyperi, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are removed to impurity, after cleaning, put into terrine, add water (amount of water be add drug weight 3.6-5.8 doubly; Preferred amount of water is to add 4.5 times of drug weight), first boil to boiling with big fire, after turn slow fire boiling 0.8-3 hour (preferably 1.8 hours), leach medicinal liquid;
(4) step (2) gained concentrated solution and step (3) gained medicinal liquid are merged, then put into marmite and decoct 1.5-4 hour (preferably decocting 2.8 hours), obtain thick cream drug;
(5) get sugar refinery or refined honey join in the thick cream drug of step (4) gained (amount of sugar refinery or refined honey be thick paste shape drug weight 1.5-3.5 doubly; Preferably, the amount of sugar refinery or refined honey is 1.8 times of thick paste shape drug weight), then step (1) gained fine powder is added and mixed well, micro-refining, foam removal, seals and get final product in dress aseptic bottle.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Gleditsia veneer: base is former: be peel of stem and the root bark of pulse family Gleditsia plant Fructus Gleditsia.The property of medicine: pungent, temperature, nontoxic.Function cures mainly: detoxicating and resolving stagnation of pathogens, wind dispelling insecticide.Cure mainly lymphoid tuberculosis, innominate toxic swelling, rheumatic ostalgia, scabies, malignant boil.
Herba Dendranthematis indici: base is former: be root or the herb of Compositae Dendranthema Herba Dendranthematis indici or lavandulaleaf dendranthema herb.Chemical analysis: Herba Dendranthematis indici herb is containing volatile oil, linarin, the glycoside of luteolin, Chrysanthemin, chrysanthemaxanthin, polysaccharide, Coumarins, yejuhua lactone.In volatile oil, be mainly camphene, Camphora, Eucarvone etc.The property of medicine: bitter, acrid, cold.Return liver, heart channel.Function cures mainly: heat-clearing and toxic substances removing, improving eyesight.Cure mainly flu, dysentery, carbuncle, furuncle, conjunctival congestion and swelling pain, dizzy, scrofula, eczema.
Radix Platycodonis: base is former: base is former: this product is the root of dicotyledon campanulaceae Radix Platycodonis.The property of medicine: bitter, pungent, flat.Return lung meridian.Function cures mainly: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.
Radix Salviae Miltiorrhizae: base is former: be the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.The property of medicine: hardship, is slightly cold.GUIXIN, Liver Channel.Function cures mainly: stasis-dispelling and pain-killing, and promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Radix Scutellariae: base is former: be the dry root of labiate Radix Scutellariae.The property of medicine: hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Function cures mainly: heat clearing and damp drying, and eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Rhizoma Cyperi: base is former: be the dry rhizome of sedge dried tuber.The property of medicine: pungent, micro-hardship, micro-sweet, flat.Return liver, spleen, tri-jiao channel.Function cures mainly: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, colic of cold type stomachache, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Herba Erigerontis Annui: base is former: be the herb of feverfew Herba Erigerontis Annui.Chemical analysis: herb contains Quercetin, the intoxicated sour glycoside of apigenin-7-glucose, apigenin containing pyromeconic acid, flower.Pharmacological action: the water extract after stem, leaf wash with petroleum ether, ether, chloroform, has hypoglycemic activity.The dull and stereotyped paper disk method of 100% decoct, has inhibitory action to staphylococcus aureus, shigella.The property of medicine: sweet, bitter, cold.Return stomach, large intestine channel.Function cures mainly: the antidiarrheal that helps digestion, heat-clearing and toxic substances removing, preventing the attack (or recurrence) of malaria.Main dyspepsia, gastroenteritis, gingivitis, malaria, venom.
Radix Polygoni Multiflori: base is former: be the dried root of polygonum multiflorum thunb.Nature and flavor: bitter, sweet, puckery, temperature.Return liver, the heart, kidney channel.Function cures mainly: removing toxic substances, eliminating carbuncle, loosening bowel to relieve constipation.For scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; Hyperlipidemia.
Dendrobium jenkinsii Wall ex Lindl．: base is former: for the stem of dicotyledon medicine orchid Dendrobium jenkinsii Wall ex Lindl． (shrimp ridge Herba Dendrobii), with all herbal medicine.The property of medicine: sweet, light, flat.Attach to the lung and stomach meridians.Function cures mainly: nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.For laryngopharynx swelling and pain, oral erosion, quench one's thirst, xerostomia, thirsty etc., cough, expectoration, asthma, the deficiency of YIN etc.
Spica Prunellae: base is former: be the dry fruit ear of labiate Spica Prunellae.The property of medicine: pungent, bitter, cold.Return liver, gallbladder meridian.Function cures mainly: relieves inflammation or internal heat, and improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, and goiter, acute mastitis swells and ache, thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Fructus Forsythiae: base is former: be the dry fruit of Oleaceae plants Fructus Forsythiae.The property of medicine: hardship, is slightly cold.Return lung, the heart, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease is from the beginning of, warm joining the army, high hot excessive thirst, coma is sent out speckle, pyretic stranguria urine retention.
Manitis meat: base is former: be the meat of Manidae Manis animal Manitis.The property of medicine: sweet, puckery, flat.Function cures mainly: nourishing YIN and clearing away heat, detoxicating and resolving stagnation of pathogens.Cure mainly weakness due to chronic disease, the enuresis, scrofula, leprosy.
Radix Ranunculi Ternati: base is former: be the dried root of the little Herba Ranunculi Japonici of ranunculaceae plant.The property of medicine: sweet, acrid, warm.Return liver, lung meridian.Function cures mainly: eliminating stagnation, detumescence.Do not burst for scrofula; Tuberculous lymphadenitis.
Lymphoid tuberculosis softening the hard mass of the present invention eliminates the phlegm preparation according to Chinese medical discrimination theory, prescription science, taking convenience.In addition, excellent results of the present invention also shows:
1, melt nourishing YIN and clearing away heat, eliminate the phlegm, hard masses softening and resolving, promoting QI circulation for relieving depression, how parasite killing detoxifies, plays altogether not the bursting of the core that disappears, the broken effect of scrofula, so lymphoid tuberculosis phase no matter all can treat, can obtain good efficacy.
2, rapidly, therapeutic effect is obvious in effect;
3, better tolerance;
4, without any side effects;
5, short treating period, instant effect, without recurrence.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
embodiment 1the lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, the primary raw material medicine of getting following weight is prepared from: Fructus Gleditsia veneer 5g, Herba Dendranthematis indici 6g, Radix Platycodonis 3g, Radix Salviae Miltiorrhizae 10g, Radix Scutellariae 6g, Rhizoma Cyperi 8g, Herba Erigerontis Annui 6g, Radix Polygoni Multiflori 6g, Dendrobium jenkinsii Wall ex Lindl． 18g, Spica Prunellae 15g, Fructus Forsythiae 6g, Manitis meat 8g, Radix Ranunculi Ternati 8g.
The eliminate the phlegm preparation method of preparation thick paste agent of lymphoid tuberculosis softening the hard mass is:
(1) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, adds vinegar (consumption of vinegar be Manitis meat weight 1/10), fries 15 minutes with slow fire), taking-up cools, and pulverization is crossed 170 mesh sieves, obtains fine powder;
(2) Radix Polygoni Multiflori, Radix Scutellariae are pulverized respectively rough, make solvent with the ethanol that mass concentration is 50% respectively, flood and carry out percolation after 20 hours, collect the liquid of filtering, reclaim ethanol, and evaporation and concentration to volume (by milliliter) is 2.2 times of crude drug in whole weight (by gram);
(3) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Rhizoma Cyperi, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are removed to impurity, after cleaning, put into terrine, adding water, (amount of water is to add 3.6 times of drug weight, first boil to boiling with big fire, after turn slow fire boiling 0.8 hour, leach medicinal liquid;
(4) step (2) gained concentrated solution and step (3) gained medicinal liquid are merged, then put into marmite and decoct 1.5 hours, obtain thick cream drug;
(5) get sugar refinery and join (amount of sugar refinery is 1.5 times of thick paste shape drug weight) in the thick cream drug of step (4) gained, then step (1) gained fine powder is added and mixed well, micro-refining, foam removal, seals and get final product in dress aseptic bottle.
The instructions of taking of thick paste agent of the present invention: every day three times, each 20 grams.
embodiment 2the lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, the primary raw material medicine of getting following weight is prepared from: Fructus Gleditsia veneer 12g, Herba Dendranthematis indici 15g, Radix Platycodonis 9g, Radix Salviae Miltiorrhizae 20g, Radix Scutellariae 10g, Rhizoma Cyperi 12g, Herba Erigerontis Annui 9g, Radix Polygoni Multiflori 15g, Dendrobium jenkinsii Wall ex Lindl． 32g, Spica Prunellae 25g, Fructus Forsythiae 12g, Manitis meat 16g, Radix Ranunculi Ternati 16g.
The eliminate the phlegm preparation method of preparation decoction of lymphoid tuberculosis softening the hard mass is:
(1) Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are removed to impurity, after cleaning, put into terrine, soak and soak 3.2 hours, amount of water is to add 4.2 times of drug weight;
(2) first boil to boiling with big fire, after turn slow fire boiling 2 hours, leach medicinal liquid;
(3) get Pulvis Talci (talcous weight is 3 times of acacia wood tare weight amount), put in pot, make popular with moderate heat, add neat soap pod veneer, stir 1.5 hours, take out, sieve removes Pulvis Talci, cools, and pulverization, crosses 200 mesh sieves;
(4) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, adds vinegar (consumption of vinegar be Manitis meat weight 1/6), fries 18 minutes with slow fire, and taking-up cools, and pulverization is crossed 200 mesh sieves, obtains fine powder;
(5) step (3) and step (4) gained fine powder are joined in step (2) gained medicinal liquid, to obtain final product.
model case one:zhao XX, female, 36 years old.The patient body sleepiness of becoming thin, hectic fever night sweat 5 months, is diagnosed as lymphoid tuberculosis.Take Chinese medicine and western medicine curative effect not aobvious.Closely January, health was become thin, brothers' heart heating at night, and dry mouth and throat, night sweat is weak, with cough and expectoration.Check that right side cervical region can touch 3 × 4cm lump, 4 × 4cm lump can be touched in right oxter, red tongue, and thready pulse is number slightly.Take the present embodiment gained lymphoid tuberculosis softening the hard mass preparation decoction that eliminates the phlegm, every day twice, each 250mL.Taking 5 days lumps disappears.Continue to take 5 days, all diseases all disappear, and tuberculin test is turned out cloudy, recovery from illness.Follow up a case by regular visits to so far, without recurrence.
embodiment 3the lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, the primary raw material medicine of getting following weight is prepared from: Fructus Gleditsia veneer 8g, Herba Dendranthematis indici 9g, Radix Platycodonis 4g, Radix Salviae Miltiorrhizae 14g, Radix Scutellariae 7.5g, Rhizoma Cyperi 9g, Herba Erigerontis Annui 6.5g, Radix Polygoni Multiflori 8g, Dendrobium jenkinsii Wall ex Lindl． 23g, Spica Prunellae 17g, Fructus Forsythiae 7g, Manitis meat 9g, Radix Ranunculi Ternati 10g.
The eliminate the phlegm preparation method of preparation powder of lymphoid tuberculosis softening the hard mass is:
(1) Manitis meat is cleaned, put into boiling water pot and scald, pull clean shredding out, dry in the shade, by the Manitis meat pulverization drying in the shade, cross 210 mesh sieves, obtain fine powder;
(2) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are pulverized respectively, 210 mesh sieves, obtain fine powder;
(3) by step (1) and step (2) gained fine powder mix homogeneously, obturage with paper wrapper, in 110 DEG C of dry heat sterilizations 3.5 hours, be sealed in plastic bag, 5 grams every bag, to obtain final product.
model case two:once XX, female, 38 years old.Suffer from the tuberculosis of cervical lymph nodes more than 5 years, once failed to respond to any medical treatment with antituberculosis drugs thing.Examine quarter: there are do not burst 3 pieces of persons of lymph at neck place, left side, and shape is as a string of bells hung round the neck, red and swollen heat pain; 1 piece, right side is routed, has transudate.Take the present embodiment gained lymphoid tuberculosis softening the hard mass preparation powder that eliminates the phlegm, every day twice, each 5 grams, boiled water is taken after mixing it with water.Take 15 days, all diseases disappear, recovery from illness.Follow up a case by regular visits to and have no recurrence.
embodiment 4the lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, the primary raw material medicine of getting following weight is prepared from: Fructus Gleditsia veneer 11g, Herba Dendranthematis indici 12g, Radix Platycodonis 7g, Radix Salviae Miltiorrhizae 17g, Radix Scutellariae 9g, Rhizoma Cyperi 11g, Herba Erigerontis Annui 8g, Radix Polygoni Multiflori 11g, Dendrobium jenkinsii Wall ex Lindl． 27g, Spica Prunellae 22g, Fructus Forsythiae 10g, Manitis meat 12g, Radix Ranunculi Ternati 14g.
The eliminate the phlegm preparation method of preparation pill of lymphoid tuberculosis softening the hard mass is:
(1) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, adds vinegar (consumption of vinegar be Manitis meat weight 1/4), fries 25 minutes with slow fire, and taking-up cools, and pulverization is crossed 160 mesh sieves, obtains fine powder;
(2) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are pulverized respectively, cross 160 mesh sieves, obtain fine powder;
(3) by step (1) and step (2) gained fine powder mix homogeneously, taking water as wetting agent, making diameter is the little pill of 3mm, is drying to obtain.
model case three:yellow XX, female, 54 years old.Main suit: because cervical lymph node swells and ache, heating, more than 20 days.History of present illness: patient realizes that without obvious inducement cervical lymph node swells and ache before sky more than 20, the heat that occurs together, without cough and expectoration, without stomachache, suffers from diarrhoea.Once arrive local hospital medical, applied dexamethasone, the medicines such as ceftriaxone, symptom takes a turn for the better and leaves hospital.Before 4 days, patient starts to occur heating, cough and expectoration, and middle epigastrium persistence dull pain, without diarrhoea, without nausea and vomiting, without night sweat, for further treatment is gone to see a doctor.Physical examination: T38.6 DEG C, P100bpm, R24bpm, Bp130/90mmHg, mind is clear, physical examination cooperation, whole skin and mucosa have no xanthochromia, cervical region, several enlarged lymph nodes, tenderness can be touched in groin and oxter.Be diagnosed as lymphoid tuberculosis.Take the present embodiment gained lymphoid tuberculosis softening the hard mass preparation pill that eliminates the phlegm, every day three times, each 8.Take 10 days, all diseases disappear, and recover normal, recovery from illness.The recurrence of following up a case by regular visits to that so far there are no.
embodiment 5the lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, the primary raw material medicine of getting following weight is prepared from: Fructus Gleditsia veneer 10g, Herba Dendranthematis indici 11g, Radix Platycodonis 6g, Radix Salviae Miltiorrhizae 15g, Radix Scutellariae 8g, Rhizoma Cyperi 9.5g, Herba Erigerontis Annui 7g, Radix Polygoni Multiflori 9.5g, Dendrobium jenkinsii Wall ex Lindl． 25g, Spica Prunellae 19g, Fructus Forsythiae 9g, Manitis meat 10g, Radix Ranunculi Ternati 12g.
The eliminate the phlegm preparation method of preparation thick paste agent of lymphoid tuberculosis softening the hard mass:
(1) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, adds vinegar (consumption of vinegar be Manitis meat weight 1/5), fries 22 minutes with slow fire, and taking-up cools, and pulverization is crossed 180 mesh sieves, obtains fine powder;
(2) Radix Polygoni Multiflori, Radix Scutellariae are pulverized respectively rough, make solvent with the ethanol that mass concentration is 60% respectively, flood and carry out percolation after 26 hours, collect the liquid of filtering, reclaim ethanol, and evaporation and concentration to volume (by milliliter) is 2.3 times of crude drug in whole weight (by gram);
(3) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Rhizoma Cyperi, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are removed to impurity, after cleaning, put into terrine, (amount of water is to add 4.5 times of drug weight) adds water, first boil to boiling with big fire, after turn slow fire boiling 1.8 hours, leach medicinal liquid;
(4) step (2) gained concentrated solution and step (3) gained medicinal liquid are merged, then put into marmite and decoct 2.8 hours, obtain thick cream drug;
(5) get refined honey and join (amount of refined honey is 1.8 times of thick paste shape drug weight) in the thick cream drug of step (4) gained, then step (1) gained fine powder is added and mixed well, micro-refining, foam removal, seals and get final product in dress aseptic bottle.
test example 1the eliminate the phlegm clinical practice of preparation thick paste agent of embodiment 5 gained lymphoid tuberculosis softening the hard mass: in August, 2010-2012 year November, screen 272 routine lymphoid tuberculosis patients in 6 hospitals and carry out clinical observation.And be divided at random two groups, experimental group and matched group (every group of 136 people).Experimental group women 95 examples, male's 41 examples, age 25-62 year, 45.5 years old mean age, the course of disease 5 months-6 years.Matched group experimental group women 93 examples, male's 43 examples, age 24-61 year, 45.2 years old mean age, the course of disease 7 months-6.5 years.Between two groups of patients, the aspect such as sex, age, course of disease compares, and difference not statistically significant (P > 0.05), has comparability.Experimental group uses the present embodiment 5 products obtained therefroms, and matched group uses the scrofulous medicine of conventional therapy (as isoniazid, rifampicin, ethambutol and streptomycin etc.).Instructions of taking: every day three times, each 20 grams.Curative effect situation criterion: recovery from illness: lump disappears, crevasse healing, patient's no conscious sympton, 1 year recidivist not.Effective: lump dwindles more than 1/2, crevasse healing, symptom is obviously improved.Invalid: lump does not disappear, crevasse is not healed, and symptom is not improved.Always effectively comprise recovery from illness and effective.Result is as shown in table 1.
Table 1: take embodiment 5 product lymphoid tuberculosis patient treatment results
Using the eliminate the phlegm recovery from illness number of experimental group of preparation decoction of embodiment 5 gained lymphoid tuberculosis softening the hard mass is 102, and cure rate has reached 75%, and total effective rate has reached 97.79%, only has 3 people invalid, and the invalid number of matched group is up to 52, and total effective rate is only 61.76%.Experiment shows, use embodiment 5 gained lymphoid tuberculosis softening the hard mass eliminate the phlegm the agent of preparation thick paste compared with using other conventional medicines, its curative effect increases substantially, and cure rate significantly promotes, and inefficiency significantly reduces.
The present invention selects Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae etc. to carry out compatibility, makes after these drug regimens to produce synergism, can more effectively treat lymphoid tuberculosis.In side, Spica Prunellae relieves inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.Dendrobium jenkinsii Wall ex Lindl． nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.Fructus Gleditsia veneer detoxicating and resolving stagnation of pathogens, wind dispelling insecticide.Herba Dendranthematis indici, Radix Scutellariae, Herba Erigerontis Annui heat-clearing and toxic substances removing.Radix Platycodonis lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Rhizoma Cyperi promoting QI circulation for relieving depression.Radix Polygoni Multiflori removing toxic substances, disappears de-, loosening bowel to relieve constipation.Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Manitis meat nourishing YIN and clearing away heat, detoxicating and resolving stagnation of pathogens.Radix Ranunculi Ternati eliminating stagnation, detumescence.All medicines share, and melt nourishing YIN and clearing away heat, eliminate the phlegm, hard masses softening and resolving, and promoting QI circulation for relieving depression, how parasite killing detoxifies, plays altogether not the bursting of the core that disappears, the broken effect of scrofula, so lymphoid tuberculosis phase no matter all can treat, can obtain good efficacy.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although the present invention is had been described in detail with reference to previous embodiment, for a person skilled in the art, its technical scheme that still can record aforementioned each embodiment is modified, or part technical characterictic is wherein equal to replacement.Within the spirit and principles in the present invention all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. the lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm, is characterized in that, takes off the primary raw material medicine of stating weight proportion and is prepared from: Fructus Gleditsia veneer 5-12 part, Herba Dendranthematis indici 6-15 part, Radix Platycodonis 3-9 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Scutellariae 6-10 part, Rhizoma Cyperi 8-12 part, Herba Erigerontis Annui 6-9 part, Radix Polygoni Multiflori 6-15 part, Dendrobium jenkinsii Wall ex Lindl． 18-32 part, Spica Prunellae 15-25 part, Fructus Forsythiae 6-12 part, Manitis meat 8-16 part, Radix Ranunculi Ternati 8-16 part.
2. the lymphoid tuberculosis softening the hard mass according to claim 1 preparation that eliminates the phlegm, is characterized in that, takes off the primary raw material medicine of stating weight proportion and is prepared from: Fructus Gleditsia veneer 8-11 part, Herba Dendranthematis indici 9-12 part, Radix Platycodonis 4-7 part, Radix Salviae Miltiorrhizae 14-17 part, Radix Scutellariae 7.5-9 part, Rhizoma Cyperi 9-11 part, Herba Erigerontis Annui 6.5-8 part, Radix Polygoni Multiflori 8-11 part, Dendrobium jenkinsii Wall ex Lindl． 23-27 part, Spica Prunellae 17-22 part, Fructus Forsythiae 7-10 part, Manitis meat 9-12 part, Radix Ranunculi Ternati 10-14 part.
3. the lymphoid tuberculosis softening the hard mass according to claim 1 preparation that eliminates the phlegm, is characterized in that, takes off the primary raw material medicine of stating weight proportion and is prepared from: 10 parts of Fructus Gleditsia veneer, 11 parts, Herba Dendranthematis indici, 6 parts of Radix Platycodoniss, 15 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Scutellariaes, 9.5 parts of Rhizoma Cyperis, 7 parts of Herba Erigerontis Annuis, 9.5 parts of Radix Polygoni Multiflori, 25 parts of Dendrobium jenkinsii Wall ex Lindl．, 19 parts of Spica Prunellaes, 9 parts of Fructus Forsythiaes, 10 parts of Manitis meat, 12 parts of Radix Ranunculi Ternatis.
4. according to the arbitrary described lymphoid tuberculosis softening the hard mass of the claim 1-3 preparation that eliminates the phlegm, it is characterized in that, this lymphoid tuberculosis softening the hard mass preparation that eliminates the phlegm is made to pharmaceutically acceptable decoction, powder, pill and thick paste agent.
5. the lymphoid tuberculosis softening the hard mass according to claim 4 preparation that eliminates the phlegm, is characterized in that, the preparation method of described decoction is:
(1) Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are removed to impurity, after cleaning, put into terrine, soak 2.5-5 hour (preferably soaking 3.2 hours), amount of water is doubly (preferably 4.2 times) of 3-6.5 that add drug weight;
(2) first boil to boiling with big fire, after turn slow fire boiling 0.8-3 hour (preferably 2 hours), leach medicinal liquid;
(3) (talcous weight is 2-5 times of acacia wood tare weight amount to get Pulvis Talci; Preferably, talcous weight is 3 times of acacia wood tare weight amount), put in pot, make popular with moderate heat, add Fructus Gleditsia veneer, stir 0.5-2 hour (preferably 1.5 hours), take out, sieve removes Pulvis Talci, cool, pulverization, crosses 150-230 mesh sieve (preferred mistake 200 mesh sieves);
(4) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, and (consumption of vinegar is the 1/16-1/5 of Manitis meat weight to add vinegar; Preferably, the consumption of vinegar be Manitis meat weight 1/6), with slow fire fry 12-28 minute (preferably 18 minutes), taking-up cools, pulverization, cross 160-230 mesh sieve (preferred mistake 200 mesh sieves), obtain fine powder;
(5) step (3) and step (4) gained fine powder are joined in step (2) gained medicinal liquid, to obtain final product.
6. the lymphoid tuberculosis softening the hard mass according to claim 4 preparation that eliminates the phlegm, is characterized in that, the preparation method of described powder is:
(1) Manitis meat is cleaned, put into boiling water pot and scald, pull clean shredding out, dry in the shade, by the Manitis meat pulverization drying in the shade, cross 180-230 mesh sieve (preferred mistake 210 mesh sieves), obtain fine powder;
(2) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are pulverized respectively, cross 170-250 mesh sieve (preferred mistake 210 mesh sieves), obtain fine powder;
(3) by step (1) and step (2) gained fine powder mix homogeneously, obturage with paper wrapper, in 105-120 DEG C (preferably 110 DEG C) dry heat sterilization 3-4 hour (preferably 3.5 hours), be sealed in plastic bag, 5 grams every bag, to obtain final product.
7. the lymphoid tuberculosis softening the hard mass according to claim 4 preparation that eliminates the phlegm, is characterized in that, the preparation method of described pill is:
(1) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, and (consumption of vinegar is the 1/14-1/2 of Manitis meat weight to add vinegar; Preferably, the consumption of vinegar be Manitis meat weight 1/4), with slow fire fry 18-40 minute (preferably 25 minutes), taking-up cools, pulverization, cross 150-180 mesh sieve (preferably 160 mesh sieves), obtain fine powder;
(2) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Radix Scutellariae, Rhizoma Cyperi, Herba Erigerontis Annui, Radix Polygoni Multiflori, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are pulverized respectively, cross 140-200 mesh sieve (preferred mistake 160 mesh sieves), obtain fine powder;
(3), by step (1) and step (2) gained fine powder mix homogeneously, taking water as wetting agent, making diameter is that the preferred diameter of 2-6mm(is 3mm) little pill, be drying to obtain.
8. the lymphoid tuberculosis softening the hard mass according to claim 4 preparation that eliminates the phlegm, is characterized in that, the preparation method of described thick paste agent is:
(1) Manitis meat is cleaned, dice, dries in the shade, and the Manitis meat drying in the shade is placed in pot, adds vinegar, fries 15-40 minute (preferably 22 minutes) with slow fire, and taking-up cools, and pulverization is crossed 170-200 mesh sieve (preferably 180 mesh sieves), obtains fine powder;
(2) Radix Polygoni Multiflori, Radix Scutellariae are pulverized respectively rough, the ethanol that is 50%-70% by mass concentration respectively (ethanol that preferred mass concentration is 60%) is made solvent, flood and after (preferably flooding 26 hours), carry out percolation in 20-30 hour, the collection liquid of filtering, reclaim ethanol, and evaporation and concentration to volume (by milliliter) be doubly (preferred evaporation and concentration to volume is 2.3 times of crude drug in whole weight) of 2.2-2.6 of crude drug in whole weight (by gram);
(3) Fructus Gleditsia veneer, Herba Dendranthematis indici, Radix Platycodonis, Radix Salviae Miltiorrhizae, Rhizoma Cyperi, Herba Erigerontis Annui, Dendrobium jenkinsii Wall ex Lindl．, Spica Prunellae, Fructus Forsythiae, Radix Ranunculi Ternati are removed to impurity, after cleaning, put into terrine, add water, first boil to boiling with big fire, after turn slow fire boiling 0.8-3 hour (preferably 1.8 hours), leach medicinal liquid;
(4) step (2) gained concentrated solution and step (3) gained medicinal liquid are merged, then put into marmite and decoct 1.5-4 hour (preferably decocting 2.8 hours), obtain thick cream drug;
(5) get sugar refinery or refined honey join in the thick cream drug of step (4) gained (amount of sugar refinery or refined honey be thick paste shape drug weight 1.5-3.5 doubly; Preferably, the amount of sugar refinery or refined honey is 1.8 times of thick paste shape drug weight), then step (1) gained fine powder is added and mixed well, micro-refining, foam removal, seals and get final product in dress aseptic bottle.
9. the lymphoid tuberculosis softening the hard mass according to claim 8 preparation method of preparation thick paste agent of eliminating the phlegm, is characterized in that, the amount that adds vinegar be the 1/10-1/4(of Manitis meat weight preferably add the amount of vinegar be Manitis meat weight 1/5).
10. the lymphoid tuberculosis softening the hard mass according to claim 8 preparation method of preparation thick paste agent of eliminating the phlegm, is characterized in that, amount of water is doubly (preferably amount of water is to add 4.5 times of drug weight) of 3.6-5.8 that adds drug weight.
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| CN104784388A (en) * | 2015-05-13 | 2015-07-22 | 范道锋 | Traditional Chinese medicine externally applied patch for treating lymphnoditis and preparation method thereof |
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| CN102380038A (en) * | 2010-08-25 | 2012-03-21 | 蔡英杰 | Medicine for treating scrofula and red-hot needle therapy |
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