CN105616558A - Heat-clearing and diuresis-promoting ointment for acute bacterial dysentery - Google Patents
Heat-clearing and diuresis-promoting ointment for acute bacterial dysentery Download PDFInfo
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- CN105616558A CN105616558A CN201610095593.3A CN201610095593A CN105616558A CN 105616558 A CN105616558 A CN 105616558A CN 201610095593 A CN201610095593 A CN 201610095593A CN 105616558 A CN105616558 A CN 105616558A
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Abstract
The invention discloses a heat-clearing and diuresis-promoting ointment for acute bacterial dysentery.The ointment is mainly prepared from, by weight, 18-40 parts of herba portulacae, 6-9 parts of cochinchina momordica seeds, 10-20 parts of radix pulsatillae, 5-15 parts of radix aucklandiae, 15-25 parts of capitate knotweed herb, 6-12 parts of herb of twinleaf zornia, 3-10 parts of largeleaf dogwood bark, 5-12 parts of China mahonia roots and 15-25 parts of honeysuckle flowers.The traditional Chinese medicine composition is scientific in formula, the preparation method is simple, use is convenient, and the effects of clearing heat, promoting diuresis, removing toxicity and cooling the blood on the acute bacterial dysentery are achieved.
Description
Divisional application, original applying number 2014105827025, applying date 2014.10.28, title acute bacillary dysentery QiReLiShi herbs compositions and preparation method.
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of acute bacillary dysentery QiReLiShi herbs compositions and preparation method.
Background technology
Bacillary dysentery is children's's a kind of infectious intestinal disease more typically, caused by dysentery bacterium. Clinically with heating, stomachache, diarrhoea, tenesmus and arrange the loose stool of mucous, pus and blood for its cardinal symptom. Clinically course of disease person within 2 months is called acute bacillary dysentery, point 3 types, namely plain edition, light-duty and toxic type. Plain edition shows as heating of feeling cold, stomachache, diarrhoea, accompanies tenesmus. Stomachache, based on left lower quadrant, in paroxysmal, alleviates greatly after an action of the bowels. Stool every day tens times to tens times, typical case person is that mucus bloody purulent stool is with tenesmus sense. Toxic type acute bacillary dysentery onset is hurried, and change rapidly, can behave as high heat, headache, vomiting, irritated, drowsiness, even blood pressure drops, consciousness changing. Treatment acute bacillary dysentery is usually by having Western medicine at present, and the antidiarrheal effect of Western medicine is fast but stomach, liver can be caused injury in various degree, and side effect is bigger.
Publication No. CN103417671A(application number 201210175550.8) Chinese patent literature disclose a kind of Chinese medicine treating acute bacillary dysentery, it is made up of the component of following weight portion: Semen Plantaginis 40-50 gram, Radix Sophorae Flavescentis 20-40 gram, Fructus Crataegi (parched to brown) 15-25 gram, grinds to the powder altogether. Publication No. CN102772598A(application number 201210295050.8) Chinese patent literature disclose a kind of Chinese medicine treating bacillary dysentery. The Chinese medicine of this treatment bacillary dysentery is with Rhizoma Acori Graminei, Spica Prunellae, Folium Isatidis, the Radix Aucklandiae, Fructus Crataegi, storage, Flos Narcissi chinensis, Flos Sophorae, Herba Portulacae, Flos Hibisci, Herba Agrimoniae, Cortex Pini Massonianae, Herba Salviae Chinensis, flower of poplar, Radix Sanguisorbae and Flos Musae for raw material, formulated according to certain weight proportion. Publication No. CN103417590A(application number 201210182815.7) Chinese patent literature disclose a kind of Chinese medicine treating chronic bacillary dysentery, it is characterized in that it is made up of the component of following weight portion: Pericarpium Granati 50 grams, Radix Angelicae Sinensis 15 grams uses clear water decoction, and once clothes go down.
Now for the treatment of dysentery mainly based on doctor trained in Western medicine, quickly but side effect is very big for therapeutic effect, and liver is easily generated injury, and Chinese traditional treatment of comparing is more suitable for, but because traditional Chinese medical science theory is different, effect difference is relatively big, so also needing to further research.
Summary of the invention
For problem of the prior art, it is an object of the invention to provide the Chinese medicine composition of the treatment acute bacillary dysentery that a kind of effect is notable, take safety has no side effect.
The technical scheme is that
Acute bacillary dysentery QiReLiShi herbs compositions, is mainly prepared from by following bulk drugs, is weight portion: Herba Portulacae 18-40; Semen Momordicae 6-9; Radix Pulsatillae 10-20; Radix Aucklandiae 5-15; Herba Polygoni Capitati 15-25; Herba Zornia Diphyllae 6-12; Cortex Corni macrophyllae 3-10; Graperoot 5-12; Flos Lonicerae 15-25.
Preferred scheme is: Herba Portulacae 20-38; Semen Momordicae 7-8; Radix Pulsatillae 12-18; Radix Aucklandiae 8-12; Herba Polygoni Capitati 18-22; Herba Zornia Diphyllae 8-10; Cortex Corni macrophyllae 5-8; Graperoot 7-10; Flos Lonicerae 18-22.
More preferably: Herba Portulacae 29, Semen Momordicae 7.5, the Radix Pulsatillae 15, the Radix Aucklandiae 10, Herba Polygoni Capitati 20, Herba Zornia Diphyllae 9, Cortex Corni macrophyllae 6.5, graperoot 8.5, Flos Lonicerae 20.
Present invention also offers and this Chinese medicine composition is made pharmaceutically acceptable decoction, thick paste agent, pill and granule.
The preparation method of described decoction is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 40-60 mesh sieve (preferably 50 order), be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) taking Cortex Corni macrophyllae addition rice vinegar to mix thoroughly, vexed moisture-inhibiting is moistened, and the time is 15-20 minute (being preferably 18 minutes), after vinegar is sucked, puts into container, slow fire heating fried dry, and taking-up is dried in the air cool standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 1-3 hour (preferably 2 hours), after intense fire is boiled, add step (1) (2) gains and the Herba Polygoni Capitati cleaned, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire and decoct 40-60 minute (preferably 50 minutes), filter;
(4) recrement boiling again, filters, merges with step (3) gained filtrate and be concentrated into 1/2nd of original volume, and sterilizing encapsulation obtains Chinese medicine composition decoction.
The preparation method of described decoction, 6-8 times (preferably 7 times) that amount is medical material weight that step (3) adds water.
The preparation method of described thick paste is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 40-60 mesh sieve (preferably 50 order), be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) taking Cortex Corni macrophyllae addition rice vinegar to mix thoroughly, vexed moistening, the time is 15-20 minute (preferably 18 minutes), after vinegar is sucked, puts into container, slow fire heating fried dry, and taking-up is dried in the air cool standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 1-3 hour (preferably 2 hours), after intense fire is boiled, add step (1) (2) gains and the Herba Polygoni Capitati cleaned, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire to decoct 50 minutes, filter;
(4) recrement boiling again, the persistent period is 30 minutes, filters and merges with step (3) gained filtrate, is concentrated into relative density 1.20-1.30(60 DEG C) thick paste of (preferably 1.25), sterilizing, obtain thick paste agent.
The preparation method of described pill is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 70-90 mesh sieve (preferably 80 order), be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) take Cortex Corni macrophyllae add rice vinegar mix thoroughly, vexed moistening, the time is 15-20 minute (preferably 18 minutes), after vinegar is sucked, puts into container, slow fire heating fried dry, take out dry in the air cool grind to form end standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 1-3 hour (preferably 2 hours), after intense fire is boiled, add clean Herba Polygoni Capitati, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire decoct 50 minutes, filter;
(4) by step (1), (2), (3) gained medicated powder and filtrate mix homogeneously, adding refined honey according to the ratio of 4:1, make and have plastic ball bar, sterilizing segmentation is packaged to be the pill of 0.5g/.
The preparation method of described granule is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 70-90 mesh sieve (preferably 80 order), be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) take Cortex Corni macrophyllae add rice vinegar mix thoroughly, vexed moistening, the time is 15-20 minute (preferably 18 minutes), after vinegar is sucked, puts into container, slow fire heating fried dry, take out dry in the air cool grind to form end standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 1-3 hour (preferably 2 hours), after intense fire is boiled, add clean Herba Polygoni Capitati, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire decoct 50 minutes, filter;
(4) recrement boiling again, filter, it is combined and concentrated to relative density 1.18-1.21(60 DEG C with step (3) gained filtrate) thick paste of (preferably Ei 1.20), add step (1) (2) gained medicated powder, mix homogeneously, make the soft material that light pressure then dissipates, be pressed through 14-18 mesh sieve, dry at 70 DEG C and obtain Chinese medicine granules.
Present invention also offers the application when the medicine of preparation treatment acute bacillary dysentery of the described Chinese medicine composition.
The pharmacology of the present invention main raw material of Chinese medicine used is as follows:
Herba Portulacae: nature and flavor with return through acid, cold. Return liver, large intestine channel. Function with cure mainly: heat-clearing and toxic substances removing, cooling blood for hemostasis, dysentery relieving. For toxic-heat and blood stasis, carbuncle furuncle, eczema, erysipelas, snake bite and insect sting, have blood in stool, hemorrhoidal bleeding, metrostaxis.
Semen Momordicae: base: for the seed of Cucurbitaceae Momordica plant wood nose. Composition: seed containing saponin: fixed I and I c of Semen Momordicae saponin �� and II Semen Momordicae, albumen and peptides: Semen Momordicae glycoprotein S, N-powder stamen Buxus sinica (Rehd.et Wils.) alcohol pentapeptide, momordic acid you, oleanolic acid, sterol, Cochinchinin etc. The property of medicine: bitter, micro-sweet, temperature, poisonous. Return liver, spleen, stomach warp. Function cures mainly: dispersing swelling and dissipating binds, chases after wind pain relieving. Cure mainly carbuncle, furuncle, innominate toxic swelling, hemorrhoid, acne, black dry black once, mastitis, tuberculous lymphadenitis, dysentery, rheumatic arthralgia, muscle arteries and veins contracture, gingival swelling and pain.
The Radix Pulsatillae: nature and flavor with return through: bitter, cold. Return stomach, large intestine channel. Function with cure mainly: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery. For toxic-heat and blood stasis, pudendal pruritus leukorrhagia.
The Radix Aucklandiae: nature and flavor with return through: pungent, bitter, temperature. Return spleen, stomach, large intestine, three burnt, gallbladder meridians. Function with cure mainly: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion. For the breast side of body, abdominal distention, weight after dysentery, food stagnation does not disappear, anorexia. Radix Aucklandiae (roasted) reality intestinal antidiarrheal. For stomachache of having loose bowels.
Herba Polygoni Capitati: base: for the herb of polygonaceae plant Herba Polygoni Capitati. Chemical analysis: Herba Polygoni Capitati herb is containing benzaldehyde, acetic acid, 24-hydroxyl lignocerane-3-ketone, 29-hydroxyl nonacosane-3-ketone, cupreol, gallic acid. Nature and flavor: bitter; Pungent; Cool in nature. Function cures mainly: clearing away heat-damp and promoting diuresis; Promoting blood circulation and stopping pain. Main dysentery; Pyelonephritis; Cystitis; Lithangiuria; Rheumatalgia; Traumatic injury; Mumps; Skin infection; Eczema.
Herba Zornia Diphyllae: base: for the herb of pulse family Herba Zornia Diphyllae platymiscium Herba Zornia Diphyllae. Composition: herb is containing coumarin. The property of medicine: bitter, sweet, cool. Function cures mainly: heat-clearing and toxic substances removing, cool the blood dissipate blood stasis, and dehumidify diuresis. Curing mainly anemopyretic cold, pharyngalgia, skin infection swells and ache, venom, and jaundice is had loose bowels, dysentery, infantile malnutrition.
Cortex Corni macrophyllae: base; Bark is obtained for Cornaceae fogfruit Lignum corni macrophyllae. The property of medicine: bitter, flat. Function cures mainly: dispelling wind and removing obstruction in the collateral, dampness removing antidiarrheal. Curing mainly bones and muscles pain, quadriplegia, dysentery, watery diarrhea is suffered from abdominal pain.
Graperoot: base: for the root of Berberidaceae Mahonia fortunei (Lindl.) Fedde platymiscium Mahonia bealei (Fort.) Carr., mahonia fortuneiFedde. Composition: 1. Mahonia bealei (Fort.) Carr. root is containing alkaloid: berberine. 2. south China graperoot is containing alkaloid: isotetrandrine, berberine, palmatine, jateorhizine and berbamine. The property of medicine: " Traditional Chinese Medicine in Sichuan will " nineteen sixty version: " cold in nature, bitter in the mouth. " function cures mainly: heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling. Cure mainly hygropyretic dysentery, diarrhoea, jaundice, pulmonary tuberculosis hemoptysis, throat pain, toothache, conjunctival congestion and swelling pain, traumatic injury, skin infection, eczema, scald etc. Compatibility and incompatibility of drugs: the careful clothes of Deficiency and coldness of spleen and stomach person.
Flos Lonicerae: sweet in the mouth, micro-hardship, cold nature. Having heat-clearing and toxic substances removing, expelling pathogenic factors from the exterior is gone out, effect of stomach function regulating preventing or arresting vomiting, stops up resistance, disorder of stomach-QI, fever and irritability for pathogenic heat.
Acute bacillary dysentery QiReLiShi herbs composite formula science provided by the invention, preparation method is simple, easy to use. In addition, its excellent part is also manifested by:
1, the present invention is directed to acute bacillary dysentery, have effect of clearing away heat-damp and promoting diuresis, removing toxic substances removing heat from blood;
2, selected medical material in the present invention, cheap, does not increase the financial burden of patient;
3, each dosage form meets theory of Chinese medical science, can play the curative effect of medicine to greatest extent.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Embodiment 1 acute bacillary dysentery QiReLiShi herbs compositions, is mainly prepared from by following bulk drugs: Herba Portulacae 18g, Semen Momordicae 6g, Radix Pulsatillae 10g, Radix Aucklandiae 5g, Herba Polygoni Capitati 15g, Herba Zornia Diphyllae 6g, Cortex Corni macrophyllae 3g, graperoot 5g, Flos Lonicerae 15g. The preparation method of above-mentioned Chinese medicine composition decoction is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 40 mesh sieves, be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) taking Cortex Corni macrophyllae addition rice vinegar to mix thoroughly, vexed moisture-inhibiting is moistened, and the time is 15 minutes, after vinegar is sucked, puts into container, slow fire heating fried dry, and taking-up is dried in the air cool standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 1 hour, the water yield is 6 times of medical material weight, after intense fire is boiled, add step (1) (2) gains and the Herba Polygoni Capitati cleaned, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire to decoct 40 minutes, filter;
(4) recrement boiling again, filters, merges with step (3) gained filtrate and be concentrated into 1/2nd of original volume, and sterilizing encapsulation obtains Chinese medicine composition decoction.
Embodiment 2 acute bacillary dysentery QiReLiShi herbs compositions, is mainly prepared from by following bulk drugs: Herba Portulacae 40g, Semen Momordicae 9g, Radix Pulsatillae 20g, Radix Aucklandiae 15g, Herba Polygoni Capitati 25g, Herba Zornia Diphyllae 12g, Cortex Corni macrophyllae 10g, graperoot 12g, Flos Lonicerae 25g. The manufacture method of above-mentioned Chinese medicine composition thick paste agent is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 50 mesh sieves, be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) taking Cortex Corni macrophyllae addition rice vinegar to mix thoroughly, vexed moistening, the time is 18 minutes, after vinegar is sucked, puts into container, slow fire heating fried dry, and taking-up is dried in the air cool standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 2 hours, after intense fire is boiled, add step (1) (2) gains and the Herba Polygoni Capitati cleaned, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire to decoct 50 minutes, filter;
(4) recrement boiling again, the persistent period is 30 minutes, filter merge with step (3) gained filtrate, be concentrated into relative density 1.25(60 DEG C) thick paste, sterilizing, obtain thick paste agent.
Instructions of taking: twice daily, once two soup ladles, warm boiled water, five days is a course for the treatment of.
Model case: xxx, male, 31 years old. Main suit: heating, dizzy, stomachache two days, with bloody purulent stool; History of present illness: suddenly heating of returning after patient's tourism, fear cold, without shiver with cold, hypogastric region rest pain and diarrhoea, a small amount of bloody purulent stool, absence of nausea and vomiting symptom again simultaneously. Diagnosis is: acute bacillary dysentery.
Taking the gained traditional Chinese medicine thick paste agent of this example, after three days, patient's phenomenon of suffering from diarrhoea substantially is alleviated, continue to take two the course for the treatment of order, patient's discomfort disease disappears, and physical recovery is healthy, and self-induction is fully recovered.
Embodiment 3 acute bacillary dysentery QiReLiShi herbs compositions, is mainly prepared from by following bulk drugs: Herba Portulacae 20g, Semen Momordicae 7g, Radix Pulsatillae 12g, Radix Aucklandiae 8g, Herba Polygoni Capitati 18g, Herba Zornia Diphyllae 8g, Cortex Corni macrophyllae 5g, graperoot 7g, Flos Lonicerae 18g. The manufacture method of above-mentioned Chinese medicine composition pill is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 80 mesh sieves, be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) take Cortex Corni macrophyllae add rice vinegar mix thoroughly, vexed moistening, the time is 18 minutes, after vinegar is sucked, puts into container, slow fire heating fried dry, take out dry in the air cool grind to form end standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 2 hours, after intense fire is boiled, add clean Herba Polygoni Capitati, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire decoct 50 minutes, filter;
(4) by step (1), (2), (3) gained medicated powder and filtrate mix homogeneously, adding refined honey according to the ratio of 4:1, make and have plastic ball bar, sterilizing segmentation is packaged to be the pill of 0.5g/.
Instructions of taking: every day, sooner or later respectively once once two ball, five days was a course for the treatment of.
Model case: xxx, women, 5 years old. Medical history: because eating unclean fruit by mistake, heating, nausea and vomiting symptom abdominal pain diarrhea, stool containing pus and blood occur, is acute bacillary dysentery through hospital diagnosis. Taking this example gained medicine pill, patient suffers from diarrhoea in three days and stops, and pain phenomenon alleviates, and other uncomfortable diseases alleviate, and continue to strengthen a course for the treatment of, and health is got well substantially, goes each physical and chemical index of examination in hospital all qualified.
Embodiment 4 acute bacillary dysentery QiReLiShi herbs compositions, is mainly prepared from by following bulk drugs: Herba Portulacae 38g, Semen Momordicae 8g, Radix Pulsatillae 18g, Radix Aucklandiae 12g, Herba Polygoni Capitati 22g, Herba Zornia Diphyllae 10g, Cortex Corni macrophyllae 8g, graperoot 10g, Flos Lonicerae 22g. The manufacture method of above-mentioned Chinese medicinal composition granules is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 80 mesh sieves, be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) take Cortex Corni macrophyllae add rice vinegar mix thoroughly, vexed moistening, the time is 18 minutes, after vinegar is sucked, puts into container, slow fire heating fried dry, take out dry in the air cool grind to form end standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 2 hours, after intense fire is boiled, add clean Herba Polygoni Capitati, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire decoct 50 minutes, filter;
(4) recrement boiling again, filter, be combined and concentrated to relative density 1.20(60 DEG C with step (3) gained filtrate) thick paste, add step (1) (2) gained medicated powder, mix homogeneously, make the soft material that light pressure then dissipates, be pressed through 14-18 mesh sieve, dry at 70 DEG C and obtain Chinese medicine granules.
Instructions of taking: every day, sooner or later respectively once once a bag, warm boiled water, five days was a course for the treatment of.
Model case: xxx, women, 58 years old. Medical history: patient generated heat suddenly before two days diarrhoea, and about 20 minutes once, and a small amount of pus and blood in just, vomiting phenomenon, lassitude, limbs fatigue once occurred in period, was toxic type bacillary dysentery through hospital diagnosis. Taking this example gained Chinese medicine granules, after two courses for the treatment of, patient defecates normally, and malaise symptoms eliminates, and self-induction is fully recovered.
Embodiment 5 acute bacillary dysentery QiReLiShi herbs compositions, is mainly prepared from by following bulk drugs: Herba Portulacae 29g, Semen Momordicae 7.5g, Radix Pulsatillae 15g, Radix Aucklandiae 10g, Herba Polygoni Capitati 20g, Herba Zornia Diphyllae 9g, Cortex Corni macrophyllae 6.5g, graperoot 8.5g, Flos Lonicerae 20g. The manufacture method of above-mentioned Chinese medicine composition decoction is:
(1) Semen Momordicae being removed impurity, be ground into powder, cross 50 mesh sieves, be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) taking Cortex Corni macrophyllae addition rice vinegar to mix thoroughly, vexed moisture-inhibiting is moistened, and the time is 18 minutes, after vinegar is sucked, puts into container, slow fire heating fried dry, and taking-up is dried in the air cool standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 2 hours, the water yield is 7 times of medical material weight, after intense fire is boiled, add step (1) (2) gains and the Herba Polygoni Capitati cleaned, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire to decoct 50 minutes, filter;
(4) recrement boiling again, filters, merges with step (3) gained filtrate and be concentrated into 1/2nd of original volume, and sterilizing encapsulation obtains Chinese medicine composition decoction.
Instructions of taking: every day, sooner or later respectively once a 150-200ml, five days was a course for the treatment of.
The clinical practice of test example 1 embodiment 5 gained Chinese medicine composition decoction: foundation hospital outpatient case history, screening acute bacillary dysentery patient 389 example, wherein women 217 example, male 172 example, oldest 70 years old, minimum 5 years old, 35.6 years old mean age. Before test, this crowd is carried out Continuous Observation, record symptom and change, is randomly divided into two groups, experimental group (N=254); Matched group (N=135).
Experimental group takes embodiment 5 products obtained therefrom, and sooner or later respectively once, each 150-200ml, five days is a course for the treatment of; Matched group uses other conventional method (norfloxacin, bactrim, gentamycin or transfusion).
Curative effect determinate standard: cure: malaise symptoms eliminates, and physical and chemical index is normal; Effective: cardinal symptom substantially eliminates, main physical and chemical index makes moderate progress; Invalid: main physical and chemical index is front with treatment unchanged. Total effective rate=cure rate+effective percentage.
Clinical effectiveness: after taking two courses for the treatment of, experimental group: cure rate 81.1%(206/254), effective percentage 16.9%(43/254) and, inefficiency 2%(5/254); Matched group: cure rate 60%(81/135), effective percentage 24.4%(33/135), inefficiency 15.6%(21/135)
By observing the rehabilitation situation of two groups of acute bacillary dysentery patients, it has been found that embodiment 5 products obtained therefrom is better than conventional products, and advantage shows that administration time is short, cure rate is high. The total effective rate of experimental group is 98%, hence it is evident that be better than the 84.4% of matched group.
The present invention with heat-clearing and toxic substances removing, regulate the flow of vital energy and blood is for the rule for the treatment of, multiple medical material synergistic combination, treats acute bacillary dysentery targetedly, then the effect such as the dampness removing antidiarrheal adding the circulation of qi promoting spleen invigorating of other accessory drugss such as Radix Aucklandiae, Cortex Corni macrophyllae, effect is notable, and its total effective rate of clinical trial certificate can reach 98%.
It should be pointed out that, the detailed description of the invention more representational example that is the present invention, it is clear that technical scheme is not limited to above-described embodiment, it is also possible to have many variations. Those of ordinary skill in the art, with the present invention undoubted the obtaining of clearly disclosed or according to file written description, be all considered as this patent scope of the claimed.
Claims (2)
1. acute bacillary dysentery QiReLiShi herbs compositions, it is characterised in that be mainly prepared from by following bulk drugs, be weight portion: Herba Portulacae 40; Semen Momordicae 9; The Radix Pulsatillae 20; The Radix Aucklandiae 15; Herba Polygoni Capitati 25; Herba Zornia Diphyllae 12; Cortex Corni macrophyllae 10; Graperoot 12; Flos Lonicerae 25.
2. the preparation method of acute bacillary dysentery QiReLiShi herbs compositions thick paste according to claim 1, it is characterised in that
(1) Semen Momordicae being removed impurity, be ground into powder, cross 40-60 mesh sieve (preferably 50 order), be then placed in pot, the dry stir-fry of little fire, to there being fragrance to blow out, is taken out standby;
(2) taking Cortex Corni macrophyllae addition rice vinegar to mix thoroughly, vexed moistening, the time is 15-20 minute (preferably 18 minutes), after vinegar is sucked, puts into container, slow fire heating fried dry, and taking-up is dried in the air cool standby;
(3) Herba Portulacae, the Radix Pulsatillae, the Radix Aucklandiae, graperoot rinse shave are placed in marmite, and add water retting 1-3 hour (preferably 2 hours), after intense fire is boiled, add step (1) (2) gains and the Herba Polygoni Capitati cleaned, Herba Zornia Diphyllae, Flos Lonicerae, turn little fire to decoct 50 minutes, filter;
(4) recrement boiling again, the persistent period is 30 minutes, filters and merges with step (3) gained filtrate, is concentrated into relative density 1.20-1.30(60 DEG C) thick paste of (preferably 1.25), sterilizing, obtain thick paste agent.
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CN201610095594.8A Withdrawn CN105616559A (en) | 2014-10-28 | 2014-10-28 | Composition for treating acute bacillary dysentery |
CN201610095591.4A Withdrawn CN105560410A (en) | 2014-10-28 | 2014-10-28 | Granules for treating acute bacillary dysentery |
CN201610095593.3A Withdrawn CN105616558A (en) | 2014-10-28 | 2014-10-28 | Heat-clearing and diuresis-promoting ointment for acute bacterial dysentery |
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