CN104971157A - Externally applied powder for treating beriberi and preparation method - Google Patents
Externally applied powder for treating beriberi and preparation method Download PDFInfo
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Abstract
The invention discloses externally applied powder for treating beriberi. The powder is prepared from the following main active pharmaceutical ingredients in parts by weight: 10-16 parts of perilla stem, 8-13 parts of pummelo peel, 11-17 parts of garden balsam stem, 7-12 parts of tangerine leaf, 9-15 parts of sarmentose pepper herb, 10-15 parts of lobed actinostemma herb, 8-16 parts of pyrolusite, 7-13 parts of herba schizonepetae, 9-16 parts of Taiwan beautyberry leaf, 8-15 parts of root of slenderpediecl meadowrue, 6-12 parts of Jenkine dendrobium, 11-16 parts of twig and leaf of orangeeye butterflybush, 8-14 parts of root-bark of Chinese hydrangeavine and 10-17 parts of all-grass of Japanese knotweed. Through summary of the clinical practice for many years, the powder has the functions of sterilization and detoxication and the functions of removing dampness and relieving itching and has obvious curative effects.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of the outer of beriberi for the treatment of and powder and method for making.
Background technology
Beriberi is being commonly called as of tinea pedis, is the dermatosis that fungal infection causes, has infectiousness.In China, the sickness rate of tinea pedis is also quite high.Do not have sebaceous gland between the vola of people and toe, thus lack the fatty acid suppressing skin filamentous fungi, physiological defense function is poor, and the sweat gland of skin at these positions is very abundant, perspire many, poor, the locally damp warm of air circulation, is conducive to the growth of filamentous fungi in addition.In addition, vola area skin horny layer is thicker, and the keratin in horny layer is the abundant nutrition material of fungus, is conducive to the growth of fungus.Its skin lesion is first one-sided (i.e. single foot) generation often, just infects to offside after several weeks or several months.Vesicle mainly appears at toe abdomen and toe side, and be most commonly between three or four toes, vola also can occur, for dark in property phlysis, can be fused into bulla gradually.The skin lesion of tinea pedis has a feature, i.e. clear border, can gradually to external expansion.Because of PD or scratch, erosion, sepage can be there is, even bacteriological infection, occur pustule etc.
Publication No. CN 104474368 A(application number 201410699907.1) Chinese patent literature disclose a kind of medicine for the treatment of beriberi, by Radix Scutellariae, Radix Arnebiae (Radix Lithospermi), Fructus Forsythiae, Semen Coicis, Flos Lonicerae, Flos Gardeniae, Radix Angelicae Sinensis, dried Alumen, Calomelas, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Coptidis, Radix Sophorae Flavescentis, Herba Houttuyniae, the kinds of traditional Chinese medicines such as Adeps sus domestica are made, adopt foot bath hold concurrently coating mode use.Publication No. CN 104644836 A(application number 201310602890.9) Chinese patent literature disclose a kind of athlete foot powder being used for the treatment of beriberi, be made up of following weight parts raw material: Radix Sophorae Flavescentis 20 ~ 30; Cortex Dictamni 20 ~ 30; Herba Portulacae 15 ~ 20; Herba Plantaginis 15 ~ 20; Cortex Phellodendri 10 ~ 15; Rhizoma Atractylodis 10 ~ 15; Spice 0.01 ~ 0.02.Publication No. CN 104667115A(application number 201310624877.3) Chinese patent literature disclose a kind of Chinese medicinal foot bath powder for the treatment of beriberi, it comprises following Chinese crude drug composition: Herba pteridis vittatae 3-5 part, Cortex Phellodendri 3-8 part, Rhizoma Fagopyri Dibotryis 10-15 part, Fructus Amomi Rotundus 1-3 part, Flos Chrysanthemi Indici 5-7 part, Radix Angelicae Sinensis 5-8 part, Radix Angelicae Dahuricae 5-8 part, Herba Lycopodii 5-10 part.
The medicament categories being used for the treatment of beriberi at present is on the market various, and therapeutic effect is very different, and some drugs can only play the effect of alleviation mostly, can not treat at all, therefore needs to develop a kind of instant effect, recoverable Chinese medicine formula.
Summary of the invention
For the problem of prior art, the outer for the treatment of beriberi that the object of this invention is to provide a kind of Be very effective, the use safety suitability wide is powdered and method for making.
Technical scheme of the present invention is:
A kind of the outer of beriberi for the treatment of is powdered, and is prepared from, is mass parts: Caulis Perillae 10-16 primarily of following bulk drugs; Exocarpium Citri Grandis 8-13; Herba speranskiae tuberculatae 11-17; Folium Citri tangerinae 7-12; Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 9-15; Lobed Actinostemma Herb 10-15; Pyrolusitum 8-16; Herba Schizonepetae 7-13; Folium Callicarpae Formosanae 9-16; Radix Thalictri Trichopi 8-15; Dendrobium jenkinsii Wall ex Lindl． 6-12; Ramulus et folium buddlejae davidii 11-16; Cortex schizophragmatis integrifolii radicis 8-14; Herba Polygoni japonici 10-17.
Preferred version is, Caulis Perillae 12-14; Exocarpium Citri Grandis 9-12; Herba speranskiae tuberculatae 13-15; Folium Citri tangerinae 9-10; Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 11-13; Lobed Actinostemma Herb 11-14; Pyrolusitum 10-14; Herba Schizonepetae 9-11; Folium Callicarpae Formosanae 11-14; Radix Thalictri Trichopi 10-13; Dendrobium jenkinsii Wall ex Lindl． 8-10; Ramulus et folium buddlejae davidii 13-14; Cortex schizophragmatis integrifolii radicis 10-12; Herba Polygoni japonici 12-15.
More preferably, Caulis Perillae 13; Exocarpium Citri Grandis 10.5; Herba speranskiae tuberculatae 14; Folium Citri tangerinae 9.5; Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 12; Lobed Actinostemma Herb 12.5; Pyrolusitum 12; Herba Schizonepetae 10; Folium Callicarpae Formosanae 12.5; Radix Thalictri Trichopi 11.5; Dendrobium jenkinsii Wall ex Lindl． 9; Ramulus et folium buddlejae davidii 13.5; Cortex schizophragmatis integrifolii radicis 11; Herba Polygoni japonici 13.5.
Described a kind of outer preparation method of powdering for the treatment of beriberi, step is as follows:
(1) get Exocarpium Citri Grandis and Ramulus et folium buddlejae davidii to clean, be placed in oil cauldron, constantly stir, explode and turn yellow to surface, take out, drain oil, pulverize after cooling, add Chinese liquor and stir, airtight moistening, for subsequent use;
(2) get Folium Citri tangerinae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Folium Callicarpae Formosanae roguing to clean, be placed in container, water proof micro-steamings 5-15 minute (preferably: water proof micro-steaming 8-12 minute; Be more preferably: the micro-steaming of water proof 10 minutes), take out, be cut into filament, add refined honey and mix thoroughly, infiltrate hereinafter fire drying;
(3) cleaned by pyrolusitum, knock fritter, be placed in marmite, big fire is calcined to and is popular in, and pour leaching in rice vinegar while hot into and quench, take out, dry, water flies into fine powder, and add Oleum sesami and be in harmonious proportion evenly, slow fire dries;
(4) Caulis Perillae, Herba speranskiae tuberculatae, Lobed Actinostemma Herb, Herba Schizonepetae, Radix Thalictri Trichopi, Dendrobium jenkinsii Wall ex Lindl．, Cortex schizophragmatis integrifolii radicis and Herba Polygoni japonici are cleaned remove impurity, cutting or sheet, be placed in frying pan, moderate heat heats, and when stir-frying to crude drug surface zoom, drenches into brown sugar water, continue to fry to sucrose solution is blotted, take out, cool;
(5) step (1) (2) (4) made crude drug is pulverized and sieved, mix with step (3) made crude drug, obtain outer powdering.
Described a kind of outer preparation method of powdering for the treatment of beriberi, it is that the 0.3-0.6 of crude drug quality is doubly (preferred: to add 0.4-0.5 times that Chinese liquor amount is crude drug quality that step (1) adds Chinese liquor amount; Be more preferably: add 0.45 times that Chinese liquor amount is crude drug quality).
Described a kind of outer preparation method of powdering for the treatment of beriberi, step (1) airtight moistening 12-24 minute is (preferred: airtight moistening 16-20 minute; Be more preferably: airtight moistening 18 minutes).
Described a kind of outer preparation method of powdering for the treatment of beriberi, the amount that step (2) adds refined honey is the 0.2-0.4 of crude drug quality doubly (preferred: the amount adding refined honey is 0.3 times of crude drug quality).
Described a kind of outer preparation method of powdering for the treatment of beriberi, it is the 0.4-0.6 of crude drug quality doubly (preferred: to add 0.5 times that Oleum sesami amount is crude drug quality) that step (3) adds Oleum sesami amount.
Described a kind of outer preparation method of powdering for the treatment of beriberi, it is (preferred: to pulverize 180-220 mesh sieve that step (5) pulverized 150-250 mesh sieve; Be more preferably: pulverized 200 mesh sieves).
Present invention also offers described a kind of outer application of powdering when preparing treatment beriberi for the treatment of beriberi.
A kind of outer scientific formulation of powdering for the treatment of beriberi provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, evident in efficacy, and cure rate is high, effectively can reduce relapse rate;
2, this prescription is according to Chinese medicine principle, has the effect such as disinfecting detoxifying, removing damp to relieve itching;
3, relapse rate of the present invention is low, short treating period, lasting medicine, thoroughly can effect a radical cure beriberi.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Caulis Perillae: base is former: be the stem of labiate Folium Perillae or wild Folium Perillae.Nature and flavor: acrid in the mouth; Warm in nature.Gui Jing: return spleen; Stomach; Lung meridian.Function cures mainly: regulating the flow of QI to ease the stomach; Antiabortive; And blood.Main stagnation of QI in spleen and stomach; Gastral cavity abdomen feeling of fullness, nausea is got along well, edema beriberi, and spitting of blood tells nosebleed.
Exocarpium Citri Grandis: base is former: be the outside rind of the immature fruit of Rutaceae plant Citrus grandis or Fructus Citri grandis.Chemical analysis: fruit is containing naringin, naringin unit; Peel is containing citral, geraniol, linalool, phosphorus Methyl anthranilate etc.Nature and flavor: bitter; Pungent; Temperature.Gui Jing: spleen; Lung meridian.Drying dampness to eliminate phlegm; Regulate the flow of vital energy; Help digestion.Main air is trembled with fear cough with asthma abundant expectoration; Vomiting singultus; Accumulation of food in the stomach and intes tine due to indigestion; Abdominal distention.
Herba speranskiae tuberculatae: base is former: be the herb of euphorbia plant speranskia tuberculata.Nature and flavor: pungent; Warm in nature.Gui Jing: lung; Liver Channel.Function cures mainly: expelling wind and removing dampness; Relaxing muscles and tendons to promote blood circulation; Dissipating blood stasis for subsidence of swelling; Removing toxic substances ophthalmalgia.Main air pain of dampness syndrome; Muscles and bones contracture; The disturbance of lower legs due to pathogenic cold and dampness; Lumbar strain; Paralysis; Amenorrhea; Eczema scrotum; Furuncle toxic swelling.
Folium Citri tangerinae: base is former: this product is the leaf of the multiple Fructus Citri tangerinae class such as leaf or Zhu's Fructus Citri tangerinae of rutaceae orange, can adopt at any time, dry or using fresh herb.Chemical composition: containing vitamin C in leaf.Another containing multiple kinds of carbohydrate, as glucose, fructose, sucrose, starch and cellulose etc., its content is higher when blooming, decrescence few during fruit maturation, increases again after harvesting.Various Folium Citri tangerinae is all containing volatile oil.Containing vitamin c 151 milligrams of % in the leaf of citrus reticulata“Unshiu”.Nature and flavor with return through toil, flat.Enter Liver Channel.Have soothing the liver, circulation of qi promoting, reduce phlegm, effect of detumescence poison.Cure mainly hypochondriac pain, acute mastitis, lung abscess, cough, chest and diaphragm feeling of fullness, hernia.
Radix Piperis sarmentosi (Herba Piperis Sarmentosi): base is former: be the stem of Piperaceae plant Radix Piperis sarmentosi (Herba Piperis Sarmentosi), leaf or herb.Nature and flavor: bitter; Warm in nature.Gui Jing: the heart; Lung; Spleen; Large intestine channel.Function cures mainly: expelling wind and cold; Promoting the circulation of QI to relieve pain; Active; Detumescence.Main air is trembled with fear cough with asthma; Rheumatic arthralgia; Distension and fullness in the abdomen; Dysentery; Puerperal swelling of the feet; Traumatic injury.
Lobed Actinostemma Herb: base is former: be herb or the seed of Cucurbitaceae Lobed Actinostemma Herb platymiscium Lobed Actinostemma Herb.The property of medicine: bitter, cold.Function cures mainly: inducing diuresis to remove edema, heat-clearing and toxic substances removing.Cure mainly edema, tympanites, infantile malnutrition, eczema, skin infection, venom.
Pyrolusitum: base is former: be the Ore of oxide-based mineral pyrolusite.Nature and flavor: sweet; Flat; Salty; Cold; Nontoxic.Gui Jing: kidney; Liver Channel.Function cures mainly: blood stasis removing stops blooding; Reducing swelling and alleviating pain; Promoting tissue regeneration and ulcer healing.Main traumatic injury; Incised wound is hemorrhage; Carbuncle skin infection; Burn due to hot liquid or fire.
Herba Schizonepetae: nature and flavor: pungent, tepor.Return lung, Liver Channel.There is the loose wind that induces sweat, rash, the effect of the skin ulcer that disappears.For flu, headache, measles, rubella, skin infection from the beginning of.
Folium Callicarpae Formosanae: base is former: be the leaf of dicotyledon medicine Verbenaceae callicarpa pedunculata, Callicarpa dichotoma, callicarpa cathayana Chang, Radix Callicarpae Giraldii.Nature and flavor: pained; Cool.Function cures mainly: astringing to arrest bleeding; Heat-clearing and toxic substances removing.Main hematemesis; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Gingival hemorrhage; Metrorrhagia; Skin purpura; Traumatic hemorrhage; Swollen ulcer drug; Venom; Burn.
Radix Thalictri Trichopi: base is former: be root, the rattan of moraceae plants Radix Thalictri Trichopi.Nature and flavor: taste is micro-pungent; Property is put down.Function cures mainly: expelling wind and removing dampness; Reducing swelling and alleviating pain; Removing toxic substances parasite killing.Main rheumatic arthritis; Dislocation; Acute mastitis; Furuncle; Ringworm.
Dendrobium jenkinsii Wall ex Lindl．: base is former: for the orchid family Dendrobium Sw gathers the herb of Herba Dendrobii.The property of medicine: liver, gallbladder is cool.Function cures mainly: nourishing the lung to arrest cough, tonifying-Yin and nourishing-stomach.Cure mainly cough due to lung-heat, pulmonary tuberculosis, asthma, dysentery, stomatitis, stomachache, infant malnutrition.
Ramulus et folium buddlejae davidii: base is former: be branch and leaf, the root bark of Buddlejaceae plant Buddleia davidii.Nature and flavor: pungent; Micro-hardship; Warm in nature; Poisonous.Gui Jing: the heart; Liver; Kidney channel.Function cures mainly: expelling wind and cold; Promoting blood circulation and stopping pain; Removing toxic substances parasite killing.Main cough due to wind and cold; Arthralgia pain; Traumatic injury; Carbuncle furuncle; Women's pudendal pruritus; Leprosy; Tinea pedis.
Cortex schizophragmatis integrifolii radicis: base is former: be root and the ratan of saxifragaceae plant Cortex schizophragmatis integrifolii radicis.Nature and flavor: cool; Light.Gui Jing: spleen channel.Function cures mainly: relaxing muscles and tendons and activating QI and blood in the collateral, expelling wind and activating blood circulation.Main air beriberi caused by pathogenic damp; Wind and cold arthromyodynia; Extremities joint is ached.
Herba Polygoni japonici: base is former: be the herb of polygonaceae plant Herba Polygoni japonici.Nature and flavor: pungent; Warm in nature.Function cures mainly: removing toxic substances; Pain relieving; Rash.Main skin infection swells and ache; Parasites is bitten; Diarrhoea; Dysentery; The cold pain of waist knee joint; Measles is sent out not smooth thoroughly.
embodiment 1a kind of the outer of beriberi for the treatment of is powdered, and is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Perillae 10 parts, Exocarpium Citri Grandis 8 parts, Herba speranskiae tuberculatae 11 parts, Folium Citri tangerinae 7 parts of ， Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 9 parts, Lobed Actinostemma Herb 10 parts, pyrolusitum 8 parts, Herba Schizonepetae 7 parts, Folium Callicarpae Formosanae 9 parts, Radix Thalictri Trichopi 8 parts, Dendrobium jenkinsii Wall ex Lindl． 6 parts, Ramulus et folium buddlejae davidii 11 parts, Cortex schizophragmatis integrifolii radicis 8 parts, Herba Polygoni japonici 10 parts.Above-mentioned a kind of outer preparation method of powdering for the treatment of beriberi is:
(1) get Exocarpium Citri Grandis and Ramulus et folium buddlejae davidii to clean, be placed in oil cauldron, constantly stir, explode and turn yellow to surface, take out, drain oil, pulverize after cooling, the Chinese liquor adding crude drug quality 0.3 times stirs, and airtight moistening 12 minutes is for subsequent use;
(2) get Folium Citri tangerinae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Folium Callicarpae Formosanae roguing to clean, be placed in container, the micro-steaming of water proof 5 minutes, take out, be cut into filament, add refined honey and mix thoroughly (refined honey amount is 0.2 times of crude drug quality), infiltrate hereinafter fire drying;
(3) cleaned by pyrolusitum, knock fritter, be placed in marmite, big fire is calcined to and is popular in, and pour leaching in rice vinegar while hot into and quench, take out, dry, water flies into fine powder, and the Oleum sesami adding crude drug quality 0.4 times is in harmonious proportion evenly, and slow fire dries;
(4) Caulis Perillae, Herba speranskiae tuberculatae, Lobed Actinostemma Herb, Herba Schizonepetae, Radix Thalictri Trichopi, Dendrobium jenkinsii Wall ex Lindl．, Cortex schizophragmatis integrifolii radicis and Herba Polygoni japonici are cleaned remove impurity, cutting or sheet, be placed in frying pan, moderate heat heats, and when stir-frying to crude drug surface zoom, drenches into brown sugar water, continue to fry to sucrose solution is blotted, take out, cool;
(5) step (1) (2) (4) made crude drug is pulverized 150 mesh sieves, mixed with step (3) made crude drug, obtain outer powdering.
embodiment 2a kind of the outer of beriberi for the treatment of is powdered, and is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Perillae 16 parts, Exocarpium Citri Grandis 13 parts, Herba speranskiae tuberculatae 17 parts, Folium Citri tangerinae 12 parts of ， Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 15 parts, Lobed Actinostemma Herb 15 parts, pyrolusitum 16 parts, Herba Schizonepetae 13 parts, Folium Callicarpae Formosanae 16 parts, Radix Thalictri Trichopi 15 parts, Dendrobium jenkinsii Wall ex Lindl． 12 parts, Ramulus et folium buddlejae davidii 16 parts, Cortex schizophragmatis integrifolii radicis 14 parts, Herba Polygoni japonici 17 parts.Above-mentioned a kind of outer preparation method of powdering for the treatment of beriberi is:
(1) get Exocarpium Citri Grandis and Ramulus et folium buddlejae davidii to clean, be placed in oil cauldron, constantly stir, explode and turn yellow to surface, take out, drain oil, pulverize after cooling, the Chinese liquor adding crude drug quality 0.6 times stirs, and airtight moistening 24 minutes is for subsequent use;
(2) get Folium Citri tangerinae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Folium Callicarpae Formosanae roguing to clean, be placed in container, the micro-steaming of water proof 15 minutes, take out, be cut into filament, add refined honey and mix thoroughly (refined honey amount is 0.4 times of crude drug quality), infiltrate hereinafter fire drying;
(3) cleaned by pyrolusitum, knock fritter, be placed in marmite, big fire is calcined to and is popular in, and pour leaching in rice vinegar while hot into and quench, take out, dry, water flies into fine powder, and the Oleum sesami adding crude drug quality 0.6 times is in harmonious proportion evenly, and slow fire dries;
(4) Caulis Perillae, Herba speranskiae tuberculatae, Lobed Actinostemma Herb, Herba Schizonepetae, Radix Thalictri Trichopi, Dendrobium jenkinsii Wall ex Lindl．, Cortex schizophragmatis integrifolii radicis and Herba Polygoni japonici are cleaned remove impurity, cutting or sheet, be placed in frying pan, moderate heat heats, and when stir-frying to crude drug surface zoom, drenches into brown sugar water, continue to fry to sucrose solution is blotted, take out, cool;
(5) step (1) (2) (4) made crude drug is pulverized 250 mesh sieves, mixed with step (3) made crude drug, obtain outer powdering.
Model case: xxx, women, 20 years old.Main suit: must have beriberi more than a year, toe space pachylosis is dry and cracked, has a small amount of exanthema vesiculosum, desquamation after dry, and unbearably, after scratching is violent, local oozing of blood, patient is very painful, once uses daktarin, and symptom has no improvement for pruritus.
Use outside this example gained and powder, be coated in affected part, one day 2-3 time, within seven days, be a course for the treatment of, after patient uses a course for the treatment of, beriberi symptom is obviously alleviated, and pruritus alleviates, and after adhering to two courses for the treatment of of use, beriberi is eliminated, and follows up a case by regular visits in 1 year, has no recurrence.
embodiment 3a kind of the outer of beriberi for the treatment of is powdered, and is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Perillae 12 parts, Exocarpium Citri Grandis 9 parts, Herba speranskiae tuberculatae 13 parts, Folium Citri tangerinae 9 parts of ， Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 11 parts, Lobed Actinostemma Herb 11 parts, pyrolusitum 10 parts, Herba Schizonepetae 9 parts, Folium Callicarpae Formosanae 11 parts, Radix Thalictri Trichopi 10 parts, Dendrobium jenkinsii Wall ex Lindl． 8 parts, Ramulus et folium buddlejae davidii 13 parts, Cortex schizophragmatis integrifolii radicis 10 parts, Herba Polygoni japonici 12 parts.Above-mentioned a kind of outer preparation method of powdering for the treatment of beriberi is:
(1) get Exocarpium Citri Grandis and Ramulus et folium buddlejae davidii to clean, be placed in oil cauldron, constantly stir, explode and turn yellow to surface, take out, drain oil, pulverize after cooling, the Chinese liquor adding crude drug quality 0.4 times stirs, and airtight moistening 16 minutes is for subsequent use;
(2) get Folium Citri tangerinae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Folium Callicarpae Formosanae roguing to clean, be placed in container, the micro-steaming of water proof 8 minutes, take out, be cut into filament, add refined honey and mix thoroughly (refined honey amount is 0.2 times of crude drug quality), infiltrate hereinafter fire drying;
(3) cleaned by pyrolusitum, knock fritter, be placed in marmite, big fire is calcined to and is popular in, and pour leaching in rice vinegar while hot into and quench, take out, dry, water flies into fine powder, and the Oleum sesami adding crude drug quality 0.4 times is in harmonious proportion evenly, and slow fire dries;
(4) Caulis Perillae, Herba speranskiae tuberculatae, Lobed Actinostemma Herb, Herba Schizonepetae, Radix Thalictri Trichopi, Dendrobium jenkinsii Wall ex Lindl．, Cortex schizophragmatis integrifolii radicis and Herba Polygoni japonici are cleaned remove impurity, cutting or sheet, be placed in frying pan, moderate heat heats, and when stir-frying to crude drug surface zoom, drenches into brown sugar water, continue to fry to sucrose solution is blotted, take out, cool;
(5) step (1) (2) (4) made crude drug is pulverized 180 mesh sieves, mixed with step (3) made crude drug, obtain outer powdering.
embodiment 4a kind of the outer of beriberi for the treatment of is powdered, and is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Perillae 14 parts, Exocarpium Citri Grandis 12 parts, Herba speranskiae tuberculatae 15 parts, Folium Citri tangerinae 10 parts of ， Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 13 parts, Lobed Actinostemma Herb 14 parts, pyrolusitum 14 parts, Herba Schizonepetae 11 parts, Folium Callicarpae Formosanae 14 parts, Radix Thalictri Trichopi 13 parts, Dendrobium jenkinsii Wall ex Lindl． 10 parts, Ramulus et folium buddlejae davidii 14 parts, Cortex schizophragmatis integrifolii radicis 12 parts, Herba Polygoni japonici 15 parts.Above-mentioned a kind of outer preparation method of powdering for the treatment of beriberi is:
(1) get Exocarpium Citri Grandis and Ramulus et folium buddlejae davidii to clean, be placed in oil cauldron, constantly stir, explode and turn yellow to surface, take out, drain oil, pulverize after cooling, the Chinese liquor adding crude drug quality 0.5 times stirs, and airtight moistening 20 minutes is for subsequent use;
(2) get Folium Citri tangerinae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Folium Callicarpae Formosanae roguing to clean, be placed in container, the micro-steaming of water proof 12 minutes, take out, be cut into filament, add refined honey and mix thoroughly (refined honey amount is 0.4 times of crude drug quality), infiltrate hereinafter fire drying;
(3) cleaned by pyrolusitum, knock fritter, be placed in marmite, big fire is calcined to and is popular in, and pour leaching in rice vinegar while hot into and quench, take out, dry, water flies into fine powder, and the Oleum sesami adding crude drug quality 0.6 times is in harmonious proportion evenly, and slow fire dries;
(4) Caulis Perillae, Herba speranskiae tuberculatae, Lobed Actinostemma Herb, Herba Schizonepetae, Radix Thalictri Trichopi, Dendrobium jenkinsii Wall ex Lindl．, Cortex schizophragmatis integrifolii radicis and Herba Polygoni japonici are cleaned remove impurity, cutting or sheet, be placed in frying pan, moderate heat heats, and when stir-frying to crude drug surface zoom, drenches into brown sugar water, continue to fry to sucrose solution is blotted, take out, cool;
(5) step (1) (2) (4) made crude drug is pulverized 220 mesh sieves, mixed with step (3) made crude drug, obtain outer powdering.
Model case: xxx, male, 36 years old.Main suit: before patient half a year, accidentally infected beriberi by people, toe is sewed with and festers, and many places breach, has phenomenon of casting off a skin, exposes the rotten to the corn face of cerise, very itches incomparable, night-time attack, impact sleep.
Introduce to use outside this example gained through friend and powder, being coated in affected part, one day 2-3 time, seven days is a course for the treatment of, patient is festered and is clearly better after using three days, and pruritus is alleviated, and adheres to two courses for the treatment of of use, uncomfortable disease is all eliminated, and skin returns to normally, consolidates again three days, and patient fully recovers.
embodiment 5a kind of the outer of beriberi for the treatment of is powdered, and is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Perillae 13 parts, Exocarpium Citri Grandis 10.5 parts, Herba speranskiae tuberculatae 14 parts, Folium Citri tangerinae 9.5 parts of ， Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 12 parts, Lobed Actinostemma Herb 12.5 parts, pyrolusitum 12 parts, Herba Schizonepetae 10 parts, Folium Callicarpae Formosanae 12.5 parts, Radix Thalictri Trichopi 11.5 parts, Dendrobium jenkinsii Wall ex Lindl． 9 parts, Ramulus et folium buddlejae davidii 13.5 parts, Cortex schizophragmatis integrifolii radicis 11 parts, Herba Polygoni japonici 13.5 parts.Above-mentioned a kind of outer preparation method of powdering for the treatment of beriberi is:
(1) get Exocarpium Citri Grandis and Ramulus et folium buddlejae davidii to clean, be placed in oil cauldron, constantly stir, explode and turn yellow to surface, take out, drain oil, pulverize after cooling, the Chinese liquor adding crude drug quality 0.45 times stirs, and airtight moistening 18 minutes is for subsequent use;
(2) get Folium Citri tangerinae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Folium Callicarpae Formosanae roguing to clean, be placed in container, the micro-steaming of water proof 10 minutes, take out, be cut into filament, add refined honey and mix thoroughly (refined honey amount is 0.3 times of crude drug quality), infiltrate hereinafter fire drying;
(3) cleaned by pyrolusitum, knock fritter, be placed in marmite, big fire is calcined to and is popular in, and pour leaching in rice vinegar while hot into and quench, take out, dry, water flies into fine powder, and the Oleum sesami adding crude drug quality 0.5 times is in harmonious proportion evenly, and slow fire dries;
(4) Caulis Perillae, Herba speranskiae tuberculatae, Lobed Actinostemma Herb, Herba Schizonepetae, Radix Thalictri Trichopi, Dendrobium jenkinsii Wall ex Lindl．, Cortex schizophragmatis integrifolii radicis and Herba Polygoni japonici are cleaned remove impurity, cutting or sheet, be placed in frying pan, moderate heat heats, and when stir-frying to crude drug surface zoom, drenches into brown sugar water, continue to fry to sucrose solution is blotted, take out, cool;
(5) step (1) (2) (4) made crude drug is pulverized 200 mesh sieves, mixed with step (3) made crude drug, obtain outer powdering.
test example 1a kind of clinical practice for the treatment of outer powder (embodiment 5) of beriberi of gained of the present invention:
Choose crowd: in February ,-2015 in March, 2014, according to medical case history, have typical beriberi symptom six hospital's screenings, fungus microscope examination is positive patient 289 example, age 12-64 year, 36.7 ± 3.4 years old mean age, the course of disease 3 months-10 years, wherein male patient 152 example, female patient 137 example.All patients did not use antifungal medicine in two weeks, got rid of gestation and nursing women, diabetes and severe cardiac Liver and kidney patient, and treatments period patient needs further consultation on time.
Before test, patient is divided into two groups at random, experimental group 174 example and matched group 115 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group uses products obtained therefrom of the present invention, is coated in affected part, one day 2-3 time, within seven days, is a course for the treatment of; Matched group uses other conventional medicines (daktarin, beriberi king, ZUGUANG SAN etc.).Treatments period carries out Continuous Observation to two groups of patients, record symptom (pimple, vesicle, desquamation, pruritus, chap) improvement situation, onset time and having no adverse reaction.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptom disappearance, and skin lesion recovers, and fungus microscope examination is negative; (2) effective: clinical symptoms is obviously alleviated, skin lesion disappears 60%, and fungus microscope examination is positive (visible a small amount of mycelia); (3) effective: clinical symptom relief, skin lesion disappears more than 30%, and fungus microscope examination is positive (easily seeing fungal spore and mycelia); (4) invalid: clinical symptoms and microscopy are substantially without improvement.
Clinical effectiveness: after the treatment of two courses for the treatment of, experimental group cures 126 examples (72.4%), effective 25 examples (14.4%), effective 19 examples (10.9%), invalid 4 examples (2.3%), and total effective rate is 97.7%; Matched group cures 63 examples (54.8%), effective 19 examples (16.5%), effective 12 examples (10.4%), and invalid 21 examples (18.3%), total effective rate is 81.7%.It can thus be appreciated that matched group is significantly lower than the therapeutic effect of experimental group, and illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
The Chinese medicine used in the present invention, Caulis Perillae can regulating the flow of QI to ease the stomach, Exocarpium Citri Grandis can drying dampness to eliminate phlegm, Herba speranskiae tuberculatae, Radix Thalictri Trichopi can expelling wind and removing dampness, Folium Citri tangerinae can subduing swelling and detoxicating; Radix Piperis sarmentosi (Herba Piperis Sarmentosi) can promoting the circulation of QI to relieve pain, and Lobed Actinostemma Herb can heat-clearing and toxic substances removing, and pyrolusitum can promoting tissue regeneration and ulcer healing, Herba Schizonepetae can induce sweat loose wind, Folium Callicarpae Formosanae can astringing to arrest bleeding, and Dendrobium jenkinsii Wall ex Lindl． can tonifying-Yin and nourishing-stomach, and Ramulus et folium buddlejae davidii can promoting blood circulation and stopping pain, Cortex schizophragmatis integrifolii radicis can relaxing muscles and tendons and activating QI and blood in the collateral, Herba Polygoni japonici can pain relieving rash, and multiple medical material synergism, plays effect of expelling wind and removing dampness, promoting tissue regeneration and ulcer healing, heat-clearing and toxic substances removing altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the outer of beriberi and powder for one kind, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Caulis Perillae 10-16; Exocarpium Citri Grandis 8-13; Herba speranskiae tuberculatae 11-17; Folium Citri tangerinae 7-12; Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 9-15; Lobed Actinostemma Herb 10-15; Pyrolusitum 8-16; Herba Schizonepetae 7-13; Folium Callicarpae Formosanae 9-16; Radix Thalictri Trichopi 8-15; Dendrobium jenkinsii Wall ex Lindl． 6-12; Ramulus et folium buddlejae davidii 11-16; Cortex schizophragmatis integrifolii radicis 8-14; Herba Polygoni japonici 10-17.
2. a kind of the outer of beriberi for the treatment of is powdered as claimed in claim 1, it is characterized in that, Caulis Perillae 12-14; Exocarpium Citri Grandis 9-12; Herba speranskiae tuberculatae 13-15; Folium Citri tangerinae 9-10; Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 11-13; Lobed Actinostemma Herb 11-14; Pyrolusitum 10-14; Herba Schizonepetae 9-11; Folium Callicarpae Formosanae 11-14; Radix Thalictri Trichopi 10-13; Dendrobium jenkinsii Wall ex Lindl． 8-10; Ramulus et folium buddlejae davidii 13-14; Cortex schizophragmatis integrifolii radicis 10-12; Herba Polygoni japonici 12-15.
3. a kind of the outer of beriberi for the treatment of is powdered as claimed in claim 1, it is characterized in that, Caulis Perillae 13; Exocarpium Citri Grandis 10.5; Herba speranskiae tuberculatae 14; Folium Citri tangerinae 9.5; Radix Piperis sarmentosi (Herba Piperis Sarmentosi) 12; Lobed Actinostemma Herb 12.5; Pyrolusitum 12; Herba Schizonepetae 10; Folium Callicarpae Formosanae 12.5; Radix Thalictri Trichopi 11.5; Dendrobium jenkinsii Wall ex Lindl． 9; Ramulus et folium buddlejae davidii 13.5; Cortex schizophragmatis integrifolii radicis 11; Herba Polygoni japonici 13.5.
4. a kind of outer preparation method of powdering for the treatment of beriberi as described in as arbitrary in claim 1-3, it is characterized in that, step is as follows:
(1) get Exocarpium Citri Grandis and Ramulus et folium buddlejae davidii to clean, be placed in oil cauldron, constantly stir, explode and turn yellow to surface, take out, drain oil, pulverize after cooling, add Chinese liquor and stir, airtight moistening, for subsequent use;
(2) get Folium Citri tangerinae, Radix Piperis sarmentosi (Herba Piperis Sarmentosi) and Folium Callicarpae Formosanae roguing to clean, be placed in container, water proof micro-steamings 5-15 minute (preferably: water proof micro-steaming 8-12 minute; Be more preferably: the micro-steaming of water proof 10 minutes), take out, be cut into filament, add refined honey and mix thoroughly, infiltrate hereinafter fire drying;
(3) cleaned by pyrolusitum, knock fritter, be placed in marmite, big fire is calcined to and is popular in, and pour leaching in rice vinegar while hot into and quench, take out, dry, water flies into fine powder, and add Oleum sesami and be in harmonious proportion evenly, slow fire dries;
(4) Caulis Perillae, Herba speranskiae tuberculatae, Lobed Actinostemma Herb, Herba Schizonepetae, Radix Thalictri Trichopi, Dendrobium jenkinsii Wall ex Lindl．, Cortex schizophragmatis integrifolii radicis and Herba Polygoni japonici are cleaned remove impurity, cutting or sheet, be placed in frying pan, moderate heat heats, and when stir-frying to crude drug surface zoom, drenches into brown sugar water, continue to fry to sucrose solution is blotted, take out, cool;
(5) step (1) (2) (4) made crude drug is pulverized and sieved, mix with step (3) made crude drug, obtain outer powdering.
5. a kind of outer preparation method of powdering for the treatment of beriberi as claimed in claim 4, is characterized in that, step (1) add Chinese liquor amount be the 0.3-0.6 of crude drug quality doubly (preferred: add Chinese liquor amount be the 0.4-0.5 of crude drug quality doubly; Be more preferably: add 0.45 times that Chinese liquor amount is crude drug quality).
6. a kind of outer preparation method of powdering for the treatment of beriberi as claimed in claim 4, is characterized in that, step (1) airtight moistening 12-24 minute is (preferred: airtight moistening 16-20 minute; Be more preferably: airtight moistening 18 minutes).
7. a kind of outer preparation method of powdering for the treatment of beriberi as claimed in claim 4, is characterized in that, the amount that step (2) adds refined honey is the 0.2-0.4 of crude drug quality doubly (preferred: the amount adding refined honey is 0.3 times of crude drug quality).
8. a kind of outer preparation method of powdering for the treatment of beriberi as claimed in claim 4, is characterized in that, it is the 0.4-0.6 of crude drug quality doubly (preferred: to add 0.5 times that Oleum sesami amount is crude drug quality) that step (3) adds Oleum sesami amount.
9. a kind of outer preparation method of powdering for the treatment of beriberi as claimed in claim 4, is characterized in that, it is (preferred: to pulverize 180-220 mesh sieve that step (5) pulverized 150-250 mesh sieve; Be more preferably: pulverized 200 mesh sieves).
10. a kind of outer application of powdering when preparing treatment beriberi for the treatment of beriberi as described in as arbitrary in claim 1-3.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105998770A (en) * | 2016-05-25 | 2016-10-12 | 王忠喜 | Foot-bath salt for assisting dermatophytosis treatment and preparation method thereof |
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Non-Patent Citations (1)
| Title |
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| 刘燕兰: "杀癣方联合复方酮康唑乳膏治疗手足癣50例疗效观察", 《中国中西医结合皮肤性病学杂志》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998770A (en) * | 2016-05-25 | 2016-10-12 | 王忠喜 | Foot-bath salt for assisting dermatophytosis treatment and preparation method thereof |
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