CN105126028A - Preparation for treating daftness and preparation method of preparation - Google Patents

Preparation for treating daftness and preparation method of preparation Download PDF

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CN105126028A
CN105126028A CN201510611708.5A CN201510611708A CN105126028A CN 105126028 A CN105126028 A CN 105126028A CN 201510611708 A CN201510611708 A CN 201510611708A CN 105126028 A CN105126028 A CN 105126028A
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不公告发明人
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Abstract

The invention discloses a preparation for treating daftness. The preparation is mainly prepared from the following active pharmaceutical ingredients in parts by weight: 10 to 16 parts of corn stigma, 7 to 13 parts of helleborus thibetanus, 9 to 12 parts of exocarpium, 11 to 16 parts of lilies, 7 to 14 parts of pearl, 8 to 13 parts of turnip, 10 to 14 parts of ashycoloured ironweed herb, 7 to 12 parts of Indian epimeredi herb, 9 to 14 parts of bilobed grewia root stems and leaves, 6 to 12 parts of acorus graminens soland, 9 to 15 parts of common adenostema herb, 7 to 11 parts of fokien angiopteris rhizome, 10 to 15 parts of radix curcumae, 6 to 13 parts of aglaia odorata and 8 to 12 parts of farges fir cone. The preparation is prepared through the summarization of clinic practice for many years; the effects of regulating Qi, promoting blood circulation, nourishing heart and tranquilizing mind are achieved; the curative effect is obvious.

Description

A kind of for curing demented preparation and method for making
Technical field
The present invention relates to traditional Chinese medicine field, particularly relating to a kind of for curing demented preparation and method for making.
Background technology
The insane disease of demented finger.Insane, show as depressive state, apathy, being reticent and dementia, speaking incoherently, do not know hungry full, very then sudden syncope with rigidity's direct-view, belongs to deficiency syndrome.Sick by mental disorder pent-up, or caused by deficiency of both the heart and spleen.Mad, show as excitatory state, stir up a disturbance not peaceful, clothing Bu Convergence, hits and swears at people, and song ceaselessly laughing, many anger, very then exceedes room on wall, true card.Sick excessively high by yang-energy, the mind is more caused outward.Manic-depressive psychosis has a strong impact on minimal invasive treatment, and lasting obvious exception all can appear in activity, can not learn normally, works, live, and has the action behavior of committing suiside or attacking, injuring other people time serious.
Publication No. CN104547699A(application number 201510008624.2) Chinese patent literature disclose and a kind ofly treat demented Chinese medicine preparation, be made up of following crude drug, Radix Codonopsis 15 grams, the Radix Astragali 20 grams, Radix Ginseng 3 grams, Poria cum Radix Pini 15 grams, process 6 grams, Radix Glycyrrhizae, Radix Rehmanniae 10 grams, Fructus Aurantii 10 grams, Pericarpium Citri Reticulatae 6 grams, Rhizoma Pinelliae Preparatum 12 grams, Caulis Bambusae In Taenia 10 grams, Arisaema Cum Bile 10 grams, Fructus Trichosanthis 15 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Rhizoma Cyperi 12 grams, 12 grams, Semen Persicae.Constipation person, adds Radix Et Rhizoma Rhei 6 grams (under rear), 6 grams, Natrii Sulfas; The hot person of expectorant, adds Radix Scutellariae 10 grams, Fructus Gardeniae 10 grams; Insomniac, adds Semen Ziziphi Spinosae 15 grams, Radix Polygalae 10 grams.Publication No. CN104383463A(application number 201410754692.9) Chinese patent literature disclose and be a kind ofly used for the treatment of demented Chinese medicine preparation, be prepared from by the medical material of following weight proportion: little Pumex 2 parts, 2 parts, Flos Mume brain, Borneolum Syntheticum 2 parts, Cino Da Pistoia 2 parts, Calculus Canitis 12 parts, Herba Agrimoniae 5 parts, Lignum Aquilariae Resinatum 15 parts, RADIX CURCUMAE 4 parts, ammoniac 3 parts, Oreas martiana (Hopp. Et Hornsch.) Brid. 2 parts.Publication No. CN102793894A(application number 201210324874.3) Chinese patent literature disclose and a kind ofly treat demented Chinese medicine.The Chinese medicine that this treatment is demented, with Radix Musae, Radix Et Rhizoma Rhei, Fructus Gardeniae, Massa Medicata Fermentata, Radix Sophorae Flavescentis, Herba Menthae, trichosanthes seed, Fructus Crataegi, Radix Curcumae, the Rhizoma Anemarrhenae, Bulbus Lilii, Radix Rehmanniae, Poria, Os Draconis, Folium Bambusae and Terra Flava Usta for raw material, formulated according to certain weight proportion.
This disease of western medicine is main mainly with tranquillizing and allaying excitement, cannot eradicate, long-term taking, easily produce larger side effect and dependency, and therapeutic effect is bad, and adopt Chinese medicine method, easier treating both the principal and secondary aspects of a disease, prevents disease relapse.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take safe and applicable wide for curing demented preparation and method for making.
Technical scheme of the present invention is:
For curing a demented preparation, being prepared from primarily of following bulk drugs, being mass parts: Stigma Maydis 10-16; Radix Chimonanthi praecocis 7-13; Exocarpium Citri Grandis 9-12; Flos Lilii viriduli 11-16; Concha Margaritifera 7-14; Radix Brassicae rapae 8-13; Herba Vernoniae Cinereae 10-14; Fail clothing 7-12; Radix grewiae bilobae 9-14; Rhizoma Anemones Altaicae 6-12; Herba Adenostemmatis 9-15; Rhizoma Angiopteridis Fokiensis 7-11; Radix Curcumae 10-15; Flos Aglaiae Odoratae 6-13; Strobilus Abietis Fargesii 8-12.
Preferred version is, Stigma Maydis 12-14; Radix Chimonanthi praecocis 9-11; Exocarpium Citri Grandis 10-11; Flos Lilii viriduli 12-15; Concha Margaritifera 9-12; Radix Brassicae rapae 10-11; Herba Vernoniae Cinereae 11-13; Fail clothing 9-10; Radix grewiae bilobae 10-13; Rhizoma Anemones Altaicae 8-10; Herba Adenostemmatis 11-13; Rhizoma Angiopteridis Fokiensis 8-10; Radix Curcumae 11-14; Flos Aglaiae Odoratae 8-11; Strobilus Abietis Fargesii 9-11.
More preferably, Stigma Maydis 13; Radix Chimonanthi praecocis 10; Exocarpium Citri Grandis 10.5; Flos Lilii viriduli 13.5; Concha Margaritifera 10.5; Radix Brassicae rapae 10.5; Herba Vernoniae Cinereae 12; To fail clothing 9.5; Radix grewiae bilobae 11.5; Rhizoma Anemones Altaicae 9; Herba Adenostemmatis 12; Rhizoma Angiopteridis Fokiensis 9; Radix Curcumae 12.5; Flos Aglaiae Odoratae 9.5; Strobilus Abietis Fargesii 10.
Described is a kind of for curing demented preparation, and be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse steam 14-22 minute (preferred: to add mulse and steam 16-20 minute; Be more preferably: add mulse and steam 18 minutes), take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 10-20 minute (preferably: intense fire forges 12-18 minute; Be more preferably: intense fire forges 15 minutes), take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, decoct with water together with Radix grewiae bilobae to boiling with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 15-25 minute (preferred: to continue 18-22 minute; Be more preferably: continue 20 minutes), after filtration, collect filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, be added in step (4) gained filtrate, big fire is boiled to boiling, Guan Huohou, leaves standstill 5 minutes, filters, and collects filtrate, obtains decoction.
Described a kind of preparation method for curing demented preparation decoction, the 7-9 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 7.5-8.5 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 8 times of boiled crude drug quality).
Described is a kind of for curing demented preparation, and be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse steam 14-22 minute (preferred: to add mulse and steam 16-20 minute; Be more preferably: add mulse and steam 18 minutes), take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 10-20 minute (preferably: intense fire forges 12-18 minute; Be more preferably: intense fire forges 15 minutes), take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, add the soak by water of boiled crude drug quality 7 times to seethe with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 15-25 minute (preferred: lasting 18-22 minute; Be more preferably: continue 20 minutes), after filtration, collect filtrate;
(5) will be pulverized by step (1) (2) (3) made raw material, mix with step (4) gained filtrate, heating is concentrated into clear paste, adds adjuvant refined honey, stirs, obtain unguentum.
Described a kind of preparation method for curing demented preparation unguentum, the amount that step (5) adds adjuvant refined honey is the 0.3-0.5 of clear paste quality doubly (preferred: the amount adding adjuvant refined honey is 0.4 times of clear paste quality).
Described is a kind of for curing demented preparation, and be made into pharmaceutically acceptable electuary, its preparation method is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse steam 14-22 minute (preferred: to add mulse and steam 16-20 minute; Be more preferably: add mulse and steam 18 minutes), take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 10-20 minute (preferably: intense fire forges 12-18 minute; Be more preferably: intense fire forges 15 minutes), take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, add the soak by water of boiled crude drug quality 7 times to seethe with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 15-25 minute (preferred: lasting 18-22 minute; Be more preferably: continue 20 minutes), after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverizes and sieves dry thing, makes medicated powder, obtain electuary together with step (1) (2) (3) made crude drug.
Described a kind of preparation method for curing demented preparation electuary, it is (preferred: to pulverize 160-200 mesh sieve that step (5) pulverized 120-240 mesh sieve; Be more preferably: pulverized 180 mesh sieves).
Described is a kind of for curing demented preparation, and be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse steam 14-22 minute (preferred: to add mulse and steam 16-20 minute; Be more preferably: add mulse and steam 18 minutes), take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 10-20 minute (preferably: intense fire forges 12-18 minute; Be more preferably: intense fire forges 15 minutes), take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, add the soak by water of boiled crude drug quality 7 times to seethe with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 15-25 minute (preferred: lasting 18-22 minute; Be more preferably: continue 20 minutes), after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverized 80-140 mesh sieve (preferred: to pulverize 100-120 mesh sieve together with step (1) (2) (3) made crude drug by dry thing; Be more preferably: pulverized 110 mesh sieves), gained medicated powder is packed in capsule, obtains capsule.
Described a kind of preparation method for curing demented preparation capsule, in the every capsules of step (5), contained medicated powder weight is that 0.3-0.5g(is preferred: in every capsules, contained medicated powder weight is 0.4g).
Provided by the invention a kind of for curing demented pharmaceutical formulation science, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can reduce relapse rate;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of vital energy regualting and blood circulation-promoting, mind tranquilizing and the heart calming;
3, Chinese crude drug selected by the present invention, safety has no side effect, can long-term taking, can regulate patient body function.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Stigma Maydis: base is former: be the zeistic style of grass and stigma.Nature and flavor: sweet in the mouth; Light; Property is put down.Gui Jing: kidney; Stomach; Liver; Gallbladder meridian.Function cures mainly: inducing diuresis to remove edema; Liver heat removing function of gallbladder promoting.Main edema; Dribbling urination; Jaundice; Cholecystitis; Cholelithiasis; Hypertension; Diabetes; Galactostasis.
Radix Chimonanthi praecocis: base is former: be the root of Calycanthaceae wax prunus mume (sieb.) sieb.et zucc..Nature and flavor: acrid in the mouth; Warm in nature; Poisonous.Gui Jing: liver; Lung meridian.Function cures mainly: wind-expelling pain-stopping; Vital energy regualting and blood circulation-promoting; Relieving cough and asthma.Main air pain of dampness syndrome; Anemofrigid cold; Traumatic injury; Epigastric pain; Asthma; Epersalgia cough; Furuncle swelling toxin.
Exocarpium Citri Grandis: base is former: be the outside rind of the immature fruit of Rutaceae plant Citrus grandis or Fructus Citri grandis.Chemical analysis: fruit is containing naringin, naringin unit; Peel is containing citral, geraniol, linalool, phosphorus Methyl anthranilate etc.Nature and flavor: bitter; Pungent; Temperature.Gui Jing: spleen; Lung meridian.Drying dampness to eliminate phlegm; Regulate the flow of vital energy; Help digestion.Main air is trembled with fear cough with asthma abundant expectoration; Vomiting singultus; Accumulation of food in the stomach and intes tine due to indigestion; Abdominal distention.
Flos Lilii viriduli: base is former: be the flower of liliaceous plant Bulbus Lilii, tiger lily, Bulbus lilii concoloris or Bulbus Lilii.Nature and flavor: sweet; Bitter; Be slightly cold.Gui Jing: lung.Function cures mainly: clearing heat and moistening lung; Mind tranquilizing and the heart calming.Main cough expectorant is few or sticky; Dizzy; Uneasy sleeping at night; It bleb eczema.
Concha Margaritifera: base is former: be the nacreous layer of Pteriidae animal Margarita, geneva pearl pearl shellfish or several mussel shell of Unionidae animal.Chemical analysis: in the shell of schistodesmus lampreyanus, containing calcium carbonate more than 90%, organic matter about 0.34%; Still containing a small amount of magnesium, ferrum, silicate, sulfate, phosphate and chloride.After calcining, carbonate decomposition, produce calcium oxide etc., organic matter is then destroyed.Nature and flavor: salty are cool.Gui Jing: " Chinese medicine voluminous dictionary ": " enter the heart, liver two warp." function cures mainly: suppressing the hyperactive liver, YANG hyperactivity suppressing, arresting convulsion, hemostasis.Control dizziness, tinnitus, cardiopalmus, insomnia, demented, infantile convulsion, spits blood, epistaxis, metrorrhagia.
Radix Brassicae rapae: base is former: be root and the leaf of crucifer Radix Brassicae rapae.Nature and flavor: bitter; Pungent; Sweet; Temperature.Gui Jing: the heart; Lung; Spleen; Stomach warp.Function cures mainly: removing stagnancy of indigested food and making QI downward, removing toxic substances and promoting subsidence of swelling.Main indigestion; Trusted subordinate's cold type of pain; Cough; Furuncle carbuncle.
Herba Vernoniae Cinereae: base is former: be herb or the root of feverfew Herba Vernoniae Cinereae.Nature and flavor: bitter in the mouth; Pungent; Cool in nature.Function cures mainly: wind and heat dispersing; Dehumidifying; Removing toxic substances.Main sense heating; Cough; Acute icterohepatitis; Damp-heat diarrhea; Stagnant in vain; Parent's pyogenic infections from tumour or sore; Mastitis; Rhinitis; Venom.
To fail clothing: base is former: be the herb of the wide Radix Saposhnikoviae of Labiatae wide Radix Saposhnikoviae platymiscium.The property of medicine: pungent, bitter, flat.Function cures mainly: wind-damp dispelling, relieving heat toxin.Cure mainly cold, fever, rheumatic arthralgia, carbuncle sore tumefacting virus, skin eczema, worm venom.
Radix grewiae bilobae: base is former: be the Herb of Tiliaceae plant bilobed grewia.Nature and flavor: sweet; Bitter; Temperature.Gui Jing: liver; Spleen; Stomach warp.Function cures mainly: invigorating the spleen and benefiting QI; Expelling wind and removing dampness; Treating spontaneous emission and leukorrhagia.Main insufficiency of the spleen lack of appetite; Proctoptosis of a specified duration; Infantile malnutrition; Ascariasis; Rheumatic arthralgia; Seminal emission; Metrorrhagia; Leukorrhagia; Uterine prolapse.
Rhizoma Anemones Altaicae: base is former: be the rhizome of Ranunculaceae thimbleweed anemone altaica.Composition: rhizome fatty acids: Palmic acid, succinic acid, 5-hydroxylevulinic acid, hexadecanoic acid and 9,12-octadecadienoic acid, Anemonin etc.The property of medicine: pungent, temperature.GUIXIN, liver, spleen channel.Function cures mainly: waking up the patient from unconsciousness by dissipating phlegm, and expelling wind and removing dampness helps digestion and is amusing, removing toxic substances.Cure mainly calentura coma, epilepsy, deafness with qi stagnation, dreaminess is forgetful, rheumatic arthralgia, and gastral cavity uncomfortable in chest is swollen, carbuncle, scabies.Compatibility and incompatibility of drugs: hyperactivity of YANG due to deficiency of YIN, irritated hyperhidrosis, the careful clothes of essence cunning person.
Herba Adenostemmatis: base is former: be the herb of feverfew adenostemma laveniaKuntze.Nature and flavor: acrid in the mouth; Micro-hardship; Property is shied.Function cures mainly: heat-clearing and toxic substances removing; Expelling wind and removing dampness.Main cold, fever; Icterohepatitis; Cough due to lung-heat; Laryngopharynx swelling and pain; Beriberoid pyretic arthralgia; Acute mastitis; Carbuncle furuncle; Venom.
Rhizoma Angiopteridis Fokiensis: base is former: be the rhizome of Angiopteridaceae plant Fujian kwan-yin seat lotus.Nature and flavor: bitter; Cold; Cool.Gui Jing: the heart; Lung meridian.Function cures mainly: clearing away heat and cooling blood; Hemostasis by removing blood stasis; Analgesia is calmed the nerves.Main mumps; Carbuncle sore tumefacting virus; Venom; Treating swelling and pain by traumatic injury; Traumatic hemorrhage; Metrorrhagia; Acute mastitis; Rheumatic arthralgia; Puerperal abdonimal pain; Vexed insomnia.
Radix Curcumae: base is former: be the tuber of zingiberaceous plant Rhizoma Curcumae Longae, Radix Curcumae or Rhizoma Curcumae.Property pungent, bitter, cold.Return liver, the heart, lung meridian.Can regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Be generally used for amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
Flos Aglaiae Odoratae: base is former: be the branch and leaf of Meliaceae plant Flos Aglaiae Odoratae.Nature and flavor: pungent; Tepor.Gui Jing: lung; Stomach; Liver Channel.Function cures mainly: wind-damp dispelling; Dissipating blood stasis swells.Main rheumatic arthritis; Traumatic injury; Swollen ulcer drug.
Strobilus Abietis Fargesii: base is former: be the cone of pinaceae plant Qin fir.Nature and flavor: sweet; Puckery; Micro-pungent; Property is put down.Function cures mainly: suppressing the hyperactive liver to relieve the wind syndrome; Regulating menstruation and activating blood; Leukorrhagia stopping.Main hypertension pain; Headache; Dizzy; Irritability; Menoxenia; Metrorrhagia; Leukorrhagia.
embodiment 1for curing a demented preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Stigma Maydis 10 parts, Radix Chimonanthi praecocis 7 parts, Exocarpium Citri Grandis 9 parts, Flos Lilii viriduli 11 parts, Concha Margaritifera 7 parts, Radix Brassicae rapae 8 parts, Herba Vernoniae Cinereae 10 parts, 7 parts, clothing of failing, Radix grewiae bilobae 9 parts, Rhizoma Anemones Altaicae 6 parts, Herba Adenostemmatis 9 parts, Rhizoma Angiopteridis Fokiensis 7 parts, Radix Curcumae 10 parts, Flos Aglaiae Odoratae 6 parts, Strobilus Abietis Fargesii 8 parts.Above-mentioned a kind of preparation method for curing demented preparation decoction is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse and steam 18 minutes, take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 15 minutes, and take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, decoct with water to seethe with excitement (amount of water is 8 times of boiled crude drug quality) together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 20 minutes, after filtration, collect filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, be added in step (4) gained filtrate, big fire is boiled to boiling, Guan Huohou, leaves standstill 5 minutes, filters, and collects filtrate, obtains decoction.
embodiment 2for curing a demented preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Stigma Maydis 16 parts, Radix Chimonanthi praecocis 13 parts, Exocarpium Citri Grandis 12 parts, Flos Lilii viriduli 16 parts, Concha Margaritifera 14 parts, Radix Brassicae rapae 13 parts, Herba Vernoniae Cinereae 14 parts, 12 parts, clothing of failing, Radix grewiae bilobae 14 parts, Rhizoma Anemones Altaicae 12 parts, Herba Adenostemmatis 15 parts, Rhizoma Angiopteridis Fokiensis 11 parts, Radix Curcumae 15 parts, Flos Aglaiae Odoratae 13 parts, Strobilus Abietis Fargesii 12 parts.Above-mentioned a kind of preparation method for curing demented preparation unguentum is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse and steam 18 minutes, take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 15 minutes, and take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, the soak by water of boiled crude drug quality 7 times is added to seething with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 20 minutes, after filtration, collect filtrate;
(5) will be pulverized by step (1) (2) (3) made raw material, mix with step (4) gained filtrate, heating is concentrated into clear paste, adds the adjuvant refined honey of clear paste quality 0.4 times, stirs, obtain unguentum.
Model case: xxx, women, 24 years old.Household main suit: emotional instability, being irritable and getting angry easily, cannot focus one's attention on; Medical history: patient is in unemployed, emotional lability, laughs of occasionally wailing, during beginning, household does not note, after realize that patient mental's state is not right, often murmur to oneself, stare blankly alone, send to examination in hospital, it is demented that doctor is diagnosed as genus.
Take this example gained unguentum, each 6-10g, warm boiled water, one day twice, within ten days, be a course for the treatment of, after patient takes a course for the treatment of, sleep quality obviously promotes, and behavior recovers normal substantially, after adhering to taking three courses for the treatment of, patient's look is surely stabilized, behavior without exception, and patient fully recovers.
embodiment 3for curing a demented preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Stigma Maydis 12 parts, Radix Chimonanthi praecocis 9 parts, Exocarpium Citri Grandis 10 parts, Flos Lilii viriduli 12 parts, Concha Margaritifera 9 parts, Radix Brassicae rapae 10 parts, Herba Vernoniae Cinereae 11 parts, 9 parts, clothing of failing, Radix grewiae bilobae 10 parts, Rhizoma Anemones Altaicae 8 parts, Herba Adenostemmatis 11 parts, Rhizoma Angiopteridis Fokiensis 8 parts, Radix Curcumae 11 parts, Flos Aglaiae Odoratae 8 parts, Strobilus Abietis Fargesii 9 parts.Above-mentioned a kind of preparation method for curing demented preparation electuary is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse and steam 18 minutes, take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 15 minutes, and take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, the soak by water of boiled crude drug quality 7 times is added to seething with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 20 minutes, after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverized 180 mesh sieves by dry thing, and made medicated powder, obtain electuary together with step (1) (2) (3) made crude drug.
Model case: xxx, women, 19 years old.Medical history: patient closes on college entrance examination, stress is comparatively large, and mood is not good enough, and meet with again household and do not understand, overwork, all day is depressed, poor sleeping quality, dizzy, and appetite declines, and stimulating a little, have Mild Violence to be inclined to, is demented through hospital diagnosis.
Recommend to take this example gained electuary, each 3-4g, warm boiled water through people, one day twice ten days is a course for the treatment of, after patient takes two courses for the treatment of, spirit takes a turn for the better gradually, link up well with father and mother, of a sanguine disposition, after adhering to taking three courses for the treatment of, patient is without other uncomfortable diseases, recover normal, follow up a case by regular visits in 1 year, the state of an illness does not recur again.
embodiment 4for curing a demented preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Stigma Maydis 14 parts, Radix Chimonanthi praecocis 11 parts, Exocarpium Citri Grandis 11 parts, Flos Lilii viriduli 15 parts, Concha Margaritifera 12 parts, Radix Brassicae rapae 11 parts, Herba Vernoniae Cinereae 13 parts, 10 parts, clothing of failing, Radix grewiae bilobae 13 parts, Rhizoma Anemones Altaicae 10 parts, Herba Adenostemmatis 13 parts, Rhizoma Angiopteridis Fokiensis 10 parts, Radix Curcumae 14 parts, Flos Aglaiae Odoratae 11 parts, Strobilus Abietis Fargesii 11 parts.Above-mentioned a kind of preparation method for curing demented preparation capsule is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse and steam 18 minutes, take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 15 minutes, and take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, the soak by water of boiled crude drug quality 7 times is added to seething with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 20 minutes, after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverized 110 mesh sieves by dry thing, was packed in capsule by gained medicated powder together with step (1) (2) (3) made crude drug, and in every capsules, contained medicated powder weight is 0.4g, obtains capsule.
Model case: xxx, women, 42 years old.Main suit: rattiness, insomnia and dreamful sleep, inappetence; Medical history: patient closely over the past half year, because of various pressure compel, cause mood irritated, rattiness, even curses and beats other people time serious, breaks article, to hospital diagnosis, is diagnosed as demented, once treats repeatedly, fast during state of an illness fashion.
This example gained capsule is taken, each 3-4 grain, warm boiled water under the introduction of friend, one day twice, within ten days, be a course for the treatment of, after patient takes a course for the treatment of, disposition flattens surely, the symptoms such as insomnia and dreamful sleep are improved, adhere to taking two courses for the treatment of, patient's appetite recovers normal, uncomfortable without other, after consolidating again a course for the treatment of, patient recovers normal reason.
embodiment 5for curing a demented preparation, be prepared from (every part of 10g) primarily of following bulk drugs: Stigma Maydis 13 parts, Radix Chimonanthi praecocis 10 parts, Exocarpium Citri Grandis 10.5 parts, Flos Lilii viriduli 13.5 parts, Concha Margaritifera 10.5 parts, Radix Brassicae rapae 10.5 parts, Herba Vernoniae Cinereae 12 parts, 9.5 parts, clothing of failing, Radix grewiae bilobae 11.5 parts, Rhizoma Anemones Altaicae 9 parts, Herba Adenostemmatis 12 parts, Rhizoma Angiopteridis Fokiensis 9 parts, Radix Curcumae 12.5 parts, Flos Aglaiae Odoratae 9.5 parts, Strobilus Abietis Fargesii 10 parts.Above-mentioned a kind of preparation method for curing demented preparation decoction is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse and steam 18 minutes, take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 15 minutes, and take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, decoct with water to seethe with excitement (amount of water is 8 times of boiled crude drug quality) together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 20 minutes, after filtration, collect filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, be added in step (4) gained filtrate, big fire is boiled to boiling, Guan Huohou, leaves standstill 5 minutes, filters, and collects filtrate, obtains decoction.
test example 1a kind of clinical practice for curing demented preparation (embodiment 5) of gained of the present invention:
Choose crowd: in April ,-2015 in March, 2014, according to medical case history, be diagnosed as demented patient 316 example six hospitals' screenings, age 16-65 year, 36.5 ± 2.3 years old mean age, the course of disease 2 months-4 years, wherein male patient 124 example, female patient 192 example.
Before test, patient is divided into two groups at random, experimental group 160 example and matched group 156 routine, two groups in age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 250-350ml, one day twice, warmly takes, and within ten days, is a course for the treatment of; Matched group takes other conventional medicines (s).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptom disappearance, and language, manner are normal, and look is stabilized, can normal process daily pursuits, drug withdrawal 6 months, and the state of an illness is without repeatedly; (2) effective: clinical symptoms disappears substantially, look is stabilized, and language, manner is normal or obviously improve, drug withdrawal 6 months, and the state of an illness is without repeatedly; (3) effective: clinical symptom relief, look, language, manner make moderate progress, drug withdrawal 6 months, and the state of an illness is without repeatedly; (4) invalid: clinical symptoms even increases the weight of without alleviation.Total effective rate=cure rate+obvious effective rate+effective percentage.
Clinical effectiveness: after the taking medicine of three courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the total effective rate of experimental group is 96.9%, and the total effective rate 82.1% of matched group, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.Treatments period, two groups of patients are and occur any untoward reaction, illustrate that products obtained therefrom of the present invention has no side effect safely.
The Chinese medicine used in the present invention, the Stigma Maydis of liver heat removing function of gallbladder promoting, the Radix Chimonanthi praecocis of vital energy regualting and blood circulation-promoting, the Exocarpium Citri Grandis of drying dampness to eliminate phlegm, the Flos Lilii viriduli of mind tranquilizing and the heart calming, the Concha Margaritifera of suppressing the hyperactive liver and subsiding YANG, the Radix Brassicae rapae of removing stagnancy of indigested food and making QI downward, the Herba Vernoniae Cinereae of wind and heat dispersing, clothing of failing, the Radix grewiae bilobae of invigorating the spleen and benefiting QI, the Rhizoma Anemones Altaicae of waking up the patient from unconsciousness by dissipating phlegm, the Herba Adenostemmatis of heat-clearing and toxic substances removing, ease pain the Rhizoma Angiopteridis Fokiensis of calming the nerves, the Radix Curcumae of heart fire-clearing upset-relieving, the Flos Aglaiae Odoratae of the dissipating blood stasis that dispels the wind, the Strobilus Abietis Fargesii of regulating menstruation and activating blood, multiple medical material synergism, plays effect of vital energy regualting and blood circulation-promoting, mind tranquilizing and the heart calming altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. for curing a demented preparation, it is characterized in that, being prepared from primarily of following bulk drugs, be mass parts: Stigma Maydis 10-16; Radix Chimonanthi praecocis 7-13; Exocarpium Citri Grandis 9-12; Flos Lilii viriduli 11-16; Concha Margaritifera 7-14; Radix Brassicae rapae 8-13; Herba Vernoniae Cinereae 10-14; Fail clothing 7-12; Radix grewiae bilobae 9-14; Rhizoma Anemones Altaicae 6-12; Herba Adenostemmatis 9-15; Rhizoma Angiopteridis Fokiensis 7-11; Radix Curcumae 10-15; Flos Aglaiae Odoratae 6-13; Strobilus Abietis Fargesii 8-12.
2. a kind ofly as claimed in claim 1 to it is characterized in that for curing demented preparation, Stigma Maydis 12-14; Radix Chimonanthi praecocis 9-11; Exocarpium Citri Grandis 10-11; Flos Lilii viriduli 12-15; Concha Margaritifera 9-12; Radix Brassicae rapae 10-11; Herba Vernoniae Cinereae 11-13; Fail clothing 9-10; Radix grewiae bilobae 10-13; Rhizoma Anemones Altaicae 8-10; Herba Adenostemmatis 11-13; Rhizoma Angiopteridis Fokiensis 8-10; Radix Curcumae 11-14; Flos Aglaiae Odoratae 8-11; Strobilus Abietis Fargesii 9-11(is preferably: Stigma Maydis 13; Radix Chimonanthi praecocis 10; Exocarpium Citri Grandis 10.5; Flos Lilii viriduli 13.5; Concha Margaritifera 10.5; Radix Brassicae rapae 10.5; Herba Vernoniae Cinereae 12; To fail clothing 9.5; Radix grewiae bilobae 11.5; Rhizoma Anemones Altaicae 9; Herba Adenostemmatis 12; Rhizoma Angiopteridis Fokiensis 9; Radix Curcumae 12.5; Flos Aglaiae Odoratae 9.5; Strobilus Abietis Fargesii 10).
3. a kind of as described in as arbitrary in claim 1-2 is characterized in that for curing demented preparation, and be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse steam 14-22 minute (preferred: to add mulse and steam 16-20 minute; Be more preferably: add mulse and steam 18 minutes), take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 10-20 minute (preferably: intense fire forges 12-18 minute; Be more preferably: intense fire forges 15 minutes), take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, decoct with water together with Radix grewiae bilobae to boiling with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 15-25 minute (preferred: to continue 18-22 minute; Be more preferably: continue 20 minutes), after filtration, collect filtrate;
(5) pulverized by made to step (1) (2) (3) crude drug, be added in step (4) gained filtrate, big fire is boiled to boiling, Guan Huohou, leaves standstill 5 minutes, filters, and collects filtrate, obtains decoction.
4. a kind of preparation method for curing demented preparation decoction as claimed in claim 3, is characterized in that, the 7-9 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 7.5-8.5 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 8 times of boiled crude drug quality).
5. a kind of as described in as arbitrary in claim 1-2 is characterized in that for curing demented preparation, and be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse steam 14-22 minute (preferred: to add mulse and steam 16-20 minute; Be more preferably: add mulse and steam 18 minutes), take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 10-20 minute (preferably: intense fire forges 12-18 minute; Be more preferably: intense fire forges 15 minutes), take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, add the soak by water of boiled crude drug quality 7 times to seethe with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 15-25 minute (preferred: lasting 18-22 minute; Be more preferably: continue 20 minutes), after filtration, collect filtrate;
(5) will be pulverized by step (1) (2) (3) made raw material, mix with step (4) gained filtrate, heating is concentrated into clear paste, adds adjuvant refined honey, stirs, obtain unguentum.
6. a kind of preparation method for curing demented preparation unguentum as claimed in claim 5, it is characterized in that, the amount that step (5) adds adjuvant refined honey is the 0.3-0.5 of clear paste quality doubly (preferred: the amount adding adjuvant refined honey is 0.4 times of clear paste quality).
7. a kind of as described in as arbitrary in claim 1-2 is characterized in that for curing demented preparation, and be made into pharmaceutically acceptable electuary, its preparation method is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse steam 14-22 minute (preferred: to add mulse and steam 16-20 minute; Be more preferably: add mulse and steam 18 minutes), take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 10-20 minute (preferably: intense fire forges 12-18 minute; Be more preferably: intense fire forges 15 minutes), take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, add the soak by water of boiled crude drug quality 7 times to seethe with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 15-25 minute (preferred: lasting 18-22 minute; Be more preferably: continue 20 minutes), after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverizes and sieves dry thing, makes medicated powder, obtain electuary together with step (1) (2) (3) made crude drug.
8. a kind of preparation method for curing demented preparation electuary as claimed in claim 7, is characterized in that, it is (preferred: to pulverize 160-200 mesh sieve that step (5) pulverized 120-240 mesh sieve; Be more preferably: pulverized 180 mesh sieves).
9. a kind of as described in as arbitrary in claim 1-2 is characterized in that for curing demented preparation, and be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Herba Vernoniae Cinereae, clothing of failing, Herba Adenostemmatis and Flos Aglaiae Odoratae clean remove impurity, be placed in steamer, add mulse steam 14-22 minute (preferred: to add mulse and steam 16-20 minute; Be more preferably: add mulse and steam 18 minutes), take out, slow fire is fried to dry, and taking-up cools;
(2) get Exocarpium Citri Grandis and Strobilus Abietis Fargesii removing impurity, be placed in marmite, add vinegar water mixed liquid (mass ratio of vinegar and water is 1:5) and do not have crude drug 3cm, moderate heat boils and is sucked to mixed liquor, and take out, slow fire is fried to dry, pulverizes;
(3) cleaned by Concha Margaritifera, be placed in refractory container, intense fire forges 10-20 minute (preferably: intense fire forges 12-18 minute; Be more preferably: intense fire forges 15 minutes), take out and put into mortar, water flies into fine powder, takes out;
(4) Radix Chimonanthi praecocis, Radix Brassicae rapae, Rhizoma Anemones Altaicae, Rhizoma Angiopteridis Fokiensis and Radix Curcumae are cleaned section, add ginger slice mixing, slow fire is fried to surperficial zoom, take out removing ginger slice, add the soak by water of boiled crude drug quality 7 times to seethe with excitement together with Radix grewiae bilobae with the Stigma Maydis of roguing, Flos Lilii viriduli, continue 15-25 minute (preferred: lasting 18-22 minute; Be more preferably: continue 20 minutes), after filtration, collect filtrate;
(5) spray drying step (4) gained filtrate, pulverized 80-140 mesh sieve (preferred: to pulverize 100-120 mesh sieve together with step (1) (2) (3) made crude drug by dry thing; Be more preferably: pulverized 110 mesh sieves), gained medicated powder is packed in capsule, obtains capsule.
10. a kind of preparation method for curing demented preparation capsule as claimed in claim 9, is characterized in that, in the every capsules of step (5), contained medicated powder weight is that 0.3-0.5g(is preferred: in every capsules, contained medicated powder weight is 0.4g).
CN201510611708.5A 2015-09-24 2015-09-24 Preparation for treating daftness and preparation method of preparation Pending CN105126028A (en)

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