CN105233034A - Liver-fire-clearing and bile-flow-promoting preparation for treating tinnitus and preparation method of liver-fire-clearing and bile-flow-promoting preparation - Google Patents
Liver-fire-clearing and bile-flow-promoting preparation for treating tinnitus and preparation method of liver-fire-clearing and bile-flow-promoting preparation Download PDFInfo
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Abstract
The invention discloses a liver-fire-clearing and bile-flow-promoting preparation for treating tinnitus. The liver-fire-clearing and bile-flow-promoting preparation is mainly prepared from the following active pharmaceutical ingredients in parts by weight: 8-14 parts of bamboo shavings, 10-16 parts of corn stigma, 7-13 parts of citronella, 9-14 parts of scutellaria indica, 8-13 parts of franchet peashrub, 7-14 parts of loranthus parasiticus, 9-15 parts of herb of white clover, 8-12 parts of hollyhock flowers, 9-13 parts of root of sandhill tylophora, 10-14 parts of arundina graminifolia, 8-15 parts of radix puerariae, 6-14 parts of fleshfingered citron flowers, 7-11 parts of apocynum venetum, and 6-12 parts of murraya paniculata. The liver-fire-clearing and bile-flow-promoting preparation is prepared through summary on many years of clinical practices, has the efficacies of clearing liver fire and promoting bile flow, and tonifying Qi and kidney, and is significant in curative effect.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the liver heat removing gallbladder-benefiting formulation and preparation method for the treatment of tinnitus.
Background technology
Tinnitus is that conscious in ear or intracranial have the sound, but the external world there is no corresponding sound source.Tinnitus majority is a kind of subjective symptom, is also usually hint or the warning of early stage hearing impairment.Tinnitus can of short duration or persistence exist. and mild tinnitus patient Shang Ke stands, but also can impact live and work, and severe tinnitus then can allow patient's malaise, and night is unable to fall asleep, has a strong impact on work and life.Chinese medicine is thought, tinnitus mostly is rage, terrified, liver and gall wind-fire superinverse, so that caused by the gas-tight resistance of shaoyang channel.Its clinical manifestation is totally said in multiformity, can one-sided or bilateral, also can be head ring, and sustainability existence also can intermittently occur, sound can be various, and tone is not just etc.
Publication No. CN104288694A(application number 201410566875.8) Chinese patent literature disclose a kind of Chinese medicine for the treatment of tinnitus, composed of the following components: Rhizoma Atractylodis Macrocephalae (parched), Pericarpium Citri Reticulatae, Poria, Radix Salviae Miltiorrhizae processed, Aspongopus, Radix Trichosanthis, the Radix Aucklandiae, Herba Salviae Chinensis, Radix Angelicae Sinensis, Semen Coicis, Rhizoma Curcumae, Herba Taraxaci, Rhizoma Imperatae, Spica Prunellae, to process Os Sepiae.Publication No. CN103463218A(application number 201310447054.8) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of tinnitus, belong to the field of Chinese medicines; The raw material of Chinese medicine preparation effective ingredient of the present invention consists of: Mytilus, Radix Crepidis elongatae, Folium Ilicis, Radix Arctii, Herba Crotalariae Ferrugineae, Herba Abutili, Concha Margaritifera, Herba Sarcopyramis nepalensis, Flos Caraganae Sinicae, Herba Ecliptae, Martianus dermestoides Chevr., Nigella damascena L., flower of Radix Notoginseng, Fructus Mori, Semen Cuscutae and Spica Prunellae.Publication No. CN102836347A(application number 201210346072.2) Chinese patent literature disclose a kind of Chinese medicine for the treatment of tinnitus, it is characterized in that the Chinese medicine preparation be made up of the medical material of following weight proportion: Radix Ginseng 10-12 part, Radix Ophiopogonis 10-15 part, Semen Armeniacae Amarum (parched) 10-12 part, Radix Salviae Miltiorrhizae 25-30 part, Fructus Corni 20-25 part, Radix Rehmanniae Preparata 20-30 part, Fructus Lycii 15-20 part, Radix Paeoniae Rubra 15-20 part, Cortex Moutan 10-12 part, Semen Persicae 10-15 part, Flos Carthami 10-12 part, Periostracum Cicadae 5-8 part, Flos Chrysanthemi 10-15 part, Rhizoma Gastrodiae 10-12 part, Poria 20-25 part, Rhizoma Atractylodis Macrocephalae 10-12 part, Herba Asari 3-5 part, Radix Bupleuri 10-12 part, Radix Angelicae Sinensis 10-12 part, Radix Paeoniae Alba 20-25 part.
Causing the reason of tinnitus has many, and some drugs mostly can only relief of symptoms, and long-term taking effect not significantly and damage health, therefore needs to study a kind of new Chinese medicine formula, can safe and effective treatment tinnitus.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take liver heat removing gallbladder-benefiting formulation and the preparation method of the wide treatment tinnitus of safe and applicable.
Technical scheme of the present invention is:
The liver heat removing gallbladder-benefiting formulation for the treatment of tinnitus, is prepared from primarily of following bulk drugs, is mass parts: Caulis Bambusae In Taenia 8-14; Stigma Maydis 10-16; Herba Cymbopogonis Citrari 7-13; Herba Scutellariae indicae 9-14; Flos Caraganae Franchetianae 8-13; Herba Taxilli 7-14; Herba Trifolii Pepentis 9-15; Flos althaeae roseae 8-12; Radix Tylophorae arenicolae 9-13; Herba Murdanniae Divergentis 10-14; Radix Puerariae 8-15; Flos Citri Sarcodactylis 6-14; Herba Apocyni veneti 7-11; Folium Et Cacumen Murrayae 6-12.
Preferred version is, Caulis Bambusae In Taenia 10-12; Stigma Maydis 12-14; Herba Cymbopogonis Citrari 9-11; Herba Scutellariae indicae 10-13; Flos Caraganae Franchetianae 10-11; Herba Taxilli 9-12; Herba Trifolii Pepentis 11-13; Flos althaeae roseae 9-11; Radix Tylophorae arenicolae 10-12; Herba Murdanniae Divergentis 11-13; Radix Puerariae 10-13; Flos Citri Sarcodactylis 8-12; Herba Apocyni veneti 8-10; Folium Et Cacumen Murrayae 8-10.
More preferably, Caulis Bambusae In Taenia 11; Stigma Maydis 13; Herba Cymbopogonis Citrari 10; Herba Scutellariae indicae 11.5; Flos Caraganae Franchetianae 10.5; Herba Taxilli 10.5; Herba Trifolii Pepentis 12; Flos althaeae roseae 10; Radix Tylophorae arenicolae 11; Herba Murdanniae Divergentis 12; Radix Puerariae 11.5; Flos Citri Sarcodactylis 10; Herba Apocyni veneti 9; Folium Et Cacumen Murrayae 9.
The preparation method of described preparation soft extract, step is as follows:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, smash to pieces and add crude drug quality 0.2-0.4 yellow wine doubly and mix thoroughly (preferred: the yellow wine adding crude drug quality 0.3 times is mixed thoroughly), slow fire stir-fries to being charred taste effusion, take out, cool;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 12-26 minute (preferred: Steam by water bath 16-22 minute; Be more preferably: Steam by water bath 19 minutes), take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 10-20 minute (preferably: soak 12-18 minute; Be more preferably: soak 15 minutes), take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire, pulverizes;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add boiled crude drug quality 5-8 water doubly (preferably: add boiled crude drug quality 6-7 water doubly; Be more preferably: the water adding boiled crude drug quality 6.5 times), moderate heat is heated to boiling, adds step (2) gained crude drug, turns little fire and decocts, collecting by filtration filtrate;
(5) mixed with step (4) gained filtrate by step (3) gained medicated powder, heating is concentrated into thick paste, obtains soft extract.
The preparation method of described preparation soft extract, step (4) turns little fire and decocts 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes).
The preparation method of described preparation pill, step is as follows:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, smash to pieces and add crude drug quality 0.2-0.4 yellow wine doubly and mix thoroughly (preferred: the yellow wine adding crude drug quality 0.3 times is mixed thoroughly), slow fire stir-fries to being charred taste effusion, take out, cool;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 12-26 minute (preferred: Steam by water bath 16-22 minute; Be more preferably: Steam by water bath 19 minutes), take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 10-20 minute (preferably: soak 12-18 minute; Be more preferably: soak 15 minutes), take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add boiled crude drug quality 5-8 water doubly (preferably: add boiled crude drug quality 6-7 water doubly; Be more preferably: the water adding boiled crude drug quality 6.5 times), moderate heat is heated to boiling, and turn little fire and decoct 20 minutes, collecting by filtration filtrate, heating is concentrated into clear paste;
(5) pulverized and sieved by step (2) (3) made crude drug, mix, make soft material, rubbing pill with step (4) gained clear paste, segmentation round, dry packing, makes pill.
The preparation method of described preparation pill, it is (preferred: to pulverize 100-120 mesh sieve that step (5) pulverized 80-140 mesh sieve; Be more preferably: pulverized 110 mesh sieves).
The preparation method of described preparation powder, step is as follows:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, smash to pieces and add crude drug quality 0.2-0.4 yellow wine doubly and mix thoroughly (preferred: the yellow wine adding crude drug quality 0.3 times is mixed thoroughly), slow fire stir-fries to being charred taste effusion, take out, cool;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 12-26 minute (preferred: Steam by water bath 16-22 minute; Be more preferably: Steam by water bath 19 minutes), take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 10-20 minute (preferably: soak 12-18 minute; Be more preferably: soak 15 minutes), take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add boiled crude drug quality 5-8 water doubly (preferably: add boiled crude drug quality 6-7 water doubly; Be more preferably: the water adding boiled crude drug quality 6.5 times), moderate heat is heated to boiling, adds step (2) (3) gained crude drug, and turn little fire and decoct 20 minutes, collecting by filtration filtrate, heating is concentrated into clear paste;
(5) lyophilization step (4) gained clear paste, pulverized 120-160 mesh sieve (preferred: to pulverize 130-150 mesh sieve; Be more preferably: pulverized 140 mesh sieves), make medicated powder, add cane sugar powder mixing, make powder.
The preparation method of described preparation powder, the amount that step (5) adds cane sugar powder is that the 0.1-0.4 of medicated powder quality is doubly (preferred: the amount adding cane sugar powder is 0.2-0.3 times of medicated powder quality; Be more preferably: the amount adding cane sugar powder is 0.25 times of medicated powder quality).
The preparation method of described preparation decoction, step is as follows:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, smash to pieces and add crude drug quality 0.2-0.4 yellow wine doubly and mix thoroughly (preferred: the yellow wine adding crude drug quality 0.3 times is mixed thoroughly), slow fire stir-fries to being charred taste effusion, take out, cool;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 12-26 minute (preferred: Steam by water bath 16-22 minute; Be more preferably: Steam by water bath 19 minutes), take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 10-20 minute (preferably: soak 12-18 minute; Be more preferably: soak 15 minutes), take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire, pulverizes;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, decoct with water, moderate heat is heated to boiling, adds step (2) gained crude drug, turns little fire and decocts 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes), collecting by filtration filtrate;
(5) by step (3) (4) made medicated powder and filtrate mixing, big fire is boiled to boiling, filters and collects filtrate, obtaining decoction.
The preparation method of described preparation decoction, step (4) amount of water is that the 6-9 of total raw material medicine quality is doubly (preferred: amount of water is 7-8 times of total raw material medicine quality; Be more preferably: amount of water is 7.5 times of total raw material medicine quality).
The liver heat removing gallbladder-benefiting formulation scientific formulation for the treatment of tinnitus provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, instant effect;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of liver heat removing function of gallbladder promoting, QI invigorating kidney tonifying;
3, Chinese crude drug selected by the present invention, wide material sources, cheap, do not increase patient economy burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Caulis Bambusae In Taenia: base is former: the intermediate layer that the stem stalk for grass family Phyllostachys plant phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle, the blue or green pole bamboo of Thorny Sinobambusa plant, Sinocalamus plant major part allusion quotation bamboo etc. goes crust to scrape.The property of medicine: sweet, is slightly cold.Return spleen, stomach, gallbladder meridian.Function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting, safe and sound removing heat from blood.Cure mainly cough due to lung-heat, dysphoria with smothery sensation is palpitated with fear, and gastric heat is vomitted oh, pregnancy reactions, frequent fetal movement, spits blood, epistaxis, hematuria, metrorrhagia.
Stigma Maydis: base is former: be the zeistic style of grass and stigma.Nature and flavor: sweet in the mouth; Light; Property is put down.Gui Jing: kidney; Stomach; Liver; Gallbladder meridian.Function cures mainly: inducing diuresis to remove edema; Liver heat removing function of gallbladder promoting.Main edema; Dribbling urination; Jaundice; Cholecystitis; Cholelithiasis; Hypertension; Diabetes; Galactostasis.
Herba Cymbopogonis Citrari: base is former: be the herb of grass Herba Cymbopogonis Citrari.Nature and flavor: pungent; Temperature; Sweet.Function cures mainly: dispelling wind and removing obstruction in the collateral; Warming middle-JIAO to relieve pain; Antidiarrheal.Main flu head-body-pain; Anemofrigid-damp arthralgia; Coldness and pain in the epigastrium; Have loose bowels; Traumatic injury.
Herba Scutellariae indicae: base is former: be the whole herb with root of labiate Herba Scutellariae indicae.Chemical analysis: herb is containing flavonoid, phenolic constituent, aminoacid, organic acid such as baicalins.Nature and flavor: arduous are flat.Gui Jing: " Quanzhou book on Chinese herbal medicine ": " enter the heart, liver, lung three warp." function cures mainly: dispel the wind, and invigorates blood circulation, removing toxic substances, pain relieving.Control traumatic injury, spit blood, hemoptysis, carbuncle, furunculosis, acute throat trouble, toothache.
Flos Caraganae Franchetianae: base is former: be the flower of leguminous plant Yunnan caragana.Nature and flavor: sweet micro-hardship; Flat.Gui Jing: kidney channel.Function cures mainly: QI invigorating kidney tonifying.Main tinnitus due to deficiency of the kidney, dizziness and blurred vision, headache, pulmonary tuberculosis cough, infantile malnutrition.
Herba Taxilli: base is former: be the branch and leaf of Loranthaceae plant Herba Visci, Herba Taxilli or loranthus yadoriki etc.Chemical analysis: Herba Visci stem, leaf are containing oleanolic acid, and β-Amyrin, meso inositol, flavone compound, still isolates Lupeol, cupreol and a flavonoid glycoside.Nature and flavor: bitter sweet are flat.Gui Jing: enter liver, kidney channel.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, and the meridian dredging, beneficial blood, antiabortive.Control soreness of waist and knee joint, muscles and bones flaccidity is weak, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.
Herba Trifolii Pepentis: base is former: be the herb of leguminous plant T.repens.Nature and flavor: taste is micro-sweet; Property is put down.Gui Jing: the heart; Spleen channel.Function cures mainly: heat clearing away; Removing heat from blood; Mind calming.Main insane disease; Bleeding hemorrhoids; Node is fast.
Flos althaeae roseae: base is former: be the flower of Malvaceae plant Althaea rosea (L.) Cavan..Nature and flavor: sweet; Salty; Cool.Gui Jing: lung; Large intestine; Urinary bladder channel.Function cures mainly: stop blooding with blood; Detoxicating and resolving stagnation of pathogens.Main haematemesis; Epistaxis; Have through too much; Leucorrhea with red and white discharge; Constipation and anuresis; Rubella in children; Malaria; Carbuncle furuncle and phyma; Wasp and scorpion sting; Scald; Burn.
Radix Tylophorae arenicolae: base is former: the root disappeared for the spirit of asclepiadaceae Cynanchum plant bamboo or aerial parts.The property of medicine: bitter, micro-pungent, flat.Return lung meridian.Function cures mainly: clearing away heat and cooling blood, and function of gallbladder promoting detoxifies.Cure mainly fever due to yin deficiency, asthenia chronic cough, spitting of blood, distending pain over the hypochondrium, vomiting, dysentery, puerperal fidgets due to deficiency, innominate toxic swelling, snakeworm, mad dog are bitten.
Herba Murdanniae Divergentis: base is former: be root or the Herb of Commelianaceae plant purple back of the body Herba Pyrolae.Nature and flavor: sweet; Micro-hardship; Flat.Function cures mainly: clearing away lung-heat to relieve cough; Invigorating the lung and the kidney; Regulating menstruation, hemostasis.Main cough due to lung-heat; The deficiency of vital energy is breathed with cough; Dizziness and tinnitus; Fracture; Spit blood.
Radix Puerariae: nature and flavor: sweet, pungent, cool.Gui Jing: return spleen, stomach warp.Effect: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Cure mainly: for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Flos Citri Sarcodactylis: base is former: be flower and the alabastrum of rutaceae Fructus Citri Sarcodactylis.Nature and flavor: micro-hardship; Tepor.Gui Jing: liver; Stomach warp.Function cures mainly: depressed liver-energy dispersing and QI regulating; Stomach function regulating soon every.Main stomachache due to hyperactive liver-QI attacking the stomach; Inappetence.
Herba Apocyni veneti: base is former: be the leaf of Apocynaceae Apocynum plant Herba Apocyni veneti.Composition: leaf contains Quercetin, isoquercitrin, hyperin, Trifolin, cloud English glycosides, rutin, cianidanol, anthraquinone, and the several amino acids such as glutamic acid, alanine.The property of medicine: sweet, micro-hardship, cool.Function cures mainly: heat clearing away, and suppressing the hyperactive liver is calmed the nerves, diuretic.Cure mainly hypertension, dizzy, headache, cardiopalmus, insomnia, edema oliguria.
Folium Et Cacumen Murrayae: base is former: be the stem and leaf of rutaceae Folium Et Cacumen Murrayae and Murraya microphylla.Nature and flavor: acrid in the mouth; Micro-hardship; Warm in nature; Mild toxicity.Gui Jing: the heart; Liver; Lung meridian.Function cures mainly: promoting flow of QI and blood; Eliminating stasis to stop pain; Removing toxic substances and promoting subsidence of swelling.Main gastralgia; Tumbling and swelling; Carbuncle sore; Snake bite and insect sting.
embodiment 1the liver heat removing gallbladder-benefiting formulation for the treatment of tinnitus, is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Bambusae In Taenia 8 parts, Stigma Maydis 10 parts, 7 parts, Herba Cymbopogonis Citrari, Herba Scutellariae indicae 9 parts, Flos Caraganae Franchetianae 8 parts, Herba Taxilli 7 parts, Herba Trifolii Pepentis 9 parts, Flos althaeae roseae 8 parts, Radix Tylophorae arenicolae 9 parts, Herba Murdanniae Divergentis 10 parts, Radix Puerariae 8 parts, Flos Citri Sarcodactylis 6 parts, Herba Apocyni veneti 7 parts, Folium Et Cacumen Murrayae 6 parts.The preparation method of the liver heat removing gallbladder-benefiting formulation soft extract of above-mentioned treatment tinnitus is:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, to smash to pieces and the yellow wine adding crude drug quality 0.3 times is mixed thoroughly, slow fire stir-fries to being charred taste effusion, takes out, cools;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 19 minutes, take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 15 minutes, take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire, pulverizes;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add the water of boiled crude drug quality 6.5 times, moderate heat is heated to boiling, adds step (2) gained crude drug, turns little fire and decocts 22 minutes, collecting by filtration filtrate;
(5) mixed with step (4) gained filtrate by step (3) gained medicated powder, heating is concentrated into thick paste, obtains soft extract.
embodiment 2the liver heat removing gallbladder-benefiting formulation for the treatment of tinnitus, is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Bambusae In Taenia 14 parts, Stigma Maydis 16 parts, 13 parts, Herba Cymbopogonis Citrari, Herba Scutellariae indicae 14 parts, Flos Caraganae Franchetianae 13 parts, Herba Taxilli 14 parts, Herba Trifolii Pepentis 15 parts, Flos althaeae roseae 12 parts, Radix Tylophorae arenicolae 13 parts, Herba Murdanniae Divergentis 14 parts, Radix Puerariae 15 parts, Flos Citri Sarcodactylis 14 parts, Herba Apocyni veneti 11 parts, Folium Et Cacumen Murrayae 12 parts.The preparation method of the liver heat removing gallbladder-benefiting formulation pill of above-mentioned treatment tinnitus is:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, to smash to pieces and the yellow wine adding crude drug quality 0.3 times is mixed thoroughly, slow fire stir-fries to being charred taste effusion, takes out, cools;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 19 minutes, take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 15 minutes, take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add the water of boiled crude drug quality 6.5 times, moderate heat is heated to boiling, and turn little fire and decoct 20 minutes, collecting by filtration filtrate, heating is concentrated into clear paste;
(5) step (2) (3) made crude drug was pulverized 110 mesh sieves, and mixed, make soft material, rubbing pill with step (4) gained clear paste, segmentation round, dry packing, makes pill.
Model case: xxx, male, 41 years old.Medical history: patient is telephone service person, receives calls for a long time, causes audition to decline to some extent, during recent rest, ear starts to occur drone the sound, and continue about 1 minute, attack times increases gradually, have a strong impact on work and life, to examination in hospital, be diagnosed as tinnitus.
Patient once took many medicines, and effect is not remarkable, and by the agency of takes this example gained pill, each 3-4 grain, warm boiled water, one day twice, within eight days, be a course for the treatment of, after patient takes five days, tinnitus symptom is alleviated to some extent, the mental status takes a turn for the better, after adhering to taking three courses for the treatment of, all diseases disappear entirely, and patient fully recovers, follow up a case by regular visits in 1 year, the state of an illness does not recur again.
embodiment 3the liver heat removing gallbladder-benefiting formulation for the treatment of tinnitus, is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Bambusae In Taenia 10 parts, Stigma Maydis 12 parts, 9 parts, Herba Cymbopogonis Citrari, Herba Scutellariae indicae 10 parts, Flos Caraganae Franchetianae 10 parts, Herba Taxilli 9 parts, Herba Trifolii Pepentis 11 parts, Flos althaeae roseae 9 parts, Radix Tylophorae arenicolae 10 parts, Herba Murdanniae Divergentis 11 parts, Radix Puerariae 10 parts, Flos Citri Sarcodactylis 8 parts, Herba Apocyni veneti 8 parts, Folium Et Cacumen Murrayae 8 parts.The preparation method of the liver heat removing gallbladder-benefiting formulation powder of above-mentioned treatment tinnitus is:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, to smash to pieces and the yellow wine adding crude drug quality 0.3 times is mixed thoroughly, slow fire stir-fries to being charred taste effusion, takes out, cools;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 19 minutes, take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 15 minutes, take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add the water of boiled crude drug quality 6.5 times, moderate heat is heated to boiling, adds step (2) (3) gained crude drug, turns little fire and decocts 20 minutes, collecting by filtration filtrate, heating is concentrated into clear paste;
(5) lyophilization step (4) gained clear paste, pulverized 140 mesh sieves, made medicated powder, added the cane sugar powder mixing of medicated powder quality 0.25 times, made powder.
Model case: xxx, women, 35 years old.Main suit: occur tinnitus without obvious inducement, have chirp, with spinning sensation; Medical history: patient, before three months, occurs tinnitus without obvious inducement, during beginning, symptom is comparatively light, and the persistent period is short, after increase the weight of gradually, and with dizzy, rotate depending on thing, audition declines to some extent, once arrives examination in hospital and takes medicine, and produces little effect.
Recommend to take this example gained powder, each 3-5g, warm boiled water through people, one day twice, within eight days, be a course for the treatment of, after patient takes a course for the treatment of, malaise symptoms obviously alleviates, adhere to taking two courses for the treatment of, tinnitus disappears, and continue to strengthen a course for the treatment of, patient's auditory rehabilitation is normal, follow up a case by regular visits to half a year, do not recur.
embodiment 4the liver heat removing gallbladder-benefiting formulation for the treatment of tinnitus, is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Bambusae In Taenia 12 parts, Stigma Maydis 14 parts, 11 parts, Herba Cymbopogonis Citrari, Herba Scutellariae indicae 13 parts, Flos Caraganae Franchetianae 11 parts, Herba Taxilli 12 parts, Herba Trifolii Pepentis 13 parts, Flos althaeae roseae 11 parts, Radix Tylophorae arenicolae 12 parts, Herba Murdanniae Divergentis 13 parts, Radix Puerariae 13 parts, Flos Citri Sarcodactylis 12 parts, Herba Apocyni veneti 10 parts, Folium Et Cacumen Murrayae 10 parts.The preparation method of the liver heat removing gallbladder-benefiting formulation decoction of above-mentioned treatment tinnitus is:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, to smash to pieces and the yellow wine adding crude drug quality 0.3 times is mixed thoroughly, slow fire stir-fries to being charred taste effusion, takes out, cools;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 19 minutes, take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 15 minutes, take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire, pulverizes;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add the soak by water of total raw material medicine quality 7.5 times, moderate heat is heated to boiling, adds step (2) gained crude drug, turns little fire and decocts 22 minutes, collecting by filtration filtrate;
(5) by step (3) (4) made medicated powder and filtrate mixing, big fire is boiled to boiling, filters and collects filtrate, obtaining decoction.
Model case: xxx, male, 59 years old.Medical history: patient occurs that tinnitus has three wheat harvesting periods, can hear buzz, in persistence, dizzy distending pain during outbreak, sensation of oppression over the chest with shortness of breath, mood is irritated, and anxiety, poor sleeping quality, has a strong impact on life, goes to see a doctor, and after taking medicine, effect is not remarkable.
Take this example gained decoction, each 200-250ml, warmly to take, one day twice eight days is a course for the treatment of, after patient takes a course for the treatment of, symptom starts to alleviate, adhere to taking three courses for the treatment of, tinnitus disappears substantially, and the mental status improves, consolidate a course for the treatment of, patient fully recovers, and uncomfortable disease is all eliminated, and follows up a case by regular visits to half a year without recurrence.
embodiment 5the liver heat removing gallbladder-benefiting formulation for the treatment of tinnitus, is prepared from (every part of 10g) primarily of following bulk drugs: Caulis Bambusae In Taenia 11 parts, Stigma Maydis 13 parts, 10 parts, Herba Cymbopogonis Citrari, Herba Scutellariae indicae 11.5 parts, Flos Caraganae Franchetianae 10.5 parts, Herba Taxilli 10.5 parts, Herba Trifolii Pepentis 12 parts, Flos althaeae roseae 10 parts, Radix Tylophorae arenicolae 11 parts, Herba Murdanniae Divergentis 12 parts, Radix Puerariae 11.5 parts, Flos Citri Sarcodactylis 10 parts, Herba Apocyni veneti 9 parts, Folium Et Cacumen Murrayae 9 parts.The preparation method of the liver heat removing gallbladder-benefiting formulation soft extract of above-mentioned treatment tinnitus is:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, to smash to pieces and the yellow wine adding crude drug quality 0.3 times is mixed thoroughly, slow fire stir-fries to being charred taste effusion, takes out, cools;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 19 minutes, take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 15 minutes, take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire, pulverizes;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add the water of boiled crude drug quality 6.5 times, moderate heat is heated to boiling, adds step (2) gained crude drug, turns little fire and decocts 22 minutes, collecting by filtration filtrate;
(5) mixed with step (4) gained filtrate by step (3) gained medicated powder, heating is concentrated into thick paste, obtains soft extract.
test example 1the clinical practice of the liver heat removing gallbladder-benefiting formulation (embodiment 5) of gained treatment tinnitus of the present invention:
Choose crowd: in April ,-2015 in June, 2014, according to medical case history, four hospital's Screening Diagnosis patient 316 example, age 18-70 year, 42.6 ± 1.8 years old mean age, the course of disease 1 month-15 months, wherein male patient 163 example, female patient 153 example, all gets rid of the tinnitus that external ear and middle ear cause in screening, anemia of pregnant woman, pregnancy women and women breast-feeding their children, actute infection person, merge the patient of brain tumor and malignant tumor.
Before test, patient is divided into two groups at random, experimental group 200 example and matched group 116 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 6-10g, one day twice, warm boiled water, within eight days, is a course for the treatment of; Matched group takes other conventional medicines (Shu Erdan, LIUWEI DIHUANG WAN, Ginaton etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: tinnitus disappears, and simultaneous phenomenon is all eliminated, and follows up a case by regular visits in one month without recurrence; (2) effective: tinnitus situation reduces more than 2 ranks (comprising 2 ranks), and simultaneous phenomenon is alleviated to some extent; (3) effective: tinnitus situation reduces by 1 rank; (4) invalid: tinnitus classification is without any change.Total effective rate=cure rate+obvious effective rate+effective percentage
Clinical effectiveness: after the taking medicine of three courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
The total effective rate of experimental group is 98.5%, and the total effective rate of matched group is 81.1%, is starkly lower than the therapeutic effect of experimental group, illustrates that products obtained therefrom of the present invention is evident in efficacy, and cure rate is high.
The Chinese medicine used in the present invention, Caulis Bambusae In Taenia removing heat-phlegm, Stigma Maydis liver heat removing function of gallbladder promoting, Herba Cymbopogonis Citrari dispelling wind and removing obstruction in the collateral, Herba Scutellariae indicae expelling wind and activating blood circulation, Flos Caraganae Franchetianae QI invigorating kidney tonifying, Herba Taxilli stimulates the menstrual flow and enriches blood, Herba Trifolii Pepentis clearing away heat and cooling blood, Flos althaeae roseae detoxicating and resolving stagnation of pathogens, Radix Tylophorae arenicolae function of gallbladder promoting detoxifies, Herba Murdanniae Divergentis invigorating the lung and the kidney, Radix Puerariae expelling pathogenic factors from muscles for reducing heat, Flos Citri Sarcodactylis depressed liver-energy dispersing and QI regulating, Herba Apocyni veneti heat clearing away suppressing the hyperactive liver, Folium Et Cacumen Murrayae promoting flow of QI and blood, multiple medical material synergism, plays effect of liver heat removing function of gallbladder promoting, QI invigorating kidney tonifying altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the liver heat removing gallbladder-benefiting formulation of tinnitus, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Caulis Bambusae In Taenia 8-14; Stigma Maydis 10-16; Herba Cymbopogonis Citrari 7-13; Herba Scutellariae indicae 9-14; Flos Caraganae Franchetianae 8-13; Herba Taxilli 7-14; Herba Trifolii Pepentis 9-15; Flos althaeae roseae 8-12; Radix Tylophorae arenicolae 9-13; Herba Murdanniae Divergentis 10-14; Radix Puerariae 8-15; Flos Citri Sarcodactylis 6-14; Herba Apocyni veneti 7-11; Folium Et Cacumen Murrayae 6-12.
2. the liver heat removing gallbladder-benefiting formulation for the treatment of tinnitus as claimed in claim 1, is characterized in that, Caulis Bambusae In Taenia 10-12; Stigma Maydis 12-14; Herba Cymbopogonis Citrari 9-11; Herba Scutellariae indicae 10-13; Flos Caraganae Franchetianae 10-11; Herba Taxilli 9-12; Herba Trifolii Pepentis 11-13; Flos althaeae roseae 9-11; Radix Tylophorae arenicolae 10-12; Herba Murdanniae Divergentis 11-13; Radix Puerariae 10-13; Flos Citri Sarcodactylis 8-12; Herba Apocyni veneti 8-10; Folium Et Cacumen Murrayae 8-10(is preferably: Caulis Bambusae In Taenia 11; Stigma Maydis 13; Herba Cymbopogonis Citrari 10; Herba Scutellariae indicae 11.5; Flos Caraganae Franchetianae 10.5; Herba Taxilli 10.5; Herba Trifolii Pepentis 12; Flos althaeae roseae 10; Radix Tylophorae arenicolae 11; Herba Murdanniae Divergentis 12; Radix Puerariae 11.5; Flos Citri Sarcodactylis 10; Herba Apocyni veneti 9; Folium Et Cacumen Murrayae 9).
3. the preparation method of the preparation soft extract as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, smash to pieces and add crude drug quality 0.2-0.4 yellow wine doubly and mix thoroughly (preferred: the yellow wine adding crude drug quality 0.3 times is mixed thoroughly), slow fire stir-fries to being charred taste effusion, take out, cool;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 12-26 minute (preferred: Steam by water bath 16-22 minute; Be more preferably: Steam by water bath 19 minutes), take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 10-20 minute (preferably: soak 12-18 minute; Be more preferably: soak 15 minutes), take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire, pulverizes;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add boiled crude drug quality 5-8 water doubly (preferably: add boiled crude drug quality 6-7 water doubly; Be more preferably: the water adding boiled crude drug quality 6.5 times), moderate heat is heated to boiling, adds step (2) gained crude drug, turns little fire and decocts, collecting by filtration filtrate;
(5) mixed with step (4) gained filtrate by step (3) gained medicated powder, heating is concentrated into thick paste, obtains soft extract.
4. the preparation method of preparation soft extract as claimed in claim 3, is characterized in that, step (4) turns little fire and decocts 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes).
5. the preparation method of the preparation pill as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, smash to pieces and add crude drug quality 0.2-0.4 yellow wine doubly and mix thoroughly (preferred: the yellow wine adding crude drug quality 0.3 times is mixed thoroughly), slow fire stir-fries to being charred taste effusion, take out, cool;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 12-26 minute (preferred: Steam by water bath 16-22 minute; Be more preferably: Steam by water bath 19 minutes), take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 10-20 minute (preferably: soak 12-18 minute; Be more preferably: soak 15 minutes), take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add boiled crude drug quality 5-8 water doubly (preferably: add boiled crude drug quality 6-7 water doubly; Be more preferably: the water adding boiled crude drug quality 6.5 times), moderate heat is heated to boiling, and turn little fire and decoct 20 minutes, collecting by filtration filtrate, heating is concentrated into clear paste;
(5) pulverized and sieved by step (2) (3) made crude drug, mix, make soft material, rubbing pill with step (4) gained clear paste, segmentation round, dry packing, makes pill.
6. the preparation method of preparation pill as claimed in claim 5, is characterized in that, it is (preferred: to pulverize 100-120 mesh sieve that step (5) pulverized 80-140 mesh sieve; Be more preferably: pulverized 110 mesh sieves).
7. the preparation method of the preparation powder as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, smash to pieces and add crude drug quality 0.2-0.4 yellow wine doubly and mix thoroughly (preferred: the yellow wine adding crude drug quality 0.3 times is mixed thoroughly), slow fire stir-fries to being charred taste effusion, take out, cool;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 12-26 minute (preferred: Steam by water bath 16-22 minute; Be more preferably: Steam by water bath 19 minutes), take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 10-20 minute (preferably: soak 12-18 minute; Be more preferably: soak 15 minutes), take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, add boiled crude drug quality 5-8 water doubly (preferably: add boiled crude drug quality 6-7 water doubly; Be more preferably: the water adding boiled crude drug quality 6.5 times), moderate heat is heated to boiling, adds step (2) (3) gained crude drug, and turn little fire and decoct 20 minutes, collecting by filtration filtrate, heating is concentrated into clear paste;
(5) lyophilization step (4) gained clear paste, pulverized 120-160 mesh sieve (preferred: to pulverize 130-150 mesh sieve; Be more preferably: pulverized 140 mesh sieves), make medicated powder, add cane sugar powder mixing, make powder.
8. the preparation method of preparation powder as claimed in claim 7, is characterized in that, the amount that step (5) adds cane sugar powder is that the 0.1-0.4 of medicated powder quality is doubly (preferred: the amount adding cane sugar powder is 0.2-0.3 times of medicated powder quality; Be more preferably: the amount adding cane sugar powder is 0.25 times of medicated powder quality).
9. the preparation method of the preparation decoction as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Stigma Maydis, Flos Caraganae Franchetianae, Flos althaeae roseae and Flos Citri Sarcodactylis and clean remove impurity, be placed in container, smash to pieces and add crude drug quality 0.2-0.4 yellow wine doubly and mix thoroughly (preferred: the yellow wine adding crude drug quality 0.3 times is mixed thoroughly), slow fire stir-fries to being charred taste effusion, take out, cool;
(2) Herba Taxilli, Herba Apocyni veneti and Folium Et Cacumen Murrayae are picked up decontamination, clean chopping, add the Semen Sesami mixing grinding to form end, be placed in steamer, Steam by water bath 12-26 minute (preferred: Steam by water bath 16-22 minute; Be more preferably: Steam by water bath 19 minutes), take out and mix with step (1) made crude drug;
(3) get Radix Tylophorae arenicolae, Herba Murdanniae Divergentis and Radix Puerariae remove impurity to clean, be placed in boiling water and soak 10-20 minute (preferably: soak 12-18 minute; Be more preferably: soak 15 minutes), take out section, mix thoroughly with refined honey, put into frying pan, taking-up in 8 minutes is fried in big fire, pulverizes;
(4) Caulis Bambusae In Taenia, Herba Cymbopogonis Citrari, Herba Scutellariae indicae and Herba Trifolii Pepentis roguing are cleaned, be placed in marmite, decoct with water, moderate heat is heated to boiling, adds step (2) gained crude drug, turns little fire and decocts 18-26 minute (preferably: turn little fire and decoct 20-24 minute; Be more preferably: turn little fire and decoct 22 minutes), collecting by filtration filtrate;
(5) by step (3) (4) made medicated powder and filtrate mixing, big fire is boiled to boiling, filters and collects filtrate, obtaining decoction.
10. the preparation method of preparation decoction as claimed in claim 9, is characterized in that, step (4) amount of water is that the 6-9 of total raw material medicine quality is doubly (preferred: amount of water is 7-8 times of total raw material medicine quality; Be more preferably: amount of water is 7.5 times of total raw material medicine quality).
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105616618A (en) * | 2016-04-01 | 2016-06-01 | 广西壮族自治区中医药研究院 | Application of murraya exotica in preparing cholagogue medicine |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104365942A (en) * | 2014-11-20 | 2015-02-25 | 青岛恒波仪器有限公司 | Liver clearing and vision improving mulberry healthy tea and preparation method thereof |
| CN104623232A (en) * | 2015-01-14 | 2015-05-20 | 姜丽莎 | Traditional Chinese medicine composition for treating tinnitus |
| CN104940562A (en) * | 2015-06-30 | 2015-09-30 | 吕超 | Traditional Chinese medicine composition for treating tinnitus |
-
2015
- 2015-10-23 CN CN201510692202.1A patent/CN105233034A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104365942A (en) * | 2014-11-20 | 2015-02-25 | 青岛恒波仪器有限公司 | Liver clearing and vision improving mulberry healthy tea and preparation method thereof |
| CN104623232A (en) * | 2015-01-14 | 2015-05-20 | 姜丽莎 | Traditional Chinese medicine composition for treating tinnitus |
| CN104940562A (en) * | 2015-06-30 | 2015-09-30 | 吕超 | Traditional Chinese medicine composition for treating tinnitus |
Non-Patent Citations (3)
| Title |
|---|
| 刘硕: "《美容养颜花卉饮品家庭制作》", 30 April 2004 * |
| 宁剑等: "中药葛根治疗耳鸣的机制探讨", 《浙江中西医结合杂志》 * |
| 王洁等: "耳鸣的中医药治疗进展", 《河北中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105616618A (en) * | 2016-04-01 | 2016-06-01 | 广西壮族自治区中医药研究院 | Application of murraya exotica in preparing cholagogue medicine |
| CN105616618B (en) * | 2016-04-01 | 2019-11-26 | 广西壮族自治区中医药研究院 | Purposes of the kamuning in terms of preparing Cholagogue drug |
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Application publication date: 20160113 |