CN104491531A - Traditional Chinese medicine granule for treating consumptive thirst caused by diabetes and preparation method of traditional Chinese medicine granule - Google Patents
Traditional Chinese medicine granule for treating consumptive thirst caused by diabetes and preparation method of traditional Chinese medicine granule Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine granule for treating the consumptive thirst caused by the diabetes. The traditional Chinese medicine granule for treating the consumptive thirst caused by the diabetes comprises the following raw materials in parts by weight: 3-9 parts of medical stone, 6-12 parts of willow herb, 12-25 parts of sticky rice, 8-16 parts of semen raphani, 6-12 parts of mulberry seeds, 5-15 parts of ligusticum wallichii, 3-7 parts of cowpea, 7-15 parts of fructus cannabis, 10-20 parts of rhizoma anemarrhenae, 3-9 parts of radix asparagi, 9-15 parts of semen cuscutae, 5-15 parts of eupatorium, 3-12 parts of water chestnut, 3-8 parts of bohadschia and 10-20 parts of angelica sinensis. The traditional Chinese medicine granule can be used for relieving symptoms of polydipsia and dieresis and can also be used for improving the symptoms of emaciation and fatigue caused by diabetes; meanwhile, the traditional Chinese medicine granule can be used for regulating blood glucose, and has the remarkable effect of treating the consumptive thirst caused by the diabetes. The traditional Chinese medicine granule is an ideal compound preparation which can be used for treating the consumptive thirst caused by the diabetes.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to Chinese medicine granules of the diabetes that a kind for the treatment of is caused by diabetes and preparation method thereof.
Background technology
Diabetes (diabetes) are the diseases of the easy overheap of glucose in a kind of blood, domestic to its symptom so-called " hyperglycemia ", together be called " three-hypers " with hypertension, hyperlipidemia, be by the various virulence factor such as inherited genetic factors, immunologic function disorder, infected by microbes and toxin thereof, free radical toxin, Nervous and Mental Factors act on body cause hypoinsulinism, insulin resistant etc. and cause a series of metabolism disorder syndrome such as sugar, protein, fat, water and eletrolytes.External its another name of giving is " silent killer ", and particularly " adult diabetes mellitus ", it is high especially that the middle age of more than 40 years old catches rate.
Diabetes divide the diabetes of type i diabetes, type ii diabetes, gestational diabetes and other specific types.1. I type patients with type Ⅰ DM is a kind of autoimmune disease.Autoimmune disease is because the immune system of health is attacked self making.The pancreas beta cell of immune system to self excreting insulin of diabetics is made and is attacked and kill them, and result pancreas can not secrete enough insulins.Because insulin secretion lacks, patient need rely on exogenous insulin and supplement to sustain life.
2. type ii diabetes is Adult Onset's patients with type Ⅰ DM, how the sequela of 35 ~ 40 years old, accounts for diabetics more than 90%.The ability producing insulin in patient body not completely loses, and in some patient bodies, insulin even produces too much, but the action effect of insulin is had a greatly reduced quality, and the insulin therefore in patient body is a kind of shortage relatively.3. gestational diabetes refers to the diabetes that women suffers from phenolics.Can there are diabetes at phenolics in the women of clinical data display nearly 2 ~ 3%, patient's diabetes after gestation disappear automatically.Gestational diabetes more easily occurs in obesity and lying-in woman advanced in years.Type ii diabetes may be developed into after having the gestational diabetes women of 30% nearly.The performances such as wherein type ii diabetes has very strong heritability and environmental factors, and in significant heterogeneous, and polyuria, polydipsia, polyphagia can appear in its model case, become thin, i.e. " three-many-one-little " symptom, namely so-called diabetes.
Diabetes is the name of disease of Chinese medicine, refer to polydipsia, polyuria, polyphagia and become thin, tired, urinate the sweet comprehensive disease for principal character.Also known as diseases due to endogenous heat of ZANG FU organs, diabetes involving in upper-JIAO, disappear.Diabetes pathological changes internal organs are at lung stomach kidney.Dryness-heat impairing the lung, then control joint dereliction of duty, lung is cloth Tianjin not; Scorchingly to injure one's stomach, then excessiveness of stomach-fire, rapid digestion of food and polyorexia; Scorchingly be impairment of the kidney, then kidney loses astringency inducing, precise and tiny bet.All eating and drinking without temperances, surfeit delicious food, or disorder of emotion, stagnated QI transforming into fire, or labor is for excessively, consumes the moon that is impairment of the kidney, all can bring out this disease.
With the passing of time, then easily there are following two kinds of pathological changes: one is deficiency of YIN affecting YANG, deficiency in both YIN and YANG in diabetes.Be this though quench one's thirst with the deficiency of YIN, scorching is mark, and due to interdependence between yin and yang, Yin grows while yang is generating, if the course of disease with the passing of time, deficiency of YIN affecting YANG, then cause deficiency in both YIN and YANG.Wherein with insufficiency of kidney-YANG and deficiency of spleen-YANG comparatively common.Two is disease people's networks for a long time, and the blood vessels stasis of blood is stagnant.The diabetes caused by diabetes is the disease of a kind of disease and multiple internal organs, affects the normal operation of QI and blood, and yin asthenia generating intrinsic heat, consumption impairment of body fluid liquid, also makes hematogenous blockage and the hyperamization arteries and veins stasis of blood is stagnant.Blood stasis is one of the important pathogenesis of the diabetes caused by diabetes, and the generation of the diabetes multiple complications caused by diabetes is also closely relevant with blood stasis.Diabetes often occurs together with diabetes, and some people even it can be used as the basis for estimation of diabetic disorders.
In the prescription of existing treatment diabetes, Authorization Notice No. CN 103127380 B(application number 201310038187.X) the compound preparation that patent discloses the diabetes that a kind for the treatment of is caused by diabetes, be prepared from by the crude drug of following weight proportioning: Radix Astragali 10-30 part, Radix Codonopsis 9-30 part, Radix Rehmanniae 12-30 part, Rhizoma Dioscoreae 15-30 part, Rhizoma Polygonati Odorati 6-12 part, Fructus Lycii 5-15 part, Radix Trichosanthis 6-15 part, Radix Puerariae 7-15 part, Fructus Momordicae charantiae powder 20-50 part, Radix Linderae 3-9 part, Fructus Mori 9-15 part, Cortex Lycii 15-30 part.Authorization Notice No. CN 102343026 B(application number 201110304420.5) patent discloses a kind of Chinese medicine composition for the treatment of diabetes, it is characterized in that, this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba Portulacae 20-45 part, Rhizoma Coptidis 1-8 part, Radix Scrophulariae 5-25 part, Radix Trichosanthis 20-45 part, Flos Lonicerae 5-25 part, Radix Puerariae 5-25
Part, Rhizoma Anemarrhenae 5-25 part, Radix Rehmanniae 5-25 part, Gypsum Fibrosum 5-25 part, Radix Codonopsis 5-25 part, Rhizoma Atractylodis Macrocephalae 5-25 part, Radix Astragali 5-25 part, Radix Rehmanniae Preparata 5-25 part, Fructus Corni 5-25 part, Rhizoma Dioscoreae 5-25 part.
As can be seen here, Chinese medicine goes good curative effect in treatment diabetes and the diabetes that caused by diabetes, but its preparation method all more complicated, great majority are decoctions, and as everyone knows, decoction is inconvenient to carry, and pure Chinese medicine decoction hardship very, be not easy to swallow.
Summary of the invention
For the deficiency of existing treatment diabetes method, an object of the present invention is the Chinese medicine granules of the diabetes providing a kind for the treatment of to be caused by diabetes, taking in this medicine therapeutic process, instant effect, and have no side effect, while improving polydipsia, polyuria symptom, can also regulate blood glucose, be the ideal Chinese medicine granule of the diabetes that a kind for the treatment of is caused by diabetes.
Another object of the present invention is just to provide the preparation method of the Chinese medicine granules of the diabetes that above-mentioned treatment is caused by diabetes.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicine granules for the diabetes caused by diabetes, each crude drug is as follows, is weight portion: Maifanitum 3-9, Herba Lythri Salicariae 6-12, Oryza glutinosa 12-25, Radix Raphani 8-16, Fructus Mori 6-12, Rhizoma Chuanxiong 5-15, Semen vignae sinensis 3-7, Fructus Cannabis 7-15, Rhizoma Anemarrhenae 10-20, Radix Asparagi 3-9, Semen Cuscutae 9-15, Herba Eupatorii 5-15, Corm Eleocharitis 3-12, Bai Nican 3-8, Radix Angelicae Sinensis 10-20.
Treat a Chinese medicine granules for the diabetes caused by diabetes, preferred scheme, each crude drug is as follows, be weight portion: Maifanitum 5-7, Herba Lythri Salicariae 8-10, Oryza glutinosa 16-21, Radix Raphani 12-14, Fructus Mori 8-10, Rhizoma Chuanxiong 8-13, Semen vignae sinensis 4-6, Fructus Cannabis 10-12, Rhizoma Anemarrhenae 13-18, Radix Asparagi 5-7, Semen Cuscutae 11-13, Herba Eupatorii 8-13, Corm Eleocharitis 5-10, Bai Nican 4-6, Radix Angelicae Sinensis 13-18.
Treat a Chinese medicine granules for the diabetes caused by diabetes, better preferred scheme, each crude drug is as follows, be weight portion: Maifanitum 6, Herba Lythri Salicariae 9, Oryza glutinosa 18, Radix Raphani 13, Fructus Mori 9, Rhizoma Chuanxiong 10, Semen vignae sinensis 5, Fructus Cannabis 11, the Rhizoma Anemarrhenae 15, Radix Asparagi 6, Semen Cuscutae 12, Herba Eupatorii 11, Corm Eleocharitis 8, Bai Nican 5, Radix Angelicae Sinensis 15.
Treat a preparation method for the Chinese medicine granules of the diabetes caused by diabetes, step is as follows:
1. Maifanitum is placed in the hot water of 80-100 DEG C, when water temperature is cooled to room temperature, adds Sal, after Sal melts completely, soak 10-30 minute (preferably 20 minutes), taking-up is placed on clean gauze stand-by;
2. get Radix Angelicae Sinensis and Rhizoma Chuanxiong to clean, drain away the water, high temperature sterilization 1-5 minute, section, uses rice vinegar uniform spraying, slightly vexed 10 minutes, puts in the hot pot that dryouies and fries 3-8 minute with low baking temperature, take out, and when placing room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Herba Lythri Salicariae, Fructus Mori, Fructus Cannabis, the Rhizoma Anemarrhenae, Radix Asparagi, Semen Cuscutae, Herba Eupatorii, Corm Eleocharitis and Bai Nican, little fire dries 10-30 minute slowly, dries in the air coolly to grind to form smalls, crosses 80-120 mesh sieve (preferably 100 mesh sieves);
4. cleaned by Radix Raphani, the block being cut into coin-size and the Semen vignae sinensis being cut into long 1-3 centimetre after cleaning mix stand-by;
5. Oryza glutinosa is eluriated 1-3 time, add Oryza glutinosa weight 8-12 water doubly, soak after 1 hour and add step 1. gained Maifanitum, big fire adds step 4. gains after boiling, after big fire boils 4-8 minute, be blended into cold water, turn slow fire boiling 20-40 minute, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Radix Raphani and Semen vignae sinensis, Maifanitum is taken out, adds step 2. and 3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste at 50-70 DEG C of dry 10-18 hour, make granule.
The preparation method of above-mentioned Chinese medicine granules, step 1. Maifanitum is placed in the hot water (preferred Maifanitum is placed in the hot water of 90 DEG C) of 85-95 DEG C.
The preparation method of above-mentioned Chinese medicine granules, step 2. high temperature sterilization 2-4 minute (preferred high temperature sterilization 3 minutes).
The preparation method of above-mentioned Chinese medicine granules, step 3. little fire is dried 15-25 minute (preferred little fire dries 20 minutes slowly) slowly.
The preparation method of above-mentioned Chinese medicine granules, 5. step adds Oryza glutinosa weight 9-11 water (preferably adding the water of Oryza glutinosa weight 10 times) doubly.
The preparation method of above-mentioned Chinese medicine granules, step after 5. big fire boils 5-7 minute, is blended into cold water, turns slow fire boiling 25-35 minute (preferred big fire boil 6 minutes after, be blended into cold water, turn slow fire boiling 30 minutes).
The preparation method of above-mentioned Chinese medicine granules, step 6. thick paste, at 55-65 DEG C of dry 12-16 hour, makes granule (preferred thick paste, 60 DEG C of dryings 14 hours, makes granule).
The present invention is to the Be very effective of the diabetes caused by diabetes, and be the therapeutic effect making the present invention reach best, every day 3 times, take respectively at half an hour after breakfast, lunch and dinner, each 2g, boiled water is taken after mixing it with water, and within 10 days, is a course for the treatment of.
The pharmacological effect of each crude drug is respectively:
Maifanitum: base is former: be Acid-intermediate igneous rock rocks beschtauite.Composition: Maifanitum main component has silicon dioxide, aluminium oxide, ferrum oxide, ferrous oxide, magnesium oxide, calcium oxide, sodium oxide, potassium oxide, titanium dioxide, phosphorus pentoxide, manganese oxide, carbon dioxide, and the trace element such as fluorine, sulfur, strontium, barium, copper, zinc.The property of medicine: " detailed outline ": " sweet, temperature, nontoxic." function cures mainly: removing toxic substances and promoting granulation, damp eliminating spleen invigorating.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.Generally make health product.
Herba Lythri Salicariae: have another name called Purple Loosestrife, Herba pteridis vittatae, to tooth grass, be the herb of Lythraceae Lythrum plant Herba Lythri Salicariae.The property of medicine: bitter in the mouth, cold in nature.Composition: herb contains Salicarin, choline, gallotannin, orientin, chlorogenic acid etc.Find according to modern pharmacological research, this medical instrument has blood sugar lowering, antibacterial, heat-clearing and toxic substances removing, anastaltic effect, and for hyperglycemia, spit blood, epistaxis, has loose bowels, and skin infection festers.
Oryza glutinosa: base is former: be the kernel that shells of grass family oryza plant Oryza sativa L. var. glutinosa Matsum..The property of medicine: sweet, temperature.Return spleen, stomach, lung meridian.Function cures mainly: invigorating the spleen and replenishing QI, invigorating the spleen to arrest diarrhea, reducing urination, arresting sweating, removing toxic substances.Cure mainly Deficiency and coldness of spleen and stomach to have loose bowels, cholera is told inverse, frequent micturition of quenching one's thirst, spontaneous perspiration, variola, hemorrhoid.
Radix Raphani: base is former: be fresh of Cruciferae Radix Raphani platymiscium Radix Raphani.Composition: root contains glycoside glucosinolate, glucose raphanin, raphanusin.Phenolic acids: P-coumaric acid, caffeic acid, ferulic acid, phenylpyruvic acid, gentisic acid etc.The property of medicine: acrid, sweet, cool; Ripe person is sweet, flat.Return spleen, stomach, lung, large intestine channel.Function cures mainly: help digestion, and the therapeutic method to keep the adverse QI flowing downwards is reduced phlegm, hemostasis.Cure mainly dyspepsia, food stagnation distension, acid regurgitation, regurgitation of food from the stomach, tells food, and hemorrhoidal hamorrhage is had loose bowels, dysentery, constipation, phlegm-heat cough, discomfort in the throat, hemoptysis, and spit blood, epistaxis, has blood in stool, and quenches one's thirst, and drenches worm.Outer treatment skin ulcer abscess, damage congestive edema, scalds and chilblain.
Fructus Mori: base is former: be the dry fruit ear of Moraceae Mulberry plant Mulberry.Composition: fruit ear is containing vitamin B1, B2 and carotene; The fatty acid of its lipid is mainly linoleic acid, oleic acid, palmitic acid, stearic acid, and there still have to be sad on a small quantity, n-nonanoic acid, capric acid etc.The property of medicine: sweet, sour, cold.Return sweet, kidney channel.Function cures mainly: nourishing YIN and benefiting blood, promotes the production of body fluid, intestine moistening.Cure mainly having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence, tinnitus, early whitening of beard and hair, insomnia, quenches one's thirst, the soreness of waist, dryness of the intestine constipation, tinea alba.
Rhizoma Chuanxiong: activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Semen vignae sinensis: base is former: be the seed of pulse family Vigna plant Semen vignae sinensis.Composition: containing aminoacid: cystine, aspartic acid, threonine, serine, glutamic acid, glycine, alanine, methionine etc.The property of medicine: sweet, salty, flat.Return spleen, kidney channel.Function cures mainly: invigorating spleen to remove dampness, the kidney invigorating arresting seminal emission.Cure mainly weakness of the spleen and stomach, vomiting and diarrhoea dysentery, lumbago due to renal deficiency, seminal emission, quenches one's thirst, leucorrhea nebulousurine, frequent micturition.
Fructus Cannabis: base is former: be the kernel of Moraceae Cannabis plant Fructus Cannabis.Composition: seed contains trigonelline, L-dextrorotation isoleucine Glycocoll betaine.Seed fatty acids and lipid: stearic acid, arachidic acid, lignoceric acid, Palmic acid, palmitoleic acid etc.The property of medicine: sweet, flat.Return spleen, stomach, large intestine channel.Function cures mainly: moisturize laxation, and diuretic is invigorated blood circulation.Cure mainly dryness of the intestine constipation, migratory arthralgia, quench one's thirst, edema due to wind pathogen, beriberi, pyretic stranguria, dysentery, menoxenia, skin ulcer tinea, erysipelas.
The Rhizoma Anemarrhenae: base is former: be the rhizome of the Liliaceae Anemarrhena plant Rhizoma Anemarrhenae.Composition: containing zhimusaponin A-I, A-II, A-III, A-IV in rhizome, B-I and B-II. wherein zhimusaponin A-I is Sa Ersa ruscogenin β-D-galactopyranosyl glucoside, and zhimusaponin A-III is the disaccharidase glycoside that Sa Ersa ruscogenin and timobiose are combined into. the ruscogenin in Asphodeloides Bge Rhizome has Sa Ersa ruscogenin, markogenin, new gitogenin etc.
The property of medicine: bitter, cold.Return lung, stomach, kidney channel.Function cures mainly: clearing away heat-fire, nourshing Yin and drynsessmoistening prescription.Cure mainly the high hot excessive thirst of epidemic febrile disease, cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia, quenches one's thirst.
Radix Asparagi: base is former: be the tuber of Liliaceae asparagus plant Radix Asparagi.Composition: tuber is containing steroidal saponin: Smilax saponin B is protodioscin, another containing 6 steroidal saponins, aglycon is respectively refined nurse sapogenin, diosgenin, Sarsasapogenin, Smilagenin; Saccharide: glucose, fructose, sucrose etc.
The property of medicine: sweet, bitter, cold.Return lung, kidney channel.Function cures mainly: nourshing Yin and drynsessmoistening prescription, lung heat clearing pathogenic fire reducing.Cure mainly cough caused by dryness-heat, deficiency of YIN chronic cough, consumption of YIN caused by febrile disease, interior-heat is quenched one's thirst, dryness of the intestine constipation, laryngopharynx swelling and pain.
Semen Cuscutae: base is former: be the herb of Convolvulaceae Hellweed Semen Cuscutae.Composition: Semen Cuscutae is containing alkaloid, anthraquinone, coumarin, flavone, glycoside, sterol, tannic acid, saccharide etc.Flavonoid has: Quercetin, astragalin, hyperin; Sterols has: cholesterol, campesterol, cupreol, stigmasterol, β-Amyrin.Also trace element is contained as strontium, molybdenum, calcium, magnesium, ferrum, manganese, zinc, copper etc. and several amino acids (free amino acid in seed and the total amino acids after being hydrolyzed are 5.3%, and wherein the content of essential amino acids accounts for 42.8%).The property of medicine: micro-pungent, sweet, flat, nontoxic.Function cures mainly: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones being applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.
Herba Eupatorii: base is former: be the aerial parts of Compositae feverwort Herba Eupatorii.Composition: 1. Herba Eupatorii herb is containing volatile oil: to P-cymene, neryl acetate, thymol methyl ether.Taraxasterol is contained, taraxasterylacetate, taraxasterol cetylate etc. in flower and leaf.2. Taiwan Herba Eupatorii is containing sesquiterpenoids composition: eupatolide, Herba Euptatorii formosani lactone, 4-hydroxyl-2-methylol-2-butylene acyl Herba Euptatorii formosani lactone.The property of medicine: pungent, flat.Return spleen, stomach warp.Function cures mainly: expelling summer-heat and damp, be amusing and in.Cure mainly heat-damp in summer or hygropyrexia from the beginning of, generate heat nose heave, abdominal distention uncomfortable in chest, gastral cavity painful abdominal mass is not hungry, nausea and vomiting, sweet greasy in mouth, quenches one's thirst.
Corm Eleocharitis: another name Horse hoof, black taro, Di Li.Flavor efficacy: sweet, cold.Function heat clearing away, reduce phlegm, removing food stagnancy, change wart.Be applicable to that epidemic febrile disease is quenched one's thirst, jaundice, pyretic stranguria, mass in the abdomen, conjunctival congestion, laryngopharynx swelling and pain, wart etc.Prevention acute infectious disease, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, diuresis relieving constipation is eliminated the phlegm, help digestion de-swelling, conditioning hemorrhoid or dysentery is had blood in stool, woman uterine bleeding, lung-dryness syndrome due to deficiency of YIN, phlegm-heat cough, discomfort in the throat, mass in the abdomen are gathered, conjunctival congestion is hidden from view, auxiliary effect such as to bring down a fever.In addition, Corm Eleocharitis contains a kind of antiviral substance can suppress epidemic encephalitis, influenza virus, can be used for the propagation preventing epidemic encephalitis and influenza.
Bai Nican: for Holothuriidae Bu Shi joins the entirety belonging to animal Bohadschia argus Jaeger and figure stricture of vagina Bai Nican (removing internal organs).The property of medicine: taste is micro-sweet, warm in nature.Composition: main containing triterpene glycosides, also has the elements such as sodium, potassium, calcium, phosphorus, magnesium, ferrum, zinc.Find according to modern pharmacological research, this medical instrument has effect of sterilization, nourishing YIN to lower pathogenic fire, the kidney invigorating, for diseases such as edema.
Radix Angelicae Sinensis: sweet, pungent, warm, enriches blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.The all cards of main blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Chinese medicine granules of the present invention can not only treat diabetes, the effect regulating blood glucose can also be played, treatment diabetes Be very effective, have no side effect, practicality is wide, the state of an illness not only can be made to be well controlled, to be conducive to the generation preventing many-sided complication such as the heart, brain, kidney, eye, foot, and repair can be played to the body of damage.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1: a kind of Chinese medicine granules for the treatment of the diabetes caused by diabetes, each crude drug is as follows, is weight portion (getting 10g for every part): Maifanitum 3, Herba Lythri Salicariae 6, Oryza glutinosa 12, Radix Raphani 8, Fructus Mori 6, Rhizoma Chuanxiong 5, Semen vignae sinensis 3, Fructus Cannabis 7, the Rhizoma Anemarrhenae 10, Radix Asparagi 3, Semen Cuscutae 9, Herba Eupatorii 5, Corm Eleocharitis 3, Bai Nican 3, Radix Angelicae Sinensis 10.
Treat a Chinese medicine granules for the diabetes caused by diabetes, preparation process is as follows:
1. Maifanitum is placed in the hot water of 80 DEG C, when water temperature is cooled to room temperature, adds Sal, after Sal melts completely, soak 10 minutes, taking-up is placed on clean gauze stand-by;
2. get Radix Angelicae Sinensis and Rhizoma Chuanxiong to clean, drain away the water, high temperature sterilization 1 minute, section, uses rice vinegar uniform spraying, slightly vexed 10 minutes, puts interior the low baking temperature of hot pot dryouied and fry 3 minutes, takes out, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Herba Lythri Salicariae, Fructus Mori, Fructus Cannabis, the Rhizoma Anemarrhenae, Radix Asparagi, Semen Cuscutae, Herba Eupatorii, Corm Eleocharitis and Bai Nican, little fire dries 10 minutes slowly, dries in the air coolly to grind to form smalls, crosses 80 mesh sieves;
4. cleaned by Radix Raphani, the block being cut into coin-size and the Semen vignae sinensis being cut into long 1 centimetre after cleaning mix stand-by;
5. Oryza glutinosa is eluriated 1 time, add the water of Oryza glutinosa weight 8 times, soak after 1 hour and add step 1. gained Maifanitum, big fire adds step 4. gains after boiling, after big fire boils 4 minutes, be blended into cold water, turn slow fire boiling 20 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Radix Raphani and Semen vignae sinensis, Maifanitum is taken out, adds step 2. and 3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 50 DEG C of dryings 10 hours, make granule.
model case one:king XX, female, 45 years old, people from Liaocheng of Shandong Province.Symptom: patient suffers from diabetes for a long time, the symptom of have polydipsia, polyuria, polyphagia, becoming thin, has a meal a lot every day, and health although do not have pain, but made the huge mental pressure of patient's back not as one day in one day.Drinking YUQUAN WAN during one's sickness, but effect is not fine always, in nearest half a year, eats YUQUAN WAN and does not substantially have onset, malaise symptoms aggravates, and household asks about everywhere, learns Chinese medicine granules of the present invention always.
Take embodiment 1 gained Chinese medicine granules, take 5 days, sensation appetite reduces to some extent, polyuria, and polydipsia symptom alleviates; Take 15 days, appetite recovers normal substantially, and polydipsia symptom is alleviated further; Take 15 days, polydipsia transference cure, appetite recovers normal, and patient has laid down psychological burden, and the mental status of people might as well be a lot.
embodiment 2: a kind of Chinese medicine granules for the treatment of the diabetes caused by diabetes, each crude drug is as follows, is weight portion (getting 10g for every part): Maifanitum 9, Herba Lythri Salicariae 12, Oryza glutinosa 25, Radix Raphani 16, Fructus Mori 12, Rhizoma Chuanxiong 15, Semen vignae sinensis 7, Fructus Cannabis 15, the Rhizoma Anemarrhenae 20, Radix Asparagi 9, Semen Cuscutae 15, Herba Eupatorii 15, Corm Eleocharitis 12, Bai Nican 8, Radix Angelicae Sinensis 20.
Treat a Chinese medicine granules for the diabetes caused by diabetes, preparation process is as follows:
1. Maifanitum is placed in the hot water of 100 DEG C, when water temperature is cooled to room temperature, adds Sal, after Sal melts completely, soak 30 minutes, taking-up is placed on clean gauze stand-by;
2. get Radix Angelicae Sinensis and Rhizoma Chuanxiong to clean, drain away the water, high temperature sterilization 5 minutes, section, uses rice vinegar uniform spraying, slightly vexed 10 minutes, puts interior the low baking temperature of hot pot dryouied and fry 8 minutes, takes out, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Herba Lythri Salicariae, Fructus Mori, Fructus Cannabis, the Rhizoma Anemarrhenae, Radix Asparagi, Semen Cuscutae, Herba Eupatorii, Corm Eleocharitis and Bai Nican, little fire dries 30 minutes slowly, dries in the air coolly to grind to form smalls, crosses 120 mesh sieves;
4. cleaned by Radix Raphani, the block being cut into coin-size and the Semen vignae sinensis being cut into long 1-3 centimetre after cleaning mix stand-by;
5. Oryza glutinosa is eluriated 3 times, add the water of Oryza glutinosa weight 12 times, soak after 1 hour and add step 1. gained Maifanitum, big fire adds step 4. gains after boiling, after big fire boils 8 minutes, be blended into cold water, turn slow fire boiling 40 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Radix Raphani and Semen vignae sinensis, Maifanitum is taken out, adds step 2. and 3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 70 DEG C of dryings 18 hours, make granule.
model case two:zhu XX, man, 58 years old, Donga County, Liaocheng of Shandong Province.Symptom: patient suffers from diabetes, eats four meals every day, still often has hunger sensation, although have an enormous appetite, but lean body mass, drink large water gaging every day and can not alleviate thirsty symptom.Through hospital diagnosis be: diabetes complicated diabetes.On ordinary days brew diabetic tea, effect is undesirable, removes examination in hospital, and doctor advised takes gained Chinese medicine granules of the present invention.
Take embodiment 2 gained Chinese medicine granules, take 5 days, thirsty symptom alleviates; Take 15 days, blood glucose is steady, and patient has stopped the blood sugar lowering Western medicine always taken; Take 20 days, thirsty symptom disappears substantially, and patient's appetite also recovers normal, and body weight also increases to some extent; Take 40 days, take period, patient blood glucose is held stationary always, still adheres to so far taking for keeping blood glucose.
embodiment 3:treat a Chinese medicine granules for the diabetes caused by diabetes, each crude drug is as follows, is weight portion (getting 10g for every part): Maifanitum 5, Herba Lythri Salicariae 8, Oryza glutinosa 16, Radix Raphani 12, Fructus Mori 8, Rhizoma Chuanxiong 8, Semen vignae sinensis 4, Fructus Cannabis 10, the Rhizoma Anemarrhenae 13, Radix Asparagi 5, Semen Cuscutae 11, Herba Eupatorii 8, Corm Eleocharitis 5, Bai Nican 4, Radix Angelicae Sinensis 13.
Treat a Chinese medicine granules for the diabetes caused by diabetes, preparation process is as follows:
1. Maifanitum is placed in the hot water of 85 DEG C, when water temperature is cooled to room temperature, adds Sal, after Sal melts completely, soak 15 minutes, taking-up is placed on clean gauze stand-by;
2. get Radix Angelicae Sinensis and Rhizoma Chuanxiong to clean, drain away the water, high temperature sterilization 2 minutes, section, uses rice vinegar uniform spraying, slightly vexed 10 minutes, puts interior the low baking temperature of hot pot dryouied and fry 5 minutes, takes out, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Herba Lythri Salicariae, Fructus Mori, Fructus Cannabis, the Rhizoma Anemarrhenae, Radix Asparagi, Semen Cuscutae, Herba Eupatorii, Corm Eleocharitis and Bai Nican, little fire dries 15 minutes slowly, dries in the air coolly to grind to form smalls, crosses 90 mesh sieves;
4. cleaned by Radix Raphani, the block being cut into coin-size and the Semen vignae sinensis being cut into long 1.5 centimetres after cleaning mix stand-by;
5. Oryza glutinosa is eluriated 1 time, add the water of Oryza glutinosa weight 9 times, soak after 1 hour and add step 1. gained Maifanitum, big fire adds step 4. gains after boiling, after big fire boils 5 minutes, be blended into cold water, turn slow fire boiling 25 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Radix Raphani and Semen vignae sinensis, Maifanitum is taken out, adds step 2. and 3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 55 DEG C of dryings 12 hours, make granule.
embodiment 4:treat a Chinese medicine granules for the diabetes caused by diabetes, each crude drug is as follows, is weight portion (getting 10g for every part): Maifanitum 7, Herba Lythri Salicariae 10, Oryza glutinosa 21, Radix Raphani 14, Fructus Mori 10, Rhizoma Chuanxiong 13, Semen vignae sinensis 6, Fructus Cannabis 12, the Rhizoma Anemarrhenae 18, Radix Asparagi 7, Semen Cuscutae 13, Herba Eupatorii 13, Corm Eleocharitis 10, Bai Nican 6, Radix Angelicae Sinensis 18.
Treat a Chinese medicine granules for the diabetes caused by diabetes, preparation process is as follows:
1. Maifanitum is placed in the hot water of 95 DEG C, when water temperature is cooled to room temperature, adds Sal, after Sal melts completely, soak 25 minutes, taking-up is placed on clean gauze stand-by;
2. get Radix Angelicae Sinensis and Rhizoma Chuanxiong to clean, drain away the water, high temperature sterilization 4 minutes, section, uses rice vinegar uniform spraying, slightly vexed 10 minutes, puts interior the low baking temperature of hot pot dryouied and fry 7 minutes, takes out, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Herba Lythri Salicariae, Fructus Mori, Fructus Cannabis, the Rhizoma Anemarrhenae, Radix Asparagi, Semen Cuscutae, Herba Eupatorii, Corm Eleocharitis and Bai Nican, little fire dries 25 minutes slowly, dries in the air coolly to grind to form smalls, crosses 110 mesh sieves;
4. cleaned by Radix Raphani, the block being cut into coin-size and the Semen vignae sinensis being cut into long 2.5 centimetres after cleaning mix stand-by;
5. Oryza glutinosa is eluriated 3 times, add the water of Oryza glutinosa weight 11 times, soak after 1 hour and add step 1. gained Maifanitum, big fire adds step 4. gains after boiling, after big fire boils 7 minutes, be blended into cold water, turn slow fire boiling 35 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Radix Raphani and Semen vignae sinensis, Maifanitum is taken out, adds step 2. and 3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 65 DEG C of dryings 16 hours, make granule.
model case three:poplar XX, man, 50 years old, people from Jiyang County, Jinan City, Shandong Province.Symptom: patient suffers from II type glycosuria, often feel thirsty, drink a large amount of water every day and still can not alleviate thirsty symptom, number of times of going to toilet every day reaches 20 times, although there is no slight illness, life is brought inconvenience, take other drug and be all of no curative effect, household is very worried, finds gained Chinese medicine granules of the present invention online being not intended to.
Take embodiment 4 gained Chinese medicine granules, take 3 days, thirsty symptom is alleviated to some extent, no longer occurs the sensation of very dry cough after drinking water in a large number; Take 8 days, blood glucose declines, and every day drinks discharge reduction, and number of times of going to toilet decreases many, substantially remains on every day 10 times; Take 30 days, thirsty transference cure, total urination time recovers normal, and blood glucose can held stationary.Have no side effect during taking appearance.
embodiment 5: a kind of Chinese medicine granules for the treatment of the diabetes caused by diabetes, each crude drug is as follows, is weight portion (getting 10g for every part): Maifanitum 6, Herba Lythri Salicariae 9, Oryza glutinosa 18, Radix Raphani 13, Fructus Mori 9, Rhizoma Chuanxiong 10, Semen vignae sinensis 5, Fructus Cannabis 11, the Rhizoma Anemarrhenae 15, Radix Asparagi 6, Semen Cuscutae 12, Herba Eupatorii 11, Corm Eleocharitis 8, Bai Nican 5, Radix Angelicae Sinensis 15.
Treat a Chinese medicine granules for the diabetes caused by diabetes, preparation process is as follows:
1. Maifanitum is placed in the hot water of 90 DEG C, when water temperature is cooled to room temperature, adds Sal, after Sal melts completely, soak 20 minutes, taking-up is placed on clean gauze stand-by;
2. get Radix Angelicae Sinensis and Rhizoma Chuanxiong to clean, drain away the water, high temperature sterilization 3 minutes, section, uses rice vinegar uniform spraying, slightly vexed 10 minutes, puts interior the low baking temperature of hot pot dryouied and fry 6 minutes, takes out, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Herba Lythri Salicariae, Fructus Mori, Fructus Cannabis, the Rhizoma Anemarrhenae, Radix Asparagi, Semen Cuscutae, Herba Eupatorii, Corm Eleocharitis and Bai Nican, little fire dries 20 minutes slowly, dries in the air coolly to grind to form smalls, crosses 100 mesh sieves;
4. cleaned by Radix Raphani, the block being cut into coin-size and the Semen vignae sinensis being cut into long 2 centimetres after cleaning mix stand-by;
5. Oryza glutinosa is eluriated 2 times, add the water of Oryza glutinosa weight 10 times, soak after 1 hour and add step 1. gained Maifanitum, big fire adds step 4. gains after boiling, after big fire boils 6 minutes, be blended into cold water, turn slow fire boiling 30 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Radix Raphani and Semen vignae sinensis, Maifanitum is taken out, adds step 2. and 3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 60 DEG C of dryings 14 hours, make granule.
test example 1embodiment 5 gained treats the clinical practice of the Chinese medicine granules of the diabetes caused by diabetes: screen 150 routine patients in 4 hospitals, wherein women 75 example, male 75 example.Before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes products obtained therefrom of the present invention, and matched group takes the medicine (as the conventional medicine such as YUQUAN WAN, diabetic tea) of the diabetes that other treatment is caused by diabetes.Curative effect situation criterion: cure: after taking this product, malaise symptoms disappears completely; Effective: after taking this product, malaise symptoms alleviates or partial disappearance; Invalid: after taking this product, malaise symptoms is unchanged or recur.Total effectively comprising cures with effective, and result is as shown in table 1.
The checking of embodiment 5 products obtained therefrom therapeutic effect taken by table 1
Therapeutic effect: as apparent from table 1 can, take healing 78 example (78%) that the embodiment of the present invention 5 gained treats the experimental group of the Chinese medicine granules of the diabetes caused by diabetes, effective 20 examples (20%), invalid 2 examples (2%), total effective rate 98%.And the cure rate of matched group only reaches 24%, inefficiency, but up to 30%, takes the matched group that experimental group that gained of the present invention treats the Chinese medicine granules of the diabetes caused by diabetes is obviously better than taking other drug.Chinese medicine granules of the present invention can not only treat the diabetes caused by diabetes, can also regulate blood glucose in the lump, alleviates the body burden of patient, is the ideal Chinese medicine granule of the diabetes that a kind for the treatment of is caused by diabetes.
Claims (10)
1. treat a Chinese medicine granules for the diabetes caused by diabetes, it is characterized in that: each crude drug is as follows, is weight portion: Maifanitum 3-9, Herba Lythri Salicariae 6-12, Oryza glutinosa 12-25, Radix Raphani 8-16, Fructus Mori 6-12, Rhizoma Chuanxiong 5-15, Semen vignae sinensis 3-7, Fructus Cannabis 7-15, Rhizoma Anemarrhenae 10-20, Radix Asparagi 3-9, Semen Cuscutae 9-15, Herba Eupatorii 5-15, Corm Eleocharitis 3-12, Bai Nican 3-8, Radix Angelicae Sinensis 10-20.
2. the Chinese medicine granules of diabetes that caused by diabetes for the treatment of according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Maifanitum 5-7, Herba Lythri Salicariae 8-10, Oryza glutinosa 16-21, Radix Raphani 12-14, Fructus Mori 8-10, Rhizoma Chuanxiong 8-13, Semen vignae sinensis 4-6, Fructus Cannabis 10-12, Rhizoma Anemarrhenae 13-18, Radix Asparagi 5-7, Semen Cuscutae 11-13, Herba Eupatorii 8-13, Corm Eleocharitis 5-10, Bai Nican 4-6, Radix Angelicae Sinensis 13-18.
3. the Chinese medicine granules of diabetes that caused by diabetes for the treatment of according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Maifanitum 6, Herba Lythri Salicariae 9, Oryza glutinosa 18, Radix Raphani 13, Fructus Mori 9, Rhizoma Chuanxiong 10, Semen vignae sinensis 5, Fructus Cannabis 11, the Rhizoma Anemarrhenae 15, Radix Asparagi 6, Semen Cuscutae 12, Herba Eupatorii 11, Corm Eleocharitis 8, Bai Nican 5, Radix Angelicae Sinensis 15.
4. the preparation method of the Chinese medicine granules of the diabetes that the treatment according to any one of claim 1-3 is caused by diabetes, is characterized in that: step is as follows:
1. Maifanitum is placed in the hot water of 80-100 DEG C, when water temperature is cooled to room temperature, adds Sal, after Sal melts completely, soak 10-30 minute (preferably 20 minutes), taking-up is placed on clean gauze stand-by;
2. get Radix Angelicae Sinensis and Rhizoma Chuanxiong to clean, drain away the water, high temperature sterilization 1-5 minute, section, uses rice vinegar uniform spraying, slightly vexed 10 minutes, puts in the hot pot that dryouies and fries 3-8 minute with low baking temperature, take out, and when placing room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Herba Lythri Salicariae, Fructus Mori, Fructus Cannabis, the Rhizoma Anemarrhenae, Radix Asparagi, Semen Cuscutae, Herba Eupatorii, Corm Eleocharitis and Bai Nican, little fire dries 10-30 minute slowly, dries in the air coolly to grind to form smalls, crosses 80-120 mesh sieve (preferably 100 mesh sieves);
4. cleaned by Radix Raphani, the block being cut into coin-size and the Semen vignae sinensis being cut into long 1-3 centimetre after cleaning mix stand-by;
5. Oryza glutinosa is eluriated 1-3 time, add Oryza glutinosa weight 8-12 water doubly, soak after 1 hour and add step 1. gained Maifanitum, big fire adds step 4. gains after boiling, after big fire boils 4-8 minute, be blended into cold water, turn slow fire boiling 20-40 minute, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Radix Raphani and Semen vignae sinensis, Maifanitum is taken out, adds step 2. and 3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste at 50-70 DEG C of dry 10-18 hour, make granule.
5. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: step 1. Maifanitum is placed in the hot water (preferred Maifanitum is placed in the hot water of 90 DEG C) of 85-95 DEG C.
6. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: step 2. high temperature sterilization 2-4 minute (preferred high temperature sterilization 3 minutes).
7. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: step 3. little fire is dried 15-25 minute (preferred little fire dries 20 minutes slowly) slowly.
8. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: 5. step adds Oryza glutinosa weight 9-11 water (preferably adding the water of Oryza glutinosa weight 10 times) doubly.
9. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: step after 5. big fire boils 5-7 minute, is blended into cold water, turns slow fire boiling 25-35 minute (preferred big fire boil 6 minutes after, be blended into cold water, turn slow fire boiling 30 minutes).
10. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: step 6. thick paste, at 55-65 DEG C of dry 12-16 hour, makes granule (preferred thick paste, 60 DEG C of dryings 14 hours, makes granule).
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105582372A (en) * | 2015-09-24 | 2016-05-18 | 赵连江 | Buccal tablets for treating consumptive thirst caused by diabetes and preparation method thereof |
| CN106822637A (en) * | 2017-02-17 | 2017-06-13 | 成都风靡生物科技有限公司 | It is a kind of to treat decoction medicine of diabetes and preparation method thereof |
| CN106822652A (en) * | 2017-03-24 | 2017-06-13 | 成都海青生物科技有限公司 | It is a kind of to treat decoction medicine of diabetes and preparation method thereof |
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| CN106822652A (en) * | 2017-03-24 | 2017-06-13 | 成都海青生物科技有限公司 | It is a kind of to treat decoction medicine of diabetes and preparation method thereof |
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