CN105125928A - External ointment for treating scalds and preparation method - Google Patents
External ointment for treating scalds and preparation method Download PDFInfo
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- CN105125928A CN105125928A CN201510610123.1A CN201510610123A CN105125928A CN 105125928 A CN105125928 A CN 105125928A CN 201510610123 A CN201510610123 A CN 201510610123A CN 105125928 A CN105125928 A CN 105125928A
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Abstract
The invention discloses an external ointment for treating scalds. The external ointment is mainly prepared from the following raw materials in parts by mass: 9 to 15 parts of lotus petiole petiolus, 7 to 16 parts of achnatherum inebrians, 8 to 13 parts of longflower stringbush roots, 6 to 14 parts of delavay raspberry herbs, 9 to 13 parts of sansevieria, 7 to 12 parts of gypsum rubrum, 9 to 14 parts of campsis grandiflora, 7 to 15 parts of ixeris japonica, 8 to 14 parts of cynanchum thesioides, 9 to 12 parts of bracken, 10 to 16 parts of rhizome of henon bamboo shoot, 8 to 15 parts of euonymus macropterus, 7 to 14 parts of rungia pectinata, 9 to 16 parts of camellia and 11 to 15 parts of sedum sarmentosum. According to the external ointment, the raw materials are traditional Chinese medicine plants, have high safety and have no stimulation to the surface of a wound. The external ointment completely conforms to the principle of traditional Chinese medicines, has the effects of cooling and activating blood, diminishing inflammation and relieving pains and has the advantages of good curative effect, high healing speed, infection resistance, low adverse reaction and difficulty in leaving a scar.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of externally used paste and preparation method for the treatment of scald.
Background technology
Burn and scald is the one damage caused by heating power (gas, the liquid or solid of flame, burning heat), electric energy, chemical substance, lonizing radiation etc., in life commonly by boiling water, roll medicated porridge, burn and scald that deep fat, heat steam cause, especially child.Burn and scald should process in time, otherwise not coilable tragedy will be caused to occur, and even affects all one's life of people.Burn and scald by the degree of depth, is generally divided into three degree: 1. once burn and scald: only injure epidermal area, injured skin rubefaction, swelling, feels pain smartly, but anhydrous bubble out existing; 2. two degree of burn and scald: injure skin corium, local is red and swollen, heating, and hurt like hell, has obvious blister; 3. three degree of burn and scald: full thickness skin fat, bone and the muscle comprised below skin is all subject to imitative evil, and skin is burned black, downright bad, pain is inviolent, and partial nerve is damaged.
Publication No. CN104147272A(application number 201410458210.5) Chinese patent literature disclose a kind of burn and scald medicine, comprise Herba veronicastri villosuli 5-15 part, Hibisci Mutabilis 8-15 part, Folium Aloe 3-10 part, Spica Prunellae 5-10 part, Radix Paeoniae Rubra 6-10 part, Rhizoma Impatienis Textori 15-20 part, Corium elephatis 5-15 part, Borneolum Syntheticum 15-20 part, Margarita powder 10-20 part.Publication No. CN104784333A(application number 201410026706.5) Chinese patent literature disclose a kind of burn and scald also face cream, form primarily of Flos Lonicerae 80-120, Cortex Phellodendri 30-90, Rhizoma Polygoni Cuspidati 30-90, little Ilicis Purpureae 30-90, Radix Arnebiae (Radix Lithospermi) 80-120, Radix Et Rhizoma Rhei 70-100, Radix Rehmanniae 80-120, Radix Sanguisorbae 70-100, Scolopendra 70-100, LUBIANHUANG 30-90, Rhizoma Coptidis 30-90, Spora Lygodii 30-90, Oleum Sesami 2000-3000.Publication No. CN104107247A(application number 201310165394.1) Chinese patent literature disclose a kind of burn and scald quick-healing paste, hung grass (stir-baked the crude drugs into black on outside and brown in inside) by Rhizoma Coptidis, Radix Et Rhizoma Rhei (stir-baked the crude drugs into black on outside and brown in inside), stir-baked CORTEX PHELLODENDRI with salt solution (micro-stir-fry), Mirabilitum crystallina, height, forged conch meal, preparation is modulated into unguentum with Oleum sesami and is loaded in vial and forms in proportion.
The topical agent of current treatment burn and scald has many, but its effect is uneven, and some easily stays scar, can not reach satisfied healing effect, therefore, needs the traditional Chinese medical science topical agent developing a kind of determined curative effect to treat burn and scald, helps patient to solve misery.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare the externally used paste and preparation method that treatment that is simple, instant effect scalds.
Technical scheme of the present invention is:
Treat an externally used paste for scald, be prepared from primarily of following bulk drugs, be mass parts: Petiolus nelumbinis 9-15, Herba oxytropis glabrae 7-16, Radix Wikstroemiae Dolichanthae 8-13, Rubus delavayi Franch. 6-14, Folium Sansevieriae Trifasclatae 9-13, Mirabilitum crystallina 7-12, Flos Campsis 9-14, Herba ixeritis debilis 7-15, Herba Cynanchi Thesioidis 8-14, Herba Pteridis Multifidae 9-12, Rhizoma Phyllostachydis henonis 10-16, Cortex Euonymi phellomanis 8-15, Herba rungiae pectinatae 7-14, Flos Camelliae Japonicae 9-16, Herba Sedi 11-15.
In preferred scheme, it is characterized in that, Petiolus nelumbinis 10-14, Herba oxytropis glabrae 9-14, Radix Wikstroemiae Dolichanthae 9-12, Rubus delavayi Franch. 8-12, Folium Sansevieriae Trifasclatae 10-12, Mirabilitum crystallina 9-10, Flos Campsis 10-13, Herba ixeritis debilis 9-13, Herba Cynanchi Thesioidis 10-12, Herba Pteridis Multifidae 10-11, Rhizoma Phyllostachydis henonis 12-14, Cortex Euonymi phellomanis 10-13, Herba rungiae pectinatae 9-12, Flos Camelliae Japonicae 11-14, Herba Sedi 12-14.
Be more preferably, Petiolus nelumbinis 12, Herba oxytropis glabrae 11.5, Radix Wikstroemiae Dolichanthae 10.5, Rubus delavayi Franch. 10, Folium Sansevieriae Trifasclatae 11, Mirabilitum crystallina 9.5, Flos Campsis 11.5, Herba ixeritis debilis 11, Herba Cynanchi Thesioidis 11, Herba Pteridis Multifidae 10.5, Rhizoma Phyllostachydis henonis 13, Cortex Euonymi phellomanis 11.5, Herba rungiae pectinatae 10.5, Flos Camelliae Japonicae 12.5, Herba Sedi 13.
Described a kind of preparation method for the treatment of the externally used paste of scald, step is:
(1) by Flos Campsis and Flos Camelliae Japonicae roguing, refined honey is added and yellow wine is mixed thoroughly (mass ratio of refined honey and yellow wine is 1:4), moistening 10-20 minute (preferred, moistening 12-18 minute; Be more preferably, moistening 15 minutes), be placed in frying pan, slow fire fried dry, take out;
(2) Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi are cleaned, be placed in frying pan, mix thoroughly with rice vinegar, slow fire heats, and fries to the micro-Huang in crude drug surface, takes out, dry in the air cool, pulverized 60-100 mesh sieve and (preferably, pulverized 70-90 mesh sieve; Be more preferably, pulverized 80 mesh sieves), use 75% alcohol dipping, then carry out diafiltration extraction, when collecting the percolate of crude drug quality 20 times, stop diafiltration, be evaporated to 1/4 of original volume;
(3) get Mirabilitum crystallina to clean, break into pieces, be placed in crucible, be calcined to and be popular in, take out, be placed in Rhizoma Zingiberis Recens juice, after cool, take out, grind into powder;
(4) Petiolus nelumbinis, Radix Wikstroemiae Dolichanthae, Rubus delavayi Franch., Folium Sansevieriae Trifasclatae, Herba Cynanchi Thesioidis, Rhizoma Phyllostachydis henonis and Herba rungiae pectinatae roguing are cleaned, decocting in water is added together with step (1) made crude drug, after big fire boils 26-34 minute, Guan Huo, add a cover vexed 1-3 hour (preferably, vexed 1.5-2.5 hour; Be more preferably, vexed 2 hours), filter, collect filtrate;
(5) by made to step (2) (4) concentrated and filtrate mixing, and add step (3) made medicamental pulverata, heated and stirred mixes, and is condensed into thick paste, obtains externally used paste.
Described a kind of preparation method for the treatment of the externally used paste of scald, the gross mass of step (1) refined honey and yellow wine is the 0.4-0.6 of Flos Campsis and Flos Camelliae Japonicae quality sum doubly (preferred, the gross mass of refined honey and yellow wine is 0.5 times of Flos Campsis and Flos Camelliae Japonicae quality sum).
Described a kind of preparation method for the treatment of the externally used paste of scald, the amount of step (2) rice vinegar be Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi gross mass 0.2-0.4 doubly (preferred, the amount of rice vinegar be Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi gross mass 0.3 times).
Described a kind of preparation method for the treatment of the externally used paste of scald, step (2) 75% alcohol dipping 10-15 hour (preferably, dipping 11-14 hour; Be more preferably, flood 12.5 hours).
Described a kind of preparation method for the treatment of the externally used paste of scald, the 6-8 that step (4) amount of water is boiled crude drug gross mass is (preferred, amount of water is 7 times of boiled crude drug gross mass) doubly.
Described a kind of preparation method for the treatment of the externally used paste of scald, step (4) big fire is boiled 28-32 minute (preferred, big fire boils 30 minutes).
Present invention also offers the described a kind of application of externally used paste when preparing the medicine that treatment is scalded for the treatment of scald.
A kind of externally used paste compatibility science for the treatment of scald provided by the invention, preparation is simple, is easy to carry.In addition, excellent results of the present invention also shows:
1, raw material of the present invention is Chinese medicine plant, and safety is high, to wound surface without any stimulation;
2, this prescription meets Chinese medicine principle completely, has the effect such as removing heat from blood and promoting blood circulation, anti-inflammatory analgetic;
3, good effect of the present invention, healing is fast, and infection, untoward reaction is low, not easily stays scar.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1treat an externally used paste for scald, be prepared from (every part of 10g) primarily of following bulk drugs: Petiolus nelumbinis 9 parts, Herba oxytropis glabrae 7 parts, Radix Wikstroemiae Dolichanthae 8 parts, Rubus delavayi Franch. 6 parts, Folium Sansevieriae Trifasclatae 9 parts, Mirabilitum crystallina 7 parts, Flos Campsis 9 parts, Herba ixeritis debilis 7 parts, Herba Cynanchi Thesioidis 8 parts, Herba Pteridis Multifidae 9 parts, Rhizoma Phyllostachydis henonis 10 parts, Cortex Euonymi phellomanis 8 parts, Herba rungiae pectinatae 7 parts, Flos Camelliae Japonicae 9 parts, Herba Sedi 11 parts.
Above-mentioned a kind of preparation method for the treatment of the externally used paste of scald is:
(1) by Flos Campsis and Flos Camelliae Japonicae roguing, add refined honey and yellow wine is mixed thoroughly (mass ratio of refined honey and yellow wine is 1:4, and the gross mass of refined honey and yellow wine is 0.4 times of Flos Campsis and Flos Camelliae Japonicae quality sum), moistening 10 minutes, is placed in frying pan, slow fire fried dry, takes out;
(2) Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi are cleaned, be placed in frying pan, mix thoroughly (amount of rice vinegar is 0.2 times of crude drug gross mass) with rice vinegar, slow fire heats, fry to the micro-Huang in crude drug surface, take out, dry in the air cool, pulverized 60 mesh sieves, by 75% alcohol dipping 10 hours, then carry out diafiltration extraction, when collecting the percolate of crude drug quality 20 times, stop diafiltration, be evaporated to 1/4 of original volume;
(3) get Mirabilitum crystallina to clean, break into pieces, be placed in crucible, be calcined to and be popular in, take out, be placed in Rhizoma Zingiberis Recens juice, after cool, take out, grind into powder;
(4) Petiolus nelumbinis, Radix Wikstroemiae Dolichanthae, Rubus delavayi Franch., Folium Sansevieriae Trifasclatae, Herba Cynanchi Thesioidis, Rhizoma Phyllostachydis henonis and Herba rungiae pectinatae roguing are cleaned, decocting in water (amount of water is 6 times of boiled crude drug gross mass) is added together with step (1) made crude drug, after big fire boils 26 minutes, Guan Huo, add a cover vexed 1 hour, filter, collect filtrate;
(5) by made to step (2) (4) concentrated and filtrate mixing, and add step (3) made medicamental pulverata, heated and stirred mixes, and is condensed into thick paste, obtains externally used paste.
embodiment 2treat an externally used paste for scald, be prepared from (every part of 10g) primarily of following bulk drugs: Petiolus nelumbinis 15 parts, Herba oxytropis glabrae 16 parts, Radix Wikstroemiae Dolichanthae 13 parts, Rubus delavayi Franch. 14 parts, Folium Sansevieriae Trifasclatae 13 parts, Mirabilitum crystallina 12 parts, Flos Campsis 14 parts, Herba ixeritis debilis 15 parts, Herba Cynanchi Thesioidis 14 parts, Herba Pteridis Multifidae 12 parts, Rhizoma Phyllostachydis henonis 16 parts, Cortex Euonymi phellomanis 15 parts, Herba rungiae pectinatae 14 parts, Flos Camelliae Japonicae 16 parts, Herba Sedi 15 parts.
A kind of preparation method for the treatment of the externally used paste of scald is:
(1) by Flos Campsis and Flos Camelliae Japonicae roguing, add refined honey and yellow wine is mixed thoroughly (mass ratio of refined honey and yellow wine is 1:4, and the gross mass of refined honey and yellow wine is 0.6 times of Flos Campsis and Flos Camelliae Japonicae quality sum), moistening 20 minutes, is placed in frying pan, slow fire fried dry, takes out;
(2) Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi are cleaned, be placed in frying pan, mix thoroughly (amount of rice vinegar is 0.4 times of crude drug gross mass) with rice vinegar, slow fire heats, fry to the micro-Huang in crude drug surface, take out, dry in the air cool, pulverized 100 mesh sieves, by 75% alcohol dipping 15 hours, then carry out diafiltration extraction, when collecting the percolate of crude drug quality 20 times, stop diafiltration, be evaporated to 1/4 of original volume;
(3) get Mirabilitum crystallina to clean, break into pieces, be placed in crucible, be calcined to and be popular in, take out, be placed in Rhizoma Zingiberis Recens juice, after cool, take out, grind into powder;
(4) Petiolus nelumbinis, Radix Wikstroemiae Dolichanthae, Rubus delavayi Franch., Folium Sansevieriae Trifasclatae, Herba Cynanchi Thesioidis, Rhizoma Phyllostachydis henonis and Herba rungiae pectinatae roguing are cleaned, decocting in water (amount of water is 8 times of boiled crude drug gross mass) is added together with step (1) made crude drug, after big fire boils 34 minutes, Guan Huo, add a cover vexed 3 hours, filter, collect filtrate;
(5) by made to step (2) (4) concentrated and filtrate mixing, and add step (3) made medicamental pulverata, heated and stirred mixes, and is condensed into thick paste, obtains externally used paste.
Model case: xxx, man, 33 years old.Main suit: right crus of diaphragm is scalded accidentally, local is red and swollen, touches pain, uses erythromycin ointment 3 days, symptom is not alleviated, and occurs festering, and suppurate, surface has faint yellow sepage to ooze out, examination in hospital, light degree Ⅱ is scalded, low grade fever (37.7 DEG C), poor appetite, lassitude, dizzy, use a kind of externally used paste for the treatment of scald of the present embodiment gained, before each use, cleaning wound surface, removes original plaster on wound surface, every day 1 time, thick about 2-3mm, 7 days courses for the treatment of.Use after 3 days, swell and ache and obviously alleviate, stopping of festering, oozes out without pus and sepage, after using a course for the treatment of, ulcer surface major part scabs, and swells and ache and obviously alleviates, after using two courses for the treatment of, and wound surface all healed, foot's skin is pale red, and non-pigment is calm, and without cicatrization, patient fully recovers.
embodiment 3treat an externally used paste for scald, be prepared from (every part of 10g) primarily of following bulk drugs: Petiolus nelumbinis 10 parts, Herba oxytropis glabrae 9 parts, Radix Wikstroemiae Dolichanthae 9 parts, Rubus delavayi Franch. 8 parts, Folium Sansevieriae Trifasclatae 10 parts, Mirabilitum crystallina 9 parts, Flos Campsis 10 parts, Herba ixeritis debilis 9 parts, Herba Cynanchi Thesioidis 10 parts, Herba Pteridis Multifidae 10 parts, Rhizoma Phyllostachydis henonis 12 parts, Cortex Euonymi phellomanis 10 parts, Herba rungiae pectinatae 9 parts, Flos Camelliae Japonicae 11 parts, Herba Sedi 12 parts.
A kind of preparation method for the treatment of the externally used paste of scald is:
(1) by Flos Campsis and Flos Camelliae Japonicae roguing, add refined honey and yellow wine is mixed thoroughly (mass ratio of refined honey and yellow wine is 1:4, and the gross mass of refined honey and yellow wine is 0.4 times of Flos Campsis and Flos Camelliae Japonicae quality sum), moistening 12 minutes, is placed in frying pan, slow fire fried dry, takes out;
(2) Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi are cleaned, be placed in frying pan, mix thoroughly (amount of rice vinegar is 0.2 times of crude drug gross mass) with rice vinegar, slow fire heats, fry to the micro-Huang in crude drug surface, take out, dry in the air cool, pulverized 70 mesh sieves, by 75% alcohol dipping 11 hours, then carry out diafiltration extraction, when collecting the percolate of crude drug quality 20 times, stop diafiltration, be evaporated to 1/4 of original volume;
(3) get Mirabilitum crystallina to clean, break into pieces, be placed in crucible, be calcined to and be popular in, take out, be placed in Rhizoma Zingiberis Recens juice, after cool, take out, grind into powder;
(4) Petiolus nelumbinis, Radix Wikstroemiae Dolichanthae, Rubus delavayi Franch., Folium Sansevieriae Trifasclatae, Herba Cynanchi Thesioidis, Rhizoma Phyllostachydis henonis and Herba rungiae pectinatae roguing are cleaned, decocting in water (amount of water is 6 times of boiled crude drug gross mass) is added together with step (1) made crude drug, after big fire boils 28 minutes, Guan Huo, add a cover vexed 1.5 hours, filter, collect filtrate;
(5) by made to step (2) (4) concentrated and filtrate mixing, and add step (3) made medicamental pulverata, heated and stirred mixes, and is condensed into thick paste, obtains externally used paste.
Model case: xxx, female, 1 years old 3 months.Firm LEARNING TO WALK, steps on enter in hot water basin accidentally, left foot and the exfoliation of ankle place, the visible scarlet scald wound of vola, heel and internal malleolus, dark II degree of scald, has faint yellow sepage to ooze out, can not touch, pain is cry and screamed, and uses a kind of externally used paste for the treatment of scald of the present embodiment gained, cleaning wound surface before each use, remove original plaster on wound surface, every day 1 time, thick about 2-3mm, 7 days courses for the treatment of.Use after 3 days, redness alleviates, and sepage disappears, and after using a course for the treatment of, has large area neoplastic skin to grow around wound surface, after using two courses for the treatment of, wound surface heals substantially, and continue use 3 days, wound surface heals completely, in pale red, non-pigment is calm, and without cicatrization, infant is cured.
embodiment 4treat an externally used paste for scald, be prepared from (every part of 10g) primarily of following bulk drugs: Petiolus nelumbinis 14 parts, Herba oxytropis glabrae 14 parts, Radix Wikstroemiae Dolichanthae 12 parts, Rubus delavayi Franch. 12 parts, Folium Sansevieriae Trifasclatae 12 parts, Mirabilitum crystallina 10 parts, Flos Campsis 13 parts, Herba ixeritis debilis 13 parts, Herba Cynanchi Thesioidis 12 parts, Herba Pteridis Multifidae 11 parts, Rhizoma Phyllostachydis henonis 14 parts, Cortex Euonymi phellomanis 13 parts, Herba rungiae pectinatae 12 parts, Flos Camelliae Japonicae 14 parts, Herba Sedi 14 parts.
A kind of preparation method for the treatment of the externally used paste of scald is:
(1) by Flos Campsis and Flos Camelliae Japonicae roguing, add refined honey and yellow wine is mixed thoroughly (mass ratio of refined honey and yellow wine is 1:4, and the gross mass of refined honey and yellow wine is 0.6 times of Flos Campsis and Flos Camelliae Japonicae quality sum), moistening 18 minutes, is placed in frying pan, slow fire fried dry, takes out;
(2) Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi are cleaned, be placed in frying pan, mix thoroughly (amount of rice vinegar is 0.4 times of crude drug gross mass) with rice vinegar, slow fire heats, fry to the micro-Huang in crude drug surface, take out, dry in the air cool, pulverized 90 mesh sieves, by 75% alcohol dipping 14 hours, then carry out diafiltration extraction, when collecting the percolate of crude drug quality 20 times, stop diafiltration, be evaporated to 1/4 of original volume;
(3) get Mirabilitum crystallina to clean, break into pieces, be placed in crucible, be calcined to and be popular in, take out, be placed in Rhizoma Zingiberis Recens juice, after cool, take out, grind into powder;
(4) Petiolus nelumbinis, Radix Wikstroemiae Dolichanthae, Rubus delavayi Franch., Folium Sansevieriae Trifasclatae, Herba Cynanchi Thesioidis, Rhizoma Phyllostachydis henonis and Herba rungiae pectinatae roguing are cleaned, decocting in water (amount of water is 8 times of boiled crude drug gross mass) is added together with step (1) made crude drug, after big fire boils 32 minutes, Guan Huo, add a cover vexed 2.5 hours, filter, collect filtrate;
(5) by made to step (2) (4) concentrated and filtrate mixing, and add step (3) made medicamental pulverata, heated and stirred mixes, and is condensed into thick paste, obtains externally used paste.
Model case: xxx, man, 24 years old.During end chaffy dish, accidentally scalded by chaffy dish soup, waist and thigh large area are scalded, red and swollen, pain, festers, and have large vesicle to be formed, bleb includes faint yellow supernatant liquid, after vesicle ulceration, the ruddy humidity of wound surface, has part red and white, pain is obvious, and hospital gives treatment to, dark II degree of scald, use a kind of externally used paste for the treatment of scald of the present embodiment gained after carrying out conventional treatment, before each use, cleaning wound surface, removes original plaster on wound surface, every day 1 time, thick about 2-3mm, 7 days courses for the treatment of.Use after 3 days, swell and ache and alleviate, around wound surface, have incrustation to generate, after using a course for the treatment of, the incrustation of wound surface major part, after using two courses for the treatment of, part crust comes off, and neoplastic skin exposes, and after using three courses for the treatment of, wound surface heals completely, in pale red, non-pigment is calm, and without cicatrization, patient cures.
embodiment 5treat an externally used paste for scald, be prepared from (every part of 10g) primarily of following bulk drugs: Petiolus nelumbinis 12 parts, Herba oxytropis glabrae 11.5 parts, Radix Wikstroemiae Dolichanthae 10.5 parts, Rubus delavayi Franch. 10 parts, Folium Sansevieriae Trifasclatae 11 parts, Mirabilitum crystallina 9.5 parts, Flos Campsis 11.5 parts, Herba ixeritis debilis 11 parts, Herba Cynanchi Thesioidis 11 parts, Herba Pteridis Multifidae 10.5 parts, Rhizoma Phyllostachydis henonis 13 parts, Cortex Euonymi phellomanis 11.5 parts, Herba rungiae pectinatae 10.5 parts, Flos Camelliae Japonicae 12.5 parts, Herba Sedi 13 parts.
A kind of preparation method for the treatment of the externally used paste of scald is:
(1) by Flos Campsis and Flos Camelliae Japonicae roguing, add refined honey and yellow wine is mixed thoroughly (mass ratio of refined honey and yellow wine is 1:4, and the gross mass of refined honey and yellow wine is 0.5 times of Flos Campsis and Flos Camelliae Japonicae quality sum), moistening 15 minutes, is placed in frying pan, slow fire fried dry, takes out;
(2) Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi are cleaned, be placed in frying pan, mix thoroughly (amount of rice vinegar is 0.3 times of crude drug gross mass) with rice vinegar, slow fire heats, fry to the micro-Huang in crude drug surface, take out, dry in the air cool, pulverized 80 mesh sieves, by 75% alcohol dipping 12.5 hours, then carry out diafiltration extraction, when collecting the percolate of crude drug quality 20 times, stop diafiltration, be evaporated to 1/4 of original volume;
(3) get Mirabilitum crystallina to clean, break into pieces, be placed in crucible, be calcined to and be popular in, take out, be placed in Rhizoma Zingiberis Recens juice, after cool, take out, grind into powder;
(4) Petiolus nelumbinis, Radix Wikstroemiae Dolichanthae, Rubus delavayi Franch., Folium Sansevieriae Trifasclatae, Herba Cynanchi Thesioidis, Rhizoma Phyllostachydis henonis and Herba rungiae pectinatae roguing are cleaned, decocting in water (amount of water is 7 times of boiled crude drug gross mass) is added together with step (1) made crude drug, after big fire boils 30 minutes, Guan Huo, add a cover vexed 2 hours, filter, collect filtrate;
(5) by made to step (2) (4) concentrated and filtrate mixing, and add step (3) made medicamental pulverata, heated and stirred mixes, and is condensed into thick paste, obtains externally used paste.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Petiolus nelumbinis: base is former: be petiole or the anthocaulus of Flos nymphaeae (Nymphaea teragona Georgi) kind of plant lotus.Nature and flavor: micro-hardship are flat.Gui Jing: enter liver, spleen, stomach warp.Function cures mainly: clearing away summer-heat, and alleviating distention in middle-JIAO is regulated the flow of vital energy.Dizzy for heatstroke, uncomfortable in chest, the stagnation of QI.
Herba oxytropis glabrae: base is former: be the herb of leguminous plant glabrous crazyweed.Function cures mainly: anesthesia, calm, pain relieving.Control arthralgia, toothache, neurasthenia, skin pruritus.
Radix Wikstroemiae Dolichanthae: base is former: for Isolated From Thymelaeaceae Species one is the root of perfume (or spice).Nature and flavor: sweet light are flat.Function cures mainly: spleen invigorating, tonify deficiency. and control insufficiency of the spleen stomach weak, loose stool, the deficiency of vital energy swells lingering.
Rubus delavayi Franch.: base is former: be the Herb of rosaceous plant SANYE Fructus Rubi corchorifolii Immaturus.Nature and flavor: sweet micro-acid are flat.Function cures mainly: heat-clearing and toxic substances removing, dehumidifying dysentery relieving.Drive ascarid.
Folium Sansevieriae Trifasclatae: base is former: be the leaf of Agavaceae plant Folium Sansevieriae Trifasclatae.Nature and flavor: cool in nature, sour in the mouth.Function cures mainly: heat-clearing and toxic substances removing.Cure cold, bronchitis, traumatic injury, skin infection.
Mirabilitum crystallina: base is former: be the crystal of Sulfates mineral Natrii Sulfas.Nature and flavor: Xin Xian, cold.Gui Jing: enter the heart, stomach, kidney channel.Function cures mainly: resolving heat and reducing pathogenic fire, sharp key, detumescence.Row calentura when controlling, accumulated heat excessive thirst, vomits and diarrhoea, edema, urine retention, bleeding from the gum, and erysipelas is scalded.
Flos Campsis: base is former: be the flower of Bignoniaceae plant Radix campsis.Nature and flavor: acid, cold.Gui Jing: enter Liver Channel.Function cures mainly: cooling blood and dissolving stasis.Control amenorrhea due to stagnation of blood, lump in the abdomen, heat in blood pruritus due to wind pathogen, rosacea.
Herba ixeritis debilis: base is former: be the herb of feverfew Herba ixeritis debilis.Nature and flavor: bitter, cold.Function cures mainly: clearing away heat and cooling blood, inducing diuresis to remove edema.For cough due to lung-heat, laryngalgia, oral ulcer, acute conjunctivitis, appendicitis, edema, dysuria, mastitis are controlled in external, furuncle toxic swelling, skin pruritus.
Herba Cynanchi Thesioidis: base is former: be herb and the fruit of Herba seu radix metaplexis kind of plant spire Rhizoma Cynanchi Stauntonii.Nature and flavor: sweet are flat.Function cures mainly: QI invigorating, lactogenesis.For the empty agalactia of body, verruca vulgaris is controlled in external.
Herba Pteridis Multifidae: base is former: be herb or the root of Pteridaceae plant Herba Pteridis Multifidae.Nature and flavor: light, micro-hardship are cool.Gui Jing: enter kidney, stomach two warp.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances dysentery relieving, cooling blood for hemostasis.For dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication, traumatic hemorrhage is controlled in external, burn and scald.
Rhizoma Phyllostachydis henonis: base is former: be the rhizome of grass phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle.Nature and flavor: sweet are light, cold.Function cures mainly: clearing heat and relieving fidgetness, and clearing away phlegm is calmed the frightened.Main heating is vexed, palpitation with fear, pediatric epilepsy scared.
Cortex Euonymi phellomanis: base is former: be the branch skin of Celastraceae plant bolt Cortex Euonymi phellomanis.Nature and flavor: cold in nature, bitter in the mouth.Gui Jing: enter liver, lung two warp.Function cures mainly: removing blood stasis falls tire, regulating menstruation Radix Dipsaci.Control puerperal abdonimal pain, metrorrhagia hematochezia, rheumatalgia.
Herba rungiae pectinatae: base is former: be the herb of acanthaceous plant Herba rungiae pectinatae.Nature and flavor: sweetness and bitterness are cool.Function cures mainly: liver heat removing and eyesight improving, removing food stagnancy dysentery relieving.Treating the liver is scorching, and acute binding film is scorching, food stagnation of child, dysentery, lymphoid tuberculosis.
Flos Camelliae Japonicae: base is former: be the flower of plant of theaceae Flos Camelliae Japonicae.Nature and flavor: pungent, bitter, cold.Gui Jing: enter liver, lung two warp.Function cures mainly: convergence removing heat from blood, hemostasis.For spitting blood, epistaxis, has blood in stool, metrorrhagia, and burn and scald is controlled in external, wound hemorrhage.
Herba Sedi: base is former: be the herb of crassulaceae plants Herba Sedi.Nature and flavor: sweet, light, cool.Gui Jing: return liver, gallbladder, small intestine meridian.Function cures mainly: eliminating damp-heat, removing toxic substances.For jaundice due to damp-heat, dysuria, carbuncle skin infection, acute hepatitis, chronic hepatitis.
test example 1a kind of clinical practice for the treatment of the externally used paste (embodiment 5) of scald of gained of the present invention:
In October ,-2014 in February, 2014, filter out 327 routine patients at 4 hospital's burn and scald traumatologys, wherein women 158 example, male 169 example, age 3-65 year, year mean age (40.5 ± 3.7), scalding area≤30%, scald the degree of depth: light degree Ⅱ 162 example, dark II degree of 107 example, III degree of 58 example.Patient is divided into two groups at random, experimental group 187 example and matched group 140 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.
Patient all carries out fluid infusion according to scalding area and the degree of depth and health, ensures that patient steadily spends shock stage, comparatively serious patient, the antibiotic intravenous drip that application is suitable, until body temperature is normal, and red around wound surface, swollen, pain disappearance.Carry out the original ointment of clean removing to wound surface before coating, experimental group uses products obtained therefrom of the present invention, thick 2-3mm, and every day is changed once, and consumption adjusts to some extent depending on concrete condition, 7 days courses for the treatment of, treats 1-3 the course for the treatment of.Matched group uses other medicine, as ointment for treating burn and scald, except scar cream, scalds wet goods conventional medication.Treatments period carries out Continuous Observation to two groups of patients, observes wounds healing time, pain relief situation, record symptom and change.
Curative effect situation criterion: clinical cure: wound surface heals completely, General Symptoms disappears; Effective: wound healing more than 90%, has cicatrix, General Symptoms disappears; Effective: wound healing more than 50%, has cicatrix, General Symptoms disappears; Invalid: not reach effective standard, traumatic infection fails to control.Total effective rate=(clinical cure+effective)/total number of cases × 100%
Table 1 a liang group patient treatment outcome compare
As shown in Table 1: experimental group patient, clinical cure 153 example, effective 28 examples, experimental group total effective rate 96.8%; In matched group, clinical cure 93 example, effective 29 examples, matched group total effective rate 87.1%, two groups of therapeutic effect have significant difference (P < 0.05).
The comparison of table 2 liang group wounds healing time and pain relieving time
As shown in Table 2, after treatment, experimental group patient pain remission time and wound healing time are all shorter than matched group (P < 0.05).Products made thereby quick result of the present invention is described.
The present invention selects Petiolus nelumbinis alleviating distention in middle-JIAO to regulate the flow of vital energy, Herba oxytropis glabrae sedation-analgesia, Radix Wikstroemiae Dolichanthae spleen invigorating tonify deficiency, Rubus delavayi Franch. and Folium Sansevieriae Trifasclatae heat-clearing and toxic substances removing, Mirabilitum crystallina resolving heat and reducing pathogenic fire, Flos Campsis cooling blood and dissolving stasis, Herba ixeritis debilis clearing away heat and cooling blood, Herba Cynanchi Thesioidis QI invigorating lactogenesis, Herba Pteridis Multifidae clearing away heat-damp and promoting diuresis, Rhizoma Phyllostachydis henonis clearing heat and relieving fidgetness, Cortex Euonymi phellomanis regulating menstruation Radix Dipsaci, Herba rungiae pectinatae liver heat removing and eyesight improving, Flos Camelliae Japonicae convergence removing heat from blood, Herba Sedi eliminating damp-heat, multiple medical material share, and can play the effect such as removing heat from blood and promoting blood circulation, anti-inflammatory analgetic.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat an externally used paste for scald, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Petiolus nelumbinis 9-15, Herba oxytropis glabrae 7-16, Radix Wikstroemiae Dolichanthae 8-13, Rubus delavayi Franch. 6-14, Folium Sansevieriae Trifasclatae 9-13, Mirabilitum crystallina 7-12, Flos Campsis 9-14, Herba ixeritis debilis 7-15, Herba Cynanchi Thesioidis 8-14, Herba Pteridis Multifidae 9-12, Rhizoma Phyllostachydis henonis 10-16, Cortex Euonymi phellomanis 8-15, Herba rungiae pectinatae 7-14, Flos Camelliae Japonicae 9-16, Herba Sedi 11-15.
2. a kind of externally used paste for the treatment of scald as claimed in claim 1, is characterized in that, Petiolus nelumbinis 10-14, Herba oxytropis glabrae 9-14, Radix Wikstroemiae Dolichanthae 9-12, Rubus delavayi Franch. 8-12, Folium Sansevieriae Trifasclatae 10-12, Mirabilitum crystallina 9-10, Flos Campsis 10-13, Herba ixeritis debilis 9-13, Herba Cynanchi Thesioidis 10-12, Herba Pteridis Multifidae 10-11, Rhizoma Phyllostachydis henonis 12-14, Cortex Euonymi phellomanis 10-13, Herba rungiae pectinatae 9-12, Flos Camelliae Japonicae 11-14, Herba Sedi 12-14.
3. a kind of externally used paste for the treatment of scald as claimed in claim 1, is characterized in that, Petiolus nelumbinis 12, Herba oxytropis glabrae 11.5, Radix Wikstroemiae Dolichanthae 10.5, Rubus delavayi Franch. 10, Folium Sansevieriae Trifasclatae 11, Mirabilitum crystallina 9.5, Flos Campsis 11.5, Herba ixeritis debilis 11, Herba Cynanchi Thesioidis 11, Herba Pteridis Multifidae 10.5, Rhizoma Phyllostachydis henonis 13, Cortex Euonymi phellomanis 11.5, Herba rungiae pectinatae 10.5, Flos Camelliae Japonicae 12.5, Herba Sedi 13.
4. a kind of preparation method for the treatment of the externally used paste of scald as described in as arbitrary in claim 1-3, it is characterized in that, step is:
(1) by Flos Campsis and Flos Camelliae Japonicae roguing, refined honey is added and yellow wine is mixed thoroughly (mass ratio of refined honey and yellow wine is 1:4), moistening 10-20 minute (preferred, moistening 12-18 minute; Be more preferably, moistening 15 minutes), be placed in frying pan, slow fire fried dry, take out;
(2) Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi are cleaned, be placed in frying pan, mix thoroughly with rice vinegar, slow fire heats, and fries to the micro-Huang in crude drug surface, takes out, dry in the air cool, pulverized 60-100 mesh sieve and (preferably, pulverized 70-90 mesh sieve; Be more preferably, pulverized 80 mesh sieves), use 75% alcohol dipping, then carry out diafiltration extraction, when collecting the percolate of crude drug quality 20 times, stop diafiltration, be evaporated to 1/4 of original volume;
(3) get Mirabilitum crystallina to clean, break into pieces, be placed in crucible, be calcined to and be popular in, take out, be placed in Rhizoma Zingiberis Recens juice, after cool, take out, grind into powder;
(4) Petiolus nelumbinis, Radix Wikstroemiae Dolichanthae, Rubus delavayi Franch., Folium Sansevieriae Trifasclatae, Herba Cynanchi Thesioidis, Rhizoma Phyllostachydis henonis and Herba rungiae pectinatae roguing are cleaned, decocting in water is added together with step (1) made crude drug, after big fire boils 26-34 minute, Guan Huo, add a cover vexed 1-3 hour (preferably, vexed 1.5-2.5 hour; Be more preferably, vexed 2 hours), filter, collect filtrate;
(5) by made to step (2) (4) concentrated and filtrate mixing, and add step (3) made medicamental pulverata, heated and stirred mixes, and is condensed into thick paste, obtains externally used paste.
5. a kind of preparation method for the treatment of the externally used paste of scald as claimed in claim 4, it is characterized in that, the gross mass of step (1) refined honey and yellow wine is the 0.4-0.6 of Flos Campsis and Flos Camelliae Japonicae quality sum doubly (preferred, the gross mass of refined honey and yellow wine is 0.5 times of Flos Campsis and Flos Camelliae Japonicae quality sum).
6. a kind of preparation method for the treatment of the externally used paste of scald as claimed in claim 4, it is characterized in that, the amount of step (2) rice vinegar be Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi gross mass 0.2-0.4 doubly (preferred, the amount of rice vinegar be Herba oxytropis glabrae, Herba ixeritis debilis, Herba Pteridis Multifidae, Cortex Euonymi phellomanis and Herba Sedi gross mass 0.3 times).
7. a kind of preparation method for the treatment of the externally used paste of scald as claimed in claim 4, is characterized in that, step (2) with 75% alcohol dipping 10-15 hour (preferred, dipping 11-14 hour; Be more preferably, flood 12.5 hours).
8. a kind of preparation method for the treatment of the externally used paste of scald as claimed in claim 4, is characterized in that, the 6-8 that step (4) amount of water is boiled crude drug gross mass is (preferred, amount of water is 7 times of boiled crude drug gross mass) doubly.
9. a kind of preparation method for the treatment of the externally used paste of scald as claimed in claim 4, is characterized in that, step (4) big fire is boiled 28-32 minute (preferred, big fire boils 30 minutes).
10. a kind of application of externally used paste when preparing the medicine that treatment is scalded for the treatment of scald as described in as arbitrary in claim 1-3.
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| CN105597089A (en) * | 2016-02-06 | 2016-05-25 | 陈雷 | Traditional Chinese medicine composition for auxiliary recovery of burns and preparation method of traditional Chinese medicine composition |
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