CN104474045A - Traditional Chinese medicine patch for treating febrile convulsion of infants and preparation method of traditional Chinese medicine patch - Google Patents
Traditional Chinese medicine patch for treating febrile convulsion of infants and preparation method of traditional Chinese medicine patch Download PDFInfo
- Publication number
- CN104474045A CN104474045A CN201410783274.2A CN201410783274A CN104474045A CN 104474045 A CN104474045 A CN 104474045A CN 201410783274 A CN201410783274 A CN 201410783274A CN 104474045 A CN104474045 A CN 104474045A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine patch
- child
- parts
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
- A61K35/10—Peat; Amber; Turf; Humus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine patch for treating febrile convulsion of infants. The traditional Chinese medicine patch is mainly prepared from the following raw materials in parts by weight: 9-12 parts of coralhead plant stem with leaf, 6-9 parts of selenitum, 10-18 parts of forsythia suspense, 9-16 parts of irkutsk anemone rhizome, 10-20 parts of cicada slough, 6-10 parts of carpesium abrotanoides, 8-12 parts of amethyst, 5-10 parts of tylophora florlbunda, 8-15 parts of Japanese peristrophe herb and 4-9 parts of amber. The selected medicinal materials disclosed by the invention are all traditional Chinese medicine materials, and are free of a toxic or side effect; the components completely accord with the principle of the traditional Chinese medicine, and have the efficacies of clearing away heat and toxic materials, expelling wind, relieving convulsion, and tranquilizing and allaying excitement; the prepared patch is used for treating an internal illness by external treatment, and is good in permeability; and side effects on silk infants during drug action can be avoided.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine patch and preparation method for the treatment of child's hyperpyrexia convulsion.
Background technology
Hyperpyrexia convulsion is commonly called as high hot convulsion, is that the modal one of child is fainted from fear.Hyperpyrexia convulsion refers to that children's is early stage at respiratory tract infection or other infectious disease, the convulsions occurred when body temperature raises >=39 DEG C, and gets rid of intracranial infection and other causes the organic or metabolic disease of fainting from fear.Main manifestations is the tatanic or clonic twitches of whole body or the local muscle group occurred suddenly, double eyeball is stared, look side ways, send out straight or on turn over, accompany loss of consciousness.Hyperpyrexia convulsion is divided into pure hyperpyrexia convulsion and Complex anal fistula two kinds.Pure hyperpyrexia convulsion prognosis bona, Complex anal fistula prognosis is then poor.Although the symptom of convulsive attack is very fearful, usual and not serious.When child's adstante febre, the metabolism of neurocyte, oxygen consumption and blood flow can change, and meanwhile, the central nervous system of child also can be in excessive excitatory state.This " excitement " can have influence on child one does not have fully-developed cerebral tissue--and " thalamus ", make it to produce strong electric discharge, and pass to other position of brain, at this moment we will see child's convulsive attack.Febrile convulsion has obvious Inheritance feature, makes child have a kind of tendency being easy to occur to faint from fear.This inherited characteristic causes this convulsions to occur under the effect of the conditions such as special infection environment, physiological process, child's nervous system development imperfection.According to statistics, the child of 3% ~ 4% at least gave birth to a hyperpyrexia convulsion.Most of infant First episode is after birth between 6 months-5 years old, and number of incidences can reduce gradually along with growing up of age, until disappear completely.The cause of disease of hyperpyrexia convulsion still imperfectly understands.Research finds, primary disease has obvious heritability, may be autosomal dominant inheritance, AD, the incomplete penetrance that companion's age is relevant and expressivity.According to age of onset feature, estimate that primary disease penetrance starts to come across about 6 months, the most obvious when 1.5 ~ 2 years old, gradually decline later, be down to low ebb to 4 years old later.The convulsions tendency of genetic determination, in a certain given age stage, is expressed, is namely occurred hyperpyrexia convulsion clinically under the bringing out of caused heatings such as infecting.The traditional Chinese medical science is thought, primary disease is its exopathogenic factor with diseases caused by exogenous pathogenic factor seasonal pathogen, and timid and weak mind, element accumulate liver-heat for its endogenous cause of ill.Publication number CN 102846993 A(application number 201210367745.2) Chinese patent literature disclose children with high fever induced convulsions externally applied ointment, it is with succinum 0.5-2 part, Margarita 2 parts; Calculus Bovis 1 part, Cornu rhinocerotis 1 part, Bombyx Batryticatus 1 part; Periostracum Cicadae 1 part, Bulbus Fritillariae Cirrhosae 1 part, Pericarpium Citri Reticulatae 1 part; Pumex 0.5-1 part; Radix orixae japonicae 2 parts, Fructus Evodiae 0.5-2 part or Concretio Silicea Bambusae 0.5-2 part and/or Arisaema Cum Bile 0.5-2 part, 2 parts, Oryza glutinosa; Fructus Gardeniae 0.5-2 part or Radix Et Rhizoma Rhei 0.5-2 part, Ramulus Uncariae Cum Uncis 0.5-2 part or Rhizoma Gastrodiae 0.5-2 part are that raw material is made.Publication number CN 103800462 A(application number 201210493501.9) Chinese patent literature disclose a kind of Chinese medicine for the treatment of children with high fever induced convulsions, mainly consist of fresh cattle gall bladder, Bombyx Batryticatus, Rhizoma Coptidis, Periostracum Cicadae, component ratio is: fresh cattle gall bladder one piece, Bombyx Batryticatus 25-40%, Rhizoma Coptidis 25-40%, Periostracum Cicadae 25-40%.Publication number CN 104095917 A(application number 201410288027.5) Chinese patent literature disclose a kind of Chinese patent medicine for the treatment of children with high fever induced convulsions and preparation method thereof; comprise: In vitro cultured Calculus Bovis 900-1100 part; Radix Ginseng 850-1150 part; aqua methnae 400-600 part, wherein aqua methnae separately wraps.
Western medicine can make some patients produce certain untoward reaction, and easily recurs, and therapeutic effect is undesirable.The traditional Chinese medical science has about the research of this disease, but much all lacks clinical trial checking, works out a kind ofly to have definite curative effect and can the Chinese medicine formula of anti-recurrence so necessary.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine patch and preparation method for the treatment of child hyperpyrexia convulsion of easy to use, inner disease outer treat.
Technical scheme of the present invention is:
The Chinese medicine patch for the treatment of child hyperpyrexia convulsion, is prepared from primarily of following bulk drugs, is weight portion: Caulis et Folium Abri 9-12, Selenitum 6-9, Fructus Forsythiae 10-18, Rhizoma Anemones Altaicae 9-16, Periostracum Cicadae 10-20, Radix Carpesii 6-10, Fluoritum 8-12, tylophora florlbunda 5-10, Herba Peristrophes 8-15, succinum 4-9.
In preferred scheme, Caulis et Folium Abri 10-11, Selenitum 7-8, Fructus Forsythiae 12-16, Rhizoma Anemones Altaicae 10-15, Periostracum Cicadae 12-18, Radix Carpesii 7-9, Fluoritum 9-11, tylophora florlbunda 7-8, Herba Peristrophes 10-13, succinum 5-8.
Be more preferably, Caulis et Folium Abri 10.5, Selenitum 7.5, Fructus Forsythiae 14, Rhizoma Anemones Altaicae 12.5, Periostracum Cicadae 15, Radix Carpesii 8, Fluoritum 10, tylophora florlbunda 7.5, Herba Peristrophes 11.5, succinum 6.5.
The preparation method of the Chinese medicine patch of described treatment child hyperpyrexia convulsion, step is:
(1) by after Radix Carpesii decontamination, be placed in frying pan, intense fire heats, and fry to surface in burnt brown, spray a little clear water, go out most Mars, and taking-up cools completely;
(2) get Fluoritum decontamination, clean, be placed in crucible, heat with high heat, be calcined to and be popular in, pour in vinegar, shortcake of quenching, take out, then forge and quench once, dry, smash to pieces;
(3) by Caulis et Folium Abri, Selenitum, Fructus Forsythiae, Rhizoma Anemones Altaicae, Periostracum Cicadae, tylophora florlbunda, Herba Peristrophes and succinum, decontamination, cleaning, drying, pulverize and sieve together with step (1) (2) made medical material;
(4) get step (3) made medicated powder 60% loads penetrating bag, is placed in marmite, decocts with water 3 times, merge three filtrates, be concentrated into clear paste;
(5) under room temperature, by the medicated powder of residue 40% and step (4) gained clear paste, stirring and evenly mixing, then add Mentholum and dressing material mixing, obtained mastic, then mastic is coated on medical non-woven fabrics uniformly, make wide 3.5cm, long 5cm, the cream block of thick 2mm, cutting, obtains Chinese medicine patch.
The preparation method of the Chinese medicine patch of described treatment child hyperpyrexia convulsion, the amount of step (2) vinegar is 0.3 times of medical material.
The preparation method of the Chinese medicine patch of described treatment child hyperpyrexia convulsion, step (3) was pulverized 60-100 mesh sieve and (preferably, was pulverized 70-90 mesh sieve; Be more preferably, pulverized 80 mesh sieves).
The preparation method of the Chinese medicine patch of described treatment child hyperpyrexia convulsion, step (4) amount of water is 6 times of medical material weight.
The preparation method of the Chinese medicine patch of described treatment child hyperpyrexia convulsion, step (4) decocting time is that (preferred, decocting time was 40-50 minute in 30-60 minute; Preliminary election more, decocting time is 45 minutes).
The preparation method of the Chinese medicine patch of described treatment child hyperpyrexia convulsion, the relative density of step (4) clear paste is 1.14-1.22(60 DEG C) (preferred, the relative density of clear paste is 1.16-1.20(60 DEG C); Be more preferably, the relative density of clear paste is 1.18(60 DEG C)).
The preparation method of the Chinese medicine patch of described treatment child hyperpyrexia convulsion, the amount of step (5) Mentholum is 0.1 times of clear paste.
The Chinese medicine patch scientific formula for the treatment of child hyperpyrexia convulsion provided by the invention, preparation method is simple, easy to use, be easy to carry.In addition, excellent results of the present invention also shows:
1, selected materials is all Chinese medicine material, without any side effects;
2, this prescription meets Chinese medicine principle completely, has heat-clearing and toxic substances removing, expellings wind and relieving convulsion, effects of tranquilizing and allaying excitement;
3, patch inner disease outer treat of the present invention, good penetrability, when can avoid drug effect, to the side effect of infant.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Caulis et Folium Abri: base is former: be the stem and leaf of pulse family Abrus plant Semen Abri Precatorii.Composition: containing triterpene saponin in yearning between lovers cotyledon: Semen Abri Precatorii triterpene glycosides A, B, C, D.Flavonoid: 5,7,4 '-trihydroxy flavane glycosides, star-spangled banner pinaster-3-glucoside, glycyrrhizin, again containing Semen Abri Precatorii lactone A, etc.The property of medicine: " Guangxi Chinese herbal medicine ": " sweet in the mouth, property is put down." function cures mainly: heat-clearing and toxic substances removing, diuresis.Cure mainly flu, laryngopharynx swelling and pain, cough due to lung-heat, acute mastitis, furuncle, hepatitis.
Selenitum: base is former: be year tied little shape sheet form gypsum Ore of a specified duration.Nature and flavor: salty; Cold.Gui Jing: kidney; Spleen; Stomach warp.Function cures mainly: YIN nourishing; Pathogenic fire reducing; Softening the hard mass; Expectorant.Main overabundance of YANG leading to deficiency of YIN; High fever excessive thirst; Wind syndrome of head headache; Conjunctival congestion is hidden from view; Congenital deformity of the tongue; Swollen and rigid tongue; Laryngopharynx swelling and pain; Head sore; Burn due to hot liquid or fire.
Fructus Forsythiae: base is former: be the dry fruit of Oleaceae plants Fructus Forsythiae.Nature and flavor: bitter, are slightly cold.Gui Jing: return lung, the heart, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Rhizoma Anemones Altaicae: base is former: the root stock of Ranunculaceae thimbleweed anemone altaica.Nature and flavor: pungent, flat or tepor.Gui Jing: enter the heart, liver, spleen channel.Fresh goods strong flavor, pungent loose power more wins than dry product, therefore the good merchantable brand for declaring gas sensible.Function cures mainly: this product had both been longer than removing dampness by means of aromatics, activating spleen and strengthening stomach, is used for the treatment of cloudy stagnant middle Jiao of turbid damp, vexed swollen, all diseases of anorexia of functional activity of QI being not smooth, breast gastral cavity; And again can fragrant magnificent expectorant turbid, resuscitation inducing and mind tranquilizing, is used for the treatment of the mind that turbid damp hoodwinks clearly caused by key dazed and confused, the disease of white and greasy fur; And arrogate to oneself the unconsciousness controlled expectorant heat and fall caused by stagnant pericardium, the diseases such as tic.
Periostracum Cicadae: base is former: exuviae shell when the larva for cicada Cryptotympana atrata Fabr. sprouts wings.Nature and flavor: sweet, cold.Gui Jing: return lung, Liver Channel.Function cures mainly: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Radix Carpesii: base is former: be the herb of Compositae Carpesium plant Radix Carpesii.Composition: herb is containing sesquiterpene lactones: Carabrone, carpesia-lactone, great Ye alantolactone, according to watt centautin, carpesia-lactone alcohol, axil Sheng Yiwa centautin, Telekin etc.The property of medicine: bitter, acrid, cold.Return liver, lung meridian.Function cures mainly: removing heat-phlegm, and removing toxic substances parasite killing, removing blood stasis with potent drugs stops blooding.Cure mainly tonsillitis sore throat, anxious chronic infantile convulsion, toothache, furuncle swells and ache, hemorrhoid complicated by anal fistula, itchy skin eruption, venom, malnutrition due to parasitic infestation, abdominal mass due to blood stasis, spits blood, epistaxis, stranguria with blood, wound hemorrhage.
Fluoritum: base is former: be halogen compounds fluorides fluorite race mineral fluorite.Composition: main fluorinated calcium, sterling kind calcium accounts for 51.2%, and fluorine accounts for 48.8%, but is often mingled with the ferrum oxide of trace.And accompany chromium, copper, manganese, lead, zinc etc.; Even mixing has the elements such as uranium.The property of medicine: sweet, acrid, warm.GUIXIN, liver, lung, kidney channel.Function cures mainly: relieving palpitation is calmed the frightened, and warming the lung sending down the abnormal ascending QI, cold expelling warms up palace.Cure mainly cardiopalmus, seized with terror swollen, infantile convulsion, lung cold cough with dyspnea, woman's infertility.
Tylophora florlbunda: base is former: be the root of asclepiadaceae Tylophora plant tylophora florlbunda.Composition: containing 2,3,5,6-tetramethoxyphenanthro[9,10:6',7' and tylophorine.The property of medicine: pungent, temperature.Mild toxicity.Function cures mainly: dispelling pathogenic wind and eliminating phlegm, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling.Cure mainly cough with asthma abundant expectoration, diphtheria, infantile convulsion, rheumatic arthralgia, traumatic injury, fracture, venom, carbuncle furuncle, acute conjunctivitis, stomatitis, edema, hepatosplenomegaly.
Herba Peristrophes: base is former: be the herb of Acanthaceae Herba Peristrophes platymiscium Herba Peristrophes.Composition: aerial parts is containing the black alcohols of plant: lupeol, stigmasterol, cupreol glucosides, cupreol glucoside.Pharmacology: antibacterial action Herba Peristrophes has stronger inhibitory action to staphylococcus aureus, Hemolytic streptococcus, the false single bacteria of Aerugo, klebsiella pneumoniae.The property of medicine: pungent, cool.Function cures mainly: expelling wind and clearing away heat, cool liver arresting convulsion, removing toxic substances and promoting subsidence of swelling.Cure mainly cold, fever, lung-heat cough with asthma, liver-heat conjunctival congestion, infantile convulsion, laryngopharynx swelling and pain, toxic swelling, hemorrhoid, snake bite and insect sting, traumatic injury.
Succinum: base is former: be the resin of Pinaceae pine genus plant in ancient times, is imbedded in the fossil sample material that underground is transformed year in year out for a long time.Composition: mainly resinous, volatile oil, diabietionlic acid, succinosilvic acid, amber tree fat acid, succinoabietol, succinic acid, Borneolum Syntheticum etc.The property of medicine: sweet, flat.GUIXIN, liver, urinary bladder channel.Function cures mainly: tranquillizing the mind by relieving convulsion, and dissipating blood stasis stops blooding, relieving stranguria by diuresis, nebula of dispelling improving eyesight.Cure mainly insomnia, palpitation with fear, infantile convulsion, epilepsy, congestion amenorrhea, puerperal abdonimal pain ， lumps in the chest and abdomen, stranguria with blood hematuria, the raw cataracta of order.Compatibility and incompatibility of drugs: yin asthenia generating intrinsic heat and without the careful clothes of the stagnant person of the stasis of blood.
embodiment 1the Chinese medicine patch for the treatment of child hyperpyrexia convulsion, is prepared from primarily of following bulk drugs: Caulis et Folium Abri 9g, Selenitum 6g, Fructus Forsythiae 10g, Rhizoma Anemones Altaicae 9g, Periostracum Cicadae 10g, Radix Carpesii 6g, Fluoritum 8g, tylophora florlbunda 5g, Herba Peristrophes 8g, succinum 4g.
The preparation method of the Chinese medicine patch of above-mentioned treatment child hyperpyrexia convulsion is:
(1) by after Radix Carpesii decontamination, be placed in frying pan, intense fire heats, and fry to surface in burnt brown, spray a little clear water, go out most Mars, and taking-up cools completely;
(2) get Fluoritum decontamination, clean, be placed in crucible, heat with high heat, be calcined to and be popular in, pour in the vinegar of medical material 0.3 times, shortcake of quenching, take out, then forge and quench once, dry, smash to pieces;
(3) by Caulis et Folium Abri, Selenitum, Fructus Forsythiae, Rhizoma Anemones Altaicae, Periostracum Cicadae, tylophora florlbunda, Herba Peristrophes and succinum, decontamination, cleaning, drying, pulverized 60 mesh sieves together with step (1) (2) made medical material;
(4) get step (3) made medicated powder 60% loads penetrating bag, and be placed in marmite, add the soak by water 3 times of medical material weight 6 times, each 30 minutes, merge three filtrates, being concentrated into relative density is 1.14(60 DEG C) clear paste;
(5) under room temperature, by the medicated powder of residue 40% and step (4) gained clear paste, stirring and evenly mixing, then the Mentholum and the auxiliary materials and mixing that add clear paste 0.1 times, obtained mastic, then mastic is coated on medical non-woven fabrics uniformly, make wide 3.5cm, long 5cm, the cream block of thick 2mm, cutting, obtains Chinese medicine patch.
embodiment 2the Chinese medicine patch for the treatment of child hyperpyrexia convulsion, is prepared from primarily of following bulk drugs: Caulis et Folium Abri 12g, Selenitum 9g, Fructus Forsythiae 18g, Rhizoma Anemones Altaicae 16g, Periostracum Cicadae 20g, Radix Carpesii 10g, Fluoritum 12g, tylophora florlbunda 10g, Herba Peristrophes 15g, succinum 9g.
The preparation method of the Chinese medicine patch for the treatment of child hyperpyrexia convulsion is:
(1) by after Radix Carpesii decontamination, be placed in frying pan, intense fire heats, and fry to surface in burnt brown, spray a little clear water, go out most Mars, and taking-up cools completely;
(2) get Fluoritum decontamination, clean, be placed in crucible, heat with high heat, be calcined to and be popular in, pour in the vinegar of medical material 0.3 times, shortcake of quenching, take out, then forge and quench once, dry, smash to pieces;
(3) by Caulis et Folium Abri, Selenitum, Fructus Forsythiae, Rhizoma Anemones Altaicae, Periostracum Cicadae, tylophora florlbunda, Herba Peristrophes and succinum, decontamination, cleaning, drying, pulverized 100 mesh sieves together with step (1) (2) made medical material;
(4) get step (3) made medicated powder 60% loads penetrating bag, and be placed in marmite, add the soak by water 3 times of medical material weight 6 times, each 60 minutes, merge three filtrates, being concentrated into relative density is 1.22(60 DEG C) clear paste;
(5) under room temperature, by the medicated powder of residue 40% and step (4) gained clear paste, stirring and evenly mixing, then the Mentholum and the auxiliary materials and mixing that add clear paste 0.1 times, obtained mastic, then mastic is coated on medical non-woven fabrics uniformly, make wide 3.5cm, long 5cm, the cream block of thick 2mm, cutting, obtains Chinese medicine patch.
Model case: xxx, female, 4 years old.There is heating 39 DEG C without obvious inducement, eat febrifuge, DeGrain, generated heat for 1 night, with tic 2 times, morning next day brings down a fever not yet, the head of a family worries, goes to a doctor in township doctor, intramuscular injection antibiotics, after 2 hours, crying and screaming appears again in infant, and mouth magnifies, and does not utter a word, head head rises, and in typical opisthotonus shape, fainting from fear twitches sends out again, after go to a doctor in institute of traditional Chinese medicine, the head of a family has denied family's medical history, is diagnosed as pure hyperpyrexia convulsion on inspection.
Use the Chinese medicine patch of the present embodiment gained treatment child hyperpyrexia convulsion, each one pastes, and is affixed on the acupuncture point places such as umbilicus, the middle of the forehead, the space between the eyebrows, within every 12 hours, changes once.After using half an hour, infant starts stopping and crying and screaming, and after when two, body temperature is down to 38 DEG C, the infant mental status is good, energy normal communication, and after one day, infant is again without convulsions tic symptom, body temperature also recovers normal, after continue again to employ one week, infant rehabilitation, and a year has no recurrence.
embodiment 3the Chinese medicine patch for the treatment of child hyperpyrexia convulsion, is prepared from primarily of following bulk drugs: Caulis et Folium Abri 10g, Selenitum 7g, Fructus Forsythiae 12g, Rhizoma Anemones Altaicae 10g, Periostracum Cicadae 12g, Radix Carpesii 7g, Fluoritum 9g, tylophora florlbunda 7g, Herba Peristrophes 10g, succinum 5g.
The preparation method of the Chinese medicine patch for the treatment of child hyperpyrexia convulsion is:
(1) by after Radix Carpesii decontamination, be placed in frying pan, intense fire heats, and fry to surface in burnt brown, spray a little clear water, go out most Mars, and taking-up cools completely;
(2) get Fluoritum decontamination, clean, be placed in crucible, heat with high heat, be calcined to and be popular in, pour in the vinegar of medical material 0.3 times, shortcake of quenching, take out, then forge and quench once, dry, smash to pieces;
(3) by Caulis et Folium Abri, Selenitum, Fructus Forsythiae, Rhizoma Anemones Altaicae, Periostracum Cicadae, tylophora florlbunda, Herba Peristrophes and succinum, decontamination, cleaning, drying, pulverized 70 mesh sieves together with step (1) (2) made medical material;
(4) get step (3) made medicated powder 60% loads penetrating bag, and be placed in marmite, add the soak by water 3 times of medical material weight 6 times, each 40 minutes, merge three filtrates, being concentrated into relative density is 1.16(60 DEG C) clear paste;
(5) under room temperature, by the medicated powder of residue 40% and step (4) gained clear paste, stirring and evenly mixing, then the Mentholum and the auxiliary materials and mixing that add clear paste 0.1 times, obtained mastic, then mastic is coated on medical non-woven fabrics uniformly, make wide 3.5cm, long 5cm, the cream block of thick 2mm, cutting, obtains Chinese medicine patch.
Model case: xxx, man, 6 years old.After it cyclostrophic is cool, goes out to play, catch a cold, occurred suddenly high heat last night, body temperature 38.7 DEG C, after take medicine after, body temperature slightly falls, infant fall asleep, next day wakes up, and body temperature is 38.8 DEG C, occur the tonic convulsion of whole body muscle group rear half an hour, double eyeball is looked side ways, loss of consciousness, shows effect after 5 minutes and stops.Father and mother are delivered to hospital admission then, are diagnosed as the hyperpyrexia convulsion that respiratory tract infection causes on inspection.
Use the Chinese medicine patch of the present embodiment gained treatment child hyperpyrexia convulsion, each one pastes, and is affixed on the acupuncture point places such as umbilicus, the middle of the forehead, the space between the eyebrows, adopts every 12 hours and changes once.After using half an hour, infant body temperature starts to decline, and spirit takes a turn for the better, and faint from fear and controlled, after using one week, hyperpyrexia convulsion symptom does not appear in patient again, and respiratory tract infection also alleviates to some extent, occurs that high heat also has no recurrence in 1 year.
embodiment 4the Chinese medicine patch for the treatment of child hyperpyrexia convulsion, is prepared from primarily of following bulk drugs: Caulis et Folium Abri 11g, Selenitum 8g, Fructus Forsythiae 16g, Rhizoma Anemones Altaicae 15g, Periostracum Cicadae 18g, Radix Carpesii 9g, Fluoritum 11g, tylophora florlbunda 8g, Herba Peristrophes 13g, succinum 8g.
The preparation method of the Chinese medicine patch for the treatment of child hyperpyrexia convulsion is:
(1) by after Radix Carpesii decontamination, be placed in frying pan, intense fire heats, and fry to surface in burnt brown, spray a little clear water, go out most Mars, and taking-up cools completely;
(2) get Fluoritum decontamination, clean, be placed in crucible, heat with high heat, be calcined to and be popular in, pour in the vinegar of medical material 0.3 times, shortcake of quenching, take out, then forge and quench once, dry, smash to pieces;
(3) by Caulis et Folium Abri, Selenitum, Fructus Forsythiae, Rhizoma Anemones Altaicae, Periostracum Cicadae, tylophora florlbunda, Herba Peristrophes and succinum, decontamination, cleaning, drying, pulverized 90 mesh sieves together with step (1) (2) made medical material;
(4) get step (3) made medicated powder 60% loads penetrating bag, and be placed in marmite, add the soak by water 3 times of medical material weight 6 times, each 50 minutes, merge three filtrates, being concentrated into relative density is 1.20(60 DEG C) clear paste;
(5) under room temperature, by the medicated powder of residue 40% and step (4) gained clear paste, stirring and evenly mixing, then the Mentholum and the auxiliary materials and mixing that add clear paste 0.1 times, obtained mastic, then mastic is coated on medical non-woven fabrics uniformly, make wide 3.5cm, long 5cm, the cream block of thick 2mm, cutting, obtains Chinese medicine patch.
embodiment 5the Chinese medicine patch for the treatment of child hyperpyrexia convulsion, is prepared from primarily of following bulk drugs: Caulis et Folium Abri 10.5g, Selenitum 7.5g, Fructus Forsythiae 14g, Rhizoma Anemones Altaicae 12.5g, Periostracum Cicadae 15g, Radix Carpesii 8g, Fluoritum 10g, tylophora florlbunda 7.5g, Herba Peristrophes 11.5g, succinum 6.5g.
The preparation method of the Chinese medicine patch for the treatment of child hyperpyrexia convulsion is:
(1) by after Radix Carpesii decontamination, be placed in frying pan, intense fire heats, and fry to surface in burnt brown, spray a little clear water, go out most Mars, and taking-up cools completely;
(2) get Fluoritum decontamination, clean, be placed in crucible, heat with high heat, be calcined to and be popular in, pour in the vinegar of medical material 0.3 times, shortcake of quenching, take out, then forge and quench once, dry, smash to pieces;
(3) by Caulis et Folium Abri, Selenitum, Fructus Forsythiae, Rhizoma Anemones Altaicae, Periostracum Cicadae, tylophora florlbunda, Herba Peristrophes and succinum, decontamination, cleaning, drying, pulverized 80 mesh sieves together with step (1) (2) made medical material;
(4) get step (3) made medicated powder 60% loads penetrating bag, and be placed in marmite, add the soak by water 3 times of medical material weight 6 times, each 45 minutes, merge three filtrates, being concentrated into relative density is 1.18(60 DEG C) clear paste;
(5) under room temperature, by the medicated powder of residue 40% and step (4) gained clear paste, stirring and evenly mixing, then the Mentholum and the auxiliary materials and mixing that add clear paste 0.1 times, obtained mastic, then mastic is coated on medical non-woven fabrics uniformly, make wide 3.5cm, long 5cm, the cream block of thick 2mm, cutting, obtains Chinese medicine patch.
test example 1the clinical practice of the Chinese medicine patch of embodiment 5 gained treatment child hyperpyrexia convulsion:
364 routine febrile convulsion infantss are filtered out, wherein women 185 example, male 179 example, oldest 6 years old, minimal ages 2 years old, 3.9 years old mean age in pediatric hospital emergency room.The protopathy of these infants is respiratory tract infection.Diagnostic criteria: the neural academic conference symposium of main reference nineteen eighty-three whole nation children's is about hyperpyrexia convulsion diagnostic criteria.
Test method: patient is divided into two groups at random, experimental group and matched group, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group uses embodiment 5 products obtained therefrom, and each one pastes, and is affixed on the acupuncture point places such as umbilicus, the middle of the forehead, the space between the eyebrows, adopts every 12 hours and changes once, and matched group takes other medicine (protecting the conventional medication such as baby is loose, giant silkworm sheet, Cornu Saigae Tataricae oral liquid).Treatments period carries out Continuous Observation to two groups of patients, record symptom and change, and after treating one week, statistics therapeutic outcome, drug withdrawal follows up a case by regular visits to 1 year.
Curative effect situation criterion: cure: clinical symptom disappearance, follows up a case by regular visits to after drug withdrawal 1 year or four high heat nothings are fainted from fear, and electroencephalogram is normal; Effective: clinical symptoms is obviously improved, follow up a case by regular visits to 1 year after drug withdrawal or highly hanker generation of once fainting from fear four times, the normal or mile abnormality of electroencephalogram; Invalid: clinical malaise symptoms is unchanged, meet sense frver convulsions and still show effect.Result is as shown in table 1.
Table 1 liang component group situation and infant therapeutic outcome
As shown in Table 1: the experimental group infant using embodiment 5 gained Chinese medicine patch, after treatment, malaise symptoms is all eliminated and is had 179 examples (67.8%), infant 77 example (29.2%) that symptom is obviously improved, experimental group total effective rate 97.0% without what recur.The total effective rate of matched group is 78.0%, and therapeutic effect is starkly lower than experimental group, and in following up a case by regular visits to, also comparatively experimental group is high for relapse rate.
The Caulis et Folium Abri heat-clearing and toxic substances removing that the present invention selects, Selenitum nourishing YIN to lower pathogenic fire, Fructus Forsythiae dispersing swelling and dissipating binds, Rhizoma Anemones Altaicae resuscitation inducing and mind tranquilizing, Periostracum Cicadae falls apart wind heat extraction, Radix Carpesii removing heat-phlegm, Fluoritum relieving palpitation is calmed the frightened, tylophora florlbunda dispelling pathogenic wind and eliminating phlegm, Psychotria rubra (Lour.) Poir. lion grass expelling wind and clearing away heat, succinum tranquillizing and allaying excitement, all medicines use together, to the convulsions that high heat causes, show heat-clearing and toxic substances removing, expelling wind and relieving convulsion, effects of tranquilizing and allaying excitement, the timely and effective alleviation infant symptom of energy, and Chinese medicine formula treating both the principal and secondary aspects of a disease, can effectively anti-recurrence.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the Chinese medicine patch of child's hyperpyrexia convulsion, it is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Caulis et Folium Abri 9-12, Selenitum 6-9, Fructus Forsythiae 10-18, Rhizoma Anemones Altaicae 9-16, Periostracum Cicadae 10-20, Radix Carpesii 6-10, Fluoritum 8-12, tylophora florlbunda 5-10, Herba Peristrophes 8-15, succinum 4-9.
2. the Chinese medicine patch for the treatment of child as claimed in claim 1 hyperpyrexia convulsion, is characterized in that, Caulis et Folium Abri 10-11, Selenitum 7-8, Fructus Forsythiae 12-16, Rhizoma Anemones Altaicae 10-15, Periostracum Cicadae 12-18, Radix Carpesii 7-9, Fluoritum 9-11, tylophora florlbunda 7-8, Herba Peristrophes 10-13, succinum 5-8.
3. the Chinese medicine patch for the treatment of child as claimed in claim 1 hyperpyrexia convulsion, is characterized in that, Caulis et Folium Abri 10.5, Selenitum 7.5, Fructus Forsythiae 14, Rhizoma Anemones Altaicae 12.5, Periostracum Cicadae 15, Radix Carpesii 8, Fluoritum 10, tylophora florlbunda 7.5, Herba Peristrophes 11.5, succinum 6.5.
4. the preparation method of the Chinese medicine patch of the treatment child hyperpyrexia convulsion as described in as arbitrary in claim 1-3, it is characterized in that, step is:
(1) by after Radix Carpesii decontamination, be placed in frying pan, intense fire heats, and fry to surface in burnt brown, spray a little clear water, go out most Mars, and taking-up cools completely;
(2) get Fluoritum decontamination, clean, be placed in crucible, heat with high heat, be calcined to and be popular in, pour in vinegar, shortcake of quenching, take out, then forge and quench once, dry, smash to pieces;
(3) by Caulis et Folium Abri, Selenitum, Fructus Forsythiae, Rhizoma Anemones Altaicae, Periostracum Cicadae, tylophora florlbunda, Herba Peristrophes and succinum, decontamination, cleaning, drying, pulverize and sieve together with step (1) (2) made medical material;
(4) get step (3) made medicated powder 60% loads penetrating bag, is placed in marmite, decocts with water 3 times, merge three filtrates, be concentrated into clear paste;
(5) under room temperature, by the medicated powder of residue 40% and step (4) gained clear paste, stirring and evenly mixing, then add Mentholum and dressing material mixing, obtained mastic, then mastic is coated on medical non-woven fabrics uniformly, make wide 3.5cm, long 5cm, the cream block of thick 2mm, cutting, obtains Chinese medicine patch.
5. the preparation method of the Chinese medicine patch for the treatment of child as claimed in claim 4 hyperpyrexia convulsion, it is characterized in that, the amount of step (2) vinegar is 0.3 times of medical material.
6. the preparation method of the Chinese medicine patch for the treatment of child as claimed in claim 4 hyperpyrexia convulsion, it is characterized in that, step (3) was pulverized 60-100 mesh sieve and (preferably, was pulverized 70-90 mesh sieve; Be more preferably, pulverized 80 mesh sieves).
7. the preparation method of the Chinese medicine patch for the treatment of child as claimed in claim 4 hyperpyrexia convulsion, it is characterized in that, step (4) amount of water is 6 times of medical material weight.
8. the preparation method of the Chinese medicine patch for the treatment of child as claimed in claim 4 hyperpyrexia convulsion, is characterized in that, step (4) decocting time is that (preferred, decocting time was 40-50 minute in 30-60 minute; Preliminary election more, decocting time is 45 minutes).
9. the preparation method of the Chinese medicine patch for the treatment of child as claimed in claim 4 hyperpyrexia convulsion, it is characterized in that, the relative density of step (4) clear paste is 1.14-1.22(60 DEG C) (preferred, the relative density of clear paste is 1.16-1.20(60 DEG C); Be more preferably, the relative density of clear paste is 1.18(60 DEG C)).
10. the preparation method of the Chinese medicine patch for the treatment of child as claimed in claim 4 hyperpyrexia convulsion, it is characterized in that, the amount of step (5) Mentholum is 0.1 times of clear paste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410783274.2A CN104474045A (en) | 2014-12-18 | 2014-12-18 | Traditional Chinese medicine patch for treating febrile convulsion of infants and preparation method of traditional Chinese medicine patch |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410783274.2A CN104474045A (en) | 2014-12-18 | 2014-12-18 | Traditional Chinese medicine patch for treating febrile convulsion of infants and preparation method of traditional Chinese medicine patch |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104474045A true CN104474045A (en) | 2015-04-01 |
Family
ID=52748746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410783274.2A Pending CN104474045A (en) | 2014-12-18 | 2014-12-18 | Traditional Chinese medicine patch for treating febrile convulsion of infants and preparation method of traditional Chinese medicine patch |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104474045A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840793A (en) * | 2015-05-27 | 2015-08-19 | 济南方宇文化传媒有限公司 | Pure traditional Chinese medicine cooling gel sheet for high fever of kids and method for preparing same |
| CN108379511A (en) * | 2018-04-24 | 2018-08-10 | 烟台金蕊女性用品有限公司 | A kind of preparation process of Chinese medicine application cream that alleviating menalgia |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101773650A (en) * | 2010-04-19 | 2010-07-14 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating clonic convulsion and preparation method thereof |
| CN101810525A (en) * | 2009-11-26 | 2010-08-25 | 方建国 | Multifunctional shape-protecting health-care medicinal pillow for infant |
-
2014
- 2014-12-18 CN CN201410783274.2A patent/CN104474045A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810525A (en) * | 2009-11-26 | 2010-08-25 | 方建国 | Multifunctional shape-protecting health-care medicinal pillow for infant |
| CN101773650A (en) * | 2010-04-19 | 2010-07-14 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating clonic convulsion and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 常小荣 伦新主编: "《壮医点灸疗法》", 30 September 2012, 中国医药科技出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840793A (en) * | 2015-05-27 | 2015-08-19 | 济南方宇文化传媒有限公司 | Pure traditional Chinese medicine cooling gel sheet for high fever of kids and method for preparing same |
| CN108379511A (en) * | 2018-04-24 | 2018-08-10 | 烟台金蕊女性用品有限公司 | A kind of preparation process of Chinese medicine application cream that alleviating menalgia |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104338050A (en) | Health care product capable of improving sleep quality | |
| CN104147574A (en) | Heat-clearing and exterior-releasing traditional Chinese medicine composition for treating cold and fever and preparation method thereof | |
| CN103610915B (en) | Traditional Chinese medicine for treating swelling and pain in throat | |
| CN104474045A (en) | Traditional Chinese medicine patch for treating febrile convulsion of infants and preparation method of traditional Chinese medicine patch | |
| CN104147460A (en) | Traditional Chinese medicinal preparation for treating Parkinson's disease and preparation method thereof | |
| CN103479968B (en) | Traditional Chinese medicine composition for treating heart-fire flaming acne | |
| CN103845678B (en) | A kind of pharmaceutical composition for treating infant's dermatitis | |
| CN106237039A (en) | A kind of antibacterial cream of rhinitis and preparation method thereof | |
| CN102258602B (en) | Chinese medicinal composition for treating rheumatism and rheumatoid and preparation method thereof | |
| CN104984122A (en) | Chinese herbal medicament for treating tetanus and preparation method thereof | |
| CN106421087A (en) | Pharmaceutical preparation for treating acute eczema, and use of pharmaceutical preparation | |
| CN104523866A (en) | Convulsion and spasm relieving preparation for treating infantile febrile convulsion and preparation method thereof | |
| CN105381064A (en) | Traditional Chinese medicine composition for treating cerebral hemorrhage | |
| CN104906439A (en) | Medicine for treating chronic respiratory failure | |
| CN104491537A (en) | Traditional Chinese medicine composition for treating rheumatic heart disease | |
| CN105233035A (en) | Traditional Chinese medicine preparation for treating epicophosis and preparation method of traditional Chinese medicine preparation | |
| CN104491349A (en) | Medicine for treating convulsions caused by fear and preparation method of medicine | |
| CN104491276A (en) | Traditional Chinese medicine preparation for treating tinnitus and preparation method thereof | |
| CN104162038A (en) | Traditional Chinese medicine composition for treating neonatal seizures and preparation method thereof | |
| CN104383468A (en) | Dizziness relieving and resuscitation inducing preparation for infantile convulsions and preparation method of dizziness relieving and resuscitation inducing preparation | |
| CN103893496A (en) | Traditional Chinese medicine preparation for treating stenocardia and preparation method thereof | |
| CN104189192B (en) | The Traditional Chinese medicine medicated bath for the treatment of urticaria and preparation method | |
| CN104436003A (en) | Traditional Chinese medicine bath for treating urticaria of children and preparation method of traditional Chinese medicine bath | |
| CN102988481A (en) | Traditional Chinese medicine composition for treating rheumatism and rheumatoid | |
| CN103861062A (en) | Traditional Chinese medicine composition for treating rheumatoid diseases and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: Nanping City, Fujian province 353000 Yanping District Industrial Road No. 29 Building No. 3 2-502 Applicant after: Hao Guihua Address before: 250014 Shandong Province, Lixia District of Ji'nan city jiangshuiquan Road No. 1 Applicant before: Hao Guihua |
|
| CB02 | Change of applicant information | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150401 |
|
| WD01 | Invention patent application deemed withdrawn after publication |