CN104306752A - Traditional Chinese medicine for treating liver cirrhosis - Google Patents

Traditional Chinese medicine for treating liver cirrhosis Download PDF

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CN104306752A
CN104306752A CN201410494355.0A CN201410494355A CN104306752A CN 104306752 A CN104306752 A CN 104306752A CN 201410494355 A CN201410494355 A CN 201410494355A CN 104306752 A CN104306752 A CN 104306752A
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chinese medicine
liver cirrhosis
herba
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陈英娣
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Abstract

The invention relates to a traditional Chinese medicine for treating liver cirrhosis. The traditional Chinese medicine for treating liver cirrhosis is prepared by using the following medicinal materials, by weight, 12 parts of Hedyotis caudatifolia, 5 parts of Fructus Tribuli, 8 parts of Semen cassiae sopherae, 5 parts of Spine of Common Jujube, 10 parts of Balanophora involucrata Hook. F., 15 parts of Arthraxon hispidus, 14 parts of Desmos chinensis Lour, 10 parts of Chloranthus japonicus, 10 parts of Cyclosorus acuminatus, 10 parts of Herba Stellariae Saxatilis, 12 parts of Isatis oblongata DC., 14 parts of Thinleaf Mockorange, 10 parts of Mahonia bealei Carr, 8 parts of chrysanthemum sprout, 10 parts of Hypolepis punctata, 12 parts of Woolly Sterculia and 14 parts of Buddleia davidii Franch.. Clinic experiments prove that the liver cirrhosis can be safely and effectively treated by using the traditional Chinese medicine.

Description

A kind of Chinese medicine for the treatment of liver cirrhosis
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of liver cirrhosis.
Background technology
Liver cirrhosis (hepatic cirrhosis) is clinical common chronic progressive external hepatopathy, is that the liver that caused by a variety of causes is chronic, Progressive symmetric erythrokeratodermia, diffuse fibrosis change.In long term morbidity process, liver deforms gradually, and quality is hardening, and hepatocyte is downright bad step by step, and final liver loses function.Histopathology there are hepatic necrosis, the regeneration of remaining liver cell nodules, connective tissue proliferation and fiber widely every formation, cause lobules of liver structural deterioration and pseudolobuli to be formed.Early stage due to the stronger non-evident sympton of liver function metabolism, later stage main manifestations is liver function injury and portal hypertension, and get involved with multisystem, often there is the complication such as upper gastrointestinal hemorrhage, hepatic encephalopathy, secondary infection, hypersplenism, ascites and canceration in late period.This sick prognosis is poor, and the cause of death is often the complication such as hepatic encephalopathy, hepatorenal syndrome, esophageal varices appearance.
Generally acknowledged specific treatment medicine is still lacked at present for liver cirrhosis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Herba Hedyotis Lanceae [source] medical material Ji Yuan: be the herb of dicotyledon medicine Maguireothamnus speciosus Herba Hedyotis Lanceae.Latin plant animal mineral name: Hedyotis lance (Thunb) O.Kuntze [oldenladia lancea (Thunb) O.Kuntze] gathers and stores: summer, autumn gather, and using fresh herb or chopping are dried.[nature and flavor] are sweet; Flat.[return through] lung; Liver; Spleen channel.[function cures mainly] relieving cough and resolving phlegm; Spleen invigorating removing food stagnancy.Main bronchus asthma; Bronchitis; Pulmonary tuberculosis is spat blood; Infantile malnutrition; Traumatic injury; Traumatic hemorrhage.[usage and dosage] takes orally: decoct soup, 9-15g.External: appropriate, smashes and applies or decoct washing.
Flos tribuli [source] medical material Ji Yuan: be the flower of zygophyllaceae plant Fructus Tribuli Tribulus terrestris L..Latin plant animal mineral name: 1.Tribulus terrestris L.2.Tuibulus cistoides L. gathers and stores: the 5-8 month gathers, and dries in the shade or dries.[nature and flavor] are pungent; Temperature.[return through] Liver Channel.[function cures mainly] dispels the wind and blood.Main vitiligo.[usage and dosage] takes orally: grind 3-5g into powder.
Semen Cassiae Sopherae [source] medical material Ji Yuan: be the seed of leguminous plant Cassia sophera.Latin plant animal mineral name: Cassia sophera L. gathers and stores: gather during 10-11 month fruit maturation, cut pod, dry, gets seed and dries for subsequent use.[nature and flavor] sweetness and bitterness; Flat; Nontoxic.[return through] lung; Stomach; Large intestine channel.[function cures mainly] liver heat removing and eyesight improving, during stomach invigorating is adjusted, intestine moistening is detoxified.Main conjunctival congestion and swelling pain, dizzy feeling of fullness in the head, oral erosion, habitual constipation, infantile malnutrition, dysentery, malaria.[usage and dosage] takes orally: decoct soup, 9-15g.
Spina jujubae [source] medical material Ji Yuan: be the Spina jujubae of Rhamnaceae plant Ziziphi Spinosae.Latin plant animal mineral name: Ziziphus jujuba Mill.var.spinosa (Bunge) Hu ex H.F.Chow [Z.vulgaris Lam.var.spinosa Bunge] gathers and stores: all can adopt throughout the year, dry.[nature and flavor] are pungent; Cold.[return through] heart; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Reducing swelling and alleviating pain.Main carbuncle; Sore throat; Hematuria; Stomachache; Lumbago.[usage and dosage] takes orally: decoct soup, 3-6g; Or enter ball, loose.External: appropriate, decocts juice and is coated with; Or grind into powder and store nose.
Herba balanophorae involucratae [source] medical material Ji Yuan: be the herb of Balanophoraceae plant Balanophora involicrata Hook.f..Latin plant animal mineral name: Balanophora involucrata Hook.f. [B.involucrata Hook.f.var.flava Hook.F.] gathers and stores: autumn gathers, removing earth, impurity, dry or using fresh herb.[nature and flavor] are bitter; Puckery; Cold in nature.[return through] lung; Stomach; Liver Channel.[function cures mainly] nourishing the lung to arrest cough; Circulation of qi promoting stomach invigorating; Clearing away heat-damp and promoting diuresis; Cooling blood for hemostasis; The kidney invigorating arresting seminal emission.Main cough due to lung-heat; Epigastric pain, jaundice; Swelling and pain of hemorrhoid; Traumatic injury; Spitting of blood; Menoxenia; Metrorrhagia; Traumatic hemorrhage; Dizzy; Seminal emission.[usage and dosage] takes orally: decoct soup, 9-15g; Or fricassee, infusing drugs in wine.
Herba Arthraxonis Hispidi [source] medical material Ji Yuan: be the herb of grass Herba Arthraxonis Hispidi.Latin plant animal mineral name: Arthraxon hispidus (Thunb.) Makino gathers and stores: the 7-9 month extracts herb, dries.[nature and flavor] are bitter; Flat.[function cures mainly] relieving cough and relieving asthma; Parasite killing detoxifies.Main chronic cough asthma; Hepatitis; Pharyngolaryngitis; Stomatitis; Rhinitis; Lymphadenitis; Mastitis; Skin infection scabies.[usage and dosage] takes orally: decoct soup, 6-15g.External: appropriate, decocts washing or smashes deposited.
Desmos chinensis root [source] medical material Ji Yuan: be the root of annonaceae plant Desmos chinensis.Latin plant animal mineral name: Desmos chinensis Lour. [D.cochinchinensis sensu Merr.] gathers and stores: the whole year all can gather, and section is dried.[nature and flavor] are pungent; Temperature; Slightly poisonous.[return through] liver; Spleen channel.[function cures mainly] wind-expelling pain-stopping; Regulating qi to disperse stagnation; Killing parasites for relieving itching.Main air pain of dampness syndrome; Traumatic injury; The stagnant stomachache of the stasis of blood in puerperal; Dyspepsia; Stomachache abdominal distention; Scabies.[usage and dosage] takes orally: decoct soup, 3-15g; Or infusing drugs in wine.
JIANCAO [source] medical material Ji Yuan: be herb or the root of Chloranthaceae vegetable silk fringe chu lan tree.Latin plant animal mineral name: Chloranthusfortunei (A.Gray) SolmsLamb. gathers and stores: summer gathers, removing impurity, cleans, dries.[nature and flavor] are pungent; Bitter; Flat; Poisonous.[return through] lung; Liver Channel.[function cures mainly] expelling wind and activating blood circulation; Removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome; Traumatic injury; Furuncle tinea scabies; Venom.[usage and dosage] takes orally: decoct soup, root 3-6g.External: fresh herb is appropriate, smashes deposited.
Rhizoma cyclosori acuminati [source] medical material Ji Yuan: be the rhizome on Thelypteridaceae plant Ampelopteris prolifera (Retz.) Copel..Latin plant animal mineral name: Cyclosorus acuminatus (Houtt.) Nakai [polypodium acuminatum Houtt.] gathers and stores: summer, autumn gather, and dry.[nature and flavor] are bitter; Flat.[return through] heart; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Expelling wind and removing dampness; Spleen invigorating.Master has loose bowels; Dysentery; Pyretic stranguria; Laryngopharynx swelling and pain; Rheumatic arthralgia; Infantile malnutrition; Lyssodexis; Burn and scald.[usage and dosage] takes orally: decoct soup, 15-30g, heavy dose of 150-180g.
Raw Herba stellariae mediae Stellaria saxatilis Buch.-Ham. [S.vestita Kurz] of Herba Cucubali [source] Caryophyllaceae Stellaria phytobezoar, with all herbal medicine.Xia Qiucai, cleans and dries or using fresh herb.[nature and flavor] are pungent, cool.Slightly poisonous.[function cures mainly] dampness removing, promoting blood circulation and stopping pain.For icterohepatitis, edema, leucorrhea, traumatic injury, Fengshi Guanjie pain; Fracture is controlled in external, furuncle.[usage and dosage] 1 ~ 3 money.Suitable amount used externally, mashes wine and dresses affected part.
Square leaf Folium Isatidis [source] medical material Ji Yuan: be root and the leaf of Cruciferae Radix Isatidis oblongatae.Latin plant animal mineral name: Isatis oblongaia DC. gathers and stores: summer, autumn gather, and clean, using fresh herb or dry.[nature and flavor] are bitter; Cold.[return through] lung; Large intestine channel.[function cures mainly] relieving sore-throat by clearing away heat; Removing pathogenic heat from blood and toxic substance from the body.Main typhoid fever; Bacillary dysentery puncture; Stomatitis; Pharyngolaryngitis; Tonsillitis; Epistaxis.[usage and dosage] takes orally: decoct soup, 10-15g.
Philadelphus tenuifolius Rupr. Et Maxim [source] medical material Ji Yuan: be the root of saxifragaceae plant Philadelphus tenuifolius Rupr. Et Maxim.Latin plant animal mineral name: Philadelphus tenuifolius Rupr.et Maxim. gathers and stores: summer, autumn excavate root, clean, section is dried.[nature and flavor] are sweet; Flat.[return through] liver; Kidney channel.[function cures mainly] clearing away heat and cooling blood; Diuresis.Main hemorrhoid; Dysuria.[usage and dosage] takes orally: decoct soup, 6-15g.
Fructus Ilicis Cornutae [source] medical material Ji Yuan: be the fruit of holly plant Ilex cornuta Lindl. Ilex cornuta lindl.ex Paxt..Latin plant animal mineral name: Ilex cornuta Lindl.ex Paxt. gathers and stores: winter harvesting ripe fruit, pick fruit stem impurity, dry.[nature and flavor] are bitter; Puckery; Tepor.[return through] liver; Kidney channel.[function cures mainly] invigorating the liver and kidney; Strong muscle is active; The astringent or styptic treatment for spontaneous sweating part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels.Main not empty low grade fever; Bones and muscles pain; Metrorrhagia; Leukorrhagia; Have loose bowels.[usage and dosage] takes orally: decoct soup, 6-10g; Or steep in wine.
Plantula chrysanthemi [source] medical material Ji Yuan: be the young young stem and leaf of feverfew chrysanthemum.Latin plant animal mineral name: Chrysanthemum morifolium (Ra-mat.) Tzvel. gathers and stores: spring or early summer are gathered, and dries in the shade or using fresh herb.[nature and flavor] sweet in the mouth; Micro-hardship; Cool in nature.[function cures mainly] liver heat removing and eyesight improving.Main pass dizziness due to wind pathogen is swooned; Only raw nebula film.[usage and dosage] takes orally: decoct soup, 6-12g.External: appropriate, decocts water smoking and washes.
Hypolepis punctata (Thunb) Mett. [source] medical material Ji Yuan: be the herb of Hypolepis punctata (Thunb) Mett. section plant Hypolepis punctata (Thunb) Mett..Latin plant animal mineral name: Hypolepis punctata (Thunb.) Mett. [Polypodium punctatum Thunb.] gathers and stores: summer, autumn gather, cleans, using fresh herb or dry.[nature and flavor] are bitter; Pungent; Cool.[return through] lung; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Astringing to arrest bleeding.Main burn and scald; Traumatic hemorrhage.[usage and dosage] external: appropriate, fresh grass is smash deposited; Or dry product is ground into powder deposited.
Sterculia pexa pierre [source] medical material Ji Yuan: be the bark of Sterculiaceae plant Sterculia pexa pierre.Latin plant animal mineral name: Sterculia pexa Pierre [S.foetida auct.non L.; S.yunnaensis Hu] to gather and store: the whole year all can adopt.Strip bark, using fresh herb.[nature and flavor] are bitter; Flat.[return through] kidney channel.[function cures mainly] reunion of fractured tendons and bones; Promoting blood circulation and stopping pain.Main injury of tendon and muscle fracture; Treating swelling and pain by traumatic injury.[usage and dosage] external: appropriate, fresh goods is smash deposited; Or grind into powder and dress.
Ramulus et folium buddlejae davidii [source] medical material Ji Yuan: be branch and leaf, the root bark of Buddlejaceae plant Buddleia davidii.Latin plant animal mineral name: [B.Da-vidii Franch.Var.magnifera Rehd.et Wils. gathers and stores Buddleja davidii Franch.: branch and leaf summer, autumn gather, using fresh herb or dry; Root bark spring, autumn excavate, and clean, peeling is dried.[nature and flavor] are pungent; Micro-hardship; Warm in nature; Poisonous.[return through] heart; Liver; Kidney channel.[function cures mainly] expelling wind and cold; Promoting blood circulation and stopping pain; Removing toxic substances parasite killing.Main cough due to wind and cold; Arthralgia pain; Traumatic injury; Carbuncle furuncle; Women's pudendal pruritus; Leprosy; Tinea pedis.[usage and dosage] takes orally: decoct soup, 9 ~ 15g; Or steep in wine.External: appropriate, decocts washing; Or smash deposited.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of liver cirrhosis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing liver cirrhosis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of liver cirrhosis, it is characterized in that, be prepared from by the medical material of following weight proportion: Herba Hedyotis Lanceae 12 parts, Flos tribuli 5 parts, Semen Cassiae Sopherae 8 parts, Spina jujubae 5 parts, Herba balanophorae involucratae 10 parts, Herba Arthraxonis Hispidi 15 parts, Desmos chinensis root 14 parts, JIANCAO 10 parts, Rhizoma cyclosori acuminati 10 parts, Herba Cucubali 10 parts, square leaf Folium Isatidis 12 parts, Philadelphus tenuifolius Rupr. Et Maxim 14 parts, Fructus Ilicis Cornutae 10 parts, Plantula chrysanthemi 8 parts, Hypolepis punctata (Thunb) Mett. 10 parts, Sterculia pexa pierre 12 parts, Ramulus et folium buddlejae davidii 14 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor's in JIUYUE, 2009 collects the out-patient of 90 routine liver cirrhosis altogether between in October ,-2011, wherein man 62 example, female 28 example, age 22-59 year, course of disease 1-7.Be divided at random: treatment group 59 example, blank group 31 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.1 month course for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.1 month course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
According to " Chinese medicine (new drug) guideline of clinical investigations " TCM syndrome the standard of curative effect evaluation that 2002 formulate, effective: tcm clinical practice symptom, sign are obviously improved, disease integration reduces >=70%.Effective: tcm clinical practice symptom, sign all take a favorable turn, disease integration reduces >=30%.Invalid: tcm clinical practice symptom, sign even increase the weight of without improvement, disease integration reduces less than 30%.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group n Effective Effectively Invalid Untoward reaction example Total effective rate (%)
Treatment group 59 12(20.3％) 37(62.7％) 10(17％) 83％ 0
Blank group 31 0 5(16.1％) 26(83.9％) 16.1％ 0
Visible, the medicine that the present invention obtains can safe and effective treatment liver cirrhosis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Herba Hedyotis Lanceae 12 grams, Flos tribuli 5 grams, Semen Cassiae Sopherae 8 grams, Spina jujubae 5 grams, Herba balanophorae involucratae 10 grams, Herba Arthraxonis Hispidi 15 grams, Desmos chinensis root 14 grams, JIANCAO 10 grams, Rhizoma cyclosori acuminati 10 grams, Herba Cucubali 10 grams, square leaf Folium Isatidis 12 grams, Philadelphus tenuifolius Rupr. Et Maxim 14 grams, Fructus Ilicis Cornutae 10 grams, Plantula chrysanthemi 8 grams, Hypolepis punctata (Thunb) Mett. 10 grams, Sterculia pexa pierre 12 grams, Ramulus et folium buddlejae davidii 14 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of liver cirrhosis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: Herba Hedyotis Lanceae 12 grams, Flos tribuli 5 grams, Semen Cassiae Sopherae 8 grams, Spina jujubae 5 grams, Herba balanophorae involucratae 10 grams, Herba Arthraxonis Hispidi 15 grams, Desmos chinensis root 14 grams, JIANCAO 10 grams, Rhizoma cyclosori acuminati 10 grams, Herba Cucubali 10 grams, square leaf Folium Isatidis 12 grams, Philadelphus tenuifolius Rupr. Et Maxim 14 grams, Fructus Ilicis Cornutae 10 grams, Plantula chrysanthemi 8 grams, Hypolepis punctata (Thunb) Mett. 10 grams, Sterculia pexa pierre 12 grams, Ramulus et folium buddlejae davidii 14 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of liver cirrhosis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: Herba Hedyotis Lanceae 12 grams, Flos tribuli 5 grams, Semen Cassiae Sopherae 8 grams, Spina jujubae 5 grams, Herba balanophorae involucratae 10 grams, Herba Arthraxonis Hispidi 15 grams, Desmos chinensis root 14 grams, JIANCAO 10 grams, Rhizoma cyclosori acuminati 10 grams, Herba Cucubali 10 grams, square leaf Folium Isatidis 12 grams, Philadelphus tenuifolius Rupr. Et Maxim 14 grams, Fructus Ilicis Cornutae 10 grams, Plantula chrysanthemi 8 grams, Hypolepis punctata (Thunb) Mett. 10 grams, Sterculia pexa pierre 12 grams, Ramulus et folium buddlejae davidii 14 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of liver cirrhosis.Oral, every bu is taken for twice sooner or later.

Claims (1)

1. treat the Chinese medicine of liver cirrhosis for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Herba Hedyotis Lanceae 12 parts, Flos tribuli 5 parts, Semen Cassiae Sopherae 8 parts, Spina jujubae 5 parts, Herba balanophorae involucratae 10 parts, Herba Arthraxonis Hispidi 15 parts, Desmos chinensis root 14 parts, JIANCAO 10 parts, Rhizoma cyclosori acuminati 10 parts, Herba Cucubali 10 parts, square leaf Folium Isatidis 12 parts, Philadelphus tenuifolius Rupr. Et Maxim 14 parts, Fructus Ilicis Cornutae 10 parts, Plantula chrysanthemi 8 parts, Hypolepis punctata (Thunb) Mett. 10 parts, Sterculia pexa pierre 12 parts, Ramulus et folium buddlejae davidii 14 parts.
CN201410494355.0A 2014-09-24 2014-09-24 Traditional Chinese medicine for treating liver cirrhosis Pending CN104306752A (en)

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CN105079316A (en) * 2015-08-20 2015-11-25 青岛金智高新技术有限公司 Pharmaceutical composition for treating liver cirrhosis and application of pharmaceutical composition

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CN1241416A (en) * 1998-07-11 2000-01-19 王亮 Preparation of medicine for hepatocirrhosis ascites
CN103736036A (en) * 2014-01-28 2014-04-23 张怀胜 Drug for treating nonalcoholic fatty liver disease and preparation method thereof

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* Cited by examiner, † Cited by third party
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CN105079316A (en) * 2015-08-20 2015-11-25 青岛金智高新技术有限公司 Pharmaceutical composition for treating liver cirrhosis and application of pharmaceutical composition

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