CN104645113A - Traditional Chinese medicine preparation for treating nasopharyngeal carcinoma and preparation method of traditional Chinese medicine preparation - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating nasopharyngeal carcinoma. The traditional Chinese medicine preparation is mainly prepared from the following active pharmaceutical ingredients in parts by weight: 10-15 parts of bolbostemma paniculatum, 8-12 parts of purpleflower holly leaves, 9-16 parts of barbed skullcap herb, 7-15 parts of arisaema cum bile, 5-9 parts of manchurian wildginger (added later), 9-16 parts of rhizome of manyleaf paris, 15-30 parts of cassia twigs, 6-9 parts of crinis trachycarpi, 8-16 parts of common selfheal fruit-spike, 8-15 parts of mitten crab carapace, 9-16 parts of cactus, 10-20 parts of lalang grass rhizome, 10-20 parts of radix stephaniae tetrandrae, 9-16 parts of selaginella doederleinii and 10-15 parts of biond magnolia flower. The preparation is summarized from years of clinical practices, the traditional Chinese medicine preparation has the effects of clearing away heat and toxic materials as well as converging and stopping bleeding, the treatment effect is good, and the recurrence rate can be effectively reduced.

Description

A kind of Chinese medicine preparation and method for making for the treatment of nasopharyngeal carcinoma

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine preparation and method for making for the treatment of nasopharyngeal carcinoma.

Background technology

Nasopharyngeal carcinoma is the malignant tumor being primary in mucous membrane of nasopharynx covering epithelium.Be one of common malignant tumor of China, pernicious frequency conversion is high, and Natural Survival time average is 18.7 months, and onset is hidden, is not easily found in early days.China the ground such as Guangdong, Guangxi, Fujian, Hunan be multiple district, man more than female.Age of onset is mostly middle age, also has teenager to suffer from patient.The cause of disease is relevant with ethnic susceptibility (yellow is ill compared with white people many), inherited genetic factors and ebv infection etc., and nasopharyngeal carcinoma grade malignancy is higher, can occur metastasic cervical lymph nodes in early days.Common symptoms is resorption tears blood, tinnitus, auditory dysesthesia, the inaccessible sense of in ear, headache, diplopia, face fiber crops, nasal obstruction metastasic cervical lymph nodes symptom etc.Nasopharyngeal carcinoma is most commonly in nasopharynx top, is secondly sidewall and pharyngeal recess, sometimes can be multiple.Mainly due to change that is spiritual and emotion, feelings will is not relaxed, make internal organs deficient, positive QI-insufficiency, the transition of outside climatic, environment can not be adapted to, or because virus, the suction of smog, diet are uncomfortable, caused by naso-pharynageal disease (comprising the remaining adenosis in nasopharynx position, mucosal erosion, mucosal ulcer, nasopharynx hyperplastic nodule) etc.

Notification number CN 103055155 A(application number 201210573231.2) Chinese patent literature disclose a kind of Chinese medicine for the treatment of nasopharyngeal carcinoma and preparation method thereof, this Chinese medicine has used the raw materials such as Flos Bombacis Malabarici, Flos Magnoliae, Herba Dendrobii, the Radix Angelicae Dahuricae, Radix Ophiopogonis, Rhizoma Pinelliae Preparatum to make, distinctive Chinese crude drug Flos Bombacis Malabarici is principal agent to area, application high risky area of nasopharyngeal carcinoma Guangdong and Guangxi Provinces, economic and practical, easyly be easy to get, link closely pathogenesis.Publication No. CN103845613 A(application number 201210532689.3) Chinese patent literature disclose a kind of Chinese medicine for the treatment of nasopharyngeal carcinoma, it is made up of the component of following weight portion: Herba Solani Nigri 20-40 gram, Radix Sophorae Tonkinensis 15-25 gram, Pseudobulbus Cremastrae Seu Pleiones 15-25 gram, featured Herba Solani Nigri, Radix Sophorae Tonkinensis, Pseudobulbus Cremastrae Seu Pleiones are cleaned and dried, is developed into 100 order fine powders.Notification number CN 103071112 A(application number 201310001820.8) Chinese patent literature disclose a kind of Chinese medicine for the treatment of nasopharyngeal carcinoma, the weight proportion of its each raw material components is: Radix vitis romanetii 8-12, Fructus Aurantii Immaturus 13-17, Fructus Akebiae 28-32, Radix Ginseng 4-15, Rhizoma Gymnadeniae 4-15, Rhizoma Coptidis 13-17, Oletum Trogopterori 8-12, Herba Duchesneae Indicae 28-32, little red Bulbus Allii root 8-12, Rhizoma Chuanxiong 13-17, Rhizoma Sparganii 4-15, Rhizoma Curcumae 13-17, huechys 28-32, Radix Aristolochiae Kaempferi 4-15, Herba Artemisiae Anomalae 8-12, Radix Tinosporae 28-32, Herba Houttuyniae 1-5, Radix seu folium abelmoschi moschati 8-12, Aster oreophilus Franch 4-15, Herba Catharanthi Rosei 1-5, Nidus Vespae 28-32, Herba Polygoni cymosi 13-17.

Treat the conventional method of nasopharyngeal carcinoma now, comprise operative treatment, radiotherapy and chemotherapy, through clinical proof, these means are large to human body side effect, it is high to damage, Chinese medicine can compensate its defect, and eliminates the toxic and side effects of chemicotherapy, therefore can study the Chinese medicine formula of more remarkable treatment effect.

Summary of the invention

For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take wide a kind of Chinese medicine preparation and the method for making for the treatment of nasopharyngeal carcinoma of safe and applicable.

Technical scheme of the present invention is:

Treat a Chinese medicine preparation for nasopharyngeal carcinoma, be prepared from primarily of following bulk drugs, be mass parts: Rhizoma Bolbostematis 10-15; Ilex purpurea Hassk.[I.chinensis Sims 8-12; Herba Scutellariae Barbatae 9-16; Arisaema Cum Bile 7-15; Herba Asari (entering afterwards) 5-9; Rhizoma Paridis 9-16; Ramulus Cinnamomi 15-30; Charred Petiolus Trachycarpi 6-9; Spica Prunellae 8-16; Carapax Eriocheir sinensis 8-15; Caulis Echinopsis Multiplicis 9-16; Rhizoma Imperatae 10-20; Radix Stephaniae Tetrandrae 10-20; Herba Selaginellae Doederleinii 9-16; Flos Magnoliae 10-15.

Preferred scheme is, Rhizoma Bolbostematis 11-14; Ilex purpurea Hassk.[I.chinensis Sims 9-11; Herba Scutellariae Barbatae 11-14; Arisaema Cum Bile 9-13; Herba Asari (entering afterwards) 6-8; Rhizoma Paridis 11-14; Ramulus Cinnamomi 20-25; Charred Petiolus Trachycarpi 7-8; Spica Prunellae 10-14; Carapax Eriocheir sinensis 10-13; Caulis Echinopsis Multiplicis 11-14; Rhizoma Imperatae 12-18; Radix Stephaniae Tetrandrae 13-17; Herba Selaginellae Doederleinii 11-14; Flos Magnoliae 11-14.

What be more preferably is, Rhizoma Bolbostematis 12.5; Ilex purpurea Hassk.[I.chinensis Sims 10; Herba Scutellariae Barbatae 12.5; Arisaema Cum Bile 11; Herba Asari (entering afterwards) 7; Rhizoma Paridis 12.5; Ramulus Cinnamomi 22.5; Charred Petiolus Trachycarpi 7.5; Spica Prunellae 12; Carapax Eriocheir sinensis 11.5; Caulis Echinopsis Multiplicis 12.5; Rhizoma Imperatae 15; Radix Stephaniae Tetrandrae 15; Herba Selaginellae Doederleinii 12.5; Flos Magnoliae 12.5.

Described a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma, be made into pharmaceutically acceptable electuary, its preparation method is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heating 3-9 minute is (preferred: slow fire heats 5-7 minute; Be more preferably: slow fire heats 6 minutes), take out and put into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 20-40 minute (preferably: vinegar water steams 25-35 minute; Be more preferably: vinegar water steams 30 minutes), put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire to boil, filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized, be added to mixing in step (4) gained filtrate, this filtrate of spraying dry, adds pharmaceutical excipients, makes electuary.

Described a kind of preparation method for the treatment of the Chinese medicine preparation electuary of nasopharyngeal carcinoma, step (4) turns little fire and boils 22-34 minute (preferably: turn a little fire and boil 26-30 minute; Be more preferably: turn little fire and boil 28 minutes).

Described a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma, be made into pharmaceutically acceptable syrup, its preparation method is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heating 3-9 minute is (preferred: slow fire heats 5-7 minute; Be more preferably: slow fire heats 6 minutes), take out and put into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 20-40 minute (preferably: vinegar water steams 25-35 minute; Be more preferably: vinegar water steams 30 minutes), put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 20 minutes, filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized, mix with step (4) gained filtrate, heating is concentrated into thick paste, then adds cane sugar powder, stirs and obtains syrup.

Described a kind of preparation method for the treatment of the Chinese medicine preparation syrup of nasopharyngeal carcinoma, the amount of step (5) cane sugar powder is that the 0.4-0.7 of thick paste quality is doubly (preferred: the amount of cane sugar powder is 0.5-0.6 times of thick paste quality; Be more preferably: the amount of cane sugar powder is 0.55 times of thick paste quality).

Described a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma, be made into pharmaceutically acceptable decoction, its preparation method is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heating 3-9 minute is (preferred: slow fire heats 5-7 minute; Be more preferably: slow fire heats 6 minutes), take out and put into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 20-40 minute (preferably: vinegar water steams 25-35 minute; Be more preferably: vinegar water steams 30 minutes), put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continue 10 minutes, then add Herba Asari (entering afterwards), turn little fire and boil 22-34 minute (preferably: turn a little fire and boil 26-30 minute; Be more preferably: turn little fire and boil 28 minutes), filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized and sieved, be added to mixing in step (4) gained filtrate, obtain decoction.

Described a kind of preparation method for the treatment of the Chinese medicine preparation decoction of nasopharyngeal carcinoma, it is (preferred: to pulverize 130-160 mesh sieve that step (5) pulverized 110-180 mesh sieve; Be more preferably: pulverized 145 mesh sieves).

Described a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma, be made into pharmaceutically acceptable tablet, its preparation method is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heating 3-9 minute is (preferred: slow fire heats 5-7 minute; Be more preferably: slow fire heats 6 minutes), take out and put into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 20-40 minute (preferably: vinegar water steams 25-35 minute; Be more preferably: vinegar water steams 30 minutes), put into marmite after taking-up and forge crisp, spray yellow wine, taking-up is dried in the air cool, pulverizes together with step (1) (2) made crude drug;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 20 minutes, filter to get filtrate;

(5) by step (3) and (4) made medicated powder and filtrate mixing, spray granulation, is crushed to tablet dosage form, obtains tablet.

Described a kind of preparation method for the treatment of the Chinese medicine preparation tablet of nasopharyngeal carcinoma, the weight of step (5) tablet is 0.3-0.4g/ grain (preferred: the weight of tablet is 0.35g/ grain).

A kind of formula of Chinese materia medica preparation science for the treatment of nasopharyngeal carcinoma provided by the invention, preparation method is simple.In addition, its excellent part also shows:

1, products obtained therefrom of the present invention, therapeutic effect is good, and total effective rate is high, effectively can reduce relapse rate;

2, this formula is summed up through clinical practice for many years and is formed, and has heat-clearing and toxic substances removing, anastaltic effect;

3, Chinese crude drug selected by the present invention, side effect is little, can long-term taking, can regulate patient body function.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Rhizoma Bolbostematis: base is former: be the dry tuber of cucurbitaceous plant Bolbostemma paniculatum.Chemical analysis: containing maltose in tuber, after drying then containing sucrose, petiole is mainly containing reducing sugar.Leaf is mainly containing sucrose.Nature and flavor: bitter, cool.Gui Jing: return lung, spleen channel.Function cures mainly: eliminating stagnation poison, subduing inflammation.Control acute mastitis, scrofula sucutaneous nodule, sore swollen toxin and snakeworm poison.

Ilex purpurea Hassk.[I.chinensis Sims: base is former: be the leaf of winter plant Ilicis Purpureae.Nature and flavor: bitter; Puckery; Cool.Function cures mainly: heat-clearing and toxic substances removing; Promoting tissue regeneration and ulcer healing; Promoting blood circulation and hemostasis.Main cough due to lung-heat; Laryngopharynx swelling and pain; Dysentery; Diarrhoea; Biliary tract infection; Urinary tract infection; Angina pectoris; Burn and scald; Pyretic toxicity carbuncle; Ulcer of the lower limb; Leprelcosis; Eczema; Chilblain; Chap; Thromboangiitis obliterans; Traumatic hemorrhage.

Herba Scutellariae Barbatae: base is former: be the herb of labiate Herba Scutellariae Barbatae.Chemical analysis: herb is containing alkaloid, flavonoid glycoside, phenols, steroidal.Nature and flavor: pungent are flat.Function cures mainly: heat clearing away, removing toxic substances, dissipating blood stasis, hemostasis, analgesic therapy.Control haematemesis, epistaxis, stranguria with blood, bloody dysentery, jaundice, have sore throat, lung abscess, furuncle, scrofula, sore, cancerous protuberance, traumatic injury knife injury, venom.

Arisaema Cum Bile: base is former: for the fine powder of Rhizoma Arisaematis (processed) and cattle, sheep or Fel Sus domestica process from strand, or form through fermentation processing for Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica.Nature and flavor: bitter, micro-pungent, cool.Gui Jing: return lung, liver, spleen channel.Function cures mainly: removing heat-phlegm, dispelling wind and relieving convulsion.For phlegm-heat cough, cough up phlegm yellow thick, middle wind-phlegm fan, demented infantile convulsion.

Herba Asari: nature and flavor with return through: pungent, temperature.GUIXIN, lung, kidney channel.There is expelling wind and cold, wind-expelling pain-stopping, sensible, effect of warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction watery nasal discharge, allergic rhinitis, nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.

Rhizoma Paridis: base is former: be the rhizome of liliaceous plant Rhizoma Paridis, RHIZOMA PARIDIS and several congeners thereof.Chemical analysis: Rhizoma Paridis root is containing paridin, dioscin, and the 3-glycoside of diosgenin, 3-scillabiose, 3-rhamnose arabinose glycoside and 3-tetra-glucoside, the diene alcohol ketone-3-that is pregnent investigates the multiple Saponins such as solatriose glycoside.Nature and flavor: toil, cold, poisonous.Gui Jing: enter the heart, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, antiasthmatic-antitussive, and relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion.Control carbuncle, furuncle, scrofula, sore throat, chronic tracheitis, infantile convulsion is twitched, snake bite and insect sting.

Ramulus Cinnamomi: nature and flavor with return through acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.Function with cure mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.

Charred Petiolus Trachycarpi: Petiolus Trachycarpi: nature and flavor with return through: bitter, puckery, flat.Return lung, liver, large intestine channel.Function with cure mainly: astringing to arrest bleeding.For spitting blood, epistaxis, hematuria, has blood in stool, metrorrhagia.Charred Petiolus Trachycarpi: get clean Petiolus Trachycarpi, according to the charcoal processing of charcoal (calcined) method, it is irregular bulk, not of uniform size.Surface pitchy is to black, glossy, has vertical vertical bar stricture of vagina; That touches has black powdered carbon.Inner coke yellow, fibroid.Somewhat burnt odor gas, bitter and puckery flavor.

Spica Prunellae: base is former: be the fruit ear of labiate Spica Prunellae.Nature and flavor with return through: pungent, bitter, cold.Return liver, gallbladder meridian.There is purging liver-fire, improving eyesight, effect of mass dissipating and swelling eliminating.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, acute mastitis, nodules of the breast, distending pain of the breast.

Carapax Eriocheir sinensis: base is former: be the carapace of Grapsidae animal Eriocheir sinensis and Eriocheir japonicus (de Haan)．.Nature and flavor: salty in the mouth; Cold in nature.Gui Jing: liver; Spleen channel.Function cures mainly: scattered silt is stopped blooding; Removing toxic substances and promoting subsidence of swelling.Main jaundice due to accumulation of stagnant blood; Hemostagnant metrorrhagia; Carbuncle pyogenic infections from tumour or sore; Acute gangrenous stomatitis; Insect bite.

Caulis Echinopsis Multiplicis: base is former: be the stem of Cactaeous plants Caulis Echinopsis Multiplicis.Nature and flavor: sweet light are flat.Gui Jing: lung; Stomach warp.Function cures mainly: clearing and antitussive; Removing pathogenic heat from blood and toxic substance from the body; Reducing swelling and alleviating pain.Main cough due to lung-heat; Sputum mixed with blood; Epistaxis; Spit blood; Gastric ulcer; Carbuncle; Scald; Snake bite and insect sting.

Rhizoma Imperatae: nature and flavor with return through: sweet, cold.Return lung, stomach, urinary bladder channel.There is cooling blood for hemostasis, effect of clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, jaundice due to damp-heat, edema oliguria, the puckery pain of pyretic stranguria.

Radix Stephaniae Tetrandrae: base is former: be the root of menispermaceous plants Radix stephaniae tetrandrae, Radix cocculi laurifolii and aristolochiaceae plant Radix Aristolochiae Fangchi, radix aristolochiae heterophyllae.Nature and flavor: bitter, cold.Gui Jing: enter bladder, spleen, kidney channel.Function cures mainly: row water, rushes down damp-heat in lower-JIAO.Harness the river swollen tympanites, hygropyretic beriberi, brothers' spasm and pain, tinea scabies swells.

Herba Selaginellae Doederleinii: base is former: be the herb of Spikemoss plant selaginella doederleinii.Chemical analysis: containing hordenine-O-α-L-rhamnopyranosyloxyhy glucoside, N-methyltyramine-O-α-L-rhamnopyranosyloxyhy glucoside, (E)-hordenine-(6-O-cinnamoyl-β-D-glucopyranosyl)-(1 → 3)-α-L-rhamnopyranosyloxyhy glucoside (E)-hordenine-［ 6-O-(4-hydroxycinnamoyl)-β-D-glucopyranosyl ］-(1 → 3)-α-L-rhamnopyranosyloxyhy glucoside.Nature and flavor: sweet; Micro-hardship; Puckery; Cool; Light; Temperature.Function cures mainly: heat-clearing and toxic substances removing; Expelling wind and removing dampness.Main laryngopharynx swelling and pain; Conjunctival congestion and swelling pain; Cough due to lung-heat; Mastitis; Jaundice due to damp-heat; Rheumatic arthralgia; Traumatic hemorrhage.

Flos Magnoliae: base is former: be the alabastrum of Magnoliacea plant Flos Magnoliae or Magnolia denudata.Chemical analysis: Magnolia denudata alabastrum containing volatile oil, in containing citral, eugenol, 1, 8-Cineole.Root is containing magnoflorine.Leaf and fruit all contains the glycoside of peonidin.Nature and flavor: pungent, temperature.Gui Jing: enter lung, stomach warp.Function cures mainly: dispel the wind, sensible.Control headache, nasal sinusitis, have a stuffy nose obstructed, toothache.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.

embodiment 1treat a Chinese medicine preparation for nasopharyngeal carcinoma, be prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Bolbostematis 10 parts, Ilex purpurea Hassk.[I.chinensis Sims 8 parts, Herba Scutellariae Barbatae 9 parts, Arisaema Cum Bile 7 parts, Herba Asari (entering afterwards) 5 parts, Rhizoma Paridis 9 parts, Ramulus Cinnamomi 15 parts, charred Petiolus Trachycarpi 6 parts, Spica Prunellae 8 parts, Carapax Eriocheir sinensis 8 parts, Caulis Echinopsis Multiplicis 9 parts, Rhizoma Imperatae 10 parts, Radix Stephaniae Tetrandrae 10 parts, Herba Selaginellae Doederleinii 9 parts, Flos Magnoliae 10 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine preparation electuary of nasopharyngeal carcinoma is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 15 minutes, taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heats 6 minutes, takes out and puts into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 30 minutes, put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 28 minutes, filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized, be added to mixing in step (4) gained filtrate, this filtrate of spraying dry, adds pharmaceutical excipients, makes electuary.

embodiment 2treat a Chinese medicine preparation for nasopharyngeal carcinoma, be prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Bolbostematis 15 parts, Ilex purpurea Hassk.[I.chinensis Sims 12 parts, Herba Scutellariae Barbatae 16 parts, Arisaema Cum Bile 15 parts, Herba Asari (entering afterwards) 9 parts, Rhizoma Paridis 16 parts, Ramulus Cinnamomi 30 parts, charred Petiolus Trachycarpi 9 parts, Spica Prunellae 16 parts, Carapax Eriocheir sinensis 15 parts, Caulis Echinopsis Multiplicis 16 parts, Rhizoma Imperatae 20 parts, Radix Stephaniae Tetrandrae 20 parts, Herba Selaginellae Doederleinii 16 parts, Flos Magnoliae 15 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine preparation syrup of nasopharyngeal carcinoma is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 15 minutes, taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heats 6 minutes, takes out and puts into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 30 minutes, put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 20 minutes, filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized, mix with step (4) gained filtrate, heating is concentrated into thick paste, then adds the cane sugar powder of thick paste quality 0.55 times, stirs and obtains syrup.

Model case: xxx, male, 41 years old.Main suit: tears blood one week, and nasopharynx goes out to have swollen thing; Medical history: patient occurs resorption tears blood without obvious inducement, without uncomfortable diseases such as nasal obstruction, headache, tinnitus, is just not placed in the heart, rear tears blood obviously increases the weight of, and to examination in hospital, finds that nasopharynx part top visible nodositas swells thing, smooth surface, visible secretions, is diagnosed as nasopharyngeal carcinoma through inspection.

Because being reluctant treatment of having an operation, take this example gained syrup, each 10-15g, warm boiled water, one day twice 25 days is a course for the treatment of, after patient takes a course for the treatment of, tears blood phenomenon alleviates to some extent, after continuing to take two courses for the treatment of, lump fades away, and adheres to again taking a course for the treatment of, lump is all eliminated, stable disease.

embodiment 3treat a Chinese medicine preparation for nasopharyngeal carcinoma, be prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Bolbostematis 11 parts, Ilex purpurea Hassk.[I.chinensis Sims 9 parts, Herba Scutellariae Barbatae 11 parts, Arisaema Cum Bile 9 parts, Herba Asari (entering afterwards) 6 parts, Rhizoma Paridis 11 parts, Ramulus Cinnamomi 20 parts, charred Petiolus Trachycarpi 7 parts, Spica Prunellae 10 parts, Carapax Eriocheir sinensis 10 parts, Caulis Echinopsis Multiplicis 11 parts, Rhizoma Imperatae 12 parts, Radix Stephaniae Tetrandrae 13 parts, Herba Selaginellae Doederleinii 11 parts, Flos Magnoliae 11 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine preparation decoction of nasopharyngeal carcinoma is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 15 minutes, taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heats 6 minutes, takes out and puts into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 30 minutes, put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 28 minutes, filter to get filtrate;

(5) step (1), (2) and (3) made crude drug were pulverized 145 mesh sieves, and be added to mixing in step (4) gained filtrate, obtain decoction.

Model case: xxx, women, 32 years old.Medical history: before patient half a year, finds unintentionally with the blood streak in nasal mucus, and with symptoms such as dizziness, tinnitus, caused by thinking that inflammation gets angry, does not take notice of, afterwards aggravation, removes examination in hospital, through nasopharyngeal endoscope and biopsy, be finally diagnosed as nasopharyngeal carcinoma.

Recommend to take a kind of Chinese medicine preparation decoction for the treatment of nasopharyngeal carcinoma of this example gained through people, each 150-200ml, one day twice 25 days is a course for the treatment of, after patient takes one month, rhinopharyngeal neoplasm starts to reduce, after adhering to taking three months, lump is vanished from sight substantially, without other uncomfortable diseases, follow up a case by regular visits in 1 year, tumor has no transfer and recurrence.

embodiment 4treat a Chinese medicine preparation for nasopharyngeal carcinoma, be prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Bolbostematis 14 parts, Ilex purpurea Hassk.[I.chinensis Sims 11 parts, Herba Scutellariae Barbatae 14 parts, Arisaema Cum Bile 13 parts, Herba Asari (entering afterwards) 8 parts, Rhizoma Paridis 14 parts, Ramulus Cinnamomi 25 parts, charred Petiolus Trachycarpi 8 parts, Spica Prunellae 14 parts, Carapax Eriocheir sinensis 13 parts, Caulis Echinopsis Multiplicis 14 parts, Rhizoma Imperatae 18 parts, Radix Stephaniae Tetrandrae 17 parts, Herba Selaginellae Doederleinii 14 parts, Flos Magnoliae 14 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine preparation tablet of nasopharyngeal carcinoma is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 15 minutes, taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heats 6 minutes, takes out and puts into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 30 minutes, put into marmite and forge crisp after taking-up, spray yellow wine, taking-up is dried in the air cool, pulverizes together with step (1) (2) made crude drug;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 20 minutes, filter to get filtrate;

(5) by step (3) and (4) made medicated powder and filtrate mixing, spray granulation, is crushed to tablet dosage form, obtains tablet (weight is 0.35g/ grain).

Model case: xxx, women, 48 years old.Medical history: patient is diagnosed as the nasopharyngeal carcinoma III phase, it is 3.4mm × 3mm that CT shows tumor size, and after once adopting surgical resection therapy and chemicotherapy, the state of an illness is transferred to thyroid, and cardinal symptom is dry mouth and throat, insomnia tinnitus, dizzy weak etc., and patient suffering can't bear.

People is listened to introduce Chinese traditional treatment effect better, housecoat this example gained tablet, each 3-4 grain, warm boiled water, one day twice 25 days is a course for the treatment of, after patient takes two courses for the treatment of, uncomfortable disease alleviates to some extent, and after continuing to take two courses for the treatment of, tumor starts to reduce, diffusion is controlled, after consolidating again a course for the treatment of, patient experiences stable disease, energy returns to normally substantially.

embodiment 5treat a Chinese medicine preparation for nasopharyngeal carcinoma, be prepared from (every part of 10g) primarily of following bulk drugs: Rhizoma Bolbostematis 12.5 parts, Ilex purpurea Hassk.[I.chinensis Sims 10 parts, Herba Scutellariae Barbatae 12.5 parts, Arisaema Cum Bile 11 parts, Herba Asari (entering afterwards) 7 parts, Rhizoma Paridis 12.5 parts, Ramulus Cinnamomi 22.5 parts, charred Petiolus Trachycarpi 7.5 parts, Spica Prunellae 12 parts, Carapax Eriocheir sinensis 11.5 parts, Caulis Echinopsis Multiplicis 12.5 parts, Rhizoma Imperatae 15 parts, Radix Stephaniae Tetrandrae 15 parts, Herba Selaginellae Doederleinii 12.5 parts, Flos Magnoliae 12.5 parts.Above-mentioned a kind of preparation method for the treatment of the Chinese medicine preparation electuary of nasopharyngeal carcinoma is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 15 minutes, taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heats 6 minutes, takes out and puts into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 30 minutes, put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 28 minutes, filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized, be added to mixing in step (4) gained filtrate, this filtrate of spraying dry, adds pharmaceutical excipients, makes electuary.

test example 1a kind of clinical practice for the treatment of the Chinese medicine preparation (embodiment 5) of nasopharyngeal carcinoma of gained of the present invention:

Choose crowd: in January, 2014 in December ,-2014, according to medical case history, be diagnosed as patient 322 example of nasopharyngeal carcinoma four hospital's screenings, male patient 201 example, female patient 121 example, age 36-58 year, 42.3 ± 1.1 years old mean age, course of disease 0.5-4, wherein I phase patient 89 example, II phase 121 example, III phase 76 example, IV phase 36 example.

Before test, patient is divided into two groups at random, experimental group 200 example and matched group 122 routine, two groups in age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes a kind of Chinese medicine preparation electuary for the treatment of nasopharyngeal carcinoma of gained of the present invention, each 5-10g, one day twice, and warm boiled water 25 days is a course for the treatment of; Matched group adopts the conventional means such as chemicotherapy or operative treatment.Treatments period carries out Continuous Observation to two groups of patients, record change of illness state.

Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: nasopharynx part cancerous protuberance and lymphonodi cervicales disappear, and symptom and sign disappear, and cancerous cell is not found in nasopharynx part biopsy; (2) effective: nasopharynx part cancerous protuberance and lymphonodi cervicales reduce, symptom and sign are improved, and nasopharynx part and lymphonodi cervicales biopsy still can find cancerous cell; (3) invalid: cancerous protuberance has no and reduces, continue to increase and accelerate to adjacent tissue's expansion and distally shift, dead in dyscrasia eventually.

Clinical effectiveness: after the treatment of four courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:

As shown in Table 1, the healing patient of experimental group is 21 examples, and cure rate is 10.5%, effective patient is 172 examples, and effective percentage is 86.0%, and total effective rate is 96.5%, and the patient that matched group is cured is 5 examples, cure rate is 4.1%, and effective patient is 83 examples, effective percentage is 68.0%, total effective rate 72.1%, significantly lower than the therapeutic effect of experimental group, illustrates that products obtained therefrom of the present invention is evident in efficacy, the diffusion of effective suppression nasopharyngeal carcinoma, reduces recurrence probability.

The Chinese medicine used in the present invention, Rhizoma Bolbostematis can removing toxic substances and promoting subsidence of swelling, Ilex purpurea Hassk.[I.chinensis Sims, Rhizoma Paridis and Herba Selaginellae Doederleinii can heat-clearing and toxic substances removing, Herba Scutellariae Barbatae can be stopped blooding analgesic therapy, and Arisaema Cum Bile can removing heat-phlegm, and Herba Asari can wind-expelling pain-stopping, Ramulus Cinnamomi can promoting the flow of QI-blood by warming the meridian, charred Petiolus Trachycarpi can astringing to arrest bleeding, and Spica Prunellae can mass dissipating and swelling eliminating, and Carapax Eriocheir sinensis can removing toxic substances and promoting subsidence of swelling, Caulis Echinopsis Multiplicis can removing pathogenic heat from blood and toxic substance from the body, Rhizoma Imperatae can cooling blood for hemostasis, and under the feasible watery diarrhea of Radix Stephaniae Tetrandrae, Flos Magnoliae can expelling pathogenic wind and restoring the functions of orifices in face, multiple medical material synergism, play effect of heat-clearing and toxic substances removing, astringing to arrest bleeding altogether, effectively suppress the diffusion of nasopharyngeal carcinoma, reduce the misery of patient.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. treat a Chinese medicine preparation for nasopharyngeal carcinoma, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Rhizoma Bolbostematis 10-15; Ilex purpurea Hassk.[I.chinensis Sims 8-12; Herba Scutellariae Barbatae 9-16; Arisaema Cum Bile 7-15; Herba Asari (entering afterwards) 5-9; Rhizoma Paridis 9-16; Ramulus Cinnamomi 15-30; Charred Petiolus Trachycarpi 6-9; Spica Prunellae 8-16; Carapax Eriocheir sinensis 8-15; Caulis Echinopsis Multiplicis 9-16; Rhizoma Imperatae 10-20; Radix Stephaniae Tetrandrae 10-20; Herba Selaginellae Doederleinii 9-16; Flos Magnoliae 10-15.

2. a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma as claimed in claim 1, is characterized in that, Rhizoma Bolbostematis 11-14; Ilex purpurea Hassk.[I.chinensis Sims 9-11; Herba Scutellariae Barbatae 11-14; Arisaema Cum Bile 9-13; Herba Asari (entering afterwards) 6-8; Rhizoma Paridis 11-14; Ramulus Cinnamomi 20-25; Charred Petiolus Trachycarpi 7-8; Spica Prunellae 10-14; Carapax Eriocheir sinensis 10-13; Caulis Echinopsis Multiplicis 11-14; Rhizoma Imperatae 12-18; Radix Stephaniae Tetrandrae 13-17; Herba Selaginellae Doederleinii 11-14; Flos Magnoliae 11-14(is preferably: Rhizoma Bolbostematis 12.5; Ilex purpurea Hassk.[I.chinensis Sims 10; Herba Scutellariae Barbatae 12.5; Arisaema Cum Bile 11; Herba Asari (entering afterwards) 7; Rhizoma Paridis 12.5; Ramulus Cinnamomi 22.5; Charred Petiolus Trachycarpi 7.5; Spica Prunellae 12; Carapax Eriocheir sinensis 11.5; Caulis Echinopsis Multiplicis 12.5; Rhizoma Imperatae 15; Radix Stephaniae Tetrandrae 15; Herba Selaginellae Doederleinii 12.5; Flos Magnoliae 12.5).

3. a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable electuary, its preparation method is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heating 3-9 minute is (preferred: slow fire heats 5-7 minute; Be more preferably: slow fire heats 6 minutes), take out and put into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 20-40 minute (preferably: vinegar water steams 25-35 minute; Be more preferably: vinegar water steams 30 minutes), put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire to boil, filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized, be added to mixing in step (4) gained filtrate, this filtrate of spraying dry, adds pharmaceutical excipients, makes electuary.

4. a kind of preparation method for the treatment of the Chinese medicine preparation electuary of nasopharyngeal carcinoma as claimed in claim 3, is characterized in that, step (4) turn a little fire boil 22-34 minute (preferred: to turn a little fire and boil 26-30 minute; Be more preferably: turn little fire and boil 28 minutes).

5. a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable syrup, its preparation method is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heating 3-9 minute is (preferred: slow fire heats 5-7 minute; Be more preferably: slow fire heats 6 minutes), take out and put into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 20-40 minute (preferably: vinegar water steams 25-35 minute; Be more preferably: vinegar water steams 30 minutes), put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 20 minutes, filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized, mix with step (4) gained filtrate, heating is concentrated into thick paste, then adds cane sugar powder, stirs and obtains syrup.

6. a kind of preparation method for the treatment of the Chinese medicine preparation syrup of nasopharyngeal carcinoma as claimed in claim 5, is characterized in that, the amount of step (5) cane sugar powder be the 0.4-0.7 of thick paste quality doubly (preferred: the amount of cane sugar powder be the 0.5-0.6 of thick paste quality doubly; Be more preferably: the amount of cane sugar powder is 0.55 times of thick paste quality).

7. a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heating 3-9 minute is (preferred: slow fire heats 5-7 minute; Be more preferably: slow fire heats 6 minutes), take out and put into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 20-40 minute (preferably: vinegar water steams 25-35 minute; Be more preferably: vinegar water steams 30 minutes), put into marmite after taking-up and forge crisp, spray yellow wine, take out dry in the air cool, pulverize;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continue 10 minutes, then add Herba Asari (entering afterwards), turn little fire and boil 22-34 minute (preferably: turn a little fire and boil 26-30 minute; Be more preferably: turn little fire and boil 28 minutes), filter to get filtrate;

(5) step (1), (2) and (3) made crude drug are pulverized and sieved, be added to mixing in step (4) gained filtrate, obtain decoction.

8. a kind of preparation method for the treatment of the Chinese medicine preparation decoction of nasopharyngeal carcinoma as claimed in claim 7, is characterized in that, it is (preferred: to pulverize 130-160 mesh sieve that step (5) pulverized 110-180 mesh sieve; Be more preferably: pulverized 145 mesh sieves).

9. a kind of Chinese medicine preparation for the treatment of nasopharyngeal carcinoma as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:

(1) get Ilex purpurea Hassk.[I.chinensis Sims, Herba Scutellariae Barbatae and Herba Selaginellae Doederleinii, remove residual leaf and impurity, be cut into thread, add Sucus Zingberis and infiltrate 10-20 minute (preferably: infiltrate 12-18 minute; Be more preferably: infiltrate 15 minutes), taking-up is dried;

(2) get Ramulus Cinnamomi removing crust, clean and slightly moisten, shred, be placed in parch container, slow fire heating 3-9 minute is (preferred: slow fire heats 5-7 minute; Be more preferably: slow fire heats 6 minutes), take out and put into Sucus Glycyrrhizae immersion, pull oven dry out;

(3) get Carapax Eriocheir sinensis and put into steamer, add vinegar water and steam 20-40 minute (preferably: vinegar water steams 25-35 minute; Be more preferably: vinegar water steams 30 minutes), put into marmite after taking-up and forge crisp, spray yellow wine, taking-up is dried in the air cool, pulverizes together with step (1) (2) made crude drug;

(4) by Rhizoma Bolbostematis, Arisaema Cum Bile, Rhizoma Paridis, charred Petiolus Trachycarpi, Spica Prunellae, Caulis Echinopsis Multiplicis, Rhizoma Imperatae, Radix Stephaniae Tetrandrae and Flos Magnoliae, clean remove impurity, put into marmite, add the soak by water of boiled crude drug quality 7 times, big fire is heated to boiling, continues 10 minutes, then adds Herba Asari (entering afterwards), turn little fire and boil 20 minutes, filter to get filtrate;

(5) by step (3) and (4) made medicated powder and filtrate mixing, spray granulation, is crushed to tablet dosage form, obtains tablet.

10. a kind of preparation method for the treatment of the Chinese medicine preparation tablet of nasopharyngeal carcinoma as claimed in claim 9, is characterized in that, the weight of step (5) tablet is 0.3-0.4g/ grain (preferred: the weight of tablet is 0.35g/ grain).