CN107158282A - A kind of Chinese medicine preparation for treating rhinocarcinoma - Google Patents

A kind of Chinese medicine preparation for treating rhinocarcinoma Download PDF

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Publication number
CN107158282A
CN107158282A CN201710644160.3A CN201710644160A CN107158282A CN 107158282 A CN107158282 A CN 107158282A CN 201710644160 A CN201710644160 A CN 201710644160A CN 107158282 A CN107158282 A CN 107158282A
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rhinocarcinoma
chinese medicine
medicine preparation
bulk drug
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刘建飞
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8984—Dendrobium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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Abstract

The present invention relates to a kind of Chinese medicine preparation for treating rhinocarcinoma, it is made up of the bulk drug of following parts by weight：18 22 parts of selfheal, 18 22 parts of selaginella doederlleini, 18 22 parts of radix semiaquilegiae, 13 17 parts of the radix paeoniae rubrathe, 13 17 parts of the red sage root, 13 17 parts of rhizoma imperatae, 8 12 parts of subprostrate sophora, 8 12 parts of radix pseudostellariae, 8 12 parts of chrysanthemum, 8 12 parts of the flower bud of lily magnolia, 8 12 parts of black nightshade, 37 parts of the stem of noble dendrobium, 37 parts of marine alga, 37 parts of peach kernel, 37 parts of excrementum pteropi, 37 parts of frankincense, 37 parts of myrrh, 37 parts of almond.The present invention has the advantages that evident in efficacy, toxic side effect is small.

Description

A kind of Chinese medicine preparation for treating rhinocarcinoma
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of Chinese medicine preparation for treating rhinocarcinoma.
Background technology
Rhinocarcinoma refers to betide the malignant tumour at the top of nasal cavity with side wall.It is one of China's malignant tumour occurred frequently, the incidence of disease First of ear,nose ＆ throat malignant tumour.Common symptoms are band blood, ear suffocation sense, Hearing, diplopia and head in nasal obstruction, tears Pain etc..The big multipair radiotherapy of rhinocarcinoma has Medium sensitivity, and radiotherapy is the preferred treatment method of rhinocarcinoma.But to higher Break up cancer, the course of disease is later and case of recurrence after radiotherapy, and surgery excision and chemotherapy also belong to indispensable hand Section.
The content of the invention
The technical problem to be solved in the present invention is：To solve the deficiencies in the prior art, nose is treated the invention provides one kind The Chinese medicine preparation of cancer.
A kind of Chinese medicine preparation for treating rhinocarcinoma, is made up of the bulk drug of following parts by weight：18-22 parts of selfheal, selaginella doederlleini 18-22 parts, 18-22 parts of radix semiaquilegiae, 13-17 parts of the radix paeoniae rubrathe, 13-17 parts of the red sage root, 13-17 parts of rhizoma imperatae, 8-12 parts of subprostrate sophora, crown prince 8-12 parts of ginseng, 8-12 parts of chrysanthemum, 8-12 parts of the flower bud of lily magnolia, 8-12 parts of black nightshade, 3-7 parts of the stem of noble dendrobium, 3-7 parts of marine alga, 3-7 parts of peach kernel, five spirits 3-7 parts of fat, 3-7 parts of frankincense, 3-7 parts of myrrh, 3-7 parts of almond.
The Chinese medicine preparation of described treatment rhinocarcinoma, it is preferably, and is made up of the bulk drug of following parts by weight：Selfheal 20 Part, 20 parts of selaginella doederlleini, 20 parts of radix semiaquilegiae, 15 parts of the radix paeoniae rubrathe, 15 parts of the red sage root, 15 parts of rhizoma imperatae, 10 parts of subprostrate sophora, 10 parts of radix pseudostellariae, 10 parts of chrysanthemum, 10 parts of the flower bud of lily magnolia, 10 parts of black nightshade, 5 parts of the stem of noble dendrobium, 5 parts of marine alga, 5 parts of peach kernel, 5 parts of excrementum pteropi, 5 parts of frankincense, 5 parts of myrrh, 5 parts of almond.
The preparation method of the Chinese medicine preparation of described treatment rhinocarcinoma, each bulk drug is weighed according to the parts by weight, will be claimed Taken each bulk drug mixing, sterilization after pack.
Usage and consumption：The Chinese medicine preparation being made plus suitable quantity of water are decocted, are heated to continuing to decoct 15-20 points after boiling point Clock, filters to obtain decoction, is continuously decocted with the method 2 times, merges decoction, is equally divided into 2 parts, patient is early daily, evening respectively takes 1 Part；It is within 30 days a course for the treatment of.
Chinese medicine preparation of the present invention made by above-mentioned each bulk drug and its proportioning, with nourishing Yin and clearing heat, soothing the liver dissipating bind Effect, so as to reach the purpose for the treatment of rhinocarcinoma.
The present invention is had an advantageous effect in that compared with prior art：The present invention has evident in efficacy, toxic side effect small Advantage.
Illustrate beneficial effects of the present invention with reference to clinical trial：
（1）Clinical data：The present invention treats rhinocarcinoma patient 22 altogether, and the age is 39-65 Sui.
（2）Treatment method：The Chinese medicine preparation being made plus suitable quantity of water are decocted, are heated to continuing to decoct 15-20 points after boiling point Clock, filters to obtain decoction, is continuously decocted with the method 2 times, merges decoction, is equally divided into 2 parts, patient is early daily, evening respectively takes 1 Part；It is within 30 days a course for the treatment of.
（3）The standard of curative effect evaluation：
Cure：All targeted sites disappear；
Take a turn for the better：Baseline focus major diameter summation, which reduces, is more than 30%；
It is not cured：Baseline focus major diameter summation reduces not to be occurred up to 30% or new focus.
（4）Treatment results：The present invention treats rhinocarcinoma patient 22 altogether, by the treatment of the 3-5 course for the treatment of, cures 8, accounts for 36%, take a turn for the better 11, account for 50%, not more 3, account for 14%, effective percentage is 86%；Cure in 8,3 courses for the treatment of cure 1,4 courses for the treatment of 4 are cured, 5 courses for the treatment of cure 3.
（5）Model case：
1st, Mr. Li, 41 years old, man suffered from rhinocarcinoma；4 courses for the treatment of of Chinese medicine preparation for taking the present invention are cured, and follow-up is not recurred for 1 year.
2nd, Zhang, 55 years old, man suffered from rhinocarcinoma；5 courses for the treatment of of Chinese medicine preparation for taking the present invention are cured, and are not recurred with 2 years.
Embodiment
Embodiment 1：
A kind of Chinese medicine preparation for treating rhinocarcinoma, is made up of the bulk drug of following parts by weight：20 parts of selfheal, selaginella doederlleini 20 part, day 20 parts of certain herbaceous plants with big flowers, 15 parts of the radix paeoniae rubrathe, 15 parts of the red sage root, 15 parts of rhizoma imperatae, 10 parts of subprostrate sophora, 10 parts of radix pseudostellariae, 10 parts of chrysanthemum, the flower bud of lily magnolia 10 Part, 10 parts of black nightshade, 5 parts of the stem of noble dendrobium, 5 parts of marine alga, 5 parts of peach kernel, 5 parts of excrementum pteropi, 5 parts of frankincense, 5 parts of myrrh, 5 parts of almond.
The preparation method of the Chinese medicine preparation of described treatment rhinocarcinoma, each bulk drug is weighed according to the parts by weight, will be claimed Taken each bulk drug mixing, sterilization after pack.
Embodiment 2：
A kind of Chinese medicine preparation for treating rhinocarcinoma, is made up of the bulk drug of following parts by weight：18 parts of selfheal, selaginella doederlleini 18 part, day 18 parts of certain herbaceous plants with big flowers, 13 parts of the radix paeoniae rubrathe, 13 parts of the red sage root, 13 parts of rhizoma imperatae, 8 parts of subprostrate sophora, 8 parts of radix pseudostellariae, 8 parts of chrysanthemum, 8 parts of the flower bud of lily magnolia, dragon 8 parts of certain herbaceous plants with big flowers, 3 parts of the stem of noble dendrobium, 3 parts of marine alga, 3 parts of peach kernel, 3 parts of excrementum pteropi, 3 parts of frankincense, 3 parts of myrrh, 3 parts of almond.
The preparation method of the Chinese medicine preparation of described treatment rhinocarcinoma, each bulk drug is weighed according to the parts by weight, will be claimed Taken each bulk drug mixing, sterilization after pack.
Embodiment 3：
A kind of Chinese medicine preparation for treating rhinocarcinoma, is made up of the bulk drug of following parts by weight：22 parts of selfheal, selaginella doederlleini 22 part, day 22 parts of certain herbaceous plants with big flowers, 17 parts of the radix paeoniae rubrathe, 17 parts of the red sage root, 17 parts of rhizoma imperatae, 12 parts of subprostrate sophora, 12 parts of radix pseudostellariae, 12 parts of chrysanthemum, the flower bud of lily magnolia 12 Part, 12 parts of black nightshade, 7 parts of the stem of noble dendrobium, 7 parts of marine alga, 7 parts of peach kernel, 7 parts of excrementum pteropi, 7 parts of frankincense, 7 parts of myrrh, 7 parts of almond.
The preparation method of the Chinese medicine preparation of described treatment rhinocarcinoma, each bulk drug is weighed according to the parts by weight, will be claimed Taken each bulk drug mixing, sterilization after pack.

Claims (3)

1. a kind of Chinese medicine preparation for treating rhinocarcinoma, it is characterized in that：It is made up of the bulk drug of following parts by weight：18-22 parts of selfheal, 18-22 parts of selaginella doederlleini, 18-22 parts of radix semiaquilegiae, 13-17 parts of the radix paeoniae rubrathe, 13-17 parts of the red sage root, 13-17 parts of rhizoma imperatae, subprostrate sophora 8-12 Part, 8-12 parts of radix pseudostellariae, 8-12 parts of chrysanthemum, 8-12 parts of the flower bud of lily magnolia, 8-12 parts of black nightshade, 3-7 parts of the stem of noble dendrobium, 3-7 parts of marine alga, peach kernel 3-7 Part, 3-7 parts of excrementum pteropi, 3-7 parts of frankincense, 3-7 parts of myrrh, 3-7 parts of almond.
2. the Chinese medicine preparation for the treatment of rhinocarcinoma according to claim 1, it is characterized in that：By the bulk drug system of following parts by weight Into：20 parts of selfheal, 20 parts of selaginella doederlleini, 20 parts of radix semiaquilegiae, 15 parts of the radix paeoniae rubrathe, 15 parts of the red sage root, 15 parts of rhizoma imperatae, 10 parts of subprostrate sophora, 10 parts of radix pseudostellariae, 10 parts of chrysanthemum, 10 parts of the flower bud of lily magnolia, 10 parts of black nightshade, 5 parts of the stem of noble dendrobium, 5 parts of marine alga, 5 parts of peach kernel, 5 parts of excrementum pteropi, frankincense 5 Part, 5 parts of myrrh, 5 parts of almond.
3. the preparation method of the Chinese medicine preparation for the treatment of rhinocarcinoma according to claim 1 or 2, it is characterized in that：According to described heavy Amount number weighs each bulk drug, will be packed after each bulk drug weighed mixing, sterilization.
CN201710644160.3A 2017-08-01 2017-08-01 A kind of Chinese medicine preparation for treating rhinocarcinoma Withdrawn CN107158282A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173748A (en) * 2014-09-06 2014-12-03 成都市飞龙水处理技术研究所 Orally taken medicine for treating cancer of pharynx and preparation method thereof
CN104645113A (en) * 2015-03-11 2015-05-27 王立湖 Traditional Chinese medicine preparation for treating nasopharyngeal carcinoma and preparation method of traditional Chinese medicine preparation
CN104740061A (en) * 2015-03-09 2015-07-01 陆莎 Traditional Chinese medicine composition for treating nasopharyngeal carcinoma
CN105664016A (en) * 2016-01-26 2016-06-15 青岛华之草医药科技有限公司 Traditional Chinese medicine preparation for treating nasopharyngeal carcinoma

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173748A (en) * 2014-09-06 2014-12-03 成都市飞龙水处理技术研究所 Orally taken medicine for treating cancer of pharynx and preparation method thereof
CN104740061A (en) * 2015-03-09 2015-07-01 陆莎 Traditional Chinese medicine composition for treating nasopharyngeal carcinoma
CN104645113A (en) * 2015-03-11 2015-05-27 王立湖 Traditional Chinese medicine preparation for treating nasopharyngeal carcinoma and preparation method of traditional Chinese medicine preparation
CN105664016A (en) * 2016-01-26 2016-06-15 青岛华之草医药科技有限公司 Traditional Chinese medicine preparation for treating nasopharyngeal carcinoma

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Title
周维顺等: "略论鼻咽癌的诊治原则", 《浙江中医学院学报》 *
李和根: "鼻咽癌治验1例", 《上海中医药杂志》 *
李连华等: "益气养阴汤配合放射治疗鼻咽癌患者远期疗效观察", 《中医杂志》 *
赵建成等: "《肿瘤方剂大辞典》", 30 April 2009, 中医古籍出版社 *
赵智强等: "《恶性肿瘤中医辨治与案例》", 31 January 2015, 中国中医药出版社 *

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