CN104666882A - Traditional Chinese medicine granules for treating chronic bronchitis and preparation method of traditional Chinese medicine granules - Google Patents

Abstract

The invention discloses traditional Chinese medicine granules for treating chronic bronchitis. The traditional Chinese medicine granules are prepared from the following main raw materials in parts by weight: 5-15 parts of tangerine peel, 8-17 parts of liquorice root, 6-12 parts of unibract fritillary bulb, 5-15 parts of indigowoad root, 6-10 parts of platycodon root, 5-15 parts of Mongolian dandelion herb, 10-14 parts of coptis chinensis franch, 7-13 parts of common selfheal fruit-spike, 8-14 parts of ephedra herb, 3-9 parts of dwarf lilyturf tuber, 4-11 parts of Indian buead, 9-16 parts of common goldenrop, 3-8 parts of water chestnuts, 8-15 parts of Ningpo yam rhizome, 2-4 parts of stachys geobombycis, 6-8 parts of common dysosmatis rhizome and root, 5-7 parts of gerbera anandria and 15-18 parts of honeysuckle flower. The traditional Chinese medicine granules have significant effects for chronic bronchitis, have the effects of reducing phlegm and relieving cough, and can further radically cure the symptoms of chronic bronchitis and recuperate a patient with listlessness and fatigue expression caused by a stubborn disease. The traditional Chinese medicine granules disclosed by the invention are mainly prepared by selecting local common medicinal materials, the price is low, and thus the economic burden on the patient is reduced.

Description

A kind of Chinese medicine granules for the treatment of chronic bronchitis and preparation method thereof

Technical field

The invention discloses a kind of Chinese medicine granules, especially Chinese medicine granules for the treatment of chronic bronchitis and preparation method thereof.Belong to traditional Chinese medicine field.

Background technology

Bronchitis refers to the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa and surrounding tissue thereof.Clinically with chronic cough, expectoration or with pant and recurrent exerbation for feature.Chronic bronchitis and acute bronchitis are distinguished comparatively easy, can differentiate: 1. medical history according to following three aspects: acute bronchitis generally at premorbid without bronchitic medical history, namely without chronic cough, expectoration and the medical history such as to pant.And chronic bronchitis previously all has above-mentioned respiratory tract medical history.2. the course of disease and symptom: acute bronchitis onset is very fast, starts, for dry cough, to cough sticky expectorant or purulent sputum later.Vexed swollen or pain after normal companion's breastbone. the General Symptomies such as heating many in 3 ~ 5 days take a turn for the better, but cough, expectoration symptom often continue 2 ~ 3 weeks just recovery.The cough that chronic bronchitis then increases the weight of with for a long time, repeatedly and is gradually outstanding symptom, with expectoration.Expectoration symptom with whether infect relevant, time light time heavy.Also can with panting, the course of disease is delayed.3. complication: acute bronchitis is many without obstructive emphysema and pulmonary heart disease, and chronic bronchitis develops into certain phase all with above-mentioned disease.Chronic bronchitis is the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa caused by Different types of etiopathogenises and surrounding tissue thereof.The most onset of chronic bronchitis is very hidden, start symptom there is no except tussiculaing special, therefore not easily note by patient.First have acute upper respiratory tract infection before some patients onset as acute pharyngolaryngitis, the medical histories such as flu, acute bronchitis, and originally many namely later symptom continues, recurrent exerbation in morbidity cold season, suffer from cold, smoking and flu often make primary disease bring out or increase the weight of.The average prevalence of primary disease China is 3.82%, along with the increase sickness rate at age also increases.The north, mountain area, plateau, cold district and factories and miness, rural area sickness rate are high.Obstructive emphysema and chronic pulmonary heart disease can be developed into.The diagnosis basis of chronic bronchitis is: chronic cough, expectoration or pant lasting more than 2 years, continues more than 3 months every year, and gets rid of other heart and lung diseases person.

The clinical manifestation of chronic bronchitis is: 1. cough: the cough increased the weight of for a long time, repeatedly, is gradually the outstanding behaviours of primary disease.The lighter is only in winter-spring season morbidity, and especially the most obvious with front and back of getting up early morning, daytime, cough was less.Summer and autumn, cough alleviates or disappears.Patient with severe symptoms then all cough by the four seasons, and Winter-Spring is aggravated, and day and night coughs, sooner or later particularly violent.2. expectoration: general expectorant is white slimy cystose, and morning rises more, often not easily brings up because of thickness.Infection or after catching cold symptom aggravate rapidly, amount of expectoration increases, and viscosity increases, or in yellow purulent sputum or with panting.Accidental cause play is coughed and sputum mixed with blood.3. pant: when merging respiratory tract infection, due to mucous membrane of bronchiole congestion and edema, sputum blocks and bronchus luminal stenosis, can produce asthma (panting) symptom.Patient's bottleneck throat to be stridulated sound when breathing, and has wheezing sound during auscultation of lung.Thisly be referred to as asthmatic bronchitis clinically to pant for the type of outstanding behaviours, but its outbreak situation is again unlike typical bronchial asthma.4., easily there is respiratory tract infection repeatedly in repeated infection: when cold season or temperature cataclysm.Now patient's asthma increases the weight of, amount of expectoration showed increased and in purulence, with malaise, and fear of cold, heating etc.There is moist sound in pulmonary, numeration of leukocyte of having a blood test increase etc.Respiratory tract infection repeatedly especially easily makes elderly patients, and sb.'s illness took a turn for the worse, must give pay abundant attention.

Authorization Notice No. CN 102688376 B(application number 201210183884.X in existing patent) patent discloses a kind of Chinese medicine composition for the treatment of chronic bronchitis, it is characterized in that, be made up of the raw material of following weight: Herba Houttuyniae 20 grams, Bulbus Fritillariae Cirrhosae 8 grams, Radix Platycodonis 8 grams, Cortex Mori 10 grams, 10 grams, Poria, Radix Asteris 10 grams, Rhizoma Cynanchi Stauntonii 10 grams, 10 grams, Semen Armeniacae Amarum

Bulbus Lilii 10 grams, Pericarpium Citri Reticulatae 6 grams, Radix Scutellariae 15 grams, Pumex 15 grams, Gecko 15 grams, 6 grams, Radix Glycyrrhizae.Authorization Notice No. CN 102641374 B(application number 201210144181.6) patent discloses a kind of Chinese medicine decoction for the treatment of chronic bronchitis, it is characterized in that this Chinese medicine decoction is made up of the Chinese medicine of following weight portion: Herba Anaphalidis 10-13 part, Herba asclepiadis curassaevicae 10-12 part, Cortex Phellodendri 12-15 part, Herba Houttuyniae 10-13 part, Cortex Moutan 7-9 part, Fructus Citri 4-6 part, Radix Glycyrrhizae 6-8 part, Radix Salviae Miltiorrhizae 9-11 part, Radix Peucedani 8-10 part, Cortex Mori 7-10 part, Calculus Bovis 3-5 part, Rhizoma Atractylodis Macrocephalae 11-13 part, Radix Glehniae 9-11 part.The medicament composing prescription of above-mentioned treatment chronic bronchitis is simple, and effect is single, can only cough-relieving, and treatment chronic bronchitis that can not be real.

Summary of the invention

For the present situation of existing treatment chronic bronchitis curative effect deficiency, an object of the present invention is to provide a kind of Chinese medicine granules for the treatment of chronic bronchitis, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.

Above-mentioned purpose of the present invention is achieved through the following technical solutions:

Treat a Chinese medicine granules for chronic bronchitis, take off the primary raw material stating weight proportion and be prepared from: Pericarpium Citri Reticulatae 5-15 part, Radix Glycyrrhizae 8-17 part, Bulbus Fritillariae Cirrhosae 6-12 part, Radix Isatidis 5-15 part, Radix Platycodonis 6-10 part, Herba Taraxaci 5-15 part, Rhizoma Coptidis 10-14 part, Spica Prunellae 7-13 part, Herba Ephedrae 8-14 part, Radix Ophiopogonis 3-9 part, Poria 4-11 part, Herba Solidaginis 9-16 part, Corm Eleocharitis 3-8 part, Rhizoma Dioscoreae Nipponicae 8-15 part, Stachys geobombycis C. Y. Wu 2-4 part, Radix et Rhizoma Dysosmatis 6-8 part, Herba Leibnitziae 5-7 part, Flos Lonicerae 15-18 part.

A kind of Chinese medicine granules for the treatment of chronic bronchitis, the scheme be more preferably, takes off the primary raw material stating weight proportion and is prepared from: Pericarpium Citri Reticulatae 8-13 part, Radix Glycyrrhizae 12-14 part, Bulbus Fritillariae Cirrhosae 8-10 part, Radix Isatidis 8-13 part, Radix Platycodonis 7-9 part, Herba Taraxaci 8-13 part, Rhizoma Coptidis 11-13 part, Spica Prunellae 9-11 part, Herba Ephedrae 10-12 part, Radix Ophiopogonis 5-7 part, Poria 6-9 part, Herba Solidaginis 11-15 part, Corm Eleocharitis 4-7 part, Rhizoma Dioscoreae Nipponicae 10-13 part, Stachys geobombycis C. Y. Wu 2.5-3.5 part, Radix et Rhizoma Dysosmatis 6.5-7.5 part, Herba Leibnitziae 5.5-6.5 part, Flos Lonicerae 16-17 part.

Treat a Chinese medicine granules for chronic bronchitis, best scheme, takes off the primary raw material stating weight proportion and is prepared from: Pericarpium Citri Reticulatae 11 parts, 13 parts, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae 9 parts, Radix Isatidis 12 parts, Radix Platycodonis 8 parts, Herba Taraxaci 11.5 parts, Rhizoma Coptidis 12 parts, Spica Prunellae 10 parts, 11 parts, Herba Ephedrae, Radix Ophiopogonis 6 parts, 7.5 parts, Poria, Herba Solidaginis 13 parts, Corm Eleocharitis 5 parts, Rhizoma Dioscoreae Nipponicae 11.5 parts, Stachys geobombycis C. Y. Wu 3 parts, Radix et Rhizoma Dysosmatis 7 parts, Herba Leibnitziae 6 parts, Flos Lonicerae 16.5 parts.

The preparation process of above-mentioned Chinese medicine granules is as follows:

1. get Stachys geobombycis C. Y. Wu to clean, drain away the water, get Stachys geobombycis C. Y. Wu weight 1-3 edible oil doubly, put into the hot pot dryouied, drop into Stachys geobombycis C. Y. Wu, frying 3-7 minute when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;

2. Pericarpium Citri Reticulatae, Radix Glycyrrhizae and Radix Platycodonis are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 80-120 mesh sieve stand-by;

3. Bulbus Fritillariae Cirrhosae, Radix Isatidis, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, and slightly stewing 5-15 hour, takes out and drain yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;

4. Spica Prunellae, Herba Ephedrae, Radix Ophiopogonis, Poria, Herba Solidaginis, Corm Eleocharitis, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 20-40 minute, cover lid, at decoction 5-15 minute, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 4-8 days in the sunlight, dries 10-20 minute slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;

5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Thick paste is dried 1-2 hour, obtains drying object, dry at temperature is 60-80 DEG C, pack.

The preparation method of above-mentioned Chinese medicine granules, 1. step gets Stachys geobombycis C. Y. Wu weight 1.5-2.5 edible oil doubly (preferred, to get the edible oil of Stachys geobombycis C. Y. Wu weight 2 times).

The preparation method of above-mentioned Chinese medicine granules, step 2. fine powder crosses 90-110 mesh sieve (preferred, fine powder, crosses 100 mesh sieves).

The preparation method of above-mentioned Chinese medicine granules, step is slightly stewing 8-13 hour 3., takes out and drains yellow wine (preferred, slightly stewing 10 hours, to take out and drain yellow wine).

The preparation method of above-mentioned Chinese medicine granules, 4. step decocts with water to boiling, turns slow fire boiling 25-35 minute (preferred, to decoct with water to boiling, turn slow fire boiling 30 minutes).

The preparation method of above-mentioned Chinese medicine granules, step 4. filtering residue is exposed to the sun 5-7 days in the sunlight, dries slowly 13-18 minute (preferred, filtering residue is exposed to the sun 6 days in the sunlight, be placed in little fire on iron plate dry 15 minutes slowly) being placed in little fire on iron plate.

The preparation method of above-mentioned Chinese medicine granules, 5. thick paste is dried 1.3-1.8 hour by step, obtains drying object, dry at temperature is 65-75 DEG C (preferred, thick paste is dried 1.5 hours, obtain drying object, dry at temperature is 70 DEG C).

Using method: for making Chinese medicine granules of the present invention reach optimum therapeuticing effect, every day twice, half an hour after meal morning and evening, getting 5-10g, take after mixing it with hot water, 10 days is a course for the treatment of.

This Chinese medicine granules, to chronic bronchitis Be very effective, not only has effect of preventing phlegm from forming and stopping coughing, can also effect a radical cure the disease of chronic bronchitis, cause lethargy for prolonged illness, and look tired person has good medical treatment effect.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.

The pharmacological effect of each crude drug is respectively:

Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Gui Jing returns lung, spleen channel.Effect regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly for distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.

Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Function of relieving cough and calming asthma enoxolone has obvious central antitussive effect, and heavy dose of enoxolone can make mouse breathing suppress.In addition glycyrrhizin, glycyrrhetate still have anti-inflammatory and antiallergic, anti-liver injury, anti-promoting, antibacterial, anti AIDS virus (glycyrrhizin) effect.

Bulbus Fritillariae Cirrhosae: nature and flavor bitter in the mouth, sweet, cold nature.Gui Jing returns lung, heart channel.Effect clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, eliminating stagnation eliminating carbuncle.Cure mainly for lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum mixed with blood, scrofula, acute mastitis, lung abscess.

Radix Isatidis: nature and flavor are bitter, cold.Return through GUIXIN, stomach warp.Effect heat-clearing and toxic substances removing, removing heat from blood, sore-throat relieving.Cure mainly pestilence seasonal noxious pathogen, heating pharyngalgia, maculae caused by violent heat pathogen, mumps, scarlet fever, major part pestilence, erysipelas, carbuncle.

Radix Platycodonis: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.

Herba Taraxaci: containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin in Herba Taraxaci plant.Nature and flavor are sweet, micro-hardship, cold.Return liver, stomach warp.There are the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Control pyretic toxicity, carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection etc.Herba Taraxaci is raw-eaten, stir-fry and eat, cook soup, is the plant of dietotherapeutic.

Rhizoma Coptidis: nature and flavor bitter in the mouth, cold in nature.Return through GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Effect heat clearing and damp drying, eliminating fire and detoxication.Cure mainly damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, and carbuncle treats skin ulcer; External treatment eczema, eczema, auditory meatus is suppurated.

Spica Prunellae: acrid in the mouth, hardship, cold.Gui Jing returns liver, gallbladder meridian.Effect purging liver-fire, improving eyesight, mass dissipating and swelling eliminating.

Cure mainly for conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, acute mastitis, nodules of the breast, distending pain of the breast.

Herba Ephedrae: it is warm in nature, acrid in the mouth, micro-hardship, have effect of diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema, can treat anemofrigid cold, the diseases such as edema due to wind pathogen edema, bronchial asthma of breathing with cough uncomfortable in chest.

Radix Ophiopogonis: sweet, micro-hardship, is slightly cold.GUIXIN, lung, stomach warp.YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.

Poria: nature and flavor sweet in the mouth, light, property is put down.Return through GUIXIN, lung, spleen, kidney channel.Effect promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.Cure mainly for edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.

Herba Solidaginis: base is former: be herb or the root of Compositae Herba Solidaginis platymiscium Herba Solidaginis.Composition: aerial parts is containing saponin component: Herba Solidaginis glycosides, activities of Solidago virgaurea L saponin 3 that is 3, Solidago saponin, solidago canadesis saponin, huge Herba Solidaginis saponin, the triterpene glycosides etc. of Polygalacic acid.The property of medicine: pungent, bitter, cool.Function cures mainly: wind and heat dispersing, removing toxic substances and promoting subsidence of swelling.Cure mainly anemopyretic cold, laryngopharynx swelling and pain, cough due to lung-heat, jaundice, pyretic stranguria, carbuncle furuncle, venom, traumatic injury.

Corm Eleocharitis: another name Horse hoof, black taro, Di Li.Flavor efficacy: sweet, cold.Function heat clearing away, reduce phlegm, removing food stagnancy, change wart.Be applicable to that epidemic febrile disease is quenched one's thirst, jaundice, pyretic stranguria, mass in the abdomen, conjunctival congestion, laryngopharynx swelling and pain, wart etc.Prevention acute infectious disease, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, diuresis relieving constipation is eliminated the phlegm, help digestion de-swelling, conditioning hemorrhoid or dysentery is had blood in stool, woman uterine bleeding, lung-dryness syndrome due to deficiency of YIN, phlegm-heat cough, discomfort in the throat, mass in the abdomen are gathered, conjunctival congestion is hidden from view, auxiliary effect such as to bring down a fever.In addition, Corm Eleocharitis contains a kind of antiviral substance can suppress epidemic encephalitis, influenza virus, can be used for the propagation preventing epidemic encephalitis and influenza.

Rhizoma Dioscoreae Nipponicae: another name Dioscorea nipponica Mak. Ningpo Yam Rhizome, Rhizoma Dioscoreae Nipponicae, Dioscorea nipponica bone, ground joist, Rhizoma Smilacis Bockii, chicken bone, mountain Radix Dichroae, Radix Dichroae, parthenocissus, tip of a whip dish.Flavor efficacy is bitter, flat.Return liver, lung meridian.Function relaxing muscles and tendons to promote blood circulation, timid wind pain relieving, relieving cough and asthma, timid expectorant.Be applicable to lumbago and skelalgia, muscles and bones numbness, traumatic injury, lumbar sprain and QI divergeny, cough pant.

Stachys geobombycis C. Y. Wu: call native Cordyceps, white Cordyceps, tapeworm is careless, pulmonary tuberculosis is careless.Flavor efficacy is sweet, flat.The lung moistening of function kidney tonifying, nourishing YIN and supplementing blood, clearing heat and relieving fidgetness.Be applicable to pulmonary tuberculosis cough, deficiency of the lung asthma, haematemesis, night sweat, anemia, infantile malnutrition.

Radix et Rhizoma Dysosmatis: base is former: be the root and rhizome of Berberidaceae Dysosma plant Radix et Rhizoma Dysosmatis, Dysosma Pleiantha and dysosma veitchii Fu.Composition: 1. Radix et Rhizoma Dysosmatis rhizome is containing lignanoid: podophyllotoxin, picropodophyllin; Flavonoid: diphyllin kaempferol, Quercetin etc.2. Dysosma Pleiantha rhizome is containing lignanoid: podophyllotoxin, dehydropodophyllotoxin, podophyllotoxone etc.3. dysosma veitchii Fu root is containing deoxypodophyllotoxin ,-peltain, podophyllotoxin, kaempferol-3--D-Glucose glycosides, glucose, sucrose and-sitosterol.The property of medicine: bitter, pungent, temperature.Poisonous.Return lung, Liver Channel.Function cures mainly: removing toxic substances of reducing phlegm, eliminating stasis and resolving masses.Cure mainly cough, laryngopharynx swelling and pain, scrofula, goiter, nameless gall, herpes zoster, venom, traumatic injury, rheumatic arthralgia.

Herba Leibnitziae: having another name called and burn golden grass, little fire weed, shank grass, is the herb of Compositae Gerbera plant Herba Leibnitziae.The property of medicine: this product is crispaturaed agglomerating, in withered green, rhizome is short, and lower raw most thin fibrous root, achene spindle, two ends are shunk, feeble QI, and bitter in the mouth is cold in nature.Composition: aerial parts, containing coumarin kind compound, contains Virginia prune glucoside again, nail-like boil glycosides.Find according to modern pharmacological research, this medical instrument has antibacterial, clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling effect, for cough due to lung-heat, and damp-heat dysentery, pyretic stranguria, rheumatic arthritis etc.

Flos Lonicerae: its effect mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, stronger restraint is had to the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc., in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, can be used for the treatment of respiratory tract infection, bacillary dysentery, acute urinary, hypertension etc. more than 40 with other medicines compatibility and plant disease.Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.

Chinese medicine granules of the present invention is based on the principle of traditional Chinese medical herbal treatment chronic bronchitis.The medical material selected all has effect of relieving cough and resolving phlegm, for chronic bronchitis determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, belongs to the prescription for the treatment of both the principal and secondary aspects of a disease.Fabulous therapeutical effect is had to chronic bronchitis.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.

embodiment 1: a kind of Chinese medicine granules for the treatment of chronic bronchitis, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Pericarpium Citri Reticulatae 5 parts, 8 parts, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae 6 parts, Radix Isatidis 5 parts, Radix Platycodonis 6 parts, Herba Taraxaci 5 parts, Rhizoma Coptidis 10 parts, Spica Prunellae 7 parts, 8 parts, Herba Ephedrae, Radix Ophiopogonis 3 parts, 4 parts, Poria, Herba Solidaginis 9 parts, Corm Eleocharitis 3 parts, Rhizoma Dioscoreae Nipponicae 8 parts, Stachys geobombycis C. Y. Wu 2 parts, Radix et Rhizoma Dysosmatis 6 parts, Herba Leibnitziae 5 parts, Flos Lonicerae 15 parts.

The preparation method of the Chinese medicine granules of above-mentioned treatment chronic bronchitis, step is as follows:

1. get Stachys geobombycis C. Y. Wu to clean, drain away the water, get the edible oil of Stachys geobombycis C. Y. Wu weight 1 times, put into the hot pot dryouied, drop into Stachys geobombycis C. Y. Wu, frying 3 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;

2. Pericarpium Citri Reticulatae, Radix Glycyrrhizae and Radix Platycodonis are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 80 mesh sieves stand-by;

3. Bulbus Fritillariae Cirrhosae, Radix Isatidis, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 5 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;

4. Spica Prunellae, Herba Ephedrae, Radix Ophiopogonis, Poria, Herba Solidaginis, Corm Eleocharitis, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 20 minutes, cover lid, decoction 5 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 4 days in the sunlight, dries 10-minute slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;

5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Thick paste is dried 1 hour, obtain drying object, dry at temperature is 60 DEG C, pack.

model case one:liu XX, man, 41 years old, people from Jiyang County, Jinan City, Shandong Province.Symptom: patient started the symptom occurring that cough is more than after certain cold, fever before 1 year, patient did not take notice of at that time, but hereafter whenever winter-spring season is often coughed, coughed white foam expectorant, sometimes be purulent sputum, repeatedly increasing the weight of, is chronic bronchitis through hospital diagnosis, in many ways seeks medical advice and all cannot effect a radical cure.See Chinese medicine granules of the present invention once in a while on TV, just buy 1 course for the treatment of.

Take embodiment 1 gained Chinese medicine granules, every day twice, half an hour after meal morning and evening, get 5g, take after mixing it with hot water, use 3 days, cough symptom obviously alleviates; Continue to take 5 days, excessive phlegm symptom alleviates; Take 10 days, rarely found expectorant disease during cough; Use 15 days, every malaise symptoms disappears, and recover, have no side effect during taking Chinese medicine granules of the present invention appearance.

embodiment 2: a kind of Chinese medicine granules for the treatment of chronic bronchitis, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Pericarpium Citri Reticulatae 15 parts, 17 parts, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae 12 parts, Radix Isatidis 15 parts, Radix Platycodonis 10 parts, Herba Taraxaci 15 parts, Rhizoma Coptidis 14 parts, Spica Prunellae 13 parts, 14 parts, Herba Ephedrae, Radix Ophiopogonis 9 parts, 11 parts, Poria, Herba Solidaginis 16 parts, Corm Eleocharitis 8 parts, Rhizoma Dioscoreae Nipponicae 15 parts, Stachys geobombycis C. Y. Wu 4 parts, Radix et Rhizoma Dysosmatis 8 parts, Herba Leibnitziae 7 parts, Flos Lonicerae 18 parts.

The preparation method of the Chinese medicine granules of above-mentioned treatment chronic bronchitis, step is as follows:

1. get Stachys geobombycis C. Y. Wu to clean, drain away the water, get the edible oil of Stachys geobombycis C. Y. Wu weight 3 times, put into the hot pot dryouied, drop into Stachys geobombycis C. Y. Wu, frying 7 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;

2. Pericarpium Citri Reticulatae, Radix Glycyrrhizae and Radix Platycodonis are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 120 mesh sieves stand-by;

3. Bulbus Fritillariae Cirrhosae, Radix Isatidis, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 15 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;

4. Spica Prunellae, Herba Ephedrae, Radix Ophiopogonis, Poria, Herba Solidaginis, Corm Eleocharitis, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 40 minutes, cover lid, decoction 15 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 8 days in the sunlight, dries 20 minutes slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;

5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Thick paste is dried 2 hours, obtain drying object, dry at temperature is 80 DEG C, pack.

model case two:woods XX, man, 48 years old, Shandong Province Qihe people, does manual work in other places for a long time, often gives people's cleaning, catch a cold when adding again patient children, obtained chronic bronchitis, radical cure of having no idea of in many ways seeking medical advice, cough is more than all day, also with asthma when to autumn, sky cyclostrophic is cool, and yellowish green thick sputum, eat antibiotic medicine, develop immunity to drugs in amoxicillin, when flu, also can be dizzy, there is distending pain sense in nasal cavity.

Take embodiment 2 gained Chinese medicine granules, every day twice, half an hour after meal morning and evening, get 8g, take after mixing it with hot water, use 5 days, during cough, thick sputum reduces; Take 10 days, asthma symptom disappears, and cough alleviates; Take 20 days, without band phlegm syndrome shape during cough; Take 25 days, cough transference cure; After use again Chinese medicine granules of the present invention to consolidate 10 days, drug withdrawal so far without recurrence.

embodiment: 3treat a Chinese medicine granules for chronic bronchitis, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Pericarpium Citri Reticulatae 8 parts, 12 parts, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae 8 parts, Radix Isatidis 8 parts, Radix Platycodonis 7 parts, Herba Taraxaci 8 parts, Rhizoma Coptidis 11 parts, Spica Prunellae 9 parts, 10 parts, Herba Ephedrae, Radix Ophiopogonis 5 parts, 6 parts, Poria, Herba Solidaginis 11 parts, Corm Eleocharitis 4 parts, Rhizoma Dioscoreae Nipponicae 10 parts, Stachys geobombycis C. Y. Wu 2.5 parts, Radix et Rhizoma Dysosmatis 6.5 parts, Herba Leibnitziae 5.5 parts, Flos Lonicerae 16 parts.

The preparation method of the Chinese medicine granules of above-mentioned treatment chronic bronchitis, step is as follows:

1. get Stachys geobombycis C. Y. Wu to clean, drain away the water, get the edible oil of Stachys geobombycis C. Y. Wu weight 1.5 times, put into the hot pot dryouied, drop into Stachys geobombycis C. Y. Wu, frying 4 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;

2. Pericarpium Citri Reticulatae, Radix Glycyrrhizae and Radix Platycodonis are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 90 mesh sieves stand-by;

3. Bulbus Fritillariae Cirrhosae, Radix Isatidis, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 8 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;

4. Spica Prunellae, Herba Ephedrae, Radix Ophiopogonis, Poria, Herba Solidaginis, Corm Eleocharitis, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 25 minutes, cover lid, decoction 8 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 5 days in the sunlight, dries 13 minutes slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;

5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Thick paste is dried 1.3 hours, obtain drying object, dry at temperature is 65 DEG C, pack.

model case three:boil XX, female, 42 years old, people from Jining City in Shandong Province, university teacher.Patient has chronic bronchitis for many years, and every day, cough was more than, and with asthma symptom when morning rises, every autumn and winter, symptom can increase the weight of, take NIANCIAN MILIAN CHUANBEI PIPA GAO substantially all not stop, symptom of coughing after taking can slightly alleviate, and but could not effect a radical cure always.

Take embodiment 3 gained Chinese medicine granules, every day twice, half an hour after meal morning and evening, get 10g, take after mixing it with hot water, take 6 days, play asthma symptom morning and obviously alleviate; Take 10 days, play asthma symptom morning and disappear, more than symptom of coughing has obvious alleviation; Take 20 days, still have cough symptom once in a while except when morning rises, other malaise symptoms all disappears; Take 1 first quarter moon, cough transference cure, recover, after use again Chinese medicine granules of the present invention to consolidate 10 days, after drug withdrawal without recurrence, have no side effect during taking Chinese medicine granules of the present invention appearance.

embodiment 4:treat a Chinese medicine granules for chronic bronchitis, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Pericarpium Citri Reticulatae 13 parts, 14 parts, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae 10 parts, Radix Isatidis 13 parts, Radix Platycodonis 9 parts, Herba Taraxaci 13 parts, Rhizoma Coptidis 13 parts, Spica Prunellae 11 parts, 12 parts, Herba Ephedrae, Radix Ophiopogonis 7 parts, 9 parts, Poria, Herba Solidaginis 15 parts, Corm Eleocharitis 7 parts, Rhizoma Dioscoreae Nipponicae 13 parts, Stachys geobombycis C. Y. Wu 3.5 parts, Radix et Rhizoma Dysosmatis 7.5 parts, Herba Leibnitziae 6.5 parts, Flos Lonicerae 17 parts.

The preparation method of the Chinese medicine granules of above-mentioned treatment chronic bronchitis, step is as follows:

1. get Stachys geobombycis C. Y. Wu to clean, drain away the water, get the edible oil of Stachys geobombycis C. Y. Wu weight 2.5 times, put into the hot pot dryouied, drop into Stachys geobombycis C. Y. Wu, frying 6 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;

2. Pericarpium Citri Reticulatae, Radix Glycyrrhizae and Radix Platycodonis are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 110 mesh sieves stand-by;

3. Bulbus Fritillariae Cirrhosae, Radix Isatidis, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 13 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;

4. Spica Prunellae, Herba Ephedrae, Radix Ophiopogonis, Poria, Herba Solidaginis, Corm Eleocharitis, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 35 minutes, cover lid, decoction 13 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 7 days in the sunlight, dries 18 minutes slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;

5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Thick paste is dried 1.8 hours, obtain drying object, dry at temperature is 75 DEG C, pack.

model case four:yellow XX, man, 51 years old, people from Dezhou City Shandong Province.Patient started the symptom occurring that cough is more than after certain cold, fever before 2 years, patient did not take notice of at that time, but hereafter whenever winter-spring season is often coughed, coughed white foam expectorant, was purulent sputum sometimes, repeatedly increases the weight of, and was chronic bronchitis through hospital diagnosis.In many ways seek medical advice and all cannot effect a radical cure.

Take Chinese medicine granules of the present invention, every day twice, half an hour after meal morning and evening, get 9g, take after mixing it with hot water, use 5 days, cough symptom obviously alleviates; Take 10 days, excessive phlegm symptom alleviates; Take 1 first quarter moon, rarely found expectorant disease during cough; Take 2 months, every malaise symptoms disappears, and recovers, with the appearance that has no side effect during Chinese medicine granules of the present invention.

embodiment 5:treat a Chinese medicine granules for chronic bronchitis, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Pericarpium Citri Reticulatae 11 parts, 13 parts, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae 9 parts, Radix Isatidis 12 parts, Radix Platycodonis 8 parts, Herba Taraxaci 11.5 parts, Rhizoma Coptidis 12 parts, Spica Prunellae 10 parts, 11 parts, Herba Ephedrae, Radix Ophiopogonis 6 parts, 7.5 parts, Poria, Herba Solidaginis 13 parts, Corm Eleocharitis 5 parts, Rhizoma Dioscoreae Nipponicae 11.5 parts, Stachys geobombycis C. Y. Wu 3 parts, Radix et Rhizoma Dysosmatis 7 parts, Herba Leibnitziae 6 parts, Flos Lonicerae 16.5 parts.

The preparation method of the Chinese medicine granules of above-mentioned treatment chronic bronchitis, step is as follows:

1. get Stachys geobombycis C. Y. Wu to clean, drain away the water, get the edible oil of Stachys geobombycis C. Y. Wu weight 2 times, put into the hot pot dryouied, drop into Stachys geobombycis C. Y. Wu, frying 5 minutes when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;

2. Pericarpium Citri Reticulatae, Radix Glycyrrhizae and Radix Platycodonis are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 100 mesh sieves stand-by;

3. Bulbus Fritillariae Cirrhosae, Radix Isatidis, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, slightly stewing 10 hours, takes out and drains yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;

4. Spica Prunellae, Herba Ephedrae, Radix Ophiopogonis, Poria, Herba Solidaginis, Corm Eleocharitis, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 30 minutes, cover lid, decoction 10 minutes, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 6 days in the sunlight, dries 15 minutes slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;

5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Thick paste is dried 1.5 hours, obtain drying object, dry at temperature is 70 DEG C, pack.

experimental exampleone: in order to verify the effect of Chinese medicine composition of the present invention (embodiment 5), we have extracted 400 patients and have carried out the experiment of medicine, be divided into experimental group and matched group, experimental group takes embodiment 5 gained Chinese medicine granules, and matched group takes Chinese medicine and the Western medicine medicine (such as the conventional medicine such as NIANCIAN MILIAN CHUANBEI PIPA GAO, amoxicillin) of other treatment chronic bronchitis.Inclusion criteria: through being diagnosed as chronic bronchitis patient, disease 1-10 in age, has chronic bronchitis clinical symptoms one or more.Curative effect situation criterion: 1, cure.After drug administration, malaise symptoms disappears completely; 2, effective.After drug administration, malaise symptoms alleviates or partial disappearance; 3, invalid.After drug administration, malaise symptoms is unchanged.

Table 1: two groups of Clinical efficacy comparison [example] tables 1

Table 1

Chinese medicine granules of the present invention cure rate compared with other medicine for the treatment of chronic bronchitis is high, total effective rate is 99%, and successful is better than matched group, and the Chinese medicine granules of this invention is cheap, ordinary people life-time service, also can not increase health and pecuniary burden.A routine side effect profile is there is not in clinical experiment, safety is far above the similar Chinese and western drugs for the treatment of chronic bronchitis, and instant effect, making the healing of chronic bronchitis be no longer can to ask and unavailable, is treat the ideal safe Chinese medicine granules of chronic bronchitis at present.

Claims (10)

1. treat a Chinese medicine granules for chronic bronchitis, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Pericarpium Citri Reticulatae 5-15 part, Radix Glycyrrhizae 8-17 part, Bulbus Fritillariae Cirrhosae 6-12 part, Radix Isatidis 5-15 part, Radix Platycodonis 6-10 part, Herba Taraxaci 5-15 part, Rhizoma Coptidis 10-14 part, Spica Prunellae 7-13 part, Herba Ephedrae 8-14 part, Radix Ophiopogonis 3-9 part, Poria 4-11 part, Herba Solidaginis 9-16 part, Corm Eleocharitis 3-8 part, Rhizoma Dioscoreae Nipponicae 8-15 part, Stachys geobombycis C. Y. Wu 2-4 part, Radix et Rhizoma Dysosmatis 6-8 part, Herba Leibnitziae 5-7 part, Flos Lonicerae 15-18 part.

2. the Chinese medicine granules for the treatment of chronic bronchitis according to claim 4, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Pericarpium Citri Reticulatae 8-13 part, Radix Glycyrrhizae 12-14 part, Bulbus Fritillariae Cirrhosae 8-10 part, Radix Isatidis 8-13 part, Radix Platycodonis 7-9 part, Herba Taraxaci 8-13 part, Rhizoma Coptidis 11-13 part, Spica Prunellae 9-11 part, Herba Ephedrae 10-12 part, Radix Ophiopogonis 5-7 part, Poria 6-9 part, Herba Solidaginis 11-15 part, Corm Eleocharitis 4-7 part, Rhizoma Dioscoreae Nipponicae 10-13 part, Stachys geobombycis C. Y. Wu 2.5-3.5 part, Radix et Rhizoma Dysosmatis 6.5-7.5 part, Herba Leibnitziae 5.5-6.5 part, Flos Lonicerae 16-17 part.

3. the Chinese medicine granules for the treatment of chronic bronchitis according to claim 4, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Pericarpium Citri Reticulatae 11 parts, 13 parts, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae 9 parts, Radix Isatidis 12 parts, Radix Platycodonis 8 parts, Herba Taraxaci 11.5 parts, Rhizoma Coptidis 12 parts, Spica Prunellae 10 parts, 11 parts, Herba Ephedrae, Radix Ophiopogonis 6 parts, 7.5 parts, Poria, Herba Solidaginis 13 parts, Corm Eleocharitis 5 parts, Rhizoma Dioscoreae Nipponicae 11.5 parts, Stachys geobombycis C. Y. Wu 3 parts, Radix et Rhizoma Dysosmatis 7 parts, Herba Leibnitziae 6 parts, Flos Lonicerae 16.5 parts.

4. the preparation method of the Chinese medicine granules for the treatment of chronic bronchitis according to claim 4, is characterized in that: step is as follows:

1. get Stachys geobombycis C. Y. Wu to clean, drain away the water, get Stachys geobombycis C. Y. Wu weight 1-3 edible oil doubly, put into the hot pot dryouied, drop into Stachys geobombycis C. Y. Wu, frying 3-7 minute when surrounding plays cigarette in pot, it is stand-by to grind to form smalls;

2. Pericarpium Citri Reticulatae, Radix Glycyrrhizae and Radix Platycodonis are cut into silk, are placed in preheated container, to fry to surperficial buff with slow fire and thorn is burnt, inner light yellow time take out and dry in the air cool to room temperature, grind to form fine powder, cross 80-120 mesh sieve stand-by;

3. Bulbus Fritillariae Cirrhosae, Radix Isatidis, Herba Taraxaci and Rhizoma Coptidis are cleaned, the spray of stripping and slicing yellow wine is even, and slightly stewing 5-15 hour, takes out and drain yellow wine, to be placed in pot micro-stir-fry to crisp, and it is stand-by to grind to form smalls while hot;

4. Spica Prunellae, Herba Ephedrae, Radix Ophiopogonis, Poria, Herba Solidaginis, Corm Eleocharitis, Rhizoma Dioscoreae Nipponicae, Radix et Rhizoma Dysosmatis, Herba Leibnitziae and Flos Lonicerae are placed in marmite, decoct with water to boiling, turn slow fire boiling 20-40 minute, cover lid, at decoction 5-15 minute, filters, filtrate is for subsequent use, filtering residue is exposed to the sun 4-8 days in the sunlight, dries 10-20 minute slowly being placed in little fire on iron plate, and it is stand-by to grind to form smalls;

5. by step 4. gained filtrate slowly heat, when filtrate is concentrated into 1/2 of original volume, drop into step 1.-4. gained smalls, fully stir into thick paste; Thick paste is dried 1-2 hour, obtains drying object, dry at temperature is 60-80 DEG C, pack.

5. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: 1. step gets Stachys geobombycis C. Y. Wu weight 1.5-2.5 edible oil doubly (preferred, to get the edible oil of Stachys geobombycis C. Y. Wu weight 2 times).

6. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: step 2. fine powder crosses 90-110 mesh sieve (preferred, fine powder, crosses 100 mesh sieves).

7. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: step is slightly stewing 8-13 hour 3., takes out and drains yellow wine (preferred, slightly stewing 10 hours, to take out and drain yellow wine).

8. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: 4. step decocts with water to boiling, turns slow fire boiling 25-35 minute (preferred, to decoct with water to boiling, turn slow fire boiling 30 minutes).

9. the preparation method of Chinese medicine granules according to claim 4, it is characterized in that: step 4. filtering residue is exposed to the sun 5-7 days in the sunlight, slowly dry 13-18 minute (preferred, filtering residue is exposed to the sun 6 days in the sunlight, be placed in little fire on iron plate dry 15 minutes slowly) being placed in little fire on iron plate.

10. the preparation method of Chinese medicine granules according to claim 4, is characterized in that: 5. thick paste is dried 1.3-1.8 hour by step, obtains drying object, it is dry (preferred at temperature is 65-75 DEG C, thick paste is dried 1.5 hours, obtain drying object, dry at temperature is 70 DEG C).