Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of postoperative pneumonia, Chinese medicine preparation of the present invention adopts modern advanced medical pharmaceutical technology to make, can effectively treat postoperative pneumonia, can improve postoperative pneumonia patient symptom, and it is definite to have drug effect, have no side effect, be difficult for more afterwards the feature of recurrence, be worth wide popularization and application clinically.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for postoperative pneumonia, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of postoperative pneumonia, comprise following processing step:
(1) Radix Clerodenri Cyrtophylli, Pericarpium Lagenariae sicerariae, Fructus kaki Siccus, Flos Hibisci Rosae-Sinensis, Caulis Phragmitis and Fructus Momordicae are cleaned, dried, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, reserved filtrate is for subsequent use;
(2) Fel Rana nigromaculata, Herba Carpesii Cernui, Herba Taraxaci and Bulbus Cardiocrini Cathayani are cleaned, put into container, strand juice, filter impurity, stays juice for subsequent use;
(3) Semen Benincasae is clean, put in pot and fry and be yellow to surface with slow fire, after taking-up cools, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Folium et Ramulus Callicarpae nudiflorae and Cortex Betulae Luminiferae are mixed, after mix homogeneously, carry out pulverization process, grind into powder, cross 100 order fine powders, for subsequent use;
(5) Herba Thuniae Albae and Folium Nerviliae fordii are cleaned, dried, be placed in container, add 80% the alcohol solution dipping 1~2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, is concentrated into the thick paste that 60 ℃ of relative densities are 1.11~1.16 for subsequent use;
(6) Semen Caryae Cathayensis is dried, spray yellow wine and run through, be placed in frying pan and be fried to micro-doing, take out, dry, grind into powder, cross 200 order fine powders, for subsequent use;
(7) get above-mentioned steps (1)~(6) prepared filtrate, juice, fine powder and thick paste and mix, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment postoperative pneumonia.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Thuniae Albae: sweet, flat; Return lung, stomach, kidney channel.Relieving cough and asthma, blood circulation promoting and blood stasis dispelling.Control pneumonia, tracheitis, bronchitis, gastric and duodenal ulcers, fracture, traumatic injury impairment caused by overstrain." choosing of Simao, Yunnan Chinese herbal medicine " carries: " nourishing YIN and moistening the lung, relieving cough and resolving phlegm.Control pulmonary tuberculosis, pneumonia, tracheitis, bronchitis, gastric and duodenal ulcers.”
Radix Clerodenri Cyrtophylli: hardship, cold; GUIXIN, Liver Channel.Heat clearing away, removing toxic substances, removing heat from blood.Main encephalitis b, epidemic encephalitis, the high heat of flu, parotitis, heat in blood is sent out class, measles pneumonia, icterohepatitis, diarrhea of heat type hematodiarrhoea, rheumatism pyretic arthralgia, headache, laryngopharynx swelling and pain, acute toothache, orchitis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, dissipating blood stasis hemostasis.Control enteritis, bacillary dysentery, pharyngolaryngitis, tonsillitis, parotitis, cold, fever, gingiva bleeding gingival hemorrhage.”
Folium et Ramulus Callicarpae nudiflorae: hemostasis, antiinflammatory, blood stasis dispelling, pain relieving.Control hemorrhage that pneumorrhagia type leptospirosis, pulmonary tuberculosis, lung abscess, lobar pneumonia etc. cause, the upper gastrointestinal hemorrhage that Peptic Ulcers etc. cause, thrombocytopenic purpura, hematuria, wound hemorrhage, influenza, burn, suppurative skin ulcer, cervical erosion, traumatic injury, rheumatalgia.Carry in " south of the Five Ridges gather medicinal herbs record ": " decoct washing traumatic injury wound, can eliminating blood stasis to promote regeneration of blood.As swelling due to wind, leaf is decocted to washing, get its stalk and lean pork decoction, can wind dispelling detumescence.”
Cortex Betulae Luminiferae: hardship, flat.Clearing away heat-damp and promoting diuresis, removing toxic substances.For acute tonsillitis, bronchitis, pneumonia, enteritis, dysentery, hepatitis, oliguria yellow skin, acute mastitis; Burn and scald is controlled in external, carbuncle furuncle and phyma poison.
Semen Benincasae: sweet in the mouth, cold nature; Return lung, large intestine channel.Lung heat clearing, reduce phlegm, evacuation of pus, be applicable to the diseases such as cough due to lung-heat, lung abscess, acute appendicitis." Shandong Chinese medicine " carries: " control nephritis, urethritis, dysuria, beriberi, edema.”
Pericarpium Lagenariae sicerariae: sweet in the mouth, light, property is flat; Return lung, spleen, kidney channel.Diuretic, detumescence, logical woods, eliminating stagnation.Main edema, ascites, jaundice, quenches one's thirst, gonorrhea, carbuncle." Luchuan book on Chinese herbal medicine " carries: " xeropulmonary cough is controlled in lung moistening.”
Fel Rana nigromaculata: bitter in the mouth, cold in nature; Return lung meridian.Heat-clearing and toxic substances removing, cure mainly pharyngeal waste rotten, or light disease pharyngeal diphtheria." Jilin Chinese herbal medicine " carries: " control measles complicated pneumonia.”
Herba Carpesii Cernui: bitter, acrid, cold; Slightly poisonous.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For cold, fever, laryngopharynx swelling and pain, toothache, acute enteritis, dysentery, urinary tract infection, tuberculous lymphadenitis; Furuncle toxic swelling, mastitis, parotitis, herpes zoster, venom are controlled in external." Yunnan Chinese herbal medicine " carries: " control infantile pneumonia, urinary tract infection.Furuncle is mashed deposited affected part with fresh leaf.”
Folium Nerviliae fordii: bitter, sweet, flat.Clearing away lung-heat to relieve cough, spleen invigorating removing food stagnancy, sedation-analgesia, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, for pulmonary tuberculosis cough spitting of blood, bronchitis, infantile malnutrition, infantile pneumonia, psychosis, treating swelling and pain by traumatic injury, stomatitis, acute laryngitis, sore." Nanning City's medicine will " carries: " nourishing the lung to arrest cough antipyreticly clears away heart-fire.Control pulmonary tuberculosis, and separate carbon monoxide poisoning.”
Semen Caryae Cathayensis: lung moistening is nourished, and controls dermatosis." Tianmu Mountains of Zhejiang Province medicine is planted will " carries: " kernel: moisten and take a tonic or nourishing food to build up one's health; Micro-stir-fry; Huang spills and takes, and controls lumbago.Fresh root bark is decocted soup and is embathed, and controls foot hemorrhoid, toe space pruritus due to damp pathogen.Control skin tinea.”
Fructus kaki Siccus: sweet, property is flat, tepor.Lung moistening, astringing intestine to stop diarrhea, hemostasis.Control haematemesis, spitting of blood, stranguria with blood, hemorrhoidal hamorrhage, anal fistula, dysentery." explaining abstruseness of the canon of materia medica " carries: " only gastric heat xerostomia, profit cardiopulmonary, expectorant.Control stranguria with blood, have blood in stool.”
Flos Hibisci Rosae-Sinensis: sweet, light, flat; GUIXIN, lung, liver, spleen channel.Lung heat clearing, reduces phlegm, removing heat from blood, removing toxic substances.Control phlegm-fire cough, epistaxis, dysentery, reddish and whitish turbid urine, carbuncle, skin infection." Luchuan book on Chinese herbal medicine " carries: " removing pathogenic heat from blood and toxic substance from the body.Control heat in blood, epistaxis, pruritus, skin infection.”
Caulis Phragmitis: sweet, cold, nontoxic; Enter the heart, lung meridian.Lung-heat clearing and detoxification, cough-relieving evacuation of pus, main lung abscess vomiting pus, cough due to lung-heat, carbuncle." herbal classic is met former " carries: " Rhizoma Phragmitis hollow, specially in sharp key, the kind lung abscess, vomiting bloody pus fetid sputum controlled.”
Herba Taraxaci: bitter, sweet, cold; Return liver, stomach warp.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria." occupying diet spectrum with breath " carries: " lung heat clearing, profit is coughed and reduced phlegm, eliminating stagnation eliminating carbuncle, yin nourishing removing heat from blood, relaxing muscles and tendons teeth consolidating, lactogenesis benefit essence.”
Bulbus Cardiocrini Cathayani: bitter in the mouth, micro-sweet, cool in nature.Clearing away lung-heat to relieve cough, removing toxic substances and promoting subsidence of swelling, main flu, cough due to lung-heat, spitting of blood, nasal sinusitis, ceruminal impaction, acute mastitis, innominate toxic swelling." Guizhou folk medicine " carries: " detumescence, detoxification.”
Fructus Momordicae: sweet, cool; Return lung, large intestine channel.Clearing heat and moistening lung, laxation relieving constipation, for lung-fire cough caused by dryness, pharyngalgia aphonia, dryness of the intestine constipation." Guangxi Chinese medicinal herbal " carries: " cough-relieving heat clearing away, removing heat from blood intestine moistening.Control cough, the dry gastric heat constipation of blood etc.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention has effect of clearing away lung-heat to relieve cough, sedation-analgesia, spleen invigorating removing food stagnancy, heat-clearing and toxic substances removing, and treatment postoperative pneumonia is had to short treating period, instant effect, the effect for the treatment of both the principal and secondary aspects of a disease; Chinese medicine preparation of the present invention adopts modern advanced medical pharmaceutical technology to make, and can effectively treat postoperative pneumonia, can improve postoperative pneumonia patient symptom, and drug effect is definite, has no side effect, and is difficult for more afterwards recurrence, is worth wide popularization and application clinically.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Treat a preparation method for the Chinese medicine preparation of postoperative pneumonia, comprise following processing step:
(1) Radix Clerodenri Cyrtophylli, Pericarpium Lagenariae sicerariae, Fructus kaki Siccus, Flos Hibisci Rosae-Sinensis, Caulis Phragmitis and Fructus Momordicae are cleaned, dried, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, reserved filtrate is for subsequent use;
(2) Fel Rana nigromaculata, Herba Carpesii Cernui, Herba Taraxaci and Bulbus Cardiocrini Cathayani are cleaned, put into container, strand juice, filter impurity, stays juice for subsequent use;
(3) Semen Benincasae is clean, put in pot and fry and be yellow to surface with slow fire, after taking-up cools, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Folium et Ramulus Callicarpae nudiflorae and Cortex Betulae Luminiferae are mixed, after mix homogeneously, carry out pulverization process, grind into powder, cross 100 order fine powders, for subsequent use;
(5) Herba Thuniae Albae and Folium Nerviliae fordii are cleaned, dried, be placed in container, add 80% the alcohol solution dipping 1~2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, is concentrated into the thick paste that 60 ℃ of relative densities are 1.11~1.16 for subsequent use;
(6) Semen Caryae Cathayensis is dried, spray yellow wine and run through, be placed in frying pan and be fried to micro-doing, take out, dry, grind into powder, cross 200 order fine powders, for subsequent use;
(7) get above-mentioned steps (1)~(6) prepared filtrate, juice, fine powder and thick paste and mix, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment postoperative pneumonia.
Usage and dosage: oral, every day 3 times, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3~4 courses for the treatment of.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of postoperative pneumonia, the routine clinical observation of postoperative pneumonia patient 100 that selection is made a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group 50 examples, wherein male's 26 examples at random, women's 24 examples, 50~75 years old age, 62.5 years old mean age, the shortest person of the course of disease 10 days, elder 2 months, average 32 days.
Matched group 50 examples, wherein male's 25 examples, women's 25 examples, 51~76 years old age, 62.8 years old mean age, the shortest person of the course of disease 12 days, elder 2 months, average 31 days.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 3 times, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3~4 courses for the treatment of.
Matched group is taken josamycin tablet, 0.8~1.2g on the one, and heavier infection can increase to 1.6g on the one, takes on an empty stomach, within 12 days, is 1 course for the treatment of, and 2 courses for the treatment of of the lighter, severe one can be fully recovered 3~6 courses for the treatment of, and the person of being in a bad way is conventionally invalid.
3, efficacy determination:
(1) cure: postoperative pneumonia symptom all disappears, and physical recovery is normal, body index recovers normal on inspection.
(2) effective: postoperative pneumonia transference cure, body index recovers normal substantially on inspection.
(3) effective: postoperative pneumonia symptom disappears substantially, body index part takes a turn for the better on inspection.
(4) invalid: by treating rear symptom without being clearly better.
4, result:
The comprehensive therapeutic effect for the treatment of group and matched group, sees the following form:
Group |
Cure |
Effective |
Effectively |
Invalid |
Cure rate |
Total effective rate |
Treatment group |
23 |
19 |
6 |
2 |
46% |
96% |
Matched group |
10 |
11 |
10 |
19 |
20% |
62% |
More than in table, result shows, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Chinese medicine preparation of the present invention has effect of clearing away lung-heat to relieve cough, sedation-analgesia, spleen invigorating removing food stagnancy, heat-clearing and toxic substances removing, and treatment postoperative pneumonia is had to short treating period, instant effect, the effect for the treatment of both the principal and secondary aspects of a disease; Chinese medicine preparation of the present invention adopts modern advanced medical pharmaceutical technology to make, and can effectively treat postoperative pneumonia, can improve postoperative pneumonia patient symptom, and drug effect is definite, has no side effect, and is difficult for more afterwards recurrence, is worth wide popularization and application clinically.