Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of postoperative pneumonia, Chinese medicine preparation of the present invention adopts modern advanced medical pharmaceutical technology to make, effectively can treat postoperative pneumonia, postoperative pneumonia patients symptomatic can be improved, and it is definite to have drug effect, have no side effect, the feature not easily recurred more, is worth wide popularization and application clinically.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for postoperative pneumonia, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of postoperative pneumonia, comprise following processing step:
(1) Radix Clerodenri Cyrtophylli, Pericarpium Lagenariae sicerariae, Fructus kaki Siccus, Flos Hibisci Rosae-Sinensis, Caulis Phragmitis and Fructus Momordicae are cleaned, dry, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(2) Fel Rana nigromaculata, Herba Carpesii Cernui, Herba Taraxaci and Bulbus Cardiocrini Cathayani are cleaned, put into container, strand juice, filter impurity, stays juice for subsequent use;
(3) Semen Benincasae is cleaned, put in pot to fry with slow fire and take out after cooling to surperficial in yellow, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Folium et Ramulus Callicarpae nudiflorae and Cortex Betulae Luminiferae are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 100 order fine powders, for subsequent use;
(5) Herba Thuniae Albae and Folium Nerviliae fordii are cleaned, dry, be placed in container, add the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, be concentrated into 60 DEG C of relative densities be 1.11 ~ 1.16 thick paste for subsequent use;
(6) Semen Caryae Cathayensis is dried, spray yellow wine and run through, be placed in frying pan and be fried to micro-doing, take out, dry, grind into powder, cross 200 order fine powders, for subsequent use;
(7) get the filtrate obtained by above-mentioned steps (1) ~ (6), juice, fine powder and thick paste mixing, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment postoperative pneumonia.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Thuniae Albae: sweet is flat; Return lung, stomach, kidney channel.Relieving cough and asthma, blood circulation promoting and blood stasis dispelling.Control pneumonia, tracheitis, bronchitis, gastric and duodenal ulcers, fracture, traumatic injury impairment caused by overstrain." choosing of Simao, Yunnan Chinese herbal medicine " carries: " nourishing YIN and moistening the lung, relieving cough and resolving phlegm.Control pulmonary tuberculosis, pneumonia, tracheitis, bronchitis, gastric and duodenal ulcers.”
Radix Clerodenri Cyrtophylli: bitter, cold; GUIXIN, Liver Channel.Heat clearing away, removing toxic substances, removing heat from blood.Main encephalitis b, epidemic encephalitis, the high heat of flu, parotitis, heat in blood sends out class, measles pneumonia, icterohepatitis, diarrhea of heat type hematodiarrhoea, beriberoid pyretic arthralgia, headache, laryngopharynx swelling and pain, acute toothache, orchitis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " dissipating blood stasis stops blooding for clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body.Control enteritis, bacillary dysentery, pharyngolaryngitis, tonsillitis, parotitis, cold, fever, gingiva bleeding gingival hemorrhage.”
Folium et Ramulus Callicarpae nudiflorae: hemostasis, antiinflammatory, blood stasis dispelling, pain relieving.That controls that pneumorrhagia type leptospirosis, pulmonary tuberculosis, lung abscess, lobar pneumonia etc. cause is hemorrhage, the upper gastrointestinal hemorrhage that Peptic Ulcers etc. cause, thrombocytopenic purpura, hematuria, wound hemorrhage, influenza, burn, suppurative skin ulcer, cervical erosion, traumatic injury, rheumatalgia." south of the Five Ridges gather medicinal herbs record " carries: " decoct washing traumatic injury wound, can eliminating blood stasis to promote regeneration of blood.As swelling due to wind, leaf is decocted washing, get its stalk and lean pork decoction, can wind dispelling detumescence.”
Cortex Betulae Luminiferae: bitter is flat.Clearing away heat-damp and promoting diuresis, removing toxic substances.For acute tonsillitis, bronchitis, pneumonia, enteritis, dysentery, hepatitis, oliguria yellow skin, acute mastitis; Burn and scald is controlled in external, carbuncle furuncle and phyma poison.
Semen Benincasae: sweet in the mouth, cold nature; Return lung, large intestine channel.Lung heat clearing, reduce phlegm, evacuation of pus, be applicable to the diseases such as cough due to lung-heat, lung abscess, acute appendicitis." Shandong Chinese medicine " carries: " control nephritis, urethritis, dysuria, beriberi, edema.”
Pericarpium Lagenariae sicerariae: sweet in the mouth, light, property is put down; Return lung, spleen, kidney channel.Diuretic, detumescence, logical woods, eliminating stagnation.Main edema, ascites, jaundice, quenches one's thirst, gonorrhea, carbuncle." Luchuan book on Chinese herbal medicine " carries: " xeropulmonary cough is controlled in lung moistening.”
Fel Rana nigromaculata: bitter in the mouth, cold in nature; Return lung meridian.Heat-clearing and toxic substances removing, cure mainly pharyngeal waste rotten, or mild pharyngeal diphtheria." Jilin Chinese herbal medicine " carries: " control measles complicated pneumonia.”
Herba Carpesii Cernui: bitter, acrid, cold; Slightly poisonous.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For cold, fever, laryngopharynx swelling and pain, toothache, acute enteritis, dysentery, urinary tract infection, tuberculous lymphadenitis; Furuncle toxic swelling is controlled in external, mastitis, parotitis, herpes zoster, venom." Yunnan Chinese herbal medicine " carries: " control infantile pneumonia, urinary tract infection.The fresh leaf of furuncle mashes deposited affected part.”
Folium Nerviliae fordii: bitter, sweet, flat.Clearing away lung-heat to relieve cough, spleen invigorating removing food stagnancy, sedation-analgesia, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, for pulmonary tuberculosis cough spitting of blood, bronchitis, infantile malnutrition, infantile pneumonia, psychosis, treating swelling and pain by traumatic injury, stomatitis, acute laryngitis, sore." Nanning City's medicine will " carries: " nourishing the lung to arrest cough antipyreticly clears away heart-fire.Control pulmonary tuberculosis, and separate carbon monoxide poisoning.”
Semen Caryae Cathayensis: lung moistening is nourished, and controls dermatosis." will planted by Tianmu Mountains of Zhejiang Province medicine " carries: " kernel: moisten and take a tonic or nourishing food to build up one's health; Micro-stir-fry; Huang spills and takes, and controls lumbago.Fresh root bark is decocted soup and is embathed, and controls foot hemorrhoid, toe space pruritus due to damp pathogen.Control skin tinea.”
Fructus kaki Siccus: sweet, property is put down, tepor.Lung moistening, astringing intestine to stop diarrhea, hemostasis.Control haematemesis, spitting of blood, stranguria with blood, hemorrhoidal hamorrhage, anal fistula, dysentery." explaining abstruseness of the canon of materia medica " carries: " only gastric heat xerostomia, profit cardiopulmonary, expectorant.Control stranguria with blood, have blood in stool.”
Flos Hibisci Rosae-Sinensis: sweet is light, flat; GUIXIN, lung, liver, spleen channel.Lung heat clearing, reduces phlegm, removing heat from blood, removing toxic substances.Control phlegm-fire cough, epistaxis, dysentery, reddish and whitish turbid urine, carbuncle, skin infection." Luchuan book on Chinese herbal medicine " carries: " removing pathogenic heat from blood and toxic substance from the body.Control heat in blood, epistaxis, pruritus, skin infection.”
Caulis Phragmitis: sweet, cold, nontoxic; Enter the heart, lung meridian.Lung-heat clearing and detoxification, cough-relieving evacuation of pus, main lung abscess vomiting pus, cough due to lung-heat, carbuncle." herbal classic is met former " carries: " Rhizoma Phragmitis hollow, specially in sharp key, is apt to control lung abscess, vomiting bloody pus fetid sputum.”
Herba Taraxaci: bitter, sweet, cold; Return liver, stomach warp.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria." occupying diet spectrum with breath " carries: " lung heat clearing, profit is coughed and reduced phlegm, eliminating stagnation eliminating carbuncle, yin nourishing removing heat from blood, relaxing muscles and tendons teeth consolidating, lactogenesis benefit essence.”
Bulbus Cardiocrini Cathayani: bitter in the mouth, micro-sweet, cool in nature.Clearing away lung-heat to relieve cough, removing toxic substances and promoting subsidence of swelling, main flu, cough due to lung-heat, spitting of blood, nasal sinusitis, ceruminal impaction, acute mastitis, innominate toxic swelling." Guizhou folk medicine " carries: " detumescence, detoxification.”
Fructus Momordicae: sweet is cool; Return lung, large intestine channel.Clearing heat and moistening lung, laxation relieving constipation, for lung-fire cough caused by dryness, pharyngalgia aphonia, dryness of the intestine constipation." Guangxi Chinese medicinal herbal " carries: " cough-relieving heat clearing away, removing heat from blood intestine moistening.Control cough, the dry gastric heat constipation of blood etc.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention has effect of clearing away lung-heat to relieve cough, sedation-analgesia, spleen invigorating removing food stagnancy, heat-clearing and toxic substances removing, has short treating period, instant effect, the effect for the treatment of both the principal and secondary aspects of a disease to treatment postoperative pneumonia; Chinese medicine preparation of the present invention adopts modern advanced medical pharmaceutical technology to make, and effectively can treat postoperative pneumonia, can improve postoperative pneumonia patients symptomatic, and drug effect is definite, has no side effect, not easily recurs more, be worth wide popularization and application clinically.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Treat a preparation method for the Chinese medicine preparation of postoperative pneumonia, comprise following processing step:
(1) Radix Clerodenri Cyrtophylli, Pericarpium Lagenariae sicerariae, Fructus kaki Siccus, Flos Hibisci Rosae-Sinensis, Caulis Phragmitis and Fructus Momordicae are cleaned, dry, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, reserved filtrate is for subsequent use;
(2) Fel Rana nigromaculata, Herba Carpesii Cernui, Herba Taraxaci and Bulbus Cardiocrini Cathayani are cleaned, put into container, strand juice, filter impurity, stays juice for subsequent use;
(3) Semen Benincasae is cleaned, put in pot to fry with slow fire and take out after cooling to surperficial in yellow, grind into powder, cross 160 order fine powders, for subsequent use;
(4) Folium et Ramulus Callicarpae nudiflorae and Cortex Betulae Luminiferae are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 100 order fine powders, for subsequent use;
(5) Herba Thuniae Albae and Folium Nerviliae fordii are cleaned, dry, be placed in container, add the alcohol solution dipping 1 ~ 2 hour of 80% of 4 times amount, heating extraction 3 hours, reclaim ethanol, be concentrated into 60 DEG C of relative densities be 1.11 ~ 1.16 thick paste for subsequent use;
(6) Semen Caryae Cathayensis is dried, spray yellow wine and run through, be placed in frying pan and be fried to micro-doing, take out, dry, grind into powder, cross 200 order fine powders, for subsequent use;
(7) get the filtrate obtained by above-mentioned steps (1) ~ (6), juice, fine powder and thick paste mixing, utilize modern advanced pharmacy science and technology, make capsule, be the Chinese medicine preparation of described treatment postoperative pneumonia.
Usage and dosage: oral, every day 3 times, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3 ~ 4 courses for the treatment of.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of postoperative pneumonia, select the routine clinical observation of postoperative pneumonia patient 100 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 50 example, wherein male 26 example, women 24 example, 50 ~ 75 years old age, 62.5 years old mean age, the shortest person of the course of disease 10 days, most elder 2 months, average 32 days.
Matched group 50 example, wherein male 25 example, women 25 example, 51 ~ 76 years old age, 62.8 years old mean age, the shortest person of the course of disease 12 days, most elder 2 months, average 31 days.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 3 times, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3 ~ 4 courses for the treatment of.
Matched group takes josamycin tablet, 0.8 ~ 1.2g on the one, and heavier infection can increase to 1.6g on the one, takes on an empty stomach, within 12 days, is 1 course for the treatment of, 2 courses for the treatment of of the lighter, and severe one can be fully recovered 3 ~ 6 courses for the treatment of, and the person of being in a bad way is usually invalid.
3, efficacy determination:
(1) cure: postoperative pneumonia symptom all disappears, physical recovery is normal, and body index recovers normal on inspection.
(2) effective: postoperative pneumonia transference cure, body index recovers normal substantially on inspection.
(3) effective: postoperative pneumonia symptom disappears substantially, body index part takes a turn for the better on inspection.
(4) invalid: by treating rear symptom without being clearly better.
4, result:
The comprehensive therapeutic effect for the treatment of group and matched group, sees the following form:
Group |
Cure |
Effective |
Effectively |
Invalid |
Cure rate |
Total effective rate |
Treatment group |
23 |
19 |
6 |
2 |
46% |
96% |
Matched group |
10 |
11 |
10 |
19 |
20% |
62% |
More than result display in table, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Chinese medicine preparation of the present invention has effect of clearing away lung-heat to relieve cough, sedation-analgesia, spleen invigorating removing food stagnancy, heat-clearing and toxic substances removing, has short treating period, instant effect, the effect for the treatment of both the principal and secondary aspects of a disease to treatment postoperative pneumonia; Chinese medicine preparation of the present invention adopts modern advanced medical pharmaceutical technology to make, and effectively can treat postoperative pneumonia, can improve postoperative pneumonia patients symptomatic, and drug effect is definite, has no side effect, not easily recurs more, be worth wide popularization and application clinically.