CN103768398B - Traditional Chinese medicine composition for treating advanced lung tumors - Google Patents
Traditional Chinese medicine composition for treating advanced lung tumors Download PDFInfo
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- CN103768398B CN103768398B CN201410068585.0A CN201410068585A CN103768398B CN 103768398 B CN103768398 B CN 103768398B CN 201410068585 A CN201410068585 A CN 201410068585A CN 103768398 B CN103768398 B CN 103768398B
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Abstract
The invention discloses a medicament and particularly discloses a traditional Chinese medicine composition for treating advanced lung tumors. The traditional Chinese medicine composition for treating advanced lung tumors is characterized by comprising the following components in parts by weight: 20-30 parts of codonopsis pilosula, 20-30 parts of radix astragali, 10-15 parts of alcohol processed radix angelica sinensis, 20-30 parts of roasted rhizoma atractylodis macrocephalae, 20-30 parts of tuckahoe, 10-15 parts of grifola, 10-20 parts of ginger processed pinellia, 10-20 parts of dried orange peel, 6-12 parts of white mustard seed, 10-15 parts of radix glehniae, 6-9 parts of pseudo-ginseng, 10-15 parts of pseudobulbus cremastrae seu pleiones, 15-30 parts of oldenlandia diffusa, 15-30 parts of sculellaria barbata, 15-30 parts of dandelion, 20-30 parts of hairyvein agrimonia herb, 15-30 parts of cordate houttuynia, 20-30 parts of salvia chinensis, 20-30 parts of winged euonymus twig, 10-30 parts of radix ranunculi ternate, 6-12 parts of ganoderma lucidum, 3-6 parts of cordyceps taishanensis powder and 3 centipedes. The traditional Chinese medicine composition has the effects of benefiting the lung and tonifying the spleen, eliminating dampness and reducing phlegm, clearing heat and removing toxicity, counteracting toxic substances and removing stasis, treating qi, blood, phlegm and toxic substances, strengthening the body resistance and eliminating pathogenic factors as well as purging and tonifying jointly so as to achieve the purposes of eliminating or stabilizing a tumor nidus, improve syndromes, improve the life quality of patients and prolong the lifetime. The traditional Chinese medicine composition disclosed by the invention is remarkable in curative effects, safe and free of side effects, and the effective rate reaches 92%.
Description
Technical field
The invention mainly relates to the field of Chinese medicines, more particularly, to a kind of Chinese medicine composition treating late period lung tumor.
Background technology
Lung tumor is that M ＆ M increases the soonest, one of malignant tumor maximum to population health and life threat.The many countries of immediate and mid-term all report that the M ＆ M of lung tumor all substantially increases, and male's lung tumor incidence and mortality rate all account for first of all malignant tumor, and women sickness rate accounts for second, and mortality rate accounts for second.Primary disease is many to fall ill more than 40 years old, age of onset peak 60-79 year between.Men and women's prevalence is 2.3:1.Race, family members' history and smoking all have an impact to the morbidity of lung tumor.
At present in the method for the treatment of lung tumor：Doctor trained in Western medicine has operative treatment, radiotherapy, chemotherapy, immunization therapy, laser therapy, cold therapy, hyperpyrexia micro-wave therapeutic etc..But operative treatment has very big wound, Low patient is difficult to undertake, and postoperative easy generation complication, often relapse and metastasis.Toxic and side effects of chemoradiotherapy is big, must Long-term taking medicine, expensive, infringement patient's normal body function, and easily develop immunity to drugs and occur repeatedly it is impossible to therapeutic effect expected from obtaining.Particularly with late period lung tumor patient it is impossible to adopting excision and chemicotherapy side effect cannot being tolerated, it is a kind of desirable Therapeutic Method using traditional Chinese medicine conservative treatment.
Traditional Chinese Medicine have emphasize organic conception, strengthening vital QI to eliminate pathogenic factors, regulating yin and yang,
The advantages for the treatment of both the principal and secondary aspects of a disease, toxic and side effects are little, is increasingly approved by people.But, clinically lack the Chinese patent medicine for the treatment of late period lung tumor effect is significant at present.
Content of the invention
The object of the invention is exactly the defect in order to make up prior art, provides a kind of Chinese medicine composition treating late period lung tumor, and it is obvious for the curative effect for the treatment of late period lung tumor, safe ready, Small side effects.
The present invention is achieved by the following technical solutions：
A kind of Chinese medicine composition treating late period lung tumor it is characterised in that：The weight proportion of its each crude drug is：Radix Codonopsis 20-30, Radix Astragali 20-30, Radix Angelicae Sinensis (processed with wine) 10-15, Rhizoma Atractylodis Macrocephalae (parched) 20-30, Poria 20-30, Polyporus 10-15, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10-20, Pericarpium Citri Reticulatae 10-20, Bulbus Fritillariae Thunbergii 10-20, Radix Peucedani 15-20, sweet Radix Asteriss 6-12, sweet Flos Farfarae 6-12, Semen Armeniacae Amarum (parched) 10-20, Semen Sinapis Albae 6-12, Radix Glehniae 10-15, Radix Notoginseng 6-9, Pseudobulbus Cremastrae Seu Pleioness 10-15, Herba Hedyotidis Diffusae 15-30, Herba Scutellariae Barbatae 15-30, Herba Taraxaci 15-30, Herba Agrimoniae 20-30, Herba Houttuyniae 15-30, Herba Salviae Chinensiss 20-30, Ramulus Euonymi 20-30, Radix Ranunculi Ternati 10-30, Ganoderma 6-12
, Cordyceps powder 3-6, Scolopendra 3.
A kind of Chinese medicine composition treating late period lung tumor, it is preferably：The weight proportion of its each raw material is：Radix Codonopsis 30, the Radix Astragali 30, Radix Angelicae Sinensis (processed with wine) 12, Rhizoma Atractylodis Macrocephalae (parched) 30, Poria 30, Polyporus 12, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 12, Pericarpium Citri Reticulatae 15, Bulbus Fritillariae Thunbergii 15, Radix Peucedani 18, sweet Radix Asteriss 12, sweet Flos Farfarae 12, Semen Armeniacae Amarum (parched) 16, Semen Sinapis Albae 9, Radix Glehniae 12, Radix Notoginseng 9, Pseudobulbus Cremastrae Seu Pleioness 12, Herba Hedyotidis Diffusae 30, Herba Scutellariae Barbatae 30, Herba Taraxaci 30, Herba Agrimoniae 30, Herba Houttuyniae 30, Herba Salviae Chinensiss 30, Ramulus Euonymi 30, Radix Ranunculi Ternati 30, Ganoderma 12, Cordyceps powder 6, Scolopendra 3.
The compound method of the present invention is as follows：To decoct after above-mentioned herbal medicine immersion 1 hour, during decoction, moisture content exceedes 5 centimeters of Chinese medicine, poured out medicinal liquid and can be taken with after boiling by slow fire 30 minutes, filtering after boiling water, Scolopendra is dried to grind into powder and takes after mixing it with water.Divide sooner or later, twice a day.
Effect and mechanism：
Radix Astragali compatibility honey Radix Asteriss, sweet Flos Farfarae, treat lung qi deficient syndrome.Symptoms include cough with asthma is with the passing of time, shortness of breath and tired spirit, expectorant harmony brings up in lung is powerless.Radix Astragali QI invigorating, enriching spleen-QI can be risen, and can lung benefiting consolidating superficial resistance.Sweet Radix Asteriss, nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm, also there is the work(of antitumor.Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched), Poria, Radix Angelicae Sinensis compatibility, strengthen spleen and stomach function and QI invigorating, and QI invigorating can promote to enrich blood, and spleen invigorating can help hemopoietic, thus can enhancing human body immunity power, improve hemopoietic function, improve vital sign.Polyporusum bellatuss composition in Polyporus, has enhancing immunity, tumor inhibition effect.According to document, polyporus extract (predominantly polyporusum bellatuss) has more significant inhibitory action to mice transplanted tumor S-180.Inhibitory rate 50-70%, tumor-like hyperplasia reaches more than 30%.In the tumor-bearing mice of extracted thing treatment, there are about 6-7% completed tumor regression.Mice to completed tumor regression, inoculates tumor cell after the 1-6 month, does not all grow tumor.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI master, controls cough with copious phlegm, nausea and vomiting.Pericarpium Citri Reticulatae, regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Bulbus Fritillariae Thunbergii, removing heat-phlegm, powder detoxifcation.Control cough due to pathogenic wind-heat, lung carbuncle larynx numbness, scrofula, sore swollen toxin.Semen Armeniacae Amarum (parched), cough-relieving is coughed, expectorant lung moistening.Semen Sinapis Albae, reduces phlegm by drink；Mass dissipating and swelling eliminating Radix Glehniae, nourishing YIN and clearing away lung-heat, expelling phlegm for arresting cough Pseudobulbus Cremastrae Seu Pleioness, dispersing swelling and dissipating binds, resolving sputum, heat-clearing and toxic substances removing.Herba Hedyotidis Diffusae, cures mainly dyspnea and cough due to lung-heat；Laryngopharynx swelling and pain；Acute appendicitis；Furuncle and phyma skin infection；Venom；Puckery pain of heat gonorrhea；Edema；Dysentery；Enteritis；Jaundice due to damp-heat；It is good at treatment kinds of tumors to swell.Herba Salviae Chinensiss, blood circulation promoting and blood stasis dispelling；Clearing away heat-damp and promoting diuresis；Mass dissipating and swelling eliminating.Ramulus Euonymi, bitter, pungent, row spills into blood, has both been apt to drastically removing blood stasis and resolving static blood, is apt to promoting blood circulation and detumescence pain relieving again, and the efficacy of a drug is stronger.Herba Scutellariae Barbatae, heat clearing away, removing toxic substances, method wind, scattered blood, circulation of qi promoting, diuretic, dredging collateral, removing blood stasis with potent drugs, pain relieving.According to document, to the late tumor treating weary art, also play the role of to improve symptom, suppression tumor proliferation and extend patient vitals.Radix Ranunculi Ternati, dissipating phlegm and resolving masses, removing toxic substances and promoting subsidence of swelling, antitumor.According to document, the ethanol extract of Radix Ranunculi Ternati is to tumor necrosis factor（TNF）There is stronger induction role, in 36 kinds of screened Chinese herbal medicine, Radix Ranunculi Ternati（70% ethanol extract）Production of TNF induced effect is the strongest.Radix Notoginseng, warm in nature, acrid in the mouth, there is scattered silt hemostasis, effect of subduing swelling and relieving pain, cure mainly spitting of blood, spit blood, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.Ganoderma, cures mainly asthenia, cough, asthma, insomnia, dyspepsia, malignant tumor etc..There is enhancing immunity, antitumor action.Promote the generation waiting endogenouss antitumorigenic substance of interleukin II, promote phagocytic function, the index level of the hematopoietic potential especially leukocyte of lifting human body of mononuclear phagocyte, the wherein effective ingredient such as ganoderan has inhibitory action to tumor cell.Cordyceps powder, has kidney tonifying tonifying the lung, hemostasis and phlegm, cough-relieving are coughed, benefit is deficient, support vital essence, relieving asthma, the function of antitumor.Scolopendra, wind-dispelling, arresting convulsion, counteracting toxic substances, eliminating stagnation, antitumor.
The traditional Chinese medical science thinks that lung tumors are vital QI being weakened and pathogen being violent, weakened body resistance with the deficiency of vital energy, the deficiency of YIN, deficiency of both QI and YIN, with the stagnation of QI, blood stasis, expectorant coagulates the domination of pathogen, based on poison is poly-, is that a kind of whole body integrally belongs to empty, locally true, or the disease of simulataneous insufficiency and excessive.The present invention passes through lung benefiting spleen reinforcing, dehumidifying resolving sputum, heat-clearing and toxic substances removing, dispersing pathogen accumulation.Gas, blood, expectorant, poison are controlled altogether, with strengthening vital QI to eliminate pathogenic factors, reinforcement and elimination in combination.
Specific embodiment：
A kind of Chinese medicine composition treating late period lung tumor, it is preferably：The weight proportion of its each raw material（Unit g）For：Radix Codonopsis 30, the Radix Astragali 30, Radix Angelicae Sinensis (processed with wine) 12, Rhizoma Atractylodis Macrocephalae (parched) 30, Poria 30, Polyporus 12, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 12, Pericarpium Citri Reticulatae 15, Bulbus Fritillariae Thunbergii 15, Radix Peucedani 18, sweet Radix Asteriss 12, sweet Flos Farfarae 12, Semen Armeniacae Amarum (parched) 16, Semen Sinapis Albae 9, Radix Glehniae 12, Radix Notoginseng 9, Pseudobulbus Cremastrae Seu Pleioness 12, Herba Hedyotidis Diffusae 30, Herba Scutellariae Barbatae 30, Herba Taraxaci 30, Herba Agrimoniae 30, Herba Houttuyniae 30, Herba Salviae Chinensiss 30, Ramulus Euonymi 30, Radix Ranunculi Ternati 30, Ganoderma 12, Cordyceps powder 6, Scolopendra 3.
Weigh the raw material components of above corresponding group, according to the routine fashion of decoction, add water boiled into a decoction, Scolopendra is dried levigation and takes after mixing it with water, one dose per day（600ml）, one point of morning and evening sub-service.
Clinical observation：
(1) physical data：
The present inventor in 2005 so far, carries out clinical observation treatment to 100 patients.Wherein male 70, women 30,48 to 75 years old ages, small cell lung tumor 38, non-fire power 62.All belong to late period lung tumor patient, part early stage is treated through chemicotherapy, and side effect is excessive, when immune function depression or discovery
It has been patients with terminal.
(2) Therapeutic Method：
With the medicine of the present invention with being decocted in water for oral dose, sooner or later each 30 days is once a course for the treatment of, according to the state of an illness and recover speed and treat 6 months to 3 years.
(3) efficacy assessment standard：
Present invention is mainly used for treatment late period lung tumor, therefore improving situation and life span according to late period lung tumor symptom is criterion, is divided into following three kinds：
Effective：Cardinal symptom is obviously improved, survive 3 years or more, tumor cell no shifts and no spreads, or eliminates.
Effectively：Cardinal symptom is improved substantially；Existence 1-3, growth of tumour cell is inhibited.
Invalid：Symptom improves inconspicuous, Nasopharyngeal neoplasms diffusion, dead.
(4) therapeutic effect：
Clinical effective 18, effective 74, invalid 8, all cases all have no adverse reaction.
(5) summarize：Effective percentage 92%,
For proof, the present invention has good curative effect, enumerates model case as follows：
Case 1：Wang, man, 55 years old, patient was diagnosed as lung cancer in non-cellule type, four diagnostic methods data from May, 2005：Chest distress, cough with copious phlegm, thin color is white, abdominal distention and anorexia, spiritlessness and weakness, dynamic then tachypnea, enlarged tongue, indentations at the margin of the tongue, and lip and nail are dark violet, and pale tongue is partially dark, thin fur, and sublingual vein green grass or young crops is black and anger is opened, stringy and thready pulse.Do not do any other treatment schemes of performing the operation and take.Give the made decoction of the present invention, twice daily, after taking January, symptom is obviously improved, after 6 months, above-mentioned symptom disappears substantially, CT examination foci disappearance normal through examination in hospital indices.Existing patient can participate in Activities and physical work, no abnormal phenomenon, and follow-up is so far.
Case 2：Liu, man, 66 years old.Find have lung posterior lobe to have a 3CM*4CM lump during patient's in December, 2008 health check-up.Row resection operation after making a definite diagnosis, postoperative pathological shows：Right lung squamous cell carcinoma.Afterwards again through chemotherapy four times and multiple radiotherapy.Left Lung metastases are found when checking after three months.Symptoms include：Cough uncomfortable in chest, expectorant is yellow and glue, when and hemoptysis, out of breath uncomfortable in chest, thirsty vexed, hectic fever night sweat, dry pharynx celostomia, red tongue lacks tongue, stringy,thready and rapid pulse.Give the made decoction of the present invention, twice daily, after taking January, symptom is obviously improved, take 3 months, CT examination, the swollen thing of left lung has no diffusion, no transfer case.Continue and take 6 months, swollen thing focus is stable, patient's items vital sign is good.
Claims (2)
1. a kind of Chinese medicine composition treating late period lung tumor it is characterised in that：The weight proportion of its each raw material is：Radix Codonopsis 20-30, Radix Astragali 20-30, Radix Angelicae Sinensis (processed with wine) 10-15, Rhizoma Atractylodis Macrocephalae (parched) 20-30, Poria 20-30, Polyporus 10-15, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10-20, Pericarpium Citri Reticulatae 10-20, Bulbus Fritillariae Thunbergii 10-20, Radix Peucedani 15-20, sweet Radix Asteriss 6-12, sweet Flos Farfarae 6-12, Semen Armeniacae Amarum (parched) 10-20, Semen Sinapis Albae 6-12, Radix Glehniae 10-15, Radix Notoginseng 6-9, Pseudobulbus Cremastrae Seu Pleioness 10-15, Herba Hedyotidis Diffusae 15-30, Herba Scutellariae Barbatae 15-30, Herba Taraxaci 15-30, Herba Agrimoniae 20-30, Herba Houttuyniae 15-30, Herba Salviae Chinensiss 20-30, Ramulus Euonymi 20-30, Radix Ranunculi Ternati 10-30, Ganoderma 6-12
, Cordyceps powder 3-6, Scolopendra 3.
2. Chinese medicine composition as claimed in claim 1 it is characterised in that：The weight proportion of its each raw material is：Radix Codonopsis 30, the Radix Astragali 30, Radix Angelicae Sinensis (processed with wine) 12, Rhizoma Atractylodis Macrocephalae (parched) 30, Poria 30, Polyporus 12, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 12, Pericarpium Citri Reticulatae 15, Bulbus Fritillariae Thunbergii 15, Radix Peucedani 18, sweet Radix Asteriss 12, sweet Flos Farfarae 12, Semen Armeniacae Amarum (parched) 16, Semen Sinapis Albae 9, Radix Glehniae 12, Radix Notoginseng 9, Pseudobulbus Cremastrae Seu Pleioness 12, Herba Hedyotidis Diffusae 30, Herba Scutellariae Barbatae 30, Herba Taraxaci 30, Herba Agrimoniae 30, Herba Houttuyniae 30, Herba Salviae Chinensiss 30, Ramulus Euonymi 30, Radix Ranunculi Ternati 30, Ganoderma 12, Cordyceps powder 6, Scolopendra 3.
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| CN104547810A (en) * | 2014-12-30 | 2015-04-29 | 范士怀 | Traditional Chinese medicine preparation for treating lung cancer |
| CN105055929A (en) * | 2015-07-19 | 2015-11-18 | 张乃智 | Traditional Chinese medicinal preparation for treating lung cancer |
| CN105213911A (en) * | 2015-10-30 | 2016-01-06 | 山东省立医院 | A kind of Chinese medicine composition for the treatment of pulmonary carcinoma |
| CN106728912B (en) * | 2017-01-06 | 2020-05-12 | 林丽珠 | Composition for treating lung cancer and application of composition for preparing medicine for treating lung cancer |
| CN107412635A (en) * | 2017-05-22 | 2017-12-01 | 何东良 | A kind of Chinese medicine composition and its preparation for treating lung cancer |
| CN107412675A (en) * | 2017-07-31 | 2017-12-01 | 王辉 | A kind of dissipating bind disappears knurl herbal composite and its preparation method and application |
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