CN104547810A - Traditional Chinese medicine preparation for treating lung cancer - Google Patents

Abstract

The invention discloses a traditional Chinese medicine preparation for treating lung cancer. The traditional Chinese medicine preparation is a decoction prepared from raw materials in parts by weight as follows: ginseng, Chinese angelica, pinellia ternate, poria cocos, largehead atractylodes rhizomes, radix asparagi, apricot kernel, radix asteris, pericarpium citri reticulatae, common coltsfoot flowers, grifola umbellate, fructus trichosanthis, stemona japonica, panax pseudo-ginseng, ligusticum wallichii, fritillaria, rhubarb, prunella vulgaris, radix astragali, red ochre, houttuynia cordata, scutellariae barbatae, hedyotis diffusa, fructus polygoni orientalis, achyranthes bidentata, barks of sago cycas, dendrobium nobile, centipedes, cistanche, rhizome anemarrhenae, pangolin scale, rhizoma dioscoreae bulbiferae and semen coicis. The traditional Chinese medicine preparation has the effects of blood replenishment, lung moistening, qi descending, phlegm dissolution, cough relief and improvement of the immunity of a human body, contributes to cure and recovery of lung cancer, is non-poisonous and harmless to the human body, good in stability, capable of treating both symptoms and root causes and low in price, and the cure rate reaches more than 95%.

Description

A kind of Chinese medicine preparation for the treatment of pulmonary carcinoma

technical fieldthe invention belongs to Chinese medicine technical field, be specifically related to a kind of Chinese medicine preparation for the treatment of pulmonary carcinoma.

background technologyalong with the development of society and the quickening of urbanization process, the life of people becomes very convenient, but living environment is but subject to serious impact, the healthy of people in the serious threats such as air pollution, food pollution, pollution of waterhead, add the bad life habits such as smoking, increasing people have changed pulmonary carcinoma, and the M & M due to pulmonary carcinoma increases the fastest, to become one of population health and the maximum malignant tumor of life threat.The many countries of immediate and mid-term all report that the M & M of pulmonary carcinoma all obviously increases, and male lung cancer M & M all accounts for first of all malignant tumor, and women's sickness rate accounts for second, and mortality rate accounts for second.At present, the treatment means of pulmonary carcinoma is still based on excision, but postoperative multiplex relapse and metastasis, and mortality rate is high; Secondly, though radiation and chemotherapy can kill cancerous cell, also grievous injury normal structure simultaneously, toxic and side effects is large, patient suffering's degree is strong; There is abundant Chinese medicine medical resource in China, and the side effect of Chinese medicine is little, without the need to standing the misery of operation and chemicotherapy, plays more and more important effect in prevention and therapy pulmonary carcinoma.

CN101549032 discloses a kind ofly to be had the pharmaceutical composition of antitumaous effect and is preparing the application in cancer therapy drug, this pharmaceutical composition comprises Spica Prunellae, Hedyotidis Diffusae, Herba Agrimoniae, Herba Ecliptae, Fructus Corni, there is nourishing kidney lung heat clearing, effect that heat clearing away eliminating stagnation is anticancer, has stronger suppression people to take the proliferation activity of cancerous cell SPC-A-1.

CN1057469 discloses a kind of anti-lung-cancer medicament, and this medicine comprises Cordyceps, Placenta Hominis, the Radix Stemonae, Bulbus Lilii, Radix Glycyrrhizae, the Radix Astragali, Radix Scutellariae, Radix Asparagi, Radix Ophiopogonis, Radix Platycodonis, has nourishing YIN and moistening the lung, improves effect of immunity.

CN1066943 discloses a kind of oral liquid for curing cancer, comprises Radix Scutellariae, Hedyotidis Diffusae, Radix Salviae Miltiorrhizae, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae Radix Astragali, Herba Ecliptae, Radix Curcumae, has effect of strengthening the body resistance, hard masses softening and resolving, blood circulation promoting and blood stasis dispelling.

CN101954022 discloses a kind of Chinese medicine composition being used for the treatment of pulmonary carcinoma, this pharmaceutical composition comprises the 19 taste Chinese medicines such as Radix Adenophorae (Radix Glehniae), Radix Asparagi, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Panacis Quinquefolii, Bulbus Fritillariae Cirrhosae, Folium Eriobotryae, Herba Scutellariae Barbatae and makes, and has effect of heat-clearing and toxic substances removing, dissolving blood stasis and detoxication.

Can find out that motherland's traditional medicine resource achieves good therapeutic effect to treatment pulmonary carcinoma aspect by above-mentioned disclosed patent documentation, but also there is area for improvement.

summary of the inventionthe object of this invention is to provide a kind ofly improve immunity of organisms, treating both the principal and secondary aspects of a disease, have no side effect, the Chinese medicine preparation of the treatment pulmonary carcinoma that cheap, cure rate is high, to make up the deficiencies in the prior art.

Solution of the present invention is based on motherland's medical science to the pathogeny of pulmonary carcinoma and the understanding and the Therapeutic Principle that improve immunity of organisms, with reference to ancient, modern pharmacological research achievement, treatment pulmonary carcinoma is had to the effect of healing and rehabilitation.

The present invention is prepared from by the raw material of following weight proportioning:

Radix Ginseng 15, Radix Angelicae Sinensis 15, the Rhizoma Pinelliae 15, Poria 15, the Rhizoma Atractylodis Macrocephalae 15, Radix Asparagi 15, Semen Armeniacae Amarum 15, Radix Asteris 10, Pericarpium Citri Reticulatae 15, Flos Farfarae 15, Polyporus 15, Fructus Trichosanthis 15, the Radix Stemonae 15, Radix Notoginseng 15, Rhizoma Chuanxiong 15, Bulbus Fritillariae Uninbracteatae 15, Radix Et Rhizoma Rhei 15, Spica Prunellae 15, the Radix Astragali 30, Haematitum 30, Herba Houttuyniae 30, Herba Scutellariae Barbatae 30, Hedyotidis Diffusae 30, Herba Polygoni Orientalis 30, Niu Gencao 30, Cycas revoluta skin 30, Herba Dendrobii 30, Scolopendra 5, Herba Cistanches 20, the Rhizoma Anemarrhenae 20, Squama Manis 20, Rhizoma Dioscoreae Bulbiferae 20, raw Semen Coicis 5.

By adding 3-5 times amount soak by water 1-2 hour after above-mentioned each component Homogeneous phase mixing, wait to naturally cool to 50 DEG C, leaching medicinal liquid, residue medicinal residues repeat to decoct with water twice again, and namely the medicinal liquid merged after filtering for three times obtains oral liquid medicine of the present invention.

Instructions of taking: every bu three times is oral, each 30ml.

Radix Ginseng in the present invention also claims the king of Sphallerocarpus gracilis, Herba Stellariae Saxatilis, BAICAO, herbaceos perennial, and happiness is shady and cool, and the root of Radix Ginseng is famous strong tonic; Sweet in the mouth, micro-hardship, warm in nature, flat, return spleen lung meridian, there is QI invigorating, admittedly take off, promote the production of body fluid, calm the nerves, effect of Fructus Alpiniae Oxyphyllae.

Radix Angelicae Sinensis also claims dryly to return, Radix Angelicae Sinensis, Radix Angelicae Gigatis, and sweet in the mouth, temperature, return liver, the heart, spleen channel, and its root can be used as medicine, and has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes effect of laxation.

The Rhizoma Pinelliae, has another name called ground literary composition, keeps field, belong to Arales, have drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, raw with the furuncle and phyma effect that disappears.

Poria, the dry sclerotia of On Polyporaceae Poria, sweet in the mouth, light, GUIXIN, lung, spleen, kidney channel, have promoting diuresis to eliminate damp pathogen, spleen invigorating, effect of mind calming, for edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, irritability, palpitation with fear insomnia.

The Rhizoma Atractylodis Macrocephalae, another name Rhizoma Atractylodis Macrocephalae, the winter Rhizoma Atractylodis Macrocephalae etc., belong to Compositae, [WTBX herbaceos perennial, bitter in the mouth, sweet, warm in nature, returns spleen, stomach warp; Be used as medicine with rhizome, have invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.

Radix Asparagi, the tuber of liliaceous plant Radix Asparagi, cold in nature, sweet and slightly bitter taste, has replenishing YIN and removing heat, effect of lung moistening nourishing kidney.For the disease such as control fever due to yin deficiency, lung abscess, quench one's thirst.Radix Asparagi contains asparagine, B-sitosterol, steroid saponin, the composition such as phlegmatic temperament, furfural derivatives.Radix Asparagi has hemocytes increasing, strengthens the effect of reticuloendothelial system phagocytic function and prolongation antibody life period.

Semen Armeniacae Amarum, also claims almond core, Fructus Pruni, returns lung, spleen, large intestine channel, have relieving cough and asthma, effect of relaxing bowel, be mainly used in cough due to consumptive disease.Main component amygdaloside can help body endotrypsin to digest the mucoprotein film of transparent sample of cancerous cell, and make the more accessible cancerous cell of leukocyte in body, and engulf cancerous cell, amygdaloside can kill cancerous cell by selectivity, and almost harmless to normal cell.

Radix Asteris, another name Chinese cabbage, Compositae, Aster, dry rhizome can be used as medicine, and has nourishing the lung to keep the adverse QI downward, the effect of stopping coughing and removing phlegm and diuresis.

Pericarpium Citri Reticulatae is the dry mature skin of rutaceae orange and variety thereof, bitter in the mouth, pungent, warm in nature, has regulating qi-flowing for strengthening spleen, effect of drying dampness to eliminate phlegm, for distension and fullness in the abdomen, and lack of appetite and vomiting, cough with copious phlegm.

Flos Farfarae, is the alabastrum of dicotyledon medicine feverfew Flos Farfarae, has nourishing the lung to keep the adverse QI downward, effect of preventing phlegm from forming and stopping coughing.

Polyporus, another name pig Poria, Rhizoma Anemones flaccidae Fructus Persicae, Aphyllophorales Polyporaceae Ramalina medicinal fungi.Its underground sclerotium black, various shapes are famous Chinese medicine, have diuresis harness the river swollen, improve immunity, antitumor effect.

Fructus Trichosanthis, another name medicine melon, the perennial climbing herb of Cucurbitaceae snake gourd, have antipyreticly to quench the thirst, diuresis, relieving cough and expelling phlegm, the antibacterial effect such as anticancer.

The Radix Stemonae, have another name called Herba delphinii grandiflori, mother-in-law woman grass, sweet, bitter, tepor, returns lung meridian, has antitussive, eliminates the phlegm, the effect of resisting pathogenic microbes.

Radix Notoginseng, has another name called Panax pseudoginseng Wall., Typhonium flagelliforme (Lodd.) Blume, Radix Notoginseng, herbaceos perennial, cures mainly spitting of blood, and spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling, and sweet and slightly bitter taste, property is put down, nontoxic.

Rhizoma Chuanxiong, has another name called large Rhizoma Chuanxiong, the rhizome of samphire Rhizoma Chuanxiong, gas giving off a strong fragrance, bitter in the mouth, pungent, returns liver, gallbladder, pericardium channel, can coronary artery dilator, increases coronary artery blood flow, improves the blood oxygen supply of cardiac muscle, and reduce the oxygen consumption of cardiac muscle; There is the effect of vitamin antagonist E shortage; Multiple bacillus can be suppressed; There are antihistaminic and choleretic effect.

Bulbus Fritillariae Uninbracteatae, herbaceos perennial, its bulb hyoscine, another name Herba Sonchi Oleracei, bitter flower, medicine are real, the merit of energy relieving cough and resolving phlegm, heat clearing away eliminating stagnation.Cure mainly phlegm heat cough, exogenous cough, cough due to yin deficiency, the few parched throat of expectorant, the diseases such as Huang is thick, lung abscess, acute mastitis, carbuncle pyogenic infections from tumour or sore, scrofula of coughing up phlegm.Modern pharmacology experiment proves, Bulbus Fritillariae Uninbracteatae has the effects such as antitussive, blood pressure lowering, raise blood sugar.

Radix Et Rhizoma Rhei, calls fragrant Radix Et Rhizoma Rhei, R.hoofshaped, general, raw army, bitter in the mouth, cold in nature, returns spleen, stomach, large intestine, liver, pericardium channel, has effects such as attacking stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances.

Spica Prunellae, other places nine Rhizoma Paridis, ferrum color grass, large headdress flower, improving eyesight of can relieving inflammation or internal heat, can control the effect such as conjunctival congestion and swelling pain, headache.It is liver heat removing, hepatoprotective " panacea ".Specially control order pearl nyctalgia, the vertigo.

The Radix Astragali, has another name called that Radix Astragali, hundred medicines are continuous, Sphallerocarpus gracilis, returns lung, spleen, liver, kidney channel, it has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.

Haematitum, have another name called must ball, red soil, blood teacher, be the Ore of oxide-based mineral bloodstone, bitter in the mouth, cold, can suppressing the hyperactive liver town inverse, cooling blood for hemostasis.Control eructation vomiting, dysphagia and regurgitation, asthma, infantile convulsion, spit blood, epistaxis, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, bleeding not during menses.

Herba Houttuyniae, also known as Cor Canitis grass, Herba Houttuyniae, acrid in the mouth, cold, return lung meridian.Heat-clearing and toxic substances removing, detumescence can treat skin ulcer, promoting urination to remove dampness, clearing away heat to cure dysentery, invigorating the stomach and promoting digestion, by the lung abscess, sore swollen toxin, hemorrhoidal hemorrhage, retention of heat in the spleen and stomach etc. of controlling excess-heat, pyretic toxicity, damp, disease heat are trouble.Modern pharmacology experiment shows, this product has the effect such as antibacterial, antiviral, raising immunity of organisms, diuresis.

Herba Scutellariae Barbatae is the dry herb of labiate Herba Scutellariae Barbatae, another name Aleuritopteris argentea (Gmel.) Fee, purple connects grass, acrid in the mouth, hardship, cold in nature, returns lung, liver, kidney channel, can heat-clearing and toxic substances removing, and blood stasis dispelling diuresis, for furuncle swelling toxin, laryngopharynx swelling and pain, falls and flutter the pain of injury, edema, jaundice, snake bite and insect sting.

Hedyotidis Diffusae, also claims Herba Hedyotidis Diffusae, is the whole herb with root of dicotyledon medicine Maguireothamnus speciosus Herba Hedyotidis Diffusae.Annually hang down loosely herbaceous plant without hair is very thin, can be used as medicine, have the effect of antitumor, anti-inflammation, raising immunity.

Herba Polygoni Orientalis is the fruit of polygonaceae plant smartweed, another name Fructus polygoni hydropiperis, water Herba Polygoni Orientalis, blood eliminating mass of can faling apart, removing food stagnancy pain relieving.For lump in the abdomen mass in the abdomen, goiter swells and ache, food stagnation does not disappear, epigastric distending pain.

Niu Gencao, also claims Radix Achyranthis Bidentatae, Radix Achyranthis Bidentatae, cattle stem, and ripe use can invigorating the liver and kidney, and strong waist knee joint, controls soreness of waist and knee joint, caused by liver and kidney deficiency, traumatic injury stasis of blood pain.

Cycas revoluta skin, namely from the bark that Cycas revoluta trunk peels, the whole year can adopt.Cycas revoluta is evergreen all the year round, the clean cunning of leatherleaf light, and Cycas revoluta not only ornamental value is high, also has good medical value, and Cycas revoluta is containing phenols, aminoacid and sugar; Its nature and flavor are sweet, light, flat, slightly poisonous; Cycas revoluta has effect of heat clearing away, hemostasis, dissipating blood stasis; Cure mainly dysentery, spit blood, have blood in stool, have a stomachache, hematuria, menorrhagia, treating swelling and pain by traumatic injury etc.

Herba Dendrobii, has another name called lofty or bottomless palpus, bracketplant, Lin Lan, Qian Nianrun, property slightly sweet flavor, micro-salty, cold, returns stomach, kidney, lung meridian, can reinforcing stomach reg fluid, and nourishing YIN and clearing away heat, loses for cloudy impairment of body fluid, xerostomia excessive thirst, and lack of appetite is retched, deficiency-heat after being ill, poor vision.

Scolopendra is Lu Sheng arthropod, also claims Gekko Swinhonis, centipede worm, warm in nature, and acrid in the mouth is poisonous.There is the function of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, apoplexy facial hemiparalysis, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, skin infection, scrofula, venom.

Herba Cistanches, another name rues greatly, Herba Cistanches, Herba Stellariae Saxatilis, have the good reputation of " desert Radix Ginseng ", there is high medical value, the rare Chinese medicine of Chinese tradition, Herba Cistanches sweet in the mouth, warm in nature, the effect such as there is kidney invigorating and YANG supporting, benefiting essence and marrow, blood enriching and dryness moistening, happy color are prolonged life.

The Rhizoma Anemarrhenae, also claims to connect female, L.Lucidus Turcz., bitter in the mouth, cold, returns lung, stomach, kidney channel, can clearing away heat-fire, nourshing Yin and drynsessmoistening prescription.Cure mainly calentura excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.

Squama Manis sheet, has another name called first sheet, Pseudobulbus Pholidotae Chinensis, scute sheet, according to pharmacopeia made, have invigorate blood circulation, stimulating milk secretion, detumescence, the effect such as evacuation of pus, for diseases such as galactostasis, carbuncle sore tumefacting virus, group's warp, arthralgia.

Rhizoma Dioscoreae Bulbiferae, also claims Antenoron filiforme herb, xanthate, Dioscorea bulbifera L., yellow dog head, feeble QI bitter in the mouth, can dissipating phlegm and resolving masses, cooling blood for hemostasis.For thyromegaly, tuberculous lymphadenitis, laryngopharynx swelling and pain, spits blood, spitting of blood, pertussis, cancerous protuberance; Furuncle is controlled in external.

Radix Glycyrrhizae, another name Herba Hedyotis cantonensis root, old, the sweet root of state, feeble QI, taste is sweet and special, cures mainly heat-clearing and toxic substances removing, expelling phlegm for arresting cough, gastral cavity abdomen etc.

Raw Semen Coicis, another name Semen Coicis, Semen Coicis, return spleen, lung, stomach warp, can promoting diuresis to eliminate damp pathogen, and inducing diuresis to remove edema, eliminating damp-heat, invigorating spleen to remove dampness, alleviates contracture, removing pus and relieving carbuncle.

Clinical drug of the present invention uses result to show, have benefiting blood and regulating blood circulation, nourishing the lung to keep the adverse QI downward, effect of stopping coughing and removing phlegm, enhancing body immunity, has effect of healing and rehabilitation to pulmonary carcinoma,, good stability, treating both the principal and secondary aspects of a disease harmless to human non-toxic, cheap, cure rate more than 95%.

Detailed description of the invention

Embodiment one

A kind of Chinese medicine preparation for the treatment of pulmonary carcinoma, by Chinese crude drug Radix Ginseng 15, Radix Angelicae Sinensis 15, the Rhizoma Pinelliae 15, Poria 15, the Rhizoma Atractylodis Macrocephalae 15, Radix Asparagi 15, Semen Armeniacae Amarum 15, Radix Asteris 10, Pericarpium Citri Reticulatae 15, Flos Farfarae 15, Polyporus 15, Fructus Trichosanthis 15, the Radix Stemonae 15, Radix Notoginseng 15, Rhizoma Chuanxiong 15, Bulbus Fritillariae Uninbracteatae 15, Radix Et Rhizoma Rhei 15, Spica Prunellae 15, the Radix Astragali 30, Haematitum 30, Herba Houttuyniae 30, Herba Scutellariae Barbatae 30, Hedyotidis Diffusae 30, Herba Polygoni Orientalis 30, Niu Gencao 30, Cycas revoluta skin 30, Herba Dendrobii 30, Scolopendra 5, Herba Cistanches 20, the Rhizoma Anemarrhenae 20, Squama Manis 20, Rhizoma Dioscoreae Bulbiferae 20, raw Semen Coicis 5 compatibility, 3 times amount soak by water is added 1.5 hours by after above-mentioned each component Homogeneous phase mixing, wait to naturally cool to 50 DEG C, leaching medicinal liquid, residue medicinal residues repeat to decoct with water twice again, namely the medicinal liquid merged after filtering for three times obtains oral liquid medicine of the present invention, every bu three times is oral, each 30ml, positive effect is had to treatment pulmonary carcinoma.

Clinical trial:

Case selection

Patient age is in 19-69 year, men and women does not limit, and signature enters clinical research Informed Consent Form, meet pulmonary cancer diagnosis diagnostic criteria and TCM syndrome diagnostic criteria also applicable radiotherapy person, physical situation is fair, and estimation can be survived more than 3 months, pulmonary carcinoma II phase, III phase and IV phase, non-pregnant or women breast-feeding their children, non-allergic constitution, can include alternative case in.

Excluded cases standard: 1. intentionally, liver, the serious disease patient such as kidney, and function serious hindrance person, psychotic;

2. row excision, radiocurable patients with lung cancer, is carrying out radiotherapy or end of chemotherapy less than 2 months persons; 3. allergic constitution or irritated to multi-medicament, the age is below 18 one full year of life or 70 one full year of life above person.

The present invention includes 500 routine patients altogether in, its age 19-60 year between, wherein treatment group 250 example, matched group 250 example.The treatment group mean age is 43.8 years old, and the matched group mean age is 44.7 years old, patient course of disease 1-3, two groups of data are through statistical procedures, between two groups in age, sex, smoking, drink, zero difference in body weight, schooling etc., without statistics objection, there is comparability.

Administrations

Treatment group: treatment group patient takes medicinal liquid prepared by the embodiment of the present invention one, and each 30ml, every bu is taken for 3 times, and Time of Administration is 2 months.

Matched group: take Diamond blunt (Yicun Pharmaceutical Co., Ltd., Jiangxi's system), a 30ml, 3 times on the one, Time of Administration is 2 months.

Two groups of patient medication dosage are all consistent with the time, and must not take the medicine damaging pulmonary treatments period patient.Enjoin patient to take a good rest simultaneously, keep mood optimistic, keep good living habit, rational diet.

Observation index:

Comprehensive therapeutic effect: its criterion with reference to 2002 Ministry of Health of the People's Republic of China " Chinese medicine composition Clinical Researches of New Drugs guideline (trying) " criterion.

1. complete incidence graph (CR): through X sheet or/and fibre bronchus mirror, focus all absorbs, and maintain more than 4 weeks persons.

2. partial rcsponse (PR): focus reduces >=and 50%, and maintain more than 4 weeks persons.

3. stable (NC): focus reduces less than 50% or expands less than 25%.

4. progressive stage (PD): focus expands 25% before comparatively treating.

Effective percentage=(CR+PR)/treatment group number of cases × 100%

Statistical procedures

The statistical analysis of all data all adopts SPSS19.0 statistical analysis software to calculate.All statistical test all adopt bilateral to detect, and P<0.05 has statistical significance by being considered to checked differentiation, and P <0.01 will be considered to significance statistical significance.Measurement data adopts mean ± standard deviation (x ± S) to carry out statistics and describes.

The contrast of result of the test two groups of Patient Global's curative effects

Table 1

Group	Complete incidence graph (CR)	Partial rcsponse (PR)	Stable (NC)	Progressive stage (PD)
					Treatment group	205	40	5	0
Matched group	170	35	45	0

By table 1 treatment group and matched group more known, patient treats by taking medicine of the present invention, and itself CR and PR is all apparently higher than matched group, and NC is starkly lower than matched group, to treatment pulmonary carcinoma reach good therapeutic effect at short notice.

Embodiment two

This Chinese medicine preparation has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.

Animal acute toxicity test:

Medicine: Chinese medicine decoction of the present invention, tests front distilled water and carries out 10 times of dilutions, matching while using.

Toxicity: select 20 ~ 25 grams of mices 30 (purchased from Shanghai Si Laike animal center), male and female are not limit, by 0.5ml/ dosage gastric infusion, early, middle and late each once, it is dead that successive administration observes 10 days none examples of animal; Subacute toxicity test has also been done in this experiment.Result shows: decoction of the present invention is by after above-mentioned dosed administration, and every Index for examination and histopathologic slide are showed no any obvious exception.

Embodiment three

Model case is as follows:

1. section certain, man, 67 years old, patient's readme has smoking history, early stage appearance is interrupted cough, the symptom that slight breast is suppressed, later stage disease is deepened, cough round the clock, often there is the phenomenon of hemoptysis, appetite reduces half health and day by day becomes thin, weight loss is obvious, continue 5 years, this treatment by Chinese herbs is got after examining, be decocted in water for oral dose and take for three times on the one, period in a medicine must not exhort smoking, take a good rest, continuous use is after 1 month, disease obviously alleviates, cough oligemia, after continuing to take 5 months, no longer there is the phenomenon of hemoptysis, body weight increases, the mental status is clearly better, without chest pain sense.

2. Cao, man, 19 years old, students, accompany medical with household, and patients symptomatic is more than for coughing,, there is symptom uncomfortable in chest, out of breath in hoarseness, questions closely lower readme smoking history 1 year; get this treatment by Chinese herbs often, and be decocted in water for oral dose three sub-services every day, and after January, symptom is obviously alleviated; no longer occur symptom uncomfortable in chest, out of breath, after continuing to take 1 month, without the phenomenon of cough; condition, exhorting in the future must not smoking again.

3. Wang, man, 32 years old, height 180CM, body weight 62KG, patient is engaged in underground work for many years, and body weight is partially light, and time medical, cough is more than, apoplexy due to phlegm has the blood streak, out of breath, uncomfortable in chest, take temperature at 38 DEG C, hoarseness of speaking, weak, get this treatment by Chinese herbs, the bu that is decocted in water for oral dose is taken for three times, and after 2 months, cough alleviates, the accidental blood streak of apoplexy due to phlegm, continue to take the mental status after 4 months and greatly take a turn for the better, apoplexy due to phlegm is without the blood streak, weight recovery is normal, is in continue to recuperate transference cure after half a year, and health is fully recovered.

4. Zhang, female, 35 years old, do manual work in factory, be engaged in the work of medal polish, patient's readme starts after working 1 month to occur cough, dizzy, uncomfortable in chest symptom, after 3 months, symptom deepens to occur that cough is more than, hemoptysis, chest pain, come to go to a doctor so quit job, three oral the treatments by Chinese herbs of every bu, after 2 months, cough alleviates, without hemoptysis phenomenon, continue to take without chest pain sense after 2 months, condition, exhort and can not be engaged in this type of work more in the future.

Note: patient is during medication treatment, and should note recuperation, take exercise in right amount, irritable food of must not taking food, absolutely no smoking, should keep good work and rest custom.

Above-mentioned each Chinese medicine that the present invention adopts makes compatibility mutually, can play its collaborative effect of curing the disease, have the usefulness that drug effect is mutually promoted between each composition of raw material of Chinese medicine used; Follow up a case by regular visits to patient outcomes in time clinically, invented this Chinese medicine, cure rate reaches more than 95 percent.

Claims (1)

1. treat a Chinese medicine preparation for pulmonary carcinoma, it is characterized in that, described Chinese medicine preparation is prepared from by following raw material by weight ratio:

Radix Ginseng 15, Radix Angelicae Sinensis 15, the Rhizoma Pinelliae 15, Poria 15, the Rhizoma Atractylodis Macrocephalae 15, Radix Asparagi 15, Semen Armeniacae Amarum 15, Radix Asteris 10, Pericarpium Citri Reticulatae 15, Flos Farfarae 15, Polyporus 15, Fructus Trichosanthis 15, the Radix Stemonae 15, Radix Notoginseng 15, Rhizoma Chuanxiong 15, Bulbus Fritillariae Uninbracteatae 15, Radix Et Rhizoma Rhei 15, Spica Prunellae 15, the Radix Astragali 30, Haematitum 30, Herba Houttuyniae 30, Herba Scutellariae Barbatae 30, Hedyotidis Diffusae 30, Herba Polygoni Orientalis 30, Niu Gencao 30, Cycas revoluta skin 30, Herba Dendrobii 30, Scolopendra 5, Herba Cistanches 20, the Rhizoma Anemarrhenae 20, Squama Manis 20, Rhizoma Dioscoreae Bulbiferae 20, raw Semen Coicis 5;

Described Chinese medicine preparation preparation method comprises the steps:

1) 3-5 times amount soak by water 1-2 hour will be added after above-mentioned each component Homogeneous phase mixing;

2) wait to naturally cool to 50 DEG C, leaching medicinal liquid;

3) remain medicinal residues to repeat again to decoct with water twice;

4) namely the medicinal liquid merged after filtering for three times obtains oral liquid medicine of the present invention.