CN107823586A - A kind of decoction medicine and preparation method that can effectively treat recurrent oral ulceration - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of decoction medicine that can effectively treat recurrent oral ulceration according to the understanding mechanism of Chinese traditional treatment recurrent oral ulceration, each component and its mass parts ratio of the medicine are as follows：10~16g of Rhizoma soulieae vaginatae, 3~15g of licorice, 15~28g of nervos brake herb, 5~16g of manyleaf meadowure rhizome and root, 3~10g of radix scutellariae, 6~10g of henry hemsleya root, 5~16g of west Szechwan pyrethrum flower, 15~26g of yunnan cowpea root, 3~7g of the coptis, 10~25g of wolf's milk, 10~15g of red halloysite, 10~16g of folium callicarpae pedunculatae, 1~5g of catechu, 3~12g of rhizoma zingiberis, 3~10g of Panax Japonicus Var. Major, 25~55g of scandent hedyotis herb, 10~16g of selenitum, 9~16g of dandelion；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of decoction medicine and preparation method that can effectively treat recurrent oral ulceration

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of decoction medicine that can effectively treat recurrent oral ulceration Thing, the decoction medicine particularly used for Blood of Patients with Recurrent Oral and the field of preparation method.

Background technology

According to data：Recurrent aphthous ulcer（recurrent oral ulcer）Also known as RAU （recurrent aphthae）, be most common ulcer diseases in oral mucosal disease, the cause of disease is complicated, more with it is immune, hereditary, Systemic disease, infection, environment（Psychology, life, work, social environment）It is relevant etc. factor.Illness rate is typically recognized in crowd For more than 10%, men and women, old and young can be betided, with young and middle-aged most common.Recurrent oral ulceration has self limiting, can with self-healing, Any position of mucous membrane of mouth can be betided, common with lip, cheek, tongue, severe patient can involve pharyngeal mucous membrane.Many patients with The extension of the course of disease, ulcer area increase, number increases, and pain aggravates, and healing stage extends, and interval shortening etc., influences to feed With speak.

Clinical manifestation：

1. minor aphtha：It is sensitive or the congested area of needle point sample size occur from the beginning of lesion, formed in a short time diameter 2~ 4mm, circular or ellipse, the shallow aphtha of clear border.Center micro-pits, surface are covered with one layer of faint yellow pseudomembrane, ulcer week It is in blush shape to enclose mucous membrane hyperemia, and its substrate is laid one's hand on not hard.Ulcer number is generally 2~3.Ulcer has more violent burning after being formed Cusalgia, especially with obvious at the tip of the tongue.When contacting food excitatory more very.Typically without constitutional symptom.

2. rash sample aphtha：Also known as stomatitis type aphtha.This type is except ulcer is small, number is more（Up to 20~30）Outside, it is remaining with it is light The performance of type aphtha is similar.For Sucralfate widely distributed, mucous membrane is congested obvious.Have acutely and with headache, heating, regional nodes The symptoms such as enlargement.

3. periglandular aphtha：Also known as Periadenitis mucous membrane periadenitis or huge aphtha, it is various middle most serious One type.Ulcer often single generation, 2 or more than 2 persons it is rare.Lip inner side and bicker area mucous membrane are apt to occur in, can also be occurred in tongue palate The positions such as bow, soft palate.From the beginning of when ulcer it is identical with minor aphtha, but its diameter is gradually extended to 1~2cm, and to Deep Development To mucous membrane gland.Ulcer can be aubergine, and edge is irregular, is swelled in flap, concavity, and shape is like " crater ".Bottom is uneven, micro- Firmly, in brief summary nodular.Blush is obvious around ulcer.Part has severe pain and can be with whole bodies such as regional glandular enlargement, heatings Symptom.The course of disease is often more than more than the moon, and elder was up to 1 year.Scar is left more afterwards, and severe patient can form tissue defect or deformity.

So, it is art technology with regard to how to find a kind of Chinese medicine composition that can effectively treat recurrent oral ulceration The problem of personnel are urgently to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, on treatment recurrent oral ulceration, people gradually appreciate The advantages of Chinese traditional treatment recurrent oral ulceration, and good effect, advantage, the pin such as quick, toxic side effect is small over the course for the treatment of To the present situation of existing western medical treatment recurrent oral ulceration, the purpose of the present invention is to be that recurrent can effectively be treated by providing one kind The decoction medicine of canker sore, to solve the problems, such as that Blood of Patients with Recurrent Oral is got well early.The medicine is with common Chinese medicine be raw material, by selecting rational medicine and mass parts ratio, can effectively treat above-mentioned recurrent oral ulceration.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：Recurrence can effectively be treated by providing one kind The decoction medicine and preparation method of property canker sore, it is characterised in that each component and mass parts of the medicine are than following institute Show：

10~16g of Rhizoma soulieae vaginatae, 3~15g of licorice, 15~28g of nervos brake herb, 5~16g of manyleaf meadowure rhizome and root, 3~10g of radix scutellariae, henry hemsleya root 6~10g, 5~16g of west Szechwan pyrethrum flower, 15~26g of yunnan cowpea root, 3~7g of the coptis, 10~25g of wolf's milk, 10~15g of red halloysite, purple 10~16g of pearl leaf, 1~5g of catechu, 3~12g of rhizoma zingiberis, 3~10g of Panax Japonicus Var. Major, 25~55g of scandent hedyotis herb, 10~16g of selenitum, Pu Public 9~16g of English.

A kind of decoction medicine and preparation method that can effectively treat recurrent oral ulceration, it is characterised in that the medicine Each component and mass parts than as follows：

11~15g of Rhizoma soulieae vaginatae, 5~13g of licorice, 18~25g of nervos brake herb, 6~15g of manyleaf meadowure rhizome and root, 5~9g of radix scutellariae, henry hemsleya root 7 ~9g, 6~15g of west Szechwan pyrethrum flower, 18~23g of yunnan cowpea root, 4~6g of the coptis, 11~22g of wolf's milk, 11~13g of red halloysite, Japanses beauty-berry 11~15g of leaf, 2~4g of catechu, 5~11g of rhizoma zingiberis, 5~9g of Panax Japonicus Var. Major, 30~48g of scandent hedyotis herb, 11~14g of selenitum, dandelion 10~15g.

A kind of decoction medicine and preparation method that can effectively treat recurrent oral ulceration, it is characterised in that the medicine Each component and mass parts than as follows：

Rhizoma soulieae vaginatae 14g, licorice 12g, nervos brake herb 22g, manyleaf meadowure rhizome and root 14g, radix scutellariae 8g, henry hemsleya root 8g, west Szechwan pyrethrum flower 14g, mountain horse Beans root 20g, coptis 5g, wolf's milk 20g, red halloysite 12g, folium callicarpae pedunculatae 14g, catechu 3g, rhizoma zingiberis 10g, Panax Japonicus Var. Major 8g, scandent hedyotis herb 42g, selenitum 13g, dandelion 13g.

A kind of decoction medicine and preparation method that can effectively treat recurrent oral ulceration, it is characterised in that methods described Comprise the following steps to be prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 45min, then again by soaked medicine and soak medicine Clarified solution be put into the lump in marmite, injected medicine 63mm cold boiling water carry out first time high heat decoction, wait decoct arrive 15min When, turn slow fire and boil 35 min, leaching decoction；2. the tepor boiling water that medicine 60mm was re-injected in the dregs of a decoction carries out second of intense fire Decoct, when 10min is arrived in decoction, turn slow fire and boil 30 min, leaching decoction；It is condensed into 3. decoction twice is mixed in 50% Decoction 410ml（Milliliter）.

A kind of decoction medicine and preparation method that can effectively treat recurrent oral ulceration, it is characterised in that described to take Method is：The herb liquid prepared was taken with one day, one portion per day, morning and evening sub-service, dosage 205ml（Milliliter）/ time, before meals Half an hour takes（Avoid eating raw food and maror）.7 days are a course for the treatment of, 1~2 course for the treatment of of taking medicine, ulcer healing, and symptom all disappears Lose, disease obtains recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Rhizoma soulieae vaginatae, nature and flavor：It is bitter, cool, have relieving restlessness that clears away heart-fire, it is clearing heat and detoxicating the effect of, for treat pharyngitis, conjunctivitis, stomatitis, Osteopyrexia and fever, nervous palpitaition, dysphoria, bacillary dysentery, enteritis, ulcerative carbuncle pyogenic infections;

Licorice, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, For treating the thin face Huang of burnout deficiency of food, flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat swell Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning；

Nervos brake herb, nature and flavor：It is sweet, cool, there is the effect of heat-clearing, dampness removing, wind-dispelling, removing toxic substances, for treating icteric hepatitis, rushing down The diseases such as dysentery, oedema, stranguria with turbid discharge, irregular menstruation, tonsillitis, burn；

Manyleaf meadowure rhizome and root, nature and flavor：Cold in nature, bitter, there is the effect of heat-clearing and damp-drying drug, removing toxic substances, for treating dysentery, enteritis, infectiousness liver The diseases such as inflammation, flu, measles, carbuncle swells boil, conjunctivitis；

Radix scutellariae, nature and flavor：It is bitter, cold in nature, have clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, it is antiabortive the effect of, for treating lung heat cough Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis illness；

Henry hemsleya root, nature and flavor：It is bitter, puckery, cold in nature, there is the effect of clearing heat and detoxicating, analgesic, for treat bacillary dysentery, enteritis, gastritis, Sphagitis, parotitis, periodontitis, epidemic conjunctivitis, tonsillitis, high fever, urinary tract infections；

West Szechwan pyrethrum flower, nature and flavor：Cold in nature, bitter, there is promoting blood circulation, clearing damp, anti-inflammatory, the effect of relieving pain, for treating traumatic injury, damp and hot Deng disease；

Yunnan cowpea root, nature and flavor：It is bitter, cold, there is the effect of asking thermal detoxification, swelling and pain relieving, relieving sore-throat, for treating acute toothache, larynx Bitterly, pulmonary tuberculosis, after abdominal distension, stomachache, constipation, sore, children's measles residual poison not to the utmost, bruise arthralgia；

The coptis, nature and flavor：It is bitter, cold, there is the effect of purging intense heat, eliminating dampness, removing toxic substances, desinsection, row heat toxin, typhoid fever, excess heat during for treating Vexed, feeling of fullness vomit inverse, bacillary dysentery, heat rush down stomachache, lung knot by, tell, be defeated in battle, lower blood, quench one's thirst, infantile malnutrition due to digestive disturbances or intestinalparasites, roundworm disease, pertussis, throat swell Bitterly, pinkeye, aphtha, skin sore, eczema, the burning hot wound of soup；

Wolf's milk, nature and flavor：It is acrid flavour, mild-natured, there is the effect of clearing heat and detoxicating, cooling blood and hemostasis, removing dampness through diuresis and removing jaundice, for treat dysentery, Diarrhea, spitting of blood, hematuria, have blood in stool, uterine bleeding, boil carbuncle swells, jaundice with damp-heat pathogen；

Red halloysite, nature and flavor：It is sweet, sour, puckery, warm-natured, there is the effect of puckery intestines, hemostasis, myogenic sore, it is long for treating chronic diarrhea Under dysentery, fecal blood, uterine bleeding band, sore burst for a long time and does not holds back, wet sore pus contamination are controlled outside；

Folium callicarpae pedunculatae, nature and flavor：It is cool in nature, bitter, puckery, there is the effect of astringing to arrest bleeding, clearing heat and detoxicating, belong to hemostatic astringent hemostatic, It is preferable for various haemorrhages caused by treating blood-head, especially with alimentary canal, hemorrhage from respiratory tract effect, skin sore is controlled outside, poisonous snake stings The disease such as wound, heat toxin abscess of throat, red eye, swell pain；

Catechu, nature and flavor：It is bitter, puckery, be slightly cold, there is the effect of hygroscopic myogenic sore, for treating unhealing ulcer, eczema, aphtha, falling Flutter grieved, traumatism and bleeding；

Rhizoma zingiberis, nature and flavor：Acrid flavour, property heat, have the effect of warming spleen and stomach for dispelling cold, Back to Yang Tongmai, Wenfei of drink, cold for treating gastral cavity abdomen Bitterly, vomiting, diarrhea, yang depletion faint inverse, cold drink breath with cough, numbness and ache of cold dampness；

Panax Japonicus Var. Major, nature and flavor：It is bitter, sweet, be slightly cold, there is the effect of tonifying lung, yin-nourishing, active, hemostasis, for treating deficiency of both qi and yin, tired Hot thirsty, cough due to consumptive disease, injury from falling down, arthralgia, hemoptysis, haematemesis, traumatism and bleeding；

Scandent hedyotis herb, there is the effect of anti-inflammatory, symplectic bone, for treating the diseases such as pneumonia, branch gas bamboo inflammation, stomatitis, pulmonary tuberculosis, fracture；

Selenitum, nature and flavor：It is salty, cold, warm, it is nontoxic, there is the effect of replenishing the vital essence and removing heat, for treating high fever polydipsia, headache due to yin-deficiency, the heart Lower turgor, hot eyes Grating pains；

Dandelion, nature and flavor：It is bitter, sweet, cold, there is the effect of clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia, swollen for treating furunculosis Poison, acute mastitis, scrofula, hot eyes, pharyngalgia, lung carbuncle, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.

Medicine of the present invention is the principle based on Chinese traditional treatment recurrent oral ulceration, from the disease according to recurrent oral ulceration Reason mechanism and pharmacological action are thought：With regard to recurrent oral ulceration, each raw material herbal medicine efficacy in medicine provided by the present invention is total to Play, have good therapeutic effect to above-mentioned disease.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned recurrent oral ulceration, using the formula The medicine effect of preparation is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the present invention Embodiment be described in further detail：

Embodiment 1：

A kind of decoction medicine that can effectively treat recurrent oral ulceration, it is characterised in that each component and matter of the medicine Part is measured than as follows：

Rhizoma soulieae vaginatae 14g, licorice 12g, nervos brake herb 22g, manyleaf meadowure rhizome and root 14g, radix scutellariae 8g, henry hemsleya root 8g, west Szechwan pyrethrum flower 14g, mountain horse Beans root 20g, coptis 5g, wolf's milk 20g, red halloysite 12g, folium callicarpae pedunculatae 14g, catechu 3g, rhizoma zingiberis 10g, Panax Japonicus Var. Major 8g, scandent hedyotis herb 42g, selenitum 13g, dandelion 13g.

Embodiment 2：

A kind of decoction medicine that can effectively treat recurrent oral ulceration, it is characterised in that each component and matter of the medicine Part is measured than as follows：

Rhizoma soulieae vaginatae 15g, licorice 13g, nervos brake herb 25g, manyleaf meadowure rhizome and root 15g, radix scutellariae 9g, henry hemsleya root 9g, west Szechwan pyrethrum flower 15g, mountain horse Beans root 23g, coptis 6g, wolf's milk 22g, red halloysite 13g, folium callicarpae pedunculatae 15g, catechu 4g, rhizoma zingiberis 11g, Panax Japonicus Var. Major 9g, scandent hedyotis herb 48g, selenitum 14g, dandelion 15g.

Embodiment 3：

A kind of decoction medicine that can effectively treat recurrent oral ulceration, it is characterised in that each component and matter of the medicine Part is measured than as follows：

Rhizoma soulieae vaginatae 16g, licorice 15g, nervos brake herb 28g, manyleaf meadowure rhizome and root 16g, radix scutellariae 10g, henry hemsleya root 10g, west Szechwan pyrethrum flower 16g, mountain Horsebean root 26g, coptis 7g, wolf's milk 25g, red halloysite 15g, folium callicarpae pedunculatae 16g, catechu 5g, rhizoma zingiberis 12g, Panax Japonicus Var. Major 10g, reason lung Dissipate 55g, selenitum 16g, dandelion 16g.

Model case

Through clinical conditions Blood of Patients with Recurrent Oral totally 1247, the age is 720, only 527 of more than 33 years old For less than 33 years old.1038 to be fully recovered in 1247 patients, effective 165, invalid 44.Total effective rate is up to 96.5%.

Claims (3)

1. A kind of 1. decoction medicine that can effectively treat recurrent oral ulceration, it is characterised in that each component of the medicine and Its mass parts is than as follows：

   10~16g of Rhizoma soulieae vaginatae, 3~15g of licorice, 15~28g of nervos brake herb, 5~16g of manyleaf meadowure rhizome and root, 3~10g of radix scutellariae, henry hemsleya root 6~10g, 5~16g of west Szechwan pyrethrum flower, 15~26g of yunnan cowpea root, 3~7g of the coptis, 10~25g of wolf's milk, 10~15g of red halloysite, purple 10~16g of pearl leaf, 1~5g of catechu, 3~12g of rhizoma zingiberis, 3~10g of Panax Japonicus Var. Major, 25~55g of scandent hedyotis herb, 10~16g of selenitum, Pu Public 9~16g of English.
2. 2. the decoction medicine according to claim 1 that can effectively treat recurrent oral ulceration, it is characterised in that the medicine The each component and its mass parts of thing are than as follows：

   11~15g of Rhizoma soulieae vaginatae, 5~13g of licorice, 18~25g of nervos brake herb, 6~15g of manyleaf meadowure rhizome and root, 5~9g of radix scutellariae, henry hemsleya root 7 ~9g, 6~15g of west Szechwan pyrethrum flower, 18~23g of yunnan cowpea root, 4~6g of the coptis, 11~22g of wolf's milk, 11~13g of red halloysite, Japanses beauty-berry 11~15g of leaf, 2~4g of catechu, 5~11g of rhizoma zingiberis, 5~9g of Panax Japonicus Var. Major, 30~48g of scandent hedyotis herb, 11~14g of selenitum, dandelion 10~15g.
3. 3. the decoction medicine that can effectively treat recurrent oral ulceration according to claim 1 to 2, it is characterised in that institute The each component and its mass parts of medicine are stated than as follows：

   Rhizoma soulieae vaginatae 14g, licorice 12g, nervos brake herb 22g, manyleaf meadowure rhizome and root 14g, radix scutellariae 8g, henry hemsleya root 8g, west Szechwan pyrethrum flower 14g, mountain horse Beans root 20g, coptis 5g, wolf's milk 20g, red halloysite 12g, folium callicarpae pedunculatae 14g, catechu 3g, rhizoma zingiberis 10g, Panax Japonicus Var. Major 8g, scandent hedyotis herb 42g, selenitum 13g, dandelion 13g.