CN104758900A - Traditional Chinese medicine for treating acute pancreatitis - Google Patents
Traditional Chinese medicine for treating acute pancreatitis Download PDFInfo
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- CN104758900A CN104758900A CN201510155166.5A CN201510155166A CN104758900A CN 104758900 A CN104758900 A CN 104758900A CN 201510155166 A CN201510155166 A CN 201510155166A CN 104758900 A CN104758900 A CN 104758900A
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Abstract
The invention relates to a traditional Chinese medicine for treating acute pancreatitis. The traditional Chinese medicine is prepared from the following raw pharmaceutical materials in parts by weight: 15 parts of bupleurum root, 10 parts of fructus aurantii, 10 parts of citrus aurantium, 10 parts of radix scutellariae, 12 parts of radix paeoniae alba, 10 parts of prepared pinellia tuber, 6 parts of prepared rhubarb root, 15 parts of red date and 3 parts of ginger. Proved by clinical trials, the traditional Chinese medicine can be used for treating acute pancreatitis safely and effectively.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of acute pancreatitis.
Background technology
Acute pancreatitis is that Different types of etiopathogenises causes pancreatin to activate, with the reaction of pancreas local inflammation for principal character, companion or the disease changed without other organ dysfunction, it is one of common clinically acute abdomen, Etiological is biliary diseases, eating and drinking too much at one meal, excessive drinking etc., and its sickness rate rises year by year along with constantly heightening of living standard, and its course of disease is dangerous, complication is many, case fatality rate is high, and its mechanism is not illustrated completely.There is no the name of disease of " pancreatitis " in motherland's medical science, but ancient literature has a large amount of discussion similar with pancreatitis symptom etc., " abdominal distention fullness in the chest, gastral cavilty is when pained, and two side of body, swallows diaphragm obstructed, and epigastralgia also." belong to categories such as motherland's medical science " stomachache " " epigastralgia " " gastric abscesss " according to its genius morbi.Clinically mainly to increase as main manifestations with acute severe stomachache, Nausea and vomiting, pancreatin.
Medical material present Research involved in the present invention is as follows:
Smoke Radix Bupleuri [another name], Asia puecon recklessly, mountain dish, eat grass, faggot.[source] this product is the dry root of umbelliferae bupleurum or Radix Bupeuri Scorzonerfolii..Different by character, practise title " Radix Bupleuri " and " Radix Bupleuri Scorzonerifolii " respectively.Spring, Qiu Erji excavate, removing stem and leaf and silt, dry.[nature and flavor] are bitter, are slightly cold.[return through] returns liver, gallbladder meridian.[function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.The dry rhizome of [attention] bigleaf thorowax root, the close raw link in surface, poisonous, Radix Bupleuri can not be worked as and use.[extracts] " China's book on Chinese herbal medicine ".
The Rhizoma Pinelliae [another name] the SANYE Rhizoma Pinelliae, SANYE are old, three step jumpings, numb semen myristicae, swallow tail, civilian, water is beautiful.[source] this product is the dry tuber of the aroid Rhizoma Pinelliae.Summer, Qiu Erji excavate, and clean, and removing crust and fibrous root, dry.[nature and flavor] are pungent, temperature; Poisonous.[return through] returns spleen, stomach, lung meridian.[function cures mainly] drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] deficiency of YIN cough caused by dryness, Tianjin wound are thirsty, blood disorder and dry phlegm person prohibit clothes, the careful clothes of anemia of pregnant woman.Should not with Aconitum medical material with using.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Zingiberis Recens [another name] Rhizoma Zingiberis Recens.[source] this product is the fresh rhizome of zingiber.Autumn, season in winter two excavate, removing fibrous root and silt.[nature and flavor] are pungent, tepor.[return through] returns lung, spleen, stomach warp.[function cures mainly] induces sweat cold expelling, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing.For anemofrigid cold, gastrofrigid vomiting, cold-phlegm is coughed.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] food Rhizoma Zingiberis Recens is of a specified duration, and accumulated heat suffers from order.All sick hemorrhoid people polyphagia are held concurrently wine, vertically send out very speed.Carbuncle skin ulcer people polyphagia is then raw dislikes meat.[extracts] " China's book on Chinese herbal medicine ".
Fructus Jujubae [another name] [source] this product is the dry mature fruit of Rhamnaceae jujube Fructus Jujubae.Gather during fruit maturation in autumn, dry.Its root, bark are also used as medicine, and can adopt at any time.[nature and flavor] are sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.For insufficiency of the spleen lack of appetite, weak loose stool, woman hysteria.Antiinflammatory, hemostasis, antidiarrheal.For tracheitis, enteritis, dysentery, metrorrhagia; Traumatic hemorrhage is controlled in external.Circulation of qi promoting, invigorates blood circulation, regulating menstruation.For menoxenia, redly to collapse, leucorrhea.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[attention] all damp-phlegm, stagnant, tooth disease, worm patient, all unsuitable.Epigastric oppression, fullness in the epigastrium and abdomen vomiter avoids it.Polyphagia wind symptom, spleen is instead by sick.[extracts] " China's book on Chinese herbal medicine ".
Radix Scutellariae [another name] Radix Scutellariae, scutellaria tea, tsuchikane tea root.[source] this product is the dry root of labiate Radix Scutellariae.Spring, Qiu Erji excavate, and removing fibrous root and silt, hit rough bark after solarization, dry.[nature and flavor] are bitter, cold.[return through] returns lung, gallbladder, spleen, large intestine, small intestine meridian.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.[usage and dosage] takes orally: decoct soup, 3-9g.[attention] Fructus Corni, Os Draconis make for it.Dislike Semen allii fistulosi.Fear cinnabar, Paeonia suffruticosa, Rhizoma et radix veratri (Radix Rhizoma Veratri).[extracts] " China's book on Chinese herbal medicine ".
Fructus Aurantii Immaturus [source] this product is the dry young fruit of rutaceae Citrus aurantium Linn. and variety or Fructus Citri sinensis.5 ~ June collects the fruit from falling, and removing impurity, be two halves from middle part crosscut, dry or cold drying, smaller directly dries or cold drying.[nature and flavor] are bitter, pungent, sour, temperature.[return through] returns spleen, stomach warp.[function cures mainly] dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Stop in stagnant, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest; Gastroptosis, proctoptosis, uterine prolapse.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] anemia of pregnant woman is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
The Radix Paeoniae Alba [another name] Radix Paeoniae.[source] this product is the dry root of ranunculaceae plant Radix Paeoniae.Summer, Qiu Erji excavate, and clean, and remove end to end and radicula, put in boiling water after boiling rear removing crust or peeling and boil, dry.[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.[extracts] " China's book on Chinese herbal medicine ".
Fructus Aurantii [source] this product is the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.July gathers when peel is still green, is two halves from middle part crosscut, dries or cold drying.[nature and flavor] are bitter, pungent, sour, temperature.[return through] returns spleen, stomach warp.[function cures mainly] regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] anemia of pregnant woman is cautious use of.QI and blood weak person can not take.[extracts] " China's book on Chinese herbal medicine ".
Radix Et Rhizoma Rhei [another name] Huang Liang, fire ginseng, skin are as, general, Radixet Rhizoma Rhei, Radix Et Rhizoma Rhei, high, another name for Sichuan Province Radix Et Rhizoma Rhei, cow tongue Radix Et Rhizoma Rhei, bright and beautiful stricture of vagina, raw army, fragrant Radix Et Rhizoma Rhei, R.hoofshaped.[source] this product is the dry root and rhizome of polygonum rheum palmatum, Rheum tanguticum or Rheum officinale.Autumn Mo in the stem and leaf withered or secondary spring excavates before germinateing, and removing radicula, scrapes off crust, valve cutting or section, and rope wears bunchiness drying or convection drying.[nature and flavor] are bitter, cold.[return through] returns spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.[usage and dosage] takes orally: decoct soup, 3 ~ 30g.[attention] blood deficiency gas is weak, Deficiency and coldness of spleen and stomach, without excess-heat, stagnant, stasis, and before tire, puerperal, all should carefully take.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of acute pancreatitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing acute pancreatitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of eczema acute pancreatitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Bupleuri 15 parts, Fructus Aurantii 10 parts, Fructus Aurantii Immaturus 10 parts, Radix Scutellariae 10 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Pinelliae Preparatum l0 part, Radix Et Rhizoma Rhei 6 parts, Fructus Jujubae 15 parts, 3 parts, Rhizoma Zingiberis Recens.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and patients with acute pancreatitis 61 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 32 example and matched group 29 example at random, treatment group man 24 example, female 8 example, 3 ~ 45 years old age, 38.6 years old mean age; Matched group man 22 example, female 7 example, 38.8 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to national acute pancreatitis patients specialized conference: (1), acute pancreatitis patients show as acute persistence stomachache (even without stomachache), and blood amylase activity increases >=upper limits of normal 3 times.Iconography prompting pancreas has or without morphologic change; Get rid of other illness, can to have or without other organ dysfunction; Minority case serum amyloid enzymatic activity normally or slightly increases; (2), mild acute pancreatitis: the clinical manifestation and the Biochemical changes that possess acute pancreatitis, and without organ dysfunction or Local Complications.Good to liquid supplement therapy reaction.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 2 times.14 days courses for the treatment of.
Matched group Effect of Oral Metronidazole, quinolone antibiotic (by specification is taken), 14 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: in 3 d, symptom, sign are alleviated, and disappear in 7 d, blood, amylase in urine are normal.
Effective: in d, symptom, sign significantly take a turn for the better, blood, amylase in urine recover normal;
Effective: in 7 d, symptom, sign alleviate, blood, amylase in urine have downward trend;
Invalid: in 7 d, symptom and sign does not alleviate or worsens, blood, amylase in urine do not reduce;
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
| Group | n | Clinic control | Effective | Effectively | Invalid | Total effective rate (%) | Cure-remarkable-effectiveness rate |
| Treatment group | 32 | 5 | 15 | 10 | 2 | 93.7% | 62.5% |
| Matched group | 29 | 4 | 10 | 13 | 2 | 93.1% | 48.3% |
Visible, the medicine that the present invention obtains can safe and effective treatment acute pancreatitis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Radix Bupleuri 15 grams, Fructus Aurantii 10 grams, Fructus Aurantii Immaturus 10 grams, Radix Scutellariae 10 grams, the Radix Paeoniae Alba 12 grams, Rhizoma Pinelliae Preparatum l0 gram, Radix Et Rhizoma Rhei 6 grams, Fructus Jujubae 15 grams, 3 grams, Rhizoma Zingiberis Recens; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of acute pancreatitis.Oral, every bu is taken for twice sooner or later.
Embodiment 2
Take: Radix Bupleuri 15 grams, Fructus Aurantii 10 grams, Fructus Aurantii Immaturus 10 grams, Radix Scutellariae 10 grams, the Radix Paeoniae Alba 12 grams, Rhizoma Pinelliae Preparatum l0 gram, Radix Et Rhizoma Rhei 6 grams, Fructus Jujubae 15 grams, 3 grams, Rhizoma Zingiberis Recens; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of acute pancreatitis.Oral, every bu is taken for twice sooner or later.
Embodiment 3
Take: Radix Bupleuri 15 grams, Fructus Aurantii 10 grams, Fructus Aurantii Immaturus 10 grams, Radix Scutellariae 10 grams, the Radix Paeoniae Alba 12 grams, Rhizoma Pinelliae Preparatum l0 gram, Radix Et Rhizoma Rhei 6 grams, Fructus Jujubae 15 grams, 3 grams, Rhizoma Zingiberis Recens; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of acute pancreatitis.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of acute pancreatitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Bupleuri 15 parts, Fructus Aurantii 10 parts, Fructus Aurantii Immaturus 10 parts, Radix Scutellariae 10 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Pinelliae Preparatum l0 part, Radix Et Rhizoma Rhei 6 parts, Fructus Jujubae 15 parts, 3 parts, Rhizoma Zingiberis Recens.
2., as claimed in claim 1 for the Chinese medicine of acute pancreatitis, it is characterized in that, its preparation method is: take: Radix Bupleuri 15 parts, Fructus Aurantii 10 parts, Fructus Aurantii Immaturus 10 parts, Radix Scutellariae 10 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Pinelliae Preparatum l0 part, Radix Et Rhizoma Rhei 6 parts, Fructus Jujubae 15 parts, 3 parts, Rhizoma Zingiberis Recens; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of acute pancreatitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix Bupleuri 15 parts, Fructus Aurantii 10 parts, Fructus Aurantii Immaturus 10 parts, Radix Scutellariae 10 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Pinelliae Preparatum l0 part, Radix Et Rhizoma Rhei 6 parts, Fructus Jujubae 15 parts, 3 parts, Rhizoma Zingiberis Recens; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of acute pancreatitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Radix Bupleuri 15 parts, Fructus Aurantii 10 parts, Fructus Aurantii Immaturus 10 parts, Radix Scutellariae 10 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Pinelliae Preparatum l0 part, Radix Et Rhizoma Rhei 6 parts, Fructus Jujubae 15 parts, 3 parts, Rhizoma Zingiberis Recens; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510155166.5A CN104758900A (en) | 2015-04-03 | 2015-04-03 | Traditional Chinese medicine for treating acute pancreatitis |
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| CN201510155166.5A CN104758900A (en) | 2015-04-03 | 2015-04-03 | Traditional Chinese medicine for treating acute pancreatitis |
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| CN104758900A true CN104758900A (en) | 2015-07-08 |
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| CN201510155166.5A Withdrawn CN104758900A (en) | 2015-04-03 | 2015-04-03 | Traditional Chinese medicine for treating acute pancreatitis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105521476A (en) * | 2016-01-12 | 2016-04-27 | 青岛市中心医院 | Granules for treating acute edematous pancreatitis and preparation method of granules |
| CN105596973A (en) * | 2015-10-09 | 2016-05-25 | 淄博夸克医药技术有限公司 | Traditional Chinese medicine for treating acute myelitis |
| WO2019015102A1 (en) * | 2017-07-19 | 2019-01-24 | 淄博夸克医药技术有限公司 | Traditional chinese medicine for treating acute pancreatitis |
-
2015
- 2015-04-03 CN CN201510155166.5A patent/CN104758900A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105596973A (en) * | 2015-10-09 | 2016-05-25 | 淄博夸克医药技术有限公司 | Traditional Chinese medicine for treating acute myelitis |
| CN105521476A (en) * | 2016-01-12 | 2016-04-27 | 青岛市中心医院 | Granules for treating acute edematous pancreatitis and preparation method of granules |
| WO2019015102A1 (en) * | 2017-07-19 | 2019-01-24 | 淄博夸克医药技术有限公司 | Traditional chinese medicine for treating acute pancreatitis |
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Application publication date: 20150708 |