CN109381683A - It is a kind of for treating the Chinese medicine of acute pancreatitis - Google Patents

Abstract

The present invention relates to a kind of for treating the Chinese medicine of acute pancreatitis, it is prepared by the raw medicinal material of following weight proportion: 15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of Radix Paeoniae Alba, l0 parts of rhizoma pinellinae praeparata, 6 parts of prepared RADIX ET RHIZOMA RHEI, 15 parts of jujube, 3 parts of ginger.Clinical experiments have proved that the present invention can safely and effectively treat acute pancreatitis.

Description

It is a kind of for treating the Chinese medicine of acute pancreatitis

Technical field

The present invention relates to a kind of Chinese medicines, and in particular to a kind of for treating the Chinese medicine of acute pancreatitis.

Background technique

Acute pancreatitis is that Different types of etiopathogenises causes pancreatin to activate, using pancreas local inflammation reaction as main feature, companion or not It is clinically common one of acute abdomen with the disease that other organ dysfunctions change, Etiological is that biliary diseases, crapulence are sudden and violent Food, excessive drinking etc., disease incidence rise year by year with the continuous height-regulating of living standard, and the course of disease is dangerous, complication More, case fatality rate height, mechanism do not illustrate completely.The name of disease of " pancreatitis " is had no in motherland's medicine, but ancient literature has The largely similar discussion with pancreatitis symptom etc., " abdominal distension fullness sensation in chest, gastral cavilty is when pained, and two side of body of branch, pharynx diaphragm is obstructed, Gastropathic stomachache." scopes such as motherland's medicine " abdominal pain " " gastropathic stomachache " " epigastric pain " are belonged to according to its genius morbi.Clinic is main To be increased with acute severe abdominal pain, Nausea and vomiting, pancreatin mainly to show.

Medicinal material present Research involved in the present invention is as follows:

It smokes to radix bupleuri [alias], Asia puecon Hu, mountain dish eats grass, faggot.[source] this product is umbelliferae bupleurum or radix bupleuri scorzoneraefolii Dry root.By character difference, practises claim " Bupleurum Chinese " and " RADIX BUPLEURI SCORZONERAEFOLII " respectively.Spring, the excavation of two season of autumn, cauline leaf and silt are removed, It is dry.[nature and flavor] are bitter, slightly cold.[channel tropism] returns liver, gallbladder channel.It is soothing the liver in [major function] and inducing diaphoresis, rising Yang.It is sent out for catching a cold Heat, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, rectal prolapse.[usage and dosage] is for oral administration: decoction, 3~9g.[attention] The dry rhizome of bigleaf thorowax root, the dense link in surface is toxic, can not use when radix bupleuri.[extracts] " China's book on Chinese herbal medicine ".

Three Ye Banxia of the tuber of pinellia [alias], three leaves are old, three steps are jumped, numb semen myristicae, swallow tail, literary, water jade.[source] this product is day The dry tuber of the Southern Star section plant tuber of pinellia.It summer, the excavation of two season of autumn, cleans, removes crust and fibrous root, dry.[nature and flavor] are pungent, Temperature；It is toxic.[channel tropism] returns spleen, stomach, lung channel.[major function] is eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough Asthma, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus；It is raw to use controlling outward carbuncle swells subcutaneous nodule.Ginger half Summer is chiefly used in stopping nausea and vomiting by lowering the adverse flow of QI.[usage and dosage] is for oral administration: decoction, 3~9g.[attention] dry cough due to yin deficiency, injury thirst, blood trouble and sticky sputum Person prohibits clothes, pregnant women should cautiously take.It should not be with Aconitum medicinal material with use.[extracts] " China's book on Chinese herbal medicine ".

Ginger [alias] ginger.[source] this product is the fresh rhizome of zingiber.Autumn, the excavation of two season of winter, remove palpus Root and silt.[nature and flavor] are pungent, tepor.[channel tropism] return lung, spleen, stomach meridian.[major function] relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, resolving sputum stop Cough.For anemofrigid cold, gastrofrigid vomiting, cold productive cough is coughed.[usage and dosage] is for oral administration: decoction, 3~9g.[attention] food ginger is long, accumulated heat Suffer from mesh.All disease hemorrhoid people eat more and wine, and it is very fast to found hair.Ulcerative carbuncle people eats then raw evil meat more.[extracts] " China's book on Chinese herbal medicine ".

Jujube [alias] [source] this product is the dry mature fruit of Rhamnaceae jujube jujube.Autumn fruit at It harvests, dries when ripe.Its root, bark are also used as medicine, and can adopt at any time.[nature and flavor] sweet, warm.[channel tropism] returns spleen, stomach meridian.[major function] Tonifying middle-Jiao and Qi, nourishing blood and tranquilization.For spleen eating less, loose stool out of strength, hysteria of womam.Anti-inflammatory, hemostasis, antidiarrheal.For tracheitis, intestines Inflammation, dysentery, metrorrhagia and metrostaxis；Traumatic hemorrhage is controlled in external application.Promoting the circulation of qi, promoting blood circulation, menstruation regulating.It is red to collapse for irregular menstruation, leukorrhea.[usage and dosage] It is for oral administration: decoction, 6~15g.[attention] is all to be had damp phlegm, stagnates, and tooth disease, worm patient be not suitable.Epigastric fullness, in full vomiter avoid It.Eat dynamic wind, spleen is instead by disease more.[extracts] " China's book on Chinese herbal medicine ".

Radix scutellariae [alias] Radix Scutellariae, scutellaria tea, tsuchikane tea root.[source] this product is the drying of Lamiaceae plant radix scutellariae Root.Spring, the excavation of two season of autumn, fibrous root and silt are removed, rough bark is hit after solarization, dries.[nature and flavor] are bitter, tremble with fear.[channel tropism] return lung, gallbladder, Spleen, large intestine, small intestinl channel.[major function] heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention.It is wet for damp-warm syndrome, heat temperature chest tightness and emesis Hot feeling of fullness, dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, threatened abortion.[usage and dosage] is for oral administration: Decoction, 3-9g.[attention] Fructus Corni, keel make for it.It is real to dislike green onion.Fear cinnabar, tree peony, black false hellebore.[extracts] " China's book on Chinese herbal medicine ".

The dried immature fruit of citron orange [source] this product is the drying young fruit of rutaceae bitter orange and its variety or sweet orange.5~June collects From the fruit fallen, impurity is removed, is cut cross from the middle to two halves, sun drying or low temperature drying, the direct sun drying or low temperature drying of smaller. [nature and flavor] are bitter, pungent, sour, temperature.[channel tropism] returns spleen, stomach meridian.[major function] relieving stagnant Qi disperse accumulation, eliminating phlegm and dispersing mass.For internal stagnation, ruffian Full distending pain, weight after rush down dysentery, constipation, phlegm stagnant gas hinder thoracic obstruction, accumulation of pathogens in chest；Gastroptosis, rectal prolapse, uterine prolapse.In [usage and dosage] Clothes: decoction, 3~9g.[attention] pregnant woman is used with caution.[extracts] " China's book on Chinese herbal medicine ".

Radix Paeoniae Alba [alias] Chinese herbaceous peony.[source] this product is the dry root of ranunculaceae plant Chinese herbaceous peony.It summer, the excavation of two season of autumn, washes Only, it removes end to end and radicula, sets and boiled again after removing crust or peeling after boiling in boiling water, dried.[nature and flavor] are bitter, sour, slightly cold.[return Through] return liver, the spleen channel.[major function] calming the liver and relieving pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating.For headache and dizziness, hypochondriac pain, abdominal pain, four limbs Contraction pain, blood deficiency chlorosis, irregular menstruation, spontaneous perspiration, night sweat.[usage and dosage] is for oral administration: decoction, 6~15g.[attention] unsuitable and black false hellebore With use.[extracts] " China's book on Chinese herbal medicine ".

Fructus Aurantii [source] this product is the drying immature fruit of rutaceae bitter orange and its variety.July pericarp Still green Shi Caishou, cuts cross from the middle to two halves, sun drying or low temperature drying.[nature and flavor] are bitter, pungent, sour, temperature.[channel tropism] returns spleen, stomach Through.[major function] regulating the flow of QI to ease the stomach, the stagnant dissipate-swelling of row.For the chest side of body stagnation of the circulation of vital energy, turgor pain, accumulation of food in the stomach and intes tine due to indigestion stops in phlegm retention；Under stomach It hangs down, rectal prolapse, sub-official prolapses.[usage and dosage] is for oral administration: decoction, 3~9g.[attention] pregnant woman is used with caution.Qi and blood weak person can not take.It [plucks Record] " China's book on Chinese herbal medicine ".

Prepared RADIX ET RHIZOMA RHEI [alias] Huang Liang, fire ginseng, skin as, general, Radixet Rhizoma Rhei, Sichuan troops, high, another name for Sichuan Province rheum officinale, cow tongue rheum officinale, brocade Line, raw army, fragrant rheum officinale, R.hoofshaped.[source] this product is polygonum rheum palmatum, Rheum tanguticum Maxim or Rheum officinale Dry root and rhizome.Autumn end cauline leaf is withered or the preceding excavation of secondary spring germination, removes radicula, scrapes off crust, valve cutting or section, restricts and wear bunchiness Dry or convection drying.[nature and flavor] are bitter, tremble with fear.[channel tropism] returns spleen, stomach, large intestine, liver, pericardium channel.[major function] purges heat logical intestines, cool Blood removing toxic substances, dispelling stasis of blood and stimulating the menstrual flow.For real heat constipation, stagnate abdominal pain, and dysentery is not well, jaundice with damp-heat pathogen, blood-head tells nosebleed, hot eyes, pharynx swelling, intestines Carbuncle abdominal pain, carbuncle swells furunculosis, blood stasis closed, traumatic injury control scald outside；Upper gastrointestinal bleeding.Rheum palmatum (processed with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs blood Divide heat toxin.For hot eyes pharynx swelling, gingivitis.Prepared RADIX ET RHIZOMA RHEI, which rushes down, to be exerted oneself to delay, purging fire for removing toxin.For pathogenic fire,toxin and furuncles.Charred RADIX ET RHIZOMA RHEI cool blood Removing blood stasis and hemostasis.There is stasis of blood haemorrhage for blood-head.[usage and dosage] is for oral administration: decoction, 3~30g.[attention] deficiency of blood gas is weak, and taste are empty It is cold, before no real heat, stagnant, stasis and tire, postpartum, careful it should all take.[extracts] " China's book on Chinese herbal medicine ".

Summary of the invention

The present invention is intended to provide it is a kind of for treating the Chinese medicine of acute pancreatitis, by selecting suitable medicinal material and its matching Than achieving the purpose that safely and effectively to cure acute pancreatitis.

In order to achieve the above object, the invention adopts the following technical scheme:

It is a kind of for treating the Chinese medicine of eczema acute pancreatitis, which is characterized in that it is by the raw medicinal material of following weight proportion It is prepared: 15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of Radix Paeoniae Alba, rhizoma pinellinae praeparata L0 parts, 6 parts of prepared RADIX ET RHIZOMA RHEI, 15 parts of jujube, 3 parts of ginger.

The beneficial effects of the present invention will now be described with reference to clinical experimental data:

1, general information

Outpatient service and in hospital patients with acute pancreatitis 61 are collected between October in inventor in October, 2012 ~ 2013 year altogether, are randomly divided into Treatment group 32 and control group 29, treatment group male 24, female 8, the age 3~45 years old, average age 38.6 years old；Control group male 22, female 7, average age 38.8 years old.2 groups of genders, age and course of disease comparing difference are not statistically significant, are comparable.

Diagnostic criteria

Diagnostic criteria according to national acute pancreatitis patients specialized conference: (1), acute pancreatitis patients show as it is acute lasting Property abdominal pain (even without abdominal pain), blood amylase activity increases >=3 times of normal upper limit.Iconography prompt pancreas changes with or without form Become；Other illness are excluded, it can be with or without other organ dysfunctions；A small number of case serum amyloid enzymatic activitys are normal or slightly increase It is high；(2), mild acute pancreatitis: having clinical manifestation and the Biochemical changes of acute pancreatitis, and without organ dysfunction or office Portion's complication.It is good to liquid supplementary therapy reaction.

2, test method

2.1 treatment method

The oral present invention for the treatment of group is according to capsule made from specific embodiment 3,2 times a day.The course for the treatment of 14 days.

Control group Effect of Oral Metronidazole, quinolone antibiotics (by specification is taken), the course for the treatment of 14 days.

3, criterion of therapeutical effect and treatment results

3.1 criterion of therapeutical effect

Clinic control: symptom, sign are alleviated in 3 d, disappear in 7 d, blood, amylase in urine are normal.

Effective: symptom, sign significantly improve in d, and blood, amylase in urine restore normal；

Effective: symptom, sign mitigate in 7 d, and blood, amylase in urine have downward trend；

Invalid: symptom and sign does not mitigate or deteriorates in 7 d, and blood, amylase in urine do not reduce；

3.2 treatment results are shown in Table 1.

1 two groups of curative effects of table compare

Group	n	Clinic control	It is effective	Effectively	In vain	Total effective rate (%)	Cure-remarkable-effectiveness rate
								Treatment group	32	5	15	10	2	93.7%	62.5%
Control group	29	4	10	13	2	93.1%	48.3%

As it can be seen that drug produced by the present invention can safely and effectively treat acute pancreatitis, there is promotional value.

Specific embodiment

In order to better understand and implement the present invention, the present invention is further illustrated combined with specific embodiments below.

Embodiment 1

It weighs: 15 grams of radix bupleuri, 10 grams of Fructus Aurantii, 10 grams of the dried immature fruit of citron orange, 10 grams of radix scutellariae, 12 grams of Radix Paeoniae Alba, rhizoma pinellinae praeparata l0 Gram, 6 grams of prepared RADIX ET RHIZOMA RHEI, 15 grams of jujube, 3 grams of ginger；Add 8 times of amount water, decocts 1.5 hours, filtering；Filter residue adds 6 times of amounts Water decocts 1 hour, filtering；Merging filtrate is concentrated into 120 grams to get the decoction for meeting one day dosage of normal adult.

For treating acute pancreatitis.Oral, every bu is taken twice sooner or later.

Embodiment 2

It weighs: 15 grams of radix bupleuri, 10 grams of Fructus Aurantii, 10 grams of the dried immature fruit of citron orange, 10 grams of radix scutellariae, 12 grams of Radix Paeoniae Alba, rhizoma pinellinae praeparata l0 Gram, 6 grams of prepared RADIX ET RHIZOMA RHEI, 15 grams of jujube, 3 grams of ginger；Add 10 times of amount water, decocts 2 hours, filtering；Filter residue adds 8 times of amounts Water decocts 1.5 hours, filtering；Merging filtrate is concentrated, dry, packs to get the powder for meeting one day dosage of normal adult.

For treating acute pancreatitis.Oral, every bu is taken twice sooner or later.

Embodiment 3

It weighs: 15 grams of radix bupleuri, 10 grams of Fructus Aurantii, 10 grams of the dried immature fruit of citron orange, 10 grams of radix scutellariae, 12 grams of Radix Paeoniae Alba, rhizoma pinellinae praeparata l0 Gram, 6 grams of prepared RADIX ET RHIZOMA RHEI, 15 grams of jujube, 3 grams of ginger；Add 6 times of amount water, decoct 3 times, decoct 1 hour every time, merges and decoct Boil liquid is concentrated, dry, is packed into capsule shells to get the capsule for meeting one day dosage of normal adult.

For treating acute pancreatitis.Oral, every bu is taken twice sooner or later.

Claims (4)

1. a kind of for treating the Chinese medicine of acute pancreatitis, which is characterized in that it is by the raw medicinal material system of following weight proportion It is standby to form: 15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of Radix Paeoniae Alba, rhizoma pinellinae praeparata l0 Part, 6 parts of prepared RADIX ET RHIZOMA RHEI, 15 parts of jujube, 3 parts of ginger.

2. being used for the Chinese medicine of acute pancreatitis as described in claim 1, which is characterized in that preparation method are as follows: weigh: radix bupleuri 15 parts, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of Radix Paeoniae Alba, l0 parts of rhizoma pinellinae praeparata, prepared RADIX ET RHIZOMA RHEI 6 Part, 15 parts of jujube, 3 parts of ginger；Add 8 times of amount water, decocts 1.5 hours, filtering；Filter residue adds 6 times of amount water, decocts 1 hour, Filtering；Merging filtrate is concentrated into 120 parts to get decoction；Above-mentioned part each means parts by weight.

3. as described in claim 1 for treating the Chinese medicine of acute pancreatitis, which is characterized in that preparation method are as follows: weigh: It is 15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of Radix Paeoniae Alba, l0 parts of rhizoma pinellinae praeparata, ripe 6 parts of rheum officinale, 15 parts of jujube, 3 parts of ginger；Add 10 times of amount water, decocts 2 hours, filtering；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate is concentrated, dry, packs to get powder；Above-mentioned part each means parts by weight.

4. as described in claim 1 for treating the Chinese medicine of acute pancreatitis, which is characterized in that preparation method are as follows: weigh: It is 15 parts of radix bupleuri, 10 parts of Fructus Aurantii, 10 parts of the dried immature fruit of citron orange, 10 parts of radix scutellariae, 12 parts of Radix Paeoniae Alba, l0 parts of rhizoma pinellinae praeparata, ripe 6 parts of rheum officinale, 15 parts of jujube, 3 parts of ginger；Add 6 times of amount water, decoct 3 times, decoct 1 hour every time, merges decoction liquor, it is dense Contracting, it is dry, capsule shells are packed into get capsule；Above-mentioned part each means parts by weight.